ascladiol has been researched along with furan* in 1 studies
1 other study(ies) available for ascladiol and furan
Article | Year |
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Divergent synthesis of the co-isolated mycotoxins longianone, isopatulin, and (Z)-ascladiol via furan oxidation.
Longianone and the biosynthetically related mycotoxins isopatulin and (Z)-ascladiol were prepared following a divergent route from a readily available furan diol. The route toward longianone features an unprecedented TBAF-promoted intramolecular oxa-Michael reaction to a conjugated keto enoate, and the oxidation of dihydrolongianone to longianone with stabilized IBX. The route to isopatulin features a chemoenzymatic synthesis of (Z)-ascladiol, and the regioselective oxidation of (Z)-ascladiol to isopatulin with MnO(2). Topics: Furans; Heterocyclic Compounds, 2-Ring; Lactones; Mycotoxins; Oxidation-Reduction; Spiro Compounds; Stereoisomerism | 2009 |