artenimol has been researched along with sesquiterpenes in 240 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (8.75) | 18.7374 |
| 1990's | 83 (34.58) | 18.2507 |
| 2000's | 136 (56.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Leskovac, V; Peggins, JO | 1 |
| Edwards, G; Thomas, CG; Ward, SA | 1 |
| Gosser, DK; Meshnick, SR; Zhang, F | 1 |
| Andersen, SL; Klayman, DL; Li, LQ; Lin, AJ | 1 |
| Leskovac, V; Theoharides, AD | 1 |
| Huo, JZ; Xia, WJ; Xue, M; Zhou, ZT | 1 |
| Brewer, TG; Melendez, V; Peggins, JO; Theoharides, AD | 1 |
| Ayalp, A; Bishop, SJ; el-Feraly, FS; Tawfik, AF | 1 |
| Song, ZY; Zhao, KC | 3 |
| Klayman, DL; Lee, M; Lin, AJ | 1 |
| Du, YL; Li, CS; Zhang, CL; Zhao, XJ | 1 |
| Gu, HM; Peters, W; Warhurst, DC | 3 |
| Cao, XL; Wang, ZS | 1 |
| Li, ZL; Peters, W; Robinson, BL; Warhurst, DC | 1 |
| Ashmore, RW; Halverson, JM; Lin, AJ; Ridder, WE; Smyth, MH; Theoharides, AD; Zhou, ZM | 1 |
| Chen, DX; Ma, JM; Sun, JH; Yang, SD | 1 |
| Anders, JC; Chung, H; Theoharides, AD; Zhou, ZM | 1 |
| Cooke, DW; Durack, DT; Lallinger, GJ | 1 |
| Klayman, DL; Lin, AJ; Milhous, WK | 1 |
| Chen, YX; Ji, RY; Li, Y; Yu, PL | 3 |
| Ellis, DS; Gu, HM; Li, ZL; Peters, W; Robinson, BL; Tovey, G; Warhurst, DC | 1 |
| Ma, JM; Song, ZY; Sun, JH; Yang, SD | 1 |
| Li, CH; Li, R; Li, X; Liao, ZY; Zhong, JJ; Zhou, LL | 1 |
| Gu, HM; Li, ZL; Peters, W; Warhurst, DC | 1 |
| Carlqvist, J; Edlund, PO; Jin, YH; Westerlund, D; Wu, BL | 1 |
| Asokan, M; Chin, LK; Mansor, SM; Mordi, MN; Nair, NK; Navaratnam, V | 1 |
| Gao, HL; Long, ZZ; Ma, DL; Xie, SS; Yang, SX | 1 |
| Lai, H; Singh, NP | 2 |
| Baker, JK; Ramu, K | 1 |
| Mberu, EK; Muhia, DK; Watkins, WM | 1 |
| Lin, AJ; Miller, RE | 1 |
| Asawamahasakda, W; Ittarat, I; Meshnick, SR; Pu, YM; Ziffer, H | 1 |
| Ager, AL; Klayman, DL; Lin, AJ | 1 |
| Fu, LC; Guo, XB; Jian, HX; Li, GQ; Wang, XH | 1 |
| Janse, CJ; Kos, J; Lugt, CB; Waters, AP | 1 |
| Edwards, G; Mberu, EK; Muhia, DK; Thomas, CG; Ward, SA; Watkins, WM | 1 |
| Asawamahasakda, W; Benakis, A; Meshnick, SR | 1 |
| Edwards, G; Karbwang, J; Na Bangchang, K; Sukontason, K; Thanavibul, A; Thomas, CG; Ward, SA | 1 |
| Guo, XB | 1 |
| Baker, JK; Chi, HT; McChesney, JD | 1 |
| Gao, HL; Long, ZZ; Xie, SS; Yang, SX | 1 |
| Chou, CK; Lai, H; Li, JR; McDougall, JA; Moore, JC; Ren, RL; Singh, NP | 1 |
| Avery, MA; Bonk, JD; Chong, WK; Goins, DK; Khan, I; Mehrotra, S; Milhous, W; Miller, R; Venkatesan, S; Wyandt, C | 1 |
| Anh, TK; Batty, KT; Binh, TQ; Davis, TM; Ilett, KF; Thu, LT | 1 |
| Batty, KT; Davis, ME; Davis, T; Ilett, KF | 1 |
| Kraisintu, K; Looareesuwan, S; Pitisuttithum, P; Vanijanonta, S; Viravan, C; Wilairatana, P | 1 |
| Davis, TM; Johnston, WA; Manning, LS; Skinner, TS | 1 |
| Hossler, P; Kamchonwongpaisan, S; McKeever, P; Meshnick, SR; Ziffer, H | 1 |
| Benakis, A; Loutan, L; Paris, M; Plessas, CT; Plessas, ST | 1 |
| Heppner, DG; Kawamoto, F; Nguyen, TD; Sookto, P; Trieu, NT; Wimonwattrawatee, T; Wongsrichanalai, C | 1 |
| Banmairuroi, V; Congpuong, K; Karbwang, J; Molunto, P; Na-Bangchang, K | 1 |
| Kyle, DE; Lin, AJ; Zikry, AB | 1 |
| Donker, M; Godbillon, J; Netter, C; Sandrenan, N; Sioufi, A; van Valkenburg, C | 1 |
| Mansor, SM; Mordi, MN; Navaratnam, V; Wernsdorfer, WH | 1 |
| Mansor, SM; Mordi, MN; Navaratnam, V | 1 |
| Bishop, LP; Madden, S; Maggs, JL; O'Neill, PM; Park, BK | 1 |
| Aguilar, T; Brewer, TG; Grace, JM; Leo, KU; Li, Q; Mitchell, AL; Peggins, J | 1 |
| Butter, JJ; Portier, EJ; van Agtmael, MA; van Boxtel, CJ | 1 |
| Batty, KT; Binh, TQ; Davis, TM; Hung, NC; Ilett, KF; Kim, NV; Mai, TX; Powell, SM; Thien, HV; Thu, LT; Tien, NP | 1 |
| Vattanaviboon, P; Wilairat, P; Yuthavong, Y | 1 |
| Congpoung, K; Karbwang, J; Na-Bangchang, K; Thanavibul, A; Ubalee, R | 1 |
| Brewer, TG; Fleckenstein, LL; Heiffer, MH; Li, QG; Masonic, K; Peggins, JO | 1 |
| Aguilar, AJ; Brewer, TG; Grace, JM; Peggins, JO; Trotman, KM | 1 |
| Berens, RL; Curiel, TJ; Krug, EC; Nash, PB | 1 |
| Benakis, A; Halpaap, B; Kremsner, PG; Ndjave, M; Paris, M | 1 |
| Dong, Y; Huang, KG; Liao, MZ; Liu, DQ; Yang, HL; Yang, PF; Yang, YM; Zhang, CY | 1 |
| Congpuong, K; Karbwang, J; Molunto, P; Na-Bangchang, K; Thanavibul, A; Wattanakoon, Y | 1 |
| Karbwang, J; Molunto, P; Na-Bangchang, K; Thanavibul, A | 1 |
| Edwards, G; Fishwick, J; McLean, WG; Ward, SA | 2 |
| Bhisutthibhan, J; Carlton, J; Dame, JB; Hossler, PA; Meshnick, SR; Pan, XQ; Walker, DJ; Yowell, CA | 1 |
| Congpuong, K; Hung, LN; Karbwang, J; Molunto, P; Na-Bangchang, K | 1 |
| Congpoung, K; Karbwang, J; Na-Bangchang, K; Tan-anya, P; Thanavibul, A; Ubalee, R | 1 |
| Harinasuta, T; Karbwang, J; Na-Bangchang, K; Rimchala, W; Sukontason, K; Tin, T | 1 |
| Abdullah, MN; Akbar, A; Mansor, SM; Mordi, MN; Navaratnam, V | 1 |
| Chalermrut, K; Chanthavanich, P; Kraisintu, K; Krudsood, S; Looareesuwan, S; Phisalaphong, C; Singhasivanon, P; Treeprasertsuk, S; Wilairatana, P | 1 |
| Bégué, JP; Bonnet-Delpon, D; Doury, JC; Gantier, JC; Ménage, C; Pradines, B; Thac, TD; Thanh Nga, TT | 1 |
| Batty, KT; Davis, TM; Edwards, G; Ilett, KF; Maggs, JL; Park, BK; Powell, SM | 1 |
| Xu, JH; Zhang, YP | 1 |
| de Vries, PJ; Ha, LD; Kager, PA; Khanh, NX; Koopmans, R; van Boxtel, CJ | 1 |
| Li, Y; Wu, YL | 1 |
| Le Bras, J | 1 |
| McLean, WG; Ward, SA | 1 |
| Looareesuwan, S; Wilairatana, P | 1 |
| Ding, Y; Qi, Z; Xu, C | 1 |
| Cheng-Qi, S; Mull, R; Qing, JX; van Agtmael, MA; van Boxtel, CJ | 1 |
| Karbwang, J; Na-Bangchang, K; Thanavibul, A; Tippawangkosol, P; Ubalee, R | 1 |
| Aguilar, AJ; Grace, JM; Skanchy, DJ | 1 |
| Basco, LK; Bickii, J; Ringwald, P | 1 |
| Eggelte, TA; van Agtmael, MA; van Boxtel, CJ; Vuong, TD | 1 |
| Edwards, G; Haynes, RK; Khalid, SA; Mohamed, SS; Tang, HP; Wan, TS; Ward, SA; Zheng, M | 1 |
| Chaovanakawee, S; Karbwang, J; Na-Bangchang, K; Saenglertsilapachai, S; Tippanangkosol, P; Ubalee, R | 1 |
| Gupta, V; van Agtmael, MA; van Boxtel, CJ; van der Graaf, CA | 1 |
| Duraisingh, MT; Jones, P; Pinder, M; Sambou, I; von Seidlein, L; Warhurst, DC | 1 |
| Karbwang, J; Na-Bangchang, K; Palacios, PA; Saengtertsilapachai, S; Ubalee, R; Wernsdorfer, WH | 1 |
| Karbwang, J; Le, NH; Le, TD; Na-Bangchang, K; Thrinh, KA | 1 |
| Chen, PQ; Fu, LC; Guo, XB; Jian, HX; Li, GQ; Wang, XH | 1 |
| Petavy, AF; Peyron, F; Saccharin, C; Sarciron, ME | 1 |
| Abdel Aziz, SS; el-Badawy, NM | 1 |
| Brewer, TG; Genovese, RF; Newman, DB | 1 |
| Batty, KT; Binh, TQ; Davis, TM; Hung, NC; Ilett, KF; Phuong, HL; Phuong, VD; Powell, SM; Thien, HV | 1 |
| Bishop, LP; Hindley, S; Maggs, JL; Miller, A; O'Neill, PM; Park, BK; Posner, GH; Roberts, SM; Scheinmann, F; Stachulski, AV; Ward, SA | 1 |
| Dodd, CC; Edwards, G; McLean, WG; Park, BK; Sadler, CJ; Smith, SL; Ward, SA | 1 |
| Maggs, JL; O'Neill, PM; Park, BK; Scheinmann, F; Stachulski, AV | 1 |
| Chen, L; Chen, PQ; Du, QY; Huang, ZY; Li, GQ; Wu, LN; Yang, DD; Yuan, J | 1 |
| Batty, KT; Binh, TQ; Davis, TM; Hung, NC; Ilett, KF; Phuöng, HL; Phuong, VD; Powell, SM; Thien, HV; Thu, LT | 1 |
| Bhisutthibhan, J; Meshnick, SR | 1 |
| Kollaritsch, H; Krudsood, S; Looareesuwan, S; Noedl, H; Wernsdorfer, WH; Wiedermann, G; Wilairatana, P | 1 |
| MacDonald, RD | 1 |
| Ashton, M; Davis, TM; Hai, TN; Huong, DX; Ilett, KF; Zhang, SQ | 1 |
| Tu, Y | 1 |
| Green, MD; Mount, DL; Wirtz, RA | 1 |
| Micha, ST; Wang, W; Yang, W | 1 |
| Brewer, TG; Eamsila, C; Jongsakul, K; Keeratithakul, G; Kyle, DE; Li, Q; Luesutthiviboon, L; Sirisopana, N; Teja-Isavadharm, P; Watt, G | 1 |
| Chen, Y; Ni, X | 1 |
| Batty, KT; Binh, TQ; Davis, TM; Hung, NC; Ilett, KF; Phuong, HL; Powell, SM; Thu, le TA | 1 |
| Looareesuwan, S; Newton, PN; Nosten, F; Rasameesoroj, M; Ruangveerayuth, R; Siriyanonda, D; Slight, T; Suputtamongkol, Y; Teerapong, P; Teja-Isavadharm, P; van Vugt, M; White, NJ | 1 |
| Gauducheau, N; Richard, F; Sandrenan, N; Souppart, C | 1 |
| Chen, P; Li, F; Tu, Y; Wang, F; Yang, L | 1 |
| Ketpirune, J; Siritanaratkul, N; Vattanaviboon, P; Wilairat, P; Yuthavong, Y | 1 |
| Batty, KT; Davis, TM; Iletr, KE; Martin, J; Powell, SM | 1 |
| Batty, KT; Binh, TQ; Burchell, B; Davis, TM; Edwards, G; Ethell, BT; Hung, NC; Ilett, KF; Maggs, JL; Park, BK; Pirmohamed, M; Thu, le TA | 1 |
| Davis, TM; Denis, MB; Fandeur, T; Hewitt, S; Incardona, S; Lim, C; Nimol, K; Poravuth, Y; Socheat, D | 1 |
| Agus, C; Batty, KT; Binh, TQ; Chiswell, GM; Davis, TM; Ilett, KF; Phuöng, HL; Phuong, VD | 1 |
| Mankhetkorn, S; Reungpatthanaphong, P | 1 |
| Chen, YG; Yu, BY | 1 |
| Lin, SG; Meng, F; Pang, XJ; Shen, H; Wang, SQ; Wen, Y; Zeng, LH; Zhu, QX; Zhuo, KR | 1 |
| Chen, C; Chen, PL; Chen, WJ; Feng, XP; Lin, SG; Liu, DQ; Liu, J; Wu, HM | 1 |
| Basilico, N; Haynes, RK; Monti, D; Olliaro, P; Parapini, S; Taramelli, D | 1 |
| Chalermrut, K; Krudsood, S; Looareesuwan, S; Pengruksa, C; Silachamroon, U; Srivilairit, S; Treeprasertsuk, S; Wilairatana, P | 1 |
| Buchachart, K; Chalermrut, K; Charusabha, C; Duangdee, C; Haoharn, O; Krudsood, S; Looareesuwan, S; Treeprasertsuk, S | 1 |
| Ayuo, P; Esamai, F; Guangqian, L; Ngindu, A; Obala, A; Ogaro, F; Owino-Ongor, W; Quoqiao, L; Rotich, J; Xingbo, G | 1 |
| Chen, HH; Fang, X; Zhou, HJ | 1 |
| Batty, KT; Davis, TM; Ilett, KF; Kotecka, BM; Rieckmann, KH | 1 |
| Gupta, RC; Madhusudanan, KP; Rajanikanth, M; Sabarinath, S | 1 |
| Brittenham, GM; Chalermrut, K; Kano, S; Krudsood, S; Looareesuwan, S; Pengruksa, C; Silachamroon, U; Srivilairit, S; Treeprasertsuk, S | 1 |
| Dong, YJ; Li, WD; Tu, YY | 1 |
| Graninger, W; Kremsner, PG; Noedl, H; Ramharter, M; Wernsdorfer, WH; Winkler, H; Winkler, S | 1 |
| Davis, TM; Denis, MB; Hung, TY; Ilett, KF; Karunajeewa, H; Lim, C; Socheat, D | 1 |
| Dolecek, C; Dong, TH; Farrar, J; Le, HT; Nguyen, TD; Nguyen, TT; Pham, PM; Stepniewska, K; Tran, TH; Tran, TT; White, NJ | 1 |
| Aarons, L; Edwards, G; Kokwaro, GO; Majid, O; Marsh, K; Mithwani, S; Mohamed, S; Muchohi, S; Watkins, W | 1 |
| Brewer, TG; Kyle, DE; Peggins, JO; Teja-Isavadharm, P; Webster, HK; White, NJ | 1 |
| Batty, KT; Davis, TM; Ilett, KF | 1 |
| Binh, TQ; de Vries, PJ; Giao, PT; Hung, le Q; Kager, PA; Nam, NV | 1 |
| Gabriëls, M; Plaizier-Vercammen, J | 1 |
| Kim, BJ; Sasaki, T | 1 |
| Ittarat, W; Pathepchotivong, K; Sreepian, A; Srisarin, A | 1 |
| Chen, HH; Wang, WQ; Wu, GD; Zhou, HJ | 1 |
| Alpers, MP; Barrett, PH; Bockarie, M; Davis, TM; Dufall, K; Ilett, KF; Karunajeewa, HA; Kemiki, A; Vicini, P | 1 |
| Hu, XS; Liao, L; Lu, DM; Lu, XJ; Ma, Y | 1 |
| Chan, HW; Croft, SL; Fugmann, B; Haynes, RK; Ho, WY; Peters, W; Robinson, BL; Stetter, J; Vivas, L | 1 |
| Ashley, EA; Brockman, A; Hutagalung, R; Krudsood, S; Leowattana, W; Looareesuwan, S; McGready, R; Nosten, F; Phaiphun, L; Srivilairit, S; White, NJ; Wilairatana, P | 1 |
| Adagu, IS; Fivelman, QL; Warhurst, DC | 2 |
| Kongthaisong, M; Mungthin, M; Na-Bangchang, K; Sinchaipanid, N; Tan-Ariya, P | 1 |
| Chalearmrult, K; Krudsood, S; Li, Q; Looareesuwan, S; Lugt, CB; Milhous, WK; Vannaphan, S; Wilairatana, P | 1 |
| Fleckenstein, L; Kirsch, LE; Murry, DJ; Naik, H | 1 |
| Chalermrut, K; Kano, S; Krudsood, S; Looareesuwan, S; Matangkasombut, O; Molunto, P; Na-Bangchang, K; Silachamroon, U; Tangpukdee, N; Tasanor, O | 1 |
| Diallo, TO; Doui-Doumgba, K; Flori, P; Garraud, O; Gbagba, FE; Nambei, WS; Ndadjimbaye, V; Ndémanga, J; Perraut, R | 1 |
| Karbwang, J; Na-Bangchang, K; Thanavibul, A; Tippawangkosol, P | 1 |
| Chanthap, L; Na-Bangchang, K; Nivanna, N; Socheat, D; Sovannarith, T; Suksom, D; Tsuyuoka, R | 1 |
| Gupta, RC; Madhusudanan, KP; Sabarinath, S | 1 |
| Brughera, M; Colombo, P; Gomes, M; Lansen, J; Longo, M; Manera, D; Mazué, G; Olliaro, P; Taylor, WR; Zanoncelli, S | 1 |
| Ashley, EA; Barends, M; Hutagalung, R; Looareesuwan, S; McGready, R; Nosten, F; Phaiphun, L; Proux, S; Slight, T; Thwai, KL; White, NJ | 1 |
| Kokwaro, G | 1 |
| Bangchang, KN; Chaijaroenkul, W; Mungthin, M; Ward, SA | 1 |
| Lee, J; Wu, XH; Zhou, HJ | 2 |
| Folb, PI; Smith, P; Waako, PJ | 1 |
| Kim, MS; Kim, SJ; Lee, CH; Lee, JW; Lee, SH; Park, MJ; Shin, SH; Yoo, H | 1 |
| Baege, AC; Centeno, JA; Disbrow, GL; Hartmann, D; Kierpiec, KA; Schlegel, R; Thibodeaux, CA; Yuan, H | 1 |
| D'Alessandro, U; Erhart, A; Karema, C; Mupfasoni, D; Rusanganwa, E; Rwagacondo, C; Tinto, H; Van Marck, E; Van Overmeir, C; Vandoren, W | 1 |
| Chalermrut, K; Kano, S; Krudsood, S; Looareesuwan, S; Pengruksa, C; Phongtananant, S; Silachamroon, U; Srivilairit, S; Tangpukdee, N; Thanachartwet, W; Wilairatana, P | 1 |
| Li, J; Zhou, HJ | 1 |
| Chaicharernwimonkoon, L; Chantaruk, S; Intereya, K; Isaka, M; Pakawatchai, C; Rukachaisirikul, V; Saithong, S; Tansakul, C | 1 |
| Cho, T; Gilveray, G; Looareesuwan, S; McGready, R; Nosten, F; Stepniewska, K; Ward, SA; White, NJ | 1 |
| Huang, S; Liu, YM; Lu, SQ; Tian, XF; Wang, FY | 1 |
| Ashton, M; Friberg Hietala, S; Hai, TN; Röshammar, D; Van Huong, N | 1 |
| Keiser, J; Shu-Hua, X; Tanner, M; Utzinger, J | 1 |
| Gao, P; Li, SH; Yan, PF; Yue, ZY; Zhang, JH | 1 |
| Bojang, K; Bruneton, C; Christophel, EM; Day, NP; Fernandez, F; Green, MD; Greenwood, BM; Kaur, H; Malenga, G; McGready, R; Millet, P; Newton, PN; Nosten, F; Palmer, K; Phanouvong, S; Proux, S; Singhasivanon, P; Sunjio, M; Talisuna, AO; White, NJ; Whitty, CJ | 1 |
| D'Alessandro, U; Fanello, CI; Karema, C; Ngamije, D; van Doren, W; van Geertruyden, JP; van Overmeir, C | 1 |
| Dong, YJ; Li, WD; Lin, ZB; Tu, YY | 1 |
| Duffy, PE; Mutabingwa, TK | 1 |
| Ashley, E; Aye, KZ; Barends, M; Htet, L; Kyaw, MK; Lindegardh, N; Lwin, S; Phe, O; Singtoroj, T; Smithuis, F; Stepniewska, K; White, NJ | 1 |
| Barends, M; Keola, S; Khanthavong, M; Lindegårdh, N; Mayxay, M; Newton, PN; Phetsouvanh, R; Phompida, S; Pongvongsa, T; Stepniewska, K; Thongpraseuth, V; White, NJ | 1 |
| Godin, B; Golenser, J; Touitou, E; Waknine, JH | 1 |
| Arvidsson, B; Ashton, M; Bergquist, J; Bergqvist, Y; Day, NP; Lindegårdh, N; Tarning, J; White, NJ | 1 |
| Brughera, M; Cocco, F; Colombo, P; Giusti, A; Gomes, M; Longo, M; Mazué, G; Navaratman, V; Olliaro, P; Pesenti, M; Riflettuto, M; Torre, PD; Zanoncelli, S | 1 |
| Ashley, EA; La, Y; Lindegardh, N; McGready, R; Nosten, F; Singhasivanon, P; Stepniewska, K; White, NJ | 1 |
| Barnes, KI; Chierakul, W; Evans, AC; Newton, PN; Ruangveerayuth, R; Smith, PJ; White, NJ | 1 |
| Agbenyega, T; Barnes, KI; Di Perri, G; Folb, P; Gomes, M; Krishna, S; Krudsood, S; Looareesuwan, S; Mansor, S; McIlleron, H; Miller, R; Molyneux, M; Mwenechanya, J; Navaratnam, V; Nosten, F; Olliaro, P; Pang, L; Ribeiro, I; Simpson, JA; Tembo, M; van Vugt, M; Ward, S; Weerasuriya, K; White, NJ; Win, K | 1 |
| Cambon, N; Davis, TM; Dunlop, AM; England, M; Heidecker, JL; Ilett, KF; Keller, TG; Page-Sharp, M | 1 |
| Atemnkeng, MA; De Cock, K; Plaizier-Vercammen, J | 1 |
| Ayede, I; Dada-Adegbola, HO; Fadero, FF; Falade, AG; Falade, CO; Gbotosho, GO; Happi, CT; Oduola, AM; Salako, LA | 1 |
| Wang, RL; Xing, J; Yan, HX; Zhang, LF; Zhang, SQ | 1 |
| Cojean, S; Durand, R; Hubert, V; Le Bras, J | 1 |
| Anderson, T; Barends, M; Brockman, A; Jaidee, A; Mayxay, M; Nair, S; Newton, PN; Phetsouvanh, R; Phompida, S; Pongvongsa, T; Sudimack, D; White, NJ | 1 |
| Ashley, EA; Brockman, A; Chan, S; Goubert, L; Janssens, B; Nong, S; Socheat, D; Uong, S; Van Damme, W; van Herp, M | 1 |
| Gosi, P; Limsomwong, C; Veerasubramanian, P; Walsh, DS | 1 |
| Anstey, NM; Ebsworth, EP; Kenangalem, E; Laihad, F; Maristela, R; Price, RN; Ratcliff, A; Siswantoro, H; Tjitra, E; Wuwung, RM | 1 |
| Anstey, NM; Ebsworth, EP; Hasugian, AR; Kenangalem, E; Laihad, F; Maristela, R; Penttinen, PM; Price, RN; Purba, HL; Tjitra, E; Wuwung, RM | 1 |
| Hung, le N; Hung, NC; Na-Bangchang, K; Thuy, le TD | 1 |
| Davis, TM; Ilett, KF; Karunajeewa, HA; Manning, L; Mueller, I | 1 |
| Huang, XJ; Ma, ZQ; Zhang, WP | 1 |
| Barrett, PH; Batty, KT; Davis, TM; Gibbons, PL; Ilett, KF | 1 |
| Chu, D; Fu, E; Jin, F; Liu, T; Mu, D; Xie, Y; Zhang, W | 1 |
| Chen, ZT; Gao, JF; Guo, Y; Wang, J; Zhang, BC | 1 |
| Huang, XJ; Lu, YB; Ma, ZQ; Wei, EQ; Zhang, WP | 1 |
| Chong, MT; Danh, PT; Diem Thuy, le T; Hung, le N; Na-Bangchang, K; Van Binh, N; Van Thang, N | 1 |
| Ashley, EA; Day, NP; Myint, HY; Nosten, F; White, NJ | 1 |
| Atipas, S; Chatsiricharoenkul, S; Kongpatanakul, S; Pongnarin, P; Sangvanich, P; Sathirakul, K; Suputtamongkol, Y; Watnasirichaikul, S | 1 |
| Lai, CS; Mansor, SM; Nair, NK; Navaratnam, V; Olliaro, PL | 1 |
| Ihongbe, JC; Isibor, J; Okodua, M; Otegbeye, T; Oviasogie, E; Tambo, E; Tatfeng, YM; Tchougang, S | 1 |
| Ashley, EA; Hae, R; La, Y; Mytton, OT; Nosten, F; Peto, L; Price, RN; Singhasivanon, P; White, NJ | 1 |
| Anstey, NM; Ebsworth, EP; Hasugian, AR; Kenangalem, E; Laihad, F; Lindegardh, N; Penttinen, P; Price, RN; Purba, HL; Ratcliff, A; Siswantoro, H; Tjitra, E | 1 |
| Amin, AA; Kokwaro, GO | 1 |
| Batty, KT; Law, AS; Moore, BR; Stirling, V | 1 |
| Basilico, N; D'Alessandro, S; Gelati, M; Haynes, RK; Parati, EA; Taramelli, D | 1 |
| Batty, KT; Davis, TM; Ilett, KF; Karunajeewa, HA; Lammey, J; Law, I; Lin, E; Mueller, I; Page-Sharp, M; Siba, P | 1 |
| Bernasconi, A; Casapia, M; D'Alessandro, U; Delgado, C; Erhart, A; Fanello, C; Gamboa, D; Grande, T; Llanos-Cuentas, A; Torres, K | 1 |
| Andrzejewski, C; Batty, KT; Ilett, KF; Jago, JD; Moore, BR; Page-Sharp, M | 1 |
| Batty, KT; Jago, JD; Moore, BR | 1 |
| Chaijaroenkul, W; Muhamad, P; Na-Bangchang, K; Pruktal, P | 1 |
| Chaudhary, S; Puri, SK; Singh, C | 1 |
| Dhooghe, L; Jansen, H; Pieters, L; Van Miert, S; Vlietinck, A | 1 |
| Felix, K; Fujise, K; Fujita, T; Hutadilok-Towatana, N; Liu, Z; Pinkaew, D | 1 |
| Cordonnier, JA; Jansen, FH; Soomro, SA; Van Quekelberghe, SA | 1 |
| Chavalitshewinkoon-Petmitr, P; Chingunpitak, J; Moribe, K; Puttipipatkhachorn, S; Tozuka, Y; Yamamoto, K | 1 |
| Couto, CG; Hosoya, K; Kisseberth, WC; Laio, A; London, CA; Murahari, S | 1 |
| Ansari, MT; Sunderland, VB | 1 |
| Li, A; Wang, Z; Zhou, HJ | 1 |
6 review(s) available for artenimol and sesquiterpenes
| Article | Year |
|---|---|
Studies of qinghaosu and its active derivatives in biological materials and their pharmacokinetics.
Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Sesquiterpenes; Structure-Activity Relationship | 1989 |
How Chinese scientists discovered qinghaosu (artemisinin) and developed its derivatives? What are the future perspectives?
Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Drug Evaluation; Drug Resistance; Forecasting; Humans; Malaria, Falciparum; Medicine, Chinese Traditional; Sesquiterpenes | 1998 |
The rational use of qinghaosu and its derivatives: what is the future of new compounds?
Topics: Administration, Oral; Administration, Rectal; Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Drug and Narcotic Control; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Registries; Sesquiterpenes; Suppositories; Thailand | 1998 |
Rectal administration of artemisinin derivatives for the treatment of malaria.
Topics: Administration, Rectal; Area Under Curve; Artemether; Artemisinins; Artesunate; Humans; Malaria; Sesquiterpenes | 2007 |
Efficacy and safety of dihydroartemisinin-piperaquine.
Topics: Antimalarials; Artemisinins; Asia, Southeastern; Drug Combinations; Female; Humans; Malaria, Falciparum; Male; Quinolines; Sesquiterpenes; Treatment Outcome | 2007 |
Antimalarial drug quality in Africa.
Topics: Africa; Antimalarials; Artemisinins; Biological Availability; Dosage Forms; Drug Combinations; Drug Stability; Drug Storage; Humans; Product Surveillance, Postmarketing; Pyrimethamine; Quality Control; Sesquiterpenes; Sulfadoxine | 2007 |
63 trial(s) available for artenimol and sesquiterpenes
| Article | Year |
|---|---|
Differential extraction of artemether and its metabolite dihydroartemisinin from plasma and determination by high-performance liquid chromatography.
Topics: Antimalarials; Artemether; Artemisinins; Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Indicators and Reagents; Sesquiterpenes; Spectrophotometry, Ultraviolet | 1994 |
[Randomised comparison on the treatment of falciparum malaria with dihydroartemisinin and piperaquine].
Topics: Adult; Antimalarials; Artemisinins; Drug Evaluation; Female; Humans; Malaria, Falciparum; Male; Quinolines; Sesquiterpenes | 1993 |
Pharmacokinetics of artemisinin and artesunate after oral administration in healthy volunteers.
Topics: Administration, Oral; Adult; Antimalarials; Area Under Curve; Artemisinins; Artesunate; Female; Half-Life; Humans; Male; Metabolic Clearance Rate; Middle Aged; Sesquiterpenes; Tablets | 1997 |
Single dose pharmacokinetics of oral artemether in healthy Malaysian volunteers.
Topics: Administration, Oral; Adult; Antimalarials; Artemether; Artemisinins; Blood Specimen Collection; Chromatography, High Pressure Liquid; Drug Stability; Humans; Malaysia; Male; Sesquiterpenes; Temperature | 1997 |
A pharmacokinetic and pharmacodynamic study of intravenous vs oral artesunate in uncomplicated falciparum malaria.
Topics: Administration, Oral; Adult; Antimalarials; Artemisinins; Artesunate; Female; Humans; Injections, Intravenous; Malaria, Falciparum; Male; Reference Values; Sesquiterpenes; Time Factors; Vietnam | 1998 |
Pharmacokinetics of oral artemether in Thai patients with uncomplicated falciparum malaria.
Topics: Administration, Oral; Adolescent; Adult; Antimalarials; Area Under Curve; Artemether; Artemisinins; Chromatography, High Pressure Liquid; Follow-Up Studies; Humans; Malaria, Falciparum; Sesquiterpenes; Thailand | 1998 |
Plasma concentrations of artemether and its major plasma metabolite, dihydroartemisinin, following a 5-day regimen of oral artemether, in patients with uncomplicated falciparum malaria.
Topics: Acute Disease; Adolescent; Adult; Antimalarials; Artemether; Artemisinins; Drug Resistance, Multiple; Follow-Up Studies; Humans; Malaria, Falciparum; Male; Middle Aged; Sesquiterpenes | 1998 |
Pharmacokinetics and ex vivo anti-malarial activity of sera following a single oral dose of dihydroartemisinin in healthy Thai males.
Topics: Adult; Antimalarials; Artemisinins; Drug Administration Schedule; Humans; Male; Reference Values; Sesquiterpenes; Thailand | 1997 |
Pharmacokinetics of intramuscular artemether in patients with severe falciparum malaria with or without acute renal failure.
Topics: Acute Kidney Injury; Adolescent; Adult; Antimalarials; Artemether; Artemisinins; Humans; Kidney; Malaria, Falciparum; Male; Metabolic Clearance Rate; Middle Aged; Sesquiterpenes; Treatment Outcome | 1998 |
Declining concentrations of dihydroartemisinin in plasma during 5-day oral treatment with artesunate for Falciparum malaria.
Topics: Adult; Antimalarials; Artemisinins; Artesunate; Chromatography, High Pressure Liquid; Electrochemistry; Humans; Malaria, Falciparum; Male; Sesquiterpenes | 1999 |
Multiple dose pharmacokinetics of artemether in Chinese patients with uncomplicated falciparum malaria.
Topics: Adolescent; Adult; Antimalarials; Artemether; Artemisinins; China; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Lumefantrine; Malaria, Falciparum; Male; Middle Aged; Models, Chemical; Sesquiterpenes; Time Factors | 1999 |
Pharmacokinetic and pharmacodynamic interactions of mefloquine and dihydroartemisinin.
Topics: Administration, Oral; Adult; Animals; Antimalarials; Artemisinins; Chromatography, High Pressure Liquid; Cross-Over Studies; Drug Interactions; Drug Synergism; Humans; Male; Mefloquine; Models, Statistical; Plasmodium falciparum; Sesquiterpenes | 1999 |
Comparative clinical trial of four regimens of dihydroartemisinin-mefloquine in multidrug-resistant falciparum malaria.
Topics: Administration, Oral; Adolescent; Adult; Antimalarials; Artemisinins; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance, Multiple; Drug Therapy, Combination; Humans; Malaria, Falciparum; Male; Mefloquine; Sesquiterpenes; Treatment Outcome | 1999 |
The effect of grapefruit juice on the time-dependent decline of artemether plasma levels in healthy subjects.
Topics: Administration, Oral; Adult; Antifungal Agents; Antimalarials; Antiprotozoal Agents; Artemether; Artemisinins; Beverages; Biological Availability; Citrus; Cross-Over Studies; Food-Drug Interactions; Humans; Male; Reference Values; Sesquiterpenes; Time Factors | 1999 |
Pharmacokinetics and bioequivalence evaluation of three commercial tablet formulations of mefloquine when given in combination with dihydroartemisinin in patients with acute uncomplicated falciparum malaria.
Topics: Acute Disease; Adolescent; Adult; Antimalarials; Artemisinins; Biological Availability; Chromatography, High Pressure Liquid; Drug Therapy, Combination; Humans; Malaria, Falciparum; Male; Mefloquine; Recurrence; Sesquiterpenes; Tablets; Thailand; Therapeutic Equivalency; Time Factors | 2000 |
Phamacokinetics of a single oral dose of dihydroartemisinin in Vietnamese healthy volunteers.
Topics: Administration, Oral; Adult; Antimalarials; Artemisinins; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Male; Sesquiterpenes; Time Factors; Vietnam | 1999 |
Dose findings of dihydroartemisinin in treatment of falciparum malaria.
Topics: Administration, Oral; Adolescent; Adult; Aged; Antimalarials; Artemisinins; Child; China; Dose-Response Relationship, Drug; Drug Resistance; Fever; Follow-Up Studies; Humans; Malaria, Falciparum; Middle Aged; Sesquiterpenes; Time Factors | 1999 |
Pharmacokinetics and pharmacodynamics of intravenous artesunate in severe falciparum malaria.
Topics: Adult; Antimalarials; Area Under Curve; Artemisinins; Artesunate; Female; Half-Life; Humans; Infusions, Intravenous; Malaria, Falciparum; Male; Sesquiterpenes | 2001 |
Oral bioavailability of dihydroartemisinin in Vietnamese volunteers and in patients with falciparum malaria.
Topics: Administration, Oral; Adult; Antimalarials; Artemisinins; Biological Availability; Cross-Over Studies; Dose-Response Relationship, Drug; Half-Life; Humans; Injections, Intravenous; Malaria, Falciparum; Metabolic Clearance Rate; Sesquiterpenes; Time Factors; Vietnam | 2001 |
Multiple dose study of interactions between artesunate and artemisinin in healthy volunteers.
Topics: Administration, Oral; Adult; Antimalarials; Area Under Curve; Artemisinins; Artesunate; Chromatography, High Pressure Liquid; Drug Administration Schedule; Drug Interactions; Half-Life; Humans; Linear Models; Male; Metabolic Clearance Rate; Sesquiterpenes | 2001 |
Efficacy of dihydroartemisinin-mefloquine on acute uncomplicated falciparum malaria.
Topics: Acute Disease; Adolescent; Adult; Animals; Antimalarials; Artemisinins; Child; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Nausea; Plasmodium falciparum; Sesquiterpenes; Treatment Outcome; Vomiting | 2001 |
The pharmacokinetic properties of intramuscular artesunate and rectal dihydroartemisinin in uncomplicated falciparum malaria.
Topics: Administration, Rectal; Adult; Antimalarials; Area Under Curve; Artemisinins; Artesunate; Confidence Intervals; Cross-Over Studies; Female; Humans; Injections, Intramuscular; Injections, Intravenous; Malaria, Falciparum; Male; Sesquiterpenes; Statistics, Nonparametric | 2002 |
Comparison of oral artesunate and dihydroartemisinin antimalarial bioavailabilities in acute falciparum malaria.
Topics: Acute Disease; Adolescent; Adult; Aged; Antimalarials; Area Under Curve; Artemisinins; Artesunate; Biological Availability; Chromatography, High Pressure Liquid; Cross-Over Studies; Double-Blind Method; Female; Half-Life; Humans; Malaria, Falciparum; Male; Middle Aged; Sesquiterpenes; Spectrophotometry, Ultraviolet; Vietnam | 2002 |
Relative bioavailability of artesunate and dihydroartemisinin: investigations in the isolated perfused rat liver and in healthy Caucasian volunteers.
Topics: Administration, Oral; Adult; Animals; Antimalarials; Area Under Curve; Artemisinins; Artesunate; Biological Availability; Dose-Response Relationship, Drug; Female; Humans; Liver; Male; Rats; Rats, Wistar; Reference Values; Sesquiterpenes | 2002 |
Efficacy and safety of dihydroartemisinin-piperaquine (Artekin) in Cambodian children and adults with uncomplicated falciparum malaria.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Cambodia; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Falciparum; Male; Quinolines; Sesquiterpenes; Treatment Outcome | 2002 |
Penetration of dihydroartemisinin into cerebrospinal fluid after administration of intravenous artesunate in severe falciparum malaria.
Topics: Adolescent; Adult; Artemisinins; Artesunate; Chromatography, High Pressure Liquid; Female; Half-Life; Humans; Injections, Intravenous; Malaria, Cerebral; Malaria, Falciparum; Male; Middle Aged; Sesquiterpenes | 2003 |
[Study on treatment of multi-drug resistant falciparum malaria by using a combination of dihydroartemisinin and pyronaridine].
Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Child; Child, Preschool; Double-Blind Method; Drug Resistance, Multiple; Drug Therapy, Combination; Humans; Infant; Malaria, Falciparum; Middle Aged; Naphthyridines; Sesquiterpenes | 2002 |
An open randomized clinical trial of Artecom vs artesunate-mefloquine in the treatment of acute uncomplicated falciparum malaria in Thailand.
Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Artesunate; Child; Drug Combinations; Drug Resistance, Multiple; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Quinolines; Sesquiterpenes; Thailand; Trimethoprim | 2002 |
A comparative clinical trial of combinations of dihydroartemisinin plus azithromycin and dihydroartemisinin plus mefloquine for treatment of multidrug resistant falciparum malaria.
Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Azithromycin; Drug Combinations; Drug Resistance, Multiple; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Sesquiterpenes; Statistics, Nonparametric; Thailand | 2002 |
Rectal dihydroartemisinin versus intravenous quinine in the treatment of severe malaria: a randomised clinical trial.
Topics: Administration, Rectal; Adolescent; Adult; Antimalarials; Artemisinins; Child; Child, Preschool; Humans; Infusions, Intravenous; Malaria, Falciparum; Middle Aged; Quinine; Sesquiterpenes | 2000 |
Comparative clinical trial of two-fixed combinations dihydroartemisinin-napthoquine-trimethoprim (DNP) and artemether-lumefantrine (Coartem/Riamet) in the treatment of acute uncomplicated falciparum malaria in Thailand.
Topics: Adolescent; Adult; Antimalarials; Artemether; Artemisinins; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Lumefantrine; Malaria, Falciparum; Male; Middle Aged; Sesquiterpenes; Thailand; Treatment Outcome; Trimethoprim | 2003 |
Safety evaluation of fixed combination piperaquine plus dihydroartemisinin (Artekin) in Cambodian children and adults with malaria.
Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Blood Glucose; Cambodia; Child; Child, Preschool; Drug Combinations; Drug Evaluation; Electrocardiography; Heart Rate; Hematocrit; Humans; Infant; Infant, Newborn; Malaria, Falciparum; Malaria, Vivax; Middle Aged; Quinolines; Sesquiterpenes | 2004 |
Dihydroartemisinin-piperaquine against multidrug-resistant Plasmodium falciparum malaria in Vietnam: randomised clinical trial.
Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Child; Child, Preschool; Drug Combinations; Drug Resistance, Multiple; Female; Follow-Up Studies; Humans; Malaria, Falciparum; Male; Pilot Projects; Plasmodium falciparum; Quinolines; Sesquiterpenes; Treatment Outcome; Trimethoprim; Vietnam | 2004 |
CV8, a new combination of dihydroartemisinin, piperaquine, trimethoprim and primaquine, compared with atovaquone-proguanil against falciparum malaria in Vietnam.
Topics: Adolescent; Adult; Aged; Animals; Antimalarials; Artemisinins; Atovaquone; Drug Combinations; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Naphthoquinones; Parasitemia; Plasmodium falciparum; Primaquine; Proguanil; Quinolines; Sesquiterpenes; Treatment Outcome; Trimethoprim; Vietnam | 2004 |
Disposition of artesunate and dihydroartemisinin after administration of artesunate suppositories in children from Papua New Guinea with uncomplicated malaria.
Topics: Aging; alpha-Thalassemia; Antimalarials; Artemisinins; Artesunate; Body Weight; Child; Chromatography, High Pressure Liquid; Female; Genotype; Half-Life; Humans; Malaria; Male; Models, Statistical; Papua New Guinea; Population; Sesquiterpenes; Sex Characteristics; Spectrometry, Mass, Electrospray Ionization; Suppositories; Tissue Distribution | 2004 |
Randomized, controlled dose-optimization studies of dihydroartemisinin-piperaquine for the treatment of uncomplicated multidrug-resistant falciparum malaria in Thailand.
Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Drug Combinations; Drug Resistance, Multiple; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Plasmodium falciparum; Quinolines; Sesquiterpenes; Thailand | 2004 |
Comparison of the bioequivalence of three oral formulations of dihydroartemisinin based on ex vivo blood schizontocidal activities against Plasmodium falciparum.
Topics: Administration, Oral; Adult; Animals; Antimalarials; Area Under Curve; Artemisinins; Cells, Cultured; Chemistry, Pharmaceutical; Cross-Over Studies; Humans; Malaria, Falciparum; Male; Parasitemia; Plasmodium falciparum; Sesquiterpenes; Therapeutic Equivalency | 2004 |
Pharmacokinetic investigation on the therapeutic potential of artemotil (beta-arteether) in Thai patients with severe Plasmodium falciparum malaria.
Topics: Adult; Antimalarials; Area Under Curve; Artemisinins; Half-Life; Humans; Injections, Intramuscular; Malaria, Falciparum; Sesquiterpenes | 2004 |
The pharmacokinetics of oral dihydroartemisinin and artesunate in healthy Thai volunteers.
Topics: Administration, Oral; Adult; Antimalarials; Area Under Curve; Artemisinins; Artesunate; Biological Availability; Cross-Over Studies; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Sesquiterpenes; Thailand | 2004 |
Efficacy comparison between anti-malarial drugs in Africans presenting with mild malaria in the Central Republic of Africa: a preliminary study.
Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Central African Republic; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Parasitemia; Parasitic Sensitivity Tests; Patient Compliance; Plasmodium falciparum; Pyrimethamine; Quinine; Quinolines; Sesquiterpenes; Sulfadoxine; Treatment Outcome; Trimethoprim | 2005 |
Pharmacokinetics of the four combination regimens of dihydroartemisinin/mefloquine in acute uncomplicated falciparum malaria.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Animals; Antimalarials; Artemisinins; Drug Therapy, Combination; Humans; Malaria, Falciparum; Mefloquine; Sesquiterpenes | 2005 |
Investigation of bioavailability, pharmacokinetics and safety of new pediatric formulations of artesunate and mefloquine.
Topics: Administration, Oral; Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Biological Availability; Drug Therapy, Combination; Humans; Malaria; Male; Mefloquine; Pediatrics; Sesquiterpenes | 2005 |
A randomized, controlled study of a simple, once-daily regimen of dihydroartemisinin-piperaquine for the treatment of uncomplicated, multidrug-resistant falciparum malaria.
Topics: Adolescent; Adult; Aged; Animals; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Drug Combinations; Drug Resistance, Multiple; Female; Humans; Infant; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Plasmodium falciparum; Quinolines; Sesquiterpenes | 2005 |
An open randomized clinical trial of Artekin vs artesunate-mefloquine in the treatment of acute uncomplicated falciparum malaria.
Topics: Acute Disease; Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Drug Combinations; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Quinolines; Sesquiterpenes; Thailand; Treatment Outcome | 2005 |
Pharmacokinetics of piperaquine after repeated oral administration of the antimalarial combination CV8 in 12 healthy male subjects.
Topics: Administration, Oral; Adult; Antimalarials; Artemisinins; Chromatography, High Pressure Liquid; Drug Combinations; Fasting; Half-Life; Humans; Male; Middle Aged; Pilot Projects; Primaquine; Quinolines; Sesquiterpenes; Trimethoprim | 2006 |
Safety and efficacy of dihydroartemisinin/piperaquine (Artekin) for the treatment of uncomplicated Plasmodium falciparum malaria in Rwandan children.
Topics: Antimalarials; Artemisinins; Child, Preschool; Drug Combinations; Female; Humans; Leukocyte Count; Malaria, Falciparum; Male; Quinolines; Rwanda; Sesquiterpenes; Treatment Outcome | 2006 |
Efficacy and effectiveness of dihydroartemisinin-piperaquine versus artesunate-mefloquine in falciparum malaria: an open-label randomised comparison.
Topics: Adolescent; Animals; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Falciparum; Male; Mefloquine; Myanmar; Plasmodium falciparum; Quinolines; Recurrence; Sesquiterpenes; Treatment Outcome | 2006 |
An open, randomized comparison of artesunate plus mefloquine vs. dihydroartemisinin-piperaquine for the treatment of uncomplicated Plasmodium falciparum malaria in the Lao People's Democratic Republic (Laos).
Topics: Administration, Oral; Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Child; Drug Therapy, Combination; Female; Humans; Laos; Malaria, Falciparum; Male; Mefloquine; Parasitemia; Quinolines; Recurrence; Sesquiterpenes; Treatment Failure; Treatment Outcome | 2006 |
Characterization of human urinary metabolites of the antimalarial piperaquine.
Topics: Antimalarials; Artemisinins; Chromatography, Liquid; Drug Combinations; Humans; Magnetic Resonance Spectroscopy; Male; Quinolines; Sesquiterpenes; Tandem Mass Spectrometry | 2006 |
The pharmacokinetics of artemether and lumefantrine in pregnant women with uncomplicated falciparum malaria.
Topics: Adolescent; Adult; Antimalarials; Area Under Curve; Artemether; Artemisinins; Drug Administration Schedule; Ethanolamines; Female; Fluorenes; Follow-Up Studies; Half-Life; Humans; Lumefantrine; Malaria, Falciparum; Male; Pregnancy; Pregnancy Outcome; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Recurrence; Remission Induction; Sesquiterpenes; Tablets; Thailand | 2006 |
The pharmacokinetics of intravenous artesunate in adults with severe falciparum malaria.
Topics: Administration, Oral; Adolescent; Adult; Age Factors; Antimalarials; Area Under Curve; Artemisinins; Artesunate; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electrochemistry; Female; Half-Life; Humans; Injections, Intravenous; Malaria, Falciparum; Male; Metabolic Clearance Rate; Middle Aged; Pilot Projects; Quinine; Sesquiterpenes; Severity of Illness Index; Thailand | 2006 |
Dihydroartemisinin suppository in moderately severe malaria: comparative efficacy of dihydroartemisinin suppository versus intramuscular artemeter followed by oral sulfadoxine-pyrimethamine in the management of moderately severe malaria in Nigerian childr
Topics: Antimalarials; Artemether; Artemisinins; Child; Child, Preschool; Drug Combinations; Humans; Infant; Injections, Intramuscular; Malaria, Falciparum; Nigeria; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Suppositories | 2007 |
A randomized open study to assess the efficacy and tolerability of dihydroartemisinin-piperaquine for the treatment of uncomplicated falciparum malaria in Cambodia.
Topics: Adolescent; Adult; Aged; Anemia; Antimalarials; Artemisinins; Artesunate; Cambodia; Child; Child, Preschool; Drug Therapy, Combination; Female; Genome, Protozoan; Humans; Infant; Malaria, Falciparum; Malaria, Vivax; Male; Mefloquine; Middle Aged; Quinolines; Recurrence; Sesquiterpenes; Treatment Outcome | 2007 |
Two fixed-dose artemisinin combinations for drug-resistant falciparum and vivax malaria in Papua, Indonesia: an open-label randomised comparison.
Topics: Adolescent; Adult; Anemia; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Child, Preschool; Diarrhea; Drug Administration Schedule; Drug Combinations; Drug Resistance, Multiple; Ethanolamines; Female; Fluorenes; Humans; Indonesia; Infant; Malaria, Falciparum; Malaria, Vivax; Male; Middle Aged; Prospective Studies; Quinolines; Recurrence; Sesquiterpenes; Treatment Outcome; Urticaria; Vomiting | 2007 |
Dihydroartemisinin-piperaquine versus artesunate-amodiaquine: superior efficacy and posttreatment prophylaxis against multidrug-resistant Plasmodium falciparum and Plasmodium vivax malaria.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Artesunate; Drug Resistance, Multiple; Drug Tolerance; Humans; Indonesia; Malaria, Falciparum; Malaria, Vivax; Plasmodium falciparum; Quinolines; Sesquiterpenes; Treatment Outcome | 2007 |
Pharmacokinetics of mefloquine with dihydroartemisinin as 2-day regimens in patients with uncomplicated falciparum malaria.
Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Drug Administration Schedule; Drug Therapy, Combination; Humans; Interviews as Topic; Malaria, Falciparum; Male; Mefloquine; Plasmodium falciparum; Sesquiterpenes; Treatment Outcome | 2007 |
Clinical efficacy of high dose monotherapy of oral dihydroartemisinin in uncomplicated falciparum malaria in viet nam.
Topics: Administration, Oral; Adolescent; Adult; Animals; Antimalarials; Artemisinins; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Plasmodium falciparum; Sesquiterpenes; Treatment Outcome; Vietnam | 2007 |
Evaluation of the safety and relative bioavailability of a new dihydroartemisinin tablet formulation in healthy Thai volunteers.
Topics: Administration, Oral; Adult; Antimalarials; Artemisinins; Biological Availability; Cross-Over Studies; Female; Humans; Male; Sesquiterpenes; Tablets; Thailand; Treatment Outcome | 2007 |
An analytical method with a single extraction procedure and two separate high performance liquid chromatographic systems for the determination of artesunate, dihydroartemisinin and mefloquine in human plasma for application in clinical pharmacological stu
Topics: Administration, Oral; Adult; Antimalarials; Artemisinins; Artesunate; Chemistry Techniques, Analytical; Chromatography, High Pressure Liquid; Drug Combinations; Drug Stability; Female; Freezing; Humans; Male; Mefloquine; Reproducibility of Results; Sesquiterpenes; Time Factors | 2007 |
Electrocardiographic safety evaluation of dihydroartemisinin piperaquine in the treatment of uncomplicated falciparum malaria.
Topics: Arrhythmias, Cardiac; Artemisinins; Electrocardiography; Humans; Malaria, Falciparum; Sesquiterpenes | 2007 |
Clinical and pharmacological determinants of the therapeutic response to dihydroartemisinin-piperaquine for drug-resistant malaria.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; Child, Preschool; Drug Administration Schedule; Female; Humans; Indonesia; Infant; Malaria; Male; Middle Aged; Prospective Studies; Quinolines; Sesquiterpenes; Survival Analysis; Treatment Outcome | 2007 |
Pharmacokinetics and efficacy of piperaquine and chloroquine in Melanesian children with uncomplicated malaria.
Topics: Animals; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Malaria, Vivax; Male; Papua New Guinea; Plasmodium falciparum; Plasmodium vivax; Pyrimethamine; Quinolines; Sesquiterpenes; Sulfadoxine; Treatment Outcome | 2008 |
A randomised controlled trial to assess the efficacy of dihydroartemisinin-piperaquine for the treatment of uncomplicated falciparum malaria in Peru.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Peru; Quinolines; Sesquiterpenes | 2007 |
171 other study(ies) available for artenimol and sesquiterpenes
| Article | Year |
|---|---|
Hepatic metabolism of artemisinin drugs--III. Induction of hydrogen peroxide production in rat liver microsomes by artemisinin drugs.
Topics: Animals; Antimalarials; Artemisinins; Hydrogen Peroxide; Kinetics; Male; Microsomes, Liver; NADP; Rats; Rats, Inbred Strains; Sesquiterpenes | 1992 |
Selective determination, in plasma, of artemether and its major metabolite, dihydroartemisinin, by high-performance liquid chromatography with ultraviolet detection.
Topics: Artemether; Artemisinins; Chromatography, High Pressure Liquid; Humans; Schistosomicides; Sesquiterpenes; Spectrophotometry, Ultraviolet | 1992 |
Hemin-catalyzed decomposition of artemisinin (qinghaosu).
Topics: Antimalarials; Artemisinins; Dose-Response Relationship, Drug; Ferric Compounds; Hemin; Oxidation-Reduction; Sesquiterpenes | 1992 |
Antimalarial activity of new dihydroartemisinin derivatives. 5. Sugar analogues.
Topics: Animals; Antimalarials; Artemisinins; Carbohydrates; Mice; Plasmodium berghei; Plasmodium falciparum; Sesquiterpenes | 1992 |
Hepatic metabolism of artemisinin drugs--I. Drug metabolism in rat liver microsomes.
Topics: Animals; Antimalarials; Artemisinins; Chromatography, High Pressure Liquid; Chromatography, Liquid; Kinetics; Liver; Male; Mass Spectrometry; Microsomes, Liver; Rats; Rats, Inbred Strains; Sesquiterpenes | 1991 |
[Pharmacokinetics and metabolism of artesunate in cows].
Topics: Animals; Artemisinins; Artesunate; Cattle; Chromatography, Thin Layer; Female; Sesquiterpenes | 1991 |
Determination of the antimalarial arteether and its deethylated metabolite dihydroartemisinin in plasma by high-performance liquid chromatography with reductive electrochemical detection.
Topics: Animals; Antimalarials; Artemisinins; Biological Availability; Chromatography, High Pressure Liquid; Dogs; Electrochemistry; Oxidation-Reduction; Reproducibility of Results; Sesquiterpenes | 1991 |
Effects of artemisinin, dihydroartemisinin and arteether on immune responses of normal mice.
Topics: Animals; Antibody Formation; Antimalarials; Artemisinins; Carrageenan; Hemolytic Plaque Technique; Hypersensitivity, Delayed; Immunosuppressive Agents; Inflammation; Male; Mice; Sesquiterpenes | 1990 |
[The pharmacokinetics of dihydroqinghasu given orally to rabbits and dogs].
Topics: Administration, Oral; Animals; Artemisinins; Dogs; Rabbits; Radioimmunoassay; Sesquiterpenes; Tablets | 1990 |
Antimalarial activity of new water-soluble dihydroartemisinin derivatives. 2. Stereospecificity of the ether side chain.
Topics: Animals; Artemisinins; Chemical Phenomena; Chemistry; Malaria; Mice; Molecular Structure; Plasmodium falciparum; Sesquiterpenes; Solubility; Stereoisomerism; Structure-Activity Relationship; Water | 1989 |
[Pharmacodynamics of dihydroartemisinine against Plasmodium berghei in mice].
Topics: Animals; Antimalarials; Artemisinins; Dose-Response Relationship, Drug; Malaria; Male; Mice; Plasmodium berghei; Sesquiterpenes; Time Factors | 1989 |
Hemolysis induced by artemisinin and its derivatives in vitro.
Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Erythrocytes; Hemoglobins; Hemolysis; Humans; Pyrans; Sesquiterpenes | 1986 |
[Studies on mutarotation and anomeric conversion of dihydroqinghaosu].
Topics: Artemisinins; Chromatography, High Pressure Liquid; Sesquiterpenes; Stereoisomerism | 1988 |
The chemotherapy of rodent malaria, XL. The action of artemisinin and related sesquiterpenes.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Drug Resistance; Malaria; Male; Mice; Pigments, Biological; Plasmodium berghei; Pyrans; Sesquiterpenes | 1986 |
Determination of dihydroqinghaosu in blood by pyrolysis gas chromatography/mass spectrometry.
Topics: Animals; Artemisinins; Gas Chromatography-Mass Spectrometry; Male; Rabbits; Sesquiterpenes | 1988 |
[A preliminary study on the urinary excretion of artesunate and its metabolites in man after a single intravenous injection].
Topics: Adult; Antimalarials; Artemisinins; Artesunate; Chromatography, High Pressure Liquid; Half-Life; Humans; Injections, Intravenous; Male; Sesquiterpenes | 1987 |
Analysis of artesunic acid and dihydroqinghaosu in blood by high-performance liquid chromatography with reductive electrochemical detection.
Topics: Animals; Artemisinins; Artesunate; Chromatography, High Pressure Liquid; Drug Stability; Electrochemistry; Humans; Hydrolysis; Kinetics; Rabbits; Rats; Rats, Inbred Strains; Sesquiterpenes | 1987 |
In vitro sensitivity of Naegleria fowleri to qinghaosu and dihydroqinghaosu.
Topics: Amoeba; Amphotericin B; Animals; Artemisinins; Sesquiterpenes | 1987 |
Antimalarial activity of new water-soluble dihydroartemisinin derivatives.
Topics: Animals; Antimalarials; Artemisinins; Drug Stability; Mice; Sesquiterpenes; Solubility; Structure-Activity Relationship | 1987 |
[Studies on analogs of qinghaosu (artean-nuin, artemisinine). III. The synthesis of diacid esters and mono esters of dihydroqinghaosu].
Topics: Animals; Antimalarials; Artemisinins; Esters; Plasmodium berghei; Sesquiterpenes | 1985 |
The chemotherapy of rodent malaria, XXXIX. Ultrastructural changes following treatment with artemisinine of Plasmodium berghei infection in mice, with observations of the localization of [3H]-dihydroartemisinine in P. falciparum in vitro.
Topics: Animals; Antimalarials; Artemisinins; Cell Membrane; Endoplasmic Reticulum; Erythrocytes; Malaria; Mice; Microscopy, Electron; Plasmodium berghei; Plasmodium falciparum; Protein Biosynthesis; Ribosomes; Sesquiterpenes; Time Factors | 1985 |
[Studies on analogs of qinghaosu. VII. The synthesis of ethers of bis(dihydroqinghaosu) and bis(dihydrodeoxyqinghaosu)].
Topics: Antimalarials; Artemisinins; Ethers; Plasmodium berghei; Sesquiterpenes; Structure-Activity Relationship | 1985 |
[Studies on analogs of qinghaosu (artemisinine, arteannuin). IV. Synthesis of derivatives of qinghaosu containing halogen, nitrogen and sulfur heteroatoms].
Topics: Animals; Antimalarials; Artemisinins; Mice; Sesquiterpenes | 1985 |
[Determination of artesunate and dihydroqinghaosu in human plasma by high performance liquid chromatography with a reductive mode electrochemical detection].
Topics: Antimalarials; Artemisinins; Artesunate; Chromatography, High Pressure Liquid; Humans; Sesquiterpenes | 1985 |
[Studies on the fate of artesunate by GC-MS, HPLC and TLCS methods].
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cytochrome P-450 Enzyme System; Dogs; Gas Chromatography-Mass Spectrometry; Male; Mice; Microsomes, Liver; Rabbits; Rats; Sesquiterpenes | 1985 |
Rapid action of Qinghaosu and related drugs on incorporation of [3H]isoleucine by Plasmodium falciparum in vitro.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Isoleucine; Kinetics; Plasmodium falciparum; Protein Biosynthesis; Pyrans; Sesquiterpenes; Tritium | 1983 |
Effects of qinghaosu and related compounds on incorporation of [G-3H] hypoxanthine by Plasmodium falciparum in vitro.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Hypoxanthine; Hypoxanthines; Plasmodium falciparum; Pyrans; Sesquiterpenes; Time Factors | 1983 |
Uptake of [3H] dihydroartemisinine by erythrocytes infected with Plasmodium falciparum in vitro.
Topics: Anisomycin; Antimalarials; Artemether; Artemisinins; Chloroquine; Erythrocytes; Humans; Plasmodium falciparum; Pyrans; Sesquiterpenes | 1984 |
Determination of artesunate and dihydroartemisinine in plasma by liquid chromatography with post-column derivatization and UV-detection.
Topics: Antimalarials; Artemisinins; Artesunate; Chromatography, Liquid; Humans; Sesquiterpenes; Spectrophotometry, Ultraviolet | 1984 |
Determination of artemether and dihydroartemisinin in blood plasma by high-performance liquid chromatography for application in clinical pharmacological studies.
Topics: Adult; Antimalarials; Artemether; Artemisinins; Chromatography, High Pressure Liquid; Electrochemistry; Humans; Isomerism; Male; Reference Values; Reproducibility of Results; Sesquiterpenes | 1995 |
Enhancement of interleukin-2 production and its mRNA expression by dihydroartemisinin.
Topics: Animals; Antimalarials; Artemisinins; Cell Division; Cell Line; Female; Gene Expression; Interleukin-2; Lymphocyte Activation; Mice; Mice, Inbred BALB C; RNA, Messenger; Sesquiterpenes; Spleen | 1994 |
Selective cancer cell cytotoxicity from exposure to dihydroartemisinin and holotransferrin.
Topics: Artemisinins; Cell Survival; Dose-Response Relationship, Drug; Drug Combinations; Humans; Lymphocytes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sesquiterpenes; Time Factors; Transferrin; Tumor Cells, Cultured | 1995 |
Synthesis, characterization, and antimalarial activity of the glucuronides of the hydroxylated metabolites of arteether.
Topics: Animals; Antimalarials; Artemisinins; Chromatography, High Pressure Liquid; Glucuronates; Hydrolysis; Hydroxylation; Microbial Sensitivity Tests; Models, Chemical; Plasmodium falciparum; Sesquiterpenes; Stereoisomerism | 1995 |
Antimalarial activity of new dihydroartemisinin derivatives. 6. alpha-Alkylbenzylic ethers.
Topics: Animals; Antimalarials; Artemisinins; In Vitro Techniques; Plasmodium falciparum; Sesquiterpenes; Stereoisomerism; Structure-Activity Relationship | 1995 |
Reaction of antimalarial endoperoxides with specific parasite proteins.
Topics: Animals; Antimalarials; Artemisinins; Autoradiography; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Erythrocytes; Plasmodium falciparum; Protozoan Proteins; Sesquiterpenes; Styrenes | 1994 |
Antimalarial activity of dihydroartemisinin derivatives by transdermal application.
Topics: Administration, Cutaneous; Animals; Antimalarials; Artemether; Artemisinins; Gels; Malaria; Mice; Plasmodium berghei; Sesquiterpenes; Structure-Activity Relationship | 1994 |
Clinical trials of artemisinin and its derivatives in the treatment of malaria in China.
Topics: Antimalarials; Antiprotozoal Agents; Artemisinins; Artesunate; China; Clinical Trials as Topic; Humans; Injections, Intramuscular; Injections, Intravenous; Malaria, Cerebral; Malaria, Falciparum; Sesquiterpenes; Suppositories; Tablets | 1994 |
Comparison of in vivo and in vitro antimalarial activity of artemisinin, dihydroartemisinin and sodium artesunate in the Plasmodium berghei-rodent model.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Malaria; Mice; Plasmodium berghei; Rats; Rats, Wistar; Sesquiterpenes | 1994 |
Ferriprotoporphyrin catalysed decomposition of artemether: analytical and pharmacological implications.
Topics: Antimalarials; Artemether; Artemisinins; Carbon Radioisotopes; Catalysis; Chromatography, High Pressure Liquid; Hemin; Hemoglobins; Hemolysis; Humans; In Vitro Techniques; Sesquiterpenes; Spectrophotometry, Ultraviolet | 1994 |
The interaction of artemisinin with red cell membranes.
Topics: Antimalarials; Artemisinins; Autoradiography; Electrophoresis, Polyacrylamide Gel; Erythrocyte Membrane; Erythrocytes; Humans; Phospholipases A; Phospholipases A2; Sesquiterpenes | 1994 |
Pharmacokinetics of artemether after oral administration to healthy Thai males and patients with acute, uncomplicated falciparum malaria.
Topics: Administration, Oral; Adult; Animals; Antimalarials; Artemether; Artemisinins; Humans; Malaria, Falciparum; Male; Plasmodium falciparum; Sesquiterpenes; Thailand | 1994 |
[Pharmacokinetics of dihydroqinghaosu in human volunteers and comparison with qinghaosu].
Topics: Administration, Oral; Adult; Artemisinins; Biological Availability; Estrenes; Humans; Male; Radioimmunoassay; Sesquiterpenes; Suppositories; Tablets | 1993 |
Decomposition of arteether in simulated stomach acid yielding compounds retaining antimalarial activity.
Topics: Animals; Antimalarials; Artemisinins; Chromatography, High Pressure Liquid; Gastric Acid; Half-Life; Magnetic Resonance Spectroscopy; Plasmodium falciparum; Sesquiterpenes | 1993 |
Artemisinin and its derivatives enhance T lymphocyte-mediated immune responses in normal mice and accelerate immunoreconstitution of mice with syngeneic bone marrow transplantation.
Topics: Adjuvants, Immunologic; Analysis of Variance; Animals; Antimalarials; Artemisinins; Artesunate; B-Lymphocytes; Bone Marrow Transplantation; Concanavalin A; DNA; Dose-Response Relationship, Immunologic; Female; Hypersensitivity, Delayed; Immunity, Cellular; Interleukin-2; Lipopolysaccharides; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Sesquiterpenes; Spleen; T-Lymphocytes | 1993 |
Oral administration of dihydroartemisinin and ferrous sulfate retarded implanted fibrosarcoma growth in the rat.
Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Artemisinins; Female; Ferrous Compounds; Fibrosarcoma; Neoplasm Transplantation; Rats; Rats, Inbred F344; Reactive Oxygen Species; Sesquiterpenes | 1995 |
Structure-activity relationships of the antimalarial agent artemisinin. 2. Effect of heteroatom substitution at O-11: synthesis and bioassay of N-alkyl-11-aza-9-desmethylartemisinins.
Topics: Animals; Antimalarials; Artemisinins; Drug Evaluation, Preclinical; Drugs, Chinese Herbal; Erythrocytes; Humans; Molecular Structure; Plasmodium falciparum; Sesquiterpenes; Structure-Activity Relationship | 1995 |
Selective high-performance liquid chromatographic determination of artesunate and alpha- and beta-dihydroartemisinin in patients with falciparum malaria.
Topics: Antimalarials; Artemisinins; Artesunate; Chromatography, High Pressure Liquid; Humans; Isomerism; Malaria, Falciparum; Reproducibility of Results; Sesquiterpenes; Spectrophotometry, Ultraviolet | 1996 |
Chemical stability of artesunate injection and proposal for its administration by intravenous infusion.
Topics: Antimalarials; Artemisinins; Artesunate; Chromatography, High Pressure Liquid; Drug Stability; Drug Storage; Half-Life; Infusions, Intravenous; Injections, Intravenous; Reference Standards; Sesquiterpenes; Sodium Chloride; Statistics as Topic; Syringes; Temperature | 1996 |
Treatment of acute, uncomplicated, falciparum malaria with oral dihydroartemisinin.
Topics: Acute Disease; Adolescent; Adult; Antimalarials; Artemisinins; Drug Resistance, Multiple; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Parasitemia; Sesquiterpenes; Thailand; Treatment Outcome | 1996 |
In vitro stage-specific sensitivity of Plasmodium falciparum to quinine and artemisinin drugs.
Topics: Adult; Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Drug Evaluation, Preclinical; Drug Resistance; Humans; In Vitro Techniques; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Quinine; Sesquiterpenes | 1996 |
Artemisinin neurotoxicity: neuropathology in rats and mechanistic studies in vitro.
Topics: Alkylation; Animals; Antimalarials; Artemisinins; Blood Proteins; Brain; Detergents; Erythrocytes; Male; Mice; Molecular Weight; Nerve Tissue Proteins; Neuroblastoma; Neurons; Octoxynol; Plasmodium falciparum; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Tumor Cells, Cultured | 1997 |
In vitro susceptibility of Plasmodium falciparum isolates in Vietnam to artemisinin derivatives and other antimalarials.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Mefloquine; Microbial Sensitivity Tests; Plasmodium falciparum; Quinine; Sesquiterpenes; Vietnam | 1997 |
Determination of artemether and its major metabolite, dihydroartemisinin, in plasma using high-performance liquid chromatography with electrochemical detection.
Topics: Adult; Antimalarials; Artemether; Artemisinins; Chromatography, High Pressure Liquid; Electrochemistry; Humans; Isomerism; Male; Sensitivity and Specificity; Sesquiterpenes | 1997 |
Antimalarial activity of new dihydroartemisinin derivatives. 7. 4-(p-substituted phenyl)-4(R or S)-[10(alpha or beta)-dihydroartemisininoxy]butyric acids.
Topics: Animals; Antimalarials; Artemisinins; Drug Design; Female; Magnetic Resonance Spectroscopy; Malaria; Mice; Molecular Conformation; Molecular Structure; Parasitemia; Plasmodium berghei; Plasmodium falciparum; Sesquiterpenes; Solubility | 1997 |
Determination of artemether and its metabolite, dihydroartemisinin, in plasma by high-performance liquid chromatography and electrochemical detection in the reductive mode.
Topics: Acetates; Acetonitriles; Antimalarials; Artemether; Artemisinins; Autoanalysis; Chromatography, High Pressure Liquid; Drug Stability; Humans; Quality Control; Sensitivity and Specificity; Sesquiterpenes | 1997 |
Simultaneous determination of artesunic acid and dihydroartemisinin in blood plasma by high-performance liquid chromatography for application in clinical pharmacological studies.
Topics: Adult; Antimalarials; Artemisinins; Artesunate; Chromatography, High Pressure Liquid; Humans; Male; Reproducibility of Results; Sensitivity and Specificity; Sesquiterpenes | 1997 |
The rat biliary metabolites of dihydroartemisinin, an antimalarial endoperoxide.
Topics: Animals; Antimalarials; Artemisinins; Bile; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Male; Mass Spectrometry; Rats; Rats, Wistar; Sesquiterpenes | 1997 |
Effects of Plasmodium berghei infection on arteether metabolism and disposition.
Topics: Animals; Antimalarials; Area Under Curve; Artemisinins; Bile; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Half-Life; Isotope Labeling; Liver; Malaria; Male; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Perfusion; Plasmodium berghei; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Tissue Distribution | 1997 |
Validation of an improved reversed-phase high-performance liquid chromatography assay with reductive electrochemical detection for the determination of artemisinin derivatives in man.
Topics: Antimalarials; Artemisinins; Chromatography, High Pressure Liquid; Electrochemistry; Humans; Sesquiterpenes | 1998 |
Binding of dihydroartemisinin to hemoglobin H: role in drug accumulation and host-induced antimalarial ineffectiveness of alpha-thalassemic erythrocytes.
Topics: alpha-Thalassemia; Animals; Antimalarials; Artemisinins; Erythrocytes; Hemoglobin H; Plasmodium falciparum; Sesquiterpenes | 1998 |
Pharmacokinetic and bioequivalence evaluation of two generic formulations of oral artesunate.
Topics: Administration, Oral; Adult; Animals; Antimalarials; Artemisinins; Artesunate; Drugs, Generic; Humans; Malaria, Falciparum; Male; Plasmodium falciparum; Sesquiterpenes; Therapeutic Equivalency | 1998 |
The pharmacokinetics and bioavailability of dihydroartemisinin, arteether, artemether, artesunic acid and artelinic acid in rats.
Topics: Absorption; Animals; Antimalarials; Area Under Curve; Artemether; Artemisinins; Biological Availability; Bridged Bicyclo Compounds, Heterocyclic; Male; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Succinates | 1998 |
Metabolism of beta-arteether to dihydroqinghaosu by human liver microsomes and recombinant cytochrome P450.
Topics: Antimalarials; Artemisinins; Cytochrome P-450 Enzyme System; Humans; Microsomes, Liver; Sesquiterpenes | 1998 |
Selection and characterization of Toxoplasma gondii mutants resistant to artemisinin.
Topics: Animals; Antimalarials; Antiprotozoal Agents; Artemether; Artemisinins; Drug Resistance; Ethyl Methanesulfonate; Female; Humans; Methylnitronitrosoguanidine; Mice; Mice, Inbred ICR; Mutagenesis; Sesquiterpenes; Toxoplasma; Toxoplasmosis, Animal | 1998 |
Plasma levels of artesunate and dihydroartemisinin in children with Plasmodium falciparum malaria in Gabon after administration of 50-milligram artesunate suppositories.
Topics: Absorption; Antimalarials; Artemisinins; Artesunate; Child; Female; Fever; Gabon; Humans; Malaria, Falciparum; Male; Parasitemia; Sesquiterpenes; Suppositories | 1998 |
In vitro sensitivity of Plasmodium falciparum to eight antimalarials in China-Myanmar and China-Lao PDR border areas.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Artesunate; China; Chloroquine; Drug Evaluation, Preclinical; Drug Resistance; Humans; Laos; Microbial Sensitivity Tests; Myanmar; Naphthyridines; Plasmodium falciparum; Quinine; Sesquiterpenes | 1997 |
Morphological and immunocytochemical effects of dihydroartemisinin on differentiating NB2a neuroblastoma cells.
Topics: Animals; Antimalarials; Artemisinins; Blotting, Western; Cell Differentiation; Cytoskeletal Proteins; Fluorescent Antibody Technique; Mice; Microscopy, Electron; Microscopy, Electron, Scanning; Microtubule Proteins; Nerve Tissue Proteins; Neuroblastoma; Neurofilament Proteins; Neurons; Sesquiterpenes; Spectrin | 1998 |
Binding of dihydroartemisinin to differentiating neuroblastoma cells and rat cortical homogenate.
Topics: Animals; Antimalarials; Artemisinins; Cell Differentiation; Cerebral Cortex; Glioma; Hemin; Indicators and Reagents; Male; Nerve Tissue Proteins; Neuroblastoma; Neurons; Protein Binding; Radioligand Assay; Rats; Rats, Wistar; Sesquiterpenes; Tumor Cells, Cultured | 1998 |
The Plasmodium falciparum translationally controlled tumor protein homolog and its reaction with the antimalarial drug artemisinin.
Topics: Amino Acid Sequence; Animals; Antimalarials; Artemisinins; Biomarkers, Tumor; Calcium-Binding Proteins; Cloning, Molecular; Drugs, Chinese Herbal; Erythrocytes; Humans; Models, Chemical; Molecular Sequence Data; Plasmodium falciparum; Protein Binding; Recombinant Proteins; Sequence Alignment; Sesquiterpenes; Tumor Protein, Translationally-Controlled 1 | 1998 |
Simple high-performance liquid chromatographic method with electrochemical detection for the simultaneous determination of artesunate and dihydroartemisinin in biological fluids.
Topics: Adult; Antimalarials; Artemisinins; Artesunate; Chromatography, High Pressure Liquid; Electrochemistry; Humans; Male; Sensitivity and Specificity; Sesquiterpenes | 1998 |
Comparative pharmacokinetic study of oral and rectal formulations of artesunic acid in healthy volunteers.
Topics: Administration, Oral; Administration, Rectal; Adult; Antimalarials; Artemisinins; Bridged Bicyclo Compounds, Heterocyclic; Cross-Over Studies; Humans; Male; Sesquiterpenes; Succinates | 1998 |
A comparison of three different dihydroartemisinin formulations for the treatment of acute uncomplicated falciparum malaria in Thailand.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Animals; Antimalarials; Artemisia; Artemisinins; Chemistry, Pharmaceutical; Drug Evaluation; Female; Follow-Up Studies; Humans; Malaria, Falciparum; Male; Middle Aged; Phytotherapy; Plants, Medicinal; Sesquiterpenes; Thailand; Time Factors; Treatment Outcome | 1998 |
Synthesis and antimalarial activities of fluoroalkyl derivatives of dihydroartemisinin.
Topics: Animals; Antimalarials; Artemisinins; Drug Evaluation, Preclinical; Female; Inhibitory Concentration 50; Malaria; Mice; Plasmodium berghei; Plasmodium falciparum; Sesquiterpenes; Structure-Activity Relationship | 1998 |
Assessment of the effect of malaria infection on hepatic clearance of dihydroartemisinin using rat liver perfusions and microsomes.
Topics: Animals; Antimalarials; Artemisinins; Biliary Tract; Glucuronates; Malaria; Male; Metabolic Clearance Rate; Microsomes, Liver; Perfusion; Rats; Rats, Wistar; Sesquiterpenes | 1998 |
[Contragestational effects of dihydroartemisinin and artesunate].
Topics: Abortifacient Agents, Nonsteroidal; Animals; Artemisinins; Artesunate; Contraceptive Agents, Female; Cricetinae; Embryo Loss; Female; Guinea Pigs; Mice; Mice, Inbred ICR; Pregnancy; Rabbits; Sesquiterpenes; Uterus | 1996 |
In vitro susceptibility of African Plasmodium falciparum isolates to dihydroartemisinin and the risk factors for resistance to qinghaosu.
Topics: Africa; Animals; Antimalarials; Artemisinins; Chloroquine; Cross Reactions; Drug Evaluation, Preclinical; Drug Resistance; France; Humans; Malaria, Falciparum; Mefloquine; Phenanthrenes; Plasmodium falciparum; Sesquiterpenes; Travel | 1998 |
In vitro neurotoxicity of artemisinin derivatives.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Cell Differentiation; Central Nervous System Diseases; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Mice; Microscopy, Electron; Neuroblastoma; Neurons; Reproducibility of Results; Sesquiterpenes; Tumor Cells, Cultured | 1998 |
[Efficacy of dihydroartemisinin in treatment of 37 malaria cases].
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; Female; Humans; Malaria, Falciparum; Malaria, Vivax; Male; Middle Aged; Recurrence; Sesquiterpenes | 1997 |
Metabolism of artelinic acid to dihydroqinqhaosu by human liver cytochrome P4503A.
Topics: Adult; Aged; Antifungal Agents; Antimalarials; Artemisinins; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Combinations; Drug Interactions; Drugs, Chinese Herbal; Enzyme Inhibitors; Female; Glycyrrhiza; Humans; Inactivation, Metabolic; Inhibitory Concentration 50; Isoenzymes; Ketoconazole; Liver; Male; Miconazole; Microsomes, Liver; Middle Aged; Oxidoreductases, N-Demethylating; Paeonia; Quinidine; Recombinant Proteins; Sesquiterpenes; Sulfaphenazole; Troleandomycin; Vasodilator Agents; Verapamil | 1999 |
In vitro activity of dihydroartemisinin against clinical isolates of Plasmodium falciparum in Yaounde, Cameroon.
Topics: Animals; Antimalarials; Artemisinins; Cameroon; Humans; Inhibitory Concentration 50; Plasmodium falciparum; Sesquiterpenes | 1999 |
The development of an immunoassay for the detection of artemisinin compounds in urine.
Topics: Adult; Antibodies, Monoclonal; Antimalarials; Artemisinins; Artesunate; Cross Reactions; Enzyme-Linked Immunosorbent Assay; Humans; Sesquiterpenes | 1999 |
Simultaneous determination of artemether and its major metabolite dihydroartemisinin in plasma by gas chromatography-mass spectrometry-selected ion monitoring.
Topics: Adult; Antimalarials; Artemether; Artemisinins; Calibration; Gas Chromatography-Mass Spectrometry; Humans; Male; Reference Standards; Reference Values; Reproducibility of Results; Sensitivity and Specificity; Sesquiterpenes | 1999 |
Inoculum effect leads to overestimation of in vitro resistance for artemisinin derivatives and standard antimalarials: a Gambian field study.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Gambia; Hematocrit; Humans; Malaria, Falciparum; Mefloquine; Parasitemia; Phenanthrenes; Plasmodium falciparum; Quinine; Scintillation Counting; Sensitivity and Specificity; Sesquiterpenes | 1999 |
Effects of artesunate, dihydroartemisinin, and an artesunate-dihydroartemisinin combination against Toxoplasma gondii.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Brain; Cell Line; Cell Survival; Drug Combinations; Female; Histocytochemistry; Humans; Mice; Sesquiterpenes; Toxoplasma; Toxoplasmosis, Animal | 2000 |
Experimental trials of an artemisinin derivative in treatment of Schistosoma mansoni infected mice.
Topics: Animals; Anthelmintics; Artemisinins; Mice; Praziquantel; Schistosomiasis mansoni; Sesquiterpenes | 2000 |
Behavioral and neural toxicity of the artemisinin antimalarial, arteether, but not artesunate and artelinate, in rats.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Behavior, Animal; Brain; Brain Stem; Discrimination Learning; Male; Rats; Rats, Sprague-Dawley; Sesquiterpenes | 2000 |
Synthesis, antimalarial activity, biomimetic iron(II) chemistry, and in vivo metabolism of novel, potent C-10-phenoxy derivatives of dihydroartemisinin.
Topics: Animals; Antimalarials; Artemisinins; Bile; Crystallography, X-Ray; Electron Spin Resonance Spectroscopy; Ferrous Compounds; Free Radicals; Malaria; Male; Mice; Phenyl Ethers; Plasmodium berghei; Plasmodium falciparum; Plasmodium yoelii; Rats; Rats, Wistar; Sesquiterpenes; Stereoisomerism; Structure-Activity Relationship | 2001 |
The role of glutathione in the neurotoxicity of artemisinin derivatives in vitro.
Topics: Animals; Antimalarials; Antimetabolites; Antioxidants; Artemether; Artemisinins; Buthionine Sulfoximine; Drug Interactions; Glutathione; Hemin; Humans; Mice; Neurites; Sesquiterpenes; Tumor Cells, Cultured | 2001 |
Efficient preparations of the beta-glucuronides of dihydroartemisinin and structural confirmation of the human glucuronide metabolite.
Topics: Antimalarials; Artemisinins; Chromatography, Liquid; Glucuronides; Humans; Malaria, Falciparum; Male; Mass Spectrometry; Sesquiterpenes; Stereoisomerism | 2001 |
Effects of dihydroartemisinin on fine structure of erythrocytic stages of Plasmodium berghei ANKA strain.
Topics: Animals; Antimalarials; Artemisinins; Erythrocytes; Mice; Microscopy, Electron; Plasmodium berghei; Sesquiterpenes | 2000 |
Immunoprecipitation of [(3)H]dihydroartemisinin translationally controlled tumor protein (TCTP) adducts from Plasmodium falciparum-infected erythrocytes by using anti-TCTP antibodies.
Topics: Animals; Antibodies, Protozoan; Antimalarials; Artemisinins; Biomarkers, Tumor; Calcium-Binding Proteins; Erythrocytes; Plasmodium falciparum; Precipitin Tests; Protein Binding; Protozoan Proteins; Sesquiterpenes; Tumor Protein, Translationally-Controlled 1 | 2001 |
Antimalarial activity of azithromycin, artemisinin and dihydroartemisinin in fresh isolates of Plasmodium falciparum in Thailand.
Topics: Animals; Anti-Bacterial Agents; Antimalarials; Artemisinins; Azithromycin; Dose-Response Relationship, Drug; Humans; Parasitic Sensitivity Tests; Plasmodium falciparum; Sesquiterpenes; Thailand | 2001 |
Ammunition against malaria.
Topics: Antimalarials; Artemether; Artemisinins; Canada; Humans; Malaria; Sesquiterpenes | 2001 |
The development of new antimalarial drugs: qinghaosu and dihydro-qinghaosu.
Topics: Animals; Antimalarials; Artemether; Artemisia; Artemisinins; Artesunate; Drugs, Chinese Herbal; Humans; Sesquiterpenes | 1999 |
Authentication of artemether, artesunate and dihydroartemisinin antimalarial tablets using a simple colorimetric method.
Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Colorimetry; Diazonium Compounds; Sesquiterpenes; Tablets | 2001 |
Selective toxicity of dihydroartemisinin and holotransferrin toward human breast cancer cells.
Topics: Antimalarials; Antineoplastic Agents; Artemisinins; Breast; Breast Neoplasms; Cell Survival; Drug Combinations; Female; Humans; Sesquiterpenes; Transferrin; Tumor Cells, Cultured; X-Rays | 2001 |
Comparative pharmacokinetics and effect kinetics of orally administered artesunate in healthy volunteers and patients with uncomplicated falciparum malaria.
Topics: Administration, Oral; Adult; Antimalarials; Area Under Curve; Artemisinins; Artesunate; Chromatography, High Pressure Liquid; Humans; Malaria, Falciparum; Male; Sesquiterpenes | 2001 |
[In vitro study of the anti-pneumocystis carinii effect of arteminsin derivatives].
Topics: Animals; Artemisinins; Artesunate; Cell Division; Dose-Response Relationship, Drug; Humans; Pneumocystis; Rats; Rats, Wistar; Sesquiterpenes; Time Factors; Tumor Cells, Cultured | 2001 |
Development and validation of a high-performance liquid chromatography-mass spectrometry assay for the determination of artemether and its metabolite dihydroartemisinin in human plasma.
Topics: Antimalarials; Artemether; Artemisinins; Calibration; Chromatography, High Pressure Liquid; Humans; Mass Spectrometry; Reproducibility of Results; Sensitivity and Specificity; Sesquiterpenes | 2002 |
[Effect of dihydroquinghaosu on the development of Plasmodium yoelii yoelii in Anopheles stephensi].
Topics: Animals; Anopheles; Antimalarials; Artemisinins; Malaria; Mice; Plasmodium yoelii; Sesquiterpenes | 1998 |
Membrane heme as a host factor in reducing effectiveness of dihydroartemisinin.
Topics: alpha-Thalassemia; Artemisinins; Contraceptive Agents, Female; Erythrocyte Membrane; Erythrocytes; Ferrozine; Heme; Hemoglobins; Humans; Iron; Oxidative Stress; Protein Denaturation; Sesquiterpenes | 2002 |
Glucuronidation of dihydroartemisinin in vivo and by human liver microsomes and expressed UDP-glucuronosyltransferases.
Topics: Adult; Antimalarials; Artemisinins; Artesunate; Female; Glucuronides; Glucuronosyltransferase; Humans; In Vitro Techniques; Malaria, Falciparum; Male; Microsomes, Liver; Recombinant Proteins; Sesquiterpenes | 2002 |
Modulation of multidrug resistance by artemisinin, artesunate and dihydroartemisinin in K562/adr and GLC4/adr resistant cell lines.
Topics: Artemisinins; Artesunate; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line; Drug Resistance, Multiple; Humans; K562 Cells; Membrane Potentials; Mitochondria; Multidrug Resistance-Associated Proteins; Sesquiterpenes; Tumor Cells, Cultured | 2002 |
[Pharmacokinetic studies on artemether under conditions simulated in vivo].
Topics: Artemether; Artemisinins; Biological Availability; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Patient Simulation; Sesquiterpenes | 2002 |
[Therapeutic effect of dihydroartemisinin combined with naphthoquine phosphate in patients with falciparum malaria].
Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Child; Child, Preschool; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Malaria, Falciparum; Male; Middle Aged; Sesquiterpenes; Treatment Outcome | 2002 |
Artemisinin antimalarials do not inhibit hemozoin formation.
Topics: Antimalarials; Artemisinins; Heme; Hemeproteins; Hemin; Sesquiterpenes | 2003 |
Inhibition of human cancer cell line growth and human umbilical vein endothelial cell angiogenesis by artemisinin derivatives in vitro.
Topics: Angiogenesis Inhibitors; Artemisinins; Artesunate; Cell Culture Techniques; Cell Line, Tumor; Dose-Response Relationship, Drug; Endothelium, Vascular; Growth Inhibitors; Humans; Neovascularization, Pathologic; Sesquiterpenes; Umbilical Veins | 2003 |
Comparison of bioassay and high performance liquid chromatographic assay of artesunate and dihydroartemisinin in plasma.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Biological Assay; Chromatography, High Pressure Liquid; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Plasmodium falciparum; Sesquiterpenes | 2003 |
A sensitive and selective liquid chromatographic/electrospray ionization tandem mass spectrometric assay for the simultaneous quantification of alpha-,beta-arteether and its metabolite dihydroartemisinin in plasma, useful for pharmacokinetic studies.
Topics: Antimalarials; Artemisinins; Chromatography, High Pressure Liquid; Sensitivity and Specificity; Sesquiterpenes; Spectrometry, Mass, Electrospray Ionization | 2003 |
WHO to support production of indigenous antimalarial medicine in Africa.
Topics: Antimalarials; Artemisinins; Costs and Cost Analysis; Humans; Sesquiterpenes; Tanzania; World Health Organization | 2003 |
[Effect of dihydro-qinghaosu on auto-antibody production, TNF alpha secretion and pathologic change of lupus nephritis in BXSB mice].
Topics: Animals; Antibodies, Antinuclear; Artemisinins; Immunosuppressive Agents; Lupus Erythematosus, Systemic; Lupus Nephritis; Male; Mice; Mice, Inbred Strains; Random Allocation; Sesquiterpenes; Tumor Necrosis Factor-alpha | 2003 |
In vitro activity and interaction of clindamycin combined with dihydroartemisinin against Plasmodium falciparum.
Topics: Animals; Anti-Bacterial Agents; Antimalarials; Artemisinins; Clindamycin; Drug Combinations; Drug Resistance; Drug Synergism; Humans; Malaria, Falciparum; Plasmodium falciparum; Sesquiterpenes | 2003 |
Population pharmacokinetics of artemether and dihydroartemisinin following single intramuscular dosing of artemether in African children with severe falciparum malaria.
Topics: Acidosis, Respiratory; Antimalarials; Artemether; Artemisinins; Child; Child, Preschool; Female; Half-Life; Humans; Infant; Injections, Intramuscular; Malaria, Falciparum; Male; Respiratory Insufficiency; Sesquiterpenes | 2004 |
Plasmodium falciparum-based bioassay for measurement of artemisinin derivatives in plasma or serum.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Biological Assay; Biotransformation; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Electrochemistry; Hot Temperature; Humans; In Vitro Techniques; Macaca mulatta; Malaria, Falciparum; Plasmodium falciparum; Reproducibility of Results; Sesquiterpenes | 2004 |
Protein binding and alpha : beta anomer ratio of dihydroartemisinin in vivo.
Topics: Adult; Albumins; Antimalarials; Artemisinins; Female; Humans; Malaria, Falciparum; Male; Protein Binding; Sesquiterpenes | 2004 |
Design of a dissolution system for the evaluation of the release rate characteristics of artemether and dihydroartemisinin from tablets.
Topics: Artemether; Artemisinins; Calibration; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; Rotation; Sesquiterpenes; Solubility; Solvents; Tablets | 2004 |
Synthesis of O-aminodihydroartemisinin via TMS triflate catalyzed C-O coupling reaction.
Topics: Amines; Artemisinins; Benzaldehydes; Catalysis; Glycosylation; Hydroxylation; Mesylates; Molecular Structure; Oximes; Sesquiterpenes; Trimethylsilyl Compounds | 2004 |
Effect of dihydroartemisinin on the antioxidant capacity of P. falciparum-infected erythrocytes.
Topics: Animals; Antimalarials; Antioxidants; Artemisinins; Erythrocytes; Glutathione Peroxidase; Humans; In Vitro Techniques; Oxidative Stress; Plasmodium falciparum; Sesquiterpenes; Survival Analysis | 2003 |
Antimalarial dihydroartemisinin also inhibits angiogenesis.
Topics: Angiogenesis Inhibitors; Animals; Antimalarials; Artemisinins; Cell Division; Cells, Cultured; Chick Embryo; Flow Cytometry; Humans; In Situ Nick-End Labeling; Microscopy, Fluorescence; Receptors, Vascular Endothelial Growth Factor; Sesquiterpenes; Vascular Endothelial Growth Factor A | 2004 |
Activity of dihydroartemisinin against Leishmania donovani both in vitro and vivo.
Topics: Animals; Artemisinins; Cricetinae; Leishmania donovani; Male; Mesocricetus; Sesquiterpenes | 2004 |
Highly antimalaria-active artemisinin derivatives: biological activity does not correlate with chemical reactivity.
Topics: Animals; Antimalarials; Artemisinins; Free Radicals; Mice; Molecular Conformation; Parasitic Sensitivity Tests; Sesquiterpenes; Structure-Activity Relationship | 2004 |
Modified fixed-ratio isobologram method for studying in vitro interactions between atovaquone and proguanil or dihydroartemisinin against drug-resistant strains of Plasmodium falciparum.
Topics: Animals; Antimalarials; Artemisinins; Atovaquone; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Drug Resistance; Drug Synergism; Naphthoquinones; Plasmodium falciparum; Proguanil; Reproducibility of Results; Sesquiterpenes | 2004 |
Development and validation of a high-performance liquid chromatography-mass spectroscopy assay for determination of artesunate and dihydroartemisinin in human plasma.
Topics: Antimalarials; Artemisinins; Artesunate; Chromatography, High Pressure Liquid; Drug Stability; Freezing; Humans; Mass Spectrometry; Reproducibility of Results; Sesquiterpenes | 2005 |
Pharmacokinetics of the diastereomers of arteether, a potent antimalarial drug, in rats.
Topics: Administration, Oral; Animals; Antimalarials; Area Under Curve; Artemisinins; Injections, Intramuscular; Injections, Intravenous; Male; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Stereoisomerism | 2005 |
Effects of the antimalarial drug dihydroartemisinin (DHA) on rat embryos in vitro.
Topics: Animals; Antimalarials; Artemisinins; Embryonic Development; Erythrocytes; In Vitro Techniques; Rats; Sesquiterpenes | 2006 |
Once-daily combination therapy for uncomplicated malaria: is this the way forward?
Topics: Animals; Antimalarials; Artemisinins; Drug Combinations; Drug Resistance, Multiple; Humans; Malaria, Falciparum; Plasmodium falciparum; Quinolines; Sesquiterpenes | 2005 |
In vitro antimalarial drug susceptibility in Thai border areas from 1998-2003.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Quinine; Sesquiterpenes; Thailand; Time Factors | 2005 |
Dihydroartemisinin downregulates vascular endothelial growth factor expression and induces apoptosis in chronic myeloid leukemia K562 cells.
Topics: Antimalarials; Apoptosis; Artemisinins; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Sesquiterpenes; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A | 2006 |
In vitro interactions of Aspilia africana (Pers.) C.D. Adams, a traditional antimalarial medicinal plant, with artemisinin against Plasmodium falciparum.
Topics: Animals; Antimalarials; Artemisinins; Asteraceae; Drug Interactions; Erythrocytes; India; Medicine, Traditional; Plant Extracts; Plasmodium falciparum; Sesquiterpenes | 2005 |
Dihydroartemisinin enhances radiosensitivity of human glioma cells in vitro.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Acetylcysteine; Antimalarials; Artemisinins; Blotting, Western; Cell Line, Tumor; Dose-Response Relationship, Drug; Gamma Rays; Glioma; Glutathione Transferase; Humans; Radiation-Sensitizing Agents; Reactive Oxygen Species; Sesquiterpenes; Transferrin; Tumor Stem Cell Assay | 2006 |
Dihydroartemisinin is cytotoxic to papillomavirus-expressing epithelial cells in vitro and in vivo.
Topics: Animals; Apoptosis; Artemisinins; Dogs; Epithelial Cells; Female; HeLa Cells; Humans; Mitochondria; Mouth Mucosa; Papillomaviridae; Papillomavirus Infections; Reactive Oxygen Species; Sesquiterpenes; Uterine Cervical Neoplasms; Virus Replication | 2005 |
In-vitro susceptibility of Plasmodium falciparum to monodesethylamodiaquine, dihydroartemisinin and quinine in an area of high chloroquine resistance in Rwanda.
Topics: Adolescent; Adult; Amodiaquine; Animals; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Resistance, Multiple; Female; Humans; Infant; Inhibitory Concentration 50; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Quinine; Rwanda; Sesquiterpenes | 2006 |
[Dihydroartemisinin inhibits the expression of vascular endothelial growth factor in K562 cells].
Topics: Animals; Antineoplastic Agents, Phytogenic; Artemisinins; Cell Proliferation; Chickens; Chorioallantoic Membrane; Dose-Response Relationship, Drug; Down-Regulation; Humans; K562 Cells; Neovascularization, Pathologic; RNA, Messenger; Sesquiterpenes; Vascular Endothelial Growth Factor A | 2005 |
A cyclopeptide from the Insect pathogenic fungus Cordyceps sp. BCC 1788.
Topics: Animals; Antimalarials; Artemisinins; Chlorocebus aethiops; Chromatography, High Pressure Liquid; Coleoptera; Cordyceps; Crystallography, X-Ray; Inhibitory Concentration 50; Larva; Molecular Structure; Peptides, Cyclic; Plasmodium falciparum; Protein Conformation; Sesquiterpenes; Thailand; Vero Cells | 2006 |
Pharmacokinetics of dihydroartemisinin following oral artesunate treatment of pregnant women with acute uncomplicated falciparum malaria.
Topics: Acute Disease; Adolescent; Adult; Analysis of Variance; Antimalarials; Artemisinins; Artesunate; Atovaquone; Drug Combinations; Drug Resistance, Multiple; Drug Therapy, Combination; Female; Half-Life; Humans; Malaria, Falciparum; Pregnancy; Pregnancy Complications, Parasitic; Pregnancy Outcome; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Proguanil; Sesquiterpenes; Thailand | 2006 |
[Effect of dihydroartemisinin on ultrastructure of Giardia lamblia in vitro].
Topics: Animals; Antimalarials; Artemisinins; Dose-Response Relationship, Drug; Giardia lamblia; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Sesquiterpenes | 2005 |
Artesunate and artemether are effective fasciolicides in the rat model and in vitro.
Topics: Animals; Antiplatyhelmintic Agents; Artemether; Artemisinins; Artesunate; Bile Ducts; Disease Models, Animal; Fasciola hepatica; Fascioliasis; Female; Microscopy, Electron, Scanning; Rats; Rats, Wistar; Sesquiterpenes | 2006 |
A dimer of alpha- and beta-dihydroartemisinin: bis(3,6,9-trimethyl-3,12-epidioxy-3,4,5,5a,6,7,8,8a,9,10-decahydro-12H-pyrano[4,3-j][1,2]benzodioxepin-10-yl) ether.
Topics: Artemisinins; Crystallography, X-Ray; Dimerization; Molecular Structure; Sesquiterpenes | 2006 |
Manslaughter by fake artesunate in Asia--will Africa be next?
Topics: Adult; Africa; Antimalarials; Artemisinins; Artesunate; Asia; Drug and Narcotic Control; Drug Contamination; Drug Costs; Drug Packaging; Fraud; Global Health; Humans; Malaria; Male; Sesquiterpenes; Travel | 2006 |
Dihydroarteannuin ameliorates lupus symptom of BXSB mice by inhibiting production of TNF-alpha and blocking the signaling pathway NF-kappa B translocation.
Topics: Animals; Artemisinins; Blotting, Western; Cells, Cultured; Dose-Response Relationship, Drug; Intubation, Gastrointestinal; Lipopolysaccharides; Lupus Erythematosus, Systemic; Macrophages, Peritoneal; Male; Mice; Molecular Structure; Protein Transport; Sesquiterpenes; Signal Transduction; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2006 |
Artemisinin combination therapies.
Topics: Adult; Africa; Antimalarials; Artemisinins; Artesunate; Asia; Child, Preschool; Drug Therapy, Combination; Humans; Malaria, Falciparum; Mefloquine; Quinolines; Sesquiterpenes | 2006 |
Dihydroartemisinin inhibits angiogenesis induced by multiple myeloma RPMI8226 cells under hypoxic conditions via downregulation of vascular endothelial growth factor expression and suppression of vascular endothelial growth factor secretion.
Topics: Allantoin; Angiogenesis Inhibitors; Animals; Artemisinins; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Chick Embryo; Culture Media, Conditioned; Down-Regulation; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Extracellular Signal-Regulated MAP Kinases; Flow Cytometry; Humans; Hypoxia; Membranes; Multiple Myeloma; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sesquiterpenes; Signal Transduction; Tetrazolium Salts; Thiazoles; Vascular Endothelial Growth Factor A | 2006 |
Treatment of malaria in a mouse model by intranasal drug administration.
Topics: Administration, Intranasal; Animals; Antimalarials; Artemisinins; Disease Models, Animal; Drug Administration Schedule; Female; Malaria; Malaria, Cerebral; Mice; Mice, Inbred ICR; Parasitemia; Plasmodium berghei; Sesquiterpenes; Survival Analysis; Treatment Outcome | 2006 |
In vivo and in vitro investigations of the effects of the antimalarial drug dihydroartemisinin (DHA) on rat embryos.
Topics: Abnormalities, Multiple; Administration, Oral; Animals; Antimalarials; Artemisinins; Cell Death; Cesarean Section; Dose-Response Relationship, Drug; Embryo Culture Techniques; Embryo Loss; Embryo, Mammalian; Erythrocytes, Abnormal; Erythroid Precursor Cells; Erythropoiesis; Female; Fetal Death; Fetal Development; Gestational Age; Glutathione; Male; Rats; Rats, Sprague-Dawley; Sesquiterpenes | 2006 |
Population pharmacokinetics of artesunate and dihydroartemisinin following intra-rectal dosing of artesunate in malaria patients.
Topics: Administration, Rectal; Adolescent; Adult; Africa; Aging; Antimalarials; Artemisinins; Artesunate; Asia, Southeastern; Child; Child, Preschool; Demography; Female; Humans; Infant; Malaria; Male; Middle Aged; Parasitemia; Salvage Therapy; Sesquiterpenes; Sex Factors; Suppositories; Treatment Outcome | 2006 |
Assessment of the effect of mefloquine on artesunate pharmacokinetics in healthy male volunteers.
Topics: Adult; Antimalarials; Area Under Curve; Artemisinins; Artesunate; Chromatography, High Pressure Liquid; Drug Interactions; Humans; Male; Mefloquine; Middle Aged; Sesquiterpenes; Spectrophotometry, Ultraviolet | 2007 |
Quality control of active ingredients in artemisinin-derivative antimalarials within Kenya and DR Congo.
Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Capsules; Chromatography, High Pressure Liquid; Democratic Republic of the Congo; Dosage Forms; Endemic Diseases; Humans; Kenya; Malaria, Falciparum; Quality Control; Sesquiterpenes; Tablets | 2007 |
Liquid chromatography-tandem mass spectrometry assay for the quantitation of beta-dihydroartemisinin in rat plasma.
Topics: Animals; Antimalarials; Artemisinins; Chromatography, Liquid; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Wistar; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Sesquiterpenes; Tandem Mass Spectrometry | 2007 |
Resistance to dihydroartemisinin.
Topics: Animals; Antimalarials; Artemisinins; Drug Resistance; Plasmodium falciparum; Sesquiterpenes | 2006 |
In vitro antimalarial drug susceptibility and pfcrt mutation among fresh Plasmodium falciparum isolates from the Lao PDR (Laos).
Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; DNA, Protozoan; Drug Resistance; Ethanolamines; Female; Fluorenes; Humans; Inhibitory Concentration 50; Laos; Lumefantrine; Malaria, Falciparum; Male; Mefloquine; Membrane Transport Proteins; Middle Aged; Plasmodium falciparum; Point Mutation; Polymerase Chain Reaction; Protozoan Proteins; Sesquiterpenes | 2007 |
Artesunate and a major metabolite, dihydroartemisinin, diminish mitogen-induced lymphocyte proliferation and activation.
Topics: Adult; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Antimalarials; Artemisinins; Artesunate; Cells, Cultured; Cytokines; Dose-Response Relationship, Drug; Humans; Interleukin-2 Receptor alpha Subunit; Lectins, C-Type; Leukocytes, Mononuclear; Lymphocyte Activation; Mitogens; Phytohemagglutinins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sesquiterpenes | 2006 |
Effects of piperaquine, chloroquine, and amodiaquine on drug uptake and of these in combination with dihydroartemisinin against drug-sensitive and -resistant Plasmodium falciparum strains.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Chloroquine; Drug Antagonism; Drug Combinations; Drug Interactions; Drug Resistance; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines; Sesquiterpenes; Tritium | 2007 |
[Dihydroartemisinin inhibits proliferation and induces apoptosis of rat glioma C6 cells].
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Artemisinins; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Glioma; Inhibitory Concentration 50; Rats; Reactive Oxygen Species; Sesquiterpenes; Time Factors | 2007 |
Development of a pharmacodynamic model of murine malaria and antimalarial treatment with dihydroartemisinin.
Topics: Animals; Antimalarials; Artemisinins; Disease Models, Animal; Dose-Response Relationship, Drug; Erythrocyte Count; Erythrocytes; Malaria; Male; Mice; Mice, Inbred BALB C; Parasitemia; Plasmodium berghei; Sesquiterpenes | 2007 |
The role of calcium, P38 MAPK in dihydroartemisinin-induced apoptosis of lung cancer PC-14 cells.
Topics: Antimalarials; Apoptosis; Artemisinins; Blotting, Western; Calcium; Cell Line, Tumor; Chelating Agents; DNA Fragmentation; DNA, Neoplasm; Egtazic Acid; Enzyme Inhibitors; Flow Cytometry; Fluorescent Dyes; Humans; Imidazoles; Lung Neoplasms; p38 Mitogen-Activated Protein Kinases; Pyridines; Sesquiterpenes; Tetrazolium Salts; Thiazoles | 2008 |
Induction of apoptosis and inhibition of cell migration and tube-like formation by dihydroartemisinin in murine lymphatic endothelial cells.
Topics: Animals; Apoptosis; Artemisinins; bcl-2-Associated X Protein; Cell Movement; Cell Proliferation; Endothelial Cells; Female; Flow Cytometry; Gene Expression Regulation; Genes, bcl-2; Mice; Mice, Inbred BALB C; RNA, Messenger; Sesquiterpenes; Vascular Endothelial Growth Factor Receptor-3 | 2007 |
Dihydroartemisinin exerts cytotoxic effects and inhibits hypoxia inducible factor-1alpha activation in C6 glioma cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Artemisinins; Cell Hypoxia; Cell Proliferation; Cell Survival; Cells, Cultured; Chelating Agents; Deferoxamine; Ferrous Compounds; Glioma; Hypoxia-Inducible Factor 1, alpha Subunit; Rats; Reactive Oxygen Species; Sesquiterpenes; Tumor Cells, Cultured; Vascular Endothelial Growth Factors | 2007 |
CD4 count, viral load and parasite density of HIV positive individuals undergoing malaria treatment with dihydroartemisinin in Benin City, Edo state, Nigeria.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; CD4 Lymphocyte Count; Child; Child, Preschool; Female; HIV Infections; HIV-1; Humans; Infant; Infant, Newborn; Malaria; Male; Middle Aged; Nigeria; Prospective Studies; Sesquiterpenes; Urban Health; Viral Load | 2007 |
Pharmacodynamics of doxycycline in a murine malaria model.
Topics: Animals; Antimalarials; Artemisinins; Disease Models, Animal; Doxycycline; Drug Synergism; Drug Therapy, Combination; Malaria; Male; Mice; Mice, Inbred BALB C; Plasmodium berghei; Sesquiterpenes | 2007 |
Differential effects on angiogenesis of two antimalarial compounds, dihydroartemisinin and artemisone: implications for embryotoxicity.
Topics: Adult; Animals; Antimalarials; Aorta, Thoracic; Artemisinins; Capillaries; Cell Line; Cell Proliferation; Cytokines; Dose-Response Relationship, Drug; Embryo, Mammalian; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Female; Fibronectins; Humans; Male; Neovascularization, Physiologic; Neural Tube; Pregnancy; Rats; Rats, Inbred F344; Sesquiterpenes; Teratogens; Tetrazolium Salts; Thiazoles; Vascular Endothelial Growth Factor A | 2007 |
Pharmacokinetics and pharmacodynamics of piperaquine in a murine malaria model.
Topics: Animals; Antimalarials; Artemisinins; Disease Models, Animal; Drug Therapy, Combination; Humans; Malaria; Male; Mice; Parasitemia; Plasmodium berghei; Quinolines; Sesquiterpenes; Treatment Outcome | 2008 |
Plasmodium berghei: parasite clearance after treatment with dihydroartemisinin in an asplenic murine malaria model.
Topics: Animals; Antimalarials; Artemisinins; Aspartate Aminotransferases; Disease Models, Animal; Erythrocytes; Hemeproteins; Hemoglobins; Leukocyte Count; Liver; Lung; Malaria; Male; Mice; Mice, Inbred BALB C; Parasitemia; Plasmodium berghei; Platelet Count; Sesquiterpenes; Spleen; Splenectomy | 2008 |
Assessment of in vitro antimalarial interactions between dihydroartemisinin and fosmidomycin.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance; Fosfomycin; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Plasmodium falciparum; Schizonts; Sesquiterpenes | 2007 |
Orally active esters of dihydroartemisinin: Synthesis and antimalarial activity against multidrug-resistant Plasmodium yoelii in mice.
Topics: Adamantane; Administration, Oral; Animals; Antimalarials; Artemisinins; Biphenyl Compounds; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Esters; Malaria; Mice; Models, Molecular; Plasmodium yoelii; Sesquiterpenes; Structure-Activity Relationship | 2008 |
A new decomposition product of dihydroartemisinin.
Topics: Antimalarials; Artemisinins; Chromatography, Thin Layer; Indicators and Reagents; Magnetic Resonance Spectroscopy; Mass Spectrometry; Sesquiterpenes; Spectrometry, Mass, Electrospray Ionization | 2007 |
Human fortilin is a molecular target of dihydroartemisinin.
Topics: Antineoplastic Agents; Apoptosis; Artemisinins; Biomarkers, Tumor; Cell Line; DNA Fragmentation; Half-Life; Humans; Proteasome Endopeptidase Complex; RNA, Messenger; Sesquiterpenes; Tumor Protein, Translationally-Controlled 1; Ubiquitin | 2008 |
Optimization of an LC-MS method for the determination of artesunate and dihydroartemisinin plasma levels using liquid-liquid extraction.
Topics: Antimalarials; Artemisinins; Artesunate; Atmospheric Pressure; Chromatography, High Pressure Liquid; Humans; Reproducibility of Results; Sesquiterpenes; Spectrometry, Mass, Electrospray Ionization | 2008 |
Formation, physical stability and in vitro antimalarial activity of dihydroartemisinin nanosuspensions obtained by co-grinding method.
Topics: Animals; Antimalarials; Artemisinins; Crystallization; Deoxycholic Acid; Drug Stability; Excipients; In Vitro Techniques; Microscopy, Atomic Force; Microscopy, Electron, Transmission; Nanoparticles; Particle Size; Plasmodium falciparum; Povidone; Sesquiterpenes; Solubility; Suspensions | 2008 |
Biological activity of dihydroartemisinin in canine osteosarcoma cell lines.
Topics: Animals; Antineoplastic Agents; Apoptosis; Artemisinins; Blotting, Western; Bone Neoplasms; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Survival; DNA Fragmentation; Dog Diseases; Dogs; Drug Screening Assays, Antitumor; Flow Cytometry; Inhibitory Concentration 50; Osteosarcoma; Reactive Oxygen Species; Sesquiterpenes | 2008 |
Solid dispersions of dihydroartemisinin in polyvinylpyrrolidone.
Topics: Antimalarials; Artemisinins; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Drug Carriers; Drug Compounding; Hydrogen Bonding; Povidone; Sesquiterpenes; Solubility; Solvents; Spectroscopy, Fourier Transform Infrared; Technology, Pharmaceutical; Temperature; Thermodynamics; X-Ray Diffraction | 2008 |
Dihydroartemisinin induces apoptosis in human leukemia cells HL60 via downregulation of transferrin receptor expression.
Topics: Antimalarials; Antineoplastic Agents; Apoptosis; Artemisinins; bcl-2-Associated X Protein; Caspase 3; DNA Fragmentation; Dose-Response Relationship, Drug; Down-Regulation; Drug Screening Assays, Antitumor; HL-60 Cells; Humans; Mitochondria; Proto-Oncogene Proteins c-bcl-2; Receptors, Transferrin; Sesquiterpenes; Staining and Labeling; Time Factors; Trypan Blue | 2008 |