arsenic has been researched along with ascorbic acid in 125 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (20.80) | 18.7374 |
| 1990's | 2 (1.60) | 18.2507 |
| 2000's | 52 (41.60) | 29.6817 |
| 2010's | 41 (32.80) | 24.3611 |
| 2020's | 4 (3.20) | 2.80 |
| Authors | Studies |
|---|---|
| Parker, D; Sommer, G; Turk, JL | 1 |
| Bhuvaneswaran, C; Wadkins, CL | 1 |
| Tanaka, I | 1 |
| Hiwasa, T; Sakiyama, S | 1 |
| Horio, T; Horiuti, Y; Nishikawa, K | 1 |
| Cowell, JL | 1 |
| Saris, NE; Wikström, MK | 1 |
| Asano, A; Brodie, AF; Hirata, H | 1 |
| Huang, CH; Mitchell, RA | 1 |
| Lindstedt, G; Lindstedt, S | 1 |
| Plank, WM | 1 |
| Boyd, ST; Douglas, F; Jones, C; Leary, PM | 1 |
| Morgan, EH | 1 |
| Coty, WA; Pedersen, PL | 1 |
| Mockel, JJ; Tyler, DD | 1 |
| Lindstedt, G; Lindstedt, S; Tofft, M | 1 |
| Harris, EJ | 1 |
| Chamalaun, RA; Tager, JM | 1 |
| Garland, PB; Shepherd, D; Yates, DW | 1 |
| May, JM; Mendiratta, S; Qu, ZC | 1 |
| Dai, J; Jing, Y; Waxman, S; Weinberg, RS | 1 |
| Bachleitner-Hofmann, T; Gisslinger, B; Gisslinger, H; Grumbeck, E | 1 |
| Chattopadhyay, S; Debnath, J; Ghosh, D; Ghosh, S | 1 |
| Bahlis, NJ; Boise, LH; Dalton, WS; Grad, JM; Oshiro, MM; Reis, I | 1 |
| Li, X; May, JM; Qu, ZC | 1 |
| Chopin, M; Dombret, H; Pierron, G; Poupon, J; Raffoux, E; Récher, C; Sigaux, F; Stern, MH | 1 |
| Gao, F; Li, H; Shi, G; Shi, X; Tang, X; Wang, Z; Yi, J | 1 |
| Deb, DK; Kalvakolanu, DV; Kambhampati, S; Minucci, S; Mohindru, M; Platanias, LC; Ravandi, F; Sassano, A; Verma, A | 1 |
| Dalton, WS | 1 |
| Bahlis, NJ; Boise, LH; Eckman, J; Fernandez, HF; Goodman, M; Jordan-McMurry, I; Kharfan-Dabaja, M; Lee, KP; McCafferty-Grad, J; Neil, J; Reis, I | 1 |
| Ravandi, F; van Besien, K | 1 |
| Kumaran, S; Panneerselvam, C; Ramanathan, K; Shila, S | 1 |
| EL-HEFNAWI, H; EL-NASR, HS | 1 |
| GOSWAMI, MN | 1 |
| GUILLORY, RJ | 1 |
| HORIO, T; KATSUMATA, M; NISHIKAWA, K; YAMASHITA, J | 1 |
| BANNISTER, WH | 1 |
| Bachelez, H; Degos, L; Dombret, H; Dubertret, L; Dupuy, A; Jean-Louis, F; Michel, L; Musette, P; Poupon, J; Sors, A; Viguier, M | 1 |
| Cobb, CE; May, JM; Qu, ZC | 1 |
| Flora, SJ; Kannan, GM | 1 |
| Hahm, ER; Han, SS; Jung, CW; Kim, K; Kim, WS; Kimler, BF; Lee, JH; Lee, MH; Lee, SJ; Park, CH; Park, HK; Park, K; Park, S; Riordan, HD; Riordan, NH; Surh, YJ; Yang, JH; Yoon, SS | 1 |
| Berenson, JR; Ferretti, D; Purner, MB; Swift, RA | 1 |
| Berenson, JR; Borad, MJ; Swift, R | 1 |
| Sekeres, MA | 1 |
| Cárcamo, JM; Golde, DW; Karasavvas, N; Stratis, G | 1 |
| Nandi, D; Patra, RC; Swarup, D | 1 |
| Bayard, R; Chatain, V; Gourdon, R; Moszkowicz, P; Sanchez, F | 1 |
| Engel, RH; Evens, AM | 1 |
| Del Razo, LM; Rojas, E; Soto-Reyes, E; Valverde, M | 1 |
| Duke, J; El-Kadi, AO; Elbekai, RH | 1 |
| Abou-Jawde, RM; Andresen, S; Baz, R; Hussein, M; Karam, MA; Kelly, M; Reed, J; Walker, E | 1 |
| Bok Jung, H; Zheng, Y | 1 |
| Fu, Q; Hu, BR; Li, JJ; Li, Y; Ming, ZY; Qian, JQ; Tang, Q; Xiang, JZ | 1 |
| Gokhalé, P; Morrison, MJ; Patel, T; Vissers, MC | 1 |
| Berenson, JR; Bessudo, A; Boccia, R; Bozdech, M; Ferretti, D; Flam, M; Jilani, S; Louie, R; Lutzky, J; Moss, R; Patel, R; Russell, K; Siegel, D; Stadtmauer, E; Steis, R; Swift, RA; Talisman Pomeroy, J; Volk, J; Wong, SF; Yeh, HS | 1 |
| Amadori, S; Beksac, M; Sonneveld, P; van Droogenbroeck, J; Wu, KL; Zweegman, S | 1 |
| Chang, SI; Jin, B; Park, C; Park, JD; Ryu, DY; Youn, P | 1 |
| Berenson, JR; Mapes, R; Matous, J; Morrison, B; Swift, RA; Yeh, HS | 1 |
| Rana, SV | 1 |
| Ardalan, B; Lima, M; Subbarayan, PR | 1 |
| Flora, G; Flora, SJ; Mishra, M; Saxena, G | 1 |
| Baritaki, S; Berenson, JR; Bonavida, B; Campbell, RA; Chen, H; Gordon, M; Pang, S; Said, J; Sanchez, E; Shalitin, D; Steinberg, JA; Wang, C | 1 |
| Falnoga, I; Podgornik, H; Pucer, A; Slejkovec, Z; Tusek-Znidaric, M | 1 |
| Rana, SV; Singh, S | 2 |
| Cobb, CE; Li, L; May, JM; Qu, ZC | 1 |
| Bael, TE; Gollob, JA; Peterson, BL | 1 |
| Hu, J; Shu, C; Xu, W; Ye, Y | 1 |
| Adeloju, SB; Zhang, Y | 1 |
| Ahuja, HG; Bailey, HH; Chang, JE; Kahl, BS; Kim, K; Kolesar, JM; Rodriguez, GA; Sanchez, FA; Voorhees, PM; Werndli, J | 1 |
| Ahsan, H; Chen, Y; Graziano, JH; Howe, GR; Parvez, F; van Geen, A; Zablotska, LB | 1 |
| Banerjee, P; Belon, P; Bhattacharjee, N; Bhattacharyya, SS; Boujedaini, N; Khuda-Bukhsh, AR; Pathak, S | 1 |
| Datta, R; Makris, KC; Nagar, R; Quazi, S; Sarkar, D; Sylvia, VL | 1 |
| Grzanka, A; Izdebska, M; Litwiniec, A; Szczepański, MA | 1 |
| FRIEND, FJ; IVY, AC | 1 |
| Alousi, A; Anderlini, P; Champlin, RE; Giralt, S; Hosing, C; Jones, RB; Khan, FB; Mendoza, F; Nieto, Y; Parikh, G; Pelosini, M; Popat, U; Qazilbash, MH; Saliba, RM; Wang, M; Weber, DM | 1 |
| Corti, A; Favini, E; Giommarelli, C; Paolicchi, A; Pompella, A; Supino, R; Zunino, F | 1 |
| Hong, Y; Li, S; Liu, P; Piao, F; Wang, Y; Zhao, Y | 1 |
| Das, J; Ghosh, J; Manna, P; Sil, PC; Sinha, M | 1 |
| Bhadauria, S; Prathapan, A; Raghu, KG; Sharma, S; Singh, R; Yadav, GK | 1 |
| Biswas, S; Byrd, JC; Jarjoura, D; Mo, X; Mone, AP; Muthusamy, N; Vargo, M; Zhao, X | 1 |
| Bandyopadhyay, S; Bera, AK; Bhattacharya, D; Das, S; Das, SK; De, S; Pan, D; Rana, T | 1 |
| ORTIZ CANO, C | 1 |
| Amachi, S; Dong, D; Makino, T; Nakamura, T; Takahashi, Y; Yamaguchi, N | 1 |
| Chan, SY; Ho, PC; Ong, PS | 1 |
| Abboud, CN; Cashen, AF; DiPersio, JF; Gao, F; Hassan, A; Klco, JM; Procknow, E; Stockerl-Goldstein, KE; Uy, GL; Vij, R; Welch, JS; Westervelt, P | 1 |
| Falnoga, I; Slejkovec, Z; van Elteren, JT; Zelenik Pevec, A | 1 |
| Khare, PB; Pandey, AK; Raj, A; Sharma, YK; Singh, N; Srivastava, PK | 1 |
| Bashir, Q; Bassett, RL; Champlin, RE; Giralt, SA; Hosing, CM; Khan, H; Orlowski, RZ; Parmar, S; Popat, UR; Qazilbash, MH; Shah, JJ; Shah, N; Sharma, M; Thall, PF; Wang, M | 1 |
| Au, WY; Kumana, CR; Kwong, YL; Lau, JS; Lee, HK; Lin, SY; Liu, H; Yeung, DY | 1 |
| Advani, A; Bejanyan, N; Chan, J; Jankowska, A; Kalaycio, M; Maciejewski, JP; Mooney, L; Raza, A; Saunthararajah, Y; Sekeres, MA; Tiu, RV | 1 |
| Arai, M; Hikita, E; Hirano, T; Onda, K; Tanaka, S; Toyoda, H; Utsumi, H; Yuan, B | 1 |
| Cao, M; Feng, L; Hu, C; Ma, X; Zhu, Y | 1 |
| Park, WH; You, BR | 1 |
| Cilloni, D; Galimberti, S; Gioia, D; Guerrini, F; Levis, A; Messa, E; Palumbo, GA; Petrini, I; Petrini, M; Salvi, F | 1 |
| Chao, NJ; de Castro, CM; Diehl, LF; Gasparetto, C; Gockerman, JP; Held, LA; Horwitz, ME; Long, GD; Moore, JO; Rizzieri, D | 1 |
| Antonio, MT; Herrera, A; Pineda, J | 1 |
| Prasad, SM; Singh, VP; Srivastava, PK | 1 |
| Dey, A; Mukherjee, S; Mukhopadhyay, PK; Pradhan, NK | 1 |
| Prabu, SM; Sumedha, NC | 1 |
| Brandt-Rauf, P; Cassai, N; Dinnen, RD; Fine, RL; Mao, Y; Nichols, G; Qiu, W; Slavkovich, VN; Su, GH | 1 |
| Hsu, WH; Jiang, SJ; Sahayam, AC | 1 |
| Garg, SK; Mandil, R; Prakash, A; Rahal, A; Rajpoot, DS | 1 |
| Barral, MT; Calvo, V; Iglesias, L; Rubinos, DA | 1 |
| Aldoss, I; Douer, D; Mark, L; Mohrbacher, AM; Ramezani, L; Vrona, J; Weitz, I | 1 |
| Ferencz, Á; Hermesz, E; Horváth, E; Krisch, J; Máté, Z; Papp, A; Paulik, E; Sárközi, K; Szabó, A | 1 |
| Baek, K; Kim, EJ; Lee, JC | 2 |
| Chen, TY; Chen, ZG; Gao, X; Huang, CW; Huang, XC; Li, ZB; Maimaiti, XY; Zhang, L | 1 |
| Ajvazi, M; Daci, N; Kurti, L; Sekovanić, A; Zeneli, L | 1 |
| Bhadra, RK; Biswas, S; Chatterjee, A; Mishra, R; Mondal, R; Mukhopadhyay, A; Mukhopadhyay, PK | 1 |
| Augustine, R; Bisht, NC; Gupta, M; Pandey, C; Panthri, M; Zia, I | 1 |
| Corpas, FJ; Feriche-Linares, R; Palma, JM; Rodríguez-Ruíz, M; Ruíz-Torres, C | 1 |
| Angelini, DF; Battistini, L; Berardi, A; Castelli, G; Catalano, G; Cicconi, L; D'Angiò, A; Fioritoni, G; Graziani, G; Guerrera, G; Lo-Coco, F; Massai, L; Mastrangelo, D; Noguera, NI; Pasquini, L; Pelosi, E; Piras, E; Piredda, ML; Testa, U; Voso, MT | 1 |
| Arathi, P; Binu, P; Nair, RH; Vineetha, RC | 1 |
| Chatterjee, S; Flora, SJS; Mittal, M | 1 |
| Biswas, AK; Das, S; Majumder, B | 1 |
| Li, J; Qian, G; Sun, Y; Xia, W; Xu, Y; Zhang, J | 1 |
| Abreu, MM; Carvalho, LC; Santos, ES | 1 |
| Garg, N; Kashyap, L | 1 |
| Calderon Moreno, R; Diaz, D; Escolar, E; Fonseca, V; Lamas, GA; Nathan, DM; Navas-Acien, A; Newman, J; Schmedtje, JF | 1 |
| Abreu, MM; Carvalho, LC; Magalhães, MCF; Vieira, C | 1 |
| Guo, Z; He, Y; Hu, Y; Li, Z; Peng, C; Wang, X; Xiao, X; Yan, D; Yang, A | 1 |
| Álvarez-Robles, MJ; Bernal, MP; Calderón, A; Clemente, R; Ferrer, MA | 1 |
| Imosemi, IO | 1 |
6 review(s) available for arsenic and ascorbic acid
| Article | Year |
|---|---|
Targeting the mitochondria: an exciting new approach to myeloma therapy. Commentary re: N. J. Bahlis et al., Feasibility and correlates of arsenic trioxide combined with ascorbic acid-mediated depletion of intracellular glutathione for the treatment of re
Topics: Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Clinical Trials as Topic; Drug Combinations; Glutathione; Humans; Mitochondria; Multiple Myeloma; Oxides; Reactive Oxygen Species | 2002 |
Arsenic trioxide as a treatment for myelodysplastic syndrome.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Cell Division; Clinical Trials as Topic; Dexamethasone; DNA-Binding Proteins; Drug Therapy, Combination; Glutathione; Hematologic Neoplasms; Humans; Leukemia, Promyelocytic, Acute; MDS1 and EVI1 Complex Locus Protein; Multicenter Studies as Topic; Myelodysplastic Syndromes; Neovascularization, Pathologic; Oxides; Proto-Oncogenes; Transcription Factors | 2005 |
Oxidative stress and apoptosis: a new treatment paradigm in cancer.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Buthionine Sulfoximine; Cell Death; Dose-Response Relationship, Drug; Glutathione; Hexanones; Humans; Metalloporphyrins; Models, Biological; Models, Chemical; Neoplasms; Oxidation-Reduction; Oxidative Stress; Oxides; Reactive Oxygen Species | 2006 |
Arsenic and lead induced free radical generation and their reversibility following chelation.
Topics: Acetylcysteine; Adjuvants, Pharmaceutic; Animals; Antioxidants; Arsenic; Arsenic Poisoning; Ascorbic Acid; Calcium; Chelating Agents; Free Radicals; Humans; Lead; Lead Poisoning; Melatonin; Metals; Micronutrients; Molecular Structure; Succimer; Taurine; Thioctic Acid; Unithiol; Vitamin E | 2007 |
[Selected mechanisms of the therapeutic effect of arsenic trioxide in cancer treatment].
Topics: Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Caspases; Drug Therapy, Combination; Glutathione; Humans; Intercellular Signaling Peptides and Proteins; MAP Kinase Kinase 4; Neoplasms; NF-kappa B; Oxides; Tretinoin | 2008 |
Potential Role of Metal Chelation to Prevent the Cardiovascular Complications of Diabetes.
Topics: Antioxidants; Arsenic; Ascorbic Acid; Atherosclerosis; Cadmium; Calcium Chelating Agents; Cardiovascular Diseases; Chelating Agents; Chelation Therapy; Copper; Diabetes Complications; Diabetes Mellitus; Edetic Acid; Glycation End Products, Advanced; Hospitalization; Humans; Iron; Lead; Lipid Metabolism; Mercury; Myocardial Infarction; Myocardial Revascularization; Oxidative Stress; Randomized Controlled Trials as Topic; Stroke | 2019 |
17 trial(s) available for arsenic and ascorbic acid
| Article | Year |
|---|---|
Feasibility and correlates of arsenic trioxide combined with ascorbic acid-mediated depletion of intracellular glutathione for the treatment of relapsed/refractory multiple myeloma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Drug Resistance, Neoplasm; Feasibility Studies; Female; Glutathione; Humans; Male; Middle Aged; Multiple Myeloma; Neoplasm Recurrence, Local; Oxides; Salvage Therapy; Treatment Outcome | 2002 |
Arsenic trioxide induces apoptosis of cutaneous T cell lymphoma cells: evidence for a partially caspase-independent pathway and potentiation by ascorbic acid (vitamin C).
Topics: Aged; Antineoplastic Agents; Antioxidants; Apoptosis; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Caspases; Cell Division; Cell Line, Tumor; Clone Cells; Drug Synergism; Humans; Leukocytes, Mononuclear; Lymphoma, T-Cell, Cutaneous; Middle Aged; Mitochondria; Oxides; Skin Neoplasms | 2003 |
A prospective, open-label safety and efficacy study of combination treatment with melphalan, arsenic trioxide, and ascorbic acid in patients with relapsed or refractory multiple myeloma.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Disease Progression; Drug Resistance, Neoplasm; Humans; Melphalan; Middle Aged; Multiple Myeloma; Oxides; Prospective Studies; Recurrence; Time Factors; Treatment Outcome | 2004 |
Efficacy and safety results with the combination therapy of arsenic trioxide, dexamethasone, and ascorbic acid in multiple myeloma patients: a phase 2 trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Dexamethasone; Disease-Free Survival; Female; Humans; Male; Middle Aged; Multiple Myeloma; Oxides; Recurrence; Vitamins | 2006 |
Efficacy and safety of melphalan, arsenic trioxide and ascorbic acid combination therapy in patients with relapsed or refractory multiple myeloma: a prospective, multicentre, phase II, single-arm study.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Creatinine; Female; Humans; Male; Melphalan; Middle Aged; Multiple Myeloma; Oxides; Prospective Studies; Recurrence; Survival Analysis; Treatment Outcome | 2006 |
Phase II multicenter study of arsenic trioxide, ascorbic acid and dexamethasone in patients with relapsed or refractory multiple myeloma.
Topics: Adult; Aged; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Dexamethasone; Drug Therapy, Combination; Follow-Up Studies; Humans; Middle Aged; Multiple Myeloma; Oxides; Recurrence | 2006 |
A phase I/II study of arsenic trioxide/bortezomib/ascorbic acid combination therapy for the treatment of relapsed or refractory multiple myeloma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Boronic Acids; Bortezomib; Disease-Free Survival; Female; Humans; Male; Middle Aged; Multiple Myeloma; Oxides; Pyrazines; Recurrence; Survival Analysis; Treatment Failure; Treatment Outcome | 2007 |
Arsenic trioxide/ascorbic acid therapy in patients with refractory metastatic colorectal carcinoma: a clinical experience.
Topics: Adult; Aged; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Colorectal Neoplasms; DNA Primers; Gene Expression Regulation; Humans; Middle Aged; Neoplasm Metastasis; Oxides; Thymidylate Synthase; Tomography, X-Ray Computed; Treatment Outcome | 2007 |
Phase II trial of arsenic trioxide and ascorbic acid with temozolomide in patients with metastatic melanoma with or without central nervous system metastases.
Topics: Adult; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Brain Neoplasms; Dacarbazine; Female; Humans; Male; Melanoma; Middle Aged; Oxides; Skin Neoplasms; Temozolomide | 2008 |
Phase II study of arsenic trioxide and ascorbic acid for relapsed or refractory lymphoid malignancies: a Wisconsin Oncology Network study.
Topics: Adult; Aged; Aged, 80 and over; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Female; Glutathione; Humans; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma; Lymphoma, Non-Hodgkin; Male; Middle Aged; Oxides; Safety | 2009 |
Arsenic trioxide with ascorbic acid and high-dose melphalan: results of a phase II randomized trial.
Topics: Adult; Aged; Antineoplastic Agents; Antioxidants; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Disease-Free Survival; Female; Hematopoietic Stem Cell Transplantation; Humans; Male; Melphalan; Middle Aged; Multiple Myeloma; Myeloablative Agonists; Oxides; Survival Rate; Time Factors; Transplantation Conditioning; Transplantation, Autologous | 2008 |
Combination decitabine, arsenic trioxide, and ascorbic acid for the treatment of myelodysplastic syndrome and acute myeloid leukemia: a phase I study.
Topics: Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Azacitidine; Bone Marrow; Bone Marrow Cells; Cohort Studies; Decitabine; Dose-Response Relationship, Drug; Female; Gene Expression Profiling; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Neovascularization, Pathologic; Oxides; Young Adult | 2011 |
A randomized phase 2 trial of a preparative regimen of bortezomib, high-dose melphalan, arsenic trioxide, and ascorbic acid.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Blood Transfusion, Autologous; Boronic Acids; Bortezomib; Disease-Free Survival; Drug Administration Schedule; Female; Follow-Up Studies; Hematopoietic Stem Cell Transplantation; Humans; Male; Melphalan; Middle Aged; Multiple Myeloma; Oxides; Prognosis; Pyrazines; Transplantation Conditioning | 2012 |
Oral arsenic trioxide-based maintenance regimens for first complete remission of acute promyelocytic leukemia: a 10-year follow-up study.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Cytarabine; Daunorubicin; Disease-Free Survival; Dyspepsia; Female; Follow-Up Studies; Headache; Humans; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Oxides; Recurrence; Remission Induction; Time Factors; Treatment Outcome; Tretinoin | 2011 |
A phase 2 trial of combination therapy with thalidomide, arsenic trioxide, dexamethasone, and ascorbic acid (TADA) in patients with overlap myelodysplastic/myeloproliferative neoplasms (MDS/MPN) or primary myelofibrosis (PMF).
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Dexamethasone; Disease-Free Survival; Female; Humans; Male; Myelodysplastic-Myeloproliferative Diseases; Oxides; Primary Myelofibrosis; Thalidomide | 2012 |
A Phase I study of arsenic trioxide (Trisenox), ascorbic acid, and bortezomib (Velcade) combination therapy in patients with relapsed/refractory multiple myeloma.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Boronic Acids; Bortezomib; Female; Humans; Male; Middle Aged; Multiple Myeloma; Oxides; Pyrazines; Recurrence | 2013 |
Adding ascorbic acid to arsenic trioxide produces limited benefit in patients with acute myeloid leukemia excluding acute promyelocytic leukemia.
Topics: Adult; Aged; Aged, 80 and over; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Drug Therapy, Combination; Female; Humans; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male; Middle Aged; Oxides; Treatment Outcome | 2014 |
102 other study(ies) available for arsenic and ascorbic acid
| Article | Year |
|---|---|
Variation in guinea pig responsiveness.
Topics: Age Factors; Animal Nutritional Physiological Phenomena; Animals; Arsenicals; Ascorbic Acid; Cortisone; Croton Oil; Dinitrochlorobenzene; Electric Stimulation; Female; Genes, Dominant; Guinea Pigs; Hypersensitivity, Delayed; Immunogenetics; Infections; Physical Exertion; Pregnancy; Seasons; Sex Factors; Skin Tests; Stress, Physiological | 1975 |
The influence of NAD+-linked substrates on energy conservation at sites 2 and 3 in mitochondria treated with inorganic arsenate.
Topics: Acetoacetates; Adenine Nucleotides; Animals; Arsenates; Arsenic; Ascorbic Acid; Energy Metabolism; Glutamates; Hydroxybutyrates; Mitochondria, Liver; NAD; Rats; Succinates | 1978 |
[Arsenic metabolism. (17) Studies of placental transfer of arsenic and the effects of antidotes and diet].
Topics: Animals; Antidotes; Arsenic; Ascorbic Acid; Diet; Dimercaprol; Female; Fetus; Male; Maternal-Fetal Exchange; Pregnancy; Rats; Statistics as Topic; Thioctic Acid | 1976 |
Increase in the synthesis of a Mr 32,000 protein in BALB/c 3T3 cells after treatment with tumor promoters, chemical carcinogens, metal salts, and heat shock.
Topics: 3,3'-Diaminobenzidine; Animals; Arsenic; Arsenites; Ascorbic Acid; Carcinogens; Deoxycholic Acid; Diglycerides; Diterpenes; Gene Expression Regulation; Hot Temperature; Isoelectric Point; Metals; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mice; Molecular Weight; Protease Inhibitors; Sodium Compounds; Terpenes | 1986 |
Oxidation-reduction potential-dependent adenosine triphosphatase activity of chromatophores from Rhodospirillum rubrum.
Topics: Adenosine Triphosphatases; Antimycin A; Arsenic; Ascorbic Acid; Cytoplasm; Dinitrophenols; Hydrogen-Ion Concentration; Iodine; Light; Magnesium; Oligomycins; Oxidation-Reduction; Phenazines; Phenols; Phosphorus Isotopes; Pigments, Biological; Rhodospirillum | 1968 |
Energetics of glycylglycine transport in Escherichia coli.
Topics: Adenosine Triphosphatases; Anaerobiosis; Arsenic; Ascorbic Acid; Biological Transport, Active; Calcium; Carbon Radioisotopes; Cell Membrane; Chloramphenicol; Dipeptides; Escherichia coli; Glucose; Glutamine; Glycylglycine; Lactates; Magnesium; Models, Chemical; Mutation; Osmosis; Proline; Succinates; Uncoupling Agents | 1974 |
Effect of hydroxylamine on respiration and oxidative phosphorylation.
Topics: Adenosine Triphosphatases; Aniline Compounds; Animals; Arsenic; Ascorbic Acid; Calcium; Dinitrophenols; Electron Transport Complex IV; Ferricyanides; Hydroxylamines; In Vitro Techniques; Mitochondria, Liver; Oxidative Phosphorylation; Oxidoreductases; Oxygen Consumption; Rats; Succinates; Tyrothricin | 1969 |
Respiration dependent transport of proline by electron transport particles from mycobacterium phlei.
Topics: Adenosine Triphosphate; Alcohol Oxidoreductases; Anaerobiosis; Aniline Compounds; Arsenic; Ascorbic Acid; Azides; Bacterial Proteins; Biological Transport, Active; Carbon Isotopes; Chloramphenicol; Cyanides; Electron Transport; Ethanol; Fumarates; Glucose; Inulin; Lactates; Mycobacterium; NAD; Organoids; Oxidative Phosphorylation; Oxygen Consumption; Proline; Radiation Effects; Semicarbazides; Succinates; Tritium; Ultraviolet Rays; Uncoupling Agents; Valinomycin | 1971 |
Arsenate and phosphate as modifiers of adenosine triphosphate driven energy-linked reduction. Kinetic study of the effects of modifiers on inhibition by adenosine diphosphate.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Aniline Compounds; Animals; Arsenic; Ascorbic Acid; Cattle; Electron Transport; Heart; Kinetics; Mathematics; Membranes; Mitochondria, Muscle; Myocardium; NAD; Phosphates; Succinates | 1972 |
Cofactor requirements of gamma-butyrobetaine hydroxylase from rat liver.
Topics: Aldehydes; Aminobutyrates; Animals; Arsenic; Arsenicals; Ascorbic Acid; Benzoates; Carbon Dioxide; Carbon Isotopes; Carnitine; Catalase; Chloromercuribenzoates; Chromatography, Ion Exchange; Citrates; Ethylmaleimide; Imines; Iodoacetates; Iron; Isocitrate Dehydrogenase; Ketoglutaric Acids; Kinetics; Liver; Male; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxidation-Reduction; Oxygen; Pteridines; Quinones; Rats; Succinates; Sulfhydryl Compounds; Sulfonic Acids | 1970 |
Determination of bismuth in pharmaceutical dosage forms by conventional DC polarography.
Topics: Aluminum; Arsenic; Ascorbic Acid; Bismuth; Colorimetry; Drug Combinations; Emulsions; Evaluation Studies as Topic; Glycols; Methods; Nitrates; Oxides; Polarography; Powders; Salicylates; Sodium; Suspensions; Tablets | 1972 |
Difetarsone in outpatient treatment of Trichuris trichiura infestation.
Topics: Ambulatory Care; Aniline Compounds; Antinematodal Agents; Arsenicals; Ascorbic Acid; Child; Child, Preschool; Colon; Humans; Infant; Parasite Egg Count; Radiography; South Africa; Trichuriasis | 1974 |
A study of iron transfer from rabbit transferrin to reticulocytes using synthetic chelating agents.
Topics: Acetates; Animals; Arsenic; Ascorbic Acid; Biological Transport; Bone Marrow; Bone Marrow Cells; Cell Membrane; Chelating Agents; Citrates; Deferoxamine; Dialysis; Dinitrophenols; Edetic Acid; Erythrocytes; Female; Glutathione; Hemoglobins; Imines; Iron; Iron Chelating Agents; Iron Isotopes; Kinetics; Nitriles; Phenanthrolines; Pyridines; Rabbits; Reticulocytes; Rotenone; Sulfhydryl Reagents; Temperature; Transferrin | 1971 |
Energy-dependent accumulation of calcium and phosphate by purified inner membrane vesicles of rat liver mitochondria.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Ammonia; Aniline Compounds; Animals; Arsenic; Ascorbic Acid; Biological Transport, Active; Calcium; Calcium Isotopes; Chlorides; Coloring Agents; In Vitro Techniques; Liver; Male; Membranes; Mercuribenzoates; Mitochondria, Liver; Organomercury Compounds; Oxides; Phosphates; Phosphorus Isotopes; Rats; Ruthenium; Succinates; Tritium; Uncoupling Agents | 1972 |
[Oxygraphic study of respiration in rat skeletal muscle mitochondria].
Topics: Aniline Compounds; Animals; Arsenic; Ascorbic Acid; Biological Transport; Calcium; Cyanides; Dinitrophenols; Electron Transport; Glutamates; Methods; Mitochondria, Muscle; Oligomycins; Oxidative Phosphorylation; Oxygen Consumption; Polarography; Rats; Rotenone | 1969 |
Gamma-butyrobetaine hydroxylase from Pseudomonas sp AK 1.
Topics: Amines; Arsenic; Ascorbic Acid; Benzoates; Betaine; Butyrates; Carbon Isotopes; Carnitine; Catalase; Chromatography, DEAE-Cellulose; Ethylmaleimide; Hydrogen-Ion Concentration; Hydroxyapatites; Iodoacetates; Iron; Isoelectric Focusing; Ketoglutaric Acids; Kinetics; Mercury; Metals; Mixed Function Oxygenases; Pseudomonas; Sulfhydryl Compounds | 1970 |
The dependence on dicarboxylic acids and energy of citrate accumulation in depleted rat liver mitochondria.
Topics: Adenosine Triphosphate; Aniline Compounds; Animals; Arsenic; Ascorbic Acid; Benzimidazoles; Citrates; Dicarboxylic Acids; Glutamates; Hydroxybutyrates; In Vitro Techniques; Malates; Maleates; Mitochondria, Liver; Oligomycins; Oxidation-Reduction; Potassium; Pyruvates; Rats; Rotenone; Succinates; Tartrates | 1968 |
Stoicheiometry of oxidative phosphorylation with tetramethyl-p-phenylenediamine in rat-liver mitochondria.
Topics: Aniline Compounds; Animals; Arsenic; Ascorbic Acid; Mitochondria, Liver; Mitochondria, Muscle; Myocardium; Oxidative Phosphorylation; Rats; Rotenone | 1969 |
Organization of fatty-acid activation in rat liver mitochondria.
Topics: Adenine Nucleotides; Animals; Arsenicals; Ascorbic Acid; Carnitine; Glycosides; Ligases; Liver; Mitochondria; Oligomycins; Rats | 1966 |
Enzyme-dependent ascorbate recycling in human erythrocytes: role of thioredoxin reductase.
Topics: Arsenicals; Ascorbic Acid; Aurothioglucose; Cell Membrane; Cell-Free System; Dehydroascorbic Acid; Dinitrochlorobenzene; Dose-Response Relationship, Drug; Enzymes; Erythrocytes; Ferricyanides; Glutathione; Glutathione Transferase; Hemolysis; Humans; Ketones; NADP; Thioredoxin-Disulfide Reductase; Vitamin E | 1998 |
Malignant cells can be sensitized to undergo growth inhibition and apoptosis by arsenic trioxide through modulation of the glutathione redox system.
Topics: Acetylcysteine; Animals; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Cells, Cultured; Drug Synergism; Glutathione; Growth Inhibitors; Hematopoietic Stem Cells; HL-60 Cells; Humans; Lymphoma; Mice; Mice, Inbred Strains; Oxidation-Reduction; Oxides; Tumor Cells, Cultured | 1999 |
Arsenic trioxide and ascorbic acid: synergy with potential implications for the treatment of acute myeloid leukaemia?
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antioxidants; Apoptosis; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Drug Synergism; Drug Therapy, Combination; Humans; In Situ Nick-End Labeling; Leukemia, Myeloid; Middle Aged; Oxides; Tumor Cells, Cultured | 2001 |
Protection of sodium arsenite-induced ovarian toxicity by coadministration of L-ascorbate (vitamin C) in mature wistar strain rat.
Topics: Animals; Arsenic; Ascorbic Acid; Biogenic Monoamines; Brain Chemistry; Estrus; Female; Ovary; Rats; Rats, Wistar; Water Pollutants, Chemical; Water Supply | 2001 |
Ascorbic acid enhances arsenic trioxide-induced cytotoxicity in multiple myeloma cells.
Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Cell Death; Drug Synergism; Glutathione; Humans; Hydrogen Peroxide; Multiple Myeloma; Oxides; Plasma Cells; Superoxides; Tumor Cells, Cultured | 2001 |
GSH is required to recycle ascorbic acid in cultured liver cell lines.
Topics: Animals; Arsenicals; Ascorbic Acid; Buthionine Sulfoximine; Cell Line; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutathione; Humans; Kinetics; Liver; Maleates; NADP; Rats; Thioredoxin-Disulfide Reductase; Time Factors; Water | 2001 |
In vitro and in vivo effectiveness of arsenic trioxide against murine T-cell prolymphocytic leukaemia.
Topics: Animals; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Leukemia, Prolymphocytic; Leukemia, T-Cell; Male; Mice; Mice, Transgenic; Models, Animal; Oxides; Proto-Oncogene Proteins; Survival Rate; Tumor Cells, Cultured | 2002 |
[Ascorbic acid enhances the apoptosis of U937 cells induced by arsenic trioxide in combination with DMNQ and its mechanism].
Topics: Apoptosis; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Drug Synergism; Flow Cytometry; Humans; Naphthoquinones; Oxides; U937 Cells | 2002 |
Activation of Rac1 and the p38 mitogen-activated protein kinase pathway in response to arsenic trioxide.
Topics: Antioxidants; Apoptosis; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Bone Marrow Cells; Enzyme Activation; Enzyme Inhibitors; Growth Inhibitors; Humans; Imidazoles; Isoenzymes; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Oxides; p38 Mitogen-Activated Protein Kinases; Pyridines; rac1 GTP-Binding Protein; Tumor Cells, Cultured | 2002 |
Clinical activity of arsenic trioxide in Burkitt-like lymphoma.
Topics: Acute Disease; Adult; Antigens, CD; Antineoplastic Agents; Antioxidants; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Burkitt Lymphoma; Drug Therapy, Combination; Female; Humans; L-Lactate Dehydrogenase; Leukemia, Lymphoid; Oxides; Salvage Therapy; Treatment Outcome | 2003 |
Ascorbic acid and alpha-tocopherol as potent modulators on arsenic induced toxicity in mitochondria.
Topics: alpha-Tocopherol; Antioxidants; Arsenic; Ascorbic Acid; Electron Transport Complex IV; Isocitrate Dehydrogenase; Ketoglutarate Dehydrogenase Complex; Kidney; Lipid Peroxidation; Mitochondria; Mitochondria, Liver; NADH Dehydrogenase; Succinate Dehydrogenase | 2003 |
ITCHING PURPURA.
Topics: Arsenic; Ascorbic Acid; Diagnosis, Differential; Drug Therapy; Eczema; Egypt; Hemosiderosis; Histamine H1 Antagonists; Humans; Pathology; Pruritus; Purpura | 1963 |
ACTIVATION AND INACTIVATION OF P-HYDROXYPHENYLPYRUVATE HYDROXYLASE.
Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Animals; Arsenicals; Ascorbic Acid; Chelating Agents; Chromates; Copper; Dialysis; Enzyme Inhibitors; Ferrocyanides; Glutathione; Guinea Pigs; Hydrogen Peroxide; Indophenol; Iron; Liver; Mercury; Mixed Function Oxygenases; Nickel; Phenanthrolines; Phenylpyruvic Acids; Pyrroles; Rats; Renal Dialysis; Research; Tin; Zinc | 1964 |
THE ACTION OF DIO-9: AN INHIBITOR AND AN UNCOUPLER OF OXIDATIVE PHOSPHORYLATION.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Anti-Bacterial Agents; Antimetabolites; Arsenic; Ascorbic Acid; Dinitrophenols; Enzyme Repression; Glutamates; Hydroxybutyrates; Ketoglutaric Acids; Liver; Metabolism; Mitochondria; Organic Chemicals; Oxidative Phosphorylation; Pharmacology; Phosphates; Rats; Research; Succinates | 1964 |
POSSIBLE PARTIAL REACTIONS OF THE PHOTOPHOSPHORYLATION PROCESS IN CHROMATOPHORES FROM RHODOSPIRILLUM RUBRUM.
Topics: Adenine Nucleotides; Adenosine Triphosphatases; Adenosine Triphosphate; Arsenicals; Ascorbic Acid; Chromatophores; Dinitrophenols; Diphosphates; Oxidative Phosphorylation; Pharmacology; Phenanthrolines; Phenazines; Photophosphorylation; Photosynthesis; Quinacrine; Quinine; Research; Rhodospirillum; Rhodospirillum rubrum | 1965 |
THE EFFECT OF SOME SUBSTRATES AND METABOLIC INHIBITORS ACTING ON THE RESPIRATORY CHAIN ON ACID SECRETION AND OXYGEN UPTAKE BY GASTRIC MUCOSA OF THE FROG.
Topics: Amobarbital; Aniline Compounds; Animals; Anura; Arsenicals; Ascorbic Acid; Biological Transport; Bodily Secretions; Dinitrophenols; Electron Transport; Gastric Acidity Determination; Gastric Mucosa; Metabolism; Mitochondrial Membranes; Molybdenum; Oxygen; Pharmacology; Physiology; Pyruvates; Research; Silicon Dioxide; Vitamin K | 1965 |
Reduction and uptake of methylene blue by human erythrocytes.
Topics: Arsenicals; Ascorbic Acid; Cell Membrane; Dose-Response Relationship, Drug; Erythrocytes; Extracellular Fluid; Ferricyanides; Glutathione; Humans; Methylene Blue; NADH, NADPH Oxidoreductases; NADP; Oxidation-Reduction; Oxidative Stress; Subcellular Fractions | 2004 |
Chronic arsenic poisoning in the rat: treatment with combined administration of succimers and an antioxidant.
Topics: Animals; Antioxidants; Arsenic; Arsenic Poisoning; Ascorbic Acid; Brain Chemistry; Chelating Agents; Drug Interactions; Drug Therapy, Combination; Heme; Male; Oxidative Stress; Rats; Rats, Wistar; Succimer; Tissue Distribution | 2004 |
L-ascorbic acid represses constitutive activation of NF-kappaB and COX-2 expression in human acute myeloid leukemia, HL-60.
Topics: Apoptosis; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Cyclooxygenase 2; DNA; Down-Regulation; Electrophoretic Mobility Shift Assay; Glutathione; HL-60 Cells; Humans; Hydrogen Peroxide; Isoenzymes; Leukemia, Myeloid, Acute; Membrane Proteins; NF-kappa B; Oxides; Prostaglandin-Endoperoxide Synthases; Protein Subunits; Superoxides; Tosylphenylalanyl Chloromethyl Ketone; Transcription Factor RelA | 2004 |
Efficacy of melphalan, arsenic trioxide, and ascorbic acid combination therapy (MAC) in relapsed and refractory multiple myeloma.
Topics: Aged; Antineoplastic Agents, Alkylating; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Female; Humans; Male; Melphalan; Middle Aged; Multiple Myeloma; Oxides; Recurrence; Treatment Outcome | 2005 |
Vitamin C protects HL60 and U266 cells from arsenic toxicity.
Topics: Arsenic; Ascorbic Acid; Biological Transport; Cell Line, Tumor; Cell-Free System; Glutathione; HL-60 Cells; Humans; Hydrogen Peroxide; Oxidation-Reduction; Reactive Oxygen Species | 2005 |
Effect of cysteine, methionine, ascorbic acid and thiamine on arsenic-induced oxidative stress and biochemical alterations in rats.
Topics: Alanine Transaminase; Animals; Antioxidants; Arsenic; Ascorbic Acid; Aspartate Aminotransferases; Blood Proteins; Body Weight; Creatinine; Cysteine; Erythrocytes; Kidney; Lipid Peroxides; Liver; Male; Malondialdehyde; Methionine; Oxidative Stress; Rats; Rats, Wistar; Thiamine; Urea | 2005 |
Effect of experimentally induced reducing conditions on the mobility of arsenic from a mining soil.
Topics: Arsenic; Ascorbic Acid; Borohydrides; Hazardous Waste; Hydrogen-Ion Concentration; Kinetics; Mining; Oxidation-Reduction; Soil Pollutants | 2005 |
Role of the alkali labile sites, reactive oxygen species and antioxidants in DNA damage induced by methylated trivalent metabolites of inorganic arsenic.
Topics: Adult; Alkalies; Antioxidants; Arsenic; Arsenicals; Ascorbic Acid; Cacodylic Acid; Cell Survival; Cells, Cultured; DNA; DNA Damage; Dose-Response Relationship, Drug; Humans; Lymphocytes; Methylation; Oxidation-Reduction; Reactive Oxygen Species; Reference Values; Selenomethionine | 2005 |
Ascorbic acid differentially modulates the induction of heme oxygenase-1, NAD(P)H:quinone oxidoreductase 1 and glutathione S-transferase Ya by As(3+), Cd(2+) and Cr(6+).
Topics: Animals; Antioxidants; Arsenicals; Ascorbic Acid; Biological Transport; Blotting, Northern; Cadmium Compounds; Cell Line, Tumor; Chromium Compounds; Cytochrome P-450 CYP1A1; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glutathione Transferase; Heme Oxygenase-1; NAD(P)H Dehydrogenase (Quinone); Organometallic Compounds; Polychlorinated Dibenzodioxins; RNA, Messenger | 2007 |
Enhanced recovery of arsenite sorbed onto synthetic oxides by L-ascorbic acid addition to phosphate solution: calibrating a sequential leaching method for the speciation analysis of arsenic in natural samples.
Topics: Adsorption; Anaerobiosis; Arsenic; Ascorbic Acid; Calibration; Ferric Compounds; Hydrogen-Ion Concentration; Iron Compounds; Manganese Compounds; Minerals; Phosphates; Water Pollutants, Chemical; Water Purification | 2006 |
Role of oxidative stress in the apoptosis of hepatocellular carcinoma induced by combination of arsenic trioxide and ascorbic acid.
Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; Apoptosis; Arsenic Trioxide; Arsenicals; Ascorbic Acid; bcl-2-Associated X Protein; Carcinoma, Hepatocellular; Cell Line, Tumor; Drug Synergism; Free Radical Scavengers; Humans; Liver Neoplasms; Oxidative Stress; Oxides; Proto-Oncogene Proteins c-bcl-2 | 2006 |
The effect of intracellular ascorbate on the susceptibility of HL60 and Jurkat cells to chemotherapy agents.
Topics: Antineoplastic Agents; Antioxidants; Apoptosis; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Caspases; Cell Count; Dehydroascorbic Acid; Drug Resistance, Neoplasm; Etoposide; HL-60 Cells; Humans; Jurkat Cells; Melphalan; Oxides | 2006 |
Arsenic-induced toxicity and the protective role of ascorbic acid in mouse testis.
Topics: Animals; Antioxidants; Arsenic; Ascorbic Acid; Biomarkers; Glutathione; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Organ Size; Reproduction; Reverse Transcriptase Polymerase Chain Reaction; Sperm Count; Sperm Motility; Testicular Diseases; Testis; Testosterone | 2007 |
Protective effect of ascorbic acid against oxidative stress induced by inorganic arsenic in liver and kidney of rat.
Topics: Animals; Antioxidants; Arsenic; Ascorbic Acid; Female; Kidney; Liver; Male; Oxidative Stress; Rats; Rats, Wistar | 2007 |
Antimyeloma effects of arsenic trioxide are enhanced by melphalan, bortezomib and ascorbic acid.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Boronic Acids; Bortezomib; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Enzyme-Linked Immunosorbent Assay; Humans; Immunoglobulin G; Melphalan; Mice; Mice, SCID; Multiple Myeloma; Oxides; Pyrazines; Xenograft Model Antitumor Assays | 2007 |
Arsenic metabolism in multiple myeloma and astrocytoma cells.
Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Astrocytoma; Biotransformation; Bone Marrow Cells; Cell Line, Tumor; Chromatography, Ion Exchange; Humans; Models, Chemical; Multiple Myeloma; Oxides; Reactive Oxygen Species; Time Factors | 2007 |
Amelioration of arsenic toxicity by L-Ascorbic acid in laboratory rat.
Topics: Alanine Transaminase; Animals; Antioxidants; Arsenic; Arsenic Poisoning; Ascorbic Acid; Aspartate Aminotransferases; Bilirubin; DNA Damage; Glutathione; Glutathione Disulfide; Glutathione Transferase; Kidney; Lipid Peroxidation; Liver; Male; Rats; Rats, Wistar | 2007 |
Mitochondrial recycling of ascorbic acid as a mechanism for regenerating cellular ascorbate.
Topics: alpha-Tocopherol; Animals; Arsenicals; Ascorbic Acid; Carmustine; Dehydroascorbic Acid; Diamide; Ethylmaleimide; Ferricyanides; Guinea Pigs; In Vitro Techniques; Maleates; Mitochondria, Muscle; Oxidation-Reduction; Sulfhydryl Reagents | 2007 |
[Effects of vitamin C combined with arsenic trioxide on the apoptosis of Hep-2 cell].
Topics: Apoptosis; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Cell Line, Tumor; Drug Synergism; Humans; Oxides | 2008 |
Flow injection-hydride generation atomic absorption spectrometric determination of selenium, arsenic and bismuth.
Topics: Arsenic; Ascorbic Acid; Bismuth; Catalysis; Chemistry Techniques, Analytical; Edetic Acid; Equipment Design; Metals; Oxygen; Potassium Iodide; Selenium; Spectrophotometry, Atomic; Temperature; Water | 2008 |
Protective effects of B vitamins and antioxidants on the risk of arsenic-related skin lesions in Bangladesh.
Topics: Adult; Antioxidants; Arsenic; Ascorbic Acid; Bangladesh; Cross-Sectional Studies; Environmental Exposure; Female; Humans; Male; Middle Aged; Precancerous Conditions; Risk Factors; Skin Diseases; Vitamin A; Vitamin B Complex; Vitamin E | 2008 |
Ascorbic acid combats arsenic-induced oxidative stress in mice liver.
Topics: Animals; Antioxidants; Arsenic; Arsenic Poisoning; Ascorbic Acid; Biomarkers; Enzyme Activation; Liver; Mice; Micronucleus Tests; Microscopy, Electron; Oxidative Stress | 2009 |
In vitro model improves the prediction of soil arsenic bioavailability: worst-case scenario.
Topics: Animals; Arsenic; Ascorbic Acid; Biological Availability; Cholecalciferol; Dehydroepiandrosterone; Ecosystem; Environmental Exposure; Gastric Acid; Hydrogen-Ion Concentration; Mice; Mice, Inbred BALB C; Models, Biological; Nicotinic Acids; Oryza; Plant Extracts; Reproducibility of Results; Soil Pollutants | 2008 |
Protective action of vitamins C and P against dichlorophenarsine hydrochloride.
Topics: Anti-Infective Agents; Arsenic; Arsenicals; Ascorbic Acid; Vitamins | 1948 |
Gamma-glutamyltransferase-dependent resistance to arsenic trioxide in melanoma cells and cellular sensitization by ascorbic acid.
Topics: Apoptosis; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Catalase; Cell Line, Tumor; Cytoprotection; Drug Resistance, Neoplasm; Enzyme Activation; gamma-Glutamyltransferase; Gene Expression Regulation, Neoplastic; Growth Inhibitors; Humans; MAP Kinase Kinase Kinase 5; Melanoma; Oxidative Stress; Oxides | 2009 |
Subchronic exposure to arsenic decreased Sdha expression in the brain of mice.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antioxidants; Arsenic Trioxide; Arsenicals; Ascorbic Acid; ATP Synthetase Complexes; Brain; Computational Biology; Cytochromes c; Deoxyguanosine; Dose-Response Relationship, Drug; Electron Transport; Electron Transport Chain Complex Proteins; Electron Transport Complex III; Electron Transport Complex IV; Gene Expression Profiling; Gene Expression Regulation; Growth Inhibitors; Mice; Oligonucleotide Array Sequence Analysis; Oxides; Succinate Dehydrogenase; Taurine | 2009 |
Arsenic-induced oxidative cerebral disorders: protection by taurine.
Topics: Acetylcholinesterase; Adenosine Triphosphatases; Amino Acids, Essential; Animals; Antioxidants; Apoptosis; Arsenic; Arsenic Poisoning; Ascorbic Acid; Brain; Catalase; Disease Models, Animal; Dose-Response Relationship, Drug; Free Radical Scavengers; Glutathione; Glutathione Transferase; Lipid Peroxidation; Male; Oxidants; Oxidative Stress; Rats; Reactive Oxygen Species; Sulfhydryl Compounds; Taurine | 2009 |
Evaluation of adverse cardiac effects induced by arsenic trioxide, a potent anti-APL drug.
Topics: Action Potentials; Animals; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Dose-Response Relationship, Drug; Drug Antagonism; Edema, Cardiac; Guinea Pigs; Heart; Leukemia, Promyelocytic, Acute; Male; Membrane Transport Modulators; Myocardium; Oxidants; Oxides; Oxidoreductases; Vasodilator Agents | 2009 |
Arsenic trioxide and ascorbic acid demonstrate promising activity against primary human CLL cells in vitro.
Topics: Amino Acid Chloromethyl Ketones; Amitrole; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Arsenic Trioxide; Arsenicals; Ascorbic Acid; B-Lymphocytes; Buthionine Sulfoximine; Catalase; Cell Line, Tumor; Cysteine Proteases; Cysteine Proteinase Inhibitors; Drug Evaluation, Preclinical; Drug Synergism; Enzyme Activation; Glutathione; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Neoplasm Proteins; Oxidants; Oxidative Stress; Oxides; Reactive Oxygen Species | 2010 |
Supplementation of ascorbic acid prevents oxidative damages in arsenic-loaded hepatic tissue of rat: an ex vivo study.
Topics: Animals; Antioxidants; Arsenic; Ascorbic Acid; Catalase; Environmental Pollutants; Lipid Peroxidation; Liver; Male; Nitric Oxide; Organ Culture Techniques; Oxidative Stress; Protein Carbonylation; Rats; Rats, Wistar; Superoxide Dismutase; Time Factors; Toxicity Tests | 2010 |
Ascorbic acid improves mitochondrial function in liver of arsenic-treated rat.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Animals; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Caspase 3; Dose-Response Relationship, Drug; Histocytochemistry; Liver; Male; Mitochondria, Liver; Oxidative Phosphorylation; Oxides; Rats; Rats, Wistar; Succinate Dehydrogenase | 2010 |
Vitamin C quantification in syphilitic patients under arsenical treatment.
Topics: Arsenic; Ascorbic Acid; Syphilis | 1946 |
Arsenic release from flooded paddy soils is influenced by speciation, Eh, pH, and iron dissolution.
Topics: Arsenic; Ascorbic Acid; Hydrogen-Ion Concentration; Iron; Oxidation-Reduction; Soil; Soil Pollutants; Water Pollutants, Chemical | 2011 |
Differential augmentative effects of buthionine sulfoximine and ascorbic acid in As2O3-induced ovarian cancer cell death: oxidative stress-independent and -dependent cytotoxic potentiation.
Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Buthionine Sulfoximine; Cell Death; Cell Line, Tumor; Drug Synergism; Female; Fibroblasts; Glutathione; Glutathione Peroxidase; Humans; Intracellular Space; Ovarian Neoplasms; Oxidative Stress; Oxides | 2011 |
As(2)O (3) oxidation by vitamin C: cell culture studies.
Topics: Animals; Antineoplastic Agents; Antioxidants; Arsenic Trioxide; Arsenicals; Arsenites; Ascorbic Acid; Cattle; Cell Culture Techniques; Cell Line, Tumor; Culture Media; Oxidation-Reduction; Oxides | 2012 |
Metabolic adaptation of Pteris vittata L. gametophyte to arsenic induced oxidative stress.
Topics: Arsenic; Ascorbic Acid; Biomass; Glutathione; Lipid Peroxidation; Oxidative Stress; Pteris; Quality Control | 2011 |
Effects of inorganic and organic arsenic compounds on growth and apoptosis of human T-lymphoblastoid leukemia cells.
Topics: Acetylcysteine; Apoptosis; Arsenic; Ascorbic Acid; Benzimidazoles; Buthionine Sulfoximine; Caspase 3; Caspase 7; Cell Line, Tumor; Cell Proliferation; Female; Humans; Inhibitory Concentration 50; Leukemia, T-Cell; Leukocytes, Mononuclear; Models, Chemical; Organic Chemicals; T-Lymphocytes; Tetrazolium Salts; Thiazoles | 2011 |
Superparamagnetic high-surface-area Fe3O4 nanoparticles as adsorbents for arsenic removal.
Topics: Adsorption; Arsenic; Ascorbic Acid; Ferric Compounds; Metal Nanoparticles; Microscopy, Electron, Transmission; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction | 2012 |
Arsenic trioxide induces human pulmonary fibroblast cell death via increasing ROS levels and GSH depletion.
Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; Apoptosis; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Buthionine Sulfoximine; Cell Death; Cell Line, Tumor; Fibroblasts; Glutathione; Humans; Lung; Oxides; Reactive Oxygen Species; Transfection | 2012 |
Arsenic trioxide and ascorbic acid interfere with the BCL2 family genes in patients with myelodysplastic syndromes: an ex-vivo study.
Topics: Aged; Apoptosis; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Female; Gene Expression; Genes, bcl-2; Humans; Male; Myelodysplastic Syndromes; Oxides; Real-Time Polymerase Chain Reaction | 2012 |
Toxic effects of perinatal arsenic exposure on the brain of developing rats and the beneficial role of natural antioxidants.
Topics: Acetylcholinesterase; Acid Phosphatase; Alkaline Phosphatase; Animals; Animals, Newborn; Antioxidants; Arsenic; Ascorbic Acid; Brain; Catalase; Female; Glutathione; Lactation; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Vitamin E; Zinc | 2013 |
Nitric oxide alleviates arsenic-induced toxic effects in ridged Luffa seedlings.
Topics: Arsenic; Ascorbic Acid; Catalase; Hydrogen Peroxide; Lipid Peroxidation; Luffa; Malondialdehyde; Nitric Oxide; Nitroprusside; Oxidative Stress; Photosynthesis; Seedlings | 2013 |
The effect of coadministration of α-tocopherol and ascorbic acid on arsenic trioxide-induced testicular toxicity in adult rats.
Topics: alpha-Tocopherol; Animals; Antioxidants; Arsenic Trioxide; Arsenicals; Ascorbic Acid; DNA Damage; Drug Synergism; Drug Therapy, Combination; Endocrine Disruptors; Male; Oxidative Stress; Oxides; Rats; Rats, Wistar; Spermatogenesis; Testis; Testosterone | 2013 |
Ameliorative effect of diallyl trisulphide on arsenic-induced oxidative stress in rat erythrocytes and DNA damage in lymphocytes.
Topics: Allyl Compounds; Animals; Antioxidants; Arsenic; Ascorbic Acid; DNA Damage; Erythrocyte Membrane; Erythrocytes; Garlic; Lipid Peroxides; Lymphocytes; Male; Nitric Oxide; Oxidative Stress; Rats, Wistar; Sulfides | 2014 |
Redirecting apoptosis to aponecrosis induces selective cytotoxicity to pancreatic cancer cells through increased ROS, decline in ATP levels, and VDAC.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Cell Line, Tumor; Disease Models, Animal; Disulfiram; Dose-Response Relationship, Drug; Heterografts; Humans; Male; Mice; Necrosis; Oxides; Pancreatic Neoplasms; Reactive Oxygen Species; Tumor Stem Cell Assay; Voltage-Dependent Anion Channels | 2013 |
Determination of Cu, As, Hg and Pb in vegetable oils by electrothermal vaporization inductively coupled plasma mass spectrometry with palladium nanoparticles as modifier.
Topics: Arsenic; Ascorbic Acid; Copper; Emulsions; Humans; Indicator Dilution Techniques; Isotopes; Lead; Limit of Detection; Mercury; Metal Nanoparticles; Octoxynol; Palladium; Plant Oils; Spectrophotometry, Atomic; Volatilization | 2013 |
Differential modulation of xenobiotic-metabolizing enzymes in rats following single and concurrent exposure to chlorpyrifos, arsenic, and ascorbic acid.
Topics: Animals; Antioxidants; Arsenic; Ascorbic Acid; Chlorpyrifos; Drinking Water; Insecticides; Male; Microsomes, Liver; Rats; Rats, Wistar; Toxicity Tests, Subacute; Water Pollutants, Chemical | 2013 |
Acute toxicity of arsenic to Aliivibrio fischeri (Microtox bioassay) as influenced by potential competitive-protective agents.
Topics: Aliivibrio fischeri; Arsenic; Ascorbic Acid; Biological Assay; Citric Acid; Drug Interactions; Glycerol; Organic Chemicals; Phosphates; Protective Agents; Toxicity Tests, Acute | 2014 |
Green tea and vitamin C ameliorate some neuro-functional and biochemical signs of arsenic toxicity in rats.
Topics: Animals; Antioxidants; Arsenic; Arsenic Poisoning; Ascorbic Acid; Brain; Dietary Supplements; Evoked Potentials; Food Handling; Lipid Peroxidation; Male; Neural Conduction; Neurons; Neuroprotective Agents; Oxidative Stress; Rats, Wistar; Tea; Toxicokinetics; Water Pollutants, Chemical; Weight Gain | 2016 |
Abiotic reductive extraction of arsenic from contaminated soils enhanced by complexation: arsenic extraction by reducing agents and combination of reducing and chelating agents.
Topics: Adsorption; Arsenic; Ascorbic Acid; Chelating Agents; Dithionite; Ferric Compounds; Oxalates; Oxides; Reducing Agents; Soil; Soil Pollutants | 2015 |
Synergistic effects of arsenic trioxide combined with ascorbic acid in human osteosarcoma MG-63 cells: a systems biology analysis.
Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Bone Neoplasms; Cell Line, Tumor; Drug Synergism; Drug Therapy, Combination; Humans; Osteosarcoma; Oxides; Systems Biology | 2014 |
Alterations in antioxidant defense system of workers chronically exposed to arsenic, cadmium and mercury from coal flying ash.
Topics: Adult; Air Pollutants; Antioxidants; Arsenic; Ascorbic Acid; Cadmium; Coal Ash; Glutathione Peroxidase; Humans; Kosovo; Male; Mercury; Middle Aged; Occupational Exposure; Oxidative Stress; Power Plants; Superoxide Dismutase | 2016 |
Protection against arsenic-induced hematological and hepatic anomalies by supplementation of vitamin C and vitamin E in adult male rats.
Topics: Age Factors; Animals; Arsenic; Ascorbic Acid; Dietary Supplements; Erythrocytes; Liver; Male; Protective Agents; Random Allocation; Rats; Rats, Wistar; Vitamin E | 2016 |
Synergistic effects of the combination of oxalate and ascorbate on arsenic extraction from contaminated soils.
Topics: Adsorption; Arsenic; Ascorbic Acid; Chelating Agents; Environmental Pollution; Environmental Restoration and Remediation; Ferric Compounds; Iron; Models, Chemical; Oxalates; Soil; Soil Pollutants | 2017 |
Arsenic affects the production of glucosinolate, thiol and phytochemical compounds: A comparison of two Brassica cultivars.
Topics: Arsenic; Ascorbic Acid; Brassica; Glucosinolates; Phenols; Phenotype; Phytochemicals; Plant Leaves; Plant Proteins; Plant Roots; Plant Shoots; Seedlings; Sulfhydryl Compounds; Sulfur | 2017 |
Arsenic-induced stress activates sulfur metabolism in different organs of garlic (Allium sativum L.) plants accompanied by a general decline of the NADPH-generating systems in roots.
Topics: Antioxidants; Arsenic; Ascorbic Acid; Garlic; Glutathione; Lipid Peroxidation; NADP; Organ Specificity; Oxidative Stress; Oxidoreductases; Phenotype; Phytochelatins; Plant Roots; Plant Shoots; Stress, Physiological; Sulfur | 2017 |
High-dose ascorbate and arsenic trioxide selectively kill acute myeloid leukemia and acute promyelocytic leukemia blasts in vitro.
Topics: Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Oxides; Reactive Oxygen Species; Survival Analysis; Tumor Cells, Cultured | 2017 |
L-ascorbic acid and α-tocopherol attenuate arsenic trioxide-induced toxicity in H9c2 cardiomyocytes by the activation of Nrf2 and Bcl2 transcription factors.
Topics: alpha-Tocopherol; Animals; Antioxidants; Apoptosis; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Cardiotoxicity; Cell Line; Cytoprotection; Heart Diseases; Membrane Potential, Mitochondrial; Mitochondria, Heart; Myocytes, Cardiac; NF-E2-Related Factor 2; Oxidative Stress; Oxides; Proto-Oncogene Proteins c-bcl-2; Rats; Signal Transduction | 2018 |
Combination therapy with vitamin C and DMSA for arsenic-fluoride co-exposure in rats.
Topics: Animals; Arsenic; Ascorbic Acid; Catalase; CD13 Antigens; DNA Damage; Fluorides; Glucosephosphate Dehydrogenase; Glutamyl Aminopeptidase; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Male; Oxidative Stress; Porphobilinogen Synthase; Rats; Rats, Wistar; Reactive Oxygen Species; Succimer; Superoxide Dismutase | 2018 |
Modulation of growth, ascorbate-glutathione cycle and thiol metabolism in rice (Oryza sativa L. cv. MTU-1010) seedlings by arsenic and silicon.
Topics: Antioxidants; Arsenate Reductases; Arsenic; Ascorbate Peroxidases; Ascorbic Acid; Glutathione; Glutathione Peroxidase; Oryza; Phytochelatins; Plant Roots; Seedlings; Silicon; Soil Pollutants; Sulfhydryl Compounds | 2018 |
Enhanced remediation of arsenic and chromium co-contaminated soil by eletrokinetic-permeable reactive barriers with different reagents.
Topics: Adsorption; Arsenic; Ascorbic Acid; Chelating Agents; Chromium; Edetic Acid; Environmental Restoration and Remediation; Ferric Compounds; Sodium Citrate; Soil; Soil Pollutants; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction | 2019 |
Unraveling the crucial role of the ascorbate-glutathione cycle in the resilience of Cistus monspeliensis L. to withstand high As concentrations.
Topics: Anthocyanins; Arsenic; Ascorbic Acid; Cistus; Glutathione; Hydrogen Peroxide; Hydrogen-Ion Concentration; Limit of Detection; Mining; Oxidative Stress; Plant Development; Plant Leaves; Plant Roots | 2019 |
Joint effects of Si and mycorrhiza on the antioxidant metabolism of two pigeonpea genotypes under As (III) and (V) stress.
Topics: Antioxidants; Arsenates; Arsenic; Arsenites; Ascorbic Acid; Biomass; Cajanus; Genotype; Glomeromycota; Glutathione; Mycorrhizae; Plant Development; Plant Roots; Silicon; Soil Pollutants; Symbiosis; Vanadium | 2019 |
Physiological response of Cistus salviifolius L. to high arsenic concentrations.
Topics: Antioxidants; Arsenic; Ascorbic Acid; Biodegradation, Environmental; Chlorophyll; Cistus; Environmental Pollutants; Glutathione; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydroponics; Oxidative Stress; Plant Roots | 2020 |
Cleanup of arsenic, cadmium, and lead in the soil from a smelting site using N,N-bis(carboxymethyl)-L-glutamic acid combined with ascorbic acid: A lab-scale experiment.
Topics: Arsenic; Ascorbic Acid; Cadmium; Ferric Compounds; Glutamic Acid; Lead; Metals, Heavy; Soil; Soil Pollutants | 2021 |
Effects of ascorbic acid addition on the oxidative stress response of Oryza sativa L. plants to As(V) exposure.
Topics: Antioxidants; Arsenic; Ascorbic Acid; Oryza; Oxidative Stress; Plant Roots; Seedlings | 2022 |
Aquoeus Extracts of Daucus Carota (Linn) Protected the Postnatal Developing Cerebellum of Wistar Rats Against Arsenic-Induced Oxidative Stress.
Topics: Animals; Antioxidants; Arsenic; Ascorbic Acid; Catalase; Cerebellum; Daucus carota; Female; Lipid Peroxidation; Neuroprotective Agents; Oxidative Stress; Pregnancy; Rats; Rats, Wistar; Superoxide Dismutase | 2021 |