Page last updated: 2024-08-26

artenimol and artemisinin

artenimol has been researched along with artemisinin in 147 studies

Research

Studies (147)

Timeframe	Studies, this research(%)	All Research%
pre-1990	10 (6.80)	18.7374
1990's	23 (15.65)	18.2507
2000's	15 (10.20)	29.6817
2010's	74 (50.34)	24.3611
2020's	25 (17.01)	2.80

Authors

Authors	Studies
Benedetti, P; Bizzarri, BM; Botta, L; Cesarini, S; Cirigliano, A; Filippi, S; Fiorucci, D; Negri, R; Paiardini, A; Rinaldi, T; Saladino, R; Zippilli, C	1
Li, XQ; Liu, XX; Wei, MX; Yang, JH; Yang, PW; Yu, JY; Zhang, MW	1
Albuquerque, IS; Burojević, J; D'Alessandro, S; Djurković-Djaković, O; Konstantinović, J; Machado, M; Pecic, S; Prudêncio, M; Sciotti, RJ; Šolaja, BA; Srbljanović, J; Štajner, T; Taramelli, D; Terzić, N; Tot, M; Verbić, T; Zlatović, M	1
Bhakuni, RS; Gaur, R; Malik, FA; Pathania, AS; Verma, RK	1
Dong, G; Liu, N; Sheng, C; Wang, Y; Wu, S	1
Athanassopoulos, CM; Kokkinogouli, V; Lamprou, M; Magoulas, GE; Pantazaka, E; Papadimitriou, E; Papaioannou, D; Skondra, L; Tsigkou, T; Tsoukala, P	1
Bai, L; Gong, J; Jin, Y; Peng, T; Shi, J; Tong, R; Wei, X; Zhou, Y	1
He, Y; Hu, P; Yang, X; Yu, Z; Zhang, N	1
He, Y; Li, G; Li, S; Meng, Q; Sun, D; Yang, X; Yuan, S	1
Çapcı Karagöz, A; Efferth, T; Friedrich, O; Gruber, L; Hahn, F; Hampel, F; Kappes, B; Klein, V; Leidenberger, M; Marschall, M; Reiter, C; Seo, EJ; Tsogoeva, SB	1
Chang, L; Ding, C; Feng, LS; Gao, C; Wu, X; Xu, Z; Yan, XF; Zhao, F	1
Ahmad, F; Giri, SK; Gour, R; Kartha, KPR; Lal Karna, SK; Pokharel, YR; Prajapati, SK	1
Liu, Y; Xu, Z; Zhao, SJ	1
Emami, SA; Taleghani, A; Tayarani-Najaran, Z	1
Aratikatla, EK; Asad, M; Bhattacharya, AK; Datta, G; Kalamuddin, M; Malhotra, P; Mohmmed, A; Rana, KC; Sundararaman, S	1
Leskovac, V; Peggins, JO	1
Gosser, DK; Meshnick, SR; Zhang, F	1
Ayalp, A; Bishop, SJ; el-Feraly, FS; Tawfik, AF	1
Song, ZY; Zhao, KC	2
Gu, HM; Peters, W; Warhurst, DC	2
Li, ZL; Peters, W; Robinson, BL; Warhurst, DC	1
Ashmore, RW; Halverson, JM; Lin, AJ; Ridder, WE; Smyth, MH; Theoharides, AD; Zhou, ZM	1
Cooke, DW; Durack, DT; Lallinger, GJ	1
Chen, YX; Ji, RY; Li, Y; Yu, PL	2
Ellis, DS; Gu, HM; Li, ZL; Peters, W; Robinson, BL; Tovey, G; Warhurst, DC	1
Gu, HM; Li, ZL; Peters, W; Warhurst, DC	1
Ager, AL; Klayman, DL; Lin, AJ	1
Fu, LC; Guo, XB; Jian, HX; Li, GQ; Wang, XH	1
Janse, CJ; Kos, J; Lugt, CB; Waters, AP	1
Gao, HL; Long, ZZ; Xie, SS; Yang, SX	1
Avery, MA; Bonk, JD; Chong, WK; Goins, DK; Khan, I; Mehrotra, S; Milhous, W; Miller, R; Venkatesan, S; Wyandt, C	1
Davis, TM; Johnston, WA; Manning, LS; Skinner, TS	1
Benakis, A; Loutan, L; Paris, M; Plessas, CT; Plessas, ST	1
Heppner, DG; Kawamoto, F; Nguyen, TD; Sookto, P; Trieu, NT; Wimonwattrawatee, T; Wongsrichanalai, C	1
Kyle, DE; Lin, AJ; Zikry, AB	1
Butter, JJ; Portier, EJ; van Agtmael, MA; van Boxtel, CJ	1
Berens, RL; Curiel, TJ; Krug, EC; Nash, PB	1
Bhisutthibhan, J; Carlton, J; Dame, JB; Hossler, PA; Meshnick, SR; Pan, XQ; Walker, DJ; Yowell, CA	1
Li, Y; Wu, YL	1
Le Bras, J	1
McLean, WG; Ward, SA	1
Looareesuwan, S; Wilairatana, P	1
Eggelte, TA; van Agtmael, MA; van Boxtel, CJ; Vuong, TD	1
Duraisingh, MT; Jones, P; Pinder, M; Sambou, I; von Seidlein, L; Warhurst, DC	1
Dodd, CC; Edwards, G; McLean, WG; Park, BK; Sadler, CJ; Smith, SL; Ward, SA	1
Kollaritsch, H; Krudsood, S; Looareesuwan, S; Noedl, H; Wernsdorfer, WH; Wiedermann, G; Wilairatana, P	1
Ashton, M; Davis, TM; Hai, TN; Huong, DX; Ilett, KF; Zhang, SQ	1
Tu, Y	1
Mankhetkorn, S; Reungpatthanaphong, P	1
Basilico, N; Haynes, RK; Monti, D; Olliaro, P; Parapini, S; Taramelli, D	1
Brewer, TG; Kyle, DE; Peggins, JO; Teja-Isavadharm, P; Webster, HK; White, NJ	1
Folb, PI; Smith, P; Waako, PJ	1
Ashley, E; Aye, KZ; Barends, M; Htet, L; Kyaw, MK; Lindegardh, N; Lwin, S; Phe, O; Singtoroj, T; Smithuis, F; Stepniewska, K; White, NJ	1
Davis, TM; Ilett, KF; Karunajeewa, HA; Manning, L; Mueller, I	1
Gottstein, B; Hemphill, A; Keiser, J; Lany, C; Ortega-Mora, LM; Roethlisberger, C; Spicher, M; Stadelmann, B	1
Hou, J; Wang, D; Wang, H; Zhang, R	1
Lai, CS; Mansor, SM; Muniandy, A; Nair, NK; Navaratnam, V; Olliaro, PL	1
Song, JP; Tan, B; Trung, TN; Van Phuc, D	1
Donegan, S; Garner, P; Olliaro, P; Sinclair, D; Zani, B	1
Lacoste, E; Lai, H; Nakase, I; Sasaki, T; Singh, NP	1
Arinaitwe, E; Bigira, V; Dorsey, G; Kakuru, A; Kamya, M; Sandison, T; Tappero, JW; Verret, WJ; Wanzira, H	1
Björkman, A; Ferreira, PE; Gil, JP; Jörnhagen, L; Kone, A; Malmberg, M; Nosten, F; Petzold, M; Schmidt, BA; Veiga, MI	1
Ferreira, JF; Lai, HC; Park, JS; Singh, NP	1
Abu-Bakar, N; Bottova, I; Crespo-Ortiz, MP; Kenny, S; Klonis, N; Rosenthal, PJ; Tilley, L	1
Akao, N; Anyan, WK; Asahi, H; Ayi, I; Boakye, DA; Kumagai, T; Kwansa-Bentum, B; Ohta, N; Otchere, J; Suzuki, T; Wilson, MD	1
Du, F; Liu, T; Wan, Y; Xing, J; Zhu, F	1
Jessing, KK; Juhler, RK; Strobel, BW	1
Du, F; Liu, T; Xing, J; Zhu, F	1
Gerhardt, TE; Kim, BJ; Lai, HC; Park, JS; Sasaki, T; Singh, NP; Wang, S	1
Basilico, N; Corbett, Y; D'Alessandro, S; Finaurini, S; Haynes, RK; Olliaro, P; Parapini, S; Taramelli, D	1
Goodlett, DR; Kirby, BJ; Wan, Y; Whittington, D; Xing, J	1
Baldwin, AS; Dan, HC; Gu, AD; Guo, Z; Hao, W; Wan, YY; Wang, Y; Zhao, YG	1
Ariey, F; Beck, HP; Csajka, C; Decosterd, LA; Duong, S; Genton, B; Guidi, M; Kabanywanyi, AM; Olliaro, P; Staehli Hodel, EM	1
Kan, WJ; Li, MM; Song, JS; Yu, PX; Yu, WY; Zhao, F	1
Efferth, T; Eichhorn, T; Schneider, D; Veerappan, A; Zeino, M	1
Aubouy, A; Dahlström, S; Deloron, P; Ezinmègnon, S; Faucher, JF; Houzé, P; Houzé, S; Kendjo, E; Le Bras, J; Maïga-Ascofaré, O; Massougbodji, A; Wakpo, A	1
Cremers, S; Fidock, DA; Henrich, PP; Kyle, DE; O'Brien, C; Sáenz, FE	1
Abiola, A; Faye, B; Folly, K; Gaye, O; Lo, AC; Ndiaye, JL; Ndiaye, LA; Ndiaye, M; Sow, D; Sylla, K; Tine, RC	1
Ashton, M; Ericsson, T; Hoffmann, KJ; Sundell, J; Torkelsson, A	1
Li, GX; Wang, W; Wang, YH; Xu, FL; Zhang, XG; Zhao, SS	1
Chen, K; Cui, L; Fan, Q; Feng, G; Hao, M; Lin, Y; Sun, L; Wu, Y; Yang, Z; Zhao, Z	1
Achan, J; Arinaitwe, E; Charlebois, E; Clark, TD; Dorsey, G; Havlir, D; Ikilezi, G; Kakuru, A; Kamya, MR; Muhindo, MK; Mwangwa, F; Rosenthal, PJ; Ruel, T; Tappero, JW	1
Cheng, Z; Jiang, X; Liu, R	1
Amaratunga, C; Fairhurst, RM; Neal, AT	1
Chen, N; Cheng, Q; Gatton, ML; Kyle, DE; LaCrue, AN; Teuscher, F; Waters, NC	1
Lai, HC; Park, J; Sasaki, T; Singh, M; Singh, NP	1
Batty, KT; Senarathna, SM	1
Basilico, N; Bosisio, E; Colombo, E; Dell'Agli, M; Haynes, RK; Magenta, D; Parapini, S; Sangiovanni, E; Taramelli, D	1
Diep, NK; Du, ZJ; Fukumoto, Y; Inokuchi, T; Kiguchi, R; Nokami, J; Świtalska, M; Wang, L; Wang, N; Wietrzyk, J	1
Baker, M; Bousema, T; Cairns, M; D'Alessandro, U; Ferguson, NM; Ghani, AC; Griffin, JT; Hugo, P; Jagoe, G; Okell, LC; Tarning, J; Ubben, D	1
Lai, HC; Park, J; Sasaki, T; Singh, NP	1
Bhattacharjee, S; Chotivanich, K; Dondorp, AM; Emrich, S; Estiu, G; Ghorbal, M; Haldar, K; Liu, H; Lopez-Rubio, JJ; Mbengue, A; Mohandas, N; Nguon, C; Njimoh, DL; Pandharkar, T; Pfrender, M; Rizk, SS; Ryan, Y; Stahelin, RV; Wiest, O	1
Buathong, N; Chanarat, N; Chann, S; Chaorattanakawee, S; Chuor, CM; Gosi, P; Heng, TK; Jacob, C; Kong, N; Kuntawunginn, W; Lanteri, CA; Lin, JT; Lon, C; Plowe, C; Prom, S; Saingam, P; Saunders, DL; Se, Y; Sea, D; Sriwichai, S; Sundrakes, S; Takala-Harrison, S; Tangthongchaiwiriya, K; Teja-Isavadharm, P; Tyner, SD; Yingyuen, K; Yom, Y	1
Bouth, DM; Char, MC; Domergue, A; Duru, V; Khim, N; Kim, S; Leang, R; Menard, D; Ringwald, P; Song, L; Tarning, J; Taylor, WR; Witkowski, B	1
Brashear, A; Cabrera, M; Cui, L; Gupta, B; Hu, Y; Kemirembe, K; Li, X; Liang, X; Miao, J; Shrestha, S; Sun, X; Wang, Y; Wang, Z; Wu, Y; Yang, Z; Zhang, Y	1
d'Alessandro, U; Dahal, P; Dorsey, G; Guerin, PJ; Nsanzabana, C; Price, RN; Sibley, CH; Stepniewska, K; Talisuna, AO	1
Bonfill, M; Cusido, RM; Dilshad, E; Mirza, B; Ramirez Estrada, K	1
Baird, JK; Boni, MF; Dondorp, AM; Farrar, J; Lam, HM; Nguyen, TD; Olliaro, P; Thwaites, GE; White, NJ	1
Acheampong, PR; Antwi, GD; Bart Plange, C; Cairns, M; Chandramohan, D; Tagbor, H	1
Fowkes, FJI; Jittamala, P; McGready, R; Moore, KA; Nosten, F; Paw, MK; Pimanpanarak, M; Rijken, MJ; Simpson, JA; White, NJ; Wiladphaingern, J	1
Beeching, NJ; Bell, DJ; Chiodini, PL; Lalloo, DG; Shingadia, D; Whitty, CJM	1
Cai, X; Cheramy, J; Dezhahang, Z; Poopari, MR; Savin, A; Xu, Y; Zhang, Y	1
Cao, P; Charman, SA; Creek, DJ; Giannangelo, C; Klonis, N; McCaw, J; Tilley, L; Xie, SC; Yang, T	1
Aderoyeje, T; Adewoye, EO; Akano, K; Ayede, AI; Fatunmbi, B; Ntadom, G; Sowunmi, A	1
Cabral, L; Cristiano, ML; Lobo, L; Nogueira, F; Sousa, Bd	1
Chavchich, M; Chen, N; Cheng, Q; Gray, KA; Gresty, KJ; Gutteridge, CE; Peatey, CL; Waters, NC; Zhang, V	1
De Smet, M; Dondorp, A; Etienne, W; Falq, G; Imwong, M; Kindermans, JM; Nguon, C; Rekol, H; Van Den Bergh, R	1
Iyengar, K; Roepe, PD; Siriwardana, A	1
Bouhired, S; Duparc, S; Goyal, N; Green, JA; Hussaini, A; Jones, SW; Koh, GC; Kostov, I; Mohamed, K; Taylor, M; Wolstenholm, A	1
Han, F; Lee, IS	1
Rogerson, SJ; Unger, HW	1
Liu, XJ; Peng, HJ; Wei, HX; Xia, J; Zhou, LJ	1
Khositnithikul, R; Mungthin, M; Sitthichot, N; Suwandittakul, N; Ward, SA; Watanatanasup, E	1
Dehaen, W; Hayat, MQ; Iram, S; Jana, S; Pannecouque, C; Thomas, J	1
Combrinck, JM; Cooper, RA; Cowell, AN; Dhingra, SK; Egan, TJ; Fidock, DA; Gupta, P; Henrich, PP; Hoke, JM; Mok, S; Okombo, J; Redhi, D; Stegman, ML; Winzeler, E; Yeo, T	1
Ang, X; Bifani, P; Bodenreider, C; Bonamy, GMC; Chavchich, M; Dembele, L; Diagana, TT; Edstein, MD; Fidock, DA; Lim, MY; Nosten, F; Russell, BM; Selva, JJ; Straimer, J; Yeung, BKS	1
Aweeka, F; Conrad, MD; Dorsey, G; Foster, M; Havlir, DV; Huang, L; Jagannathan, P; Kakuru, A; Kamya, MR; Legac, J; Mota, D; Nayebare, P; Rosenthal, PJ; Tukwasibwe, S; Tumwebaze, P; Wallender, E; Whalen, M	1
Anh, CX; Birrell, GW; Chavchich, M; Edstein, MD; Quang, NN; Rowcliffe, K; Travers, T; van Breda, K	1
Cao, P; Dini, S; Fowkes, FJI; McCaw, JM; Price, RN; Simpson, JA; van der Pluijm, RW; Zaloumis, S	1
Dai, R; Dai, T; Guo, Z; Jiang, W; Xie, Y	1
Beavogui, AH; Borghini-Fuhrer, I; Djimdé, AA; Duparc, S; Felices, M; Funck-Brentano, C; Khan, Y; Ouedraogo, JB; Ouologuem, N; Sagara, I; Sirima, SB; Soulama, I; Voiriot, P	1
Benthani, FA; Bian, ZX; Chen, GQ; Jiang, X; Liang, D; Wu, J	1
Guan, J; Huang, P; Li, F; Liu, L; Liu, Z; Lu, L; Qi, X; Su, T; Wang, D; Wang, Y	1
Bienvenu, AL; Bonnot, G; Kouakou, YI; Lavoignat, A; Leboucher, G; Picot, S; Tod, M	1
Aweeka, F; Huang, L; Hughes, E; Kajubi, R; Mwebaza, N; Mwima, MW; Nguyen, V; Nyunt, MM; Orukan, F; Parikh, S	1
Anderson, TJC; Button-Simons, KA; Cassady, Z; Checkley, LA; Davis, SZ; Ferdig, MT; Foster, GJ; McDew-White, M; Nosten, FH; Shoue, DA; Sievert, MAC; Singh, PP; Vendrely, KM	1
Boonhok, R; Cabrera, M; Cao, Y; Cui, L; Liang, X; Mbenda, HGN; Miao, J; Min, H; Qin, J; Siddiqui, FA; Wang, M; Zhu, X	1
Amaratunga, C; Amato, R; Anvikar, AR; Ashley, E; Baidya, S; Behera, PK; Callery, JJ; Chau, NH; Cheah, PY; Chotivanich, K; Chutasmit, K; Day, NPJ; Dhorda, M; Dondorp, AM; Fairhurst, RM; Faiz, A; Fanello, C; Gantait, K; Ghosh, T; Gonçalves, S; Grobusch, MP; Hanboonkunupakarn, B; Heaton, J; Hien, TT; Hlaing, TM; Hoa, NT; Hoglund, RM; Huy, R; Imwong, M; Jacob, CG; Jittamala, P; Kaewmok, W; Kwiatkowski, DP; Lek, D; Lin, K; Mao, S; Maude, RJ; Mayxay, M; Miotto, O; Mohanty, AK; Mukaka, M; Newton, PN; Onyamboko, M; Oun, S; Pearson, RD; Peto, TJ; Pukrittayakamee, S; Pyae Phyo, A; Runcharern, R; Saelow, C; Satpathi, P; Satpathi, S; Smithuis, F; Sovann, Y; Sreng, S; Suon, S; Tarning, J; Thanh, NV; Thant, M; Thuy-Nhien, NT; Tripura, A; Tripura, R; Ul Islam, A; Valecha, N; van der Pluijm, RW; van Vugt, M; von Seidlein, L; Waithira, N; White, NJ; Winterberg, M; Woodrow, CJ; Yen, S	1
Boydston, EA; Fidock, DA; Gnädig, NF; Harding, CR; Herneisen, AL; Lourido, S; Markus, BM; Okombo, J; Petrova, B; Sidik, SM; Ward, KE	1
Gille, L; Machín, L; Monzote, L; Nápoles, R	1
Boaventura, S; Gadelha, FR; Garcia, VL; Grazzia, N; Miguel, DC	1
Fidock, DA; Huang, Y; Nair, MS; Polyak, SJ; Towler, MJ; Wagoner, J; Weathers, PJ	1
Coghi, P; Gianoncelli, A; Mastinu, A; Memo, M; Ng, JPL; Ribaudo, G; Wong, VKW; Yang, LJ	1
Ashley, EA; Aung, H; Aung, Y; Day, NPJ; Dondorp, AM; Heaton, J; Hlaing, T; Imwong, M; Indrasuta, C; Khant, ZS; Kyaw, TT; Maung, SM; McLean, ARD; Phyo, AK; Smithuis, FM; Soe, K; Swe, MMM; Tun, KM; Tun, NN; von Seidlein, L; White, NJ	1
Cui, Z; Jiang, T; Li, C; Li, L; Li, S; Ma, J; Qin, T; Shi, H; Tang, T; Wang, H; Xu, W; Zhou, H	1
Arora, P; Malhotra, P; Mohmmed, A; Mukhtar, O; Narwal, M; Thakur, V	1
Chen, Y; Cheng, Y; Li, P; Liu, H; Lu, X; Ma, Y; Song, C; Wang, Y; Zhang, Z	1
Cao, X; Hu, D; Huang, M; Jiang, Y; Ma, Y; Shi, Y; Song, X	1
Adjei, GO; Ahorhorlu, SY; Alifrangis, M; Duah-Quashie, NO; Dzudzor, B; Hansson, H; Jensen, RW; Kudzi, W; Nartey, ET; Quashie, NB; Wang, CW; Zoiku, F	1
Akala, HM; Amwoma, JG; Andagalu, BM; Chemwor, GC; Cheruiyot, AC; Egbo, TE; Garges, EC; Juma, DW; Juma, JA; Kamau, E; Mwakio, EW; Ogutu, BR; Okoth, RO; Onyango, IA; Opot, BH; Roth, AL; Wakoli, DM; Watson, OJ; Yedah, RA	1
Barman, M; Bhandari, V; Dandasena, D; Kamble, S; Sharma, P; Singh, S; Subudhi, M; Suresh, A	1
Baird, JK; Berni, A; Budiman, W; Cedar, E; Chand, K; Crenna-Darusallam, C; Duparc, S; Ekawati, LL; Elyazar, I; Fernando, D; Fletcher, K; Goyal, N; Green, JA; Instiaty, I; Jones, S; Kleim, JP; Lardo, S; Martin, A; Noviyanti, R; Prasetya, CB; Rolfe, K; Santy, YW; Satyagraha, AW; Sharma, H; Soebandrio, A; Subekti, D; Sutanto, I; Tan, LK; Taylor, M	1
Bailly, J; Bei, AK; Coppée, R; Diallo, MA; Diédhiou, Y; Dièye, B; Diongue, K; Doderer-Lang, C; Fall, A; Garba, MN; Gaye, A; Mama, A; Mbaye, A; Mbaye, AM; Ménard, D; Ndiaye, D; Ndiaye, IM; Ndiaye, T; Thiaw, AB; Tine, A; Yade, MS	1
D'Alessandro, U; Dabira, ED; Diakite, H; Djimde, M; Dorlo, TP; Erhart, A; González, R; Kabore, B; Kayentao, K; Keita, M; Macuacua, S; Menendez, C; Mens, P; Muhindo, HM; Piqueras, M; Sagara, I; Schallig, H; Sevene, E; Tinto, H; Traore, M; Tshiongo, JK; Vala, A	1

Reviews

15 review(s) available for artenimol and artemisinin

Article	Year
Tackling Fungal Resistance by Biofilm Inhibitors. Journal of medicinal chemistry, 2017, 03-23, Volume: 60, Issue:6 Topics: Animals; Antifungal Agents; Biofilms; Drug Discovery; Drug Resistance, Fungal; Fungi; Humans; Models, Molecular; Mycoses; Small Molecule Libraries	2017
Inhibitors of phosphodiesterase as cancer therapeutics. European journal of medicinal chemistry, 2018, Apr-25, Volume: 150 Topics: Animals; Antineoplastic Agents; Cell Proliferation; Dose-Response Relationship, Drug; Humans; Molecular Structure; Neoplasms; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Structure-Activity Relationship	2018
Recent advances of tetrazole derivatives as potential anti-tubercular and anti-malarial agents. European journal of medicinal chemistry, 2019, Feb-01, Volume: 163 Topics: Animals; Antimalarials; Antitubercular Agents; Humans; Structure-Activity Relationship; Tetrazoles	2019
1,2,3-Triazole-containing hybrids as potential anticancer agents: Current developments, action mechanisms and structure-activity relationships. European journal of medicinal chemistry, 2019, Dec-01, Volume: 183 Topics: Antineoplastic Agents; Humans; Molecular Structure; Neoplasms; Structure-Activity Relationship; Triazoles	2019
Artemisia: a promising plant for the treatment of cancer. Bioorganic & medicinal chemistry, 2020, 01-01, Volume: 28, Issue:1 Topics: Animals; Antineoplastic Agents, Phytogenic; Artemisia; Cell Proliferation; Humans; Molecular Structure; Neoplasms; Neoplasms, Experimental; Plant Extracts; Plants, Medicinal	2020
Studies of qinghaosu and its active derivatives in biological materials and their pharmacokinetics. Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao, 1989, Volume: 4, Issue:4 Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Sesquiterpenes; Structure-Activity Relationship	1989
How Chinese scientists discovered qinghaosu (artemisinin) and developed its derivatives? What are the future perspectives? Medecine tropicale : revue du Corps de sante colonial, 1998, Volume: 58, Issue:3 Suppl Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Drug Evaluation; Drug Resistance; Forecasting; Humans; Malaria, Falciparum; Medicine, Chinese Traditional; Sesquiterpenes	1998
The rational use of qinghaosu and its derivatives: what is the future of new compounds? Medecine tropicale : revue du Corps de sante colonial, 1998, Volume: 58, Issue:3 Suppl Topics: Administration, Oral; Administration, Rectal; Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Drug and Narcotic Control; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Registries; Sesquiterpenes; Suppositories; Thailand	1998
Rectal administration of artemisinin derivatives for the treatment of malaria. JAMA, 2007, Jun-06, Volume: 297, Issue:21 Topics: Administration, Rectal; Area Under Curve; Artemether; Artemisinins; Artesunate; Humans; Malaria; Sesquiterpenes	2007
Artemisinin-based combination therapy for treating uncomplicated malaria. The Cochrane database of systematic reviews, 2009, Jul-08, Issue:3 Topics: Antimalarials; Artemisinins; Artesunate; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Lumefantrine; Malaria; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Parasitemia; Pyrimethamine; Quinolines; Randomized Controlled Trials as Topic; Sulfadoxine	2009
A review of dihydroartemisinin as another gift from traditional Chinese medicine not only for malaria control but also for schistosomiasis control. Parasitology research, 2014, Volume: 113, Issue:5 Topics: Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Drugs, Chinese Herbal; Female; Malaria, Falciparum; Mice; Praziquantel; Schistosomiasis japonica; Schistosomicides	2014
Clinical determinants of early parasitological response to ACTs in African patients with uncomplicated falciparum malaria: a literature review and meta-analysis of individual patient data. BMC medicine, 2015, Sep-07, Volume: 13 Topics: Africa; Africa South of the Sahara; Amodiaquine; Antimalarials; Artemisinins; Drug Combinations; Drug Therapy, Combination; Humans; Infant; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Prospective Studies; Quinolines	2015
Prevention and control of malaria in pregnancy - new threats, new opportunities? Expert review of anti-infective therapy, 2017, Volume: 15, Issue:4 Topics: Adult; Animals; Antimalarials; Artemisinins; Culicidae; Drug Combinations; Drug Resistance; Female; Humans; Insecticide-Treated Bednets; Malaria, Falciparum; Malaria, Vivax; Pregnancy; Pregnancy Complications, Parasitic; Primary Prevention; Pyrimethamine; Quinolines; Sulfadoxine	2017
Risk of drug resistance in Plasmodium falciparum malaria therapy-a systematic review and meta-analysis. Parasitology research, 2017, Volume: 116, Issue:2 Topics: Amodiaquine; Antimalarials; Artemisinins; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinolines; Risk; Sulfadoxine	2017
Systematic review of artesunate pharmacokinetics: Implication for treatment of resistant malaria. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2019, Volume: 89 Topics: Administration, Intravenous; Administration, Oral; Antimalarials; Artemisinins; Artesunate; Asia, Southeastern; Drug Monitoring; Drug Resistance; Humans; Malaria; Malaria, Falciparum	2019

Trials

17 trial(s) available for artenimol and artemisinin

Article	Year
Pharmacokinetics of artemisinin and artesunate after oral administration in healthy volunteers. The American journal of tropical medicine and hygiene, 1997, Volume: 56, Issue:1 Topics: Administration, Oral; Adult; Antimalarials; Area Under Curve; Artemisinins; Artesunate; Female; Half-Life; Humans; Male; Metabolic Clearance Rate; Middle Aged; Sesquiterpenes; Tablets	1997
Multiple dose study of interactions between artesunate and artemisinin in healthy volunteers. British journal of clinical pharmacology, 2001, Volume: 52, Issue:4 Topics: Administration, Oral; Adult; Antimalarials; Area Under Curve; Artemisinins; Artesunate; Chromatography, High Pressure Liquid; Drug Administration Schedule; Drug Interactions; Half-Life; Humans; Linear Models; Male; Metabolic Clearance Rate; Sesquiterpenes	2001
Efficacy and effectiveness of dihydroartemisinin-piperaquine versus artesunate-mefloquine in falciparum malaria: an open-label randomised comparison. Lancet (London, England), 2006, 06-24, Volume: 367, Issue:9528 Topics: Adolescent; Animals; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Falciparum; Male; Mefloquine; Myanmar; Plasmodium falciparum; Quinolines; Recurrence; Sesquiterpenes; Treatment Outcome	2006
Validation of high performance liquid chromatography-electrochemical detection methods with simultaneous extraction procedure for the determination of artesunate, dihydroartemisinin, amodiaquine and desethylamodiaquine in human plasma for application in c Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2009, Feb-15, Volume: 877, Issue:5-6 Topics: Administration, Oral; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Chromatography, High Pressure Liquid; Drug Combinations; Drug Stability; Electrochemistry; Humans; Solid Phase Extraction	2009
A randomized, controlled trial of artemisinin-piperaquine vs dihydroartemisinin-piperaquine phosphate in treatment of falciparum malaria. Chinese journal of integrative medicine, 2009, Volume: 15, Issue:3 Topics: Adolescent; Adult; Anti-Infective Agents; Antimalarials; Artemisinins; Drug Combinations; Female; Humans; Integrative Medicine; Malaria, Falciparum; Male; Quinolines; Treatment Outcome; Young Adult	2009
Effect of nutritional status on response to treatment with artemisinin-based combination therapy in young Ugandan children with malaria. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:6 Topics: Antimalarials; Artemisinins; Drug Therapy, Combination; Humans; Infant; Malaria; Malnutrition; Parasitemia; Quinolines	2011
Monitoring the efficacy and safety of three artemisinin based-combinations therapies in Senegal: results from two years surveillance. BMC infectious diseases, 2013, Dec-20, Volume: 13 Topics: Adolescent; Adult; Amodiaquine; Antimalarials; Artemisinins; Child; Child, Preschool; Drug Combinations; Female; Humans; Malaria, Falciparum; Male; Plasmodium falciparum; Population Surveillance; Quinolines; Senegal; Young Adult	2013
Artemisinin-based combination therapies are efficacious and safe for treatment of uncomplicated malaria in HIV-infected Ugandan children. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2014, Aug-01, Volume: 59, Issue:3 Topics: Antimalarials; Artemisinins; Child, Preschool; Cohort Studies; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Infant; Lopinavir; Malaria; Male; Nevirapine; Parasitemia; Quinolines; Reverse Transcriptase Inhibitors; Ritonavir; Treatment Outcome; Uganda	2014
Evidence of Plasmodium falciparum Malaria Multidrug Resistance to Artemisinin and Piperaquine in Western Cambodia: Dihydroartemisinin-Piperaquine Open-Label Multicenter Clinical Assessment. Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:8 Topics: Adolescent; Adult; Antigens, Bacterial; Antigens, Surface; Antimalarials; Artemisinins; Cambodia; Child; Child, Preschool; Drug Resistance, Multiple; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Plasmodium falciparum; Quinolines; Treatment Failure; Young Adult	2015
Seasonal malaria chemoprevention in an area of extended seasonal transmission in Ashanti, Ghana: an individually randomised clinical trial. Tropical medicine & international health : TM & IH, 2016, Volume: 21, Issue:2 Topics: Amodiaquine; Antimalarials; Artemether; Artemisinins; Chemoprevention; Child, Preschool; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Ghana; Humans; Infant; Infant, Newborn; Lumefantrine; Malaria; Male; Pyrimethamine; Quinolines; Rain; Seasons; Sulfadoxine	2016
Clinical illness and outcomes in Nigerian children with late-appearing anaemia after artemisinin-based combination treatments of uncomplicated falciparum malaria. BMC infectious diseases, 2016, 06-01, Volume: 16 Topics: Adolescent; Amodiaquine; Anemia; Antimalarials; Artemisinins; Child; Child, Preschool; Drug Combinations; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Falciparum; Male; Nigeria; Prognosis; Quinolines; Risk Factors; Time Factors; Treatment Outcome	2016
Pharmacokinetic Interactions between Tafenoquine and Dihydroartemisinin-Piperaquine or Artemether-Lumefantrine in Healthy Adult Subjects. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:12 Topics: Adolescent; Adult; Aged; Aminoquinolines; Antimalarials; Artemisinins; Drug Interactions; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Half-Life; Healthy Volunteers; Humans; Lumefantrine; Malaria, Vivax; Male; Middle Aged; Plasmodium vivax; Quinolines; Young Adult	2016
Triple artemisinin-based combination therapies versus artemisinin-based combination therapies for uncomplicated Plasmodium falciparum malaria: a multicentre, open-label, randomised clinical trial. Lancet (London, England), 2020, 04-25, Volume: 395, Issue:10233 Topics: Adolescent; Adult; Amodiaquine; Anthraquinones; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Drug Resistance; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Plasmodium falciparum; Polymerase Chain Reaction; Quinolines; Treatment Outcome; Young Adult	2020
Mass drug administration for the acceleration of malaria elimination in a region of Myanmar with artemisinin-resistant falciparum malaria: a cluster-randomised trial. The Lancet. Infectious diseases, 2021, Volume: 21, Issue:11 Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; Cluster Analysis; Disease Eradication; Drug Resistance; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Mass Drug Administration; Myanmar; Primaquine; Quinolines; Young Adult	2021
Therapeutic response to artemisinin combination therapies among individuals with Plasmodium falciparum single infection vs mixed Plasmodium species infections: a retrospective posthoc analysis in Kisumu County, western Kenya. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2023, Volume: 132 Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Drug Combinations; Humans; Kenya; Malaria; Malaria, Falciparum; Plasmodium falciparum; Quinolines; Reinfection; Retrospective Studies	2023
Tafenoquine co-administered with dihydroartemisinin-piperaquine for the radical cure of Plasmodium vivax malaria (INSPECTOR): a randomised, placebo-controlled, efficacy and safety study. The Lancet. Infectious diseases, 2023, Volume: 23, Issue:10 Topics: Antimalarials; Artemisinins; Chloroquine; Drug Therapy, Combination; Humans; Malaria; Malaria, Vivax; Plasmodium vivax; Primaquine; Quinolines	2023
Efficacy and safety of pyronaridine-artesunate (PYRAMAX) for the treatment of BMJ open, 2023, 10-09, Volume: 13, Issue:10 Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Clinical Trials, Phase III as Topic; Drug Combinations; Female; Humans; Infant; Malaria; Malaria, Falciparum; Pregnancy; Pregnant Women; Randomized Controlled Trials as Topic; Sub-Saharan African People; Treatment Outcome	2023

Other Studies

115 other study(ies) available for artenimol and artemisinin

Article	Year
Artemisinin Derivatives with Antimelanoma Activity Show Inhibitory Effect against Human DNA Topoisomerase 1. ACS medicinal chemistry letters, 2020, May-14, Volume: 11, Issue:5 Topics:	2020
Synthesis of artemisinin-piperazine-furan ether hybrids and evaluation of in vitro cytotoxic activity. European journal of medicinal chemistry, 2021, Apr-05, Volume: 215 Topics: Antineoplastic Agents; Apoptosis; Artemisinins; Cell Proliferation; Drug Screening Assays, Antitumor; Furans; Humans; MCF-7 Cells; Piperazines	2021
Reinvestigating Old Pharmacophores: Are 4-Aminoquinolines and Tetraoxanes Potential Two-Stage Antimalarials? Journal of medicinal chemistry, 2016, Jan-14, Volume: 59, Issue:1 Topics: Aminoquinolines; Animals; Antimalarials; Drug Evaluation, Preclinical; Ether-A-Go-Go Potassium Channels; Hemin; Hepatocytes; Humans; In Vitro Techniques; Liver; Mice; Microsomes, Liver; Parasite Load; Plasmodium berghei; Plasmodium falciparum; Structure-Activity Relationship; Tetraoxanes	2016
Synthesis of a series of novel dihydroartemisinin monomers and dimers containing chalcone as a linker and their anticancer activity. European journal of medicinal chemistry, 2016, Oct-21, Volume: 122 Topics: Antineoplastic Agents; Apoptosis; Artemisinins; Cell Proliferation; Chalcone; Chemistry Techniques, Synthetic; Dimerization; Drug Design; HL-60 Cells; Humans; Membrane Potential, Mitochondrial	2016
Synthesis of nοvel artemisinin dimers with polyamine linkers and evaluation of their potential as anticancer agents. Bioorganic & medicinal chemistry, 2017, 07-15, Volume: 25, Issue:14 Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Apoptosis; Artemisinins; Chick Embryo; Chickens; Chorioallantoic Membrane; Dimerization; Human Umbilical Vein Endothelial Cells; Humans; MCF-7 Cells; Neovascularization, Physiologic; Polyamines; Reactive Oxygen Species	2017
Synthesis of novel ring-contracted artemisinin dimers with potent anticancer activities. European journal of medicinal chemistry, 2018, Apr-25, Volume: 150 Topics: Animals; Antineoplastic Agents; Apoptosis; Artemisinins; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Dimerization; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Structure; PC12 Cells; Rats; Structure-Activity Relationship	2018
Design, synthesis and biological evaluation of artemisinin derivatives containing fluorine atoms as anticancer agents. Bioorganic & medicinal chemistry letters, 2018, 07-15, Volume: 28, Issue:13 Topics: Antineoplastic Agents; Apoptosis; Artemisinins; Cell Line, Tumor; Drug Design; Drug Screening Assays, Antitumor; Fluorine; G1 Phase Cell Cycle Checkpoints; Humans; Molecular Structure	2018
Access to new highly potent antileukemia, antiviral and antimalarial agents via hybridization of natural products (homo)egonol, thymoquinone and artemisinin. Bioorganic & medicinal chemistry, 2018, 07-23, Volume: 26, Issue:12 Topics: Animals; Anisoles; Antimalarials; Antineoplastic Agents; Antiviral Agents; Artemisinins; Benzofurans; Benzoquinones; Biological Products; Cell Line, Tumor; Cell Survival; Crystallography, X-Ray; Cytomegalovirus; Humans; Molecular Conformation; Plasmodium falciparum	2018
Synthesis of novel S-linked dihydroartemisinin derivatives and evaluation of their anticancer activity. European journal of medicinal chemistry, 2019, Sep-15, Volume: 178 Topics: Antineoplastic Agents; Artemisinins; Cell Cycle; Cell Death; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Docking Simulation; Molecular Structure; PC-3 Cells; Reactive Oxygen Species; Structure-Activity Relationship; Wound Healing	2019
Combating multi-drug resistant malaria parasite by inhibiting falcipain-2 and heme-polymerization: Artemisinin-peptidyl vinyl phosphonate hybrid molecules as new antimalarials. European journal of medicinal chemistry, 2021, Aug-05, Volume: 220 Topics: Antimalarials; Artemisinins; Cysteine Endopeptidases; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Heme; Malaria; Molecular Structure; Organophosphonates; Parasitic Sensitivity Tests; Peptides; Plasmodium falciparum; Polymerization; Structure-Activity Relationship; Vinyl Compounds	2021
Hepatic metabolism of artemisinin drugs--III. Induction of hydrogen peroxide production in rat liver microsomes by artemisinin drugs. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1992, Volume: 101, Issue:2 Topics: Animals; Antimalarials; Artemisinins; Hydrogen Peroxide; Kinetics; Male; Microsomes, Liver; NADP; Rats; Rats, Inbred Strains; Sesquiterpenes	1992
Hemin-catalyzed decomposition of artemisinin (qinghaosu). Biochemical pharmacology, 1992, Apr-15, Volume: 43, Issue:8 Topics: Antimalarials; Artemisinins; Dose-Response Relationship, Drug; Ferric Compounds; Hemin; Oxidation-Reduction; Sesquiterpenes	1992
Effects of artemisinin, dihydroartemisinin and arteether on immune responses of normal mice. International journal of immunopharmacology, 1990, Volume: 12, Issue:4 Topics: Animals; Antibody Formation; Antimalarials; Artemisinins; Carrageenan; Hemolytic Plaque Technique; Hypersensitivity, Delayed; Immunosuppressive Agents; Inflammation; Male; Mice; Sesquiterpenes	1990
Hemolysis induced by artemisinin and its derivatives in vitro. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1986, Volume: 7, Issue:3 Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Erythrocytes; Hemoglobins; Hemolysis; Humans; Pyrans; Sesquiterpenes	1986
The chemotherapy of rodent malaria, XL. The action of artemisinin and related sesquiterpenes. Annals of tropical medicine and parasitology, 1986, Volume: 80, Issue:5 Topics: Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Drug Resistance; Malaria; Male; Mice; Pigments, Biological; Plasmodium berghei; Pyrans; Sesquiterpenes	1986
Determination of dihydroqinghaosu in blood by pyrolysis gas chromatography/mass spectrometry. Analytical chemistry, 1988, Jan-15, Volume: 60, Issue:2 Topics: Animals; Artemisinins; Gas Chromatography-Mass Spectrometry; Male; Rabbits; Sesquiterpenes	1988
In vitro sensitivity of Naegleria fowleri to qinghaosu and dihydroqinghaosu. The Journal of parasitology, 1987, Volume: 73, Issue:2 Topics: Amoeba; Amphotericin B; Animals; Artemisinins; Sesquiterpenes	1987
[Studies on analogs of qinghaosu (artean-nuin, artemisinine). III. The synthesis of diacid esters and mono esters of dihydroqinghaosu]. Yao xue xue bao = Acta pharmaceutica Sinica, 1985, Volume: 20, Issue:2 Topics: Animals; Antimalarials; Artemisinins; Esters; Plasmodium berghei; Sesquiterpenes	1985
The chemotherapy of rodent malaria, XXXIX. Ultrastructural changes following treatment with artemisinine of Plasmodium berghei infection in mice, with observations of the localization of [3H]-dihydroartemisinine in P. falciparum in vitro. Annals of tropical medicine and parasitology, 1985, Volume: 79, Issue:4 Topics: Animals; Antimalarials; Artemisinins; Cell Membrane; Endoplasmic Reticulum; Erythrocytes; Malaria; Mice; Microscopy, Electron; Plasmodium berghei; Plasmodium falciparum; Protein Biosynthesis; Ribosomes; Sesquiterpenes; Time Factors	1985
[Studies on analogs of qinghaosu (artemisinine, arteannuin). IV. Synthesis of derivatives of qinghaosu containing halogen, nitrogen and sulfur heteroatoms]. Yao xue xue bao = Acta pharmaceutica Sinica, 1985, Volume: 20, Issue:5 Topics: Animals; Antimalarials; Artemisinins; Mice; Sesquiterpenes	1985
Rapid action of Qinghaosu and related drugs on incorporation of [3H]isoleucine by Plasmodium falciparum in vitro. Biochemical pharmacology, 1983, Sep-01, Volume: 32, Issue:17 Topics: Animals; Antimalarials; Artemether; Artemisinins; Isoleucine; Kinetics; Plasmodium falciparum; Protein Biosynthesis; Pyrans; Sesquiterpenes; Tritium	1983
Effects of qinghaosu and related compounds on incorporation of [G-3H] hypoxanthine by Plasmodium falciparum in vitro. Transactions of the Royal Society of Tropical Medicine and Hygiene, 1983, Volume: 77, Issue:4 Topics: Animals; Antimalarials; Artemether; Artemisinins; Hypoxanthine; Hypoxanthines; Plasmodium falciparum; Pyrans; Sesquiterpenes; Time Factors	1983
Antimalarial activity of dihydroartemisinin derivatives by transdermal application. The American journal of tropical medicine and hygiene, 1994, Volume: 50, Issue:6 Topics: Administration, Cutaneous; Animals; Antimalarials; Artemether; Artemisinins; Gels; Malaria; Mice; Plasmodium berghei; Sesquiterpenes; Structure-Activity Relationship	1994
Clinical trials of artemisinin and its derivatives in the treatment of malaria in China. Transactions of the Royal Society of Tropical Medicine and Hygiene, 1994, Volume: 88 Suppl 1 Topics: Antimalarials; Antiprotozoal Agents; Artemisinins; Artesunate; China; Clinical Trials as Topic; Humans; Injections, Intramuscular; Injections, Intravenous; Malaria, Cerebral; Malaria, Falciparum; Sesquiterpenes; Suppositories; Tablets	1994
Comparison of in vivo and in vitro antimalarial activity of artemisinin, dihydroartemisinin and sodium artesunate in the Plasmodium berghei-rodent model. International journal for parasitology, 1994, Volume: 24, Issue:4 Topics: Animals; Antimalarials; Artemisinins; Artesunate; Malaria; Mice; Plasmodium berghei; Rats; Rats, Wistar; Sesquiterpenes	1994
[Pharmacokinetics of dihydroqinghaosu in human volunteers and comparison with qinghaosu]. Yao xue xue bao = Acta pharmaceutica Sinica, 1993, Volume: 28, Issue:5 Topics: Administration, Oral; Adult; Artemisinins; Biological Availability; Estrenes; Humans; Male; Radioimmunoassay; Sesquiterpenes; Suppositories; Tablets	1993
Artemisinin and its derivatives enhance T lymphocyte-mediated immune responses in normal mice and accelerate immunoreconstitution of mice with syngeneic bone marrow transplantation. Clinical immunology and immunopathology, 1993, Volume: 69, Issue:2 Topics: Adjuvants, Immunologic; Analysis of Variance; Animals; Antimalarials; Artemisinins; Artesunate; B-Lymphocytes; Bone Marrow Transplantation; Concanavalin A; DNA; Dose-Response Relationship, Immunologic; Female; Hypersensitivity, Delayed; Immunity, Cellular; Interleukin-2; Lipopolysaccharides; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Sesquiterpenes; Spleen; T-Lymphocytes	1993
Structure-activity relationships of the antimalarial agent artemisinin. 2. Effect of heteroatom substitution at O-11: synthesis and bioassay of N-alkyl-11-aza-9-desmethylartemisinins. Journal of medicinal chemistry, 1995, Dec-22, Volume: 38, Issue:26 Topics: Animals; Antimalarials; Artemisinins; Drug Evaluation, Preclinical; Drugs, Chinese Herbal; Erythrocytes; Humans; Molecular Structure; Plasmodium falciparum; Sesquiterpenes; Structure-Activity Relationship	1995
In vitro stage-specific sensitivity of Plasmodium falciparum to quinine and artemisinin drugs. International journal for parasitology, 1996, Volume: 26, Issue:5 Topics: Adult; Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Drug Evaluation, Preclinical; Drug Resistance; Humans; In Vitro Techniques; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Quinine; Sesquiterpenes	1996
In vitro susceptibility of Plasmodium falciparum isolates in Vietnam to artemisinin derivatives and other antimalarials. Acta tropica, 1997, Volume: 63, Issue:2-3 Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Mefloquine; Microbial Sensitivity Tests; Plasmodium falciparum; Quinine; Sesquiterpenes; Vietnam	1997
Antimalarial activity of new dihydroartemisinin derivatives. 7. 4-(p-substituted phenyl)-4(R or S)-[10(alpha or beta)-dihydroartemisininoxy]butyric acids. Journal of medicinal chemistry, 1997, Apr-25, Volume: 40, Issue:9 Topics: Animals; Antimalarials; Artemisinins; Drug Design; Female; Magnetic Resonance Spectroscopy; Malaria; Mice; Molecular Conformation; Molecular Structure; Parasitemia; Plasmodium berghei; Plasmodium falciparum; Sesquiterpenes; Solubility	1997
Validation of an improved reversed-phase high-performance liquid chromatography assay with reductive electrochemical detection for the determination of artemisinin derivatives in man. Therapeutic drug monitoring, 1998, Volume: 20, Issue:1 Topics: Antimalarials; Artemisinins; Chromatography, High Pressure Liquid; Electrochemistry; Humans; Sesquiterpenes	1998
Selection and characterization of Toxoplasma gondii mutants resistant to artemisinin. The Journal of infectious diseases, 1998, Volume: 177, Issue:4 Topics: Animals; Antimalarials; Antiprotozoal Agents; Artemether; Artemisinins; Drug Resistance; Ethyl Methanesulfonate; Female; Humans; Methylnitronitrosoguanidine; Mice; Mice, Inbred ICR; Mutagenesis; Sesquiterpenes; Toxoplasma; Toxoplasmosis, Animal	1998
The Plasmodium falciparum translationally controlled tumor protein homolog and its reaction with the antimalarial drug artemisinin. The Journal of biological chemistry, 1998, Jun-26, Volume: 273, Issue:26 Topics: Amino Acid Sequence; Animals; Antimalarials; Artemisinins; Biomarkers, Tumor; Calcium-Binding Proteins; Cloning, Molecular; Drugs, Chinese Herbal; Erythrocytes; Humans; Models, Chemical; Molecular Sequence Data; Plasmodium falciparum; Protein Binding; Recombinant Proteins; Sequence Alignment; Sesquiterpenes; Tumor Protein, Translationally-Controlled 1	1998
In vitro susceptibility of African Plasmodium falciparum isolates to dihydroartemisinin and the risk factors for resistance to qinghaosu. Medecine tropicale : revue du Corps de sante colonial, 1998, Volume: 58, Issue:3 Suppl Topics: Africa; Animals; Antimalarials; Artemisinins; Chloroquine; Cross Reactions; Drug Evaluation, Preclinical; Drug Resistance; France; Humans; Malaria, Falciparum; Mefloquine; Phenanthrenes; Plasmodium falciparum; Sesquiterpenes; Travel	1998
In vitro neurotoxicity of artemisinin derivatives. Medecine tropicale : revue du Corps de sante colonial, 1998, Volume: 58, Issue:3 Suppl Topics: Animals; Antimalarials; Artemether; Artemisinins; Cell Differentiation; Central Nervous System Diseases; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Mice; Microscopy, Electron; Neuroblastoma; Neurons; Reproducibility of Results; Sesquiterpenes; Tumor Cells, Cultured	1998
The development of an immunoassay for the detection of artemisinin compounds in urine. The American journal of tropical medicine and hygiene, 1999, Volume: 61, Issue:3 Topics: Adult; Antibodies, Monoclonal; Antimalarials; Artemisinins; Artesunate; Cross Reactions; Enzyme-Linked Immunosorbent Assay; Humans; Sesquiterpenes	1999
Inoculum effect leads to overestimation of in vitro resistance for artemisinin derivatives and standard antimalarials: a Gambian field study. Parasitology, 1999, Volume: 119 ( Pt 5) Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Gambia; Hematocrit; Humans; Malaria, Falciparum; Mefloquine; Parasitemia; Phenanthrenes; Plasmodium falciparum; Quinine; Scintillation Counting; Sensitivity and Specificity; Sesquiterpenes	1999
The role of glutathione in the neurotoxicity of artemisinin derivatives in vitro. Biochemical pharmacology, 2001, Feb-15, Volume: 61, Issue:4 Topics: Animals; Antimalarials; Antimetabolites; Antioxidants; Artemether; Artemisinins; Buthionine Sulfoximine; Drug Interactions; Glutathione; Hemin; Humans; Mice; Neurites; Sesquiterpenes; Tumor Cells, Cultured	2001
Antimalarial activity of azithromycin, artemisinin and dihydroartemisinin in fresh isolates of Plasmodium falciparum in Thailand. Acta tropica, 2001, Sep-01, Volume: 80, Issue:1 Topics: Animals; Anti-Bacterial Agents; Antimalarials; Artemisinins; Azithromycin; Dose-Response Relationship, Drug; Humans; Parasitic Sensitivity Tests; Plasmodium falciparum; Sesquiterpenes; Thailand	2001
The development of new antimalarial drugs: qinghaosu and dihydro-qinghaosu. Chinese medical journal, 1999, Volume: 112, Issue:11 Topics: Animals; Antimalarials; Artemether; Artemisia; Artemisinins; Artesunate; Drugs, Chinese Herbal; Humans; Sesquiterpenes	1999
Modulation of multidrug resistance by artemisinin, artesunate and dihydroartemisinin in K562/adr and GLC4/adr resistant cell lines. Biological & pharmaceutical bulletin, 2002, Volume: 25, Issue:12 Topics: Artemisinins; Artesunate; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line; Drug Resistance, Multiple; Humans; K562 Cells; Membrane Potentials; Mitochondria; Multidrug Resistance-Associated Proteins; Sesquiterpenes; Tumor Cells, Cultured	2002
Artemisinin antimalarials do not inhibit hemozoin formation. Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:3 Topics: Antimalarials; Artemisinins; Heme; Hemeproteins; Hemin; Sesquiterpenes	2003
Plasmodium falciparum-based bioassay for measurement of artemisinin derivatives in plasma or serum. Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:3 Topics: Animals; Antimalarials; Artemisinins; Artesunate; Biological Assay; Biotransformation; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Electrochemistry; Hot Temperature; Humans; In Vitro Techniques; Macaca mulatta; Malaria, Falciparum; Plasmodium falciparum; Reproducibility of Results; Sesquiterpenes	2004
In vitro interactions of Aspilia africana (Pers.) C.D. Adams, a traditional antimalarial medicinal plant, with artemisinin against Plasmodium falciparum. Journal of ethnopharmacology, 2005, Nov-14, Volume: 102, Issue:2 Topics: Animals; Antimalarials; Artemisinins; Asteraceae; Drug Interactions; Erythrocytes; India; Medicine, Traditional; Plant Extracts; Plasmodium falciparum; Sesquiterpenes	2005
In vitro and in vivo treatments of echinococcus protoscoleces and metacestodes with artemisinin and artemisinin derivatives. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:9 Topics: Albendazole; Animals; Anti-Infective Agents; Antiparasitic Agents; Artemisinins; Drug Therapy, Combination; Echinococcosis; Echinococcus granulosus; Echinococcus multilocularis; Humans; Larva; Mice; Mice, Inbred BALB C; Nitro Compounds; Parasitic Sensitivity Tests; Thiazoles; Treatment Outcome	2008
Experimental therapy of hepatoma with artemisinin and its derivatives: in vitro and in vivo activity, chemosensitization, and mechanisms of action. Clinical cancer research : an official journal of the American Association for Cancer Research, 2008, Sep-01, Volume: 14, Issue:17 Topics: Animals; Antineoplastic Agents; Artemether; Artemisinins; Artesunate; Carcinoma, Hepatocellular; Cell Cycle; Cell Line, Tumor; Female; Gene Expression Regulation, Neoplastic; Humans; Liver; Liver Neoplasms; Mice; Mice, Nude; Xenograft Model Antitumor Assays	2008
Artemisinin-transferrin conjugate retards growth of breast tumors in the rat. Anticancer research, 2009, Volume: 29, Issue:10 Topics: Adenocarcinoma; Animals; Artemisinins; Female; Injections, Intravenous; Mammary Neoplasms, Experimental; Random Allocation; Rats; Rats, Inbred F344; Transferrin	2009
Novel polymorphisms in Plasmodium falciparum ABC transporter genes are associated with major ACT antimalarial drug resistance. PloS one, 2011, Volume: 6, Issue:5 Topics: Animals; Antimalarials; Artemisinins; ATP-Binding Cassette Transporters; Base Sequence; Drug Resistance; Ethanolamines; Fluorenes; Gene Frequency; Genotype; Haplotypes; Humans; Inhibitory Concentration 50; Lumefantrine; Malaria, Falciparum; Mefloquine; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins	2011
Cytotoxicity of ethanolic extracts of Artemisia annua to Molt-4 human leukemia cells. Planta medica, 2011, Volume: 77, Issue:16 Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Artemisia annua; Artemisinins; Brazil; Cell Death; Cell Line, Tumor; China; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Free Radical Scavengers; Humans; Lethal Dose 50; Leukocytes; Medicine, Chinese Traditional; Plant Leaves; Plants, Medicinal; Time Factors	2011
Artemisinin activity against Plasmodium falciparum requires hemoglobin uptake and digestion. Proceedings of the National Academy of Sciences of the United States of America, 2011, Jul-12, Volume: 108, Issue:28 Topics: Animals; Antimalarials; Artemisinins; Biological Transport, Active; Cysteine Endopeptidases; Endocytosis; Erythrocytes; Gene Deletion; Genes, Protozoan; Hemoglobins; Host-Parasite Interactions; Humans; Malaria, Falciparum; Parasitemia; Plasmodium falciparum	2011
Administrative practices of health professionals and use of artesunate-amodiaquine by community members for treating uncomplicated malaria in southern Ghana: implications for artemisinin-based combination therapy deployment. Tropical medicine & international health : TM & IH, 2011, Volume: 16, Issue:10 Topics: Adolescent; Adult; Aged; Amodiaquine; Antimalarials; Artemisinins; Child; Child, Preschool; Community-Based Participatory Research; Drug Combinations; Drug Resistance, Microbial; Drug Therapy, Combination; Drug Utilization; Female; Ghana; Health Care Surveys; Humans; Infant; Male; Middle Aged; Nurses; Pharmacists; Pharmacy Technicians; Physicians; Practice Patterns, Physicians'; Rural Population; Surveys and Questionnaires; Urban Population	2011
Rapid identification of phase I and II metabolites of artemisinin antimalarials using LTQ-Orbitrap hybrid mass spectrometer in combination with online hydrogen/deuterium exchange technique. Journal of mass spectrometry : JMS, 2011, Volume: 46, Issue:8 Topics: Animals; Antimalarials; Artemisinins; Bile; Biotransformation; Chromatography, Liquid; Deuterium Exchange Measurement; Humans; Hydroxylation; Male; Mass Spectrometry; Microsomes, Liver; Rats; Rats, Wistar	2011
Monitoring of artemisinin, dihydroartemisinin, and artemether in environmental matrices using high-performance liquid chromatography-tandem mass spectrometry (LC-MS/MS). Journal of agricultural and food chemistry, 2011, Nov-09, Volume: 59, Issue:21 Topics: Artemether; Artemisia annua; Artemisinins; Chromatography, High Pressure Liquid; Kenya; Plant Extracts; Soil; Tandem Mass Spectrometry	2011
Metabolite identification of artemether by data-dependent accurate mass spectrometric analysis using an LTQ-Orbitrap hybrid mass spectrometer in combination with the online hydrogen/deuterium exchange technique. Rapid communications in mass spectrometry : RCM, 2011, Nov-15, Volume: 25, Issue:21 Topics: Animals; Antimalarials; Artemether; Artemisinins; Bile; Chromatography, Liquid; Deuterium Exchange Measurement; Hydroxylation; Male; Mass Spectrometry; Methylation; Microsomes, Liver; Rats; Rats, Wistar; Tandem Mass Spectrometry	2011
Effects of artemisinin dimers on rat breast cancer cells in vitro and in vivo. Anticancer research, 2011, Volume: 31, Issue:12 Topics: Alcohols; Animals; Anti-Infective Agents; Antioxidants; Artemisinins; Cell Line, Tumor; Dimerization; Female; Humans; In Vitro Techniques; Inhibitory Concentration 50; Mammary Neoplasms, Animal; Models, Chemical; Rats; Rats, Inbred F344; Time Factors	2011
Dihydroartemisinin inhibits the human erythroid cell differentiation by altering the cell cycle. Toxicology, 2012, Oct-09, Volume: 300, Issue:1-2 Topics: Artemisinins; Cell Cycle; Cell Differentiation; Erythroid Cells; Flow Cytometry; Humans; K562 Cells; Reverse Transcriptase Polymerase Chain Reaction; Structure-Activity Relationship	2012
Evaluation of P450 inhibition and induction by artemisinin antimalarials in human liver microsomes and primary human hepatocytes. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:9 Topics: Antimalarials; Artemisinins; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cells, Cultured; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Induction; Enzyme Inhibitors; Hepatocytes; Humans; Kinetics; Liver; Microsomes, Liver; Models, Biological; Oxidoreductases, N-Demethylating; Primary Cell Culture; Recombinant Proteins; RNA, Messenger	2012
Dihydroartemisinin ameliorates inflammatory disease by its reciprocal effects on Th and regulatory T cell function via modulating the mammalian target of rapamycin pathway. Journal of immunology (Baltimore, Md. : 1950), 2012, Nov-01, Volume: 189, Issue:9 Topics: Amino Acid Sequence; Animals; Artemisinins; Encephalomyelitis, Autoimmune, Experimental; Inflammation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Molecular Sequence Data; Signal Transduction; T-Lymphocytes, Helper-Inducer; T-Lymphocytes, Regulatory; TOR Serine-Threonine Kinases	2012
Effect of single nucleotide polymorphisms in cytochrome P450 isoenzyme and N-acetyltransferase 2 genes on the metabolism of artemisinin-based combination therapies in malaria patients from Cambodia and Tanzania. Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:2 Topics: Alleles; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Arylamine N-Acetyltransferase; Base Sequence; Cambodia; Cytochrome P-450 Enzyme System; Drug Combinations; Ethanolamines; Fluorenes; Gene Frequency; Humans; Isoenzymes; Malaria; Mefloquine; Pharmacogenetics; Polymorphism, Single Nucleotide; Quinolines; Sequence Analysis, DNA; Tanzania	2013
[Anti-inflammatory effect and mechanism of artemisinin and dihydroartemisinin]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2012, Volume: 37, Issue:17 Topics: Animals; Anti-Inflammatory Agents; Artemisinins; Cell Line; Gene Expression; Inflammation Mediators; Interleukin-6; Macrophages; Mice; Nitric Oxide; Tumor Necrosis Factor-alpha	2012
Differential interactions of the broad spectrum drugs artemisinin, dihydroartemisinin and artesunate with serum albumin. Phytomedicine : international journal of phytotherapy and phytopharmacology, 2013, Aug-15, Volume: 20, Issue:11 Topics: Animals; Artemisinins; Artesunate; Cattle; Drug Therapy, Combination; Hydrophobic and Hydrophilic Interactions; Malaria; Protein Binding; Serum Albumin	2013
Plasmodium falciparum Polymorphisms associated with ex vivo drug susceptibility and clinical effectiveness of artemisinin-based combination therapies in Benin. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:1 Topics: Amodiaquine; Antimalarials; Artemisinins; Drug Combinations; Ethanolamines; Female; Fluorenes; Humans; Inhibitory Concentration 50; Lumefantrine; Male; Mefloquine; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins; Pyrimethamine; Quinine; Sulfadoxine	2014
Evidence for pyronaridine as a highly effective partner drug for treatment of artemisinin-resistant malaria in a rodent model. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:1 Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Artesunate; Drug Combinations; Drug Resistance; Female; Flow Cytometry; Malaria, Falciparum; Mefloquine; Mice; Naphthyridines	2014
Effects of artemisinin antimalarials on Cytochrome P450 enzymes in vitro using recombinant enzymes and human liver microsomes: potential implications for combination therapies. Xenobiotica; the fate of foreign compounds in biological systems, 2014, Volume: 44, Issue:7 Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C19; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Evaluation, Preclinical; Drug Interactions; Humans; Inhibitory Concentration 50; Microsomes, Liver; Recombinant Proteins; Tandem Mass Spectrometry	2014
Competition between Plasmodium falciparum strains in clinical infections during in vitro culture adaptation. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, 2014, Volume: 24 Topics: Alleles; Antigens, Protozoan; Antimalarials; Artemisinins; DNA, Protozoan; Drug Resistance; Genetic Variation; Genotype; Humans; Malaria, Falciparum; Merozoite Surface Protein 1; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Protozoan Proteins; Quinolines; Tetrahydrofolate Dehydrogenase	2014
Comparative studies on the interactions of dihydroartemisinin and artemisinin with bovine serum albumin using spectroscopic methods. Luminescence : the journal of biological and chemical luminescence, 2014, Volume: 29, Issue:8 Topics: Artemisinins; Binding Sites; Energy Transfer; Fluorescence; Imaging, Three-Dimensional; Light; Protein Conformation; Scattering, Radiation; Serum Albumin, Bovine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Temperature; Thermodynamics	2014
Flow cytometry-based analysis of artemisinin-resistant Plasmodium falciparum in the ring-stage survival assay. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:8 Topics: Antimalarials; Artemisinins; Biological Assay; Cell Survival; Erythrocytes; Flow Cytometry; Fluorescent Dyes; Half-Life; Humans; Life Cycle Stages; Parasitic Sensitivity Tests; Plasmodium falciparum; Staining and Labeling	2014
Fatty acid synthesis and pyruvate metabolism pathways remain active in dihydroartemisinin-induced dormant ring stages of Plasmodium falciparum. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:8 Topics: Acetyl-CoA Carboxylase; Antimalarials; Apicoplasts; Artemisinins; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Enzyme Inhibitors; Erythrocytes; Fatty Acids; Gene Expression Regulation; Humans; Life Cycle Stages; Metabolic Networks and Pathways; Mitochondria; Mitochondrial Proteins; Plasmodium falciparum; Protozoan Proteins; Pyruvates; Transcription, Genetic	2014
Development of a dihydroartemisinin-resistant Molt-4 leukemia cell line. Anticancer research, 2014, Volume: 34, Issue:6 Topics: Antimalarials; Artemisinins; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Humans; Leukemia; Transferrin; Tumor Cells, Cultured	2014
Interspecies allometric scaling of antimalarial drugs and potential application to pediatric dosing. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:10 Topics: Age Factors; Antimalarials; Artemether; Artemisinins; Artesunate; Child; Child, Preschool; Female; Humans; Male; Models, Theoretical	2014
Inhibition of metalloproteinase-9 secretion and gene expression by artemisinin derivatives. Acta tropica, 2014, Volume: 140 Topics: Artemisinins; Artesunate; Cytokines; Gene Expression Regulation; Humans; Inflammation Mediators; Malaria, Cerebral; Malaria, Falciparum; Matrix Metalloproteinase 9; Monocytes; Plasmodium falciparum; Polymerase Chain Reaction; RNA, Messenger	2014
Design, synthesis, and biological evaluation of artemisinin-indoloquinoline hybrids as potent antiproliferative agents. Molecules (Basel, Switzerland), 2014, Nov-18, Volume: 19, Issue:11 Topics: Animals; Antineoplastic Agents; Artemisinins; BALB 3T3 Cells; Cell Line; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; HCT116 Cells; Humans; Mice; Quinolines; Structure-Activity Relationship	2014
Contrasting benefits of different artemisinin combination therapies as first-line malaria treatments using model-based cost-effectiveness analysis. Nature communications, 2014, Nov-26, Volume: 5 Topics: Africa; Antimalarials; Artemisinins; Cost-Benefit Analysis; Ethanolamines; Fluorenes; Humans; Lumefantrine; Malaria, Falciparum; Models, Theoretical; Quinolines; Seasons	2014
DNA damage in dihydroartemisinin-resistant Molt-4 cells. Anticancer research, 2015, Volume: 35, Issue:3 Topics: Antineoplastic Agents; Artemisinins; Cell Line, Tumor; Comet Assay; DNA Damage; Drug Resistance, Neoplasm; Humans; Transferrin	2015
A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria. Nature, 2015, Apr-30, Volume: 520, Issue:7549 Topics: Antimalarials; Artemisinins; Drug Resistance; Genome-Wide Association Study; Malaria, Falciparum; Models, Molecular; Mutation; Phosphatidylinositol 3-Kinase; Phosphatidylinositol Phosphates; Phosphoinositide-3 Kinase Inhibitors; Plasmodium falciparum; Protozoan Proteins	2015
Ex Vivo Drug Susceptibility Testing and Molecular Profiling of Clinical Plasmodium falciparum Isolates from Cambodia from 2008 to 2013 Suggest Emerging Piperaquine Resistance. Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:8 Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Cambodia; Chloroquine; Drug Resistance; Female; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Male; Mefloquine; Membrane Transport Proteins; Middle Aged; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines; Young Adult	2015
Artemisinin resistance at the China-Myanmar border and association with mutations in the K13 propeller gene. Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:11 Topics: Artemisinins; China; Drug Resistance, Multiple; Genotype; Malaria, Falciparum; Mutation; Myanmar; Plasmodium falciparum; Quinolines	2015
Genetic Transformation of Artemisia carvifolia Buch with rol Genes Enhances Artemisinin Accumulation. PloS one, 2015, Volume: 10, Issue:10 Topics: Agrobacterium tumefaciens; Antimalarials; Artemether; Artemisia annua; Artemisinins; Artesunate; Base Sequence; Biosynthetic Pathways; Gene Expression Regulation, Plant; Molecular Sequence Data; Plant Proteins; Plants, Genetically Modified; Transformation, Genetic; Trichomes	2015
Optimum population-level use of artemisinin combination therapies: a modelling study. The Lancet. Global health, 2015, Volume: 3, Issue:12 Topics: Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Drug Administration Schedule; Drug Combinations; Drug Resistance; Ethanolamines; Fluorenes; Humans; Malaria, Falciparum; Models, Biological; Plasmodium falciparum; Quinolines; Treatment Failure	2015
Safety of artemisinins in first trimester of prospectively followed pregnancies: an observational study. The Lancet. Infectious diseases, 2016, Volume: 16, Issue:5 Topics: Abortion, Spontaneous; Adolescent; Adult; Antimalarials; Artemisinins; Female; Humans; Malaria, Falciparum; Malaria, Vivax; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Quinine; Thailand	2016
UK malaria treatment guidelines 2016. The Journal of infection, 2016, Volume: 72, Issue:6 Topics: Adult; Antimalarials; Artemisinins; Artesunate; Breast Feeding; Child; Child, Preschool; Female; Humans; Malaria; Malaria, Falciparum; Malaria, Vivax; Plasmodium falciparum; Plasmodium vivax; Pregnancy; Pregnancy Complications, Parasitic; Primaquine; Travel	2016
IR and Vibrational Circular Dichroism Spectroscopy of Matrine- and Artemisinin-Type Herbal Products: Stereochemical Characterization and Solvent Effects. Journal of natural products, 2016, Apr-22, Volume: 79, Issue:4 Topics: Alkaloids; Artemisinins; Circular Dichroism; Drugs, Chinese Herbal; Hydrogen Bonding; Malaria; Matrines; Molecular Structure; Quinolizines; Sophora	2016
Comparison of the Exposure Time Dependence of the Activities of Synthetic Ozonide Antimalarials and Dihydroartemisinin against K13 Wild-Type and Mutant Plasmodium falciparum Strains. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:8 Topics: Antimalarials; Artemisinins; Heterocyclic Compounds; Parasitic Sensitivity Tests; Plasmodium falciparum	2016
Highly active ozonides selected against drug resistant malaria. Memorias do Instituto Oswaldo Cruz, 2016, Jun-07, Volume: 0 Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Disease Models, Animal; Female; Humans; Malaria, Falciparum; Mefloquine; Mice; Parasitemia; Plasmodium falciparum	2016
Correlation between Cyclin Dependent Kinases and Artemisinin-Induced Dormancy in Plasmodium falciparum In Vitro. PloS one, 2016, Volume: 11, Issue:6 Topics: Animals; Artemisinins; Cyclin-Dependent Kinases; Cyclins; Genes, Protozoan; Life Cycle Stages; Parasitemia; Parasites; Plasmodium falciparum; Protein Kinase Inhibitors; Transcription, Genetic	2016
Assessing the asymptomatic reservoir and dihydroartemisinin-piperaquine effectiveness in a low transmission setting threatened by artemisinin resistant Plasmodium falciparum. Malaria journal, 2016, 09-01, Volume: 15, Issue:1 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemisinins; Asymptomatic Diseases; Cambodia; Child; Child, Preschool; Cross-Sectional Studies; Drug Resistance; Female; Humans; Incidence; Infant; Infant, Newborn; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Prevalence; Quinolines; Real-Time Polymerase Chain Reaction; Treatment Outcome; Young Adult	2016
Endoperoxide Drug Cross-Resistance Patterns for Plasmodium falciparum Exhibiting an Artemisinin Delayed-Clearance Phenotype. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:11 Topics: Adamantane; Antimalarials; Artemether; Artemisinins; Dose-Response Relationship, Drug; Drug Resistance; Heterocyclic Compounds, 1-Ring; Inactivation, Metabolic; Lethal Dose 50; Microbial Sensitivity Tests; Peroxides; Plasmodium falciparum; Spiro Compounds	2016
Microbial transformation of the antimalarial sesquiterpene endoperoxide dihydroartemisinin. Natural product research, 2017, Volume: 31, Issue:8 Topics: Absidia; Antimalarials; Artemisinins; Biotransformation; Molecular Structure; Oxidation-Reduction; Penicillium chrysogenum	2017
Influence of the The American journal of tropical medicine and hygiene, 2017, Volume: 96, Issue:3 Topics: Alleles; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Gene Dosage; Genotyping Techniques; Inhibitory Concentration 50; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins; Quinolines; Thailand	2017
Application of the Triazolization Reaction to Afford Dihydroartemisinin Derivatives with Anti-HIV Activity. Molecules (Basel, Switzerland), 2017, Feb-17, Volume: 22, Issue:2 Topics: Amines; Anti-HIV Agents; Artemisinins; Catalysis; Cell Line; HIV; Humans; Inhibitory Concentration 50; Ketones; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Molecular Structure; Triazoles	2017
A Variant PfCRT Isoform Can Contribute to mBio, 2017, 05-09, Volume: 8, Issue:3 Topics: Antimalarials; Artemisinins; Cambodia; Drug Resistance; Gene Editing; Humans; Lethal Dose 50; Malaria, Falciparum; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Mutation; Plasmodium falciparum; Protein Isoforms; Protozoan Proteins; Quinolines	2017
The Plasmodium PI(4)K inhibitor KDU691 selectively inhibits dihydroartemisinin-pretreated Plasmodium falciparum ring-stage parasites. Scientific reports, 2017, 05-24, Volume: 7, Issue:1 Topics: Animals; Antimalarials; Artemisinins; Cell Cycle Checkpoints; Drug Resistance; Humans; Malaria, Falciparum; Plasmodium falciparum; Pyrazines	2017
Impact of Intermittent Preventive Treatment During Pregnancy on Plasmodium falciparum Drug Resistance-Mediating Polymorphisms in Uganda. The Journal of infectious diseases, 2017, 11-15, Volume: 216, Issue:8 Topics: Antimalarials; Artemisinins; Drug Combinations; Drug Resistance; Female; Humans; Malaria, Falciparum; Plasmodium falciparum; Polymorphism, Genetic; Pregnancy; Pyrimethamine; Quinolines; Sulfadoxine	2017
Comparison of the Pharmacokinetics and Ex Vivo Antimalarial Activities of Artesunate-Amodiaquine and Artemisinin-Piperaquine in Healthy Volunteers for Preselection Malaria Therapy. The American journal of tropical medicine and hygiene, 2018, Volume: 99, Issue:1 Topics: Amodiaquine; Antimalarials; Area Under Curve; Artemisinins; Biotransformation; Drug Administration Schedule; Drug Combinations; Half-Life; Healthy Volunteers; Humans; Malaria, Falciparum; Male; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines; Tablets; Young Adult	2018
Investigating the Efficacy of Triple Artemisinin-Based Combination Therapies for Treating Plasmodium falciparum Malaria Patients Using Mathematical Modeling. Antimicrobial agents and chemotherapy, 2018, Volume: 62, Issue:11 Topics: Antimalarials; Artemisinins; Asia, Southeastern; Drug Therapy, Combination; Humans; Malaria, Falciparum; Mefloquine; Models, Theoretical; Plasmodium falciparum; Quinolines	2018
Comparison of in vitro/in vivo blood distribution and pharmacokinetics of artemisinin, artemether and dihydroartemisinin in rats. Journal of pharmaceutical and biomedical analysis, 2019, Jan-05, Volume: 162 Topics: Administration, Oral; Animals; Antimalarials; Artemether; Artemisinins; Chromatography, Liquid; Drug Monitoring; Injections, Intravenous; Male; Rats, Sprague-Dawley; Tandem Mass Spectrometry; Tissue Distribution	2019
Evaluation of the effects on the QT-interval of 4 artemisinin-based combination therapies with a correction-free and heart rate-free method. Scientific reports, 2019, 01-29, Volume: 9, Issue:1 Topics: Adolescent; Amodiaquine; Antimalarials; Arrhythmias, Cardiac; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Child, Preschool; Drug Combinations; Ethanolamines; Female; Fluorenes; Heart Rate; Humans; Long QT Syndrome; Malaria; Malaria, Falciparum; Male; Quinolines; Young Adult	2019
Artemisinin compounds sensitize cancer cells to ferroptosis by regulating iron homeostasis. Cell death and differentiation, 2020, Volume: 27, Issue:1 Topics: Animals; Antineoplastic Agents; Artemisinins; Autophagy; Cell Line, Tumor; Female; Ferroptosis; Homeostasis; Humans; Iron; Iron-Regulatory Proteins; Lysosomes; Mice, Nude; Neoplasms; Response Elements	2020
Artemisinin and its derivatives prevent Helicobacter pylori-induced gastric carcinogenesis via inhibition of NF-κB signaling. Phytomedicine : international journal of phytotherapy and phytopharmacology, 2019, Volume: 63 Topics: Animals; Anticarcinogenic Agents; Artemisinins; Artesunate; Bacterial Adhesion; Cell Line, Tumor; Cytokines; Helicobacter Infections; Helicobacter pylori; Humans; Mice, Inbred C57BL; Microbial Sensitivity Tests; NF-kappa B; Reactive Oxygen Species; Stomach Neoplasms	2019
Efavirenz-Based Antiretroviral Therapy Reduces Artemether-Lumefantrine Exposure for Malaria Treatment in HIV-Infected Pregnant Women. Journal of acquired immune deficiency syndromes (1999), 2020, 02-01, Volume: 83, Issue:2 Topics: Adolescent; Adult; Alkynes; Anti-HIV Agents; Anti-Retroviral Agents; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Benzoxazines; Cyclopropanes; Drug Combinations; Drug Interactions; Female; HIV Infections; Humans; Lumefantrine; Malaria; Malaria, Falciparum; Pregnancy; Prospective Studies; Uganda; Young Adult	2020
The extended recovery ring-stage survival assay provides a superior association with patient clearance half-life and increases throughput. Malaria journal, 2020, Jan-31, Volume: 19, Issue:1 Topics: Antimalarials; Artemisinins; Benzothiazoles; Diamines; Drug Resistance; Erythrocytes; Flow Cytometry; Fluorescent Dyes; Half-Life; Humans; Malaria, Falciparum; Organic Chemicals; Parasitemia; Plasmodium falciparum; Povidone; Quinolines; Real-Time Polymerase Chain Reaction; Silicon Dioxide	2020
Role of Plasmodium falciparum Kelch 13 Protein Mutations in P. falciparum Populations from Northeastern Myanmar in Mediating Artemisinin Resistance. mBio, 2020, 02-25, Volume: 11, Issue:1 Topics: Antimalarials; Artemisinins; Asia, Southeastern; Drug Resistance; Humans; Malaria, Falciparum; Mutation; Organisms, Genetically Modified; Plasmodium falciparum; Protozoan Proteins	2020
Genetic screens reveal a central role for heme metabolism in artemisinin susceptibility. Nature communications, 2020, 09-23, Volume: 11, Issue:1 Topics: Antimalarials; Artemisinins; Clustered Regularly Interspaced Short Palindromic Repeats; Drug Resistance; Gene Knockout Techniques; Genetic Testing; Heme; Humans; Malaria, Falciparum; Membrane Transport Proteins; Mutation; Plasmodium falciparum; Protozoan Proteins; Toxoplasma	2020
Leishmania amazonensis response to artemisinin and derivatives. Parasitology international, 2021, Volume: 80 Topics: Animals; Artemether; Artemisinins; Artesunate; Disease Models, Animal; Female; Leishmania mexicana; Mice; Mice, Inbred BALB C; Parasite Load; Trypanocidal Agents	2021
Dihydroartemisinin, an active metabolite of artemisinin, interferes with Leishmania braziliensis mitochondrial bioenergetics and survival. Parasitology research, 2021, Volume: 120, Issue:2 Topics: Animals; Antiprotozoal Agents; Artemisinins; Energy Metabolism; Hydrogen Peroxide; Leishmania braziliensis; Macrophages; Mitochondria; Succinates	2021
Artemisia annua L. extracts inhibit the in vitro replication of SARS-CoV-2 and two of its variants. Journal of ethnopharmacology, 2021, Jun-28, Volume: 274 Topics: Animals; Antiviral Agents; Artemisia annua; Artemisinins; Cell Line; Cell Line, Tumor; Chlorocebus aethiops; COVID-19; COVID-19 Drug Treatment; Flavonoids; Humans; Plant Extracts; Plant Leaves; SARS-CoV-2; Spike Glycoprotein, Coronavirus; Vero Cells; Virus Replication	2021
Computational and experimental insights on the interaction of artemisinin, dihydroartemisinin and chloroquine with SARS-CoV-2 spike protein receptor-binding domain (RBD). Natural product research, 2022, Volume: 36, Issue:20 Topics: Angiotensin-Converting Enzyme 2; Antimalarials; Antiviral Agents; Artemisinins; Binding Sites; Chloroquine; COVID-19 Drug Treatment; Humans; Peptidyl-Dipeptidase A; SARS-CoV-2; Spike Glycoprotein, Coronavirus	2022
Ferroptosis plays an essential role in the antimalarial mechanism of low-dose dihydroartemisinin. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 148 Topics: Animals; Antimalarials; Artemisinins; Cell Death; Female; Ferroptosis; Humans; Malaria; Mice; Mice, Inbred C57BL; Parasites; Piperazines; Reactive Oxygen Species; Sorafenib	2022
A Plasmodium falciparum ubiquitin-specific protease (PfUSP) is essential for parasite survival and its disruption enhances artemisinin efficacy. The Biochemical journal, 2023, 01-13, Volume: 480, Issue:1 Topics: Animals; Antimalarials; Artemisinins; Drug Resistance; Humans; Malaria; Parasites; Plasmodium falciparum; Proteasome Endopeptidase Complex; Ubiquitin; Ubiquitin-Specific Proteases	2023
Exploring the Potential Mechanism of Artemisinin and Its Derivatives in the Treatment of Osteoporosis Based on Network Pharmacology and Molecular Docking. Computational and mathematical methods in medicine, 2022, Volume: 2022 Topics: Artemether; Artemisinins; Artesunate; Caspase 3; Drugs, Chinese Herbal; ErbB Receptors; Humans; Interleukin-17; Mitogen-Activated Protein Kinase 14; Molecular Docking Simulation; Network Pharmacology; Osteoporosis; Prolactin	2022
Evaluation of the Combined Effect of Artemisinin and Ferroptosis Inducer RSL3 against International journal of molecular sciences, 2022, Dec-23, Volume: 24, Issue:1 Topics: Animals; Artemisinins; Ferroptosis; Humans; Reactive Oxygen Species; Toxoplasma; Toxoplasmosis	2022
Assessment of artemisinin tolerance in Plasmodium falciparum clinical isolates in children with uncomplicated malaria in Ghana. Malaria journal, 2023, Feb-19, Volume: 22, Issue:1 Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Drug Combinations; Drug Tolerance; Ghana; Humans; Lumefantrine; Malaria; Malaria, Falciparum; Plasmodium falciparum	2023
Artemisinin derivatives induce oxidative stress leading to DNA damage and caspase-mediated apoptosis in Theileria annulata-transformed cells. Cell communication and signaling : CCS, 2023, 04-17, Volume: 21, Issue:1 Topics: Animals; Apoptosis; Artemisinins; Artesunate; Caspases; Cattle; DNA Damage; Oxidative Stress; Reactive Oxygen Species; Theileria annulata	2023
Ex vivo RSA and pfkelch13 targeted-amplicon deep sequencing reveal parasites susceptibility to artemisinin in Senegal, 2017. Malaria journal, 2023, May-26, Volume: 22, Issue:1 Topics: Animals; Antimalarials; Artemisinins; Drug Resistance; High-Throughput Nucleotide Sequencing; Humans; Malaria, Falciparum; Mutation; Parasites; Plasmodium falciparum; Protozoan Proteins; Senegal; Uganda	2023