ascorbic-acid has been researched along with calcium-lactate* in 3 studies
3 other study(ies) available for ascorbic-acid and calcium-lactate
| Article | Year |
|---|---|
Study of the impacts of electro-activated solutions of calcium lactate, calcium ascorbate and their equimolar mixture combined with moderate heat treatments on the spores of Bacillus cereus ATCC 14579 under model conditions and in fresh salmon.
Topics: Animals; Ascorbic Acid; Bacillus cereus; Calcium Compounds; Colony Count, Microbial; Food Contamination; Food Microbiology; Hot Temperature; Lactates; Salmo salar; Seafood; Spores, Bacterial | 2021 |
Antioxidant and micronutrient-rich milk formula reduces lead poisoning and related oxidative damage in lead-exposed mice.
Lead poisoning is a global environmental disease that induces lifelong adverse health effects. The effect of a milk formula consisting of antioxidant of bamboo leaves (AOB), vitamin C (Vc), calcium lactate (CaLac), ferrous sulfate (FeSO₄) and zinc sulfate (ZnSO₄) on the reduction of lead and lead-induced oxidative damage in lead-exposed mice was studied. The lead-reducing effect of milk formula was investigated via a 7-week toxicokinetics study and a tissue distribution level examination. The ameliorating effect of milk formula on lead-induced oxidative damage was investigated. Results demonstrated current milk formula could effectively reduce blood lead levels (BLLs) and lead distribution levels of liver, kidneys, thighbones and brain in mice based on metal ion-mediated antagonism and chelation mechanisms. This milk formula could not only protect lead-susceptible tissues against lead poisoning, but also maintain normal absorption and distribution of essential elements in vivo. Meanwhile, current milk formula could prevent the reduction of δ-aminolevulinic acid dehydratase (δ-ALAD) activity and enhancement of free erythrocyte protoporphyrins (FEP) levels in blood erythrocytes of mice. Also, this formula could indirectly protect blood cell membranes against lead-induced lipid peroxidation. We conclude that current optimized milk formula effectively reduces lead poisoning and lead-induced in vivo oxidative damage in lead-exposed mice. Topics: Animals; Antioxidants; Ascorbic Acid; Calcium Compounds; Ferrous Compounds; Food, Formulated; Lactates; Lead; Lead Poisoning; Male; Mice; Mice, Inbred ICR; Micronutrients; Milk; Oxidative Stress; Porphobilinogen Synthase; Reproducibility of Results; Sasa; Spectrophotometry, Atomic; Tissue Distribution; Zinc Sulfate | 2013 |
Supplement nephropathy due to long-term, high-dose ingestion of ascorbic acid, calcium lactate, vitamin D and laxatives.
A 48-year-old Japanese woman previously in good health was found to have severe proximal tubular dysfunction with a high serum level of ascorbic acid (57.3 microg/ml, reference range: 1.9 - 15.0 microg/ml). Renal biopsy specimen showed marked tubulointerstitial damage, i.e. tubular atrophy, dilatation of tubular lumen with flattened tubular epithelial cells, vacuolization of proximal and distal tubular epithelial cells, and severe interstitial fibrosis with mild infiltration of mononuclear cells. Calcified lesions, which caused tubular obstruction or stenosis, were also seen in interstitial area adjacent to degenerated proximal tubuli. Hypokalemic nephropathy, probably due to long-term use of laxatives, was clearly shown. However, calcified lesions seemed to be caused by inappropriate excessive daily ingestion of ascorbic acid (6 000 mg/day), calcium lactate, and vitamin D because of the patient's misunderstanding that these supplements could keep her in a good health. This condition may be clinically called "supplement nephropathy". Topics: Ascorbic Acid; Biopsy; Calcium Compounds; Cathartics; Dietary Supplements; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Kidney Glomerulus; Lactates; Middle Aged; Nephritis, Interstitial; Time Factors; Vitamin D; Vitamins | 2005 |