Page last updated: 2024-08-24

aristeromycin and adenosine

aristeromycin has been researched along with adenosine in 65 studies

Research

Studies (65)

Timeframe	Studies, this research(%)	All Research%
pre-1990	18 (27.69)	18.7374
1990's	15 (23.08)	18.2507
2000's	19 (29.23)	29.6817
2010's	13 (20.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Brownell, J; Daluge, S; Vince, R	1
Cristalli, G; Esker, JL; Jacobson, KA; Ji, XD; Melman, N; Olah, ME; Schneller, SW; Secrist, JA; Siddiqi, SM; Tiwari, KN	1
Jacobson, KA; Ji, X; Li, AH; Marquez, VE; Melman, N; Ravi, RG; Shin, KJ; Siddiqui, MA	1
Bartlett, WJ; Borchardt, RT; Borcherding, DR; Lee, Y; Wolfe, MS	1
Cools, M; de Clercq, E	1
Chaffee, S; Greenberg, ML; Hershfield, MS	1
Boehme, R; Madhavan, GV; Martin, JC; McGee, DP; Prisbe, EJ; Rydzewski, RM	1
Allan, PW; Bennett, LL; Brockman, RW; Clayton, JD; Rose, LM; Shaddix, SC; Shealy, YF	1
Imai, J; Lesiak, K; Sawai, H; Torrence, PF	1
Dunham, EW; Vince, R	1
Allan, PW; Bennett, LL; Bowdon, BJ; Rose, LM	1
Clayton, SJ; Montgomery, JA; O'Dell, CA; Secrist, JA; Shealy, YF	1
De Clercq, E	1
Allan, PW; Bennett, LL; Comber, RN; Rose, LM; Secrist, JA	1
Hiraoka, O; Iguchi, S; Matsuda, A; Satake, H; Ueda, T; Wataya, Y	1
Ohno, M	1
Kasahara, F; Kusaka, T; Marumoto, R; Miyashita, O	1
Balzarini, J; De Clercq, E; Herdewijn, P; Vanderhaeghe, H	1
Adachi, K; Arita, M; Ohno, M; Sawai, H	1
Chiang, PK; Guranowski, A; Segall, JE	1
Imoto, M; Kawada, M; Masuoka, S; Mizutani, Y; Umezawa, K	1
Hattori, H; Matsuda, A; Nonomura, M; Shuto, S; Yoshimura, Y	1
Ault-Riché, DB; Borchardt, RT; Borcherding, DR; Hasobe, M; Lee, Y; Wolfe, MS; Yuan, CS	1
Bailey, VC; Fortt, SM; Galione, A; Potter, BV; Summerhill, RJ	1
De Clercq, E; González, M; Jashés, M; López-Lastra, M; Sandino, A	1
Bacchi, CJ; Rattendi, D; Schneller, SW; Seley, KL	1
Schneller, SW; Seley, KL; Wu, J	1
Umezawa, K	1
Fujiwara, T; Saito, I; Sugiyama, H	1
Andrei, G; Balzarini, J; Borges, JE; De Clercq, E; Fernández, F; García, X; Hergueta, AR; López, C; Snoeck, R; Witvrounw, M	1
Balzarini, J; De Clercq, E; Ghosh, A; Miller, MJ	1
Abel, CB; Lindon, JC; Nicholson, JK; Noble, D; Rudd, BA; Sidebottom, PJ	1
Dancer, JE; Dudfield, PJ; Earnshaw, CG; Hewitt, BD; Lindell, SD; Moloney, BA	1
Brown, B; Hegedus, LS	1
Jacobson, KA; Ji, XD; Lee, K; Marquez, VE; Ravi, G	1
Choi, WJ; Chun, MW; Jeong, LS; Jung, YH; Kim, HO; Moon, HR; Park, JG; Yoo, SJ	1
Gurjar, MK; Maheshwar, K	1
Wnuk, SF	1
Heimberger, M; Pierik, AJ; Rétey, J; Weigl, U	1
Schneller, SW; Tuncbilek, M	1
Kitade, Y; Kojima, H; Kozaki, A; Nakanishi, M; Ueno, Y; Yamaguchi, T	1
CANTONI, GL; JAMIESON, GA; MUDD, SH	1
Ainai, T; Kobayashi, Y; Tokoro, Y; Wang, YG	1
Schneller, SW; Yang, M; Ye, W	1
Collins, SD; Danhof, M; de Boer, AG; Dejongh, J; Ijzerman, AP; Schaddelee, MP	1
Ito, Y; Kitade, Y; Nakamura, KT; Nakanishi, M; Tanaka, N; Yabe, S	1
Roy, A; Schneller, SW; Serbessa, T	1
Schneller, SW; Ye, W	1
Li, W; Schneller, SW; Yin, X	1
Ando, T; Iwata, M; Kitade, Y; Miyamoto, T; Nakanishi, M; Zulfiqar, F	1
Ando, T; Iwata, M; Kitade, Y; Kojima, H; Kozaki, A	1
Ando, T; Kitade, Y; Kojima, H; Nakanishi, M; Zulfiqar, F	1
Gowen, BB; Jung, KH; Larson, D; Morrey, JD; Schneller, SW; Sefing, EJ; Skirpstunas, R; Smee, DF; Wong, MH; Ye, W	1
Benson, S; Dornbush, PJ; Land, KM; Rapp, M; Shokar, A; Vazquez-Anaya, G; Wnuk, SF; Wrischnik, LA	1
Kaib, PS; Osipov, M; Sorum, MT; Trost, BM	1
Nian, S; Tan, X; Wang, G; Wang, P	1
Chu, J; Hu, X; Zhang, S; Zhuang, Y	1
Gouda, H; Ishihara, M; Kitade, Y; Kuroda, D; Kusakabe, Y; Nakamura, KT; Nakanishi, M; Tanaka, N; Umeda, T	1
Bariwal, J; Rawal, RK; Singh, V	1
Baba, M; Bal, C; Jha, AK; Kasula, M; Rozy, F; Samunuri, R; Sharon, A; Toyama, M; Yadav, M	1
Eguchi, T; Kudo, F; Takashima, M; Tsunoda, T	1
Kawamoto, T; Tanaka, Y; Uchiyama, N	1
Cai, YS; Chen, W; Deng, Z; Gao, Y; Gong, R; Hong, K; Hu, Y; Jiang, M; Kong, L; Liu, P; Price, NPJ; Xu, G; Xu, L	1
Bal, C; Jha, AK; Samunuri, R	1
Eguchi, T; Kudo, F; Miyanaga, A; Tsunoda, T; Yamaguchi, K	1

Reviews

3 review(s) available for aristeromycin and adenosine

Article	Year
S-adenosylhomocysteine hydrolase inhibitors as broad-spectrum antiviral agents. Biochemical pharmacology, 1987, Aug-15, Volume: 36, Issue:16 Topics: Adenosine; Adenosylhomocysteinase; Animals; Antiviral Agents; Hydrolases; Models, Biological; Tubercidin; Virus Replication	1987
Targeting "hydrolytic" activity of the S-adenosyl-L-homocysteine hydrolase. Mini reviews in medicinal chemistry, 2001, Volume: 1, Issue:3 Topics: Adenosine; Adenosylhomocysteinase; Coronary Disease; Drug Design; Enzyme Inhibitors; Homocysteine; Humans; Hydrolases; Hydrolysis; Risk Factors; Structure-Activity Relationship	2001
Chemistry and Bioactivities of Aristeromycins: An Overview. Current topics in medicinal chemistry, 2016, Volume: 16, Issue:28 Topics: Adenosine; Humans	2016

Other Studies

62 other study(ies) available for aristeromycin and adenosine

Article	Year
Carbocyclic analogues of xylofuranosylpurine nucleosides. Synthesis and antitumor activity. Journal of medicinal chemistry, 1984, Volume: 27, Issue:10 Topics: Adenosine Deaminase; Animals; Antibiotics, Antineoplastic; Chemical Phenomena; Chemistry; Leukemia P388; Magnetic Resonance Spectroscopy; Mice; Purine Nucleosides; Spectrophotometry, Infrared; Structure-Activity Relationship	1984
Search for new purine- and ribose-modified adenosine analogues as selective agonists and antagonists at adenosine receptors. Journal of medicinal chemistry, 1995, Mar-31, Volume: 38, Issue:7 Topics: Adenosine; Animals; Cell Membrane; CHO Cells; Corpus Striatum; Cricetinae; In Vitro Techniques; Magnetic Resonance Spectroscopy; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Radioligand Assay; Rats; Recombinant Proteins; Ribose; Structure-Activity Relationship	1995
Methanocarba analogues of purine nucleosides as potent and selective adenosine receptor agonists. Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11 Topics: Animals; Cell Membrane; CHO Cells; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Purine Nucleosides; Purinergic P1 Receptor Agonists; Radioligand Assay; Rats; Sulfur Radioisotopes	2000
4'-modified analogues of aristeromycin and neplanocin A: synthesis and inhibitory activity toward S-adenosyl-L-homocysteine hydrolase. Journal of medicinal chemistry, 1992, May-15, Volume: 35, Issue:10 Topics: Adenosine; Adenosylhomocysteinase; Animals; Cattle; Hydrolases; Liver; Phosphorylation	1992
Correlation between the antiviral activity of acyclic and carbocyclic adenosine analogues in murine L929 cells and their inhibitory effect on L929 cells S-adenosylhomocysteine hydrolase. Biochemical pharmacology, 1989, Apr-01, Volume: 38, Issue:7 Topics: Adenine; Adenosine; Adenosylhomocysteinase; Animals; Antiviral Agents; Cell Line; Fibroblasts; Hydrolases; Kinetics; Mice; Vaccinia virus; Vesicular stomatitis Indiana virus; Virus Replication	1989
Basis for resistance to 3-deazaaristeromycin, an inhibitor of S-adenosylhomocysteine hydrolase, in human B-lymphoblasts. The Journal of biological chemistry, 1989, Jan-15, Volume: 264, Issue:2 Topics: Adenosine; Adenosylhomocysteinase; B-Lymphocytes; Cell Line; Clone Cells; Drug Resistance; Enzyme Inhibitors; Humans; Hydrolases; Isomerism; Kinetics; Tubercidin	1989
Synthesis and antiviral evaluation of 6'-substituted aristeromycins: potential mechanism-based inhibitors of S-adenosylhomocysteine hydrolase. Journal of medicinal chemistry, 1988, Volume: 31, Issue:9 Topics: Adenosine; Adenosylhomocysteinase; Animals; Antiviral Agents; Chemical Phenomena; Chemistry; Hydrolases; Rabbits; Simplexvirus; Structure-Activity Relationship; Vaccinia virus; Virus Replication	1988
Inhibition of utilization of hypoxanthine and guanine in cells treated with the carbocyclic analog of adenosine. Phosphates of carbocyclic nucleoside analogs as inhibitors of hypoxanthine (guanine) phosphoribosyltransferase. Molecular pharmacology, 1985, Volume: 27, Issue:6 Topics: Adenosine; Animals; Carcinoma, Squamous Cell; Cell Line; Coformycin; Colonic Neoplasms; Cyclic GMP; Cyclic IMP; Guanine; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Inosine Nucleotides; Kinetics; Leukemia L1210; Mice; Pentosyltransferases; Ribonucleotides	1985
Replacement of the ribofuranose oxygen of 2-5A derivatives by methylene: synthesis of an aristeromycin analogue of 2-5A core 5'-monophosphate (5'-O-phosphoryladenylyl)(2'----5')adenyl(2'----5')adenosine. Journal of medicinal chemistry, 1985, Volume: 28, Issue:9 Topics: Adenine Nucleotides; Adenosine; Animals; Cell Line; Chemical Phenomena; Chemistry; Endonucleases; Endoribonucleases; Enzyme Activation; Half-Life; Humans; L Cells; Lymphocytes; Mice; Oligoribonucleotides; Rabbits; Reticulocytes	1985
Hypotensive and renal vasodilator effects of carbocyclic adenosine (aristeromycin) in anesthetized spontaneously hypertensive rats. The Journal of pharmacology and experimental therapeutics, 1986, Volume: 238, Issue:3 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Aminophylline; Anesthesia; Animals; Antihypertensive Agents; Blood Pressure; Male; Rats; Rats, Inbred SHR; Receptors, Cell Surface; Receptors, Purinergic; Renal Circulation; Vasodilator Agents	1986
Evidence that the carbocyclic analog of adenosine has different mechanisms of cytotoxicity to cells with adenosine kinase activity and to cells lacking this enzyme. Biochemical pharmacology, 1986, Nov-15, Volume: 35, Issue:22 Topics: Adenosine; Adenosine Kinase; Adenosylhomocysteinase; Cell Survival; Cells, Cultured; Hydrolases; Phosphotransferases	1986
Resolution of racemic carbocyclic analogues of purine nucleosides through the action of adenosine deaminase. Antiviral activity of the carbocyclic 2'-deoxyguanosine enantiomers. Journal of medicinal chemistry, 1987, Volume: 30, Issue:4 Topics: 2-Aminopurine; Adenosine; Adenosine Deaminase; Animals; Antiviral Agents; Cytopathogenic Effect, Viral; Deoxyguanosine; Nucleoside Deaminases; Purine Nucleosides; Simplexvirus; Stereoisomerism; Structure-Activity Relationship; Vero Cells	1987
Differences in the metabolism and metabolic effects of the carbocyclic adenosine analogs, neplanocin A and aristeromycin. Molecular pharmacology, 1986, Volume: 29, Issue:4 Topics: Adenosine; Adenosine Deaminase; Adenosine Triphosphate; AMP Deaminase; Animals; Cell Division; Cell Line; Guanine; Guanosine Triphosphate; Hypoxanthine; Hypoxanthines; Isomerism; Kinetics; Leukemia L1210; Mice	1986
Carbocyclic inosine as a potent anti-leishmanial agent: the metabolism and selective cytotoxic effects of carbocyclic inosine in promastigotes of Leishmania tropica and Leishmania donovani. Biochemical and biophysical research communications, 1986, Feb-13, Volume: 134, Issue:3 Topics: Adenosine; Animals; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Inosine; Leishmania donovani; Leishmania tropica; Mice; Trypanocidal Agents	1986
Creation of novel chiral synthons with enzymes: application to enantioselective synthesis of antibiotics. Ciba Foundation symposium, 1985, Volume: 111 Topics: Adenosine; Amino Acids, Diamino; Animals; Anti-Bacterial Agents; Binding Sites; Cyclohexanes; Deoxyadenosines; Enzymes; Esterases; In Vitro Techniques; Models, Chemical; Showdomycin; Stereoisomerism; Swine; Thienamycins	1985
Isolation and characterization of a new aristeromycin analog. The Journal of antibiotics, 1985, Volume: 38, Issue:8 Topics: Adenosine; Animals; Chemical Phenomena; Chemistry; Magnetic Resonance Spectroscopy; Mice	1985
Resolution of aristeromycin enantiomers. Journal of medicinal chemistry, 1985, Volume: 28, Issue:10 Topics: Adenosine; Antimetabolites, Antineoplastic; Antiviral Agents; Cell Survival; Stereoisomerism; Structure-Activity Relationship; Virus Replication	1985
Enantioselective synthesis of new analogues of neplanocin A. Nucleic acids symposium series, 1983, Issue:12 Topics: Adenosine; Chemical Phenomena; Chemistry; Stereoisomerism; Structure-Activity Relationship	1983
Irreversible inhibition of S-adenosylhomocysteine hydrolase by nucleoside analogs. Archives of biochemistry and biophysics, 1981, Volume: 207, Issue:1 Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosylhomocysteinase; Animals; Cattle; Chemical Phenomena; Chemistry; Hydrolases; Kinetics; Liver; Nucleosides; Structure-Activity Relationship; Vidarabine	1981
Induction of erythroid differentiation in leukaemic K562 cells by an S-adenosylhomocysteine hydrolase inhibitor, aristeromycin. Biochemical and biophysical research communications, 1995, Feb-06, Volume: 207, Issue:1 Topics: 3T3 Cells; Adenosine; Adenosylhomocysteinase; Animals; Cell Differentiation; Cell Division; Cell Line; Cell Line, Transformed; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Formycins; Genes, abl; Humans; Hydrolases; Isomerism; Kinetics; Leukemia, Erythroblastic, Acute; Mice; Tubercidin; Tumor Cells, Cultured	1995
Highly stereoselective synthesis of bicyclic-sugar adenosine derivatives via Diels-Alder reaction. Nucleic acids symposium series, 1993, Issue:29 Topics: Acrylates; Adenosine; Carbohydrates; Molecular Structure; Stereoisomerism	1993
Effects of 4'-modified analogs of aristeromycin on the metabolism of S-adenosyl-L-homocysteine in murine L929 cells. Molecular pharmacology, 1993, Volume: 43, Issue:6 Topics: Adenosine; Adenosylhomocysteinase; Animals; Humans; Hydrolases; L Cells; Liver; Mice; Placenta; Rats; Recombinant Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine	1993
Cyclic aristeromycin diphosphate ribose: a potent and poorly hydrolysable Ca(2+)-mobilising mimic of cyclic adenosine diphosphate ribose. FEBS letters, 1996, Feb-05, Volume: 379, Issue:3 Topics: Adenosine; Adenosine Diphosphate Ribose; Animals; Calcium; Cyclic ADP-Ribose; Hydrolysis; Ovum; Phosphorylation; Sea Urchins	1996
Inhibitors of infectious pancreatic necrosis virus (IPNV) replication. Antiviral research, 1996, Volume: 29, Issue:2-3 Topics: Adenosine; Adenosylhomocysteinase; Amides; Animals; Antiviral Agents; Cell Line; DNA; Foscarnet; Hydrolases; IMP Dehydrogenase; Infectious pancreatic necrosis virus; Orotidine-5'-Phosphate Decarboxylase; Pyrazoles; Ribavirin; Ribonucleosides; Ribose; Salmon; Viral Plaque Assay; Virus Replication	1996
(+)-7-Deaza-5'-noraristeromycin as an anti-trypanosomal agent. Journal of medicinal chemistry, 1997, Feb-14, Volume: 40, Issue:4 Topics: Adenosine; Adenosylhomocysteinase; Animals; Antiviral Agents; Drug Design; Hydrolases; Stereoisomerism; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei	1997
Carbocyclic oxetanocins lacking the C-3' methylene. Journal of medicinal chemistry, 1997, Apr-25, Volume: 40, Issue:9 Topics: Adenine; Adenosine; Animals; Antiviral Agents; Cells, Cultured; Giant Cells; Guanine; Herpesvirus 1, Human; Herpesvirus 3, Human; HIV-1; HIV-2; Humans; Magnetic Resonance Spectroscopy; Molecular Structure; Viruses	1997
Induction of cellular differentiation and apoptosis by signal transduction inhibitors. Advances in enzyme regulation, 1997, Volume: 37 Topics: Adenosine; Animals; Antineoplastic Agents; Apoptosis; Cell Differentiation; Cell Division; Formycins; Gene Expression Regulation, Neoplastic; Genes, abl; Humans; Hydroquinones; Molecular Structure; Neoplasms; Protein Tyrosine Phosphatases; Signal Transduction; Tubercidin; Tumor Cells, Cultured	1997
Structure of DNA containing aristeromycin analog. Nucleic acids symposium series, 1997, Issue:37 Topics: Adenine; Adenosine; Base Sequence; Calorimetry; Cyclopentanes; DNA; Nucleic Acid Denaturation; Oligodeoxyribonucleotides; Thermodynamics	1997
Novel carbocyclic nucleosides containing a cyclobutyl ring. Guanosine and adenosine analogues. Nucleosides & nucleotides, 1998, Volume: 17, Issue:7 Topics: Acids, Carbocyclic; Adenosine; Antiviral Agents; Guanosine; Magnetic Resonance Spectroscopy; Models, Chemical; Nucleosides	1998
Synthesis and biological evaluation of a carbocyclic azanoraristeromycin siderophore conjugate. Nucleosides & nucleotides, 1999, Volume: 18, Issue:2 Topics: Adenosine; Animals; Anti-HIV Agents; Antiviral Agents; Cell Division; Ferrichrome; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Molecular Structure; Siderophores; T-Lymphocytes; Tumor Cells, Cultured	1999
Characterization of metabolites in intact Streptomyces citricolor culture supernatants using high-resolution nuclear magnetic resonance and directly coupled high-pressure liquid chromatography-nuclear magnetic resonance spectroscopy. Analytical biochemistry, 1999, Jun-01, Volume: 270, Issue:2 Topics: Acetic Acid; Adenosine; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Citric Acid; Culture Media, Conditioned; Fructose; Magnetic Resonance Spectroscopy; Phenethylamines; Streptomyces; Succinic Acid; Trehalose; Uridine	1999
The design and synthesis of inhibitors of adenosine 5'-monophosphate deaminase. Bioorganic & medicinal chemistry letters, 1999, Jul-19, Volume: 9, Issue:14 Topics: Adenosine; Adenosine Triphosphate; AMP Deaminase; Coformycin; Drug Design; Drug Evaluation, Preclinical; Enzyme Inhibitors; Formycins; Herbicides; Inhibitory Concentration 50; Phosphorylation; Purine Nucleosides; Ribonucleosides; Structure-Activity Relationship	1999
A novel, one-pot ring expansion of cyclobutanones. Syntheses of carbovir and aristeromycin. The Journal of organic chemistry, 2000, Mar-24, Volume: 65, Issue:6 Topics: Adenosine; Anti-HIV Agents; Butanones; Dideoxynucleosides; Stereoisomerism	2000
Ring-Constrained (N)-methanocarba nucleosides as adenosine receptor agonists: independent 5'-uronamide and 2'-deoxy modifications. Bioorganic & medicinal chemistry letters, 2001, May-21, Volume: 11, Issue:10 Topics: Adenine; Adenosine; Animals; Binding, Competitive; Brain; Cell Line; Cell Membrane; CHO Cells; Cricetinae; Cyclopentanes; Humans; Nucleosides; Protein Binding; Purinergic P1 Receptor Agonists; Rats; Receptors, Purinergic P1; Structure-Activity Relationship; Transfection	2001
Syntheses of D- and L-cyclopentenone derivatives using ring-closing metathesis: versatile intermediates for the synthesis of D- and L-carbocyclic nucleosides. The Journal of organic chemistry, 2001, Sep-21, Volume: 66, Issue:19 Topics: Adenosine; Adenosylhomocysteinase; Ascorbic Acid; Cyclopentanes; Hydrolases; Nucleosides	2001
Stereoselective synthesis of a novel carbocyclic nucleoside. The Journal of organic chemistry, 2001, Nov-02, Volume: 66, Issue:22 Topics: Adenosine; Antiviral Agents; Dideoxyadenosine; Stereoisomerism	2001
Synthesis of enantiomerically-pure [13C]aristeromycylcobalamin and its reactivity in dioldehydratase, glyceroldehydratase, ethanolamine ammonia-lyase and methylmalonyl-CoA mutase reactions. Chemistry (Weinheim an der Bergstrasse, Germany), 2003, Feb-03, Volume: 9, Issue:3 Topics: Adenosine; Carbon Radioisotopes; Catalysis; Cobamides; Electron Spin Resonance Spectroscopy; Enzyme Activation; Ethanolamine Ammonia-Lyase; Hydro-Lyases; Isotope Labeling; Kinetics; Methane; Methylmalonyl-CoA Mutase; Nitroparaffins; Propanediol Dehydratase; Stereoisomerism; Substrate Specificity	2003
9-deaza-5'-noraristeromycin. Bioorganic & medicinal chemistry, 2003, Jul-31, Volume: 11, Issue:15 Topics: Adenosine	2003
Synthesis of noraristeromycin analogues possessing SAH hydrolase inhibitory activity for the development of antimalaria agents. Nucleic acids research. Supplement (2001), 2002, Issue:2 Topics: Adenosine; Adenosylhomocysteinase; Animals; Antimalarials; Humans; Hydrolases; Plasmodium falciparum; Recombinant Proteins	2002
Activation of methionine for transmethylation. IV. The failure of 3,5'-cycloadenosine to replace adenosine triphosphate. Biochimica et biophysica acta, 1960, Feb-12, Volume: 38 Topics: Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Methionine; Nucleosides; Nucleotides	1960
Highly stereoselective synthesis of aristeromycin through dihydroxylation of 4-aryl-1-azido-2-cyclopentenes. The Journal of organic chemistry, 2004, Feb-06, Volume: 69, Issue:3 Topics: Adenosine; Azides; Benzene Derivatives; Cyclopentanes; Hydroxylation; Molecular Conformation; Stereoisomerism	2004
Preparation of carbocyclic S-adenosylazamethionine accompanied by a practical synthesis of (-)-aristeromycin. The Journal of organic chemistry, 2004, May-28, Volume: 69, Issue:11 Topics: Adenosine; Aza Compounds; Molecular Conformation; S-Adenosylmethionine	2004
Population pharmacokinetic-pharmacodynamic modelling of the anti-hyperalgesic effect of 5'deoxy-N6-cylopentyladenosine in the mononeuropathic rat. European journal of pharmacology, 2004, Nov-03, Volume: 504, Issue:1-2 Topics: Adenosine; Analgesics; Animals; Hyperalgesia; Male; Mononeuropathies; Pain Measurement; Rats	2004
Mutational analyses of Plasmodium falciparum and human S-adenosylhomocysteine hydrolases. Molecular and biochemical parasitology, 2005, Volume: 143, Issue:2 Topics: Adenosine; Adenosylhomocysteinase; Amino Acid Substitution; Animals; Enzyme Inhibitors; Humans; Kinetics; Models, Molecular; Molecular Conformation; Mutagenesis, Site-Directed; Plasmodium falciparum; Protein Conformation; Recombinant Proteins; Static Electricity	2005
3'-Fluoro-3'-deoxy-5'-noraristeromycin derivatives: synthesis and antiviral analysis. Bioorganic & medicinal chemistry, 2006, Jul-15, Volume: 14, Issue:14 Topics: Adenosine; Animals; Antiviral Agents; Drug Design; Humans; In Vitro Techniques; Microbial Sensitivity Tests; Structure-Activity Relationship; Viruses	2006
5'-methylaristeromycin and related derivatives. The Journal of organic chemistry, 2006, Oct-27, Volume: 71, Issue:22 Topics: Adenosine; Antiviral Agents; Cyclopentanes; Molecular Structure	2006
5'-Fluoro-5'-deoxyaristeromycin. Bioorganic & medicinal chemistry letters, 2008, Jan-01, Volume: 18, Issue:1 Topics: Adenosine; Animals; Antiviral Agents; Cell Line; Chlorocebus aethiops; Deoxyadenosines; HeLa Cells; Humans; Hydrocarbons, Fluorinated; Vero Cells	2008
Synthesis of 2-modified aristeromycins and their analogs as potent inhibitors against Plasmodium falciparum S-adenosyl-L-homocysteine hydrolase. Bioorganic & medicinal chemistry, 2008, Apr-01, Volume: 16, Issue:7 Topics: Adenosine; Adenosylhomocysteinase; Animals; Antimalarials; Enzyme Inhibitors; Molecular Structure; Plasmodium falciparum; Structure-Activity Relationship	2008
Synthesis of 3',4'-epoxynoraristeromycin analogs for molecular labeling probe of S-adenosyl-l-homocysteine hydrolase. Bioorganic & medicinal chemistry, 2008, Jul-01, Volume: 16, Issue:13 Topics: Adenosine; Adenosylhomocysteinase; Animals; Humans; Magnetic Resonance Spectroscopy; Molecular Probes; Molecular Structure; Plasmodium falciparum	2008
Synthesis of carbocyclic 2-substituted adenine nucleoside and related analogs. Nucleosides, nucleotides & nucleic acids, 2008, Volume: 27, Issue:10 Topics: Adenosine; Animals; Molecular Structure; N-Glycosyl Hydrolases; Plasmodium falciparum	2008
Development of a new tacaribe arenavirus infection model and its use to explore antiviral activity of a novel aristeromycin analog. PloS one, 2010, Sep-16, Volume: 5, Issue:9 Topics: Adenosine; Animals; Antiviral Agents; Arenaviridae Infections; Arenaviruses, New World; Chlorocebus aethiops; Cricetinae; Disease Models, Animal; Female; Humans; Male; Mesocricetus; Mice; Mice, Knockout; Vero Cells; Virus Replication	2010
AdoHcy hydrolase of Trichomonas vaginalis: studies of the effects of 5'-modified adenosine analogues and related 6-N-cyclopropyl derivatives. Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24 Topics: Adenosine; Adenosylhomocysteinase; Amino Acid Sequence; Antiprotozoal Agents; Cyclopropanes; Molecular Sequence Data; Sequence Alignment; Structure-Activity Relationship; Trichomonas vaginalis	2010
Acetoxy Meldrum's acid: a versatile acyl anion equivalent in the Pd-catalyzed asymmetric allylic alkylation. Organic letters, 2011, Jun-17, Volume: 13, Issue:12 Topics: Adenosine; Alkylation; Allyl Compounds; Anions; Anti-HIV Agents; Catalysis; Combinatorial Chemistry Techniques; Dideoxynucleosides; Dioxanes; Molecular Structure; Palladium; Stereoisomerism	2011
Design and synthesis of amide derivatives as S-adenosyl-L-homocysteine hydrolase inhibitors. Chemical & pharmaceutical bulletin, 2014, Volume: 62, Issue:1 Topics: Adenosine; Amides; Homocysteine; Hydrolases; Structure-Activity Relationship	2014
Comparative performance of S-adenosyl-L-methionine biosynthesis and degradation in Pichia pastoris using different promoters and novel consumption inhibitors. Enzyme and microbial technology, 2014, Feb-05, Volume: 55 Topics: Adenosine; Adenosine Triphosphate; Alcohol Oxidoreductases; Ethanol; Fermentation; Fungal Proteins; Genes, Synthetic; Glutathione; Glyceraldehyde-3-Phosphate Dehydrogenases; Hydrogen Peroxide; Methanol; Methionine Adenosyltransferase; Pichia; Promoter Regions, Genetic; Recombinant Fusion Proteins; S-Adenosylmethionine; Spermidine; Transcription, Genetic	2014
Structural insights into the reaction mechanism of S-adenosyl-L-homocysteine hydrolase. Scientific reports, 2015, Nov-17, Volume: 5 Topics: Adenosine; Adenosylhomocysteinase; Amino Acid Sequence; Animals; Binding Sites; Biocatalysis; Crystallography, X-Ray; Hydrolysis; Mice; Molecular Dynamics Simulation; Molecular Sequence Data; Protein Structure, Tertiary; S-Adenosylhomocysteine; Sequence Alignment; Substrate Specificity	2015
Synthesis and anti-HBV activity of α-stereoisomer of aristeromycin based analogs. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine; Antiviral Agents; Cell Line; Cell Survival; Crystallography, X-Ray; Cyclopentanes; Hepatitis B virus; Humans; Molecular Conformation; Pyrimidines; Stereoisomerism; Virus Replication	2016
Five-Membered Cyclitol Phosphate Formation by a myo-Inositol Phosphate Synthase Orthologue in the Biosynthesis of the Carbocyclic Nucleoside Antibiotic Aristeromycin. Chembiochem : a European journal of chemical biology, 2016, Nov-17, Volume: 17, Issue:22 Topics: Adenosine; Anti-Bacterial Agents; Bacterial Proteins; Cosmids; Cyclitols; Magnetic Resonance Spectroscopy; Multigene Family; Myo-Inositol-1-Phosphate Synthase; Nucleosides; Phosphorus-Oxygen Lyases; Spectrometry, Mass, Electrospray Ionization; Streptomyces coelicolor	2016
Aristeromycin and DZNeP cause growth inhibition of prostate cancer via induction of mir-26a. European journal of pharmacology, 2017, Oct-05, Volume: 812 Topics: Adenosine; Adenosylhomocysteinase; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Enhancer of Zeste Homolog 2 Protein; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Male; MicroRNAs; Prostatic Neoplasms; RNA, Small Interfering; Transcriptional Activation	2017
Coordinated Biosynthesis of the Purine Nucleoside Antibiotics Aristeromycin and Coformycin in Actinomycetes. Applied and environmental microbiology, 2018, 11-15, Volume: 84, Issue:22 Topics: Actinobacteria; Adenosine; Anti-Bacterial Agents; Bacterial Proteins; Biosynthetic Pathways; Coformycin; GMP Reductase; Purine Nucleosides	2018
Rhodium catalyzed stereospecific reductive carbocyclization of 1,6-enynes and synthesis of 4'-methyl-6'-substituted aristeromycins. Nucleosides, nucleotides & nucleic acids, 2019, Volume: 38, Issue:6 Topics: Adenosine; Alkynes; Catalysis; Cyclization; Humans; Molecular Structure; Oxidation-Reduction; Rhodium; Stereoisomerism	2019
Stereochemistry in the Reaction of the Biochemistry, 2019, 12-24, Volume: 58, Issue:51 Topics: Adenosine; Models, Molecular; Myo-Inositol-1-Phosphate Synthase; Protein Conformation; Stereoisomerism; Streptomyces	2019