Page last updated: 2024-08-25

artemotil and artemether

artemotil has been researched along with artemether in 40 studies

Research

Studies (40)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (2.50)	18.7374
1990's	11 (27.50)	18.2507
2000's	17 (42.50)	29.6817
2010's	8 (20.00)	24.3611
2020's	3 (7.50)	2.80

Authors

Authors	Studies
Brossi, A; Buchs, P; Dominguez Gerpe, L; Flippen-Anderson, JL; Luo, XD; Milhous, W; Peters, W; Venugopalan, B; Yeh, HJ	1
el-Feraly, FS; Kampinga, HH; Konings, AW; Malingré, TM; Moskal, TA; Pras, N; Woerdenbag, HJ	1
Ager, AL; Andersen, SL; Dong, Y; Edwards, G; Fu, H; Gerena, L; Holme, AD; Kyle, DE; McLean, WG; Milhous, WK; Miller, RE; Vennerstrom, JL; Walters, SM; Wesche, DL; Wood, JK	1
Bachi, MD; Hoos, R; Korshin, EE; Ploypradith, P; Posner, GH; Shapiro, TA; Szpilman, AM; Xie, S	1
ElSohly, MA; Galal, AM; Jacob, M; Ross, SA	1
Dembitsky, VM	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Emami, SA; Taleghani, A; Tayarani-Najaran, Z	1
Jiang, HJ; Li, Y; Mei, JY; Xiao, SH; Yin, JW; You, JQ	1
Jiang, HJ; Li, Y; Xiao, SH; Yang, YQ; Yin, JW	1
Hufford, CD; Lee, IS	1
Brewer, TG; Grate, SJ; Heiffer, MH; Levine, BS; Peggins, JO; Petras, JM; Schuster, BG; Weina, PJ	1
Brewer, TG; Grate, SJ; Heiffer, MH; Levine, BS; Peggins, JO; Petras, JM; Schuster, BG; Swearengen, J; Weina, PJ	1
Basco, LK; Le Bras, J	1
Ager, AL; Canfield, CJ; Heiffer, MH; Klayman, DL; Kyle, DE; Milhous, WK; Rossan, RN; Schuster, BG; Shmuklarsky, MJ; Tang, DB	1
Farina, C; Goglio, A; Olliaro, P	1
Brewer, TG; Fleckenstein, LL; Heiffer, MH; Li, QG; Masonic, K; Peggins, JO	1
McLean, WG; Ward, SA	1
Krudsood, S; Looareesuwan, S; Lugt, ChB; Oosterhuis, B; Peeters, PA; Peggins, JO; Schilizzi, BM; Sollie, FA; Wilairatana, P	1
Bauer, R; Efferth, T; Olbrich, A	1
Gettayacamin, M; Kyle, DE; Li, QG; Milhous, WK; Mog, SR; Si, YZ	1
Kager, PA	1
Bethell, D; Blakemore, WF; Cavanagh, JB; Day, NP; Dayan, A; Hien, TT; Mai, NT; Medana, I; Phu, NH; Turner, GD; Weller, RO; White, NJ	1
Majori, G	1
Chan, HW; Gerena, L; Haynes, RK; Ho, WY; Ko, CK; Kyle, DE; Peters, W; Robinson, BL	1
Medhi, B; Pandhi, P; Sukhija, M	2
Garner, P; Omari, A	1
Atemnkeng, MA; De Cock, K; Plaizier-Vercammen, J	1
Ashton, M; Asimus, SA; Elsherbiny, DA; Karlsson, MO; Simonsson, US	1
Clark, RL; Cox, EM; Gristwood, WE; Lerman, SA; White, TE	1
Efferth, T; Kaina, B	1
Hickman, M; Li, Q	1
Cao, XJ; Gong, XY	1
Chang, TK; Lau, AJ	1
Colak, M; Efferth, T; Elmasaoudi, K; Greten, HJ; Janah, R; Kadioglu, O; Ooko, E; Saeed, ME; Sarvi, S	1
Efferth, T; Greten, HJ; Kremsner, PG; Krishna, S; Saeed, MEM	1
Agarwal, P; Anvikar, AR; Pillai, CR; Srivastava, K	1
Barbieri, D; Blaud, M; Clain, J; Duval, R; Grougnet, R; Hammad, K; Houzé, S; Lavazec, C; Leproux, P; Maciuk, A; Michel, S; Neveu, G; Rondepierre, L; Sissoko, A; Vásquez-Ocmín, P	1
Chen, Y; Cheng, Y; Li, P; Liu, H; Lu, X; Ma, Y; Song, C; Wang, Y; Zhang, Z	1

Reviews

9 review(s) available for artemotil and artemether

Article	Year
Bioactive peroxides as potential therapeutic agents. European journal of medicinal chemistry, 2008, Volume: 43, Issue:2 Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Peroxides	2008
Artemisia: a promising plant for the treatment of cancer. Bioorganic & medicinal chemistry, 2020, 01-01, Volume: 28, Issue:1 Topics: Animals; Antineoplastic Agents, Phytogenic; Artemisia; Cell Proliferation; Humans; Molecular Structure; Neoplasms; Neoplasms, Experimental; Plant Extracts; Plants, Medicinal	2020
Metabolism of antimalarial sesquiterpene lactones. Pharmacology & therapeutics, 1990, Volume: 48, Issue:3 Topics: Animals; Antimalarials; Artemether; Artemisinins; Humans; Lactones; Sesquiterpenes; Structure-Activity Relationship	1990
[Three newly registered drugs in the Netherlands for the treatment and chemoprophylaxis of malaria: atovaquone-proguanil, artemether-lumefantrine and artemotil]. Nederlands tijdschrift voor geneeskunde, 2003, Feb-15, Volume: 147, Issue:7 Topics: Antimalarials; Artemether; Artemisinins; Atovaquone; Drug Approval; Drug Combinations; Drug Resistance; Ethanolamines; Fluorenes; Humans; Lumefantrine; Malaria; Naphthoquinones; Netherlands; Proguanil; Sesquiterpenes; Treatment Outcome	2003
[Combined antimalarial therapy using artemisinin]. Parassitologia, 2004, Volume: 46, Issue:1-2 Topics: Amodiaquine; Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Doxycycline; Drug Resistance; Drug Therapy, Combination; Humans; Malaria; Mefloquine; Plasmodium; Pyrimethamine; Quinine; Sesquiterpenes; Sulfadoxine	2004
Malaria: severe, life threatening. Clinical evidence, 2006, Issue:15 Topics: Acute Disease; Antimalarials; Artemether; Artemisinins; Artesunate; Humans; Malaria; Quinine; Sesquiterpenes	2006
Toxicity of the antimalarial artemisinin and its dervatives. Critical reviews in toxicology, 2010, Volume: 40, Issue:5 Topics: Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Clinical Trials as Topic; Developing Countries; Dogs; Drug Administration Routes; Drug-Related Side Effects and Adverse Reactions; Humans; Malaria; Rabbits; Rats; Sesquiterpenes	2010
Toxicokinetic and toxicodynamic (TK/TD) evaluation to determine and predict the neurotoxicity of artemisinins. Toxicology, 2011, Jan-11, Volume: 279, Issue:1-3 Topics: Animals; Antimalarials; Artemether; Artemisinins; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Neurotoxicity Syndromes; No-Observed-Adverse-Effect Level; Species Specificity	2011
Antischistosomal activity of artemisinin derivatives in vivo and in patients. Pharmacological research, 2016, Volume: 110 Topics: Animals; Artemether; Artemisinins; Artesunate; Female; Humans; Male; Parasite Egg Count; Schistosoma; Schistosomiasis; Schistosomicides; Treatment Outcome	2016

Trials

1 trial(s) available for artemotil and artemether

Article	Year
Dose-finding and efficacy study for i.m. artemotil (beta-arteether) and comparison with i.m. artemether in acute uncomplicated P. falciparum malaria. British journal of clinical pharmacology, 2002, Volume: 53, Issue:5 Topics: Acute Disease; Adolescent; Adult; Animals; Antimalarials; Artemether; Artemisinins; Dose-Response Relationship, Drug; Female; Humans; Injections, Intramuscular; Malaria, Falciparum; Male; Middle Aged; Sesquiterpenes	2002

Article

Year

Dose-finding and efficacy study for i.m. artemotil (beta-arteether) and comparison with i.m. artemether in acute uncomplicated P. falciparum malaria.

British journal of clinical pharmacology, 2002, Volume: 53, Issue:5

Topics: Acute Disease; Adolescent; Adult; Animals; Antimalarials; Artemether; Artemisinins; Dose-Response Relationship, Drug; Female; Humans; Injections, Intramuscular; Malaria, Falciparum; Male; Middle Aged; Sesquiterpenes

2002

Other Studies

30 other study(ies) available for artemotil and artemether

Article	Year
Arteether, a new antimalarial drug: synthesis and antimalarial properties. Journal of medicinal chemistry, 1988, Volume: 31, Issue:3 Topics: Animals; Antimalarials; Artemisinins; Magnetic Resonance Spectroscopy; Malaria; Mice; Models, Molecular; Plasmodium berghei; Plasmodium falciparum; Sesquiterpenes	1988
Cytotoxicity of artemisinin-related endoperoxides to Ehrlich ascites tumor cells. Journal of natural products, 1993, Volume: 56, Issue:6 Topics: Animals; Antineoplastic Agents, Phytogenic; Artemisinins; Carcinoma, Ehrlich Tumor; Cell Survival; Chemical Phenomena; Chemistry, Physical; Cisplatin; Doxorubicin; Peroxides; Sesquiterpenes; Structure-Activity Relationship; Tetrazolium Salts; Tumor Cells, Cultured	1993
Synthesis and antimalarial activity of sixteen dispiro-1,2,4, 5-tetraoxanes: alkyl-substituted 7,8,15,16-tetraoxadispiro[5.2.5. 2]hexadecanes. Journal of medicinal chemistry, 2000, Jul-13, Volume: 43, Issue:14 Topics: Alkanes; Animals; Antimalarials; Malaria; Mice; Neurites; Neuroblastoma; Plasmodium berghei; Plasmodium falciparum; Spiro Compounds; Structure-Activity Relationship; Tumor Cells, Cultured	2000
A short synthesis and biological evaluation of potent and nontoxic antimalarial bridged bicyclic beta-sulfonyl-endoperoxides. Journal of medicinal chemistry, 2003, Jun-05, Volume: 46, Issue:12 Topics: Animals; Antimalarials; Bridged Bicyclo Compounds, Heterocyclic; Malaria; Male; Mice; Mice, Inbred ICR; Plasmodium berghei; Plasmodium falciparum; Stereoisomerism; Structure-Activity Relationship; Sulfones	2003
Antifungal activity of artemisinin derivatives. Journal of natural products, 2005, Volume: 68, Issue:8 Topics: Antifungal Agents; Artemisinins; Candida albicans; Combinatorial Chemistry Techniques; Cryptococcus neoformans; Microbial Sensitivity Tests; Molecular Structure	2005
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
[Effect of arteether on Schistosoma japonicum]. Yao xue xue bao = Acta pharmaceutica Sinica, 1992, Volume: 27, Issue:3 Topics: Animals; Artemether; Artemisinins; Female; Histocytochemistry; Mice; Schistosoma japonicum; Schistosomiasis japonica; Schistosomicides; Sesquiterpenes; Therapeutic Equivalency	1992
[Comparative studies on histological and histochemical alterations of Schistosoma japonicum induced by arteether and artemether]. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1991, Volume: 12, Issue:5 Topics: Alkaline Phosphatase; Animals; Artemether; Artemisinins; Female; Glycogen; Histocytochemistry; Liver; Male; Mice; Schistosoma japonicum; Schistosomiasis japonica; Schistosomicides; Sesquiterpenes	1991
Fatal neurotoxicity of arteether and artemether. The American journal of tropical medicine and hygiene, 1994, Volume: 51, Issue:3 Topics: Animals; Antimalarials; Artemether; Artemisinins; Brain; Dogs; Dose-Response Relationship, Drug; Electrocardiography; Injections, Intramuscular; Male; Nervous System Diseases; Random Allocation; Rats; Rats, Sprague-Dawley; Reflex; Reproducibility of Results; Sesquiterpenes; Single-Blind Method; Spinal Cord	1994
Neurotoxicity in animals due to arteether and artemether. Transactions of the Royal Society of Tropical Medicine and Hygiene, 1994, Volume: 88 Suppl 1 Topics: Animals; Antimalarials; Antiprotozoal Agents; Artemether; Artemisinins; Brain Diseases; Central Nervous System Diseases; Dogs; Dose-Response Relationship, Drug; Gait; Heart Arrest; Rabbits; Rats; Respiratory Insufficiency; Sesquiterpenes	1994
In vitro activity of artemisinin derivatives against African isolates and clones of Plasmodium falciparum. The American journal of tropical medicine and hygiene, 1993, Volume: 49, Issue:3 Topics: Animals; Antimalarials; Artemether; Artemisinins; Chloroquine; Drug Resistance; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Sesquiterpenes	1993
Comparison of beta-artemether and beta-arteether against malaria parasites in vitro and in vivo. The American journal of tropical medicine and hygiene, 1993, Volume: 48, Issue:3 Topics: Animals; Antimalarials; Aotus trivirgatus; Artemether; Artemisinins; Chloroquine; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Malaria; Malaria, Falciparum; Male; Mefloquine; Mice; Plasmodium berghei; Plasmodium falciparum; Sesquiterpenes; Structure-Activity Relationship	1993
Failure to detect significant in-vitro activity of artemether and beta-arteether against bacteria and fungi by an agar dilution test. The Journal of antimicrobial chemotherapy, 1997, Volume: 40, Issue:5 Topics: Antifungal Agents; Artemether; Artemisinins; Bacteria; Fungi; Microbial Sensitivity Tests; Sesquiterpenes	1997
The pharmacokinetics and bioavailability of dihydroartemisinin, arteether, artemether, artesunic acid and artelinic acid in rats. The Journal of pharmacy and pharmacology, 1998, Volume: 50, Issue:2 Topics: Absorption; Animals; Antimalarials; Area Under Curve; Artemether; Artemisinins; Biological Availability; Bridged Bicyclo Compounds, Heterocyclic; Male; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Succinates	1998
In vitro neurotoxicity of artemisinin derivatives. Medecine tropicale : revue du Corps de sante colonial, 1998, Volume: 58, Issue:3 Suppl Topics: Animals; Antimalarials; Artemether; Artemisinins; Cell Differentiation; Central Nervous System Diseases; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Mice; Microscopy, Electron; Neuroblastoma; Neurons; Reproducibility of Results; Sesquiterpenes; Tumor Cells, Cultured	1998
mRNA expression profiles for the response of human tumor cell lines to the antimalarial drugs artesunate, arteether, and artemether. Biochemical pharmacology, 2002, Aug-15, Volume: 64, Issue:4 Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Cell Line; Gene Expression Profiling; Humans; Oligonucleotide Array Sequence Analysis; RNA, Messenger; Sesquiterpenes; Transcription, Genetic; Tumor Cells, Cultured	2002
Neurotoxicity and efficacy of arteether related to its exposure times and exposure levels in rodents. The American journal of tropical medicine and hygiene, 2002, Volume: 66, Issue:5 Topics: Animals; Anorexia; Antimalarials; Area Under Curve; Artemether; Artemisinins; Biological Availability; Malaria; Male; Mice; Muscle, Skeletal; Neurotoxins; Plasmodium berghei; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Tissue Distribution	2002
Neuropathological assessment of artemether-treated severe malaria. Lancet (London, England), 2003, Jul-26, Volume: 362, Issue:9380 Topics: Adult; Antimalarials; Artemether; Artemisinins; Brain Diseases; Brain Stem; Female; Humans; Malaria, Falciparum; Male; Quinine; Sesquiterpenes	2003
Convenient access both to highly antimalaria-active 10-arylaminoartemisinins, and to 10-alkyl ethers including artemether, arteether, and artelinate. Chembiochem : a European journal of chemical biology, 2005, Volume: 6, Issue:4 Topics: Animals; Antimalarials; Artemether; Artemisinins; Malaria; Mice; Molecular Structure; Parasitemia; Plasmodium berghei; Plasmodium falciparum; Plasmodium yoelii; Sesquiterpenes	2005
Effects of artemisinin, artemether, arteether on the pharmacokinetics of carbamazepine. Pharmacology, 2006, Volume: 76, Issue:3 Topics: Administration, Oral; Animals; Anticonvulsants; Antimalarials; Area Under Curve; Artemether; Artemisinins; Biological Availability; Carbamazepine; Chromatography, High Pressure Liquid; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Half-Life; Injections, Intramuscular; Lactones; Male; Rabbits; Sesquiterpenes; Suspensions	2006
Effects of artemisinin, artemether, and arteether on the pharmacokinetics of phenytoin. Methods and findings in experimental and clinical pharmacology, 2006, Volume: 28, Issue:2 Topics: Animals; Anticonvulsants; Antimalarials; Area Under Curve; Artemether; Artemisinins; Chromatography, High Pressure Liquid; Cross-Over Studies; Half-Life; Male; Metabolic Clearance Rate; Phenytoin; Rabbits; Sesquiterpenes	2006
Quality control of active ingredients in artemisinin-derivative antimalarials within Kenya and DR Congo. Tropical medicine & international health : TM & IH, 2007, Volume: 12, Issue:1 Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Capsules; Chromatography, High Pressure Liquid; Democratic Republic of the Congo; Dosage Forms; Endemic Diseases; Humans; Kenya; Malaria, Falciparum; Quality Control; Sesquiterpenes; Tablets	2007
A model based assessment of the CYP2B6 and CYP2C19 inductive properties by artemisinin antimalarials: implications for combination regimens. Journal of pharmacokinetics and pharmacodynamics, 2008, Volume: 35, Issue:2 Topics: Adult; Anticonvulsants; Antimalarials; Artemether; Artemisinins; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2C19; Drug Combinations; Enzyme Induction; Female; Genotype; Humans; Male; Mephenytoin; Models, Statistical; Oxidoreductases, N-Demethylating; Phenotype	2008
Developmental toxicity of artesunate in the rat: comparison to other artemisinins, comparison of embryotoxicity and kinetics by oral and intravenous routes, and relationship to maternal reticulocyte count. Birth defects research. Part B, Developmental and reproductive toxicology, 2008, Volume: 83, Issue:4 Topics: Administration, Oral; Animals; Artemether; Artemisinins; Artesunate; Cesarean Section; Drug Administration Routes; Embryo Loss; Embryo, Mammalian; Female; Fetus; Injections, Intravenous; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Reticulocyte Count; Reticulocytes	2008
Preparation of molecularly imprinted polymers for artemisinin based on the surfaces of silica gel. Journal of biotechnology, 2011, Apr-20, Volume: 153, Issue:1-2 Topics: Adsorption; Artemether; Artemisinins; Hydrogen Bonding; Kinetics; Microscopy, Electron, Scanning; Molecular Imprinting; Polymers; Porosity; Silica Gel; Spectroscopy, Fourier Transform Infrared; Surface Properties; Temperature	2011
Fetal bovine serum and human constitutive androstane receptor: evidence for activation of the SV23 splice variant by artemisinin, artemether, and arteether in a serum-free cell culture system. Toxicology and applied pharmacology, 2014, Jun-01, Volume: 277, Issue:2 Topics: Artemether; Artemisinins; Biological Assay; Cell Culture Techniques; Cell Survival; Dose-Response Relationship, Drug; Genes, Reporter; Hep G2 Cells; Humans; Ligands; Protein Isoforms; Receptors, Androgen; Reproducibility of Results; Serum; Time Factors; Transfection	2014
Artemisinin derivatives induce iron-dependent cell death (ferroptosis) in tumor cells. Phytomedicine : international journal of phytotherapy and phytopharmacology, 2015, Oct-15, Volume: 22, Issue:11 Topics: Apoptosis; Artemether; Artemisinins; Artesunate; Cell Death; Cell Line, Tumor; Cyclohexylamines; Deferoxamine; Gene Expression Regulation, Neoplastic; Humans; Inhibitory Concentration 50; Iron; Molecular Structure; Oligonucleotide Array Sequence Analysis; Phenylenediamines	2015
The Indian journal of medical research, 2017, Volume: 146, Issue:5 Topics: Anti-Bacterial Agents; Antimalarials; Artemether; Artemisinins; Atovaquone; Azithromycin; Chloroquine; Doxycycline; Ethanolamines; Fluorenes; Humans; India; Lumefantrine; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Quinine; Quinolines	2017
A Chemically Stable Fluorescent Mimic of Dihydroartemisinin, Artemether, and Arteether with Conserved Bioactivity and Specificity Shows High Pharmacological Relevance to the Antimalarial Drugs. ACS infectious diseases, 2020, 07-10, Volume: 6, Issue:7 Topics: Antimalarials; Artemether; Artemisinins	2020
Exploring the Potential Mechanism of Artemisinin and Its Derivatives in the Treatment of Osteoporosis Based on Network Pharmacology and Molecular Docking. Computational and mathematical methods in medicine, 2022, Volume: 2022 Topics: Artemether; Artemisinins; Artesunate; Caspase 3; Drugs, Chinese Herbal; ErbB Receptors; Humans; Interleukin-17; Mitogen-Activated Protein Kinase 14; Molecular Docking Simulation; Network Pharmacology; Osteoporosis; Prolactin	2022