artonin-e and morusin

artonin-e has been researched along with morusin* in 1 studies

Other Studies

1 other study(ies) available for artonin-e and morusin

Article	Year
A prenylflavone, artonin E, as arachidonate 5-lipoxygenase inhibitor. Biochemical pharmacology, 1991, Jan-01, Volume: 41, Issue:1 Several naturally occurring prenylflavones were tested for their inhibitory actions on arachidonate 5-lipoxygenase purified from porcine leukocytes. Of the compounds tested, artonin E (5'-hydroxymorusin) exhibited the most potent inhibition on arachidonate 5-lipoxygenase (IC50 = 0.36 microM). Arachidonate 12-lipoxygenase purified from porcine leukocytes and human platelets, 15-lipoxygenase from rabbit reticulocytes and fatty acid cyclooxygenase from bovine vesicular glands were inhibited by the compound only at higher concentrations (IC50 = 2.3, 11, 5.2 and 2.5 microM, respectively). Topics: Animals; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Flavonoids; Humans; Leukocytes; Lipoxygenase Inhibitors; Structure-Activity Relationship	1991

Article

Year

A prenylflavone, artonin E, as arachidonate 5-lipoxygenase inhibitor.

Biochemical pharmacology, 1991, Jan-01, Volume: 41, Issue:1

Several naturally occurring prenylflavones were tested for their inhibitory actions on arachidonate 5-lipoxygenase purified from porcine leukocytes. Of the compounds tested, artonin E (5'-hydroxymorusin) exhibited the most potent inhibition on arachidonate 5-lipoxygenase (IC50 = 0.36 microM). Arachidonate 12-lipoxygenase purified from porcine leukocytes and human platelets, 15-lipoxygenase from rabbit reticulocytes and fatty acid cyclooxygenase from bovine vesicular glands were inhibited by the compound only at higher concentrations (IC50 = 2.3, 11, 5.2 and 2.5 microM, respectively).

Topics: Animals; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Flavonoids; Humans; Leukocytes; Lipoxygenase Inhibitors; Structure-Activity Relationship

1991