Page last updated: 2024-09-02

aristolochic acid ii and aristolochic acid i

aristolochic acid ii has been researched along with aristolochic acid i in 44 studies

Compound Research Comparison

Studies
(aristolochic acid ii)
Trials
(aristolochic acid ii)
Recent Studies (post-2010)
(aristolochic acid ii)
Studies
(aristolochic acid i)
Trials
(aristolochic acid i)
Recent Studies (post-2010) (aristolochic acid i)
500171,0882548

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-19907 (15.91)18.7374
1990's3 (6.82)18.2507
2000's15 (34.09)29.6817
2010's18 (40.91)24.3611
2020's1 (2.27)2.80

Authors

AuthorsStudies
Borges, S; Chan, TM; Fischmann, T; Gullo, VP; Hegde, VR; Kirschmeier, P; Madison, V; Patel, M; Pu, H; Williams, MJ; Wu, B1
Pfau, W; Schmeiser, HH; Wiessler, M1
Schmeiser, HH; Schoepe, KB; Wiessler, M1
Pool, BL; Schmeiser, HH; Wiessler, M2
Krumbiegel, G; Roth, HJ1
Hallensleben, J; Krumbiegel, G; Mennicke, WH; Rittmann, N; Roth, HJ1
Chu, Y; Deng, WL; Guo, ZW; Li, RX; Li, ZH; Pan, DB; Wang, WL1
Maier, P; Schawalder, HP; Weibel, B; Zbinden, G1
Mengs, U; Stotzem, CD1
Götzl, E; Schimmer, O1
Arlt, VM; Schmeiser, HH; Wiessler, M1
Applequist, WL; Khan, IA; Schaneberg, BT1
Cunningham, G; Goun, E; Krasnykch, O; Miles, H; Solodnikov, S1
Fan, C; Li, G; Liu, L; Sun, Z; Wang, Q; Zheng, X1
Che, B; Feng, X; Gong, S; Hu, S; Li, W; Liao, Y; Liu, H; Wen, D1
Chen, Z; Li, W; Liao, Y; Liu, H1
Bonala, RR; Dong, H; Grollman, AP; Johnson, F; Shibutani, S; Suzuki, N; Torres, MC1
Chan, K; Cheung, TP; Leung, K; Li, CG; Xue, C1
Dong, H; Grollman, AP; Miller, F; Shibutani, S; Suzuki, N; Ueda, S1
Cai, SQ; Li, XM; Qu, L; Wang, X; Xu, JY; Zhao, DH1
Feng, YQ; Wei, F1
Chen, XJ; Fang, F; Lu, Q; Wang, GJ1
Cai, Z; Fu, X; Li, W; Liu, H; Liu, Y; Nie, H; Pang, N1
Chan, J; Heinrich, M; Neinhuis, C; Simmonds, MS; Wanke, S1
Kawaguchi, M; Okihashi, M; Sakagami, Y; Satake, M; Sekita, S; Tagami, T; Takatori, S; Yamasaki, K1
Attaluri, S; Bonala, RR; Grollman, AP; Iden, CR; Johnson, F; Lukin, MA; Moriya, M; Wen, Y; Yang, IY1
Kang, JJ; Kuo, CH; Lee, CW; Lee, SS; Lin, SC; Peng, FC; Tsai, IL; Tseng, YJ; Wei-Chu, L1
Chen, CX1
Bai, Y; Fu, X; Li, W; Liao, Y; Liu, H; Liu, Y1
Arlt, VM; Frei, E; Hudecek, J; Kubickova, B; Martinek, V; Schmeiser, HH; Stiborova, M1
Chen, M; Gong, L; Luan, Y; Nohmi, T; Qi, X; Ren, J; Wu, Y; Xing, G; Yao, J1
Feng, Q; Han, S; Liu, Y; Wang, J1
Krynitsky, AJ; Rader, JI; Vaclavik, L1
Pu, FP; Song, RJ; Sun, JB; Zeng, P; Zhang, Q; Zhou, J1
Kirubakaran, SA; Pradeepa, V; Sathish-Narayanan, S; Senthil-Nathan, S; Thanigaivel, A1
Chan, W; Hu, Q; Li, W1
Bottai, C; Boucaud-Maitre, D; Cachet, X; Dufat, H; Langrand, J; Locatelli-Jouans, C; Nossin, E1
Abu Zarga, MH; Al-Barham, MB; Al-Jaber, HI; Al-Qudah, MA1
Colet, JM; De Prez, E; Declèves, AE; Duquesne, M; Nortier, J1
Cotoras, M; Melo, R; Mendoza, L; Sanhueza, L1
Chang, C; Fu, Q; Ge, YH; Guo, PQ; Liu, RL; Luo, ZM; Shu, H; Xu, XY1
Cai, Z; Guo, W; He, Y; Lin, Z; Luo, K; Sun, Q1
Dong, H; Duan, W; Li, Y; Wang, W; Wang, X; Yang, G1

Reviews

1 review(s) available for aristolochic acid ii and aristolochic acid i

ArticleYear
Local uses of Aristolochia species and content of nephrotoxic aristolochic acid 1 and 2--a global assessment based on bibliographic sources.
    Journal of ethnopharmacology, 2009, Aug-17, Volume: 125, Issue:1

    Topics: Animals; Aristolochia; Aristolochic Acids; Humans; Kidney; Species Specificity

2009

Other Studies

43 other study(ies) available for aristolochic acid ii and aristolochic acid i

ArticleYear
Semi-synthetic aristolactams--inhibitors of CDK2 enzyme.
    Bioorganic & medicinal chemistry letters, 2010, Feb-15, Volume: 20, Issue:4

    Topics: Aristolochic Acids; CDC2 Protein Kinase; Cell Line, Tumor; Computer Simulation; Crystallography, X-Ray; Humans; Inhibitory Concentration 50; Models, Molecular; Molecular Structure; Pyrazoles; Quinolines; Structure-Activity Relationship

2010
32P-postlabelling analysis of the DNA adducts formed by aristolochic acid I and II.
    Carcinogenesis, 1990, Volume: 11, Issue:9

    Topics: Animals; Aristolochic Acids; Autoradiography; Carcinogens; Chromatography, High Pressure Liquid; DNA; Male; Phenanthrenes; Phosphorus Radioisotopes; Rats; Rats, Inbred Strains; Tissue Distribution; Xanthine Oxidase

1990
DNA adduct formation of aristolochic acid I and II in vitro and in vivo.
    Carcinogenesis, 1988, Volume: 9, Issue:2

    Topics: Animals; Aristolochic Acids; Carcinogens; DNA; In Vitro Techniques; Male; Phenanthrenes; Rats; Rats, Inbred Strains; Tissue Distribution

1988
Identification and mutagenicity of metabolites of aristolochic acid formed by rat liver.
    Carcinogenesis, 1986, Volume: 7, Issue:1

    Topics: Animals; Aristolochic Acids; Kinetics; Magnetic Resonance Spectroscopy; Microsomes, Liver; Mutagenicity Tests; Mutagens; Mutation; Phenanthrenes; Rats; Salmonella typhimurium; Spectrophotometry

1986
[Partial synthesis of aristolochic acid I and II derivatives as reference materials for metabolite production in the rat].
    Archiv der Pharmazie, 1987, Volume: 320, Issue:3

    Topics: Animals; Aristolochic Acids; Biotransformation; Magnetic Resonance Spectroscopy; Phenanthrenes; Rats

1987
Studies on the metabolism of aristolochic acids I and II.
    Xenobiotica; the fate of foreign compounds in biological systems, 1987, Volume: 17, Issue:8

    Topics: Animals; Aristolochic Acids; Biotransformation; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Feces; Guinea Pigs; Male; Mutagens; Phenanthrenes; Rabbits; Rats; Rats, Inbred Strains; Species Specificity

1987
[Stepwise discriminant analysis on the relationship of immunostimulative activities and chemical structure of substituted cinnamic acids].
    Sichuan yi xue yuan xue bao = Acta Academiae Medicinae Sichuan, 1985, Volume: 16, Issue:3

    Topics: Animals; Antineoplastic Agents; Aristolochic Acids; Bayes Theorem; Cinnamates; Immunity, Cellular; Macrophage Activation; Mice; Phagocytosis; Phenanthrenes; Structure-Activity Relationship

1985
Aristolochic acid induces 6-thioguanine-resistant mutants in an extrahepatic tissue in rats after oral application.
    Mutation research, 1985, Volume: 143, Issue:3

    Topics: Administration, Oral; Animals; Aristolochic Acids; Drug Resistance; Granuloma; Hypoxanthine Phosphoribosyltransferase; Inactivation, Metabolic; Male; Methylnitronitrosoguanidine; Mutagenicity Tests; Mutagens; Phenanthrenes; Rats; Rats, Inbred Strains; Thioguanine

1985
Mutagenicity of the two main components of commercially available carcinogenic aristolochic acid in Salmonella typhimurium.
    Cancer letters, 1984, Volume: 23, Issue:1

    Topics: Aristolochic Acids; Mutagenicity Tests; Mutagens; Nitroreductases; Oxidoreductases; Phenanthrenes; Salmonella typhimurium

1984
Renal toxicity of aristolochic acid in rats as an example of nephrotoxicity testing in routine toxicology.
    Archives of toxicology, 1993, Volume: 67, Issue:5

    Topics: Animals; Aristolochic Acids; Body Weight; Carcinogens; Creatinine; Dose-Response Relationship, Drug; Female; Kidney; Kidney Diseases; Kidney Function Tests; Organ Size; Phenanthrenes; Rats; Rats, Wistar; Urea

1993
Mutagenicity of aristolochic acids (I, II) and aristolic acid I in new YG strains in Salmonella typhimurium highly sensitive to certain mutagenic nitroarenes.
    Mutagenesis, 1993, Volume: 8, Issue:1

    Topics: Aristolochic Acids; DNA Damage; Mutagenicity Tests; Phenanthrenes; Plant Extracts; Plasmids; Salmonella typhimurium; Structure-Activity Relationship

1993
Using polymerase arrest to detect DNA binding specificity of aristolochic acid in the mouse H-ras gene.
    Carcinogenesis, 2000, Volume: 21, Issue:2

    Topics: Adenine; Animals; Aristolochic Acids; Base Composition; Carcinogens; Codon; Deoxyadenosines; Deoxyguanosine; DNA Adducts; DNA Damage; DNA Replication; DNA-Directed DNA Polymerase; DNA, Recombinant; Genes, ras; Guanine; Mice; Oligodeoxyribonucleotides; Phenanthrenes; Plasmids; Templates, Genetic

2000
Determination of aristolochic acid I and II in North American species of Asarum and Aristolochia.
    Die Pharmazie, 2002, Volume: 57, Issue:10

    Topics: Aristolochia; Aristolochic Acids; Asarum; Calibration; Chromatography, High Pressure Liquid; North America; Reference Standards

2002
Antithrombin activity of some constituents from Origanum vulgare.
    Fitoterapia, 2002, Volume: 73, Issue:7-8

    Topics: Antineoplastic Agents; Antithrombins; Aristolochic Acids; Leukemia; Molecular Structure; Origanum; Raffinose; Triterpenes; Ursolic Acid

2002
An easy and rapid method to determine aristolochic acids I and II with high sensitivity.
    Analytical and bioanalytical chemistry, 2004, Volume: 378, Issue:2

    Topics: Aristolochia; Aristolochic Acids; Chromatography, High Pressure Liquid; Electrochemistry; Electrodes; Molecular Structure; Sensitivity and Specificity; Stephania tetrandra

2004
Rapid determination of aristolochic acid I and II in Aristolochia plants from different regions by beta-cyclodextrin-modified capillary zone electrophoresis.
    Journal of chromatography. A, 2004, Sep-17, Volume: 1049, Issue:1-2

    Topics: Algorithms; Aristolochia; Aristolochic Acids; beta-Cyclodextrins; Buffers; Calibration; Chromatography, High Pressure Liquid; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Indicators and Reagents; Isomerism; Reference Standards; Reproducibility of Results; Solvents; Spectrophotometry, Ultraviolet; Temperature

2004
Study on separation of aristolochic acid I and II by micellar electrokinetic capillary chromatography and competition mechanism between SDS and beta-cyclodextrin.
    Electrophoresis, 2006, Volume: 27, Issue:4

    Topics: Antiviral Agents; Aristolochia; Aristolochic Acids; beta-Cyclodextrins; Chromatography, Micellar Electrokinetic Capillary; Sodium Dodecyl Sulfate

2006
Quantitative determination of aristolochic acid-derived DNA adducts in rats using 32P-postlabeling/polyacrylamide gel electrophoresis analysis.
    Drug metabolism and disposition: the biological fate of chemicals, 2006, Volume: 34, Issue:7

    Topics: Animals; Aristolochic Acids; Biomarkers; DNA; DNA Adducts; Electrophoresis, Polyacrylamide Gel; Intestinal Mucosa; Intestines; Kidney; Liver; Male; Mutagens; Oligonucleotides; Phosphorus Radioisotopes; Rats; Rats, Wistar; Reproducibility of Results

2006
Aristolochic acids detected in some raw Chinese medicinal herbs and manufactured herbal products--a consequence of inappropriate nomenclature and imprecise labelling?
    Clinical toxicology (Philadelphia, Pa.), 2006, Volume: 44, Issue:4

    Topics: Aristolochic Acids; Drug Labeling; Drugs, Chinese Herbal; Plants, Medicinal; Terminology as Topic

2006
Selective toxicity of aristolochic acids I and II.
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:7

    Topics: Animals; Aristolochic Acids; Carcinogens; Cell Transformation, Neoplastic; DNA Adducts; Fibrosis; Kidney Cortex; Kidney Diseases; Kidney Medulla; Male; Mice; Mice, Inbred C3H; Mutagens; Plant Preparations; Urinary Bladder

2007
[Studies on solid phase extraction method of aristolochic acids and aristololactams in rat urine].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2007, Volume: 32, Issue:24

    Topics: Administration, Oral; Animals; Aristolochia; Aristolochic Acids; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Male; Random Allocation; Rats; Rats, Wistar; Solid Phase Extraction

2007
Rapid determination of aristolochic acid I and II in medicinal plants with high sensitivity by cucurbit[7]uril-modifier capillary zone electrophoresis.
    Talanta, 2008, Jan-15, Volume: 74, Issue:4

    Topics: Aristolochic Acids; Bridged-Ring Compounds; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Imidazoles; Plants, Medicinal; Sensitivity and Specificity

2008
[Study of pharmacokinetics of aristolochic acid I and II in rats].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2008, Volume: 33, Issue:19

    Topics: Animals; Aristolochic Acids; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Male; Rats; Rats, Sprague-Dawley; Reproducibility of Results

2008
Analysis of aristolochic acids by CE-MS with carboxymethyl chitosan-coated capillary.
    Electrophoresis, 2009, Volume: 30, Issue:10

    Topics: Aristolochic Acids; Chitosan; Electrophoresis, Capillary; Humans; Mass Spectrometry; Sensitivity and Specificity

2009
Simple and rapid analysis of aristolochic acid contained in crude drugs and Kampo formulations with solid-phase extraction and HPLC photodiode-array detection.
    Journal of natural medicines, 2009, Volume: 63, Issue:4

    Topics: Aristolochic Acids; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Medicine, Kampo; Solid Phase Extraction

2009
DNA adducts of aristolochic acid II: total synthesis and site-specific mutagenesis studies in mammalian cells.
    Nucleic acids research, 2010, Volume: 38, Issue:1

    Topics: Animals; Aristolochic Acids; Cells, Cultured; DNA; DNA Adducts; Mice; Mutagenesis; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides

2010
Rapid determination of aristolochic acids I and II in herbal products and biological samples by ultra-high-pressure liquid chromatography-tandem mass spectrometry.
    Talanta, 2010, Mar-15, Volume: 80, Issue:5

    Topics: Animals; Aristolochia; Aristolochic Acids; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Female; Limit of Detection; Male; Mice; Rats; Rats, Wistar; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2010
[Studies on the chemical constituents from the fruit of Aristolochia debilis].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2010, Volume: 33, Issue:8

    Topics: Aristolochia; Aristolochic Acids; Fruit; Indole Alkaloids; Lactams; Molecular Structure

2010
Determination of dissociation constants of aristolochic acid I and II by capillary electrophoresis with carboxymethyl chitosan-coated capillary.
    Talanta, 2011, Jul-15, Volume: 85, Issue:1

    Topics: Aristolochic Acids; Chitosan; Electrophoresis, Capillary; Toxicology

2011
Comparison of activation of aristolochic acid I and II with NADPH:quinone oxidoreductase, sulphotransferases and N-acetyltranferases.
    Neuro endocrinology letters, 2011, Volume: 32 Suppl 1

    Topics: Acetyltransferases; Animals; Aristolochic Acids; Biotransformation; Catalytic Domain; Cells, Cultured; DNA Adducts; Enzyme Activation; Humans; Lactams; Models, Molecular; Molecular Conformation; NAD(P)H Dehydrogenase (Quinone); Protein Binding; Sulfotransferases

2011
Comparison of the mutagenicity of aristolochic acid I and aristolochic acid II in the gpt delta transgenic mouse kidney.
    Mutation research, 2012, Mar-18, Volume: 743, Issue:1-2

    Topics: Animals; Aristolochic Acids; Carcinogens; DNA Adducts; DNA Damage; Escherichia coli Proteins; Kidney; Mice; Mice, Transgenic; Mutagens; Pentosyltransferases

2012
[Determination of aristolochic acids A and B in Chinese herbals and traditional Chinese patent medicines using ultra high performance liquid chromatography-triple quadrupole mass spectrometry].
    Se pu = Chinese journal of chromatography, 2011, Volume: 29, Issue:11

    Topics: Aristolochic Acids; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2011
Quantification of aristolochic acids I and II in herbal dietary supplements by ultra-high-performance liquid chromatography-multistage fragmentation mass spectrometry.
    Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 2014, Volume: 31, Issue:5

    Topics: Analytic Sample Preparation Methods; Aristolochic Acids; Carcinogens; Chromatography, High Pressure Liquid; Dietary Supplements; Drug Contamination; Drugs, Chinese Herbal; Food Contamination; Food Inspection; Internet; Limit of Detection; Plant Extracts; Plant Preparations; Poisons; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; United States

2014
Three-phase hollow fiber liquid-phase microextraction based on a magnetofluid for the analysis of aristolochic acids in plasma by high-performance liquid chromatography.
    Journal of separation science, 2014, Volume: 37, Issue:13

    Topics: Animals; Aristolochic Acids; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Limit of Detection; Liquid Phase Microextraction; Male; Rats; Rats, Sprague-Dawley

2014
Toxicity of aristolochic acids isolated from Aristolochia indica Linn (Aristolochiaceae) against the malarial vector Anopheles stephensi Liston (Diptera: Culicidae).
    Experimental parasitology, 2015, Volume: 153

    Topics: Aedes; Animals; Aristolochia; Aristolochic Acids; Humans; Insect Vectors; Insecticides; Larva; Malaria; Plant Extracts

2015
Mass Spectrometric and Spectrofluorometric Studies of the Interaction of Aristolochic Acids with Proteins.
    Scientific reports, 2015, Oct-16, Volume: 5

    Topics: Animals; Aristolochic Acids; Cattle; Muramidase; Protein Binding; Serum Albumin, Bovine; Spectrometry, Fluorescence; Spectrometry, Mass, Electrospray Ionization

2015
Detection of aristolochic acids I and II in "Chiniy-trèf", a traditional medicinal preparation containing caterpillars feeding on Aristolochia trilobata L. in Martinique, French West Indies.
    Toxicon : official journal of the International Society on Toxinology, 2016, Volume: 114

    Topics: Animals; Aristolochia; Aristolochic Acids; Butterflies; Feeding Behavior; Larva; Martinique; Medicine, Traditional; Toxins, Biological

2016
New aristolochic acid and other chemical constituents of Aristolochia maurorum growing wild in Jordan.
    Natural product research, 2017, Volume: 31, Issue:3

    Topics: Amides; Anti-Infective Agents; Aristolochia; Aristolochic Acids; Coumaric Acids; Glucosides; Jordan; Propionates; Tyramine

2017
Interest of metabonomic approach in environmental nephrotoxicants: Application to aristolochic acid exposure.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2017, Volume: 108, Issue:Pt A

    Topics: Animals; Aristolochic Acids; Environmental Pollutants; Kidney Diseases; Male; Metabolomics; Pilot Projects; Random Allocation; Rats

2017
Characterization of the fungitoxic activity on Botrytis cinerea of the aristolochic acids I and II.
    Letters in applied microbiology, 2019, Volume: 68, Issue:1

    Topics: Antifungal Agents; Aristolochic Acids; Botrytis; Cell Membrane; DNA, Fungal; Mycelium; Spores, Fungal

2019
Combined magnetic porous molecularly imprinted polymers and deep eutectic solvents for efficient and selective extraction of aristolochic acid I and II from rat urine.
    Materials science & engineering. C, Materials for biological applications, 2019, Volume: 97

    Topics: Animals; Aristolochic Acids; Choline; Chromatography, High Pressure Liquid; Glycols; Magnetics; Molecular Imprinting; Polymers; Porosity; Rats; Solid Phase Extraction; Solvents; Spectrophotometry, Ultraviolet

2019
Poly-l-lysine-based tissue embedding compatible with matrix-assisted laser desorption ionization-mass spectrometry imaging analysis of dry and fragile aristolochia plants.
    Journal of chromatography. A, 2019, Dec-20, Volume: 1608

    Topics: Aristolochia; Aristolochic Acids; Gelatin; Polylysine; Specimen Handling; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tissue Embedding

2019
Isolation and purification of six aristolochic acids with similar structures from Aristolochia manshuriensis Kom stems by pH-zone-refining counter-current chromatography.
    Journal of chromatography. A, 2020, Feb-22, Volume: 1613

    Topics: Aristolochia; Aristolochic Acids; Countercurrent Distribution; Hydrogen-Ion Concentration; Plant Extracts; Plant Stems; Solvents

2020