Compounds > arsenic trioxide
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arsenic trioxide and fluorouracil

arsenic trioxide has been researched along with fluorouracil in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (26.32)29.6817
2010's10 (52.63)24.3611
2020's4 (21.05)2.80

Authors

AuthorsStudies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Li, JT; Ou, QJ; Wu, YC1
Kakehi, Y; Ogawa, O; Wu, XX1
Kaplow, R1
Han, JG; Li, BX; Xue, YW; Yang, BF1
Chung, WH; Kim, SS; Kuh, HJ; Rhim, H; Sung, BH1
Ardalan, B; Duncan, R; Fernandez, A; Ganjei-Azar, P; Gonzalez, M; Lee, K; Lima, M; Mezentsev, D; Podolsky, L; Ramos, Y; Reis, I; Subbarayan, PR1
Ardalan, B; Lee, K; Subbarayan, PR1
Ardalan, B; Francheschi, D; Livingstone, A; Oh, M; Podolsky, L; Subbarayan, PR1
Acalovschi, M; Aldea, M; Fischer-Fodor, E; Irimie, A; Kacso, G; Mosteanu, O; Petrushev, B; Pop, T; Soritau, O; Susman, S; Tomuleasa, C1
Allensworth, JL; Devi, GR; Diehl, AM; Lyerly, HK; Morse, MA; Rangwala, F; Smith, GR; Thomas, Z; Williams, KP1
Hirano, T; Onda, K; Sugiyama, K; Tanaka, S; Tohyama, N1
Beneytout, JL; Bertrand, J; Ghezali, L; Leger, DY; Liagre, B1
Jiang, F; Jiao, K; Ju, L; Li, Y; Li, Z; Liu, Q; Miao, L; Wang, Y1
Cao, Y; Cheng, JW; Fan, J; Hu, B; Huang, A; Huang, XW; Qiu, SJ; Sun, YF; Yang, XR; Zeng, HY; Zhang, X; Zhou, J1
Chen, L; Chen, W; Jiang, Q; Li, Q; Miao, L; Tang, L; Wang, Y; Xu, S; Yang, Y; Zhang, W1
Hu, Y; Li, S; Liu, H; Xie, Y; Xu, X; Yan, D; Zhao, Z; Zou, Y1

Reviews

2 review(s) available for arsenic trioxide and fluorouracil

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Innovations in antineoplastic therapy.
    The Nursing clinics of North America, 2005, Volume: 40, Issue:1

    Topics: Adjuvants, Immunologic; Alemtuzumab; Aminoglycosides; Anastrozole; Androstadienes; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Benzamides; Bile; Boronic Acids; Bortezomib; Capecitabine; Cetuximab; Decanoic Acids; Deoxycytidine; Docetaxel; Drug Approval; Estradiol; Fluorouracil; Fulvestrant; Gefitinib; Gemtuzumab; Humans; Imatinib Mesylate; Letrozole; Leuprolide; Nitriles; Oligopeptides; Organoplatinum Compounds; Oxaliplatin; Oxides; Piperazines; Polyesters; Pyrazines; Pyrimidines; Quinazolines; Taxoids; Thionucleotides; Tissue Extracts; Triazoles; United States; United States Food and Drug Administration; Vidarabine Phosphate

2005

Trials

1 trial(s) available for arsenic trioxide and fluorouracil

ArticleYear
A phase I study of 5-fluorouracil/leucovorin and arsenic trioxide for patients with refractory/relapsed colorectal carcinoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2010, Jun-01, Volume: 16, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Colorectal Neoplasms; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Oxides; Thymidylate Synthase

2010

Other Studies

16 other study(ies) available for arsenic trioxide and fluorouracil

ArticleYear
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
[Application of arsenic trioxide in comprehensive therapy of liver carcinoma].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2003, Volume: 23, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Carcinoma, Hepatocellular; Cisplatin; Doxorubicin; Female; Fluorouracil; Humans; Liver Neoplasms; Male; Middle Aged; Oxides

2003
Enhancement of arsenic trioxide-induced apoptosis in renal cell carcinoma cells by L-buthionine sulfoximine.
    International journal of oncology, 2004, Volume: 24, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Arsenic Trioxide; Arsenicals; Buthionine Sulfoximine; Carcinoma, Renal Cell; Caspases; Cell Division; Doxorubicin; Drug Synergism; Fluorouracil; Glutathione; Glutathione Transferase; Humans; Kidney Neoplasms; Oxidation-Reduction; Oxides; Tumor Cells, Cultured; Vinblastine

2004
[Reversal effect and mechanism of arsenic trioxide on multidrug resistance of gastric carcinoma cells SGC7901].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2007, Volume: 42, Issue:9

    Topics: Adenocarcinoma; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Epirubicin; Fluorouracil; Glutathione Transferase; Humans; Oxides; Stomach Neoplasms; Vincristine

2007
Synergistic interaction between tetra-arsenic oxide and paclitaxel in human cancer cells in vitro.
    International journal of oncology, 2009, Volume: 34, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Arsenic Trioxide; Arsenicals; bcl-2-Associated X Protein; Blotting, Western; Caspase 3; Cisplatin; Drug Interactions; Drug Synergism; Female; Fluorouracil; Head and Neck Neoplasms; Humans; In Vitro Techniques; Inhibitory Concentration 50; Oxides; Paclitaxel; Poly(ADP-ribose) Polymerases; Stomach Neoplasms; Tubulin; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Uterine Cervical Neoplasms

2009
Arsenic trioxide suppresses thymidylate synthase in 5-FU-resistant colorectal cancer cell line HT29 In Vitro re-sensitizing cells to 5-FU.
    Anticancer research, 2010, Volume: 30, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Blotting, Western; Colorectal Neoplasms; Drug Resistance, Neoplasm; Drug Synergism; Fluorouracil; Gene Expression; HT29 Cells; Humans; Oxides; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thymidylate Synthase; Tumor Suppressor Protein p53

2010
5-Fluorouracil/Leucovorin and arsenic trioxide for patients with refractory/relapsed colorectal carcinoma: a clinical experience.
    Acta oncologica (Stockholm, Sweden), 2011, Volume: 50, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Clinical Trials, Phase I as Topic; Colorectal Neoplasms; Drug Resistance, Neoplasm; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Neoplasm Recurrence, Local; Oxides; Treatment Outcome

2011
Arsenic trioxide plus cisplatin/interferon α-2b/doxorubicin/capecitabine combination chemotherapy for unresectable hepatocellular carcinoma.
    Hematology/oncology and stem cell therapy, 2011, Volume: 4, Issue:2

    Topics: AC133 Antigen; Antigens, CD; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Capecitabine; Carcinoma, Hepatocellular; Cell Line; Cisplatin; Deoxycytidine; Doxorubicin; Drug Resistance, Neoplasm; Fluorescent Dyes; Fluorouracil; Glycoproteins; Hep G2 Cells; Humans; Immunohistochemistry; Interferon-alpha; Liver Neoplasms; Oxides; Peptides; Rhodamine 123; Thy-1 Antigens

2011
Differential effects of arsenic trioxide on chemosensitization in human hepatic tumor and stellate cell lines.
    BMC cancer, 2012, Sep-10, Volume: 12

    Topics: Adult; AMP-Activated Protein Kinases; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Blotting, Western; Carcinoma, Hepatocellular; Cell Line; Cell Proliferation; Cell Survival; Drug Synergism; Enzyme Activation; Fluorouracil; Gene Expression Regulation, Enzymologic; Growth Inhibitors; Hep G2 Cells; Hepatic Stellate Cells; Humans; Inhibitory Concentration 50; Liver Neoplasms; Niacinamide; Oxides; Phenylurea Compounds; Reverse Transcriptase Polymerase Chain Reaction; Sorafenib; Thymidylate Synthase; Time Factors

2012
Influence of anticancer agents on cell survival, proliferation, and CD4+CD25+Foxp3+ regulatory T cell-frequency in human peripheral-blood mononuclear cells activated by T cell-mitogen.
    International immunopharmacology, 2013, Volume: 15, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Cell Proliferation; Cell Survival; Concanavalin A; Cytokines; Dacarbazine; Female; Fluorouracil; Humans; Immunosuppressive Agents; Leukocytes, Mononuclear; Male; Methotrexate; Mitogens; Oxides; T-Lymphocytes, Regulatory; Young Adult

2013
Cyclooxygenase-2 positively regulates Akt signalling and enhances survival of erythroleukemia cells exposed to anticancer agents.
    Apoptosis : an international journal on programmed cell death, 2013, Volume: 18, Issue:7

    Topics: Apoptosis; Arsenic Trioxide; Arsenicals; Casein Kinase II; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclooxygenase 2; Etoposide; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Erythroblastic, Acute; Oxides; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; RNA, Small Interfering; Signal Transduction; Staurosporine

2013
De-methylation of miR-148a by arsenic trioxide enhances sensitivity to chemotherapy via inhibiting the NF-κB pathway and CSC like properties.
    Experimental cell research, 2020, 01-15, Volume: 386, Issue:2

    Topics: 3' Untranslated Regions; Antineoplastic Agents; Arsenic Trioxide; Cell Line, Tumor; DNA Methylation; Drug Resistance, Neoplasm; Epigenesis, Genetic; Fluorouracil; Gene Expression Regulation, Neoplastic; Hepatocytes; Humans; MicroRNAs; Neoplastic Stem Cells; Oxaliplatin; Signal Transduction; Transcription Factor RelA

2020
Arsenic trioxide induces differentiation of cancer stem cells in hepatocellular carcinoma through inhibition of LIF/JAK1/STAT3 and NF-kB signaling pathways synergistically.
    Clinical and translational medicine, 2021, Volume: 11, Issue:2

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Cisplatin; Female; Fluorouracil; Humans; Janus Kinase 1; Leukemia Inhibitory Factor; Liver Neoplasms; Male; Mice, Inbred NOD; Mice, SCID; Neoplasm Transplantation; Neoplastic Stem Cells; NF-kappa B; Real-Time Polymerase Chain Reaction; Signal Transduction; STAT3 Transcription Factor

2021
The ATO/miRNA-885-5p/MTPN axis induces reversal of drug-resistance in cholangiocarcinoma.
    Cellular oncology (Dordrecht), 2021, Volume: 44, Issue:4

    Topics: Antineoplastic Agents; Arsenic Trioxide; Bile Duct Neoplasms; Cell Line; Cell Line, Tumor; Cell Survival; Cholangiocarcinoma; Cisplatin; Drug Resistance, Neoplasm; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Intercellular Signaling Peptides and Proteins; Kaplan-Meier Estimate; MicroRNAs; Signal Transduction

2021
Investigation of the Physical Properties and Clinical Application of Embosphere Microspheres.
    Chemotherapy, 2021, Volume: 66, Issue:4

    Topics: Angiography; Arsenic Trioxide; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Drug Carriers; Fluorouracil; Gelatin; Hepatic Artery; Humans; Liver Neoplasms; Microspheres; Oils; Particle Size

2021