Page last updated: 2024-08-26

arsenic and metallothionein

arsenic has been researched along with metallothionein in 113 studies

Research

Studies (113)

TimeframeStudies, this research(%)All Research%
pre-19903 (2.65)18.7374
1990's12 (10.62)18.2507
2000's46 (40.71)29.6817
2010's48 (42.48)24.3611
2020's4 (3.54)2.80

Authors

AuthorsStudies
Klaassen, CD1
Ehtechami, C; Elsenhans, B; Forth, W; Schmolke, G1
Lee, TC; Lo, JF; Tam, MF; Wang, HF1
Albores, A; Cherian, MG; Koropatnick, J; Zelazowski, AJ1
Aposhian, HV; Nelson, DL; Perry, DF; Zheng, W1
Batres, L; Carrizales, L; Díaz-Barriga, F; Mejía, JJ; Yáñez, L; Zanatta, MT1
Asano, M; Iwakura, Y; Kawade, Y; Nagashima, H1
Abe, M; Maitani, T; Saito, N; Saito, Y; Uchiyama, S1
Klaassen, CD; Kreppel, H; Liu, J; Liu, Y; Reichl, FX1
Chen, CL; Whanger, PD1
Phung, LT; Silver, S1
Hochadel, JF; Waalkes, MP1
Chan, KM; Chelius, M; Schlenk, D; Steevens, J; Wolford, L1
Flora, SJ; Tripathi, N1
Fulmer, BA; Hochadel, JF; Shimizu, M; Waalkes, MP1
Cebrián, ME; Del Razo, LM; Romach, EH; Waalkes, MP; Zhao, CQ1
Achanzar, W; Goyer, RA; Liu, J; Liu, Y; Waalkes, MP1
Brisbin, IL; Burger, J; Gaines, KF; Gochfeld, M; Lord, CG; McGrath, L; Yurkow, EJ1
Habeebu, SM; Klaassen, CD; Liu, J; Liu, Y; Waalkes, MP1
Falnoga, I; Jacimovic, R; Mazej, D; Scancar, J; Slejkovec, Z; Stibilj, E; Tusek-Znidaric, M1
Kadiiska, MB; Liu, J; Liu, Y; Lu, T; Qu, W; Waalkes, MP1
Bae, DS; Campain, JA; Carter, WH; Gennings, C; Yang, RS1
Klaassen, CD; Liu, Y; Park, JD1
Tamás, MJ; Wysocki, R1
Ishaque, AB; Schneider, J; Tchounwou, PB; Wilson, BA1
Albores, A; Brambila-Colombres, E; Calderón-Aranda, ES; Del Razo, LM; Manno, M; Quintanilla-Vega, B1
Baron, CL; Evans, RE; Klaverkamp, JF; Pedlar, RM; Ptashynski, MD; Wautier, KG1
Evans, R; Klaverkamp, JF; Pedlar, RM; Ptashynski, MD1
Butala, JH; Gordon, T; Li, P; Rossman, TG; Spanier, J1
Furst, A1
Hirayama, N; Murooka, Y; Toyama, M; Yamashita, M1
Abrahám, M; Ali, KS; Gazdag, AP; Hermesz, E; Nemcsók, J1
Bao, SF; Cheng, ZJ; Cong, T; Li, Z; Tian, H; Zhao, L1
Cullen, WR; Gong, Z; Jiang, G; Le, XC; Li, XF1
Dorsey, WC; Tchounwou, PB; Yedjou, CG1
Hara, S; Jimi, S; Suzumiya, J; Takaki, A; Uchiyama, M1
Merrifield, ME; Ngu, T; Stillman, MJ1
Ishida, Y; Kimura, A; Kondo, T; Mukaida, N; Wada, T; Yokoyama, H1
Charnock, JM; Langdon, CJ; Lee, PH; Meharg, AA; Morgan, AJ; Piearce, TG; Semple, KT; Stürzenbaum, SR; Winters, C1
Bhattacharya, S; Roy, S1
Bouskill, NJ; Ford, TE; Galloway, TS; Handy, RD1
Aposhian, HV; Aposhian, MM1
Garrett, SH; Namburi, VB; Sens, DA; Sens, MA; Singh, RK; Somji, S; Zhou, XD1
Garrett, SH; Gurel, V; Park, S; Sens, DA; Sens, MA; Somji, S; Zhou, XD1
Ngu, TT; Stillman, MJ1
Blomberg, J; Friman, G; Frisk, P; Gadhasson, IL; Ilbäck, NG; Mohamed, N1
Blasco, J; Delvalls, TA; Martín-Díaz, ML; Sales, D1
Fan, Y; Peng, L; Peng, Z; Shertzer, HG; Xia, Y; Zandi, E1
Flora, SJ; Gupta, R1
Cheng, ML; Dill, AL; Liu, J; Shan, KR; Shen, J; Waalkes, MP; Yang, Q; Zhang, X; Zhou, Y1
Alves, S; Capelo, JL; Costa, MH; Costa, PM; Diniz, MS; Peres, I; Santos, HM1
Benedetti, M; Fattorini, D; Gorbi, S; Moltedo, G; Notti, A; Regoli, F; Virno Lamberti, C1
Chen, W; Mulchandani, A; Singh, S1
Amlund, H; Boyle, D; Brix, KV; Bury, NR; Hogstrand, C; Lundebye, AK1
Cui, X; Okayasu, R1
Alves, S; Capelo-Martinez, JL; Costa, MH; Costa, PM; Diniz, MS; Peres, I; Santos, HM1
Easton, A; Ngu, TT; Stillman, MJ1
He, X; Ma, Q1
Le, XC; Li, XF; Lu, M; Lu, X; Wang, H1
Nordberg, GF1
Chen, L; Hong, F; Jin, T; Lei, L; Lu, J; Nordberg, GF; Nordberg, M; Wu, X1
Lee, JA; Ngu, TT; Rushton, MK; Stillman, MJ1
Lee, JA; Ngu, TT; Pinter, TB; Stillman, MJ1
Ferencz, A; Hermesz, E; Nemcsók, J; Said Ali, K1
Dryden, MD; Ngu, TT; Stillman, MJ1
Lin, J; Ma, Y; Ren, Y; Zhang, C1
Liu, J; Lu, YF; Shi, JS; Shi, JZ; Wu, Q; Yan, JW1
Gao, J; He, R; Li, J; Lu, Y; Peng, B1
Andrzejak, R; Antonowicz-Juchniewicz, J; Bizon, A; Milnerowicz, H1
Bocher, P; Bustamante, P; Churlaud, C; Cosson, RP; Lucia, M; Robin, F1
Falnoga, I; Marc, J; Mlakar, SJ; Šlejkovec, Z; Zajc, I; Zelenik Pevec, A; Žnidarič, MT1
Adhikari, B; Chakrabarty, D; Gautam, N; Tripathi, RD; Trivedi, PK; Verma, PK; Verma, S1
Perantoni, AO; Person, RJ; Sun, Y; Tokar, EJ; Waalkes, MP1
Calatayud, M; Devesa, V; Vélez, D1
Irvine, GW; Stillman, MJ; Summers, KL1
Cai, L; Li, W; Liu, Q; Miao, L; Miao, X; Su, G; Sun, W; Tan, Y; Tang, Z; Wang, Y; Wei, W1
Chang, PL; Chung, LC; Feng, TH; Juang, HH; Lee, YH; Sung, HC; Tsui, KH1
Cullen, WR; Le, XC; Li, XF; Shen, S; Weinfeld, M1
Bervoets, L; Blust, R; de Boeck, G; De Cock, H; Roggeman, S1
Bansal, MP; Ganger, R; Garg, ML; Garla, R; Mohanty, BP; Sudarshan, M1
Irvine, GW; Stillman, MJ1
Rodríguez-Sastre, MA; Rojas, E; Valverde, M1
Agrawal, S; Bhatnagar, P; Flora, G; Flora, SJ1
Adam, V; Dostalova, S; Kensova, R; Kizek, R; Konecna, M; Kremplova, M; Kudr, J; Moulick, A; Nejdl, L; Ruttkay-Nedecky, B; Skalickova, S1
Ilyas, S; Rehman, A1
Qu, W; Waalkes, MP1
Bell, MW; Makia, NL; Ngalame, NN; Person, RJ; Tokar, EJ; Waalkes, MP1
Adebambo, OA; Fry, RC; Ray, PD; Shea, D1
Ali, B; Ali, S; Farooq, MA; Gill, RA; Islam, F; Wang, J; Zhou, W1
Antunes, SC; Figueira, E; Freitas, R; Soares, AM; Velez, C1
Bordon, IC; Godoy, JM; Hauser-Davis, RA; Lavradas, RT; Rocha, RC; Saint'Pierre, TD1
Cui, Z; Liu, L; Ma, Q; Wang, Z; Xu, X1
Antonowicz-Juchniewicz, J; Bizoń, A; Milnerowicz, H; Milnerowicz, M; Śliwińska-Mossoń, M1
Bianchi, MS; Cabilla, JP; Duvilanski, BH; Ronchetti, SA1
Bansal, MP; Ganger, R; Garg, ML; Garla, R; Mohanty, BP; Verma, S1
Kang, JC; Kim, JH1
Cui, M; Hartley, W; Pan, W; Qin, Y; Shi, L; Wu, C; Wu, H; Xue, S1
Irvine, GW; Stillman, MJ; Tan, SN1
Almeida, Â; Chainho, P; Chiesa, S; Figueira, E; Freitas, R; Soares, AMVM1
Jiang, L; Li, G; Liu, Q; Meng, F; Wang, F; Zhou, R1
Chen, B; Jiang, X; Li, J; Sun, Y; Zhang, X1
Atia, AS; Darwish, WS; Eldin, WFS; Khedr, MHE1
Bihari, N; Cenov, A; Devescovi, M; Glad, M; Linšak, DT; Linšak, Ž; Lušić, DV; Perić, L; Traven, L; Žurga, P1
Gallagher, EP; Heffern, K; Tierney, K1
Barst, BD; Basu, N; Campbell, PGC; Drevnick, PE; Rosabal, M1
Huang, X; Li, J; Liang, Y; Lu, K; Ma, G; Pan, Y; Qiao, C; Qu, C; Wang, R; Wang, S; Xu, X; Zhu, M1
Mohammadzadeh, A; Shahpiri, A1
Chattopadhyay, S; Dash, M; Islam, SS; Maity, M; Perveen, H1
Bhattacharya, S; Chaudhuri, P; Das, S; Gachhui, R; Ghosh, S; Mukherjee, A; Mukherjee, J; Parvin, R; Roy, U; Roychowdhury, T; Sarkar, S1
Qi, Z; Tan, M; Wang, H; Wang, Q1
Amaro, F; de Francisco, P; Díaz, S; Gutiérrez, JC; Herráiz, M; Martín-González, A; Murciano, A; Rodríguez-Martín, D1
Gong, B; He, E; Peijnenburg, WJGM; Qiu, H; Wang, X1
Chakrabarty, D; Dutta, P; Gautam, N; Kidwai, M; Tiwari, M1

Reviews

6 review(s) available for arsenic and metallothionein

ArticleYear
Bacterial heavy metal resistance: new surprises.
    Annual review of microbiology, 1996, Volume: 50

    Topics: Arsenic; Bacteria; Biological Transport; Cadmium; Copper; Cyanobacteria; Drug Resistance, Microbial; Genes, Bacterial; Mercury; Metallothionein; Metals, Heavy; Organomercury Compounds

1996
Mechanisms involved in metalloid transport and tolerance acquisition.
    Current genetics, 2001, Volume: 40, Issue:1

    Topics: Animals; Antimony; Arsenic; Biological Transport, Active; Drug Resistance, Bacterial; Drug Resistance, Fungal; Drug Tolerance; Escherichia coli; Gene Expression; Glutathione; Humans; Leishmania; Metalloproteins; Metallothionein; Nematoda; Phytochelatins; Saccharomyces cerevisiae; Signal Transduction; Symbiosis; Trypanosoma

2001
Stress proteins induced by arsenic.
    Toxicology and applied pharmacology, 2001, Dec-01, Volume: 177, Issue:2

    Topics: Animals; Arsenic; Gene Expression Regulation; Heat-Shock Proteins; Heme Oxygenase (Decyclizing); HSP70 Heat-Shock Proteins; Humans; Membrane Proteins; Metallothionein; Oxidative Stress; Ubiquitin

2001
Arsenic toxicology: five questions.
    Chemical research in toxicology, 2006, Volume: 19, Issue:1

    Topics: Animals; Arsenic; Arsenic Poisoning; Arsenites; Aryl Hydrocarbon Hydroxylases; Chelating Agents; Cytochrome P-450 CYP2C19; Dimercaprol; Enzyme Inhibitors; Glutathione Transferase; Hemoglobins; Humans; Metallothionein; Methylation; Mixed Function Oxygenases; Polymorphism, Genetic; Protein Binding; Pyruvate Dehydrogenase Complex; Reactive Oxygen Species; Succimer; Unithiol

2006
Prevalence of kidney dysfunction in humans - relationship to cadmium dose, metallothionein, immunological and metabolic factors.
    Biochimie, 2009, Volume: 91, Issue:10

    Topics: Arsenic; Cadmium; Environmental Exposure; Humans; Kidney Diseases; Metallothionein

2009
Arsenic binding to proteins.
    Chemical reviews, 2013, Oct-09, Volume: 113, Issue:10

    Topics: Animals; Apoptosis; Arsenic; DNA Repair Enzymes; Hemoglobins; Metallothionein; Protein Binding; Proteins; Pyruvate Dehydrogenase Complex; Thioredoxins

2013

Other Studies

107 other study(ies) available for arsenic and metallothionein

ArticleYear
Effect of metallothionein on hepatic disposition of metals.
    The American journal of physiology, 1978, Volume: 234, Issue:1

    Topics: Animals; Arsenic; Cadmium; Copper; Injections, Subcutaneous; Lead; Liver; Male; Manganese; Mercury; Metalloproteins; Metallothionein; Methylmercury Compounds; Rats; Silver; Zinc

1978
Arsenic-copper interaction in the kidney of the rat.
    Human & experimental toxicology, 1992, Volume: 11, Issue:5

    Topics: Animals; Arsenic; Cadmium; Copper; Drug Interactions; Female; Kidney; Metallothionein; Rats; Rats, Sprague-Dawley

1992
Glutathione S-transferase pi in an arsenic-resistant Chinese hamster ovary cell line.
    The Biochemical journal, 1992, Dec-15, Volume: 288 ( Pt 3)

    Topics: Amino Acid Sequence; Animals; Arsenic; Arsenites; CHO Cells; Cricetinae; Drug Resistance; Electrophoresis, Polyacrylamide Gel; Glutathione Transferase; Heat-Shock Proteins; Humans; Isoenzymes; Metallothionein; Molecular Sequence Data; Rats; Sodium Compounds; Substrate Specificity; Sulfates; Zinc; Zinc Sulfate

1992
Arsenic induces and enhances rat hepatic metallothionein production in vivo.
    Chemico-biological interactions, 1992, Volume: 85, Issue:2-3

    Topics: Animals; Arsenic; Dose-Response Relationship, Drug; Liver; Male; Metallothionein; Protein Binding; Rats; Rats, Sprague-Dawley; RNA, Messenger; Time Factors; Zinc

1992
Choroid plexus protects cerebrospinal fluid against toxic metals.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1991, Volume: 5, Issue:8

    Topics: Animals; Arsenic; Blood Chemical Analysis; Cadmium; Cerebral Cortex; Cerebrospinal Fluid; Choroid Plexus; Cysteine; Dose-Response Relationship, Drug; Glutathione; Lead; Mercury; Metallothionein; Ouabain; Rats; Rats, Inbred Strains; Sodium-Potassium-Exchanging ATPase; Sulfhydryl Compounds

1991
Arsenic-cadmium interaction in rats: toxic effects in the heart and tissue metal shifts.
    Toxicology, 1991, Apr-08, Volume: 67, Issue:2

    Topics: Animals; Arsenic; Cadmium; Drug Interactions; Glutathione; Heart; Lethal Dose 50; Lipid Peroxidation; Male; Metallothionein; Myocardium; Rats; Rats, Inbred Strains

1991
Interferon production under the control of heterologous inducible enhancers and promoters.
    Microbiology and immunology, 1988, Volume: 32, Issue:6

    Topics: Animals; Arsenic; Arsenites; Cadmium; Cells, Cultured; DNA; Enhancer Elements, Genetic; Heat-Shock Proteins; Hot Temperature; Interferons; Kinetics; Metallothionein; Promoter Regions, Genetic

1988
Chemical form-dependent induction of hepatic zinc-thionein by arsenic administration and effect of co-administered selenium in mice.
    Toxicology letters, 1987, Volume: 39, Issue:1

    Topics: Animals; Arsenic; Liver; Male; Metallothionein; Mice; Mice, Inbred ICR; Selenium; Structure-Activity Relationship; Zinc

1987
Zinc-induced arsenite tolerance in mice.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1994, Volume: 23, Issue:1

    Topics: Animals; Arsenic; Arsenites; Male; Metallothionein; Mice; Mice, Inbred Strains; Radioisotopes; Zinc

1994
Interaction of selenium and arsenic with metallothionein: effect of vitamin B12.
    Journal of inorganic biochemistry, 1994, Volume: 54, Issue:4

    Topics: Animals; Arsenic; Arsenites; Cattle; Chromatography, Gel; Liver; Male; Metallothionein; Rats; Rats, Sprague-Dawley; Selenium; Sodium Selenite; Vitamin B 12; Vitamin B 12 Deficiency

1994
Sequence of exposure to cadmium and arsenic determines the extent of toxic effects in male Fischer rats.
    Toxicology, 1997, Jan-15, Volume: 116, Issue:1-3

    Topics: Animals; Arsenic; Cadmium; Chemical and Drug Induced Liver Injury; Drug Administration Schedule; Drug Interactions; Kidney Diseases; Male; Metallothionein; Necrosis; Rats; Rats, Inbred F344; Testis

1997
Effect of arsenite, arsenate, and the herbicide monosodium methyl arsonate (MSMA) on hepatic metallothionein expression and lipid peroxidation in channel catfish.
    Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology, 1997, Volume: 118, Issue:2

    Topics: Animals; Arsenates; Arsenic Poisoning; Arsenicals; Arsenites; Cadmium Chloride; Copper Sulfate; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Glutathione; Herbicides; Ictaluridae; Lipid Peroxidation; Liver; Male; Metallothionein; Sodium Compounds; Zinc Sulfate

1997
Hepatic and renal metallothionein induction following single oral administration of gallium arsenide in rats.
    Biochemistry and molecular biology international, 1998, Volume: 45, Issue:6

    Topics: Administration, Oral; Animals; Arsenicals; Gallium; Kidney; Liver; Male; Metallothionein; Rats; Rats, Wistar

1998
Effect of glutathione depletion and metallothionein gene expression on arsenic-induced cytotoxicity and c-myc expression in vitro.
    Toxicological sciences : an official journal of the Society of Toxicology, 1998, Volume: 45, Issue:2

    Topics: Animals; Arsenates; Arsenic; Arsenites; Cell Line; Gene Expression; Glutathione; Metallothionein; Proto-Oncogene Mas; Proto-Oncogene Proteins c-myc; Rats; Sodium Compounds

1998
Studies on the mechanisms of arsenic-induced self tolerance developed in liver epithelial cells through continuous low-level arsenite exposure.
    Toxicological sciences : an official journal of the Society of Toxicology, 2000, Volume: 54, Issue:2

    Topics: Animals; Animals, Newborn; Antimony; Arsenic; Cadmium; Cell Line; Cell Survival; Cisplatin; Drug Resistance; Epithelial Cells; Glutathione; Liver; Metallothionein; Mice; Mice, Transgenic; Nickel; Rats; Rats, Inbred F344

2000
Metallothionein-I/II null mice are more sensitive than wild-type mice to the hepatotoxic and nephrotoxic effects of chronic oral or injected inorganic arsenicals.
    Toxicological sciences : an official journal of the Society of Toxicology, 2000, Volume: 55, Issue:2

    Topics: Administration, Oral; Animals; Arsenic; Blood Urea Nitrogen; Caspase 3; Caspases; Chemical and Drug Induced Liver Injury; Female; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Injections, Subcutaneous; Interleukin-1; Interleukin-6; Kidney; Kidney Diseases; Liver; Male; Metallothionein; Mice; Mice, Knockout; Organ Size; Tumor Necrosis Factor-alpha

2000
Metals and metallothionein in the liver of raccoons: utility for environmental assessment and monitoring.
    Journal of toxicology and environmental health. Part A, 2000, Volume: 60, Issue:4

    Topics: Animals; Arsenic; Body Weight; Cesium Radioisotopes; Copper; Environmental Monitoring; Environmental Pollution; Flow Cytometry; Geography; Liver; Male; Manganese; Mercury; Metallothionein; Metals; Metals, Heavy; Predictive Value of Tests; Raccoons; Selenium; South Carolina; Strontium

2000
Chronic combined exposure to cadmium and arsenic exacerbates nephrotoxicity, particularly in metallothionein-I/II null mice.
    Toxicology, 2000, Jul-05, Volume: 147, Issue:3

    Topics: Acetylglucosaminidase; Administration, Oral; Animals; Arsenic; Body Weight; Cadmium; Drug Administration Schedule; Drug Synergism; Glycosuria; Kidney; Kidney Diseases; Liver; Male; Metallothionein; Mice; Mice, Knockout; Organ Size; Proteinuria

2000
Effect of arsenic trioxide on metallothionein and its conversion to different arsenic metabolites in hen liver.
    Biological trace element research, 2000,Winter, Volume: 78, Issue:1-3

    Topics: Animals; Arsenic; Arsenic Trioxide; Arsenicals; Biochemistry; Cadmium; Chickens; Copper; Female; Growth Inhibitors; Inactivation, Metabolic; Liver; Metallothionein; Methanol; Oxides; Selenium; Tissue Extracts; Zinc

2000
Stress-related gene expression in mice treated with inorganic arsenicals.
    Toxicological sciences : an official journal of the Society of Toxicology, 2001, Volume: 61, Issue:2

    Topics: Animals; Arsenicals; Arsenites; Blotting, Western; Cytochrome P-450 Enzyme System; DNA Damage; DNA-Binding Proteins; Down-Regulation; Endonucleases; GADD45 Proteins; Gene Expression Regulation; Heat-Shock Proteins; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Metallothionein; Mice; Mice, Inbred Strains; NF-kappa B; Oligonucleotide Array Sequence Analysis; Oxidative Stress; Proteins; Transcription Factor AP-1; Transcription Factor MTF-1; Transcription Factors

2001
Toxicological interactions among arsenic, cadmium, chromium, and lead in human keratinocytes.
    Toxicological sciences : an official journal of the Society of Toxicology, 2001, Volume: 63, Issue:1

    Topics: Arsenic; Cadmium; Cell Line, Transformed; Cell Survival; Chromium; Dose-Response Relationship, Drug; Drug Interactions; Glutathione; Humans; Keratinocytes; Lead; Metallothionein; Metals, Heavy

2001
Protective effect of metallothionein against the toxicity of cadmium and other metals(1).
    Toxicology, 2001, Jun-21, Volume: 163, Issue:2-3

    Topics: Animals; Arsenic; Cadmium; Cadmium Chloride; Copper; Dose-Response Relationship, Drug; Iron; Lead; Lethal Dose 50; Mercury; Metallothionein; Metals; Mice; Mice, Knockout; Zinc

2001
Atrazine potentiation of arsenic trioxide-induced cytotoxicity and gene expression in human liver carcinoma cells (HepG2).
    Molecular and cellular biochemistry, 2001, Volume: 222, Issue:1-2

    Topics: Arsenic Trioxide; Arsenicals; Atrazine; Cell Line, Transformed; Cell Survival; Cyclic AMP Response Element-Binding Protein; Drug Synergism; Endoplasmic Reticulum Chaperone BiP; Gene Expression; Gene Expression Profiling; Hepatocytes; HSP70 Heat-Shock Proteins; Humans; Liver Neoplasms; Metallothionein; Oxides; Proto-Oncogene Proteins c-fos

2001
The accumulation, distribution, and toxicological effects of dietary arsenic exposure in lake whitefish (Coregonus clupeaformis) and lake trout (Salvelinus namaycush).
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2002, Volume: 131, Issue:1

    Topics: Animals; Arsenic; Arsenic Poisoning; Diet; Eating; Gallbladder; Hemoglobins; Kidney; Liver; Metallothionein; Salmonidae; Tissue Distribution; Trout

2002
Toxicological effects of dietary arsenic exposure in lake whitefish (Coregonus clupeaformis).
    Aquatic toxicology (Amsterdam, Netherlands), 2002, Volume: 57, Issue:3

    Topics: Administration, Oral; Animal Feed; Animals; Arsenic; Cell Division; Environmental Exposure; Fibrosis; Gallbladder; Inflammation; Lipid Peroxidation; Liver; Metallothionein; Salmonidae; Tissue Distribution; Water Pollutants

2002
In vitro bioavailability of heavy metals in pressure-treated wood dust.
    Toxicological sciences : an official journal of the Society of Toxicology, 2002, Volume: 67, Issue:1

    Topics: Animals; Arsenates; Arsenic; Cell Line; Cell Survival; Chromium; Copper; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Dust; Fibroblasts; Metallothionein; Metals, Heavy; RNA, Messenger; Wood

2002
My saga with earthworms.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2002, Volume: 40, Issue:6

    Topics: Animals; Arsenicals; Benzene; Catalase; Glutathione Transferase; Metallothionein; Metals; Oligochaeta

2002
Interactions of arsenic with human metallothionein-2.
    Journal of biochemistry, 2002, Volume: 132, Issue:2

    Topics: Animals; Arsenic; Escherichia coli; Humans; Metallothionein; Molecular Weight; Protein Binding; Recombinant Fusion Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2002
Differential regulation of the two metallothionein genes in common carp.
    Acta biologica Hungarica, 2002, Volume: 53, Issue:3

    Topics: Animals; Arsenic; Base Sequence; Carps; Copper; DNA Primers; Gene Expression Regulation; Kidney; Liver; Metallothionein; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2002
[Influence of oral administration of realgar on contents of copper, zinc and selenium in rat tissues].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2001, Volume: 26, Issue:3

    Topics: Administration, Oral; Animals; Arsenicals; Copper; Kidney; Liver; Male; Materia Medica; Metallothionein; Random Allocation; Rats; Rats, Wistar; Selenium; Sulfides; Zinc

2001
Interaction of trivalent arsenicals with metallothionein.
    Chemical research in toxicology, 2003, Volume: 16, Issue:7

    Topics: Arsenic; Arsenicals; Cacodylic Acid; Chromatography, High Pressure Liquid; Metallothionein; Organometallic Compounds; Spectrometry, Mass, Electrospray Ionization

2003
Arsenic trioxide-induced transcriptional activation of stress genes and expression of related proteins in human liver carcinoma cells (HepG2).
    Cellular and molecular biology (Noisy-le-Grand, France), 2003, Volume: 49, Issue:7

    Topics: Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Cell Survival; Cloning, Molecular; Gene Expression Regulation, Neoplastic; Genes, Reporter; HSP70 Heat-Shock Proteins; Humans; Liver Neoplasms; Metallothionein; Oxides; Promoter Regions, Genetic; Proto-Oncogene Proteins c-fos; Transcriptional Activation; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2003
Mechanisms of cell death induced by cadmium and arsenic.
    Annals of the New York Academy of Sciences, 2004, Volume: 1011

    Topics: Animals; Arsenic; Cadmium; Cell Death; Cell Line; DNA Fragmentation; Dose-Response Relationship, Drug; Epithelial Cells; Glutathione; Humans; Kidney Tubules; Lipid Peroxidation; Membrane Potentials; Metallothionein; Mitochondria; Oxidation-Reduction; Rats

2004
Arsenic binding to Fucus vesiculosus metallothionein.
    Biochemical and biophysical research communications, 2004, Nov-05, Volume: 324, Issue:1

    Topics: Algal Proteins; Arsenic; Fucus; Humans; Metallothionein; Protein Binding; Spectrometry, Mass, Electrospray Ionization

2004
MRP-1 expression levels determine strain-specific susceptibility to sodium arsenic-induced renal injury between C57BL/6 and BALB/c mice.
    Toxicology and applied pharmacology, 2005, Feb-15, Volume: 203, Issue:1

    Topics: Animals; Arsenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Gene Expression Regulation; Glutathione; Kidney; Male; Metallothionein; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Multidrug Resistance-Associated Proteins; RNA-Binding Proteins; Species Specificity; Time Factors

2005
Ligand arsenic complexation and immunoperoxidase detection of metallothionein in the earthworm Lumbricus rubellus inhabiting arsenic-rich soil.
    Environmental science & technology, 2005, Apr-01, Volume: 39, Issue:7

    Topics: Animals; Arsenic; England; Histocytochemistry; Immunoenzyme Techniques; Ligands; Metallothionein; Oligochaeta; Soil; Spectrometry, X-Ray Emission; Spectrum Analysis; X-Ray Diffraction

2005
Arsenic-induced histopathology and synthesis of stress proteins in liver and kidney of Channa punctatus.
    Ecotoxicology and environmental safety, 2006, Volume: 65, Issue:2

    Topics: Animals; Arsenic Trioxide; Arsenicals; Blotting, Western; Creatinine; Glutathione; Glutathione Transferase; Heat-Shock Proteins; Kidney; Kidney Function Tests; Liver; Liver Function Tests; Metallothionein; Oxides; Perciformes; Water Pollutants, Chemical

2006
Differentiating copper and arsenic toxicity using biochemical biomarkers in Asellus aquaticus and Dreissena polymorpha.
    Ecotoxicology and environmental safety, 2006, Volume: 65, Issue:3

    Topics: Animals; Arsenic; Biomarkers; Copper; Dreissena; Gastrointestinal Tract; Gills; Isopoda; Metallothionein; Sodium-Potassium-Exchanging ATPase; Thiobarbituric Acid Reactive Substances; Water Pollutants, Chemical

2006
Metallothionein-1 and -2 expression in cadmium- or arsenic-derived human malignant urothelial cells and tumor heterotransplants and as a prognostic indicator in human bladder cancer.
    Toxicological sciences : an official journal of the Society of Toxicology, 2006, Volume: 91, Issue:2

    Topics: Animals; Arsenic; Biomarkers, Tumor; Cadmium; Carcinoma, Transitional Cell; Cell Line, Transformed; Gene Expression Regulation, Neoplastic; Humans; Metallothionein; Mice; Mice, Nude; Neoplasm Invasiveness; Neoplasm Transplantation; Prognosis; RNA, Messenger; Urinary Bladder Neoplasms; Urothelium

2006
Enhanced expression of metallothionein isoform 3 protein in tumor heterotransplants derived from As+3- and Cd+2-transformed human urothelial cells.
    Toxicological sciences : an official journal of the Society of Toxicology, 2006, Volume: 93, Issue:2

    Topics: Animals; Arsenic; Biomarkers, Tumor; Breast Neoplasms; Cadmium; Cell Transformation, Neoplastic; Cells, Cultured; Female; Humans; Immunohistochemistry; Male; Metallothionein; Metallothionein 3; Mice; Neoplasm Transplantation; Prostatic Neoplasms; Protein Isoforms; RNA, Messenger; Transplantation, Heterologous; Urinary Bladder Neoplasms

2006
Arsenic binding to human metallothionein.
    Journal of the American Chemical Society, 2006, Sep-27, Volume: 128, Issue:38

    Topics: Amino Acid Sequence; Arsenic; Humans; Kinetics; Metallothionein; Models, Molecular; Molecular Sequence Data; Protein Binding; Protein Structure, Tertiary; Spectrometry, Mass, Electrospray Ionization; Thermodynamics

2006
Virus induces metal-binding proteins and changed trace element balance in the brain during the course of a common human infection (coxsackievirus B3) in mice.
    The Science of the total environment, 2007, Aug-01, Volume: 381, Issue:1-3

    Topics: Animals; Arsenic; Brain; Cation Transport Proteins; Copper; Coxsackievirus Infections; Enterovirus B, Human; Female; Gene Expression Regulation; Mass Spectrometry; Mercury; Metallothionein; Metallothionein 3; Metals, Heavy; Mice; Mice, Inbred BALB C; Virus Replication; Zinc

2007
Biomarkers study for sediment quality assessment in spanish ports using the crab Carcinus maenas and the clam Ruditapes philippinarum.
    Archives of environmental contamination and toxicology, 2007, Volume: 53, Issue:1

    Topics: Animals; Arsenic; Biomarkers; Bivalvia; Brachyura; Cytochrome P-450 CYP1A1; Female; Geologic Sediments; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Metallothionein; Metals, Heavy; Polychlorinated Biphenyls; Polycyclic Aromatic Hydrocarbons; Spain; Water Pollutants, Chemical

2007
A critical role for IkappaB kinase beta in metallothionein-1 expression and protection against arsenic toxicity.
    The Journal of biological chemistry, 2007, Jul-20, Volume: 282, Issue:29

    Topics: 3T3 Cells; Animals; Antineoplastic Agents; Apoptosis; Arsenic; Arsenites; Gene Expression Regulation, Enzymologic; I-kappa B Kinase; MAP Kinase Kinase 4; Metallothionein; Mice; NF-kappa B; Reactive Oxygen Species; Signal Transduction

2007
Beneficial effects of Centella asiatica aqueous extract against arsenic-induced oxidative stress and essential metal status in rats.
    Phytotherapy research : PTR, 2007, Volume: 21, Issue:10

    Topics: Animals; Antioxidants; Arsenic; Centella; Copper; Glucosephosphate Dehydrogenase; Iron; Kidney; Liver; Male; Metallothionein; Oxidative Stress; Plant Extracts; Rats; Rats, Wistar; Triterpenes

2007
Blood metallothionein transcript as a biomarker for metal sensitivity: low blood metallothionein transcripts in arsenicosis patients from Guizhou, China.
    Environmental health perspectives, 2007, Volume: 115, Issue:7

    Topics: Animals; Arsenic; Base Sequence; Biomarkers; China; DNA Primers; Female; Humans; Male; Metallothionein; Polymerase Chain Reaction; Rats; Rats, Inbred F344; RNA, Messenger

2007
Toxicological effects and bioaccumulation in the freshwater clam (Corbicula fluminea) following exposure to trivalent arsenic.
    Environmental toxicology, 2007, Volume: 22, Issue:5

    Topics: Animals; Arsenic; Corbicula; Environmental Monitoring; Gastrointestinal Tract; Metallothionein; Water Pollutants, Chemical

2007
An ecotoxicological protocol with caged mussels, Mytilus galloprovincialis, for monitoring the impact of an offshore platform in the Adriatic Sea.
    Marine environmental research, 2008, Volume: 65, Issue:1

    Topics: Animals; Arsenic; Biomarkers; DNA Breaks, Single-Stranded; Environmental Monitoring; Enzymes; Glutathione; Lipofuscin; Mediterranean Region; Metallothionein; Metals, Heavy; Micronuclei, Chromosome-Defective; Mytilus; Oceans and Seas; Water Pollutants, Chemical

2008
Highly selective and rapid arsenic removal by metabolically engineered Escherichia coli cells expressing Fucus vesiculosus metallothionein.
    Applied and environmental microbiology, 2008, Volume: 74, Issue:9

    Topics: Aquaporins; Arsenic; Escherichia coli; Escherichia coli Proteins; Fucus; Metallothionein; Recombinant Proteins

2008
Natural arsenic contaminated diets perturb reproduction in fish.
    Environmental science & technology, 2008, Jul-15, Volume: 42, Issue:14

    Topics: Animals; Arsenic; Diet; Female; Fishes; Food Contamination; Male; Metallothionein; Metals; Polychaeta; Reproduction; Vitellogenins; Zebrafish

2008
Arsenic accumulation, elimination, and interaction with copper, zinc and manganese in liver and kidney of rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2008, Volume: 46, Issue:12

    Topics: Animals; Arsenic; Copper; Feces; Kidney; Liver; Male; Manganese; Metallothionein; Poisons; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tissue Distribution; Zinc

2008
Toxicokinetics of waterborne trivalent arsenic in the freshwater bivalve Corbicula fluminea.
    Archives of environmental contamination and toxicology, 2009, Volume: 57, Issue:2

    Topics: Algorithms; Animals; Arsenicals; Corbicula; Digestive System; Fresh Water; Metallothionein; Models, Biological; Water Pollutants, Chemical

2009
Kinetic analysis of arsenic-metalation of human metallothionein: significance of the two-domain structure.
    Journal of the American Chemical Society, 2008, Dec-17, Volume: 130, Issue:50

    Topics: Arsenic; Humans; Kinetics; Metallothionein; Models, Molecular; Protein Binding; Protein Structure, Tertiary; Spectrometry, Mass, Electrospray Ionization; Temperature

2008
Induction of metallothionein I by arsenic via metal-activated transcription factor 1: critical role of C-terminal cysteine residues in arsenic sensing.
    The Journal of biological chemistry, 2009, May-08, Volume: 284, Issue:19

    Topics: Animals; Arsenic; beta-Galactosidase; Blotting, Northern; Cells, Cultured; Chromatin Immunoprecipitation; Cysteine; DNA-Binding Proteins; Embryo, Mammalian; Fibroblasts; Immunoblotting; Liver Neoplasms, Experimental; Luciferases; Metallothionein; Mice; Mice, Knockout; NF-E2-Related Factor 2; Promoter Regions, Genetic; Reactive Oxygen Species; Response Elements; RNA, Messenger; Sulfhydryl Compounds; Transcription Factor MTF-1; Transcription Factors; Transcriptional Activation; Zinc

2009
Enzymatic digestion and chromatographic analysis of arsenic species released from proteins.
    Journal of chromatography. A, 2009, May-01, Volume: 1216, Issue:18

    Topics: Animals; Arsenates; Arsenic; Arsenites; Chromatography; Hemoglobins; Humans; Mass Spectrometry; Metallothionein; Peptide Hydrolases; Protein Binding; Rats

2009
Biomarkers of exposure, effects and susceptibility in humans and their application in studies of interactions among metals in China.
    Toxicology letters, 2010, Jan-15, Volume: 192, Issue:1

    Topics: Acetylglucosaminidase; Adult; Arsenic; beta 2-Microglobulin; Biomarkers; Cadmium; China; Environmental Exposure; Female; Humans; Kidney Tubules; Male; Metallothionein; Middle Aged

2010
Arsenic metalation of seaweed Fucus vesiculosus metallothionein: the importance of the interdomain linker in metallothionein.
    Biochemistry, 2009, Sep-22, Volume: 48, Issue:37

    Topics: Algal Proteins; Amino Acid Sequence; Arsenic; Fucus; Kinetics; Metallothionein; Molecular Sequence Data; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Spectrometry, Mass, Electrospray Ionization

2009
Arsenic-metalation of triple-domain human metallothioneins: Support for the evolutionary advantage and interdomain metalation of multiple-metal-binding domains.
    Journal of inorganic biochemistry, 2010, Volume: 104, Issue:3

    Topics: Amino Acid Sequence; Animals; Arsenic; Binding Sites; Biological Evolution; Humans; Metallothionein; Molecular Sequence Data; Protein Binding; Protein Conformation; Spectrometry, Mass, Electrospray Ionization

2010
Expressions of heat shock and metallothionein genes in the heart of common carp (Cyprinus carpio): effects of temperature shock and heavy metal exposure.
    Acta biologica Hungarica, 2010, Volume: 61, Issue:1

    Topics: Animals; Arsenic; Cadmium; Carps; Copper; Fever; Heart; Heat-Shock Proteins; Heat-Shock Response; Hypothermia; Metallothionein; Metals, Heavy; Temperature

2010
Arsenic transfer between metallothionein proteins at physiological pH.
    Biochemical and biophysical research communications, 2010, Oct-08, Volume: 401, Issue:1

    Topics: Arsenic; Cadmium; Enzyme Stability; Humans; Hydrogen-Ion Concentration; Ion Transport; Metallothionein; Recombinant Proteins; Spectrometry, Mass, Electrospray Ionization; Zinc

2010
Cd(II) and As(III) bioaccumulation by recombinant Escherichia coli expressing oligomeric human metallothioneins.
    Journal of hazardous materials, 2011, Jan-30, Volume: 185, Issue:2-3

    Topics: Arsenic; Base Sequence; Biopolymers; Cadmium; DNA Primers; Escherichia coli; Humans; Metallothionein; Recombination, Genetic

2011
Realgar- and cinnabar-containing an-gong-niu-huang wan (AGNH) is much less acutely toxic than sodium arsenite and mercuric chloride.
    Chemico-biological interactions, 2011, Jan-15, Volume: 189, Issue:1-2

    Topics: Alanine Transaminase; Animals; Arsenic; Arsenicals; Arsenites; Aspartate Aminotransferases; Blood Urea Nitrogen; Creatinine; Female; Kidney; Liver; Male; Medicine, Chinese Traditional; Mercuric Chloride; Mercury; Mercury Compounds; Metallothionein; Mice; Random Allocation; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium Compounds; Sulfides

2011
[Attenuation effects of compatible medicines on arsenical and lead toxicity of badu shengji san].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2011, Volume: 36, Issue:15

    Topics: Animals; Arsenic; Body Weight; Drugs, Chinese Herbal; Glutathione; Glutathione Peroxidase; Kidney; Lead; Male; Malondialdehyde; Metallothionein; Rats; Rats, Sprague-Dawley; Skin; Superoxide Dismutase

2011
The influence of the intensity of smoking and years of work in the metallurgy on pro-oxidant/antioxidant balance in the blood of smelters.
    Toxicology and industrial health, 2013, Volume: 29, Issue:2

    Topics: Adult; Arsenicals; Cadmium Compounds; Erythrocytes; Glutathione; Humans; Lead; Male; Malondialdehyde; Metallothionein; Metallurgy; Metals, Heavy; Middle Aged; Nicotiana; Occupational Exposure; Oxidative Stress; Oxidoreductases; Smoke; Smoking

2013
Insight on trace element detoxification in the Black-tailed Godwit (Limosa limosa) through genetic, enzymatic and metallothionein analyses.
    The Science of the total environment, 2012, Apr-15, Volume: 423

    Topics: Animals; Arsenic; Avian Proteins; Body Size; Charadriiformes; Diet; Feathers; Feeding Behavior; France; Gene Expression Regulation; Inactivation, Metabolic; Kidney; Liver; Metallothionein; Metals, Heavy; Molting; Muscles; Oxidative Stress; Selenium

2012
Arsenic trioxide (ATO) influences the gene expression of metallothioneins in human glioblastoma cells.
    Biological trace element research, 2012, Volume: 149, Issue:3

    Topics: Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Gene Expression; Glioblastoma; Humans; Metallothionein; Oxides

2012
Genome-wide identification of rice class I metallothionein gene: tissue expression patterns and induction in response to heavy metal stress.
    Functional & integrative genomics, 2012, Volume: 12, Issue:4

    Topics: Alternative Splicing; Amino Acid Sequence; Arsenic; Gene Expression Regulation, Developmental; Gene Expression Regulation, Plant; Genome, Plant; Metallothionein; Metals, Heavy; Molecular Sequence Data; Organ Specificity; Oryza; Plant Proteins; Stress, Physiological; Transcription, Genetic

2012
Chronic exposure of renal stem cells to inorganic arsenic induces a cancer phenotype.
    Chemical research in toxicology, 2013, Jan-18, Volume: 26, Issue:1

    Topics: AC133 Antigen; Animals; Antigens, CD; Arsenic; CD24 Antigen; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Cyclooxygenase 2; Glycoproteins; Humans; Kidney; Kidney Neoplasms; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Metallothionein; Mice; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplastic Stem Cells; Peptides; Rats; Stem Cells; Superoxide Dismutase; Superoxide Dismutase-1

2013
Differential toxicity and gene expression in Caco-2 cells exposed to arsenic species.
    Toxicology letters, 2013, Mar-27, Volume: 218, Issue:1

    Topics: Apoptosis; Arsenicals; Caco-2 Cells; Cacodylic Acid; Carcinogens, Environmental; Cell Survival; Gene Expression; Glutathione; Heat-Shock Proteins; Herbicides; Humans; Intestinal Mucosa; Lipid Peroxidation; Metallothionein; Mitochondria; Necrosis; Oxidative Stress; Oxidoreductases; Reactive Oxygen Species

2013
Cysteine accessibility during As3+ metalation of the α- and β-domains of recombinant human MT1a.
    Biochemical and biophysical research communications, 2013, Apr-19, Volume: 433, Issue:4

    Topics: Amino Acid Sequence; Arsenic; Benzoquinones; Cysteine; Escherichia coli; Humans; Metallothionein; Molecular Dynamics Simulation; Molecular Sequence Data; Protein Binding; Protein Folding; Protein Stability; Protein Structure, Tertiary; Recombinant Proteins; Spectrometry, Mass, Electrospray Ionization; Sulfhydryl Compounds

2013
Metallothionein prevention of arsenic trioxide-induced cardiac cell death is associated with its inhibition of mitogen-activated protein kinases activation in vitro and in vivo.
    Toxicology letters, 2013, Jul-18, Volume: 220, Issue:3

    Topics: Animals; Apoptosis; Arsenic Trioxide; Arsenicals; bcl-2-Associated X Protein; Blotting, Western; Caspase 3; Cell Line; Cell Survival; In Situ Nick-End Labeling; Male; Metallothionein; Mice; Mice, Transgenic; Mitogen-Activated Protein Kinases; Myocytes, Cardiac; Oxidative Stress; Oxides; Random Allocation; Rats; Transcription Factor CHOP

2013
Metallothionein 3: an androgen-upregulated gene enhances cell invasion and tumorigenesis of prostate carcinoma cells.
    The Prostate, 2013, Volume: 73, Issue:14

    Topics: Androgens; Animals; Arsenic; Cadmium; Carcinogenesis; Carcinoma; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Gene Expression Regulation, Neoplastic; Genetic Enhancement; Humans; Intracellular Signaling Peptides and Proteins; Male; Metallothionein; Metallothionein 3; Mice; Prostatic Neoplasms; Serpins; Signal Transduction; Up-Regulation

2013
Accumulation and detoxification of metals and arsenic in tissues of cattle (Bos taurus), and the risks for human consumption.
    The Science of the total environment, 2014, Jan-01, Volume: 466-467

    Topics: Animal Husbandry; Animals; Arsenic; Belgium; Cattle; Environmental Exposure; Environmental Monitoring; Female; Food Contamination; Humans; Inactivation, Metabolic; Mass Spectrometry; Metallothionein; Metals; Risk Assessment; Tissue Distribution

2014
Metal stoichiometry of isolated and arsenic substituted metallothionein: PIXE and ESI-MS study.
    Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 2013, Volume: 26, Issue:6

    Topics: Animals; Apoproteins; Arsenic; Binding Sites; Copper; Liver; Male; Metallothionein; Protein Binding; Rabbits; Rats; Rats, Wistar; Species Specificity; Spectrometry, Mass, Electrospray Ionization; Spectrometry, X-Ray Emission; Zinc

2013
Topographical analysis of As-induced folding of α-MT1a.
    Biochemical and biophysical research communications, 2013, Nov-08, Volume: 441, Issue:1

    Topics: Apoproteins; Arsenic; Benzoquinones; Humans; Metallothionein; Models, Molecular; Protein Folding; Recombinant Proteins; Solutions; Spectrometry, Mass, Electrospray Ionization; Titrimetry

2013
Assessing the impact of As-Cd-Pb metal mixture on cell transformation by two-stage Balb/c 3T3 cell assay.
    Mutagenesis, 2014, Volume: 29, Issue:4

    Topics: 3T3 Cells; Animals; Arsenic; Biological Assay; Cadmium; Cell Cycle; Cell Survival; Cell Transformation, Neoplastic; Cellular Senescence; DNA Damage; Humans; Lead; Metallothionein; Metals, Heavy; Mice; Mice, Inbred BALB C; Mutagenicity Tests; Reactive Oxygen Species

2014
Comparative oxidative stress, metallothionein induction and organ toxicity following chronic exposure to arsenic, lead and mercury in rats.
    Cellular and molecular biology (Noisy-le-Grand, France), 2014, Jun-22, Volume: 60, Issue:2

    Topics: Animals; Arsenic; Catalase; Glutathione; Glutathione Peroxidase; Kidney; Lead; Liver; Male; Mercury; Metallothionein; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase

2014
Interaction study of arsenic (III and V) ions with metallothionein gene (MT2A) fragment.
    International journal of biological macromolecules, 2015, Volume: 72

    Topics: Antineoplastic Agents; Arsenic; Communicable Diseases; DNA; DNA Fragmentation; Humans; Ions; Metallothionein; Spectrophotometry, Atomic

2015
Oxidative stress, glutathione level and antioxidant response to heavy metals in multi-resistant pathogen, Candida tropicalis.
    Environmental monitoring and assessment, 2015, Volume: 187, Issue:1

    Topics: Antioxidants; Arsenic; Cadmium; Candida tropicalis; Chromium; Copper; Environmental Monitoring; Glutathione; Metallothionein; Metals; Metals, Heavy; Oxidative Stress

2015
Metallothionein blocks oxidative DNA damage induced by acute inorganic arsenic exposure.
    Toxicology and applied pharmacology, 2015, Feb-01, Volume: 282, Issue:3

    Topics: Animals; Arsenic; Carcinogens; Cell Line; Cell Proliferation; Cell Survival; DNA Damage; DNA-Binding Proteins; Environmental Pollutants; Gene Expression Regulation; Glutathione Transferase; Heme Oxygenase-1; Isoenzymes; Membrane Proteins; Metallothionein; Mice; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Oxidative Stress; Transcription Factor MTF-1; Transcription Factors

2015
Chronic inorganic arsenic exposure in vitro induces a cancer cell phenotype in human peripheral lung epithelial cells.
    Toxicology and applied pharmacology, 2015, Jul-01, Volume: 286, Issue:1

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Arsenic; Carcinogens; Cell Line, Tumor; Cells, Cultured; Epithelial Cells; Epithelial-Mesenchymal Transition; Humans; Lung Neoplasms; Metallothionein; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phenotype; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins

2015
Toxicological responses of environmental mixtures: Environmental metal mixtures display synergistic induction of metal-responsive and oxidative stress genes in placental cells.
    Toxicology and applied pharmacology, 2015, Dec-15, Volume: 289, Issue:3

    Topics: Arsenic; Cadmium; Cell Line, Tumor; China; Dose-Response Relationship, Drug; Female; Heavy Metal Poisoning; Humans; Metallothionein; Metals, Heavy; Oxidative Stress; Placenta; Poisoning; Pregnancy; Water Pollutants, Chemical

2015
Subcellular distribution, modulation of antioxidant and stress-related genes response to arsenic in Brassica napus L.
    Ecotoxicology (London, England), 2016, Volume: 25, Issue:2

    Topics: Antioxidants; Arsenic; Biomass; Brassica napus; Dose-Response Relationship, Drug; HSP90 Heat-Shock Proteins; Metallothionein; Organelles; Oxidative Stress; Photosynthesis; Plant Proteins; Soil Pollutants; Tissue Distribution; Transcription, Genetic

2016
Clams sensitivity towards As and Hg: A comprehensive assessment of native and exotic species.
    Ecotoxicology and environmental safety, 2016, Volume: 125

    Topics: Animals; Antioxidants; Arsenic; Bivalvia; Catalase; Environmental Pollution; Europe; Glutathione Transferase; Mercury; Metallothionein; Superoxide Dismutase; Water Pollutants, Chemical

2016
Differential metallothionein, reduced glutathione and metal levels in Perna perna mussels in two environmentally impacted tropical bays in southeastern Brazil.
    Ecotoxicology and environmental safety, 2016, Volume: 129

    Topics: Animals; Arsenic; Bays; Brazil; Environmental Monitoring; Gastrointestinal Tract; Glutathione; Metallothionein; Metals; Muscles; Perna; Water Pollutants, Chemical

2016
Toxicological and biochemical responses of the earthworm Eisenia fetida exposed to contaminated soil: Effects of arsenic species.
    Chemosphere, 2016, Volume: 154

    Topics: Animals; Arsenates; Arsenic; Arsenic Poisoning; Arsenicals; Arsenites; Biomarkers; Biotransformation; Cacodylic Acid; Dose-Response Relationship, Drug; Environmental Pollution; Lipid Peroxidation; Lysosomes; Metallothionein; Oligochaeta; Oxidation-Reduction; Oxidative Stress; Soil; Soil Pollutants

2016
The effect of occupational exposure on pro/antioxidant balance in the blood of non-smoking and smoking smelters with diabetes.
    Environmental toxicology and pharmacology, 2016, Volume: 44

    Topics: Adult; Air Pollutants; Arsenic; Cadmium; Diabetes Mellitus; Environmental Monitoring; gamma-Glutamyltransferase; Glutathione; Glutathione Peroxidase; Glutathione Transferase; Humans; Lead; Male; Metallothionein; Metallurgy; Middle Aged; Occupational Exposure; Smoking; Superoxide Dismutase; Young Adult

2016
In Vivo and In Vitro Arsenic Exposition Induces Oxidative Stress in Anterior Pituitary Gland.
    International journal of toxicology, 2016, Volume: 35, Issue:4

    Topics: Animals; Apoptosis; Arsenic; Cell Survival; Cells, Cultured; Gene Expression; Male; Membrane Potential, Mitochondrial; Metallothionein; Oxidative Stress; Pituitary Gland, Anterior; Prolactin; Rats, Wistar; Reactive Oxygen Species; Thioredoxins; Water Pollutants, Chemical

2016
Metallothionein does not sequester arsenic(III) ions in condition of acute arsenic toxicity.
    Toxicology, 2016, 07-29, Volume: 366-367

    Topics: Animals; Arsenic; Arsenicals; Copper; Gene Expression Regulation; Liver; Male; Metallothionein; Rats; Rats, Wistar; RNA, Messenger; Toxicity Tests, Acute; Zinc

2016
The immune responses and expression of metallothionein (MT) gene and heat shock protein 70 (HSP 70) in juvenile rockfish, Sebastes schlegelii, exposed to waterborne arsenic (As
    Environmental toxicology and pharmacology, 2016, Volume: 47

    Topics: Acetylcholinesterase; Animals; Arsenic; Bass; Brain; Cholinesterase Inhibitors; Environmental Exposure; Fish Proteins; Gene Expression Regulation; HSP70 Heat-Shock Proteins; Hydrocortisone; Immunoglobulin M; Metallothionein; Muramidase; Water Pollutants, Chemical

2016
Cadmium, lead, and arsenic contamination in paddy soils of a mining area and their exposure effects on human HEPG2 and keratinocyte cell-lines.
    Environmental research, 2017, Volume: 156

    Topics: Arsenic; Cadmium; Cell Line; Cell Survival; China; Gene Expression Regulation; Hep G2 Cells; Humans; Keratinocytes; Lead; Metallothionein; Mining; Oryza; Soil Pollutants

2017
A Simple Metallothionein-Based Biosensor for Enhanced Detection of Arsenic and Mercury.
    Biosensors, 2017, Mar-13, Volume: 7, Issue:1

    Topics: Arsenic; Biosensing Techniques; Environmental Monitoring; Humans; Mercury; Metallothionein; Sensitivity and Specificity

2017
Metals and As content in sediments and Manila clam Ruditapes philippinarum in the Tagus estuary (Portugal): Impacts and risk for human consumption.
    Marine pollution bulletin, 2018, Volume: 126

    Topics: Animals; Arsenic; Bivalvia; Environmental Monitoring; Environmental Pollutants; Environmental Pollution; Estuaries; Food Contamination; Geologic Sediments; Humans; Metallothionein; Metals; Metals, Heavy; Portugal; Risk; Seafood; Water Pollutants, Chemical

2018
Assessment of metal contamination in estuarine surface sediments from Dongying City, China: Use of a modified ecological risk index.
    Marine pollution bulletin, 2018, Volume: 126

    Topics: Animals; Arsenic; Bivalvia; China; Ecology; Environmental Monitoring; Environmental Pollution; Geologic Sediments; Lysosomes; Mercury; Metallothionein; Metals, Heavy; Risk Assessment; Water Pollutants, Chemical

2018
Arbuscular mycorrhizal fungi alleviate arsenic toxicity to Medicago sativa by influencing arsenic speciation and partitioning.
    Ecotoxicology and environmental safety, 2018, Aug-15, Volume: 157

    Topics: Arsenic; Biomass; Glomeromycota; Medicago sativa; Metallothionein; Mycorrhizae; Phosphate Transport Proteins; Phosphorus; Plant Roots; Soil Pollutants; Symbiosis

2018
Metal contamination in quail meat: residues, sources, molecular biomarkers, and human health risk assessment.
    Environmental science and pollution research international, 2018, Volume: 25, Issue:20

    Topics: Animal Feed; Animals; Arsenic; Avian Proteins; Biomarkers; Coturnix; Drinking Water; Environmental Pollutants; Floors and Floorcoverings; Food Contamination; Gene Expression; HSP70 Heat-Shock Proteins; Humans; Kidney; Liver; Male; Meat; Metallothionein; Metals, Heavy; Muscles; Risk Assessment; RNA, Messenger; Tissue Distribution

2018
A baseline study of the metallothioneins content in digestive gland of the Norway lobster Nephrops norvegicus from Northern Adriatic Sea: Body size, season, gender and metal specific variability.
    Marine pollution bulletin, 2018, Volume: 131, Issue:Pt A

    Topics: Animals; Arsenic; Body Size; Croatia; Digestive System; Ecotoxicology; Female; Male; Mercury; Metallothionein; Metals; Nephropidae; Reactive Oxygen Species; Seasons; Shellfish; Water Pollutants, Chemical

2018
Comparative effects of cadmium, zinc, arsenic and chromium on olfactory-mediated neurobehavior and gene expression in larval zebrafish (Danio rerio).
    Aquatic toxicology (Amsterdam, Netherlands), 2018, Volume: 201

    Topics: Animals; Antioxidants; Arsenic; Behavior, Animal; Cadmium; Chromium; Gene Expression Regulation, Developmental; Larva; Metallothionein; Nervous System; Oxidative Stress; RNA, Messenger; Smell; Water Pollutants, Chemical; Zebrafish; Zebrafish Proteins; Zinc

2018
Subcellular distributions of trace elements (Cd, Pb, As, Hg, Se) in the livers of Alaskan yelloweye rockfish (Sebastes ruberrimus).
    Environmental pollution (Barking, Essex : 1987), 2018, Volume: 242, Issue:Pt A

    Topics: Alaska; Animals; Arsenic; Environmental Monitoring; Liver; Metallothionein; Metals, Heavy; Perciformes; Water Pollutants, Chemical

2018
Genome-Wide Characterization and Analysis of Metallothionein Family Genes That Function in Metal Stress Tolerance in
    International journal of molecular sciences, 2018, Jul-26, Volume: 19, Issue:8

    Topics: Amino Acid Sequence; Arsenic; Brassica napus; Gene Expression Regulation, Plant; Genome, Plant; Metallothionein; Phylogeny; Plant Proteins; Sequence Alignment; Stress, Physiological; Transcriptome

2018
Bioaccumulation of Arsenic by Engineered Escherichia coli Cells Expressing Rice Metallothionein Isoforms.
    Current microbiology, 2018, Volume: 75, Issue:11

    Topics: Arsenic; Escherichia coli; Genetic Engineering; Metallothionein; Oryza; Plant Proteins; Protein Isoforms; Recombinant Proteins

2018
Involvement of proinflammatory cytokines and metallothionein in the repairing of arsenic-mediated uterine tissue damage by curcumin.
    Journal of basic and clinical physiology and pharmacology, 2019, Jun-13, Volume: 30, Issue:4

    Topics: Animals; Antioxidants; Arsenic; Arsenites; Catalase; Curcumin; Cytokines; Female; Glutathione; Glutathione Peroxidase; Inflammation; Metallothionein; NF-kappa B; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Sodium Compounds; Superoxide Dismutase; Uterus

2019
Removal of Pb (II), As (III), and Cr (VI) by nitrogen-starved Papiliotrema laurentii strain RY1.
    Journal of basic microbiology, 2019, Volume: 59, Issue:10

    Topics: Antioxidants; Arsenic; Basidiomycota; Biodegradation, Environmental; Biological Transport; Cadmium; Environmental Pollutants; Gene Expression; Inactivation, Metabolic; Lead; Metallothionein; Metals, Heavy; Microbial Sensitivity Tests; Nitrogen

2019
Metallothionein Attenuated Arsenic-Induced Cytotoxicity: The Underlying Mechanism Reflected by Metabolomics and Lipidomics.
    Journal of agricultural and food chemistry, 2021, May-12, Volume: 69, Issue:18

    Topics: Animals; Arsenic; Humans; Lipidomics; Metabolomics; Metallothionein; Rats; Reactive Oxygen Species

2021
Arsenate and arsenite differential toxicity in Tetrahymena thermophila.
    Journal of hazardous materials, 2022, 06-05, Volume: 431

    Topics: Animals; Arsenates; Arsenic; Arsenites; Metallothionein; Tetrahymena thermophila

2022
Subcellular localization and compartment-specific toxicokinetics of cadmium, arsenic, and zinc in brandling worm Eisenia fetida.
    Chemosphere, 2022, Volume: 308, Issue:Pt 3

    Topics: Animals; Arsenic; Cadmium; Metallothionein; Metals; Oligochaeta; Soil; Soil Pollutants; Toxicokinetics; Zinc

2022
Functional characterization of rice metallothionein OsMT-I-Id: Insights into metal binding and heavy metal tolerance mechanisms.
    Journal of hazardous materials, 2023, 09-15, Volume: 458

    Topics: Arsenic; Cadmium; Cysteine; Metallothionein; Metals, Heavy; Oryza; Saccharomyces cerevisiae

2023