artemether has been researched along with artemisinin in 107 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (14.02) | 18.7374 |
| 1990's | 16 (14.95) | 18.2507 |
| 2000's | 21 (19.63) | 29.6817 |
| 2010's | 37 (34.58) | 24.3611 |
| 2020's | 18 (16.82) | 2.80 |
| Authors | Studies |
|---|---|
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Balogh, I; Kim, HY; Koczok, K; Korade, Z; Liu, W; Mirnics, K; Porter, NA; Tallman, KA; Xu, L | 1 |
| Dong, G; Liu, N; Sheng, C; Wang, Y; Wu, S | 1 |
| Emami, SA; Taleghani, A; Tayarani-Najaran, Z | 1 |
| Cheong, I; Li, J; Liu, NN; Wang, H; Zhou, J | 1 |
| Lalloo, D; Trevett, A | 1 |
| Than, M; Thwe, Y; Win, K | 1 |
| Hufford, CD; Lee, IS | 1 |
| Song, ZY; Zhao, KC | 1 |
| Wang, TY | 1 |
| Gu, HM; Peters, W; Warhurst, DC | 2 |
| Chen, L; Gu, HM; Li, GD; Li, J; Qian, YL; Waki, S; Zhu, MY | 1 |
| Du, YL; Jiang, Q; Li, CS | 1 |
| Li, ZL; Peters, W; Robinson, BL; Warhurst, DC | 1 |
| Chen, QM; Song, ZY; Zhao, KC | 1 |
| Beale, GH; Thaithong, S | 1 |
| Gu, HM; Li, ZL; Peters, W; Warhurst, DC | 1 |
| Guo, XB; Jian, HX; Jin, R; Li, GQ; Li, ZY; Wang, ZC | 1 |
| Ager, AL; Klayman, DL; Lin, AJ | 1 |
| Hien, TT | 1 |
| Looareesuwan, S | 1 |
| Basco, LK; Le Bras, J | 1 |
| Liew, FY; Yang, DM | 1 |
| Ambroise-Thomas, P | 1 |
| Davis, TM; Johnston, WA; Manning, LS; Skinner, TS | 1 |
| Berens, RL; Curiel, TJ; Krug, EC; Nash, PB | 1 |
| Li, Y; Wu, YL | 1 |
| McLean, WG; Ward, SA | 1 |
| Boele van Hensbroek, M | 1 |
| Nosten, F; van Vugt, M; White, NJ | 1 |
| Dodd, CC; Edwards, G; McLean, WG; Park, BK; Sadler, CJ; Smith, SL; Ward, SA | 1 |
| Tu, Y | 1 |
| Chen, M; Keiser, J; Tanner, M; Utzinger, J; Xiao, S; Zheng, J | 1 |
| Marsh, K | 1 |
| Chen, XY; Duan, X; Liu, GJ; Ni, J; Qiao, JQ; Wang, Q; Wei, JF; Wu, TX; Zhang, MM; Zheng, J; Zhou, LK | 1 |
| Majori, G | 1 |
| Garner, P; Omari, A | 1 |
| Medhi, B; Pandhi, P; Sukhija, M | 1 |
| Hi, YC; Huang, F; Tang, LH; Wang, QM | 1 |
| Ahmed, ES; Elamin, SB; Elhassan, AH; Elmardi, KA; Malik, EM; Mannan, AA; Mohamed, TA; Mowien, RM | 1 |
| Chekem, L; Wierucki, S | 1 |
| Davis, TM; Ilett, KF; Karunajeewa, HA; Manning, L; Mueller, I | 1 |
| Galasso, V; Modelli, A | 1 |
| Amewu, R; Ellis, GL; Hall, C; O'Neill, PM; Rimmer, K; Ward, SA | 1 |
| Goodman, CA; Snow, RW; Wasunna, B; Zurovac, D | 1 |
| Ajanga, A; Amin, AA; Gitonga, CW; Kangwana, BB; Noor, AM; Snow, RW | 1 |
| Ashton, M; Asimus, SA; Elsherbiny, DA; Karlsson, MO; Simonsson, US | 1 |
| Ashley, EA; Balkan, S; Bukirwa, H; Checchi, F; Dorsey, G; Guthmann, JP; Olliaro, P; Pinoges, L; Taylor, WR; Turyakira, E; Urruta, PP; van den Broek, I; van Herp, M; Zongo, I | 1 |
| Clark, RL; Cox, EM; Gristwood, WE; Lerman, SA; White, TE | 1 |
| Hou, J; Wang, D; Wang, H; Zhang, R | 1 |
| Campagna, AM; Patnaik, MM | 1 |
| Oguonu, T; Okafor, HU; Shu, EN | 1 |
| Efferth, T; Kaina, B | 1 |
| Bonato, PS; Collins, CH; Faria, AM; Jabor, VA; Jardim, IC; Magalhães, IR | 1 |
| Carvalho, LJ; Clemmer, L; Frangos, JA; Martins, YC; Zanini, GM | 1 |
| Jessing, KK; Juhler, RK; Strobel, BW | 1 |
| Du, F; Liu, T; Xing, J; Zhu, F | 1 |
| Kusriastuti, R; Surya, A | 1 |
| Balbiano, R; Calleri, G; Caramello, P | 1 |
| George, LB; Jasrai, YT; Kumar, SP; Pandya, HA; Patel, SK | 1 |
| Ashton, M; Ericsson, T; Hoffmann, KJ; Sundell, J; Torkelsson, A | 1 |
| Enweji, N; Gheysari, F; Kaddumukasa, M; Kamugisha, E; Kironde, F; Sendagire, H; Swedberg, G | 1 |
| Conyers, RC; Mazzone, JR; Mott, BT; Posner, GH; Siegler, MA; Sullivan, DJ; Tripathi, AK | 1 |
| Carruthers, VB; Hencken, CP; Jones-Brando, L; Posner, GH; Schultz, TL; Woodard, LE; Yolken, RH | 1 |
| Li, GX; Wang, W; Wang, YH; Xu, FL; Zhang, XG; Zhao, SS | 1 |
| Chang, TK; Lau, AJ | 1 |
| Bala, N; Betuela, I; Davis, TM; Hetzel, MW; Lavu, EK; Page-Sharp, M; Pulford, J | 1 |
| Batty, KT; Senarathna, SM | 1 |
| Corsello, MA; Garg, NK | 1 |
| Hikasa, Y; Iguchi, A; Matsuu, A; Matsuyama, K | 1 |
| Benjamin, JM; Betuela, I; Bona, C; Davis, TM; Davis, WA; Karl, S; Kasian, B; Kattenberg, JH; Koleala, T; Laman, M; Lorry, L; Manning, L; Moore, BR; Mueller, I; Robinson, LJ; Rosanas-Urgell, A; Sambale, N; Siba, PM; Warrel, J; Yadi, G | 1 |
| Benjamin, J; Davis, TM; Ibam, C; Karl, S; Kasian, B; Koleala, T; Laman, M; Moore, BR; Mueller, I; Siba, PM; St Pierre, TG; Waltmann, A; Woodward, RC | 1 |
| Bassat, Q; Djimde, A; Hamed, K; Ogutu, B; Stricker, K | 1 |
| Djimde, AA; Hamed, K; Kuhen, K; Makanga, M | 1 |
| Bonfill, M; Cusido, RM; Dilshad, E; Mirza, B; Ramirez Estrada, K | 1 |
| Acheampong, PR; Antwi, GD; Bart Plange, C; Cairns, M; Chandramohan, D; Tagbor, H | 1 |
| Batra, S; Biswas, S; Chauhan, BS; Gunjan, S; Pandey, SK; Singh, S; Singh, SK; Srivastava, K; Tripathi, R | 1 |
| Ackermann, I; Aubin, F; Carn, G; Gesase, S; Lusingu, JPA; Mnkande, E; Mrango, Z; Mtoro, A; Ngocho, JS; Ogutu, B; Onyango, KO; Ouedraogo, A; Sirima, SB; Strub, N; Vanraes, J; Yaro, JB | 1 |
| Iyengar, K; Roepe, PD; Siriwardana, A | 1 |
| Chorlton, SD | 1 |
| Nosten, F | 1 |
| César, IC; Fernandes, C; Pianetti, GA; Ricoy, LBM; Rivelli, GG | 1 |
| Efferth, T; Naß, J | 1 |
| Dai, R; Dai, T; Guo, Z; Jiang, W; Xie, Y | 1 |
| Beavogui, AH; Borghini-Fuhrer, I; Djimdé, AA; Duparc, S; Felices, M; Funck-Brentano, C; Khan, Y; Ouedraogo, JB; Ouologuem, N; Sagara, I; Sirima, SB; Soulama, I; Voiriot, P | 1 |
| Aweeka, F; Huang, L; Hughes, E; Kajubi, R; Mwebaza, N; Mwima, MW; Nguyen, V; Nyunt, MM; Orukan, F; Parikh, S | 1 |
| Gille, L; Machín, L; Monzote, L; Nápoles, R | 1 |
| Jiang, Z; Qiao, S; Sun, F; Zhang, H | 1 |
| Abdallah, KS; Bacar, A; Deng, C; Li, G; Li, M; Liu, R; Lu, C; Silai, R; Song, J; Tan, R; Wu, W; Xu, Q; Yuan, Y; Zhang, H; Zheng, S | 1 |
| Aweeka, F; Ehrlich, H; Freeman, T; French, J; Goodwin, J; Huang, L; Kajubi, R; Kay, K; Li, F; Mwebaza, N; Ou, J; Parikh, S; Riggs, M; Ruiz-Garcia, A; Wade, M; Wang, K | 1 |
| Augusto, O; Byamugisha, J; Clerk, C; Dellicour, S; Desai, M; Gomes, M; Guérin, PJ; Hill, J; Kagawa, M; Kariuki, S; Kisinza, W; Manyando, C; McGready, R; Mehta, U; Mosha, D; Mrema, S; Njunju, EM; Nosten, F; Rouamba, T; Rulisa, S; Saito, M; Sevene, E; Singlovic, J; Stepniewska, K; Stergachis, A; Ter Kuile, FO; Tinto, H; Vala, A; van Eijk, AM; Were, E; Yore, M | 1 |
| Chen, Y; Cheng, Y; Li, P; Liu, H; Lu, X; Ma, Y; Song, C; Wang, Y; Zhang, Z | 1 |
| Adjei, GO; Ahorhorlu, SY; Alifrangis, M; Duah-Quashie, NO; Dzudzor, B; Hansson, H; Jensen, RW; Kudzi, W; Nartey, ET; Quashie, NB; Wang, CW; Zoiku, F | 1 |
| Abala, C; Nyeko, R; Obiya, EM; Otim, F | 1 |
| Akala, HM; Amwoma, JG; Andagalu, BM; Chemwor, GC; Cheruiyot, AC; Egbo, TE; Garges, EC; Juma, DW; Juma, JA; Kamau, E; Mwakio, EW; Ogutu, BR; Okoth, RO; Onyango, IA; Opot, BH; Roth, AL; Wakoli, DM; Watson, OJ; Yedah, RA | 1 |
| Gao, HM; Gao, XN; Kang, JJ; Ma, Y; Sun, P; Yang, L; Zhang, D; Zhao, YF | 1 |
| Aguas, R; Amaratunga, C; Boni, MF; Dhorda, M; Dondorp, AM; Gao, B; Nguyen, TD; Tran, TN; White, NJ | 1 |
| Abdelkader, O; Boulotigam, K; Djimadoum, M; Djimrassengar, H; Doderer-Lang, C; Hassoumi, M; Issa, AH; Issa, MS; Mahamat, MHT; Menard, D; Ndihiokubwayo, JB; Rasmussen, C; Saleh, IDM; Warsame, M | 1 |
| Dellicour, S; Gutman, JR; Hill, J; Ochodo, E; Osoro, CB; Ter Kuile, F; Young, T | 1 |
| D'Alessandro, U; Dabira, ED; Diakite, H; Djimde, M; Dorlo, TP; Erhart, A; González, R; Kabore, B; Kayentao, K; Keita, M; Macuacua, S; Menendez, C; Mens, P; Muhindo, HM; Piqueras, M; Sagara, I; Schallig, H; Sevene, E; Tinto, H; Traore, M; Tshiongo, JK; Vala, A | 1 |
| Acharya, S; Arnold, L; Chico, RM; Gore-Langton, GR; Lufele, E; Moore, BR; Price, RN; Rogerson, SJ; Ter Kuile, FO; Thriemer, K; Unger, HW; van Eijk, AM; Wu, C | 1 |
27 review(s) available for artemether and artemisinin
| Article | Year |
|---|---|
Tackling Fungal Resistance by Biofilm Inhibitors.
Topics: Animals; Antifungal Agents; Biofilms; Drug Discovery; Drug Resistance, Fungal; Fungi; Humans; Models, Molecular; Mycoses; Small Molecule Libraries | 2017 |
Artemisia: a promising plant for the treatment of cancer.
Topics: Animals; Antineoplastic Agents, Phytogenic; Artemisia; Cell Proliferation; Humans; Molecular Structure; Neoplasms; Neoplasms, Experimental; Plant Extracts; Plants, Medicinal | 2020 |
A new look at an old drug: artemesinin and qinghaosu.
Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Humans; Malaria, Cerebral; Malaria, Falciparum; Sesquiterpenes | 1992 |
Metabolism of antimalarial sesquiterpene lactones.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Humans; Lactones; Sesquiterpenes; Structure-Activity Relationship | 1990 |
Studies of qinghaosu and its active derivatives in biological materials and their pharmacokinetics.
Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Sesquiterpenes; Structure-Activity Relationship | 1989 |
An overview of the clinical use of artemisinin and its derivatives in the treatment of falciparum malaria in Viet Nam.
Topics: Adolescent; Adult; Antimalarials; Antiprotozoal Agents; Artemether; Artemisinins; Artesunate; Clinical Trials as Topic; Double-Blind Method; Drug Resistance; Humans; Malaria, Falciparum; Middle Aged; Sesquiterpenes; Vietnam | 1994 |
Overview of clinical studies on artemisinin derivatives in Thailand.
Topics: Antimalarials; Antiprotozoal Agents; Artemether; Artemisinins; Artesunate; Clinical Trials as Topic; Drug Resistance; Humans; Malaria, Falciparum; Sesquiterpenes; Thailand | 1994 |
[The role of qinghaosu derivatives in the treatment of malaria in 1995].
Topics: Antimalarials; Artemether; Artemisinins; Clinical Trials as Topic; Drug Resistance; Forecasting; Humans; Malaria, Falciparum; Sesquiterpenes; Treatment Outcome | 1995 |
How Chinese scientists discovered qinghaosu (artemisinin) and developed its derivatives? What are the future perspectives?
Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Drug Evaluation; Drug Resistance; Forecasting; Humans; Malaria, Falciparum; Medicine, Chinese Traditional; Sesquiterpenes | 1998 |
The role of the qinghaosu derivatives in the treatment of severe malaria.
Topics: Adult; Antimalarials; Artemether; Artemisinins; Child; Humans; Malaria; Quinine; Research Design; Sesquiterpenes | 1998 |
Intrarectal artemisinin derivatives.
Topics: Absorption; Administration, Rectal; Adult; Antimalarials; Artemether; Artemisinins; Artesunate; Child; Humans; Malaria; Metabolic Clearance Rate; Sesquiterpenes; Suppositories | 1998 |
Current progress in the development and use of artemether for chemoprophylaxis of major human schistosome parasites.
Topics: Animals; Artemether; Artemisinins; Humans; Schistosoma; Schistosomiasis; Schistosomicides; Sesquiterpenes | 2001 |
Artemesinins for severe malaria in Africa?
Topics: Adult; Antimalarials; Artemether; Artemisia; Artemisinins; Child; Drug Evaluation; Humans; Malaria; Phytotherapy; Sesquiterpenes | 2002 |
[Systematic review of benefits and harms of artemisinin-type compounds for preventing schistosomiasis].
Topics: Adult; Artemether; Artemisinins; Artesunate; Double-Blind Method; Female; Humans; Male; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Schistosomiasis japonica; Schistosomicides; Sesquiterpenes | 2003 |
[Combined antimalarial therapy using artemisinin].
Topics: Amodiaquine; Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Doxycycline; Drug Resistance; Drug Therapy, Combination; Humans; Malaria; Mefloquine; Plasmodium; Pyrimethamine; Quinine; Sesquiterpenes; Sulfadoxine | 2004 |
Malaria in endemic areas.
Topics: Antimalarials; Artemether; Artemisinins; Blood Transfusion; Chloroquine; Deferoxamine; Drug Combinations; Humans; Malaria; Malaria, Falciparum; Pyrimethamine; Quinine; Sesquiterpenes; Sulfadoxine | 2003 |
Rectal administration of artemisinin derivatives for the treatment of malaria.
Topics: Administration, Rectal; Area Under Curve; Artemether; Artemisinins; Artesunate; Humans; Malaria; Sesquiterpenes | 2007 |
Toxicity of the antimalarial artemisinin and its dervatives.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Clinical Trials as Topic; Developing Countries; Dogs; Drug Administration Routes; Drug-Related Side Effects and Adverse Reactions; Humans; Malaria; Rabbits; Rats; Sesquiterpenes | 2010 |
A review of dihydroartemisinin as another gift from traditional Chinese medicine not only for malaria control but also for schistosomiasis control.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Drugs, Chinese Herbal; Female; Malaria, Falciparum; Mice; Praziquantel; Schistosomiasis japonica; Schistosomicides | 2014 |
Synthetic chemistry fuels interdisciplinary approaches to the production of artemisinin.
Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Drug Resistance, Microbial; Malaria; Molecular Structure; Plasmodium falciparum | 2015 |
Tailoring a Pediatric Formulation of Artemether-Lumefantrine for Treatment of Plasmodium falciparum Malaria.
Topics: Antimalarials; Artemether; Artemisinins; Chemistry, Pharmaceutical; Clinical Trials, Phase III as Topic; Drug Combinations; Ethanolamines; Fluorenes; Humans; Lumefantrine; Malaria, Falciparum; Plasmodium falciparum; Randomized Controlled Trials as Topic; Tablets | 2015 |
The emerging threat of artemisinin resistance in malaria: focus on artemether-lumefantrine.
Topics: Africa South of the Sahara; Antimalarials; Artemether; Artemisinins; Asia; Drug Combinations; Drug Resistance; Ethanolamines; Fluorenes; Humans; Lumefantrine; Malaria, Falciparum; Plasmodium falciparum | 2015 |
Toxoplasma gondii and schizophrenia: a review of published RCTs.
Topics: Antiparasitic Agents; Artemether; Artemisinins; Brain; Genotype; Humans; Randomized Controlled Trials as Topic; Schizophrenia; Toxoplasma; Toxoplasmosis; Trimethoprim | 2017 |
The activity of Artemisia spp. and their constituents against Trypanosomiasis.
Topics: Antimalarials; Artemether; Artemisia; Artemisinins; Artesunate; Oils, Volatile; Phytochemicals; Plant Extracts; Scopoletin; Trypanosomiasis | 2018 |
Pregnancy outcomes after first-trimester treatment with artemisinin derivatives versus non-artemisinin antimalarials: a systematic review and individual patient data meta-analysis.
Topics: Abortion, Spontaneous; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Drug Combinations; Ethanolamines; Female; Humans; Malaria; Malaria, Falciparum; Pregnancy; Pregnancy Outcome; Pregnancy Trimester, First; Prospective Studies; Quinine; Stillbirth | 2023 |
[Microbial transformation of artemisinin and its derivatives].
Topics: Animals; Antimalarials; Antiviral Agents; Artemether; Artemisinins; Mammals | 2023 |
The effect and control of malaria in pregnancy and lactating women in the Asia-Pacific region.
Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Asia; Female; Humans; Lactation; Malaria; Malaria, Falciparum; Pregnancy | 2023 |
12 trial(s) available for artemether and artemisinin
| Article | Year |
|---|---|
Comparison of combinations of parenteral artemisinin derivatives plus oral mefloquine with intravenous quinine plus oral tetracycline for treating cerebral malaria.
Topics: Adolescent; Adult; Antimalarials; Artemether; Artemisinins; Artesunate; Humans; Malaria, Cerebral; Mefloquine; Middle Aged; Prospective Studies; Quinine; Sesquiterpenes; Tetracycline | 1992 |
Antimalarial efficacy and mode of action of qinghaosu and its derivatives in experimental models. China Cooperative Research Group on qinghaosu and its derivatives as antimalarials.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Erythrocytes; Malaria; Mice; Multicenter Studies as Topic; Plasmodium; Sesquiterpenes | 1982 |
Metabolism and pharmacokinetics of qinghaosu and its derivatives. China Cooperative Research Group on qinghaosu and its derivatives as antimalarials.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Biological Availability; Biotransformation; Multicenter Studies as Topic; Rabbits; Rats; Sesquiterpenes; Tissue Distribution | 1982 |
Studies on the toxicity of qinghaosu and its derivatives. China Cooperative Research Group on qinghaosu and its derivatives as antimalarials.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Dogs; Female; Guinea Pigs; Macaca mulatta; Male; Mice; Multicenter Studies as Topic; Mutagenicity Tests; Rabbits; Rats; Rats, Inbred Strains; Sesquiterpenes | 1982 |
Clinical studies on the treatment of malaria with qinghaosu and its derivatives. China Cooperative Research Group on qinghaosu and its derivatives as antimalarials.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Humans; Malaria; Multicenter Studies as Topic; Plasmodium falciparum; Plasmodium vivax; Sesquiterpenes | 1982 |
Therapeutic efficacy and effect on gametocyte carriage of an artemisinin and a non-based combination treatment in children with uncomplicated P. falciparum malaria, living in an area with high-level chloroquine resistance.
Topics: Amodiaquine; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Follow-Up Studies; Gametogenesis; Humans; Infant; Lumefantrine; Malaria, Falciparum; Male; Nigeria; Plasmodium falciparum; Polymerase Chain Reaction; Pyrimethamine; Sulfalene; Treatment Outcome | 2010 |
Artemisinin-naphthoquine versus artemether-lumefantrine for uncomplicated malaria in Papua New Guinean children: an open-label randomized trial.
Topics: Adult; Antimalarials; Artemether; Artemisinins; Ethanolamines; Female; Fluorenes; Humans; Lumefantrine; Malaria, Falciparum; Male; Middle Aged | 2014 |
Seasonal malaria chemoprevention in an area of extended seasonal transmission in Ashanti, Ghana: an individually randomised clinical trial.
Topics: Amodiaquine; Antimalarials; Artemether; Artemisinins; Chemoprevention; Child, Preschool; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Ghana; Humans; Infant; Infant, Newborn; Lumefantrine; Malaria; Male; Pyrimethamine; Quinolines; Rain; Seasons; Sulfadoxine | 2016 |
Comparison of artesunate-mefloquine and artemether-lumefantrine fixed-dose combinations for treatment of uncomplicated Plasmodium falciparum malaria in children younger than 5 years in sub-Saharan Africa: a randomised, multicentre, phase 4 trial.
Topics: Africa South of the Sahara; Antimalarials; Artemether; Artemisinins; Artesunate; Child, Preschool; Ethanolamines; Female; Fluorenes; Humans; Infant; Lumefantrine; Malaria, Falciparum; Male; Mefloquine; Patient Safety; Polymerase Chain Reaction | 2016 |
Artemisinin-piperaquine versus artemether-lumefantrine for treatment of uncomplicated Plasmodium falciparum malaria in Grande Comore island: an open-label, non-randomised controlled trial.
Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Drug Combinations; Ethanolamines; Fluorenes; Humans; Malaria; Malaria, Falciparum; Piperazines; Plasmodium falciparum; Quinolines | 2022 |
Therapeutic response to artemisinin combination therapies among individuals with Plasmodium falciparum single infection vs mixed Plasmodium species infections: a retrospective posthoc analysis in Kisumu County, western Kenya.
Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Drug Combinations; Humans; Kenya; Malaria; Malaria, Falciparum; Plasmodium falciparum; Quinolines; Reinfection; Retrospective Studies | 2023 |
Efficacy and safety of pyronaridine-artesunate (PYRAMAX) for the treatment of
Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Clinical Trials, Phase III as Topic; Drug Combinations; Female; Humans; Infant; Malaria; Malaria, Falciparum; Pregnancy; Pregnant Women; Randomized Controlled Trials as Topic; Sub-Saharan African People; Treatment Outcome | 2023 |
68 other study(ies) available for artemether and artemisinin
| Article | Year |
|---|---|
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
The Effect of Small Molecules on Sterol Homeostasis: Measuring 7-Dehydrocholesterol in Dhcr7-Deficient Neuro2a Cells and Human Fibroblasts.
Topics: Animals; Cell Line; Dehydrocholesterols; Dose-Response Relationship, Drug; Fibroblasts; Homeostasis; Humans; Mice; Molecular Conformation; Neurons; Oxidoreductases Acting on CH-CH Group Donors; Small Molecule Libraries; Sterols; Structure-Activity Relationship | 2016 |
Evaluation of artemisinin derivative artemether as a fluconazole potentiator through inhibition of Pdr5.
Topics: Antifungal Agents; Artemisinins; ATP-Binding Cassette Transporters; Candida; Cryptococcus neoformans; Dose-Response Relationship, Drug; Fluconazole; Microbial Sensitivity Tests; Molecular Structure; Saccharomyces cerevisiae; Structure-Activity Relationship | 2021 |
Follow-up observation on the therapeutic effects and remote reactions of artemisinin (Qinghaosu) and artemether in treating malaria in pregnant woman.
Topics: Antimalarials; Artemether; Artemisinins; Female; Follow-Up Studies; Humans; Malaria; Pregnancy; Pregnancy Complications, Infectious; Sesquiterpenes | 1989 |
Hemolysis induced by artemisinin and its derivatives in vitro.
Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Erythrocytes; Hemoglobins; Hemolysis; Humans; Pyrans; Sesquiterpenes | 1986 |
Fluorometric determination of the antimalarial efficacy of artemisinin and artemether against Plasmodium falciparum in vitro.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Chloroquine; Plasmodium falciparum; Sesquiterpenes; Spectrometry, Fluorescence | 1988 |
[Development of a qinghaosu-resistant line of Plasmodium berghei ANKA and N strain].
Topics: Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Drug Resistance, Microbial; Malaria; Male; Mice; Plasmodium berghei; Primaquine; Pyrans; Sesquiterpenes | 1986 |
The chemotherapy of rodent malaria, XL. The action of artemisinin and related sesquiterpenes.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Drug Resistance; Malaria; Male; Mice; Pigments, Biological; Plasmodium berghei; Pyrans; Sesquiterpenes | 1986 |
[Studies on the pharmacokinetics of qinghaosu and two of its active derivatives in dogs].
Topics: Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Dogs; Kinetics; Male; Pyrans; Sesquiterpenes | 1986 |
Susceptibility of Thai isolates of Plasmodium falciparum to artemisinine (qinghaosu) and artemether.
Topics: Animals; Artemether; Artemisinins; Chloroquine; Drug Combinations; Microbial Sensitivity Tests; Plasmodium falciparum; Pyrans; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Thailand | 1985 |
Rapid action of Qinghaosu and related drugs on incorporation of [3H]isoleucine by Plasmodium falciparum in vitro.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Isoleucine; Kinetics; Plasmodium falciparum; Protein Biosynthesis; Pyrans; Sesquiterpenes; Tritium | 1983 |
Effects of qinghaosu and related compounds on incorporation of [G-3H] hypoxanthine by Plasmodium falciparum in vitro.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Hypoxanthine; Hypoxanthines; Plasmodium falciparum; Pyrans; Sesquiterpenes; Time Factors | 1983 |
Clinical studies on treatment of cerebral malaria with qinghaosu and its derivatives.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Brain Diseases; Child; Child, Preschool; Female; Humans; Malaria; Male; Middle Aged; Plasmodium falciparum; Sesquiterpenes | 1982 |
Antimalarial activity of dihydroartemisinin derivatives by transdermal application.
Topics: Administration, Cutaneous; Animals; Antimalarials; Artemether; Artemisinins; Gels; Malaria; Mice; Plasmodium berghei; Sesquiterpenes; Structure-Activity Relationship | 1994 |
In vitro activity of artemisinin derivatives against African isolates and clones of Plasmodium falciparum.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Chloroquine; Drug Resistance; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Sesquiterpenes | 1993 |
Effects of qinghaosu (artemisinin) and its derivatives on experimental cutaneous leishmaniasis.
Topics: Animals; Artemether; Artemisinins; Artesunate; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Leishmania; Leishmaniasis, Cutaneous; Mice; Mice, Inbred BALB C; Mice, Inbred CBA; Sesquiterpenes; Time Factors | 1993 |
In vitro stage-specific sensitivity of Plasmodium falciparum to quinine and artemisinin drugs.
Topics: Adult; Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Drug Evaluation, Preclinical; Drug Resistance; Humans; In Vitro Techniques; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Quinine; Sesquiterpenes | 1996 |
Selection and characterization of Toxoplasma gondii mutants resistant to artemisinin.
Topics: Animals; Antimalarials; Antiprotozoal Agents; Artemether; Artemisinins; Drug Resistance; Ethyl Methanesulfonate; Female; Humans; Methylnitronitrosoguanidine; Mice; Mice, Inbred ICR; Mutagenesis; Sesquiterpenes; Toxoplasma; Toxoplasmosis, Animal | 1998 |
In vitro neurotoxicity of artemisinin derivatives.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Cell Differentiation; Central Nervous System Diseases; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Mice; Microscopy, Electron; Neuroblastoma; Neurons; Reproducibility of Results; Sesquiterpenes; Tumor Cells, Cultured | 1998 |
The role of glutathione in the neurotoxicity of artemisinin derivatives in vitro.
Topics: Animals; Antimalarials; Antimetabolites; Antioxidants; Artemether; Artemisinins; Buthionine Sulfoximine; Drug Interactions; Glutathione; Hemin; Humans; Mice; Neurites; Sesquiterpenes; Tumor Cells, Cultured | 2001 |
The development of new antimalarial drugs: qinghaosu and dihydro-qinghaosu.
Topics: Animals; Antimalarials; Artemether; Artemisia; Artemisinins; Artesunate; Drugs, Chinese Herbal; Humans; Sesquiterpenes | 1999 |
Effects of artemisinin, artemether, and arteether on the pharmacokinetics of phenytoin.
Topics: Animals; Anticonvulsants; Antimalarials; Area Under Curve; Artemether; Artemisinins; Chromatography, High Pressure Liquid; Cross-Over Studies; Half-Life; Male; Metabolic Clearance Rate; Phenytoin; Rabbits; Sesquiterpenes | 2006 |
[The microfluorimetric assay (MFA) in in vitro testing the sensitivity of Plasmodium falciparum to antimalarial drugs].
Topics: Animals; Antimalarials; Artemether; Artemisinins; Chloroquine; Cytophotometry; Inhibitory Concentration 50; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrimethamine; Reproducibility of Results | 2006 |
From chloroquine to artemisinin-based combination therapy: the Sudanese experience.
Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Fluorenes; Health Policy; Humans; Lumefantrine; Malaria, Falciparum; Product Surveillance, Postmarketing; Pyrimethamine; Sesquiterpenes; Sudan; Sulfadoxine; Time Factors | 2006 |
[Extraction of artemisinin and synthesis of its derivates artesunate and artemether].
Topics: Artemether; Artemisinins; Artesunate; Chemistry, Pharmaceutical; Sesquiterpenes | 2006 |
Dissociative electron attachment to di-tert-butylperoxide, artemisinin, and beta-artemether.
Topics: Artemether; Artemisinins; Electrochemistry; Electrons; Peroxides | 2007 |
Resistance to artemisinin derivatives along the Thai-Cambodian border.
Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Cambodia; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Sesquiterpenes; Thailand | 2007 |
An efficient route into synthetically challenging bridged achiral 1,2,4,5-tetraoxanes with antimalarial activity.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Molecular Structure; Plasmodium falciparum; Structure-Activity Relationship; Tetraoxanes | 2008 |
Why don't health workers prescribe ACT? A qualitative study of factors affecting the prescription of artemether-lumefantrine.
Topics: Adult; Antimalarials; Artemether; Artemisinins; Case Management; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Government Programs; Guideline Adherence; Health Personnel; Humans; Kenya; Lumefantrine; Malaria; Male; Middle Aged; Rural Population; Surveys and Questionnaires | 2008 |
The use of artemether-lumefantrine by febrile children following national implementation of a revised drug policy in Kenya.
Topics: Anti-Infective Agents; Antimalarials; Artemether; Artemisinins; Child, Preschool; Cohort Studies; Cross-Sectional Studies; Drug Therapy, Combination; Ethanolamines; Fever; Fluorenes; Health Policy; Humans; Infant; Infant, Newborn; Kenya; Lumefantrine; Rural Health | 2008 |
A model based assessment of the CYP2B6 and CYP2C19 inductive properties by artemisinin antimalarials: implications for combination regimens.
Topics: Adult; Anticonvulsants; Antimalarials; Artemether; Artemisinins; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2C19; Drug Combinations; Enzyme Induction; Female; Genotype; Humans; Male; Mephenytoin; Models, Statistical; Oxidoreductases, N-Demethylating; Phenotype | 2008 |
Different methodological approaches to the assessment of in vivo efficacy of three artemisinin-based combination antimalarial treatments for the treatment of uncomplicated falciparum malaria in African children.
Topics: Africa; Amodiaquine; Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Child, Preschool; Databases as Topic; Drug Combinations; Ethanolamines; Fluorenes; Genotype; Humans; Infant; Lumefantrine; Malaria, Falciparum; Plasmodium falciparum; Polymerase Chain Reaction; Pyrimethamine; Sulfadoxine; Treatment Outcome | 2008 |
Developmental toxicity of artesunate in the rat: comparison to other artemisinins, comparison of embryotoxicity and kinetics by oral and intravenous routes, and relationship to maternal reticulocyte count.
Topics: Administration, Oral; Animals; Artemether; Artemisinins; Artesunate; Cesarean Section; Drug Administration Routes; Embryo Loss; Embryo, Mammalian; Female; Fetus; Injections, Intravenous; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Reticulocyte Count; Reticulocytes | 2008 |
Experimental therapy of hepatoma with artemisinin and its derivatives: in vitro and in vivo activity, chemosensitization, and mechanisms of action.
Topics: Animals; Antineoplastic Agents; Artemether; Artemisinins; Artesunate; Carcinoma, Hepatocellular; Cell Cycle; Cell Line, Tumor; Female; Gene Expression Regulation, Neoplastic; Humans; Liver; Liver Neoplasms; Mice; Mice, Nude; Xenograft Model Antitumor Assays | 2008 |
Advances in global biotechnology and local resources to treat malaria.
Topics: Antimalarials; Artemether; Artemisia; Artemisinins; Artesunate; Drug Approval; Drug Resistance, Multiple; Drugs, Investigational; Global Health; Humans; Malaria; Minnesota; Phytotherapy | 2009 |
Determination of beta-artemether and its main metabolite dihydroartemisinin in plasma employing liquid-phase microextraction prior to liquid chromatographic-tandem mass spectrometric analysis.
Topics: Animals; Artemether; Artemisinins; Calibration; Chemical Fractionation; Chemistry Techniques, Analytical; Chromatography, Liquid; Humans; Limit of Detection; Mass Spectrometry; Quality Control; Rats; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Toluene | 2010 |
Artemether and artesunate show the highest efficacies in rescuing mice with late-stage cerebral malaria and rapidly decrease leukocyte accumulation in the brain.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Brain; Leukocytes; Malaria, Cerebral; Mefloquine; Mice; Parasitemia; Plasmodium berghei; Quinine | 2011 |
Monitoring of artemisinin, dihydroartemisinin, and artemether in environmental matrices using high-performance liquid chromatography-tandem mass spectrometry (LC-MS/MS).
Topics: Artemether; Artemisia annua; Artemisinins; Chromatography, High Pressure Liquid; Kenya; Plant Extracts; Soil; Tandem Mass Spectrometry | 2011 |
Metabolite identification of artemether by data-dependent accurate mass spectrometric analysis using an LTQ-Orbitrap hybrid mass spectrometer in combination with the online hydrogen/deuterium exchange technique.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Bile; Chromatography, Liquid; Deuterium Exchange Measurement; Hydroxylation; Male; Mass Spectrometry; Methylation; Microsomes, Liver; Rats; Rats, Wistar; Tandem Mass Spectrometry | 2011 |
New treatment policy of malaria as a part of malaria control program in Indonesia.
Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Disease Eradication; Drug Resistance; Drug Therapy, Combination; Health Policy; Humans; Indonesia; Malaria, Falciparum; Malaria, Vivax; Practice Guidelines as Topic; Primaquine | 2012 |
Are artemisinin-based combination therapies effective against Plasmodium malariae?
Topics: Adult; Antimalarials; Artemether; Artemisinins; Drug Combinations; Ethanolamines; Fluorenes; HIV Infections; Humans; Lumefantrine; Malaria, Falciparum; Male; Plasmodium malariae; Treatment Failure | 2013 |
Structural insights into the theoretical model of Plasmodium falciparum NADH dehydrogenase and its interaction with artemisinin and derivatives: towards global health therapeutics.
Topics: Amino Acid Sequence; Antimalarials; Artemether; Artemisinins; Artesunate; Drug Design; Flavin-Adenine Dinucleotide; Global Health; Humans; Molecular Docking Simulation; Molecular Sequence Data; NADH Dehydrogenase; Plasmodium falciparum; Protein Binding; Protein Interaction Domains and Motifs; Protein Structure, Secondary; Protozoan Proteins; Sequence Homology, Amino Acid; Static Electricity; Thermodynamics; Tumor Protein, Translationally-Controlled 1 | 2013 |
Effects of artemisinin antimalarials on Cytochrome P450 enzymes in vitro using recombinant enzymes and human liver microsomes: potential implications for combination therapies.
Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C19; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Evaluation, Preclinical; Drug Interactions; Humans; Inhibitory Concentration 50; Microsomes, Liver; Recombinant Proteins; Tandem Mass Spectrometry | 2014 |
Detecting adenosine triphosphatase 6 (pfATP6) point mutations that may be associated with Plasmodium falciparum resistance to artemisinin: prevalence at baseline, before policy change in Uganda.
Topics: Anti-Infective Agents; Artemether; Artemisinins; Calcium-Transporting ATPases; Drug Resistance, Microbial; Drug Therapy, Combination; Ethanolamines; Fluorenes; Genotype; Humans; Lumefantrine; Malaria, Falciparum; Point Mutation; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Prevalence; Sequence Analysis, DNA; Uganda | 2011 |
The survival times of malaria-infected mice are prolonged more by several new two-carbon-linked artemisinin-derived dimer carbamates than by the trioxane antimalarial drug artemether.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Carbamates; Carbon; Crystallography, X-Ray; Dimerization; Drug Therapy, Combination; Malaria; Mefloquine; Mice; Molecular Conformation; Plasmodium berghei; Structure-Activity Relationship; Survival Analysis | 2014 |
A thiazole derivative of artemisinin moderately reduces Toxoplasma gondii cyst burden in infected mice.
Topics: Animals; Antiprotozoal Agents; Artemether; Artemisinins; Brain; Chronic Disease; Drug Stability; Female; Mice; Mice, Inbred CBA; Thiazoles; Toxoplasma; Toxoplasmosis, Animal | 2014 |
Fetal bovine serum and human constitutive androstane receptor: evidence for activation of the SV23 splice variant by artemisinin, artemether, and arteether in a serum-free cell culture system.
Topics: Artemether; Artemisinins; Biological Assay; Cell Culture Techniques; Cell Survival; Dose-Response Relationship, Drug; Genes, Reporter; Hep G2 Cells; Humans; Ligands; Protein Isoforms; Receptors, Androgen; Reproducibility of Results; Serum; Time Factors; Transfection | 2014 |
Quality of antimalarial drugs and antibiotics in Papua New Guinea: a survey of the health facility supply chain.
Topics: Amodiaquine; Amoxicillin; Antimalarials; Artemether; Artemisinins; Biosimilar Pharmaceuticals; Chloroquine; Drug Resistance; Health Facilities; Humans; Malaria, Falciparum; Malaria, Vivax; Papua New Guinea; Primaquine; Quality Control; Quinine | 2014 |
Interspecies allometric scaling of antimalarial drugs and potential application to pediatric dosing.
Topics: Age Factors; Antimalarials; Artemether; Artemisinins; Artesunate; Child; Child, Preschool; Female; Humans; Male; Models, Theoretical | 2014 |
The efficacy of artemisinin, artemether, and lumefantrine against Babesia gibsoni in vitro.
Topics: Anti-Infective Agents; Artemether; Artemisinins; Atovaquone; Babesia; Drug Resistance; Ethanolamines; Fluorenes; Lumefantrine | 2015 |
Gametocyte Clearance Kinetics Determined by Quantitative Magnetic Fractionation in Melanesian Children with Uncomplicated Malaria Treated with Artemisinin Combination Therapy.
Topics: Antimalarials; Artemether; Artemisinins; Child, Preschool; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Half-Life; Humans; Kinetics; Lumefantrine; Malaria, Falciparum; Malaria, Vivax; Male; Naphthoquinones; Plasmodium falciparum | 2015 |
Genetic Transformation of Artemisia carvifolia Buch with rol Genes Enhances Artemisinin Accumulation.
Topics: Agrobacterium tumefaciens; Antimalarials; Artemether; Artemisia annua; Artemisinins; Artesunate; Base Sequence; Biosynthetic Pathways; Gene Expression Regulation, Plant; Molecular Sequence Data; Plant Proteins; Plants, Genetically Modified; Transformation, Genetic; Trichomes | 2015 |
Pyrrolidine-Acridine hybrid in Artemisinin-based combination: a pharmacodynamic study.
Topics: Acridines; Animals; Antimalarials; Artemether; Artemisinins; Drug Resistance, Multiple; Drug Therapy, Combination; Lethal Dose 50; Malaria, Falciparum; Mice; Parasitemia; Plasmodium falciparum; Pyrrolidines | 2016 |
Endoperoxide Drug Cross-Resistance Patterns for Plasmodium falciparum Exhibiting an Artemisinin Delayed-Clearance Phenotype.
Topics: Adamantane; Antimalarials; Artemether; Artemisinins; Dose-Response Relationship, Drug; Drug Resistance; Heterocyclic Compounds, 1-Ring; Inactivation, Metabolic; Lethal Dose 50; Microbial Sensitivity Tests; Peroxides; Plasmodium falciparum; Spiro Compounds | 2016 |
[Elimination in South-East Asia? The role of antimalarial drugs].
Topics: Antimalarials; Artemether; Artemisinins; Asia, Southeastern; Disease Eradication; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Lumefantrine; Malaria, Falciparum; Quinolines | 2016 |
Level A in vitro-in vivo correlation: Application to establish a dissolution test for artemether and lumefantrine tablets.
Topics: Adolescent; Adult; Antimalarials; Artemether; Artemisinins; Ethanolamines; Female; Fluorenes; Humans; Lumefantrine; Malaria; Male; Middle Aged; Solubility; Tablets; Young Adult | 2018 |
Comparison of in vitro/in vivo blood distribution and pharmacokinetics of artemisinin, artemether and dihydroartemisinin in rats.
Topics: Administration, Oral; Animals; Antimalarials; Artemether; Artemisinins; Chromatography, Liquid; Drug Monitoring; Injections, Intravenous; Male; Rats, Sprague-Dawley; Tandem Mass Spectrometry; Tissue Distribution | 2019 |
Evaluation of the effects on the QT-interval of 4 artemisinin-based combination therapies with a correction-free and heart rate-free method.
Topics: Adolescent; Amodiaquine; Antimalarials; Arrhythmias, Cardiac; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Child, Preschool; Drug Combinations; Ethanolamines; Female; Fluorenes; Heart Rate; Humans; Long QT Syndrome; Malaria; Malaria, Falciparum; Male; Quinolines; Young Adult | 2019 |
Efavirenz-Based Antiretroviral Therapy Reduces Artemether-Lumefantrine Exposure for Malaria Treatment in HIV-Infected Pregnant Women.
Topics: Adolescent; Adult; Alkynes; Anti-HIV Agents; Anti-Retroviral Agents; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Benzoxazines; Cyclopropanes; Drug Combinations; Drug Interactions; Female; HIV Infections; Humans; Lumefantrine; Malaria; Malaria, Falciparum; Pregnancy; Prospective Studies; Uganda; Young Adult | 2020 |
Leishmania amazonensis response to artemisinin and derivatives.
Topics: Animals; Artemether; Artemisinins; Artesunate; Disease Models, Animal; Female; Leishmania mexicana; Mice; Mice, Inbred BALB C; Parasite Load; Trypanocidal Agents | 2021 |
Molecular Basis of Artemisinin Derivatives Inhibition of Myeloid Differentiation Protein 2 by Combined in Silico and Experimental Study.
Topics: Animals; Anti-Inflammatory Agents; Artemether; Artemisinins; Artesunate; Binding Sites; Cell Line; Cell Survival; Fatty Acid-Binding Proteins; Hydrophobic and Hydrophilic Interactions; Immunomodulation; In Vitro Techniques; Lipopolysaccharides; Lymphocyte Antigen 96; Mice; Microglia; Molecular Docking Simulation; Molecular Dynamics Simulation; Nitric Oxide; Protein Binding; Thermodynamics; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2021 |
Impact of Drug Exposure on Resistance Selection Following Artemether-Lumefantrine Treatment for Malaria in Children With and Without HIV in Uganda.
Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Drug Combinations; Fluorenes; HIV Infections; Humans; Lopinavir; Lumefantrine; Malaria; Malaria, Falciparum; Nevirapine; Ritonavir; Uganda | 2023 |
Exploring the Potential Mechanism of Artemisinin and Its Derivatives in the Treatment of Osteoporosis Based on Network Pharmacology and Molecular Docking.
Topics: Artemether; Artemisinins; Artesunate; Caspase 3; Drugs, Chinese Herbal; ErbB Receptors; Humans; Interleukin-17; Mitogen-Activated Protein Kinase 14; Molecular Docking Simulation; Network Pharmacology; Osteoporosis; Prolactin | 2022 |
Assessment of artemisinin tolerance in Plasmodium falciparum clinical isolates in children with uncomplicated malaria in Ghana.
Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Drug Combinations; Drug Tolerance; Ghana; Humans; Lumefantrine; Malaria; Malaria, Falciparum; Plasmodium falciparum | 2023 |
Anti-malarial drug use, appropriateness and associated factors among children under-five with febrile illnesses presenting to a tertiary health facility: a cross sectional study.
Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Child, Preschool; Cross-Sectional Studies; Fever; Humans; Malaria | 2023 |
Preventing antimalarial drug resistance with triple artemisinin-based combination therapies.
Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Folic Acid Antagonists | 2023 |
Therapeutic efficacy of artesunate-amodiaquine and artemether-lumefantrine for the treatment of uncomplicated falciparum malaria in Chad: clinical and genetic surveillance.
Topics: Adult; Amodiaquine; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Chad; Female; Humans; Malaria, Falciparum; Pregnancy; Prospective Studies | 2023 |
Healthcare provider and drug dispenser knowledge and adherence to guidelines for the case management of malaria in pregnancy in the context of multiple first-line artemisinin-based combination therapy in western Kenya.
Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Case Management; Cross-Sectional Studies; Female; Humans; Kenya; Malaria; Pregnancy; Quinine | 2023 |