aristolochic acid i and aristolactam i

aristolochic acid i has been researched along with aristolactam i in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (7.14)18.2507
2000's4 (28.57)29.6817
2010's6 (42.86)24.3611
2020's3 (21.43)2.80

Authors

AuthorsStudies
Borges, S; Chan, TM; Fischmann, T; Gullo, VP; Hegde, VR; Kirschmeier, P; Madison, V; Patel, M; Pu, H; Williams, MJ; Wu, B1
Bieler, CA; Breuer, A; Frei, E; Schmeiser, HH; Stiborová, M1
Cai, SQ; Li, B; Li, XM; Wang, X; Zhang, CY2
Bonala, RR; Dong, H; Grollman, AP; Johnson, F; Shibutani, S; Suzuki, N; Torres, MC1
Cai, SQ; Li, XM; Qu, L; Wang, X; Xu, JY; Zhao, DH1
Chen, CX1
Heinrich, M; Kite, GC; Michl, J; Neinhuis, C; Simmonds, MS; Vollmer, G; Wanke, S; Zierau, O1
Attaluri, S; Bonala, R; Grollman, AP; Hashimoto, K; Iden, CR; Johnson, F; Moriya, M; Ozga, K; Sidorenko, VS; Zaitseva, IN1
Bonala, R; Grollman, AP; Hashimoto, K; Johnson, F; Moriya, M1
Abu Zarga, MH; Al-Barham, MB; Al-Jaber, HI; Al-Qudah, MA1
Han, J; Li, C; Liang, A; Liu, C; Liu, M; Liu, S; Meng, J; Pan, C; Qin, S; Tang, X; Tian, J; Wang, F; Wang, L; Wang, Y; Yi, Y; Zhang, Y; Zhao, Y1
Au, CK; Chan, W; Ham, YH1
Chiang, SY; Chimeddulam, D; Hsu, PC; Huang, HF; Luo, YS; Shih, WC; Tsai, TH; Wey, MT; Wu, KY1

Other Studies

14 other study(ies) available for aristolochic acid i and aristolactam i

ArticleYear
Semi-synthetic aristolactams--inhibitors of CDK2 enzyme.
    Bioorganic & medicinal chemistry letters, 2010, Feb-15, Volume: 20, Issue:4

    Topics: Aristolochic Acids; CDC2 Protein Kinase; Cell Line, Tumor; Computer Simulation; Crystallography, X-Ray; Humans; Inhibitory Concentration 50; Models, Molecular; Molecular Structure; Pyrazoles; Quinolines; Structure-Activity Relationship

2010
Aristolactam I a metabolite of aristolochic acid I upon activation forms an adduct found in DNA of patients with Chinese herbs nephropathy.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 1999, Volume: 51, Issue:4-5

    Topics: Animals; Aristolochic Acids; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Dioxoles; DNA; DNA Adducts; Drugs, Chinese Herbal; Fibrosis; Horseradish Peroxidase; Humans; Hydrogen Peroxide; Indoles; Kidney Diseases; Male; Phenanthrenes; Rats; Rats, Sprague-Dawley; Ureter

1999
[Cellular mechanism of renal proximal tubular epithelial cell injury induced by aristolochic acid I and aristololactam I].
    Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2004, Volume: 36, Issue:1

    Topics: Apoptosis; Aristolochic Acids; Cell Line; Epithelial Cells; Fibronectins; Humans; Kidney Tubules, Proximal; Transforming Growth Factor beta; Transforming Growth Factor beta1

2004
[Injury in renal proximal tubular epithelial cells induced by aristololactam I].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2004, Volume: 29, Issue:1

    Topics: Apoptosis; Aristolochia; Aristolochic Acids; Cell Line; Cell Membrane; Diploidy; DNA; Dose-Response Relationship, Drug; Epithelial Cells; Humans; Kidney Tubules, Proximal; Plants, Medicinal

2004
Quantitative determination of aristolochic acid-derived DNA adducts in rats using 32P-postlabeling/polyacrylamide gel electrophoresis analysis.
    Drug metabolism and disposition: the biological fate of chemicals, 2006, Volume: 34, Issue:7

    Topics: Animals; Aristolochic Acids; Biomarkers; DNA; DNA Adducts; Electrophoresis, Polyacrylamide Gel; Intestinal Mucosa; Intestines; Kidney; Liver; Male; Mutagens; Oligonucleotides; Phosphorus Radioisotopes; Rats; Rats, Wistar; Reproducibility of Results

2006
[Studies on solid phase extraction method of aristolochic acids and aristololactams in rat urine].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2007, Volume: 32, Issue:24

    Topics: Administration, Oral; Animals; Aristolochia; Aristolochic Acids; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Male; Random Allocation; Rats; Rats, Wistar; Solid Phase Extraction

2007
[Studies on the chemical constituents from the fruit of Aristolochia debilis].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2010, Volume: 33, Issue:8

    Topics: Aristolochia; Aristolochic Acids; Fruit; Indole Alkaloids; Lactams; Molecular Structure

2010
LC-MS- and (1)H NMR-Based Metabolomic Analysis and in Vitro Toxicological Assessment of 43 Aristolochia Species.
    Journal of natural products, 2016, Jan-22, Volume: 79, Issue:1

    Topics: Aristolochia; Aristolochic Acids; Chromatography, Liquid; Drugs, Chinese Herbal; Humans; Kidney Diseases; Metabolomics; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plants, Medicinal

2016
Sulfotransferase-1A1-dependent bioactivation of aristolochic acid I and N-hydroxyaristolactam I in human cells.
    Carcinogenesis, 2016, Volume: 37, Issue:7

    Topics: Aristolochic Acids; Arylsulfotransferase; Carcinogens; DNA; Fibroblasts; Gene Knockdown Techniques; Humans; Kidney; Multienzyme Complexes; NADPH-Ferrihemoprotein Reductase; Pentachlorophenol; RNA, Small Interfering; Sulfate Adenylyltransferase; Xanthine Dehydrogenase

2016
Y-family DNA polymerase-independent gap-filling translesion synthesis across aristolochic acid-derived adenine adducts in mouse cells.
    DNA repair, 2016, Volume: 46

    Topics: Animals; Aristolochic Acids; Base Sequence; Carcinogens; DNA Adducts; DNA Polymerase iota; DNA-Directed DNA Polymerase; Fibroblasts; Gene Knockout Techniques; Humans; Mice; Nucleotidyltransferases; Plasmids

2016
New aristolochic acid and other chemical constituents of Aristolochia maurorum growing wild in Jordan.
    Natural product research, 2017, Volume: 31, Issue:3

    Topics: Amides; Anti-Infective Agents; Aristolochia; Aristolochic Acids; Coumaric Acids; Glucosides; Jordan; Propionates; Tyramine

2017
Long-term oral administration of Asarum heterotropoides f. mandshuricum (Maxim.) Kitag. decoction and its aristolochic acid analogs do not cause renal toxicity in mice.
    Journal of ethnopharmacology, 2023, May-10, Volume: 307

    Topics: Animals; Aristolochic Acids; Asarum; COVID-19; Humans; Kidney; Mice

2023
Bioaccumulation and DNA Adduct Formation of Aristolactam I: Unmasking a Toxicological Mechanism in the Pathophysiology of Aristolochic Acid Nephropathy.
    Chemical research in toxicology, 2023, 02-20, Volume: 36, Issue:2

    Topics: Aristolochic Acids; Bioaccumulation; Carcinogens; DNA Adducts; Humans; Kidney Diseases; Neoplasms

2023
Simultaneous toxicokinetic studies of aristolochic acid I and II and aristolactam I and II using a newly-developed microdialysis liquid chromatography-tandem mass spectrometry.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2023, Volume: 177

    Topics: Animals; Aristolochic Acids; Balkan Nephropathy; Chromatography, Liquid; Kidney Diseases; Microdialysis; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry; Toxicokinetics

2023