Page last updated: 2024-08-26

arsenic and buthionine sulfoximine

arsenic has been researched along with buthionine sulfoximine in 54 studies

Research

Studies (54)

TimeframeStudies, this research(%)All Research%
pre-19902 (3.70)18.7374
1990's8 (14.81)18.2507
2000's26 (48.15)29.6817
2010's18 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ballatori, N; Truong, AT1
Buchet, JP; Lauwerys, R1
Batres, L; Carrizales, L; Díaz-Barriga, F; Mejía, J; Ortíz, D; Ramos, O; Yáñez, L1
Huang, CF; Huang, H; Jan, KY; Jinn, CM; Wu, DR1
Cairns, J; Guy, GR; Ng, SB; Tan, YH1
Kaise, T; Ochi, T; Oya-Ohta, Y1
Akiyama, S; Chen, ZS; Furukawa, T; Haraguchi, M; Mutoh, M; Sumizawa, T; Tani, A1
Brigelius-Flohé, R; Friedrichs, B; Müller, C1
Chen, JC; Chen, YC; Kuo, ML; Yang, CH1
Cai, X; Chen, G; Shen, Y1
Cai, X; Chen, G; Chen, S; Huang, X; Jia, P; Shen, Y; Wang, L; Wang, Z; Yang, J; Yu, Y; Zhang, X; Zhou, L; Zhou, Y1
Cai, X; Huang, X; Zhou, Y1
Li, X; May, JM; Qu, ZC1
Akao, Y; Kito, M; Nozawa, Y; Ohishi, N; Yagi, K1
Chen, J; Guan, JY; Hour, TC; Huang, CY; Lu, SH; Pu, YS2
Cai, JF; Chiu, JF; Li, M1
Côté, S; Davison, K; Mader, S; Miller, WH1
Aller, P; Amrán, D; de Blas, E; Fernández, C; Ramos, AM; Sancho, P1
Hori, S; Kakehi, Y; Kakizuka, A; Maeda, H; Ogawa, O; Ohizumi, H; Segawa, T1
Kakehi, Y; Ogawa, O; Wu, XX1
Antony, S; Fu, H; Kohlhagen, G; Liao, Z; Liu, H; Pommier, Y; Sordet, O; Stevens, EV1
Fung, Y; Lin, B; Liu, D; Ma, X; Qin, J; Wang, W; Ye, N; Yu, L1
Engel, RH; Evens, AM1
Chow, J; Huang, M; Lee, C; Lin, C; Lin, Y; Liu, C; Liu, HE1
Chan, R; Chen, D; Jing, Y; Waxman, S1
Blower, P; Dai, Z; Huang, Y; Sadee, W1
Härtel, N; Hehlmann, R; Hochhaus, A; Konig, H; La Rosée, P; Lorentz, C; Melo, JV; Schatz, M; Schultheis, B1
Czyz, M; Duechler, M; Stańczyk, M; Stepnik, M1
Ma, LM; Qiao, ZH; Wang, HW; Wang, T; Yang, LH; Zhang, HP2
Han, YH; Kim, SH; Kim, SZ; Park, WH2
Kneifel, C; Lösler, S; Rojewski, MT; Schlief, S; Schrezenmeier, H; Thiel, E1
Boise, LH; Cai, Y; Croutch, C; Gutman, D; Lee, KP; Matulis, SM; Morales, AA; Yehiayan, L1
Biswas, S; Byrd, JC; Jarjoura, D; Mo, X; Mone, AP; Muthusamy, N; Vargo, M; Zhao, X1
Chan, SY; Ho, PC; Ong, PS1
Castellani, P; Ciriolo, MR; Delfino, L; Lucibello, M; Rubartelli, A; Venè, R1
Arai, M; Hikita, E; Hirano, T; Onda, K; Tanaka, S; Toyoda, H; Utsumi, H; Yuan, B1
Chen, BD; Feldmann, J; McGrath, SP; Uroic, MK; Xie, WY; Zhang, X; Zhao, FJ; Zhu, YG1
Requejo, R; Tena, M1
Chen, YC; Lee, WR; Shen, SC; Tsai, HH; Yang, LL; Yang, LY1
Park, WH; You, BR1
Doñate, F; Fruehauf, JP; Lee, K; Mazar, AP; Trapp, V1
Gonsebatt, ME; Valdovinos-Flores, C1
Fujii, Y; Komatsu, T; Shigemi, H; Tanaka, Y; Yamauchi, T1
Gülden, M; Klauser, E; Maser, E; Seibert, H; Seibert, S1
Bhattacharya, S; Chakraborty, A; Chattopadhyay, A; Srivastava, R1
Chen, Y; Ma, JF; McGrath, SP; Miller, AJ; Moore, KL; Zhao, FJ1
Li, X; Lin, L; Sun, GF; Wang, D1
Chen, C; Gu, S; Jiang, X; Zhang, Z1
Castrillo, G; García-Mina, JM; Hernández, LE; Leyva, A; Mateo, C; Mohan, TC; Muñoz, R; Navarro, C; Paz-Ares, J; Ramireddy, E; Schmülling, T; Zamarreño, AM; Zarco-Fernández, S1
Chou, YT; Pu, YS; Wang, AS1
Cai, QS; Hu, ZB; Li, DJ; Lou, LQ; Shi, GL1

Reviews

1 review(s) available for arsenic and buthionine sulfoximine

ArticleYear
Oxidative stress and apoptosis: a new treatment paradigm in cancer.
    Frontiers in bioscience : a journal and virtual library, 2006, Jan-01, Volume: 11

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Buthionine Sulfoximine; Cell Death; Dose-Response Relationship, Drug; Glutathione; Hexanones; Humans; Metalloporphyrins; Models, Biological; Models, Chemical; Neoplasms; Oxidation-Reduction; Oxidative Stress; Oxides; Reactive Oxygen Species

2006

Other Studies

53 other study(ies) available for arsenic and buthionine sulfoximine

ArticleYear
Relation between biliary glutathione excretion and bile acid-independent bile flow.
    The American journal of physiology, 1989, Volume: 256, Issue:1 Pt 1

    Topics: Aminopyrine; Animals; Arsenic; Arsenites; Benzylamines; Bile; Bile Acids and Salts; Buthionine Sulfoximine; Cefamandole; Furosemide; Glutathione; Glycocholic Acid; Kinetics; L-Lactate Dehydrogenase; Liver; Male; Methionine Sulfoximine; Nitrofurantoin; Phenobarbital; Rats; Rats, Inbred Strains; Sodium Compounds; Taurocholic Acid

1989
Role of thiols in the in-vitro methylation of inorganic arsenic by rat liver cytosol.
    Biochemical pharmacology, 1988, Aug-15, Volume: 37, Issue:16

    Topics: Animals; Arsenic; Arsenicals; Biotransformation; Buthionine Sulfoximine; Cacodylic Acid; Cytosol; Ketones; Liver; Methionine Sulfoximine; Methylation; Rats; Rats, Inbred Strains; Sulfhydryl Compounds

1988
Arsenic increased lipid peroxidation in rat tissues by a mechanism independent of glutathione levels.
    Environmental health perspectives, 1995, Volume: 103 Suppl 1

    Topics: Acetylcysteine; Animals; Arsenic; Buthionine Sulfoximine; Female; Glutamate-Cysteine Ligase; Glutathione; Lipid Peroxidation; Methionine Sulfoximine; Rats; Rats, Wistar

1995
Glutathione as a cellular defence against arsenite toxicity in cultured Chinese hamster ovary cells.
    Toxicology, 1993, May-24, Volume: 79, Issue:3

    Topics: Animals; Antimetabolites; Arsenic; Arsenites; Buthionine Sulfoximine; Cell Survival; CHO Cells; Chromosome Aberrations; Cricetinae; Cricetulus; Glutathione; Methionine Sulfoximine; Ultraviolet Rays

1993
Inactivation of a redox-sensitive protein phosphatase during the early events of tumor necrosis factor/interleukin-1 signal transduction.
    The Journal of biological chemistry, 1993, Jan-25, Volume: 268, Issue:3

    Topics: Amino Acid Sequence; Arsenic; Arsenites; Buthionine Sulfoximine; Cells, Cultured; Cytosol; Ethers, Cyclic; Fibroblasts; Heat-Shock Proteins; Heme Oxygenase (Decyclizing); Humans; Hydrogen Peroxide; Interleukin-1; Male; Methionine Sulfoximine; Molecular Sequence Data; Okadaic Acid; Oxidation-Reduction; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase Inhibitors; RNA, Messenger; Signal Transduction; Tumor Necrosis Factor-alpha

1993
Induction of chromosomal aberrations in cultured human fibroblasts by inorganic and organic arsenic compounds and the different roles of glutathione in such induction.
    Mutation research, 1996, Oct-25, Volume: 357, Issue:1-2

    Topics: Arsenicals; Buthionine Sulfoximine; Cells, Cultured; Chromosome Aberrations; Dose-Response Relationship, Drug; Fibroblasts; Glutathione; Humans; Mutagenesis; Sulfhydryl Reagents

1996
Reversal of heavy metal resistance in multidrug-resistant human KB carcinoma cells.
    Biochemical and biophysical research communications, 1997, Jul-30, Volume: 236, Issue:3

    Topics: Adenosine Triphosphate; Antimony; Antimony Potassium Tartrate; Arsenic; ATP-Binding Cassette Transporters; Buthionine Sulfoximine; Cyclic P-Oxides; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Enzyme Inhibitors; Glutamate-Cysteine Ligase; Glutathione; Glutathione Transferase; Humans; KB Cells; Metals, Heavy; Multidrug Resistance-Associated Proteins; Nicotinic Acids

1997
Inhibition of tumor necrosis factor-alpha- and interleukin-1-induced endothelial E-selectin expression by thiol-modifying agents.
    Arteriosclerosis, thrombosis, and vascular biology, 1998, Volume: 18, Issue:12

    Topics: Acetylcysteine; Arsenicals; Buthionine Sulfoximine; Cells, Cultured; E-Selectin; Endothelium, Vascular; Glutathione; Glutathione Disulfide; Humans; Interleukin-1; Sulfhydryl Compounds; Tumor Necrosis Factor-alpha

1998
Arsenic trioxide sensitivity is associated with low level of glutathione in cancer cells.
    British journal of cancer, 1999, Volume: 81, Issue:5

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Buthionine Sulfoximine; DNA-Binding Proteins; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Glutathione; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Isoenzymes; Multidrug Resistance-Associated Proteins; MutS Homolog 3 Protein; Oxides; Tumor Cells, Cultured

1999
[Glutathione synthesis inhibitor enhances arsenic trioxide-induced apoptosis].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 1999, Volume: 21, Issue:4

    Topics: Apoptosis; Arsenic Trioxide; Arsenicals; Buthionine Sulfoximine; Glutathione; Humans; Leukemia; Lymphoma; Oxides; Tumor Cells, Cultured

1999
Arsenic trioxide induces multiple myeloma cell apoptosis via disruption of mitochondrial transmembrane potentials and activation of caspase-3.
    Chinese medical journal, 2001, Volume: 114, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Buthionine Sulfoximine; Caspase 3; Caspases; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Membrane Potentials; Mitochondria; Multiple Myeloma; Oxides; Tretinoin; Tumor Cells, Cultured

2001
[Mechanisms of arsenic trioxide-induced apoptosis in myeloma cells].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2001, Volume: 23, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Buthionine Sulfoximine; Cell Division; Dithiothreitol; Drug Interactions; Humans; Interferon-alpha; Multiple Myeloma; Oxides; Tretinoin; Tumor Cells, Cultured

2001
GSH is required to recycle ascorbic acid in cultured liver cell lines.
    Antioxidants & redox signaling, 2001, Volume: 3, Issue:6

    Topics: Animals; Arsenicals; Ascorbic Acid; Buthionine Sulfoximine; Cell Line; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutathione; Humans; Kinetics; Liver; Maleates; NADP; Rats; Thioredoxin-Disulfide Reductase; Time Factors; Water

2001
Arsenic trioxide-induced apoptosis and its enhancement by buthionine sulfoximine in hepatocellular carcinoma cell lines.
    Biochemical and biophysical research communications, 2002, Mar-08, Volume: 291, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Buthionine Sulfoximine; Carcinoma, Hepatocellular; Caspases; Cell Division; Cell Nucleus; DNA Fragmentation; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Synergism; Glutathione; Humans; Kinetics; Liver Neoplasms; Oxides; Reactive Oxygen Species; Tumor Cells, Cultured

2002
Arsenic trioxide as a novel anticancer agent against human transitional carcinoma--characterizing its apoptotic pathway.
    Anti-cancer drugs, 2002, Volume: 13, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Buthionine Sulfoximine; Carcinoma, Transitional Cell; Caspase 3; Caspases; Cisplatin; DNA, Neoplasm; Drug Resistance, Neoplasm; Enzyme Activation; G1 Phase; Humans; Membrane Potentials; Mitochondria; Oxides; Reactive Oxygen Species; Signal Transduction; Tumor Cells, Cultured; Urinary Bladder Neoplasms

2002
Cytotoxicity of arsenic trioxide to transitional carcinoma cells.
    Urology, 2002, Volume: 60, Issue:2

    Topics: Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Buthionine Sulfoximine; Carcinoma, Transitional Cell; Cisplatin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Glutathione; Humans; Oxides; Tumor Cells, Cultured; Urinary Bladder Neoplasms

2002
Arsenic induces oxidative stress and activates stress gene expressions in cultured lung epithelial cells.
    Journal of cellular biochemistry, 2002, Volume: 87, Issue:1

    Topics: Animals; Antioxidants; Arsenic; Arsenites; Buthionine Sulfoximine; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Gene Expression; Genes, Immediate-Early; Glutamate-Cysteine Ligase; Glutathione; Lung; NF-kappa B; Oxidation-Reduction; Oxidative Stress; Protein Binding; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Reactive Oxygen Species; RNA, Messenger; Sodium Compounds; Time Factors; Transcription Factor AP-1; Transcription, Genetic; Transcriptional Activation; Up-Regulation

2002
Glutathione depletion overcomes resistance to arsenic trioxide in arsenic-resistant cell lines.
    Leukemia, 2003, Volume: 17, Issue:5

    Topics: Annexin A5; Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Buthionine Sulfoximine; Cell Division; Drug Resistance, Neoplasm; Electrophoretic Mobility Shift Assay; Glutathione; Humans; In Situ Nick-End Labeling; Leukemia, Promyelocytic, Acute; Neoplasm Proteins; Oncogene Proteins, Fusion; Oxides; Reactive Oxygen Species; Tumor Cells, Cultured

2003
12-O-tetradecanoylphorbol-13-acetate may both potentiate and decrease the generation of apoptosis by the antileukemic agent arsenic trioxide in human promonocytic cells. Regulation by extracellular signal-regulated protein kinases and glutathione.
    The Journal of biological chemistry, 2004, Jan-30, Volume: 279, Issue:5

    Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Buthionine Sulfoximine; Cadmium Chloride; Caspase 3; Caspases; Dose-Response Relationship, Drug; Doxorubicin; Enzyme Activation; Enzyme Inhibitors; Glutathione; Humans; Immunoblotting; Mitogen-Activated Protein Kinases; Monocytes; Oxides; p38 Mitogen-Activated Protein Kinases; Protein Kinase C; Tetradecanoylphorbol Acetate; Time Factors; U937 Cells

2004
Effective treatment of advanced solid tumors by the combination of arsenic trioxide and L-buthionine-sulfoximine.
    Cell death and differentiation, 2004, Volume: 11, Issue:7

    Topics: Animals; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Buthionine Sulfoximine; Cell Division; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance, Neoplasm; Drug Therapy, Combination; Female; Glutathione; HeLa Cells; Humans; Hydrogen Peroxide; Male; Mice; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms; Oxides; Prostatic Neoplasms; Reactive Oxygen Species; Transplantation, Heterologous; Xenograft Model Antitumor Assays

2004
Enhancement of arsenic trioxide-induced apoptosis in renal cell carcinoma cells by L-buthionine sulfoximine.
    International journal of oncology, 2004, Volume: 24, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Arsenic Trioxide; Arsenicals; Buthionine Sulfoximine; Carcinoma, Renal Cell; Caspases; Cell Division; Doxorubicin; Drug Synergism; Fluorouracil; Glutathione; Glutathione Transferase; Humans; Kidney Neoplasms; Oxidation-Reduction; Oxides; Tumor Cells, Cultured; Vinblastine

2004
Topoisomerase I-DNA complexes contribute to arsenic trioxide-induced apoptosis.
    The Journal of biological chemistry, 2004, Aug-06, Volume: 279, Issue:32

    Topics: Apoptosis; Arsenic Trioxide; Arsenicals; Blotting, Western; Buthionine Sulfoximine; Caspase 3; Caspase Inhibitors; Caspases; DNA; DNA Fragmentation; DNA Topoisomerases, Type I; Enzyme Activation; Enzyme Inhibitors; Flow Cytometry; Gene Expression; Gene Silencing; Humans; Leukemia; Oxides; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Recombinant Proteins; Tumor Cells, Cultured

2004
Simultaneous and ultrarapid determination of reactive oxygen species and reduced glutathione in apoptotic leukemia cells by microchip electrophoresis.
    Electrophoresis, 2005, Volume: 26, Issue:6

    Topics: Apoptosis; Arsenic Trioxide; Arsenicals; Buthionine Sulfoximine; Electrophoresis, Microchip; Fluorescent Dyes; Glutathione; Humans; Lasers; Leukemia, Promyelocytic, Acute; Miniaturization; Oxides; Reactive Oxygen Species; Reproducibility of Results; Rhodamines; Signal Transduction; Spectrometry, Fluorescence; Tumor Cells, Cultured

2005
Increased cellular glutathione and protection by bone marrow stromal cells account for the resistance of non-acute promylocytic leukemia acute myeloid leukemia cells to arsenic trioxide in vivo.
    Leukemia & lymphoma, 2006, Volume: 47, Issue:3

    Topics: Acute Disease; Animals; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Bone Marrow Cells; Buthionine Sulfoximine; Cell Count; Cell Line, Tumor; Coculture Techniques; Disease Models, Animal; Drug Resistance, Neoplasm; Glutathione; Humans; Injections, Intraperitoneal; Leukemia, Myeloid; Mice; Mice, Inbred NOD; Mice, SCID; Oxides; Stromal Cells; Treatment Failure

2006
Buthionine sulfoximine enhancement of arsenic trioxide-induced apoptosis in leukemia and lymphoma cells is mediated via activation of c-Jun NH2-terminal kinase and up-regulation of death receptors.
    Cancer research, 2006, Dec-01, Volume: 66, Issue:23

    Topics: Amino Acid Chloromethyl Ketones; Anthracenes; Apoptosis; Arsenic Trioxide; Arsenicals; Blotting, Western; Buthionine Sulfoximine; Caspase 3; Caspase Inhibitors; Cell Proliferation; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Glutathione; Humans; Hydrogen Peroxide; JNK Mitogen-Activated Protein Kinases; Jurkat Cells; Leukemia; Lymphoma; Oxides; Receptors, TNF-Related Apoptosis-Inducing Ligand; Time Factors; U937 Cells

2006
Chemoinformatics analysis identifies cytotoxic compounds susceptible to chemoresistance mediated by glutathione and cystine/glutamate transport system xc-.
    Journal of medicinal chemistry, 2007, Apr-19, Volume: 50, Issue:8

    Topics: Amino Acid Transport System y+; Antineoplastic Agents; Arsenicals; Benzoates; Buthionine Sulfoximine; Cell Line, Tumor; Computational Biology; Daunorubicin; Doxorubicin; Drug Resistance, Neoplasm; Glutathione; Glycine; Humans; Mannich Bases; Patulin; Stereoisomerism; Structure-Activity Relationship

2007
Enhanced Bcr-Abl-specific antileukemic activity of arsenic trioxide (Trisenox) through glutathione-depletion in imatinib-resistant cells.
    Haematologica, 2007, Volume: 92, Issue:6

    Topics: Arsenic Trioxide; Arsenicals; Benzamides; Buthionine Sulfoximine; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Synergism; Drug Therapy, Combination; Fusion Proteins, bcr-abl; Glutathione; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Oxides; Piperazines; Pyrimidines

2007
Potentiation of arsenic trioxide cytotoxicity by Parthenolide and buthionine sulfoximine in murine and human leukemic cells.
    Cancer chemotherapy and pharmacology, 2008, Volume: 61, Issue:5

    Topics: Adenosine Triphosphate; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Buthionine Sulfoximine; Cell Death; Cell Line, Tumor; DNA Fragmentation; Drug Synergism; Flow Cytometry; Glutamate-Cysteine Ligase; Glutathione; Humans; Leukemia; Mice; Microscopy, Fluorescence; NF-kappa B; Oxides; Reactive Oxygen Species; Sesquiterpenes

2008
[The effect of arsenic trioxide (As2O3) combined with BSO on K562/ADM cell and its mechanisms].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2007, Volume: 28, Issue:7

    Topics: Apoptosis; Arsenic Trioxide; Arsenicals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Buthionine Sulfoximine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Genes, MDR; Glutathione; Humans; K562 Cells; Oxides

2007
Enhancement of arsenic trioxide-induced apoptosis in HeLa cells by diethyldithiocarbamate or buthionine sulfoximine.
    International journal of oncology, 2008, Volume: 33, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Buthionine Sulfoximine; Cell Survival; Ditiocarb; Glutathione; HeLa Cells; Humans; Membrane Potential, Mitochondrial; Oxides; Reactive Oxygen Species; Superoxides

2008
Induction of apoptosis in arsenic trioxide-treated lung cancer A549 cells by buthionine sulfoximine.
    Molecules and cells, 2008, Aug-31, Volume: 26, Issue:2

    Topics: Apoptosis; Arsenic Trioxide; Arsenicals; Buthionine Sulfoximine; Cell Cycle; Cell Membrane; Cell Survival; Drug Resistance, Neoplasm; Drug Synergism; Glutathione; Humans; Lung Neoplasms; Membrane Potential, Mitochondrial; Oxides; Reactive Oxygen Species; Tumor Cells, Cultured

2008
[Arsenic trioxide combined with buthionine sulfoximine enhances apoptosis in multidrug-resistant human leukemia K562/ADM cells in vitro].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2008, Volume: 30, Issue:3

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Buthionine Sulfoximine; Cell Proliferation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Glutathione; Humans; K562 Cells; Oxides

2008
Antimony-trioxide- and arsenic-trioxide-induced apoptosis in myelogenic and lymphatic cell lines, recruitment of caspases, and loss of mitochondrial membrane potential are enhanced by modulators of the cellular glutathione redox system.
    Annals of hematology, 2009, Volume: 88, Issue:11

    Topics: Antimony; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Buthionine Sulfoximine; Caspase Inhibitors; Caspases; Cell Line, Tumor; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Glutathione; HL-60 Cells; Humans; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, T-Cell; Membrane Potential, Mitochondrial; Neoplasm Proteins; Oxidation-Reduction; Oxides

2009
Darinaparsin induces a unique cellular response and is active in an arsenic trioxide-resistant myeloma cell line.
    Molecular cancer therapeutics, 2009, Volume: 8, Issue:5

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Buthionine Sulfoximine; Cell Line, Tumor; Cell Survival; Cysteine; Drug Resistance, Neoplasm; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glutathione; Humans; Multiple Myeloma; Oxides

2009
Arsenic trioxide and ascorbic acid demonstrate promising activity against primary human CLL cells in vitro.
    Leukemia research, 2010, Volume: 34, Issue:7

    Topics: Amino Acid Chloromethyl Ketones; Amitrole; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Arsenic Trioxide; Arsenicals; Ascorbic Acid; B-Lymphocytes; Buthionine Sulfoximine; Catalase; Cell Line, Tumor; Cysteine Proteases; Cysteine Proteinase Inhibitors; Drug Evaluation, Preclinical; Drug Synergism; Enzyme Activation; Glutathione; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Neoplasm Proteins; Oxidants; Oxidative Stress; Oxides; Reactive Oxygen Species

2010
Differential augmentative effects of buthionine sulfoximine and ascorbic acid in As2O3-induced ovarian cancer cell death: oxidative stress-independent and -dependent cytotoxic potentiation.
    International journal of oncology, 2011, Volume: 38, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Buthionine Sulfoximine; Cell Death; Cell Line, Tumor; Drug Synergism; Female; Fibroblasts; Glutathione; Glutathione Peroxidase; Humans; Intracellular Space; Ovarian Neoplasms; Oxidative Stress; Oxides

2011
The cystine/cysteine cycle and GSH are independent and crucial antioxidant systems in malignant melanoma cells and represent druggable targets.
    Antioxidants & redox signaling, 2011, Nov-01, Volume: 15, Issue:9

    Topics: Antioxidants; Arsenic Trioxide; Arsenicals; Blotting, Western; Buthionine Sulfoximine; Cell Survival; Cysteine; Cystine; Glutathione; Glycine; HMGB1 Protein; Humans; Immunohistochemistry; Melanoma; Oxidation-Reduction; Oxides; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Tumor Cells, Cultured

2011
Effects of inorganic and organic arsenic compounds on growth and apoptosis of human T-lymphoblastoid leukemia cells.
    Anticancer research, 2011, Volume: 31, Issue:12

    Topics: Acetylcysteine; Apoptosis; Arsenic; Ascorbic Acid; Benzimidazoles; Buthionine Sulfoximine; Caspase 3; Caspase 7; Cell Line, Tumor; Cell Proliferation; Female; Humans; Inhibitory Concentration 50; Leukemia, T-Cell; Leukocytes, Mononuclear; Models, Chemical; Organic Chemicals; T-Lymphocytes; Tetrazolium Salts; Thiazoles

2011
Phytochelatins play a key role in arsenic accumulation and tolerance in the aquatic macrophyte Wolffia globosa.
    Environmental pollution (Barking, Essex : 1987), 2012, Volume: 165

    Topics: Adaptation, Physiological; Araceae; Arsenic; Biodegradation, Environmental; Buthionine Sulfoximine; Phytochelatins; Water Pollutants, Chemical

2012
Influence of glutathione chemical effectors in the response of maize to arsenic exposure.
    Journal of plant physiology, 2012, May-01, Volume: 169, Issue:7

    Topics: Arsenates; Arsenic; Arsenites; Biological Transport; Biomass; Buthionine Sulfoximine; Chelating Agents; Enzyme Inhibitors; Glutathione; Glutathione Transferase; Hydroponics; Phytochelatins; Plant Roots; Plant Shoots; Seedlings; Succimer; Sulfhydryl Compounds; Thiazoles; Unithiol; Zea mays

2012
Quercetin enhancement of arsenic-induced apoptosis via stimulating ROS-dependent p53 protein ubiquitination in human HaCaT keratinocytes.
    Experimental dermatology, 2012, Volume: 21, Issue:5

    Topics: Animals; Apoptosis; Arsenic; Buthionine Sulfoximine; Cell Line; Cell Survival; Fibroblasts; Humans; Keratinocytes; Leupeptins; Membrane Potential, Mitochondrial; Mice; Models, Animal; NIH 3T3 Cells; Peroxides; Quercetin; Reactive Oxygen Species; Tumor Suppressor Protein p53; Ubiquitination

2012
Arsenic trioxide induces human pulmonary fibroblast cell death via increasing ROS levels and GSH depletion.
    Oncology reports, 2012, Volume: 28, Issue:2

    Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; Apoptosis; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Buthionine Sulfoximine; Cell Death; Cell Line, Tumor; Fibroblasts; Glutathione; Humans; Lung; Oxides; Reactive Oxygen Species; Transfection

2012
Redox-related antimelanoma activity of ATN-224.
    Melanoma research, 2009, Volume: 19, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Buthionine Sulfoximine; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Disulfiram; Drug Synergism; Enzyme Inhibitors; Glutathione; Humans; Melanins; Melanoma; Molybdenum; Oxidation-Reduction; Oxides; Reactive Oxygen Species; Superoxide Dismutase; Temozolomide

2009
Nerve growth factor exhibits an antioxidant and an autocrine activity in mouse liver that is modulated by buthionine sulfoximine, arsenic, and acetaminophen.
    Free radical research, 2013, Volume: 47, Issue:5

    Topics: Acetaminophen; Animals; Antioxidants; Arsenic; Autocrine Communication; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Gene Expression Regulation; Liver; Mice; Nerve Growth Factor; Neurons; Oxidation-Reduction; Oxidative Stress; PC12 Cells; Phosphorylation; Rats; Receptor, trkA

2013
BIMEL is a key effector molecule in oxidative stress-mediated apoptosis in acute myeloid leukemia cells when combined with arsenic trioxide and buthionine sulfoximine.
    BMC cancer, 2014, Jan-15, Volume: 14

    Topics: Apoptosis; Apoptosis Regulatory Proteins; Arsenic Trioxide; Arsenicals; Bcl-2-Like Protein 11; Buthionine Sulfoximine; Drug Combinations; Gene Knockdown Techniques; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Membrane Proteins; Oxidative Stress; Oxides; Phosphorylation; Proto-Oncogene Proteins

2014
Additivity, antagonism, and synergy in arsenic trioxide-induced growth inhibition of C6 glioma cells: effects of genistein, quercetin and buthionine-sulfoximine.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2014, Volume: 67

    Topics: Animals; Arsenic Trioxide; Arsenicals; Brain Neoplasms; Buthionine Sulfoximine; Cell Division; Cell Line, Tumor; Genistein; Glioma; Oxides; Quercetin; Rats

2014
Differential in vivo genotoxicity of arsenic trioxide in glutathione depleted mouse bone marrow cells: expressions of Nrf2/Keap1/P62.
    Toxicology mechanisms and methods, 2015, Volume: 25, Issue:3

    Topics: Acetylcysteine; Adaptor Proteins, Signal Transducing; Animals; Arsenic Trioxide; Arsenicals; Bone Marrow Cells; Buthionine Sulfoximine; Chromatids; Chromosome Aberrations; Cytoskeletal Proteins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radical Scavengers; Gene Expression Regulation, Neoplastic; Glutamate-Cysteine Ligase; Glutathione; Kelch-Like ECH-Associated Protein 1; Male; Membrane Glycoproteins; Mice; Mutagens; Neoplasm Proteins; NF-E2-Related Factor 2; Nuclear Pore Complex Proteins; Oxides

2015
The role of nodes in arsenic storage and distribution in rice.
    Journal of experimental botany, 2015, Volume: 66, Issue:13

    Topics: Arsenic; Biological Transport; Buthionine Sulfoximine; Gene Expression Profiling; Gene Expression Regulation, Plant; Mutation; Organ Specificity; Oryza; Plant Proteins; Plant Stems; Spectrometry, X-Ray Emission

2015
Effects of glutathione on the in vivo metabolism and oxidative stress of arsenic in mice.
    The Journal of toxicological sciences, 2015, Volume: 40, Issue:5

    Topics: Animals; Antioxidants; Arsenic Poisoning; Arsenicals; Buthionine Sulfoximine; Chemoprevention; Female; Glutathione; Liver; Methylation; Mice; Oxidative Stress

2015
[Study on the resveratrol and arsenic trioxide combination induced apoptosis and its mechanism on lung adenocarcinoma cells].
    Wei sheng yan jiu = Journal of hygiene research, 2016, Volume: 45, Issue:1

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Anticarcinogenic Agents; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Arsenic Trioxide; Arsenicals; Buthionine Sulfoximine; Caspase 3; Drug Synergism; Glutathione; Humans; Lung Neoplasms; Membrane Potential, Mitochondrial; Mitochondria; Oxidation-Reduction; Oxides; Resveratrol; Stilbenes; Tumor Cells, Cultured

2016
Cytokinin Determines Thiol-Mediated Arsenic Tolerance and Accumulation.
    Plant physiology, 2016, Volume: 171, Issue:2

    Topics: Adaptation, Physiological; Arsenic; Buthionine Sulfoximine; Cytokinins; Down-Regulation; Gene Expression Regulation, Plant; Glutathione; Inactivation, Metabolic; Phenotype; Phytochelatins; Sulfhydryl Compounds; Up-Regulation

2016
Antagonistic effect of N-ethylmaleimide on arsenic-mediated oxidative stress-induced poly(ADP-ribosyl)ation and cytotoxicity.
    Journal of applied toxicology : JAT, 2017, Volume: 37, Issue:5

    Topics: Antidotes; Apoptosis; Arsenic Trioxide; Arsenicals; Buthionine Sulfoximine; Cell Line, Tumor; Cell Survival; Colony-Forming Units Assay; Comet Assay; DNA Damage; DNA Repair; Ethylmaleimide; Humans; Oxidative Stress; Oxides; Poly ADP Ribosylation

2017
Phytochelatins play key roles for the difference in root arsenic accumulation of different Triticum aestivum cultivars in comparison with arsenate uptake kinetics and reduction.
    Chemosphere, 2017, Volume: 175

    Topics: Arsenates; Arsenic; Buthionine Sulfoximine; Cysteine; Glutathione; Kinetics; Oxidation-Reduction; Phytochelatins; Plant Proteins; Plant Roots; Plant Shoots; Seedlings; Triticum

2017