arginyl-glycyl-aspartic acid and echistatin

arginyl-glycyl-aspartic acid has been researched along with echistatin in 49 studies

Research

Studies (49)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	27 (55.10)	18.2507
2000's	16 (32.65)	29.6817
2010's	6 (12.24)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Carter, BG; Cooke, RM; Hartshorn, MJ; Herzyk, P; Hubbard, RE; Murray-Rust, P	1
Williams, JA	1
Bovermann, G; Breckenridge, R; Dalvit, C; Metternich, R; Widmer, H	1
Atkinson, RA; Lepage, P; Pelton, JT; Saudek, V	1
Atkinson, RA; Pelton, JT; Saudek, V	2
Ali, FE; Dorey, EL; Greig, R; Helfrich, MH; Horton, MA; Nesbitt, SA; Nichols, A; Samanen, J; Stadel, JM	1
Davison, I; Helfrich, MH; Horton, MA; Mason, WT; Shankar, G	1
Einhorn, TA; Garsky, V; Gould, RJ; Majeska, RJ; Murray, J; Sato, M; Tashjian, AH	1
Baas, C; de Groot, H; Löwik, C; Mouthaan, H; Papapoulos, S; van der Pluijm, G	1
Brown, S; Foster, MR; Hann, M; Hornby, EJ; Kitchin, J; Pike, N; Ward, P	1
Baum, J; Chen, Y; Garsky, VM; Kominos, D; Levy, RM; Naylor, AM; Pitzenberger, SM; Sanyal, G; Suri, AK	1
Calvete, JJ; McLane, MA; Niewiarowski, S; Stewart, GJ	1
Kowalska, MA; McLane, MA; Niewiarowski, S; Shattil, SJ; Silver, L	1
Brown, S; Foster, MR; Hann, M; Hornby, EJ; Kitchin, J; Ward, P	1
Caulfield, MP; Fisher, JE; Garsky, VM; Gould, RJ; Quartuccio, HA; Rodan, GA; Rosenblatt, M; Sato, M	1
Oursler, MJ; Spelsberg, TC	1
Chen, MS; Huang, TF; Hung, PT; Liu, KR; Yang, CH	1
Kidera, A; Yamada, T	1
Fong, JH; Ingber, DE	1
Hu, M; Li, H; Li, X	1
Calvete, JJ; Marcinkiewicz, C; McLane, MA; Niewiarowski, S; Vijay-Kumar, S	1
Marcinkiewicz, C; McLane, MA; Niewiarowski, S; Vijay-Kumar, S	1
Cornelissen, IM; Danen, EH; Marcinkiewicz, C; Niewiarowski, S; Pachter, JA; Ruiter, DJ; van Kraats, AA; van Muijen, GN	1
Clemmons, DR; Duan, C; Zheng, B	1
Ali, FE; Bennett, D; Bondinell, W; Chen, W; Heys, JR; Hwang, SM; Johanson, K; Ku, TW; Landvatter, SW; Nichols, AJ; Powers, DA; Samanen, J; Stadel, JM; Wong, A	1
Armstrong, L; Kumar, CC; Nie, H; Tsarbopoulos, A; Vijay-Kumar, S; Zhang, R	1
Beyler, SA; Cullinan, E; Gui, Y; Illera, MJ; Lessey, BA; Yuan, L	1
Thibault, G	1
Lapalme, G; Tardif, P; Thibault, G	1
Belvisi, L; Bernardi, A; Carminati, P; Castorina, M; Checchia, A; Cupelli, A; Giannini, G; Manzoni, L; Pisano, C; Potenza, D; Scolastico, C	1
Armstrong, L; Kumar, CC; Liu, M; Malkowski, M; Nechuta, T; Neustadt, B; Presta, M; Smith, EM; Tanghetti, E; Varner, J; Yaremko, B; Yin, Z	1
Aoki, M; Ikeda, T; Manaka, A; Nakaike, S; Sato, M; Tanaka, M; Toda, Y; Yamane, Y	1
Chavis, P; Westbrook, G	1
Bitan, G; Chorev, M; Mierke, DF; Rosenblatt, M; Scheibler, L	1
Alexander, JM; Chorev, M; Mierke, DF; Rosenblatt, M; Wittelsberger, A; Yahalom, D	1
Attardo, G; Bergeron, F; Bowlin, T; Bubenik, M; Chan, L; Gourdeau, H; Grouix, B; Leblond, L; Meerovitch, K; Poirier, C	1
Archer, L; Dolce, C; Holliday, LS; Morris-Wiman, JA; Vakani, A	1
Bolontrade, MF; Duan, X; Jia, SF; Kleinerman, ES; Langley, RR; Zhou, Z	1
Evans, C; Talic, NF; Zaki, AM	1
Del Gatto, A; Del Vecchio, S; Grieco, P; Iommelli, F; Novellino, E; Pedone, C; Salvatore, M; Saviano, M; Zaccaro, L; Zannetti, A	1
Cai, W; Chen, K; Chen, X; Gambhir, SS; Li, ZB	1
De Luca, S; Del Gatto, A; Del Vecchio, S; Grieco, P; Iommelli, F; Novellino, E; Panico, M; Papaccioli, A; Pedone, C; Salvatore, M; Saviano, M; Sommella, J; Speranza, A; Zaccaro, L; Zannetti, A	1
Chen, X; Jacobson, O; Kiesewetter, DO; Liu, S; Ma, Y; Niu, G; Sun, X; Szajek, LP; Weiss, ID; Yan, Y; Zhu, L	1
Chen, X; Jacobson, O; Kiesewetter, DO; Ma, Y; Niu, G; Sun, X; Weiss, ID; Zhu, L	1
Greguric, I; Howell, NR; Katsifis, A; Pellegrini, P; Szabo, AM	1
Chang, YS; Chang, YT; Chen, YC; Cheng, CH; Chuang, WJ; Huang, CH; Lee, JC; Shiu, JH	1
Carver, W; Fowlkes, V; Goldsmith, EC; Wilson, CG	1
Capasso, D; de Paola, I; Di Gaetano, S; Farina, B; Fattorusso, R; Gatto, AD; Liguoro, A; Malgieri, G; Pedone, PV; Russo, L; Saviano, M; Zaccaro, L	1

Reviews

2 review(s) available for arginyl-glycyl-aspartic acid and echistatin

Article	Year
Disintegrins: RGD-containing proteins which inhibit cell/matrix interactions (adhesion) and cell/cell interactions (aggregation) via the integrin receptors. Pathologie-biologie, 1992, Volume: 40, Issue:8 Topics: Cell Adhesion; Cell Aggregation; Fibrinolytic Agents; Humans; Integrins; Intercellular Signaling Peptides and Proteins; Oligopeptides; Peptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombosis; Viper Venoms	1992
Echistatin, a potential new drug for osteoporosis. Endocrinology, 1993, Volume: 132, Issue:3 Topics: Animals; Bone Resorption; Humans; Integrins; Intercellular Signaling Peptides and Proteins; Oligopeptides; Osteoporosis; Peptides; Platelet Aggregation Inhibitors; Viper Venoms	1993

Article

Year

Disintegrins: RGD-containing proteins which inhibit cell/matrix interactions (adhesion) and cell/cell interactions (aggregation) via the integrin receptors.

Pathologie-biologie, 1992, Volume: 40, Issue:8

Topics: Cell Adhesion; Cell Aggregation; Fibrinolytic Agents; Humans; Integrins; Intercellular Signaling Peptides and Proteins; Oligopeptides; Peptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombosis; Viper Venoms

1992

Echistatin, a potential new drug for osteoporosis.

Endocrinology, 1993, Volume: 132, Issue:3

Topics: Animals; Bone Resorption; Humans; Integrins; Intercellular Signaling Peptides and Proteins; Oligopeptides; Osteoporosis; Peptides; Platelet Aggregation Inhibitors; Viper Venoms

1993

Other Studies

47 other study(ies) available for arginyl-glycyl-aspartic acid and echistatin

Article	Year
The solution structure of echistatin: evidence for disulphide bond rearrangement in homologous snake toxins. Protein engineering, 1992, Volume: 5, Issue:6 Topics: Amino Acid Sequence; Chemical Phenomena; Chemistry, Physical; Cystine; Fibrinogen; Intercellular Signaling Peptides and Proteins; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Oligopeptides; Peptides; Protein Folding; Protein Structure, Tertiary; Sequence Alignment; Snake Venoms; Viper Venoms	1992
1H NMR studies of echistatin in solution. Sequential resonance assignments and secondary structure. European journal of biochemistry, 1991, Dec-05, Volume: 202, Issue:2 Topics: Amino Acid Sequence; Disulfides; Intercellular Signaling Peptides and Proteins; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Oligopeptides; Peptides; Platelet Membrane Glycoproteins; Protein Conformation; Sequence Homology, Nucleic Acid; Solutions; Viper Venoms	1991
The secondary structure of echistatin from 1H-NMR, circular-dichroism and Raman spectroscopy. European journal of biochemistry, 1991, Dec-05, Volume: 202, Issue:2 Topics: Amino Acid Sequence; Circular Dichroism; Intercellular Signaling Peptides and Proteins; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Oligopeptides; Peptides; Protein Conformation; Spectrum Analysis, Raman; Temperature; Viper Venoms	1991
Three-dimensional structure of echistatin, the smallest active RGD protein. Biochemistry, 1991, Jul-30, Volume: 30, Issue:30 Topics: Amino Acid Sequence; Animals; Binding Sites; Cysteine; Hydrogen Bonding; Intercellular Signaling Peptides and Proteins; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Oligopeptides; Peptides; Protein Conformation; Snakes; Spectrum Analysis; Viper Venoms	1991
Modulation of vitronectin receptor-mediated osteoclast adhesion by Arg-Gly-Asp peptide analogs: a structure-function analysis. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1993, Volume: 8, Issue:2 Topics: Amino Acid Sequence; Animals; Bone and Bones; Cell Adhesion; Chick Embryo; Dentin; Glass; Intercellular Signaling Peptides and Proteins; Molecular Sequence Data; Oligopeptides; Osteoclasts; Peptides; Peptides, Cyclic; Rats; Receptors, Cytoadhesin; Receptors, Vitronectin; Structure-Activity Relationship; Viper Venoms	1993
Integrin receptor-mediated mobilisation of intranuclear calcium in rat osteoclasts. Journal of cell science, 1993, Volume: 105 ( Pt 1) Topics: Animals; Antibodies, Monoclonal; Calcitonin; Calcium; Cell Adhesion; Cell Communication; Cell Nucleus; Cells, Cultured; Extracellular Matrix; Intercellular Signaling Peptides and Proteins; Oligopeptides; Osteoclasts; Peptides; Rats; Receptors, Cytoadhesin; Receptors, Vitronectin; Viper Venoms	1993
Structure-activity studies of the s-echistatin inhibition of bone resorption. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1994, Volume: 9, Issue:9 Topics: Amino Acid Sequence; Animals; Bone Neoplasms; Bone Resorption; Cell Adhesion; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Giant Cell Tumor of Bone; Humans; Intercellular Signaling Peptides and Proteins; Mice; Microscopy, Confocal; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Molecular Sequence Data; Oligopeptides; Organ Culture Techniques; Osteoclasts; Peptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Viper Venoms	1994
Echistatin: the refined structure of a disintegrin in solution by 1H NMR and restrained molecular dynamics. International journal of peptide and protein research, 1994, Volume: 43, Issue:6 Topics: Amino Acid Sequence; Computer Simulation; Disintegrins; Intercellular Signaling Peptides and Proteins; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Sequence Data; Oligopeptides; Peptides; Platelet Aggregation Inhibitors; Protein Structure, Secondary; Solutions; Thermodynamics; Viper Venoms	1994
Integrins and osteoclastic resorption in three bone organ cultures: differential sensitivity to synthetic Arg-Gly-Asp peptides during osteoclast formation. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1994, Volume: 9, Issue:7 Topics: Amino Acid Sequence; Animals; Bone Resorption; Calcium; Dose-Response Relationship, Drug; Female; Integrins; Intercellular Signaling Peptides and Proteins; Mice; Oligopeptides; Organ Culture Techniques; Osteoclasts; Peptides; Pregnancy; Viper Venoms	1994
Inhibition of human platelet aggregation by GR91669, a prototype fibrinogen receptor antagonist. Thrombosis research, 1994, Aug-01, Volume: 75, Issue:3 Topics: Amino Acid Sequence; Animals; Binding, Competitive; Blood Platelets; Callithrix; Cell Adhesion; Dipeptides; Endothelium, Vascular; Granulocytes; Humans; Intercellular Signaling Peptides and Proteins; Molecular Sequence Data; Oligopeptides; Peptides; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Serotonin; Structure-Activity Relationship; Thiourea; Viper Venoms	1994
Three-dimensional structure of echistatin and dynamics of the active site. Journal of biomolecular NMR, 1994, Volume: 4, Issue:3 Topics: Amino Acid Sequence; Binding Sites; Calorimetry; Computer Graphics; Intercellular Signaling Peptides and Proteins; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Oligopeptides; Peptides; Protein Conformation; Protein Folding; Protein Structure, Secondary; Viper Venoms	1994
Characterization of the cross-linking site of disintegrins albolabrin, bitistatin, echistatin, and eristostatin on isolated human platelet integrin GPIIb/IIIa. Biochemical and biophysical research communications, 1994, Jul-15, Volume: 202, Issue:1 Topics: Amino Acid Sequence; Binding Sites; Cross-Linking Reagents; Crotalid Venoms; Humans; Intercellular Signaling Peptides and Proteins; Oligopeptides; Peptides; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Snake Venoms; Viper Venoms	1994
Interaction of disintegrins with the alpha IIb beta 3 receptor on resting and activated human platelets. The Biochemical journal, 1994, Jul-15, Volume: 301 ( Pt 2) Topics: Adenosine Diphosphate; Blood Platelets; Cross-Linking Reagents; Crotalid Venoms; Disintegrins; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Humans; Intercellular Signaling Peptides and Proteins; Iodine Radioisotopes; Peptides; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Snake Venoms; Viper Venoms	1994
Improved potency and specificity of Arg-Gly-Asp (RGD) containing peptides as fibrinogen receptor blocking drugs. Thrombosis research, 1993, Nov-01, Volume: 72, Issue:3 Topics: Amino Acid Sequence; Humans; Intercellular Signaling Peptides and Proteins; Molecular Sequence Data; Oligopeptides; Peptides; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Radioligand Assay; Viper Venoms	1993
Inhibition of osteoclastic bone resorption in vivo by echistatin, an "arginyl-glycyl-aspartyl" (RGD)-containing protein. Endocrinology, 1993, Volume: 132, Issue:3 Topics: Animals; Bone and Bones; Bone Resorption; Calcium; Intercellular Signaling Peptides and Proteins; Male; Oligopeptides; Osteoclasts; Parathyroid Hormone; Parathyroidectomy; Peptides; Rats; Rats, Sprague-Dawley; Thyroidectomy; Viper Venoms	1993
Inhibition of retinal pigment epithelial cell-induced tractional retinal detachment by disintegrins, a group of Arg-Gly-Asp-containing peptides from viper venom. Investigative ophthalmology & visual science, 1996, Volume: 37, Issue:5 Topics: Amino Acid Sequence; Animals; Antineoplastic Agents; Cattle; Cell Adhesion; Cells, Cultured; Crotalid Venoms; Dose-Response Relationship, Drug; Extracellular Matrix; Fluorescent Antibody Technique, Indirect; Integrins; Intercellular Signaling Peptides and Proteins; Molecular Sequence Data; Oligopeptides; Peptides; Pigment Epithelium of Eye; Platelet Aggregation Inhibitors; Rabbits; Retinal Detachment; Viper Venoms; Vitreoretinopathy, Proliferative; Vitreous Body	1996
Tailoring echistatin to possess higher affinity for integrin alpha(IIb)beta(3). FEBS letters, 1996, May-27, Volume: 387, Issue:1 Topics: Amino Acid Sequence; Disulfides; Humans; Intercellular Signaling Peptides and Proteins; Models, Molecular; Molecular Sequence Data; Mutation; Oligopeptides; Peptides; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Protein Conformation; Spectrometry, Mass, Fast Atom Bombardment; Structure-Activity Relationship; Tumor Cells, Cultured	1996
Modulation of adhesion-dependent cAMP signaling by echistatin and alendronate. Biochemical and biophysical research communications, 1996, Apr-05, Volume: 221, Issue:1 Topics: Alendronate; Binding Sites; Cell Adhesion; Cyclic AMP; Diphosphonates; Endothelium, Vascular; Extracellular Matrix; Humans; Intercellular Signaling Peptides and Proteins; Oligopeptides; Peptides; Signal Transduction	1996
[Site-directed mutagenesis of the gene of Echistatin Leu14-Lys15-Glu16]. Yi chuan xue bao = Acta genetica Sinica, 1996, Volume: 23, Issue:2 Topics: Amino Acid Sequence; Base Sequence; Humans; Intercellular Signaling Peptides and Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligopeptides; Peptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Structure-Activity Relationship; Viper Venoms	1996
Importance of the structure of the RGD-containing loop in the disintegrins echistatin and eristostatin for recognition of alpha IIb beta 3 and alpha v beta 3 integrins. FEBS letters, 1996, Aug-05, Volume: 391, Issue:1-2 Topics: Amino Acid Sequence; Animals; CHO Cells; Computer Simulation; Cricetinae; Disulfides; Humans; Intercellular Signaling Peptides and Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligopeptides; Oxalates; Oxalic Acid; Peptide Fragments; Peptides; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Point Mutation; Protein Structure, Secondary; Receptors, Vitronectin; Recombinant Proteins; Thermodynamics; Transfection; Trypsin; Viper Venoms; Viperidae	1996
Significance of RGD loop and C-terminal domain of echistatin for recognition of alphaIIb beta3 and alpha(v) beta3 integrins and expression of ligand-induced binding site. Blood, 1997, Aug-15, Volume: 90, Issue:4 Topics: Animals; Binding Sites; Blood Platelets; CHO Cells; Cricetinae; Epitopes; Humans; Intercellular Signaling Peptides and Proteins; Ligands; Models, Molecular; Oligopeptides; Peptides; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Receptors, Vitronectin; Structure-Activity Relationship; Transfection; Viper Venoms	1997
The disintegrin eristostatin interferes with integrin alpha 4 beta 1 function and with experimental metastasis of human melanoma cells. Experimental cell research, 1998, Jan-10, Volume: 238, Issue:1 Topics: Animals; Binding Sites; Humans; Infant, Newborn; Integrin alpha4beta1; Integrins; Intercellular Signaling Peptides and Proteins; Male; Melanocytes; Melanoma; Mice; Mice, Nude; Neoplasm Metastasis; Oligopeptides; Peptides; Platelet Aggregation Inhibitors; Receptors, Lymphocyte Homing; Skin; Skin Neoplasms; Snake Venoms; Viper Venoms	1998
The effect of extracellular matrix proteins on porcine smooth muscle cell insulin-like growth factor (IGF) binding protein-5 synthesis and responsiveness to IGF-I. The Journal of biological chemistry, 1998, Apr-10, Volume: 273, Issue:15 Topics: Animals; Antibodies, Monoclonal; Aorta, Thoracic; Arteriosclerosis; Cell Division; Cells, Cultured; Collagen; DNA; Extracellular Matrix Proteins; Fibronectins; Gene Expression Regulation; Humans; Insulin-Like Growth Factor Binding Protein 2; Insulin-Like Growth Factor Binding Protein 5; Insulin-Like Growth Factor I; Integrins; Intercellular Signaling Peptides and Proteins; Kinetics; Laminin; Muscle, Smooth, Vascular; Oligopeptides; Peptides; Platelet Aggregation Inhibitors; Receptors, Collagen; Recombinant Proteins; RNA, Messenger; Swine; Transcription, Genetic	1998
Binding of [3H]-SK&F 107260 and [3H]-SB 214857 to purified integrin alphaIIbbeta3: evidence for a common binding site for cyclic arginyl-glycinyl-aspartic acid peptides and nonpeptides. The Journal of pharmacology and experimental therapeutics, 1998, Volume: 285, Issue:1 Topics: Binding, Competitive; Blood Platelets; Cations, Divalent; Dose-Response Relationship, Drug; Fibrinogen; Humans; Intercellular Signaling Peptides and Proteins; Oligopeptides; Peptides; Peptides, Cyclic; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex	1998
Chloramine T-induced structural and biochemical changes in echistatin. FEBS letters, 1998, Jun-16, Volume: 429, Issue:3 Topics: Chloramines; Intercellular Signaling Peptides and Proteins; Lactoperoxidase; Mass Spectrometry; Methionine; Models, Molecular; Oligopeptides; Peptides; Platelet Aggregation Inhibitors; Protein Binding; Receptors, Vitronectin; Tosyl Compounds	1998
Blockade of the alpha(v)beta(3) integrin adversely affects implantation in the mouse. Biology of reproduction, 2000, Volume: 62, Issue:5 Topics: Animals; Antibodies, Monoclonal; Blastocyst; Dose-Response Relationship, Drug; Embryo Implantation; Female; Intercellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred Strains; Oligopeptides; Peptides; Pregnancy; Receptors, Vitronectin; Reverse Transcriptase Polymerase Chain Reaction; Serum Albumin, Bovine; Uterus	2000
Sodium dodecyl sulfate-stable complexes of echistatin and RGD-dependent integrins: a novel approach to study integrins. Molecular pharmacology, 2000, Volume: 58, Issue:5 Topics: Animals; Binding Sites; Disintegrins; Fibroblasts; Integrins; Intercellular Signaling Peptides and Proteins; Iodine Radioisotopes; Myocardium; Oligopeptides; Peptides; Radioligand Assay; Rats; Rats, Sprague-Dawley; Sodium Dodecyl Sulfate	2000
Comparative specificity of platelet alpha(IIb)beta(3) integrin antagonists. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 296, Issue:3 Topics: Animals; Binding, Competitive; Blood Platelets; Cells, Cultured; Eptifibatide; Fibroblasts; Heart; Humans; Intercellular Signaling Peptides and Proteins; Oligopeptides; Peptides; Peptides, Cyclic; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Rats; Rats, Sprague-Dawley; Skin	2001
Potent integrin antagonists from a small library of RGD-including cyclic pseudopeptides. Organic letters, 2001, Apr-05, Volume: 3, Issue:7 Topics: Antineoplastic Agents; Bridged Bicyclo Compounds; Cyclization; Intercellular Signaling Peptides and Proteins; Kinetics; Lactams; Molecular Structure; Oligopeptides; Peptide Library; Peptides; Platelet Aggregation Inhibitors; Protein Structure, Secondary; Radioligand Assay; Receptors, Vitronectin	2001
Inhibition of angiogenesis and tumor growth by SCH221153, a dual alpha(v)beta3 and alpha(v)beta5 integrin receptor antagonist. Cancer research, 2001, Mar-01, Volume: 61, Issue:5 Topics: Allantois; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cell Adhesion; Cell Division; Chick Embryo; Chorion; Endothelial Growth Factors; Endothelium, Vascular; Female; Fibroblast Growth Factor 2; Growth Inhibitors; Humans; Integrins; Intercellular Signaling Peptides and Proteins; Lymphokines; Melanoma; Mice; Mice, SCID; Molecular Mimicry; Neovascularization, Pathologic; Neovascularization, Physiologic; Oligopeptides; Peptides; Receptors, Vitronectin; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Vitronectin; Xenograft Model Antitumor Assays	2001
2-Acylimino-3H-thiazoline derivatives: a novel template for platelet GPIIb/IIIa receptor antagonists. Bioorganic & medicinal chemistry letters, 2001, Apr-23, Volume: 11, Issue:8 Topics: Animals; Binding Sites; Blood Platelets; Cell Adhesion; Dogs; Enzyme-Linked Immunosorbent Assay; Fibrinogen; Guinea Pigs; Humans; Inhibitory Concentration 50; Intercellular Signaling Peptides and Proteins; Mice; Oligopeptides; Peptides; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Thiazoles	2001
Integrins mediate functional pre- and postsynaptic maturation at a hippocampal synapse. Nature, 2001, May-17, Volume: 411, Issue:6835 Topics: Animals; Antigens, CD; Calcium-Binding Proteins; Cell Adhesion; Cells, Cultured; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Genistein; Glutamic Acid; Hippocampus; Integrin beta3; Integrins; Intercellular Signaling Peptides and Proteins; Isoflavones; Membrane Glycoproteins; Models, Neurological; Nerve Tissue Proteins; Neurons; Oligopeptides; Peptides; Platelet Membrane Glycoproteins; Presynaptic Terminals; Protein Subunits; Quinazolines; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Synapses; Synaptotagmin I; Synaptotagmins; Tyrphostins	2001
Identification of a contact domain between echistatin and the integrin alpha(v)beta(3) by photoaffinity cross-linking. Biochemistry, 2001, Dec-18, Volume: 40, Issue:50 Topics: Affinity Labels; Amino Acid Sequence; Binding Sites; Cross-Linking Reagents; Drug Design; Humans; In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Kinetics; Ligands; Models, Molecular; Molecular Sequence Data; Oligopeptides; Peptides; Photochemistry; Receptors, Vitronectin; Recombinant Proteins	2001
Identification of the principal binding site for RGD-containing ligands in the alpha(V)beta(3) integrin: a photoaffinity cross-linking study. Biochemistry, 2002, Jul-02, Volume: 41, Issue:26 Topics: Amino Acid Sequence; Binding Sites; Binding, Competitive; Crystallography, X-Ray; Disintegrins; Humans; Intercellular Signaling Peptides and Proteins; Kinetics; Ligands; Models, Molecular; Oligopeptides; Peptide Fragments; Peptides; Peptides, Cyclic; Protein Conformation; Protein Subunits; Receptors, Vitronectin; Recombinant Proteins; Transfection	2002
A novel RGD antagonist that targets both alphavbeta3 and alpha5beta1 induces apoptosis of angiogenic endothelial cells on type I collagen. Vascular pharmacology, 2003, Volume: 40, Issue:2 Topics: Anoikis; Apoptosis; Cell Adhesion; Cell Division; Cell Line; Cell Line, Tumor; Cell Survival; Collagen Type I; Endothelium, Vascular; Extracellular Matrix; Guanidines; Humans; Integrin alpha5beta1; Integrin alphaVbeta3; Intercellular Signaling Peptides and Proteins; Molecular Mimicry; Neovascularization, Pathologic; Oligopeptides; Peptides; Receptors, Immunologic; Sulfonamides; Vitronectin	2003
Effects of echistatin and an RGD peptide on orthodontic tooth movement. Journal of dental research, 2003, Volume: 82, Issue:9 Topics: Amino Acid Sequence; Analysis of Variance; Animals; Bone Remodeling; Cephalometry; Delayed-Action Preparations; Feasibility Studies; Integrins; Intercellular Signaling Peptides and Proteins; Male; Maxilla; Molar; Oligopeptides; Osteoclasts; Peptides; Polyvinyls; Rats; Rats, Sprague-Dawley; Receptors, Immunologic; Receptors, Vitronectin; Tooth Movement Techniques; Viper Venoms	2003
Association of alphavbeta3 integrin expression with the metastatic potential and migratory and chemotactic ability of human osteosarcoma cells. Clinical & experimental metastasis, 2004, Volume: 21, Issue:8 Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Cell Adhesion; Cell Movement; Chemotaxis; Endothelial Cells; Gene Expression Regulation, Neoplastic; Humans; Integrin alphaVbeta3; Intercellular Signaling Peptides and Proteins; Liver; Lung; Lung Neoplasms; Male; Mice; Mice, Nude; Oligopeptides; Osteosarcoma; Peptides; Platelet Aggregation Inhibitors; Receptors, Vitronectin; Tumor Cells, Cultured; Vitronectin	2004
Inhibition of orthodontically induced root resorption with echistatin, an RGD-containing peptide. American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics, 2006, Volume: 129, Issue:2 Topics: Amino Acid Sequence; Animals; Fluorescein-5-isothiocyanate; Image Processing, Computer-Assisted; Immunoenzyme Techniques; Integrin alphaVbeta3; Intercellular Signaling Peptides and Proteins; Male; Microscopy, Fluorescence; Oligopeptides; Osteoclasts; Peptides; Periodontal Ligament; Rats; Rats, Sprague-Dawley; Root Resorption; Tooth Movement Techniques	2006
Novel and selective alpha(v)beta3 receptor peptide antagonist: design, synthesis, and biological behavior. Journal of medicinal chemistry, 2006, Jun-01, Volume: 49, Issue:11 Topics: Cell Adhesion; Crystallography, X-Ray; Drug Design; Humans; Integrin alphaVbeta3; Integrins; Intercellular Signaling Peptides and Proteins; K562 Cells; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Mimicry; Molecular Structure; Oligopeptides; Peptides; Radioligand Assay; Receptors, Vitronectin; Vitronectin	2006
Dual-function probe for PET and near-infrared fluorescence imaging of tumor vasculature. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2007, Volume: 48, Issue:11 Topics: Animals; Cell Line, Tumor; Chelating Agents; Copper Radioisotopes; Heterocyclic Compounds, 1-Ring; Humans; Integrin alphaVbeta3; Intercellular Signaling Peptides and Proteins; Iodine Radioisotopes; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Neovascularization, Pathologic; Oligopeptides; Peptides; Positron-Emission Tomography; Quantum Dots; Radiopharmaceuticals; Spectroscopy, Near-Infrared; Tissue Distribution; Transplantation, Heterologous	2007
Imaging of alpha(v)beta(3) expression by a bifunctional chimeric RGD peptide not cross-reacting with alpha(v)beta(5). Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Aug-15, Volume: 15, Issue:16 Topics: Amino Acid Sequence; Animals; Glioblastoma; Humans; Integrin alphaVbeta3; Intercellular Signaling Peptides and Proteins; Iodine Radioisotopes; K562 Cells; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Oligopeptides; Peptides; Positron-Emission Tomography; Protein Binding; Receptors, Vitronectin; Recombinant Fusion Proteins; Substrate Specificity; Transplantation, Heterologous; Tumor Cells, Cultured	2009
MicroPET imaging of integrin αvβ3 expressing tumors using 89Zr-RGD peptides. Molecular imaging and biology, 2011, Volume: 13, Issue:6 Topics: Animals; Binding, Competitive; Cell Line, Tumor; Humans; Integrin alphaVbeta3; Intercellular Signaling Peptides and Proteins; Iodine Radioisotopes; Ligands; Mice; Mice, Nude; Neoplasms; Oligopeptides; Peptides; Positron-Emission Tomography; Tissue Distribution; Zirconium	2011
Rapid and simple one-step F-18 labeling of peptides. Bioconjugate chemistry, 2011, Mar-16, Volume: 22, Issue:3 Topics: Animals; Binding, Competitive; Cell Line, Tumor; Female; Humans; Integrin alphaVbeta3; Intercellular Signaling Peptides and Proteins; Iodine Radioisotopes; Isotope Labeling; Kinetics; Mice; Oligopeptides; Peptides; Positron-Emission Tomography	2011
Development and validation of competition binding assays for affinity to the extracellular matrix receptors, α(v)β(3) and α(IIb)β(3) integrin. Analytical biochemistry, 2012, Apr-01, Volume: 423, Issue:1 Topics: Binding, Competitive; Biological Assay; Biotinylation; Cell Line, Tumor; Humans; Integrin alphaVbeta3; Intercellular Signaling Peptides and Proteins; Isotope Labeling; Kinetics; Oligopeptides; Peptides; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Reproducibility of Results	2012
Expression in Pichia pastoris and characterization of echistatin, an RGD-containing short disintegrin. Toxicon : official journal of the International Society on Toxinology, 2012, Dec-15, Volume: 60, Issue:8 Topics: Base Sequence; Disintegrins; DNA Primers; Electrophoresis, Polyacrylamide Gel; Intercellular Signaling Peptides and Proteins; Magnetic Resonance Spectroscopy; Mass Spectrometry; Oligopeptides; Peptides; Pichia; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymerase Chain Reaction; Structure-Activity Relationship; Viper Venoms	2012
Mechanical loading promotes mast cell degranulation via RGD-integrin dependent pathways. Journal of biomechanics, 2013, Feb-22, Volume: 46, Issue:4 Topics: Animals; beta-N-Acetylhexosaminidases; Biomechanical Phenomena; Cell Degranulation; Cell Line; Cell Proliferation; Cell Survival; Integrins; Intercellular Signaling Peptides and Proteins; Mast Cells; Oligopeptides; Peptides; Rats; Signal Transduction; Stress, Mechanical; Tensile Strength	2013
A Combined NMR and Computational Approach to Determine the RGDechi-hCit-αv β3 Integrin Recognition Mode in Isolated Cell Membranes. Chemistry (Weinheim an der Bergstrasse, Germany), 2016, Jan-11, Volume: 22, Issue:2 Topics: Cell Membrane; Computers, Molecular; Integrin alphaVbeta3; Intercellular Signaling Peptides and Proteins; Ligands; Magnetic Resonance Spectroscopy; Oligopeptides; Peptides; Receptors, Vitronectin	2016