asbestos--crocidolite and 5-5-dimethyl-1-pyrroline-1-oxide

asbestos--crocidolite has been researched along with 5-5-dimethyl-1-pyrroline-1-oxide* in 1 studies

Other Studies

1 other study(ies) available for asbestos--crocidolite and 5-5-dimethyl-1-pyrroline-1-oxide

Article	Year
Spin trapping of superoxide released by opsonized asbestos from human promyelocytic leukemia cell line, HL60. Biochemical and biophysical research communications, 1993, Jul-15, Volume: 194, Issue:1 By ESR using 5,5-dimethyl-1-pyrroline-1-oxide as a spin trap, superoxide (O2-) production was proved upon stimulation of dimethyl sulfoxide-differentiated HL60 by crocidolite opsonized with fresh or refrigerated serum, as well as by phorbol myristate acetate (PMA). Crocidolite, unopsonized or opsonized with frozen-thawed or heat-inactivated serum, did not induce O2- release. Addition of iron chelators or superoxide dismutase inhibited O2- release completely. Neither undifferentiated nor PMA-differentiated HL60 released O2- upon stimulation with opsonized crocidolite. Topics: Asbestos; Asbestos, Crocidolite; Cell Differentiation; Cyclic N-Oxides; Deferoxamine; Dimethyl Sulfoxide; Electron Spin Resonance Spectroscopy; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Pentetic Acid; Spin Labels; Superoxides; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured	1993

Article

Year

Spin trapping of superoxide released by opsonized asbestos from human promyelocytic leukemia cell line, HL60.

Biochemical and biophysical research communications, 1993, Jul-15, Volume: 194, Issue:1

By ESR using 5,5-dimethyl-1-pyrroline-1-oxide as a spin trap, superoxide (O2-) production was proved upon stimulation of dimethyl sulfoxide-differentiated HL60 by crocidolite opsonized with fresh or refrigerated serum, as well as by phorbol myristate acetate (PMA). Crocidolite, unopsonized or opsonized with frozen-thawed or heat-inactivated serum, did not induce O2- release. Addition of iron chelators or superoxide dismutase inhibited O2- release completely. Neither undifferentiated nor PMA-differentiated HL60 released O2- upon stimulation with opsonized crocidolite.

Topics: Asbestos; Asbestos, Crocidolite; Cell Differentiation; Cyclic N-Oxides; Deferoxamine; Dimethyl Sulfoxide; Electron Spin Resonance Spectroscopy; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Pentetic Acid; Spin Labels; Superoxides; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured

1993