ascorbic-acid has been researched along with diacetamate* in 1 studies
1 other study(ies) available for ascorbic-acid and diacetamate
Article | Year |
---|---|
Analysis of tablets containing aspirin, acetaminophen, and ascorbic acid by high-performance liquid chromatography.
The high-performance liquid chromatographic method described enables the quantitation of the components and the main impurities of tablets containing aspirin, acetaminophen, and ascorbic acid. A C8 reverse-phase column was used; the mobile phase was methanol-0.2 M phosphate buffer (pH 3.5)-water (20:10:70). Results obtained for a brand of effervescent tablets, normally aged for 5 years and stressed at 37 degrees C, 50 degrees C, or in 79% relative humidity at room temperature, are reported. Salicylic acid was the main product of decomposition. Diacetyl-p-aminophenol was observed to be formed by transacetylation. Topics: Acetaminophen; Ascorbic Acid; Aspirin; Chromatography, High Pressure Liquid; Drug Stability; Humidity; Hydrogen-Ion Concentration; Salicylates; Salicylic Acid; Tablets; Temperature; Time Factors | 1984 |