ascorbic-acid and bergenin

ascorbic-acid has been researched along with bergenin* in 2 studies

Other Studies

2 other study(ies) available for ascorbic-acid and bergenin

Article	Year
A new bergenin derivative from the rhizome of Ardisia gigantifolia. Natural product research, 2013, Volume: 27, Issue:14 One new bergenin derivative, named 11-O-veratroylbergenin (1) along with five known bergenin derivatives, 11-O-(3'-O-methylgalloyl) bergenin (2), 11-O-syringylbergenin (3), 11-O-Galloylbergenin (4), 4-O-Galloylbergenin (5) and bergenin (6) were isolated from Ardisia gigantifolia Stapf. Their structures were established on the basis of spectroscopic analysis, especially by means of 1D, 2D-NMR and HR-ESIMS analyses. Compounds 2, 4 and 5 showed significant 2,2-diphenyl-1-picrylhydrazyl (DPPH) free-radical scavenging activity with EC₅₀ 9.7, 9.0 and 7.8 µmol L(-1), respectively. They showed more antioxidant activity than the positive control vitamin C (EC₅₀ = 28.3 µmol L(-1)). Topics: Ardisia; Ascorbic Acid; Benzopyrans; Free Radical Scavengers; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Plant Extracts; Rhizome	2013
Chemical constituents of Caesalpinia decapetala (Roth) Alston. Molecules (Basel, Switzerland), 2013, Jan-22, Volume: 18, Issue:1 The current study targets the chemical constituents of Caesalpinia decapetala (Roth) Alston and investigates the bioactivities of the isolated compounds. Fourteen known compounds were isolated using column chromatography, and structural identification was performed by physical and spectral analyses. The biological activities of the compounds were also evaluated by 3-(4,5-dimethythiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) and 2,2-diphenlyl-1-picrylhydrazyl (DPPH) assays. Emodin (6), baicalein (9), and apigenin (12) displayed antitumor activities against the MGC-803 cell line, while quercetin (2), rutin (5), baicalein (9), and epicatechin (13) showed stronger DPPH scavenging activities compared with ascorbic acid. Andrographolide (1), quercetin (2), bergenin (4), rutin (5), emodin (6), betulin (7), baicalein (9), polydatin (10), salicin (11), and apigenin (12), were obtained from C. decapetala (Roth) Alston for the first time. Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Ascorbic Acid; Benzopyrans; Benzyl Alcohols; Biphenyl Compounds; Caesalpinia; Cell Line, Tumor; Cell Survival; Emodin; Flavonoids; Free Radical Scavengers; Free Radicals; Glucosides; Humans; Inhibitory Concentration 50; Molecular Structure; Picrates; Plant Extracts; Stilbenes; Triterpenes	2013

Article

Year

A new bergenin derivative from the rhizome of Ardisia gigantifolia.

Natural product research, 2013, Volume: 27, Issue:14

One new bergenin derivative, named 11-O-veratroylbergenin (1) along with five known bergenin derivatives, 11-O-(3'-O-methylgalloyl) bergenin (2), 11-O-syringylbergenin (3), 11-O-Galloylbergenin (4), 4-O-Galloylbergenin (5) and bergenin (6) were isolated from Ardisia gigantifolia Stapf. Their structures were established on the basis of spectroscopic analysis, especially by means of 1D, 2D-NMR and HR-ESIMS analyses. Compounds 2, 4 and 5 showed significant 2,2-diphenyl-1-picrylhydrazyl (DPPH) free-radical scavenging activity with EC₅₀ 9.7, 9.0 and 7.8 µmol L(-1), respectively. They showed more antioxidant activity than the positive control vitamin C (EC₅₀ = 28.3 µmol L(-1)).

Topics: Ardisia; Ascorbic Acid; Benzopyrans; Free Radical Scavengers; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Plant Extracts; Rhizome

2013

Chemical constituents of Caesalpinia decapetala (Roth) Alston.

Molecules (Basel, Switzerland), 2013, Jan-22, Volume: 18, Issue:1

The current study targets the chemical constituents of Caesalpinia decapetala (Roth) Alston and investigates the bioactivities of the isolated compounds. Fourteen known compounds were isolated using column chromatography, and structural identification was performed by physical and spectral analyses. The biological activities of the compounds were also evaluated by 3-(4,5-dimethythiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) and 2,2-diphenlyl-1-picrylhydrazyl (DPPH) assays. Emodin (6), baicalein (9), and apigenin (12) displayed antitumor activities against the MGC-803 cell line, while quercetin (2), rutin (5), baicalein (9), and epicatechin (13) showed stronger DPPH scavenging activities compared with ascorbic acid. Andrographolide (1), quercetin (2), bergenin (4), rutin (5), emodin (6), betulin (7), baicalein (9), polydatin (10), salicin (11), and apigenin (12), were obtained from C. decapetala (Roth) Alston for the first time.

Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Ascorbic Acid; Benzopyrans; Benzyl Alcohols; Biphenyl Compounds; Caesalpinia; Cell Line, Tumor; Cell Survival; Emodin; Flavonoids; Free Radical Scavengers; Free Radicals; Glucosides; Humans; Inhibitory Concentration 50; Molecular Structure; Picrates; Plant Extracts; Stilbenes; Triterpenes

2013