Compounds > arginine

arginine and u-50488

arginine has been researched along with u-50488 in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (90.00)18.2507
2000's1 (10.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Elliott, K; Inturrisi, CE; Kolesnikov, YA; Minami, N; Pasternak, GW1
Bhargava, HN1
Capasso, A; Carnuccio, R; D'Acquisto, F; Iuvone, T1
Ciszewska, G; Kolesnikov, YA; Pasternak, GW; Pick, CG1
Bhargava, HN; Reddy, PL; Thorat, SN1
Tseng, LF; Xu, JY1
Ellenberger, EA; Gagnon, MJ; Hodges, BL; McDonald, CE; Quock, RM; Ream, JK; Tousman, SA1
Jain, S; Kolesnikov, Y; Pasternak, GW; Wilson, R1
Lin, WB; Lue, WM; Su, MT; Tao, PL1
Haines, DS; Li, JG; Liu-Chen, LY1

Other Studies

10 other study(ies) available for arginine and u-50488

ArticleYear
The NMDA receptor antagonists, LY274614 and MK-801, and the nitric oxide synthase inhibitor, NG-nitro-L-arginine, attenuate analgesic tolerance to the mu-opioid morphine but not to kappa opioids.
    Pain, 1994, Volume: 56, Issue:1

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Amino Acid Oxidoreductases; Analgesics; Animals; Arginine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Tolerance; Injections, Subcutaneous; Isoquinolines; Male; Mice; Morphine; Naloxone; Nitric Oxide Synthase; Nitroarginine; Pyrrolidines; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, kappa; Receptors, Opioid, mu

1994
Nitric oxide synthase inhibition blocks tolerance to the analgesic action of kappa-opiate receptor agonist in the rat.
    Pharmacology, 1994, Volume: 48, Issue:4

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Amino Acid Oxidoreductases; Analgesics; Animals; Arginine; Body Temperature; Body Weight; Drug Tolerance; Male; Nitric Oxide Synthase; omega-N-Methylarginine; Pain Measurement; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa

1994
Opioids inhibit the induction of nitric oxide synthase in J774 macrophages.
    Biochemical and biophysical research communications, 1995, Jul-26, Volume: 212, Issue:3

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Amino Acid Oxidoreductases; Animals; Arginine; Cell Line; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Enzyme Induction; Lipopolysaccharides; Macrophages; Mice; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Nitric Oxide; Nitric Oxide Synthase; Oligopeptides; omega-N-Methylarginine; Pyrrolidines; Receptors, Opioid

1995
Blockade of tolerance to morphine but not to kappa opioids by a nitric oxide synthase inhibitor.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, Jun-01, Volume: 90, Issue:11

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Amino Acid Oxidoreductases; Analgesics; Animals; Arginine; Drug Administration Schedule; Drug Tolerance; Male; Mice; Mice, Inbred Strains; Morphine; Nitric Oxide Synthase; Nitroarginine; Pyrrolidines; Receptors, Opioid, kappa; Substance Withdrawal Syndrome; Time Factors

1993
Evidence for the role of nitric oxide in kappa-opiate tolerance in mice.
    Brain research, 1993, Sep-03, Volume: 621, Issue:1

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Amino Acid Oxidoreductases; Analgesics; Animals; Arginine; Drug Tolerance; Male; Mice; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Pyrrolidines; Receptors, Opioid, kappa

1993
Role of nitric oxide/cyclic GMP in i.c.v. administered beta-endorphin- and (+)-cis-dioxolane-induced antinociception in the mouse.
    European journal of pharmacology, 1994, Sep-12, Volume: 262, Issue:3

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesia; Analgesics; Animals; Arginine; beta-Endorphin; Cyclic GMP; Dioxolanes; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Hemoglobins; Injections, Intraventricular; Male; Methylene Blue; Mice; Mice, Inbred ICR; Morphine; Narcotic Antagonists; Nitric Oxide; Nitroarginine; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Stereoisomerism

1994
Inhibitors of nitric oxide synthesis antagonize nitrous oxide antinociception in mice and rats.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 269, Issue:2

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Arginine; Cerebral Ventricles; Male; Mice; Morphine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrous Oxide; omega-N-Methylarginine; Pyrrolidines; Rats; Rats, Sprague-Dawley

1994
Lack of morphine and enkephalin tolerance in 129/SvEv mice: evidence for a NMDA receptor defect.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 284, Issue:2

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Animals; Arginine; Drug Tolerance; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Mice; Mice, Inbred Strains; Morphine; Nitric Oxide; Nitroprusside; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, delta; Receptors, Opioid, kappa

1998
The role of nitric oxide in the development of morphine tolerance in rat hippocampal slices.
    European journal of pharmacology, 1999, Oct-27, Volume: 383, Issue:2

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Antidiuretic Hormone Receptor Antagonists; Arginine; Arginine Vasopressin; Dizocilpine Maleate; Drug Tolerance; Electrophysiology; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Hippocampus; Male; Morphine; Narcotics; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, kappa; Receptors, Opioid, mu

1999
Agonist-promoted Lys63-linked polyubiquitination of the human kappa-opioid receptor is involved in receptor down-regulation.
    Molecular pharmacology, 2008, Volume: 73, Issue:4

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Amino Acid Sequence; Animals; Arginine; CHO Cells; Cricetinae; Cricetulus; Deubiquitinating Enzyme CYLD; Diprenorphine; Down-Regulation; Endocytosis; Humans; Lysine; Molecular Sequence Data; Mutant Proteins; Mutation; Narcotic Antagonists; Phosphorylation; Polyubiquitin; Protein Structure, Tertiary; Receptors, G-Protein-Coupled; Receptors, Opioid, kappa; Tumor Suppressor Proteins; Ubiquitination

2008