ascorbic-acid and cadmium-sulfate

ascorbic-acid has been researched along with cadmium-sulfate* in 2 studies

Other Studies

2 other study(ies) available for ascorbic-acid and cadmium-sulfate

Article	Year
In situ enzymatic ascorbic acid production as electron donor for CdS quantum dots equipped TiO2 nanotubes: a general and efficient approach for new photoelectrochemical immunoassay. Analytical chemistry, 2012, Dec-18, Volume: 84, Issue:24 In this work, a novel photoelectrochemical (PEC) immunoanalysis format was developed for sensitive and specific detection of prostate-specific antigen (PSA) based on an in situ electron donor producing approach. Thioglycolic acid-capped CdS quantum dots (QDs) equipped TiO(2) nanotubes (NTs) were fabricated via a facile electrostatic adsorption method. The coupling of CdS QDs and TiO(2) NTs results in an enhanced excitation and photo-to-electric conversion efficiency. Using alkaline phosphatase catalytic chemistry to in situ generate ascorbic acid for electron donating, an exquisite immunosandwich protocol was successfully constructed for the PSA assay due to the dependence of the photocurrent signal on the concentration of electron donor. This work opens a different perspective for transducer design in PEC detection and provides a general format for future development of PEC immunoanalysis. Topics: Ascorbic Acid; Biosensing Techniques; Cadmium Compounds; Electrochemical Techniques; Nanotubes; Photochemical Processes; Quantum Dots; Sulfates; Titanium	2012
[Cadmium-induced changes in the activity of the dopaminergic and purinergic systems and in ascorbic acid catabolism in the rat striatum]. La Clinica terapeutica, 1991, May-31, Volume: 137, Issue:4 Levels of dopamine (DA), 3-4-dihydroxyphenylacetic acid (DOPAC), ascorbic acid (AA), dehydroascorbic acid (DHAA), uric acid (UA) and adenosine (ADO), were determined by HPLC in the striatum of male Wistar rats treated with repeated injections of cadmium (as sulfate) 3 mg/kg/day s.c. for 10 consecutive days. Cadmium treatment significantly reduced DOPAC levels with consequent decrease of the DOPAC/DA ratio; AA levels were significantly reduced, while DHAA levels were significantly increased, with consequent increase of DHAA/AA ratio: levels of UA and ADO were both significantly increased. It is concluded that cadmium, given systemically, reduces dopaminergic system activity in the rat striatum; such impairment occurs together with an increase of AA oxidation and of markers of purinergic system activity. The inhibition of striatal dopaminergic activity could be considered the neurochemical basis of behavioral changes induced by cadmium, while the increase of AA oxidation and of purinergic system activity could be considered an antitoxic metabolic response. Topics: Adenosine; Animals; Ascorbic Acid; Cadmium; Cadmium Compounds; Corpus Striatum; Dopamine; Male; Rats; Receptors, Dopamine; Receptors, Purinergic; Sulfates; Uric Acid	1991

Article

Year

In situ enzymatic ascorbic acid production as electron donor for CdS quantum dots equipped TiO2 nanotubes: a general and efficient approach for new photoelectrochemical immunoassay.

Analytical chemistry, 2012, Dec-18, Volume: 84, Issue:24

In this work, a novel photoelectrochemical (PEC) immunoanalysis format was developed for sensitive and specific detection of prostate-specific antigen (PSA) based on an in situ electron donor producing approach. Thioglycolic acid-capped CdS quantum dots (QDs) equipped TiO(2) nanotubes (NTs) were fabricated via a facile electrostatic adsorption method. The coupling of CdS QDs and TiO(2) NTs results in an enhanced excitation and photo-to-electric conversion efficiency. Using alkaline phosphatase catalytic chemistry to in situ generate ascorbic acid for electron donating, an exquisite immunosandwich protocol was successfully constructed for the PSA assay due to the dependence of the photocurrent signal on the concentration of electron donor. This work opens a different perspective for transducer design in PEC detection and provides a general format for future development of PEC immunoanalysis.

Topics: Ascorbic Acid; Biosensing Techniques; Cadmium Compounds; Electrochemical Techniques; Nanotubes; Photochemical Processes; Quantum Dots; Sulfates; Titanium

2012

[Cadmium-induced changes in the activity of the dopaminergic and purinergic systems and in ascorbic acid catabolism in the rat striatum].

La Clinica terapeutica, 1991, May-31, Volume: 137, Issue:4

Levels of dopamine (DA), 3-4-dihydroxyphenylacetic acid (DOPAC), ascorbic acid (AA), dehydroascorbic acid (DHAA), uric acid (UA) and adenosine (ADO), were determined by HPLC in the striatum of male Wistar rats treated with repeated injections of cadmium (as sulfate) 3 mg/kg/day s.c. for 10 consecutive days. Cadmium treatment significantly reduced DOPAC levels with consequent decrease of the DOPAC/DA ratio; AA levels were significantly reduced, while DHAA levels were significantly increased, with consequent increase of DHAA/AA ratio: levels of UA and ADO were both significantly increased. It is concluded that cadmium, given systemically, reduces dopaminergic system activity in the rat striatum; such impairment occurs together with an increase of AA oxidation and of markers of purinergic system activity. The inhibition of striatal dopaminergic activity could be considered the neurochemical basis of behavioral changes induced by cadmium, while the increase of AA oxidation and of purinergic system activity could be considered an antitoxic metabolic response.

Topics: Adenosine; Animals; Ascorbic Acid; Cadmium; Cadmium Compounds; Corpus Striatum; Dopamine; Male; Rats; Receptors, Dopamine; Receptors, Purinergic; Sulfates; Uric Acid

1991