Compounds > arginine

arginine and symmetric dimethylarginine

arginine has been researched along with symmetric dimethylarginine in 402 studies

Research

Studies (402)

TimeframeStudies, this research(%)All Research%
pre-19904 (1.00)18.7374
1990's4 (1.00)18.2507
2000's72 (17.91)29.6817
2010's239 (59.45)24.3611
2020's83 (20.65)2.80

Authors

AuthorsStudies
Epand, RM; Moscarello, MA; Sridhara, SI1
Nissim, I; Pereira, G; Segal, S; Yudkoff, M1
Chang, AC; Lou, MF1
Busch, H; Lischwe, MA; Roberts, KD; Yeoman, LC1
Kim, S; Lee, YJ; Paik, WK; Park, JO; Rawal, N; Whitaker, JN1
Nowicki, M; Ritz, E; Vallance, P1
Dillon, MJ; Frend, A; Goonasekera, CD; Rees, DD; Shah, V; Woolard, P1
Fickling, SA; Holden, DP; Nussey, SS; Whitley, GS1
Cooke, JP1
Bode-Böger, SM; Böger, RH1
Fleck, C; Janz, A; Karge, E; Schweitzer, F; Schwertfeger, M; Stein, G1
Beck, W; Deppisch, RM; Pommer, W; Riedel, E; Schröder, M1
Bode-Böger, SM; Böger, RH; Chowienczyk, PJ; Fisher, I; Jackson, G; McGing, E; Ritter, JM; Walker, HA1
Egashira, K; Ito, A; Muramatsu, K; Narishige, T; Takeshita, A1
Balint, RF; Cooke, JP; Her, JH; Kimoto, M; Stühlinger, MC; Tsao, PS1
Aso, T; Azuma, H; Beppu, M; Goto, M; Obayashi, S1
Deng, HW; Jiang, JL; Li Ns, NS; Li, YJ1
Adimoolam, S; Asagami, T; Cooke, JP; Ito, A; Kimoto, M; Lin, KY; Reaven, GM; Tsao, PS; Tsuji, H1
Kimura, K; Nishio, I; Tsuda, K1
Bonfigli, AR; Coppa, G; Gambini, A; Marra, M; Testa, I; Testa, R1
Azuma, H; Goto, M; Kihara, K; Masuda, H; Sakai, Y; Yano, M1
Brattström, L; Brudin, L; Hultberg, B; Teerlink, T; Wanby, P1
Böger, RH2
Dweik, RA1
Gehring, H; Pahlich, S; Zakaryan, RP1
Blomster, H; Kontkanen, M; Puustjärvi, T; Teräsvirta, M; Uusitalo, H; Valtonen, P1
Holte, AV; Jensen, AL; Kristensen, AT; Moesgaard, SG; Mogensen, T; Mølbak, J; Olsen, LH; Reynolds, AJ; Teerlink, T1
Ayajiki, K; Gemba, M; Okamura, T; Shinozaki, K; Yamamizu, K1
Carru, C; Carta, F; Deiana, L; Gaspa, L; Pinna, A; Sotgia, S; Zinellu, A; Zinellu, E1
Arikan, E; Guldiken, S; Karadag, CH1
Benndorf, RA; Bierend, A; Böger, GI; Böger, RH; Dumbadze, E; Maas, R; Rudolph, TK; Schwedhelm, E1
Bode-Boger, SM; Ertl, T; Martens-Lobenhoffer, J; Sulyok, E; Vida, G2
Grooteman, MP; Nubé, MJ; Teerlink, T; Twisk, JW; Wauters, IM1
Brooks, ER; Miller, A; Price, HE; Smith, FA; Vicente, FB; Wang, S1
Halwachs-Baumann, G; März, W; Meinitzer, A; Puchinger, M; Ribalta, J; Rock, E; Roob, JM; Sundl, I; Winklhofer-Roob, BM1
Fliser, D; Kielstein, JT1
Acikel, C; Caglar, K; Cakir, E; Eyileten, T; Kurt, Y; Oguz, Y; Saglam, M; Sonmez, A; Tasar, M; Vural, A; Yenicesu, M; Yilmaz, MI1
Alfthan, G; Juonala, M; Kähönen, M; Laitinen, T; Marniemi, J; Raitakari, OT; Taittonen, L; Viikari, JS1
Moriatis, M; Naidoo, D; Salonikas, C; Sim, AS; Wang, J; Wang, XL; Wilcken, DE1
Asberg, A; Bigonah, A; Hov, GG; Sagen, E1
Ahn, YM; Ha, EH; Jeon, YJ; Kim, YJ; Lee, HY; Pang, MG; Park, HS; Woo, SY1
Bates, PJ; Casson, LK; Girvan, AC; Pierce, WM; Qian, M; Teng, Y; Thomas, SD1
Boccioletti, V; Cominacini, L; Garbin, U; Manfro, S; Pasini, AF; Stranieri, C1
Carru, C; Deiana, L; Formato, M; Scanu, B; Sotgia, S; Zinellu, A1
Brown, RD; Carlström, M; Edlund, J; Larsson, E; Palm, F; Persson, AE; Sällström, J; Teerlink, T; Wåhlin, N1
Heinonen, S; Heiskanen, N; Juonala, M; Laitinen, T; Lyyra-Laitinen, T; Punnonen, K; Raitakari, OT; Saarelainen, H; Valtonen, P; Vanninen, E; Viikari, JS1
Axelsson, J; Caglar, K; Cakir, E; Carrero, JJ; Eyileten, T; Lindholm, B; Oguz, Y; Qureshi, AR; Saglam, M; Sonmez, A; Stenvinkel, P; Vural, A; Yenicesu, M; Yilmaz, MI1
Beer, JC; Cottin, Y; Duvillard, L; Gambert, P; Guilland, JC; Korandji, C; Lagrost, AC; Lorgis, L; Moreau, D; Rochette, L; Sicard, P; Vergely, C; Zeller, M1
Boeger, RH; Deussen, A; Henle, T; Pexa, A; Schwedhelm, E1
Almer, G; Gasser, R; Gruber, HJ; Horejsi, R; Mangge, H; März, W; Mayer, C; Meinitzer, A; Möller, R; Pilz, S; Truschnig-Wilders, M1
Barbara, JA; Hewitson, CL; Mangoni, AA; McAteer-Carr, B; Whiting, MJ; Woodman, RJ1
Arning, E; Bottiglieri, T; Cooke, JP; Dayal, S; Faraci, FM; Kimoto, M; Lentz, SR; Murry, DJ; Rodionov, RN1
Colaianna, M; Corso, G; D'Apolito, O; Paglia, G; Schiavone, S; Trabace, L; Tricarico, F; Zotti, M1
Corso, G; D'Apolito, O; Garofalo, D; Paglia, G; Tricarico, F1
Iversen, J; Strandgaard, S; Wang, D; Wilcox, CS1
Delfraino, B; Hazen, SL; Hu, B; Klein, AL; Levison, BS; Shrestha, K; Tang, WH; Tong, W; Troughton, RW; Wang, Z1
Carru, C; Deiana, L; Scanu, B; Sotgia, S; Zinellu, A1
Kiefte-de Jong, JC; Nanayakkara, PW; Olthof, MR; Smulders, YM; Stehouwer, CD; Teerlink, T; ter Wee, PM; Twisk, JW; van Guldener, C; van Ittersum, FJ1
Cignarelli, M; Corso, G; D'Apolito, O; Garofalo, D; Lamacchia, O; Paglia, G; Pilotti, A; Tricarico, F1
Billecke, SS; D'Alecy, LG; Gadegbeku, CA; Jamerson, KA; Perlman, RL; Platel, R; Whitesall, SE1
Surdacki, A1
Akyel, A; Biberoglu, G; Cengel, A; Hasanoglu, A; Kocaman, SA; Sahinarslan, A; Timurkaynak, T1
Cortina, B; del Olmo, JA; Lluch, P; Lluch, S; Mauricio, MD; Rodrigo, JM; Segarra, G; Serra, MA; Vila, JM1
Chan, WP; Heresztyn, T; Horowitz, JD; Liberts, EA; Marber, MS; Norman, RJ; Rajendran, S; Saha, M; Willoughby, SR1
Andrzejak, R; Antonowicz-Juchniewicz, J; Chachaj, A; Dzietczenia, J; Kuliczkowski, K; Mazur, G; Szuba, A; Wróbel, T1
Dhondt, A; Glorieux, G; Leybaert, L; Schepers, E; Vanholder, R1
Drescher, FT; Rauwerda, JA; Richir, MC; Siroen, MP; Teerlink, T; van Leeuwen, PA; Wiest, R; Zorger, N1
Egger, G; Holt, DW; Kiechl, S; Lee, T; Mayr, M; Santer, P; Thompson, G; Tsimikas, S; Willeit, J; Xu, Q1
Goniewicz, ML; Sobczak, A; Szoltysek-Boldys, I1
Burnier, M; De Senarclens, O; Dischl, B; Engelberger, RP; Feihl, F; Henry, H; Liaudet, L; Teta, D; Waeber, B1
Brouns, R; De Deyn, PP; Marescau, B; Possemiers, I; Sheorajpanday, R1
Blackwelder, WC; Hazen, SL; Kato, GJ; Machado, RF; Taylor, JG; Wang, Z1
Gray, GA; Leiper, JM; Malaki, M; Miller, AA; Patrizio, M; Sherry, L; Vallance, P; Wallace, AF1
Aucella, F; Boeger, R; Gesualdo, L; Maas, R; Margaglione, M; Schwedhelm, E; Tripepi, G; Vigilante, M; Zoccali, C1
Brennan, DM; Cho, L; Hazen, SL; Tang, WH; Wang, Z1
Blom, H; Carmichael, SL; Finnell, RH; Shaw, GM; Ueland, PM; Vollset, SE; Yang, W1
Bernecker, C; Fauler, G; Fazekas, F; Gruber, HJ; Höbarth, G; Horejsi, R; Lechner, A; Meinitzer, A; Renner, W; Truschnig-Wilders, M; Wallner-Blazek, M; Weiss, S1
Abhary, S; Burdon, KP; Craig, JE; Kasmeridis, N; Kuot, A; Petrovsky, N; Whiting, MJ; Yew, WP1
Ajjan, R; Atzler, D; Böger, RH; Carter, AM; Grant, PJ; Maas, R; Schulze, F; Schwedhelm, E; von Holten, RA1
Dubiel, JS; Dudek, D; Marewicz, E; Pryjma, J; Rakowski, T; Surdacki, A; Szastak, G; Wieczorek-Surdacka, E1
Mangoni, AA1
Baylis, C; Carson, L; Donley, D; Murphy, EC; Neal, W; Yeater, R1
Amin, R; Dalton, RN; Dunger, DB; Marcovecchio, ML; Prevost, AT; Turner, C; Widmer, B1
Francesconi, M; Mittermayer, F; Pleiner, J; Wolzt, M1
Biemond, BJ; Brandjes, DP; Duits, AJ; Landburg, PP; Muskiet, FA; Schnog, JB; Teerlink, T1
Ajtay, Z; Awiszus, F; Bode-Böger, SM; Cziráki, A; Martens-Lobenhoffer, J; Németh, A; Sulyok, E; Szabados, S; Szabó, C1
Guntani, A; Honma, K; Itoh, H; Iwasa, K; Kyuragi, R; Maehara, Y; Matsumoto, T; Ohmine, T; Onohara, T1
Mannen, T; Siomi, H; Siomi, MC1
Artusi, C; Boffa, GM; Ivanova, M; Plebani, M; Zaninotto, M1
Kanazawa, I; Nabika, T; Notsu, Y; Sugimoto, T; Yamaguchi, T; Yano, S2
Gong, W; Huang, Y; Lehmann, R; Li, Z; Liu, H; Wang, JY; Xu, RM1
Bennett, C; Dasarathy, S; Edmison, JM; Kalhan, SC; Kasumov, T; Lopez, R1
Bode-Böger, SM; Bódis, J; Kovács, GL; Martens-Lobenhoffer, J; Sulyok, E; Várnagy, A1
Altun, GD; Aydogdu, N; Gunduz, O; Karadag, H; Kaya, O; Torun, N; Vardar, SA1
Boehm, BO; Drechsler, C; Kielstein, JT; März, W; Meinitzer, A; Pilz, S; Ritz, E; Winkelmann, BR1
Kim, SJ; Lee, SW; Uhm, CS; Yoo, BC1
Gilinsky, MA; Latysheva, TV; Petrakova, GM1
Collin, B; Cottin, Y; Duvillard, L; Goirand, F; Guilland, JC; Korandji, C; Lauzier, B; Moreau, D; Rochette, L; Sicard, P; Vergely, C; Zeller, M1
Bode-Böger, SM; Denecke, A; Kielstein, JT; Martens-Lobenhoffer, J; Schieffer, B; Tutarel, O; Westhoff-Bleck, M1
Blackwell, S; O'Reilly, DS; Reid, D; Talwar, D1
Atzler, D; Benndorf, RA; Böger, RH; Darius, H; Diehm, C; Endres, HG; Lüneburg, N; Maas, R; Schwedhelm, E; Thiem, U; von Stritzky, B1
Beckmann, B; Gutzki, FM; Jordan, J; Tsikas, D1
Dekker, JM; Heine, RJ; Scheffer, PG; Stehouwer, CD; Teerlink, T; van der Zwan, LP1
Ajtay, Z; Alotti, N; Bode-Böger, SM; Cziráki, A; Lenkey, Z; Martens-Lobenhoffer, J; Németh, Á; Sulyok, E; Szabados, S; Szabó, C1
Böger, RH; Schwedhelm, E1
Kirino, Y1
Barry, JA; Hardiman, PJ; Kay, AR; Lakhani, K; Leiper, J1
Belik, J; Grasemann, H; Huang, H; North, ML; Pencharz, P; Rafii, M; Scott, JA; Subbarao, P1
Chen, B; Ji, X; Liang, Y; Wang, Y; Yi, L; Zhang, P; Zhou, Z1
Bucciarelli, T; D'Orazio, N; Felaco, M; Franceschelli, S; Gaeta, R; Grilli, A; Riccioni, G; Speranza, L1
Bode-Böger, SM; Bukowska, A; Ghanem, A; Goette, A; Hammwöhner, M; Klein, HU; Lehmann, HI; Martens-Lobenhoffer, J; Röhl, FW1
Forman, A; Leone, A; Morris, RC; Schmidlin, O; Sebastian, A1
Barreto, DV; Barreto, FC; Eloot, S; Glorieux, G; Liabeuf, S; Massy, Z; Schepers, E; Vanholder, R1
Baek, IH; Chae, JW; Kang, W; Kwon, KI1
Atzler, D; Böger, RH; Glazer, NL; Lüneburg, N; Maas, R; Riederer, U; Schwedhelm, E; Sullivan, LM; Vasan, RS; Xanthakis, V1
Kinugasa, S; Shinohara, K; Wakatsuki, A1
Carlström, M; Fredholm, BB; Gao, X; Patzak, A; Persson, AE; Sällström, J; Scheffer, PG; Sendeski, M; Teerlink, T1
Michaluk-Skutnik, J; Taranta-Janusz, K; Wasilewska, A; Zoch-Zwierz, W1
Anderssohn, M; Böger, RH; Fourie, CM; Glyn, MC; Huisman, HW; Lüneburg, N; Malan, L; Malan, NT; Mels, CM; Schutte, AE; Schutte, R; Smith, W; Van Rooyen, JM1
Hsu, CN; Huang, LT; Lau, YT; Lin, CY; Tain, YL1
Linz, TH; Lunte, SM; Snyder, CM1
Abhary, S; Burdon, KP; Craig, JE; Hewitt, AW; Javadiyan, S; Mills, RA; Straga, T; Whiting, MJ1
Billecke, S; Chen, AF; Craig, T; D'Alecy, LG; Haywood, JR; Hinojosa-Laborde, C; Northcott, CA; Patel, KP1
Stypułkowska, J; Sutuła, M; Taranta-Janusz, K; Wasilewska, A1
Caplin, B; Leiper, J1
Blom, HJ; Castro, R; Jakobs, C; Janssen, MC; Kluijtmans, LA; Rivera, I; Rocha, MS; Smulders, Y; Tavares de Almeida, I; Teerlink, T1
Barassi, A; Ciociola, F; Colpi, GM; Corsi, MM; Dozio, E; Fermo, I; Finati, E; Ghilardi, F; Melzi d'Eril, GV; Paroni, R1
Kokot, F; Kunsdorf-Wnuk, A; Wnuk, Z1
Barth, S; Cassel, C; Deng, W; Fischer, U; Grässer, FA; Gross, H; Hennard, C; Kremmer, E; Leonhardt, H; Mamiani, A; Masouris, I; Moritz, B; Neuenkirchen, N; Noessner, E; Ostareck, D; Ostareck-Lederer, A; Stober-Grässer, U1
Djindjić, N; Ilić, M; Krstić, N; Mladenović, D; Nicković, J; Nicković, V; Nikolić, J1
Bueno-Betí, C; Hermenegildo, C; Laguna-Fernández, A; Lázaro-Franco, M; Monsalve, E; Novella, S; Sanchís, J; Sobrino, A; Tarín, JJ1
Chan, K; Chen, DB; Ehsanipoor, RM; Fitzmaurice, LE; Fortson, W; Liao, WX; Wing, DA1
Dubiel, JS; Fedak, D; Rakowski, T; Surdacki, A; Wieczorek-Surdacka, E; Zawiślak, B1
Basic, J; Cvetkovic, T; Ilic, A; Ljubisavljevic, S; Pavlovic, D; Pavlovic, R; Stojanovic, I; Stukalov, M; Vojinovic, S1
Böger, R; Breitling, LP; Brenner, H; Koenig, W; Maas, R; Rothenbacher, D; Schwedhelm, E; Siegerink, B; Vossen, CY1
Bartáková, V; Bělobrádková, J; Jurajda, M; Kaňková, K; Klepárník, M; Krusová, D; Kuricová, K; Malúšková, D; Mužík, J; Olšovský, J; Pácal, L; Pavlík, T; Rehořová, J; Stěpánková, S; Svojanovský, J; Tanhäuserová, V; Tomandl, J1
Cavalca, V; De Metrio, M; Marenzi, G; Moltrasio, M; Porro, B; Rubino, M; Squellerio, I; Tremoli, E; Veglia, F1
Anderssohn, M; Böger, RH; Frey, N; Lüneburg, N; Lutz, M; Rosenberg, M; Schwedhelm, E; Zugck, C1
Bucciarelli, T; Felaco, M; Franceschelli, S; Gallina, S; Patruno, A; Pesce, M; Riccioni, G; Speranza, L1
Attia, JR; Carru, C; Mangoni, AA; McEvoy, M; Zinellu, A1
Linz, TH; Lunte, SM1
He, H; Jiang, H; Li, X; Liu, X; Liu, Y; Wang, H; Wang, S; Yuan, L; Zhang, W1
Balestrieri, ML; Castaldo, D; Cautela, D; Giovane, A; Servillo, L1
Brykner, R; Cwynar-Zając, Ł; Dzięgiel, P; Ewa Chlebda-Sieragowska, E; Fereniec-Gołębiewska, L; Gomułkiewicz, A; Kwiatkowska, J; Merwid-Ląd, A; Pieśniewska, M; Sozański, T; Szeląg, A; Szuba, A; Trocha, M1
Betz, B; Böger, RH; Kniepert, J; Kress, T; Möller-Ehrlich, K; Sauvant, C; Schneider, R; Schwedhelm, E; Wanner, C1
Bichat, F; Chagnon, A; Cottin, Y; Guilland, JC; Korandji, C; Lorin, J; Rochette, L; Touzery, C; Vergely, C; Zeller, M1
Davids, M; Teerlink, T1
Agho, K; Attia, J; Carru, C; Hancock, S; Inder, K; Kelly, B; Mangoni, AA; McEvoy, MA; Peel, R; Schofield, P; Smith, W; Soiza, RL; Zinellu, A1
Bruensing, J; Buendgens, L; Dückers, H; Koch, A; Kunze, J; Luedde, T; Matthes, M; Tacke, F; Trautwein, C; Weiskirchen, R1
Cavalca, V; Chiorino, E; Crisci, M; Eligini, S; Garlaschè, A; Giovannardi, M; Lualdi, A; Porro, B; Squellerio, I; Tremoli, E; Veglia, F; Werba, JP1
Boeger, RH; Hamer, M; Lambert, GW; Malan, L; Malan, NT; Reimann, M; Schlaich, MP; Ziemssen, T1
Alexiou, P; Honda, S; Kirino, Y; Maragkakis, M; Mourelatos, Z; Murali, R; Ohtaki, A1
Deloach, S; Huan, Y; Kapoor, S; Meyers, K; Ommen, E; Townsend, RR1
Anderssohn, M; Atzler, D; Ayers, CR; Böger, RH; de Lemos, JA; Gore, MO; Grant, PJ; Khera, A; Lüneburg, N; McGuire, DK; Schwedhelm, E1
Bloch, KE; Hefti, U; Hess, T; Huber, AR; Maggiorini, M; Merz, TM; Pichler Hefti, J; Risch, L; Schoch, OD; Sonntag, D; Turk, AJ; Weinberger, KM1
Cvetkovic, TP; Djordjevic, VM; Paunovic, GJ; Pavlovic, DD; Stefanovic, NZ; Stojanovic, DR; Stojanovic, IR; Velickovic-Radovanovic, RM1
Agho, K; Attia, J; Mangoni, AA; McEvoy, M; Peel, R; Schofield, P; Smith, W; Soiza, RL1
Bogavac-Stanojevic, N; Dopsaj, V; Giga, V; Jelic-Ivanovic, Z; Kotur-Stevuljevic, J; Memon, L; Simic-Ogrizovic, S; Spasic, S; Spasojevic-Kalimanovska, V1
Ajjan, R; Anderssohn, M; Böger, RH; Grant, PJ; Lüneburg, N; McLachlan, S; Price, JF; Robertson, C; Schwedhelm, E; Strachan, MW; Williamson, RM1
Dopsaj, V; Giga, V; Jelic-Ivanovic, Z; Kotur-Stevuljevic, J; Memon, L; Simic-Ogrizovic, S; Spasic, S; Spasojevic-Kalimanovska, V; Stanojevic, NB1
Korzeniecka-Kozerska, A; Taranta-Janusz, K; Tenderenda-Banasiuk, E; Wasilewska, A1
De Gennaro Colonna, V; Ferrario, P; Lavanga, V; Pascale, V; Pascale, W; Sansone, V1
Chen, J; Fong, KW; Gong, Z; Han, X; Hebert, M; Li, Y; Ma, W; Songyang, Z; Tang, M1
Baranyi, A; Kapfhammer, HP; Meinitzer, A; Putz-Bankuti, C; Rothenhäusler, HB; Stauber, R1
Caceres, TB; Chen, J; Chen, X; Gong, Q; Hevel, JM; Liu, L; Peng, J; Shi, Y; Teng, M; Wang, C; Wang, J; Wu, J; Zhang, Z; Zhu, Y; Zuo, X1
Bucciarelli, T; D'Orazio, N; Gallina, S; Riccioni, G; Scotti, L; Speranza, L; Speziale, G1
Bode-Böger, SM; Fliser, D; Kielstein, JT; Schepers, E; Speer, T1
Atzler, D; Böger, RH; Dörr, M; Friedrich, N; Kroemer, HK; Nauck, M; Schwedhelm, E; Völker, U; Völzke, H; Wallaschofski, H1
Charakida, M; Chinetti-Gbaguidi, G; Colin, S; Deanfield, JE; Fliser, D; Hettrich, I; Landmesser, U; Long, D; McLoughlin, E; O'Neill, F; Rohrer, L; Shanahan, CM; Shroff, R; Speer, T; Staels, B; Zewinger, S1
Huang, YH; Kuo, HC; Lee, CP; Tain, YL1
Atzler, D; Böger, RH; Friedrich, N; Ittermann, T; Nauck, M; Schwedhelm, E1
Bammens, B; Claes, KJ; de Loor, H; Evenepoel, P; Kuypers, DR; Lerut, E; Meijers, B; Naesens, M; Sprangers, B; Vanrenterghem, Y1
Abedini, S; Dahle, DO; Fellström, B; Holdaas, H; Holme, I; Jardine, A; März, W; Midtvedt, K; Mjøen, G; Pihlstrøm, H; Pilz, S1
Adachi, T; Hakuno, D; Kimura, K; Kujiraoka, T; Masaki, N; Miyazaki, K; Namba, T; Shiraishi, Y; Toya, T; Yada, H1
Gerstoft, J; Kvale, D; Manner, IW; Nielsen, SD; Os, I; Pedersen, KK; Seljeflot, I; Trøseid, M1
Döner, U; Düngen, HD; Duvinage, A; Edelmann, F; Gaksch, M; Gelbrich, G; Kienreich, K; Kunde, J; März, W; Meinitzer, A; Pieske, B; Pilz, S; Schmidt, A; Stahrenberg, R; Tomaschitz, A; Wachter, R1
Anderssohn, M; Benjamin, EJ; Bernges, I; Blankenberg, S; Böger, RH; Carter, AM; Chen, MH; Erdmann, J; Fornage, M; Gieger, C; Glazer, NL; Grant, PJ; Heckbert, SR; Ikram, MA; Illig, T; Kittel, A; König, IR; König, J; Lackner, K; Lieb, W; Loley, C; Longstreth, WT; Lüneburg, N; Lunetta, KL; Maas, R; Meisinger, C; Munzel, T; Ojeda, FM; Psaty, BM; Schillert, A; Schunkert, H; Schwedhelm, E; Seshadri, S; Smith, N; Sticht, H; Sullivan, LM; Vasan, RS; Wang, TJ; Wichmann, HE; Wiggins, KL; Wild, PS; Xanthakis, V; Zeller, T; Ziegler, A1
Feliers, D; Gorin, Y; Kasinath, BS; Lee, DY1
Bode-Böger, SM; Martens-Lobenhoffer, J1
Hall, JA; Jewell, DE; Obare, E; Yerramilli, M; Yu, S1
Delafontaine, P; Egan, P; Fernandez, C; Giles, TD; Kandavar, R; Kim, C; Roffidal, LE; Sander, GE; Sukhanov, S; Velaga, S1
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Anfinsen, KP; Harjen, HJ; Lund, H; Moldal, ER; Negard, T; Nicolaysen, TV; Rørtveit, R; Sævik, BK; Zimmer, KE1
Boretti, FS; Casado Díaz, JI; Fracassi, F; Reusch, CE; Sieber-Ruckstuhl, NS1
Cai, J; Chen, L; Gao, Y; Gonzalez, FJ; Guo, X; Jiang, J; Krausz, KW; Liu, W; Luo, Y; Qu, A; Sun, L; Takahashi, S; Tang, W; Wang, Y; Xie, C; Yang, S; Yang, Y1
Balfanz, P; Böger, R; Dahl, E; Dreher, M; Hannemann, J; Hartmann, B; Marx, N; Müller-Wieland, D; Schwedhelm, E; Ule, J1
Asıl, M; Kebapçılar, L; Korkmaz, H; Öztürk, B; Temel, T1
Csecsei, P; Csiszar, B; Halmosi, R; Kenyeres, P; Marton, Z; Molnar, T; Nagy, L; Riba, J; Sandor, B; Toth, K1
Brandão, J; Guthrie, A; Mota, SM1
Couto, CG; Coyne, M; Drake, C; Murphy, R1
Grauer, GF; Hegarty, E; Mack, RM; McCrann, DJ; Michael, HT1
Attia, JR; Hancock, SJ; Holliday, E; Mangoni, AA; McEvoy, MA; Oldmeadow, C; Peel, R; Smith, WT; Talley, NJ; Walker, MM1
Abdel-Raof, YM; Elgazzar, YMY; Ghanem, MM; Helal, MAY; Kandiel, MMM1
Atzler, D; Böger, RH; Duncan, MS; Hannemann, J; Maas, R; Moser, C; Schwedhelm, E; Vasan, RS; Xanthakis, V; Yola, IM1
Gough, RL; McGovern, KF1
Biswas, S; Dunn, C; Himmel, L; Kohnken, R; LeRoy, B; Logan, M; Peterson, R1
Lamglait, B; Raulic, J; Vergneau-Grosset, C1
Bozorgmanesh, R; Coyne, M; Fletcher, C; Hegarty, E; Mack, R; Murphy, R; Slovis, N; Snyder, J; Thornton, J1
Bosch, A; Fromm, MF; Gemeinhardt, A; Gessner, A; Kannenkeril, D; Maas, R; Mayr, A; Schmieder, RE; Staerk, C1
Beckmann, B; Brinkmann, F; Dillenhöfer, S; Frank, M; Hamelmann, E; Hanusch, B; Holtmann, M; Jöckel, KH; Koerner-Rettberg, C; Langrock, C; Legenbauer, T; Lücke, T; Maasjosthusmann, P; Reinehr, T; Sinningen, K; Tsikas, D1
Coyne, MJ; Cushing, AC; Gauger, V; Murphy, R; Obare, E; Szlosek, D1
Coyne, MJ; Cross, J; Drake, C; Hamlin, DM; Leissinger, MK; Mack, R; McCrann, DJ; Murphy, RE; Schultze, AE; Strong-Townsend, M; Yerramilli, M1
Clements, C; Mack, R; Michael, H; Szlosek, D1
Dizdarevic, AM; Eyileten, C; Gasecka, A; Jarosz-Popek, J; Lang, IM; Nowak, A; Postula, M; Siller-Matula, JM; Ufnal, M; Wolska, M1
Bonnitcha, P; Fitzpatrick, M; Ireland, A; Koay, YC; Nguyen, VL; O'Sullivan, J; Sullivan, D1
Coyne, MJ; Cross, J; Drake, C; Mack, R; McCrann, DJ; Murphy, RE; Schultze, AE; Strong-Townsend, M1
Coyne, MJ; Drake, C; Kincaid, D; McCrann, DJ1
Loane, SC; McCallum, KE; Thomson, JM; Williams, TL1
Duncan, JS; Gupta, S; Kruger, WD; Kurimchak, AM; Lee, HO; Tang, B; Wang, L1
Hidayat, R; Hustrini, NM; Pradwipa, RY; Shatri, H1
Güney, Z; Günhan, M; Kurgan, S; Mammadov, C; Önder, C; Serdar, MA1
Doğan, Ö; Haşimi, A; Serdar, CC; Serdar, MA1
Drapała, A; Samborowska, E; Szlęzak, D; Ufnal, M; Wróbel, M1
Bernhardt Rovaris, I; da Cruz Schaefer, G; de Faria Valle, S; de Mattos Brose, M; Herrera Becerra, JR; Peixoto da Silva Mello, F; Poletto Ferreira, M; Schneck Simão, B; Vieira Amorim da Costa, F1
Coyne, M; Drake, C; Kane, LP; Keller, KA; Murphy, R; Obare, E1
Böger, R; Hannemann, J; Laing, A; Middleton, B; Schwedhelm, E; Skene, DJ1
Bahls, M; Böger, RH; Dörr, M; Friedrich, N; Ittermann, T; Schwedhelm, E; Winkler, MS1

Reviews

27 review(s) available for arginine and symmetric dimethylarginine

ArticleYear
Does ADMA cause endothelial dysfunction?
    Arteriosclerosis, thrombosis, and vascular biology, 2000, Volume: 20, Issue:9

    Topics: Amidohydrolases; Arginine; Arteriosclerosis; Endothelium, Vascular; Homeostasis; Humans; Hydrolases; Neovascularization, Physiologic; Nitric Oxide; Nitric Oxide Synthase

2000
Asymmetric dimethylarginine, derangements of the endothelial nitric oxide synthase pathway, and cardiovascular diseases.
    Seminars in thrombosis and hemostasis, 2000, Volume: 26, Issue:5

    Topics: Animals; Arginine; Arteriosclerosis; Cardiovascular Diseases; Endothelium, Vascular; Humans; Nitric Oxide Synthase

2000
Association of asymmetric dimethylarginine and endothelial dysfunction.
    Clinical chemistry and laboratory medicine, 2003, Volume: 41, Issue:11

    Topics: Animals; Arginine; Cardiovascular Diseases; Endothelium, Vascular; Humans; Nitric Oxide Synthase

2003
Asymmetric dimethylarginine (ADMA): a novel risk marker in cardiovascular medicine and beyond.
    Annals of medicine, 2006, Volume: 38, Issue:2

    Topics: Arginine; Arteriosclerosis; Biomarkers; Cardiovascular Diseases; Clinical Trials as Topic; Endothelium, Vascular; Female; Humans; Hyperthyroidism; Insulin Resistance; Liver Failure; Male; Metabolic Syndrome; Nitric Oxide; Nitric Oxide Synthase; Pre-Eclampsia; Pregnancy; Risk Factors; Stereoisomerism

2006
The lung in the balance: arginine, methylated arginines, and nitric oxide.
    American journal of physiology. Lung cellular and molecular physiology, 2007, Volume: 292, Issue:1

    Topics: Animals; Arginine; Humans; Lung; Methylation; Models, Biological; Nitric Oxide; omega-N-Methylarginine; Protein-Arginine N-Methyltransferases

2007
Protein arginine methylation: Cellular functions and methods of analysis.
    Biochimica et biophysica acta, 2006, Volume: 1764, Issue:12

    Topics: Arginine; DNA Repair; F-Box Proteins; Humans; Mass Spectrometry; Methyltransferases; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases; Proteomics; RNA Processing, Post-Transcriptional; S-Adenosylmethionine; Signal Transduction; Transcription, Genetic

2006
L-arginine analogs--inactive markers or active agents in atherogenesis?
    Cardiovascular & hematological agents in medicinal chemistry, 2008, Volume: 6, Issue:4

    Topics: Arginine; Atherosclerosis; Biomarkers; Coronary Disease; Endothelium, Vascular; Humans; Inflammation; Nitric Oxide; Oxidative Stress

2008
The emerging role of symmetric dimethylarginine in vascular disease.
    Advances in clinical chemistry, 2009, Volume: 48

    Topics: Arginine; Cardiovascular Diseases; Homeostasis; Humans; Nitric Oxide; Nitric Oxide Synthase Type III; Renal Insufficiency

2009
How does the royal family of Tudor rule the PIWI-interacting RNA pathway?
    Genes & development, 2010, Apr-01, Volume: 24, Issue:7

    Topics: Animals; Arginine; Argonaute Proteins; Drosophila Proteins; Humans; Membrane Transport Proteins; Protein Methyltransferases; Protein Processing, Post-Translational; Proteins; RNA-Induced Silencing Complex; RNA, Small Interfering

2010
The role of asymmetric and symmetric dimethylarginines in renal disease.
    Nature reviews. Nephrology, 2011, Volume: 7, Issue:5

    Topics: Arginine; Humans; Kidney; Renal Insufficiency, Chronic; Risk Factors

2011
[Role of arginine methylation in the Piwi-interacting RNA pathway].
    Seikagaku. The Journal of Japanese Biochemical Society, 2011, Volume: 83, Issue:4

    Topics: Animals; Arginine; Argonaute Proteins; Drosophila Proteins; Humans; Membrane Transport Proteins; Methylation; Protein Binding; Protein Methyltransferases; Protein-Arginine N-Methyltransferases; RNA-Induced Silencing Complex; RNA, Small Interfering

2011
Endogenous nitric oxide synthase inhibitors in the biology of disease: markers, mediators, and regulators?
    Arteriosclerosis, thrombosis, and vascular biology, 2012, Volume: 32, Issue:6

    Topics: Amidohydrolases; Animals; Arginine; Binding Sites; Binding, Competitive; Biomarkers; Cardiovascular Agents; Cardiovascular Diseases; Catalytic Domain; Enzyme Inhibitors; Humans; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine

2012
Dimethylarginines ADMA and SDMA: the real water-soluble small toxins?
    Seminars in nephrology, 2014, Volume: 34, Issue:2

    Topics: Arginine; Biomarkers; Cardiovascular Diseases; Humans; Kidney Diseases; Water

2014
Endothelial Dysfunction in Renal Failure: Current Update.
    Current medicinal chemistry, 2016, Volume: 23, Issue:19

    Topics: Arginine; Endothelium, Vascular; Humans; Nitric Oxide; Oxidative Stress; Renal Insufficiency; Uremia; Vascular Cell Adhesion Molecule-1; Vitamin D Deficiency

2016
Symmetric Dimethylarginine: Improving the Diagnosis and Staging of Chronic Kidney Disease in Small Animals.
    The Veterinary clinics of North America. Small animal practice, 2016, Volume: 46, Issue:6

    Topics: Animals; Arginine; Biomarkers; Cat Diseases; Cats; Dog Diseases; Dogs; Renal Insufficiency, Chronic

2016
Asymmetric and Symmetric Dimethylarginine as Risk Markers for Total Mortality and Cardiovascular Outcomes: A Systematic Review and Meta-Analysis of Prospective Studies.
    PloS one, 2016, Volume: 11, Issue:11

    Topics: Arginine; Biomarkers; Cardiovascular Diseases; Humans; Prospective Studies; Risk Factors

2016
Metabolomics for clinical use and research in chronic kidney disease.
    Nature reviews. Nephrology, 2017, Volume: 13, Issue:5

    Topics: Arginine; Biomarkers; Biomedical Research; Carnitine; Diabetes Mellitus; Humans; Lipid Metabolism; Metabolomics; Oxidative Stress; Renal Insufficiency, Chronic

2017
Toxic Dimethylarginines: Asymmetric  Dimethylarginine (ADMA) and Symmetric  Dimethylarginine (SDMA).
    Toxins, 2017, 03-06, Volume: 9, Issue:3

    Topics: Animals; Arginine; Humans; Toxins, Biological

2017
AGXT2: An unnegligible aminotransferase in cardiovascular and urinary systems.
    Journal of molecular and cellular cardiology, 2017, Volume: 113

    Topics: Animals; Arginine; Cardiovascular Diseases; Cardiovascular System; Humans; Kidney Diseases; Transaminases

2017
HDL in CKD-The Devil Is in the Detail.
    Journal of the American Society of Nephrology : JASN, 2018, Volume: 29, Issue:5

    Topics: Advanced Oxidation Protein Products; Apolipoprotein A-V; Apolipoprotein L1; Arginine; Cardiovascular Diseases; Cholesterol; Cholesterol, HDL; Glomerular Filtration Rate; Humans; Lipid Metabolism; MicroRNAs; Renal Insufficiency, Chronic; Serum Amyloid A Protein

2018
Genetic regulation of dimethylarginines and endothelial dysfunction in rheumatoid arthritis.
    Amino acids, 2019, Volume: 51, Issue:7

    Topics: Arginine; Arthritis, Rheumatoid; Atherosclerosis; Biomarkers; Cardiovascular Diseases; Endothelium, Vascular; Humans; Inflammation; Nitric Oxide; Nitric Oxide Synthase; Polymorphism, Single Nucleotide; Transaminases

2019
Asymmetric (ADMA) and Symmetric (SDMA) Dimethylarginines in Chronic Kidney Disease: A Clinical Approach.
    International journal of molecular sciences, 2019, Jul-26, Volume: 20, Issue:15

    Topics: Aging; Animals; Arginine; Cardiovascular Diseases; Endothelium, Vascular; Humans; Metabolic Networks and Pathways; Molecular Targeted Therapy; Prognosis; Renal Dialysis; Renal Insufficiency, Chronic

2019
Asymmetric and symmetric dimethylarginine concentration as an indicator of cardiovascular diseases in rheumatoid arthritis patients: a systematic review and meta-analysis of case-control studies.
    Clinical rheumatology, 2020, Volume: 39, Issue:1

    Topics: Arginine; Arthritis, Rheumatoid; Biomarkers; Cardiovascular Diseases; Case-Control Studies; Comorbidity; Endothelium, Vascular; Humans; Risk Factors

2020
The Second Life of Methylarginines as Cardiovascular Targets.
    International journal of molecular sciences, 2019, Sep-17, Volume: 20, Issue:18

    Topics: Amidohydrolases; Animals; Arginine; Biological Transport; Biomarkers; Cardiovascular Diseases; Cardiovascular System; Disease Susceptibility; Energy Metabolism; Humans; Molecular Targeted Therapy

2019
Protein Arginine Methyltransferases in Cardiovascular and Neuronal Function.
    Molecular neurobiology, 2020, Volume: 57, Issue:3

    Topics: Animals; Arginine; Cardiovascular Diseases; Cardiovascular System; Humans; Methylation; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases

2020
Arginine Derivatives in Cerebrovascular Diseases: Mechanisms and Clinical Implications.
    International journal of molecular sciences, 2020, Mar-05, Volume: 21, Issue:5

    Topics: Arginine; Biomarkers; Cerebrovascular Disorders; Endothelium, Vascular; Homoarginine; Humans; Nitric Oxide Synthase; Risk Factors

2020
Symmetrical Dimethylarginine: Evaluating Chronic Kidney Disease in the Era of Multiple Kidney Biomarkers.
    The Veterinary clinics of North America. Small animal practice, 2022, Volume: 52, Issue:3

    Topics: Animals; Arginine; Biomarkers; Cat Diseases; Cats; Creatinine; Dog Diseases; Dogs; Female; Kidney; Male; Renal Insufficiency, Chronic

2022

Trials

26 trial(s) available for arginine and symmetric dimethylarginine

ArticleYear
Endothelium-dependent vasodilation is independent of the plasma L-arginine/ADMA ratio in men with stable angina: lack of effect of oral L-arginine on endothelial function, oxidative stress and exercise performance.
    Journal of the American College of Cardiology, 2001, Volume: 38, Issue:2

    Topics: Administration, Oral; Angina Pectoris; Arginine; Dinoprost; Double-Blind Method; Endothelium, Vascular; Exercise; Exercise Test; F2-Isoprostanes; Forearm; Heart Rate; Humans; Injections, Intra-Arterial; Male; Middle Aged; Oxidative Stress; Regional Blood Flow; Vasodilation

2001
Renin-angiotensin system is involved in the mechanism of increased serum asymmetric dimethylarginine in essential hypertension.
    Japanese circulation journal, 2001, Volume: 65, Issue:9

    Topics: Adrenergic beta-Antagonists; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Arginine; Bisoprolol; Blood Pressure; Endothelium, Vascular; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Nitric Oxide Synthase; Perindopril; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; von Willebrand Factor

2001
Asymmetric dimethylarginine determines the improvement of endothelium-dependent vasodilation by simvastatin: Effect of combination with oral L-arginine.
    Journal of the American College of Cardiology, 2007, Jun-12, Volume: 49, Issue:23

    Topics: Aged; Aged, 80 and over; Arginine; C-Reactive Protein; Drug Therapy, Combination; Endothelium, Vascular; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipoproteins; Male; Middle Aged; Nitric Oxide Synthase Type III; Simvastatin; Vasodilation

2007
Plasma dimethylarginine levels in chronic hemodialysis patients are independent of the type of dialyzer applied.
    Blood purification, 2007, Volume: 25, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Arginine; beta 2-Microglobulin; Biocompatible Materials; Complement C3a; Cross-Over Studies; Equipment Design; Female; Humans; Kidney Failure, Chronic; Male; Membranes, Artificial; Middle Aged; Nitric Oxide; Prospective Studies; Renal Dialysis

2007
Improving proteinuria, endothelial functions and asymmetric dimethylarginine levels in chronic kidney disease: ramipril versus valsartan.
    Blood purification, 2007, Volume: 25, Issue:4

    Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Arginine; Biomarkers; Blood Glucose; C-Reactive Protein; Female; Glomerular Filtration Rate; Hemorheology; Humans; Insulin Resistance; Kidney Failure, Chronic; Lipids; Male; Middle Aged; Proteinuria; Ramipril; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan; Vasodilation

2007
Randomized placebo-controlled trial assessing a treatment strategy consisting of pravastatin, vitamin E, and homocysteine lowering on plasma asymmetric dimethylarginine concentration in mild to moderate CKD.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2009, Volume: 53, Issue:1

    Topics: Adult; Aged; Anticholesteremic Agents; Arginine; Carotid Arteries; Chronic Disease; Creatinine; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Kidney Diseases; Lipoproteins, LDL; Male; Middle Aged; Pravastatin; Vitamin B 12; Vitamin B 6; Vitamin E

2009
Effects of an exercise intervention using Dance Dance Revolution on endothelial function and other risk factors in overweight children.
    International journal of pediatric obesity : IJPO : an official journal of the International Association for the Study of Obesity, 2009, Volume: 4, Issue:4

    Topics: Arginine; Biomarkers; Blood Glucose; Blood Pressure; Body Height; Body Mass Index; Body Weight; Brachial Artery; Child; Dance Therapy; Endothelium, Vascular; Exercise Therapy; Female; Humans; Inflammation Mediators; Insulin; Lipids; Male; Nitrates; Nitrites; Overweight; Oxygen Consumption; Patient Compliance; Physical Fitness; Risk Factors; Time Factors; Treatment Outcome; Ultrasonography; Vasodilation; Video Games

2009
Treatment with alpha-lipoic acid reduces asymmetric dimethylarginine in patients with type 2 diabetes mellitus.
    Translational research : the journal of laboratory and clinical medicine, 2010, Volume: 155, Issue:1

    Topics: Arginine; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Humans; Male; Middle Aged; Thioctic Acid

2010
The efficacy of oral beraprost sodium, a prostaglandin I2 analogue, for treating intermittent claudication in patients with arteriosclerosis obliterans.
    International angiology : a journal of the International Union of Angiology, 2010, Volume: 29, Issue:2 Suppl

    Topics: Administration, Oral; Aged; Ankle Brachial Index; Arginine; Arteriosclerosis Obliterans; Biomarkers; Endothelin-1; Epoprostenol; Exercise Test; Exercise Tolerance; Humans; Intermittent Claudication; Platelet Aggregation Inhibitors; Prospective Studies; Time Factors; Treatment Outcome; Vasodilation; Vasodilator Agents; Walking

2010
Symmetrical and asymmetrical dimethylarginine as predictors for mortality in patients referred for coronary angiography: the Ludwigshafen Risk and Cardiovascular Health study.
    Clinical chemistry, 2011, Volume: 57, Issue:1

    Topics: Aged; Arginine; Biomarkers; Cardiovascular Diseases; Coronary Angiography; Coronary Disease; Female; Humans; Linear Models; Male; Middle Aged; Mortality; Predictive Value of Tests; Prognosis; Renal Insufficiency; Risk Factors

2011
Salt sensitivity in blacks: evidence that the initial pressor effect of NaCl involves inhibition of vasodilatation by asymmetrical dimethylarginine.
    Hypertension (Dallas, Tex. : 1979), 2011, Volume: 58, Issue:3

    Topics: Adult; Arginine; Black or African American; Blood Pressure; Dose-Response Relationship, Drug; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Sodium Chloride, Dietary; Time Factors; Vascular Resistance; Vasodilation

2011
The biological evaluation of ADMA/SDMA and eNOS in patients with ACHF.
    Frontiers in bioscience (Elite edition), 2013, 01-01, Volume: 5, Issue:2

    Topics: Adult; Aged; Alanine Transaminase; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Arginine; Aspartate Aminotransferases; Blotting, Western; Chromatography, High Pressure Liquid; Digoxin; Diuretics; Echocardiography; Electron Transport Complex IV; Female; Heart Failure; Humans; Kidney Function Tests; Leukocytes, Mononuclear; Male; Middle Aged; Nitric Oxide Synthase Type III; Oxygen

2013
Symmetric dimethylarginine as predictor of graft loss and all-cause mortality in renal transplant recipients.
    Transplantation, 2014, Dec-15, Volume: 98, Issue:11

    Topics: Adult; Aged; Arginine; Biomarkers; Fatty Acids, Monounsaturated; Female; Fluvastatin; Follow-Up Studies; Graft Rejection; Humans; Indoles; Kidney; Kidney Transplantation; Male; Middle Aged; Multivariate Analysis; Proportional Hazards Models; Renal Insufficiency; Risk Factors; Time Factors; Transplant Recipients; Treatment Outcome

2014
Digital plethysmography and arginine metabolism in prehypertension: effect of nebivolol therapy.
    Journal of clinical hypertension (Greenwich, Conn.), 2015, Volume: 17, Issue:1

    Topics: Adult; Antihypertensive Agents; Arginine; Benzopyrans; Blood Pressure; Citrulline; Endothelium, Vascular; Ethanolamines; Female; Humans; Male; Middle Aged; Nebivolol; Nitric Oxide; Plethysmography; Prehypertension; Prospective Studies; Regional Blood Flow

2015
Symmetric dimethylarginine (SDMA) serum levels in rheumatoid arthritis: correlations with insulin resistance and disease activity scores.
    Amino acids, 2015, Volume: 47, Issue:9

    Topics: Adult; Aged; Arginine; Arthritis, Rheumatoid; Atherosclerosis; Cohort Studies; Endothelium, Vascular; Female; Humans; Insulin Resistance; Male; Middle Aged; Nitric Oxide

2015
Changes in plasma levels of asymmetric dimethylarginine, symmetric dimethylarginine, and arginine after a single dose of vardenafil in patients with pulmonary hypertension.
    Vascular pharmacology, 2015, Volume: 73

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Arginine; Atrial Function, Right; Atrial Pressure; Biomarkers; Cardiac Output; Female; Humans; Hypertension, Pulmonary; Male; Middle Aged; Phosphodiesterase 5 Inhibitors; Time Factors; Treatment Outcome; Vardenafil Dihydrochloride; Vasodilator Agents

2015
Asymmetric and Symmetric Dimethylarginine and Sympathetic Nerve Traffic after Renal Denervation in Patients with Resistant Hypertension.
    Clinical journal of the American Society of Nephrology : CJASN, 2015, Sep-04, Volume: 10, Issue:9

    Topics: Aged; Arginine; Blood Pressure; Drug Resistance; Female; Heart Rate; Humans; Hypertension; Longitudinal Studies; Male; Middle Aged; Muscle, Skeletal; Sympathectomy; Sympathetic Nervous System

2015
Positive Impact of Nutritional Interventions on Serum Symmetric Dimethylarginine and Creatinine Concentrations in Client-Owned Geriatric Dogs.
    PloS one, 2016, Volume: 11, Issue:4

    Topics: Age Factors; Animal Feed; Animals; Arginine; Biomarkers; Blood Proteins; Body Weight; Creatinine; Diet; Dogs; Feeding Behavior; Female; Glomerular Filtration Rate; Kidney Function Tests; Male; Ownership; Prospective Studies

2016
In vivo microvascular and macrovascular endothelial function is not associated with circulating dimethylarginines in patients with rheumatoid arthritis: a prospective analysis of the DRACCO cohort.
    Scandinavian journal of clinical and laboratory investigation, 2016, Volume: 76, Issue:4

    Topics: Aged; Arginine; Arthritis, Rheumatoid; Atherosclerosis; Carotid Artery Diseases; Carotid Intima-Media Thickness; Endothelium, Vascular; Female; Humans; Immunoenzyme Techniques; Microvessels; Middle Aged; Models, Biological; Prospective Studies; Pulse Wave Analysis; Ultrasonography

2016
Effect of the transdermal low-level laser therapy on endothelial function.
    Lasers in medical science, 2016, Volume: 31, Issue:7

    Topics: Adult; Angiostatins; Arginine; Female; Fibroblast Growth Factors; Glutathione; Humans; Lasers, Semiconductor; Low-Level Light Therapy; Male; Nitric Oxide; Vascular Endothelial Growth Factor A

2016
Nutritional Interventions that Slow the Age-Associated Decline in Renal Function in a Canine Geriatric Model for Elderly Humans.
    The journal of nutrition, health & aging, 2016, Volume: 20, Issue:10

    Topics: Absorptiometry, Photon; Aged; Aging; Animals; Arginine; Biomarkers; Body Weight; Carnitine; Cross-Sectional Studies; Diet; Dietary Proteins; Dietary Supplements; Disease Models, Animal; Dogs; Female; Fish Oils; Fruit; Geriatric Assessment; Glomerular Filtration Rate; Humans; Kidney; Male; Thioctic Acid; Vegetables

2016
Effects of Vitamin D3 on asymmetric- and symmetric dimethylarginine in arterial hypertension.
    The Journal of steroid biochemistry and molecular biology, 2018, Volume: 175

    Topics: Aged; Analysis of Variance; Arginine; Blood Pressure; Cholecalciferol; Dietary Supplements; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Vitamin D; Vitamin D Deficiency

2018
Serum Asymmetric and Symmetric Dimethylarginine and Morbidity and Mortality in Hemodialysis Patients.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2017, Volume: 70, Issue:1

    Topics: Arginine; Cardiovascular Diseases; Female; Humans; Male; Middle Aged; Morbidity; Prospective Studies; Renal Dialysis

2017
Hemodiafiltration is associated with reduced inflammation, oxidative stress and improved endothelial risk profile compared to high-flux hemodialysis in children.
    PloS one, 2018, Volume: 13, Issue:6

    Topics: Adolescent; Arginine; Biomarkers; Child; Female; Hemodiafiltration; Humans; Inflammation; Male; Oxidative Stress; Prospective Studies; Treatment Outcome

2018
A high-protein meal does not improve blood pressure or vasoactive biomarker responses to acute exercise in humans.
    Nutrition research (New York, N.Y.), 2020, Volume: 81

    Topics: Adult; Arginine; Biomarkers; Blood Pressure; Cross-Over Studies; Dietary Fats; Dietary Proteins; Double-Blind Method; Exercise; Female; Humans; Male; Meals; Postprandial Period

2020
Effects of treatment with SGLT-2 inhibitors on arginine-related cardiovascular and renal biomarkers.
    Cardiovascular diabetology, 2022, 01-06, Volume: 21, Issue:1

    Topics: Arginine; Benzhydryl Compounds; Biomarkers; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glucosides; Glycated Hemoglobin; Humans; Male; Middle Aged; Predictive Value of Tests; Prospective Studies; Sodium-Glucose Transporter 2 Inhibitors; Time Factors; Treatment Outcome

2022

Other Studies

349 other study(ies) available for arginine and symmetric dimethylarginine

ArticleYear
Phospholipid vesicle aggregation induced by human myelin basic protein.
    Neurochemical research, 1984, Volume: 9, Issue:2

    Topics: Arginine; Centrifugation, Density Gradient; Humans; Lipid Bilayers; Liposomes; Multiple Sclerosis; Myelin Basic Protein; Phosphatidylcholines; Protein Binding; Structure-Activity Relationship

1984
Urinary excretion of dimethylarginines in premature infants.
    Biochemical medicine, 1984, Volume: 32, Issue:2

    Topics: Adolescent; Adult; Aging; Arginine; Body Weight; Child; Child, Preschool; Diet; Gestational Age; Humans; Infant; Infant, Newborn; Infant, Premature; Male; Methylhistidines; Muscle Proteins; Nitrogen; Proteins

1984
Dimethylarginines in human amniotic fluid.
    Clinical chemistry, 1982, Volume: 28, Issue:3

    Topics: Amniotic Fluid; Arginine; Female; Humans; Pregnancy

1982
Nucleolar specific acidic phosphoprotein C23 is highly methylated.
    The Journal of biological chemistry, 1982, Dec-25, Volume: 257, Issue:24

    Topics: Amino Acids; Animals; Arginine; Cell Nucleolus; Liver Neoplasms, Experimental; Methylation; Molecular Weight; Phosphoproteins; Rats

1982
Urinary excretion of NG-dimethylarginines in multiple sclerosis patients: preliminary observations.
    Journal of the neurological sciences, 1995, Volume: 129, Issue:2

    Topics: Arginine; Case-Control Studies; Chromatography, High Pressure Liquid; Humans; Multiple Sclerosis; Reference Values; Sensitivity and Specificity

1995
The effect of malnutrition on cardiovascular mortality in dialysis patients: is L-arginine the answer?
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1994, Volume: 9, Issue:2

    Topics: Arginine; Arteriosclerosis; Cardiovascular Diseases; Humans; Models, Biological; Nitric Oxide; Nutrition Disorders; Renal Dialysis

1994
Nitric oxide synthase inhibitors and hypertension in children and adolescents.
    Journal of hypertension, 1997, Volume: 15, Issue:8

    Topics: Adolescent; Animals; Arginine; Child; Endothelium, Vascular; Enzyme Inhibitors; Female; Glomerular Filtration Rate; Humans; Hypertension; Hypertension, Renal; Hypertension, Renovascular; In Vitro Techniques; Male; Mice; Muscle Contraction; Nitric Oxide Synthase; omega-N-Methylarginine; Phenylephrine; Renin; Vasoconstrictor Agents

1997
Plasma concentrations of asymmetric dimethylarginine, a natural inhibitor of nitric oxide synthase, in normal pregnancy and preeclampsia.
    American journal of obstetrics and gynecology, 1998, Volume: 178, Issue:3

    Topics: Adult; Arginine; Blood Pressure; Female; Gestational Age; Humans; Nitric Oxide Synthase; Pre-Eclampsia; Pregnancy; Regression Analysis

1998
Serum concentrations of asymmetric (ADMA) and symmetric (SDMA) dimethylarginine in renal failure patients.
    Kidney international. Supplement, 2001, Volume: 78

    Topics: Adult; Aged; Amino Acids; Arginine; Blood Pressure; Case-Control Studies; Creatinine; Female; Humans; Kidney Failure, Chronic; Kidney Transplantation; Male; Middle Aged; Renal Dialysis

2001
Increased reduction of dimethylarginines and lowered interdialytic blood pressure by the use of biocompatible membranes.
    Kidney international. Supplement, 2001, Volume: 78

    Topics: Adult; Aged; Arginine; beta 2-Microglobulin; Biocompatible Materials; Blood Pressure; Diabetic Nephropathies; Female; Hematocrit; Hemodiafiltration; Hemoglobins; Humans; Kidney Failure, Chronic; Kidneys, Artificial; Male; Membranes, Artificial; Middle Aged; Renal Dialysis; Urea

2001
Homocysteine impairs the nitric oxide synthase pathway: role of asymmetric dimethylarginine.
    Circulation, 2001, Nov-20, Volume: 104, Issue:21

    Topics: Amidohydrolases; Animals; Aorta; Arginine; Arteriosclerosis; Cattle; Cell Line; Culture Techniques; Endothelium, Vascular; Homocysteine; Hydrolases; Hyperhomocysteinemia; Kinetics; Methionine; Nitric Oxide; Nitric Oxide Synthase; Recombinant Fusion Proteins; Signal Transduction

2001
Endogenous nitric oxide synthase inhibitors in endothelial cells, endothelin-1 within the vessel wall, and intimal hyperplasia in perimenopausal human uterine arteries.
    Journal of cardiovascular pharmacology, 2002, Volume: 39, Issue:2

    Topics: Adult; Arginine; Arteries; Chromatography, High Pressure Liquid; Climacteric; Cyclic GMP; Endothelin-1; Endothelium, Vascular; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Female; Humans; Hyperplasia; In Vitro Techniques; Middle Aged; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Tunica Intima; Tunica Media; Uterus

2002
Probucol preserves endothelial function by reduction of the endogenous nitric oxide synthase inhibitor level.
    British journal of pharmacology, 2002, Volume: 135, Issue:5

    Topics: Animals; Aorta, Thoracic; Arginine; Endothelium, Vascular; Enzyme Inhibitors; Lipoproteins, LDL; Male; Malondialdehyde; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Probucol; Rats; Rats, Sprague-Dawley; Vasodilation

2002
Impaired nitric oxide synthase pathway in diabetes mellitus: role of asymmetric dimethylarginine and dimethylarginine dimethylaminohydrolase.
    Circulation, 2002, Aug-20, Volume: 106, Issue:8

    Topics: Amidohydrolases; Animals; Antioxidants; Aorta; Arginine; Cell Line; Cells, Cultured; Cyclic GMP; Diabetes Mellitus, Experimental; Endothelium, Vascular; Enzyme Inhibitors; Glucose; Humans; Male; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Oxidative Stress; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Superoxide Dismutase

2002
Leptin improves membrane fluidity of erythrocytes in humans via a nitric oxide-dependent mechanism--an electron paramagnetic resonance investigation.
    Biochemical and biophysical research communications, 2002, Sep-27, Volume: 297, Issue:3

    Topics: Arginine; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Erythrocyte Membrane; Humans; In Vitro Techniques; Kinetics; Leptin; Membrane Fluidity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Reference Values

2002
High-performance liquid chromatographic assay of asymmetric dimethylarginine, symmetric dimethylarginine, and arginine in human plasma by derivatization with naphthalene-2,3-dicarboxaldehyde.
    Analytical biochemistry, 2003, Jul-01, Volume: 318, Issue:1

    Topics: Arginine; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Naphthalenes; Reference Standards; Reproducibility of Results; Spectrometry, Fluorescence; Stereoisomerism

2003
Roles of accumulated endogenous nitric oxide synthase inhibitors and decreased nitric oxide synthase activity for impaired trigonal relaxation with ischemia.
    The Journal of urology, 2003, Volume: 170, Issue:4 Pt 1

    Topics: Animals; Arginine; Electric Stimulation; Ischemia; Male; Muscle Relaxation; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Rabbits; Urinary Bladder

2003
Asymmetric dimethylarginine and total homocysteine in plasma after oral methionine loading.
    Scandinavian journal of clinical and laboratory investigation, 2003, Volume: 63, Issue:5

    Topics: Administration, Oral; Adult; Arginine; Homocysteine; Humans; Male; Methionine; Middle Aged; Time Factors

2003
Asymmetric dimethylarginine is not elevated in exfoliation syndrome but symmetric dimethylarginine is related to exfoliative glaucoma.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2007, Volume: 245, Issue:2

    Topics: Aged; Arginine; Chromatography, High Pressure Liquid; Cross-Sectional Studies; Exfoliation Syndrome; Female; Glaucoma; Homocysteine; Humans; Male; Oxidative Stress; Prospective Studies

2007
Effects of breed, gender, exercise and white-coat effect on markers of endothelial function in dogs.
    Research in veterinary science, 2007, Volume: 82, Issue:3

    Topics: Alaska; Animals; Arginine; Biomarkers; Color; Dogs; Endothelium; Enzyme Inhibitors; Female; Gene Expression Regulation; Hair; Male; Nitric Oxide; Physical Conditioning, Animal; Sex Characteristics; von Willebrand Factor

2007
Oral administration of both tetrahydrobiopterin and L-arginine prevents endothelial dysfunction in rats with chronic renal failure.
    Journal of cardiovascular pharmacology, 2007, Volume: 49, Issue:3

    Topics: Acetylcholine; Administration, Oral; Animals; Aorta; Arginine; Biopterins; Blood Pressure; Calcimycin; Drug Synergism; Drug Therapy, Combination; Endothelium, Vascular; Kidney Failure, Chronic; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Superoxides

2007
High-throughput CZE-UV determination of arginine and dimethylated arginines in human plasma.
    Electrophoresis, 2007, Volume: 28, Issue:12

    Topics: Arginine; Electrophoresis, Capillary; Homoarginine; Humans; Plasma; Spectrophotometry, Ultraviolet

2007
Asymmetric dimethylarginine levels in thyroid diseases.
    Journal of endocrinological investigation, 2007, Volume: 30, Issue:3

    Topics: Adult; Arginine; Biomarkers; Female; Humans; Hyperthyroidism; Hypothyroidism; Male; Middle Aged; Thyroid Diseases

2007
Plasma asymmetric dimethylarginine concentration during the perinatal period.
    Neonatology, 2007, Volume: 92, Issue:1

    Topics: Adult; Arginine; Blood Circulation; Endothelium, Vascular; Female; Humans; Infant, Newborn; Nitric Oxide; Nitric Oxide Synthase; Placental Circulation; Postpartum Period; Pregnancy; Pregnancy Trimester, Third

2007
Measurement of arginine derivatives in pediatric patients with chronic kidney disease using high-performance liquid chromatography-tandem mass spectrometry.
    Clinical chemistry and laboratory medicine, 2007, Volume: 45, Issue:10

    Topics: Adolescent; Arginine; Biomarkers; Case-Control Studies; Child; Chromatography, High Pressure Liquid; Female; Humans; Kidney Failure, Chronic; Male; Reproducibility of Results; Sensitivity and Specificity; Siblings; Tandem Mass Spectrometry; Time Factors

2007
Reference values for plasma concentrations of asymmetrical dimethylarginine (ADMA) and other arginine metabolites in men after validation of a chromatographic method.
    Clinica chimica acta; international journal of clinical chemistry, 2007, Volume: 384, Issue:1-2

    Topics: Adult; Aged; Arginine; Chromatography, High Pressure Liquid; Homoarginine; Humans; Male; Middle Aged

2007
Lowering asymmetric dimethylarginine--a new mechanism mediating the renoprotective effects of renin-angiotensin system inhibitors in proteinuric patients?
    Blood purification, 2007, Volume: 25, Issue:4

    Topics: Amidohydrolases; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Biomarkers; Hemorheology; Humans; Kidney; Kidney Failure, Chronic; Proteinuria; Rats; Renin-Angiotensin System; Vasodilation

2007
Brachial artery flow-mediated dilation and asymmetrical dimethylarginine in the cardiovascular risk in young Finns study.
    Circulation, 2007, Sep-18, Volume: 116, Issue:12

    Topics: Adult; Arginine; Biomarkers; Brachial Artery; Cardiovascular Diseases; Cross-Sectional Studies; Endothelium, Vascular; Female; Finland; Follow-Up Studies; Hemorheology; Humans; Male; Nitric Oxide Synthase Type III; Oxidative Stress; Risk; Sampling Studies; Vasodilation

2007
Relations between markers of renal function, coronary risk factors and the occurrence and severity of coronary artery disease.
    Atherosclerosis, 2008, Volume: 197, Issue:2

    Topics: Age Factors; Aged; Arginine; Biomarkers; Cohort Studies; Coronary Artery Disease; Cystatin C; Cystatins; Female; Glomerular Filtration Rate; Homocysteine; Humans; Male; Middle Aged; Renal Insufficiency; Risk Factors

2008
Health-associated reference values for arginine, asymmetric dimethylarginine (ADMA) and symmetric dimethylarginine (SDMA) measured with high-performance liquid chromatography.
    Scandinavian journal of clinical and laboratory investigation, 2007, Volume: 67, Issue:8

    Topics: Adult; Age Distribution; Aged; Arginine; Chromatography, High Pressure Liquid; Female; Health; Humans; Male; Middle Aged; Reference Values

2007
Prenatal increased asymmetric dimethylarginine is associated with placental heat-shock protein 70 and lectin-like oxidized low-density lipoprotein receptor-1 expression.
    Archives of medical research, 2007, Volume: 38, Issue:8

    Topics: Arginine; Blotting, Western; Female; HSP70 Heat-Shock Proteins; Humans; Immunohistochemistry; Nitric Oxide; Placenta; Pregnancy; Scavenger Receptors, Class E; Term Birth

2007
AS1411 alters the localization of a complex containing protein arginine methyltransferase 5 and nucleolin.
    Cancer research, 2007, Nov-01, Volume: 67, Issue:21

    Topics: Aptamers, Nucleotide; Arginine; Cell Cycle; Cell Line, Tumor; Cell Nucleus; Cytoplasm; Gene Expression Regulation; Humans; Male; Nucleolin; Oligodeoxyribonucleotides; Phosphoproteins; Protein Methyltransferases; Protein Transport; Protein-Arginine N-Methyltransferases; RNA-Binding Proteins

2007
Nebivolol reduces asymmetric dimethylarginine in endothelial cells by increasing dimethylarginine dimethylaminohydrolase 2 (DDAH2) expression and activity.
    Pharmacological research, 2007, Volume: 56, Issue:6

    Topics: Adrenergic beta-Antagonists; Amidohydrolases; Antihypertensive Agents; Arginine; Atenolol; Benzopyrans; Cell Line; Endothelial Cells; Ethanolamines; Female; Humans; Male; Nebivolol; Nitric Oxide Synthase Type III; RNA, Messenger

2007
Assessment of protein-incorporated arginine methylation in biological specimens by CZE UV-detection.
    Electrophoresis, 2007, Volume: 28, Issue:23

    Topics: Arginine; Blood Proteins; Cells, Cultured; Electrophoresis, Capillary; Endothelium, Vascular; Feasibility Studies; Humans; Methylation; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases; Proteins; Sensitivity and Specificity; Specimen Handling; Spectrophotometry, Ultraviolet; Umbilical Veins

2007
Role of nitric oxide deficiency in the development of hypertension in hydronephrotic animals.
    American journal of physiology. Renal physiology, 2008, Volume: 294, Issue:2

    Topics: Animals; Arginine; Blood Pressure; Disease Models, Animal; Diuresis; Enzyme Inhibitors; Hydronephrosis; Hypertension; Indazoles; Kidney; Kidney Cortex; Kidney Tubules, Proximal; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Potassium; Rats; Rats, Sprague-Dawley; Sodium; Sodium Chloride, Dietary; Ureteral Obstruction

2008
Subtle changes in ADMA and l-arginine concentrations in normal pregnancies are unlikely to account for pregnancy-related increased flow-mediated dilatation.
    Clinical physiology and functional imaging, 2008, Volume: 28, Issue:2

    Topics: Adult; Arginine; Blood Flow Velocity; Blood Glucose; Brachial Artery; Case-Control Studies; Cross-Sectional Studies; Endothelium, Vascular; Female; Finland; Humans; Lipids; Pregnancy; Pregnancy Complications, Cardiovascular; Prospective Studies; Statistics, Nonparametric; Ultrasonography; Vasodilation

2008
ADMA levels correlate with proteinuria, secondary amyloidosis, and endothelial dysfunction.
    Journal of the American Society of Nephrology : JASN, 2008, Volume: 19, Issue:2

    Topics: Adult; Amyloidosis; Arginine; Chronic Disease; Endothelium; Female; Glomerulonephritis; Humans; Male; Multivariate Analysis; Predictive Value of Tests; Proteinuria; Risk Factors

2008
Impact of asymmetric dimethylarginine on mortality after acute myocardial infarction.
    Arteriosclerosis, thrombosis, and vascular biology, 2008, Volume: 28, Issue:5

    Topics: Aged; Aged, 80 and over; Arginine; Biomarkers; Cohort Studies; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myocardial Infarction; Predictive Value of Tests; Prognosis; Prospective Studies; Regression Analysis

2008
Effects of moderate hyperhomocysteinaemia induced by 4 weeks methionine-enriched diet on metabolite profile and mesenteric artery function in rats.
    The British journal of nutrition, 2008, Volume: 99, Issue:5

    Topics: Animals; Arginine; Biomarkers; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Diet; Homocysteine; Hyperhomocysteinemia; Male; Mesenteric Arteries; Methionine; Rats; Rats, Wistar; Vasodilation

2008
Asymmetric dimethylarginine (ADMA) is tightly correlated with growth in juveniles without correlations to obesity related disorders.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2008, Volume: 116, Issue:9

    Topics: Adolescent; Alkaline Phosphatase; Arginine; Atherosclerosis; Blood Pressure; Body Mass Index; Child; Female; Growth; Humans; Male; Obesity; Reference Values; Regression Analysis; Young Adult

2008
Symmetric dimethylarginine is an independent predictor of intradialytic hypotension.
    American journal of hypertension, 2008, Volume: 21, Issue:8

    Topics: Aged; Arginine; Biomarkers; Blood Pressure; Female; Humans; Hypotension; Kidney Failure, Chronic; Male; Middle Aged; omega-N-Methylarginine; Predictive Value of Tests; Renal Dialysis

2008
Tissue-specific downregulation of dimethylarginine dimethylaminohydrolase in hyperhomocysteinemia.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 295, Issue:2

    Topics: Amidohydrolases; Animals; Arginine; Carotid Arteries; Cell Line; Cystathionine beta-Synthase; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Endothelial Cells; Endothelium, Vascular; Folic Acid; Gene Expression Regulation, Enzymologic; Homocysteine; Hyperhomocysteinemia; Liver; Methionine; Methylation; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; RNA, Messenger; Vasodilation; Vasodilator Agents

2008
Determination of dimethylarginine levels in rats using HILIC-MS/MS: an in vivo microdialysis study.
    Journal of separation science, 2008, Volume: 31, Issue:13

    Topics: Animals; Arginine; Chromatography, Liquid; Enzyme Inhibitors; Microdialysis; Nitric Oxide Synthase; Prefrontal Cortex; Rats; Rats, Wistar; Reference Standards; Tandem Mass Spectrometry

2008
Evaluation of mobile phase, ion pairing, and temperature influence on an HILIC-MS/MS method for L-arginine and its dimethylated derivatives detection.
    Journal of separation science, 2008, Volume: 31, Issue:13

    Topics: Acrylonitrile; Arginine; Blood Chemical Analysis; Chromatography, Liquid; Indicators and Reagents; Reference Standards; Tandem Mass Spectrometry; Temperature; Trifluoroacetic Acid

2008
Asymmetric dimethylarginine, oxidative stress, and vascular nitric oxide synthase in essential hypertension.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2009, Volume: 296, Issue:2

    Topics: Adult; Arginine; Blood Pressure; Buttocks; Endothelium-Dependent Relaxing Factors; Female; Humans; Hypertension; Linoleic Acids; Lipid Peroxidation; Male; Microvessels; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Subcutaneous Tissue; Up-Regulation; Vasodilation; Young Adult

2009
Differential effects of arginine methylation on diastolic dysfunction and disease progression in patients with chronic systolic heart failure.
    European heart journal, 2008, Volume: 29, Issue:20

    Topics: Arginine; Biomarkers; Chronic Disease; Diastole; Disease Progression; Echocardiography, Doppler; Electrocardiography; Female; Heart Failure, Systolic; Humans; Male; Methylation; Middle Aged; Natriuretic Peptides; Nitric Oxide; Predictive Value of Tests; Prospective Studies; Renal Insufficiency; Tandem Mass Spectrometry; Treatment Outcome; Ventricular Remodeling

2008
Determination of protein-incorporated methylated arginine reference values in healthy subjects whole blood and evaluation of factors affecting protein methylation.
    Clinical biochemistry, 2008, Volume: 41, Issue:14-15

    Topics: Adult; Aged; Aged, 80 and over; Arginine; Female; Health; Humans; Male; Methylation; Middle Aged; omega-N-Methylarginine; Proteins; Reference Values; Regression Analysis

2008
Development and validation of a fast quantitative method for plasma dimethylarginines analysis using liquid chromatography-tandem mass spectrometry.
    Clinical biochemistry, 2008, Volume: 41, Issue:16-17

    Topics: Arginine; Calibration; Chromatography, Liquid; Humans; Quality Control; Reproducibility of Results; Tandem Mass Spectrometry

2008
Blood content of asymmetric dimethylarginine: new insights into its dysregulation in renal disease.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2009, Volume: 24, Issue:2

    Topics: Adult; Arginine; Biomarkers; Case-Control Studies; Erythrocytes; Female; Humans; Hypertension; Kidney Failure, Chronic; Male; Middle Aged; Peptide Hydrolases; Plasma

2009
Asymmetric dimethylarginine and coronary collateral vessel development.
    Coronary artery disease, 2008, Volume: 19, Issue:7

    Topics: Adult; Aged; Arginine; Biomarkers; Collateral Circulation; Coronary Angiography; Coronary Circulation; Coronary Stenosis; Female; Humans; Male; Middle Aged; Odds Ratio

2008
Unchanged plasma levels of dimethylarginines and nitric oxide in chronic hepatitis C.
    Scandinavian journal of gastroenterology, 2009, Volume: 44, Issue:2

    Topics: Adult; Antiviral Agents; Arginine; Case-Control Studies; Female; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Nitric Oxide; Polyethylene Glycols; Recombinant Proteins; Ribavirin

2009
Polycystic ovary syndrome is associated with severe platelet and endothelial dysfunction in both obese and lean subjects.
    Atherosclerosis, 2009, Volume: 204, Issue:2

    Topics: Adenosine Diphosphate; Adult; Albuterol; Arginine; Body Composition; C-Reactive Protein; Cohort Studies; Endothelial Cells; Endothelium, Vascular; Female; Humans; Inflammation Mediators; Malondialdehyde; Nitric Oxide; Nitric Oxide Donors; Nitroglycerin; Nitroprusside; Obesity; Oxidative Stress; Platelet Aggregation; Platelet Function Tests; Polycystic Ovary Syndrome; Stem Cells; Time Factors; Vasodilator Agents

2009
Asymmetric dimethylarginine in hematological malignancies: a preliminary study.
    Leukemia & lymphoma, 2008, Volume: 49, Issue:12

    Topics: Adult; Aged; Arginine; Biomarkers, Tumor; Case-Control Studies; Female; Hematologic Neoplasms; Humans; Male; Middle Aged; Prognosis; Risk Factors

2008
Role of symmetric dimethylarginine in vascular damage by increasing ROS via store-operated calcium influx in monocytes.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2009, Volume: 24, Issue:5

    Topics: Angiotensin-Converting Enzyme Inhibitors; Anticoagulants; Arginine; Calcium; Calcium Channel Blockers; Calcium Channels; Captopril; Edetic Acid; Enzyme Inhibitors; Humans; Imidazoles; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Reactive Oxygen Species; Respiratory Burst; Thapsigargin; Vascular Diseases

2009
Transjugular intrahepatic portosystemic shunt-placement increases arginine/asymmetric dimethylarginine ratio in cirrhotic patients.
    World journal of gastroenterology, 2008, Dec-21, Volume: 14, Issue:47

    Topics: Adult; Aged; Aged, 80 and over; Arginine; Female; Follow-Up Studies; Humans; Hypertension, Portal; Liver; Liver Cirrhosis; Male; Middle Aged; Nitric Oxide; Portasystemic Shunt, Transjugular Intrahepatic

2008
Asymmetric and symmetric dimethylarginines are of similar predictive value for cardiovascular risk in the general population.
    Atherosclerosis, 2009, Volume: 205, Issue:1

    Topics: Adult; Aged; Arginine; Cardiovascular Diseases; Cohort Studies; Female; Humans; Male; Mass Spectrometry; Middle Aged; Nitric Oxide; Proportional Hazards Models; Prospective Studies; Risk

2009
ADMA and SDMA levels in healthy men exposed to tobacco smoke.
    Atherosclerosis, 2009, Volume: 205, Issue:2

    Topics: Adolescent; Adult; Arginine; Cerebrovascular Disorders; Coronary Vessels; Humans; Male; Middle Aged; Nitric Oxide Synthase; Regression Analysis; Risk Factors; Smoking; Tobacco Smoke Pollution

2009
Haemodialysis acutely reduces the plasma levels of ADMA without reversing impaired NO-dependent vasodilation.
    Clinical science (London, England : 1979), 2009, Aug-24, Volume: 117, Issue:8

    Topics: Aged; Aged, 80 and over; Arginine; Case-Control Studies; Endothelium, Vascular; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Nitric Oxide; Regional Blood Flow; Renal Dialysis; Skin; Skin Temperature; Vasodilation

2009
Dimethylarginine levels in cerebrospinal fluid of hyperacute ischemic stroke patients are associated with stroke severity.
    Neurochemical research, 2009, Volume: 34, Issue:9

    Topics: Aged; Arginine; Brain Ischemia; Female; Humans; Ischemic Attack, Transient; Male; Middle Aged; Stroke

2009
Endogenous nitric oxide synthase inhibitors in sickle cell disease: abnormal levels and correlations with pulmonary hypertension, desaturation, haemolysis, organ dysfunction and death.
    British journal of haematology, 2009, Volume: 145, Issue:4

    Topics: Anemia, Sickle Cell; Arginine; Case-Control Studies; Citrulline; Follow-Up Studies; Hemolysis; Humans; Hypertension, Pulmonary; Kidney Diseases; Linear Models; Nitric Oxide Synthase; omega-N-Methylarginine; Oxygen; Proportional Hazards Models; Risk; Survival Rate

2009
Immunolocalisation and activity of DDAH I and II in the heart and modification post-myocardial infarction.
    Acta histochemica, 2010, Volume: 112, Issue:5

    Topics: Amidohydrolases; Animals; Aorta; Arginine; Disease Models, Animal; Endocardium; Heart Ventricles; Male; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Protein-Arginine N-Methyltransferases; Rats; Rats, Wistar

2010
Methylarginines and mortality in patients with end stage renal disease: a prospective cohort study.
    Atherosclerosis, 2009, Volume: 207, Issue:2

    Topics: Adult; Aged; Arginine; Biomarkers; Female; Hemoglobins; Humans; Kaplan-Meier Estimate; Kidney Failure, Chronic; Male; Methylation; Middle Aged; Predictive Value of Tests; Proportional Hazards Models; Prospective Studies; Renal Dialysis; Risk Assessment; Risk Factors

2009
Targeted metabolomic evaluation of arginine methylation and cardiovascular risks: potential mechanisms beyond nitric oxide synthase inhibition.
    Arteriosclerosis, thrombosis, and vascular biology, 2009, Volume: 29, Issue:9

    Topics: Aged; Arginine; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Citrulline; Coronary Artery Disease; Creatinine; Female; Humans; Lysine; Male; Metabolomics; Methylation; Middle Aged; Nitric Oxide Synthase; Odds Ratio; omega-N-Methylarginine; Ornithine; Prognosis; Prospective Studies; Protein Processing, Post-Translational; Risk Assessment; Risk Factors; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Time Factors

2009
Nested case-control study of one-carbon metabolites in mid-pregnancy and risks of cleft lip with and without cleft palate.
    Pediatric research, 2009, Volume: 66, Issue:5

    Topics: Adult; Arginine; Carbon; Case-Control Studies; Cleft Lip; Cleft Palate; Dietary Supplements; Female; Folic Acid; Humans; Maternal Age; Nutritional Sciences; Odds Ratio; Pregnancy; Vitamins

2009
Increased nitric oxide stress is associated with migraine.
    Cephalalgia : an international journal of headache, 2010, Volume: 30, Issue:4

    Topics: Adult; Aged; Amidohydrolases; Arginine; Female; Humans; Male; Migraine with Aura; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Polymorphism, Genetic; Risk Factors; Stress, Physiological

2010
Diabetic retinopathy is associated with elevated serum asymmetric and symmetric dimethylarginines.
    Diabetes care, 2009, Volume: 32, Issue:11

    Topics: Anthracenes; Arginine; Biomarkers; Blindness; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Humans; Models, Molecular; Multivariate Analysis; Propane

2009
Symmetric dimethylarginine predicts all-cause mortality following ischemic stroke.
    Atherosclerosis, 2010, Volume: 208, Issue:2

    Topics: Aged; Aged, 80 and over; Albumins; Arginine; beta-Thromboglobulin; C-Reactive Protein; Endothelium, Vascular; Enzyme Inhibitors; Female; Glomerular Filtration Rate; Humans; Ischemia; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Risk Factors; Stroke; von Willebrand Factor

2010
Synergistic effects of asymmetrical dimethyl-L-arginine accumulation and endothelial progenitor cell deficiency on renal function decline during a 2-year follow-up in stable angina.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2010, Volume: 25, Issue:8

    Topics: Adult; Aged; Angina Pectoris; Angioplasty, Balloon, Coronary; Antigens, CD34; Arginine; Biomarkers; Cell Count; Endothelial Cells; Follow-Up Studies; Glomerular Filtration Rate; Humans; Kidney; Leukocytes; Male; Middle Aged; Multivariate Analysis; Stem Cells

2010
Symmetric dimethylarginine, an endogenous marker of glomerular filtration rate, and the risk for microalbuminuria in young people with type 1 diabetes.
    Archives of disease in childhood, 2010, Volume: 95, Issue:2

    Topics: Adolescent; Age of Onset; Albuminuria; Arginine; Biomarkers; Child; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Disease Progression; England; Epidemiologic Methods; Female; Glomerular Filtration Rate; Humans; Male; Prognosis

2010
Plasma asymmetric dimethylarginine concentrations in sickle cell disease are related to the hemolytic phenotype.
    Blood cells, molecules & diseases, 2010, Apr-15, Volume: 44, Issue:4

    Topics: Adult; Albuminuria; Anemia, Sickle Cell; Arginine; beta-Thalassemia; Cholelithiasis; Female; Hemolysis; Humans; Hypertension, Pulmonary; Leg Ulcer; Male; Middle Aged; Nitric Oxide; Osteonecrosis; Phenotype; Priapism; Retinal Diseases; Sickle Cell Trait; Young Adult

2010
Effects of stent implementation on plasma levels of asymmetric dimethylarginine in patients with or without ST-segment elevation acute myocardial infarction.
    International journal of molecular medicine, 2010, Volume: 25, Issue:4

    Topics: Angioplasty, Balloon, Coronary; Arginine; Case-Control Studies; Coronary Angiography; Female; Humans; Male; Methylation; Middle Aged; Myocardial Infarction; Ornithine; Stents; Ultrasonography

2010
HPLC determination of plasma dimethylarginines: method validation and preliminary clinical application.
    Clinica chimica acta; international journal of clinical chemistry, 2010, Nov-11, Volume: 411, Issue:21-22

    Topics: Adolescent; Adult; Aged; Arginine; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Creatine; Endothelium, Vascular; Female; Glomerular Filtration Rate; Humans; Kidney Function Tests; Male; Middle Aged; Renal Insufficiency, Chronic; Young Adult

2010
Relationships between dimethylarginine and the presence of vertebral fractures in type 2 diabetes mellitus.
    Clinical endocrinology, 2010, Volume: 73, Issue:4

    Topics: Adult; Aged; Arginine; Bone Density; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Risk Factors; Spinal Fractures

2010
Structural basis for methylarginine-dependent recognition of Aubergine by Tudor.
    Genes & development, 2010, Sep-01, Volume: 24, Issue:17

    Topics: Amino Acid Sequence; Animals; Arginine; Conserved Sequence; Drosophila melanogaster; Drosophila Proteins; Germ Cells; Membrane Transport Proteins; Models, Molecular; Molecular Sequence Data; Peptide Initiation Factors; Protein Binding; Protein Structure, Quaternary; Protein Structure, Tertiary; Sequence Alignment

2010
Plasma levels of asymmetric dimethylarginine in patients with biopsy-proven nonalcoholic fatty liver disease.
    Metabolism: clinical and experimental, 2011, Volume: 60, Issue:6

    Topics: Adult; Arginine; Biopsy; Blood Glucose; Chromatography, High Pressure Liquid; Fatty Liver; Female; Glomerular Filtration Rate; Humans; Insulin Resistance; Liver; Male; Middle Aged

2011
Negative association of L-arginine methylation products with oocyte numbers.
    Human reproduction (Oxford, England), 2010, Volume: 25, Issue:12

    Topics: Adult; Arginine; Female; Fertilization in Vitro; Follicular Fluid; Humans; Methylation; Oocytes; Ovulation Induction

2010
The alteration of asymmetric dimetilarginine (ADMA) levels in cardiac and gastrocnemius muscles following radioactive iodine application in guinea pigs and the effect of L-carnitine on this alteration.
    International journal of radiation biology, 2011, Volume: 87, Issue:1

    Topics: Animals; Arginine; Carnitine; Guinea Pigs; Heart; Homoarginine; Iodine Radioisotopes; Male; Muscle, Skeletal; Myocardium; Radiation-Protective Agents; Thyroid Hormones

2011
Posttranslational arginine methylation of lamin A/C during myoblast fusion.
    Biochimica et biophysica acta, 2011, Volume: 1814, Issue:2

    Topics: Amino Acid Sequence; Animals; Arginine; Blotting, Western; Cell Differentiation; Cells, Cultured; Electrophoresis, Gel, Two-Dimensional; Lamin Type A; Membrane Fusion; Methylation; Molecular Sequence Data; Muscle Development; Muscle Fibers, Skeletal; Myoblasts, Skeletal; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2011
Dimethylarginines and serotonin in the blood of spontaneously hypertensive rats.
    Bulletin of experimental biology and medicine, 2009, Volume: 148, Issue:6

    Topics: Animals; Arginine; Hydroxyindoleacetic Acid; Nitric Oxide; Rats; Rats, Inbred SHR; Rats, Wistar; Serotonin

2009
Asymmetric dimethylarginine as a risk factor for cardiovascular disease in Japanese patients with type 2 diabetes mellitus.
    Clinical endocrinology, 2011, Volume: 74, Issue:4

    Topics: Aged; Arginine; Asian People; Cardiovascular Diseases; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Regression Analysis; Risk Factors

2011
Time course of asymmetric dimethylarginine (ADMA) and oxidative stress in fructose-hypertensive rats: a model related to metabolic syndrome.
    Atherosclerosis, 2011, Volume: 214, Issue:2

    Topics: Animals; Aorta; Arginine; Blood Glucose; Blood Pressure; Body Weight; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fructose; Heart Rate; Hypertension; Male; Metabolic Syndrome; NADPH Oxidases; Nitric Oxide Synthase Type II; Oxidative Stress; Rats; Rats, Sprague-Dawley; Time Factors; Tyrosine; Vasodilation; Vasodilator Agents

2011
Symmetrical dimethylarginine outperforms CKD-EPI and MDRD-derived eGFR for the assessment of renal function in patients with adult congenital heart disease.
    Kidney & blood pressure research, 2011, Volume: 34, Issue:1

    Topics: Adult; Arginine; Biomarkers; Cross-Sectional Studies; Cystatin C; Female; Glomerular Filtration Rate; Heart Defects, Congenital; Humans; Kidney Failure, Chronic; Kidney Function Tests; Male; Young Adult

2011
Plasma dimethylarginines during the acute inflammatory response.
    European journal of clinical investigation, 2011, Volume: 41, Issue:6

    Topics: Acute-Phase Reaction; Aged; Aged, 80 and over; Arginine; Arthroplasty, Replacement, Knee; Cohort Studies; Dimethylamines; Enzyme Inhibitors; Female; Humans; Inflammation; Knee Joint; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Postoperative Complications

2011
Asymmetric dimethylarginine as an independent risk marker for mortality in ambulatory patients with peripheral arterial disease.
    Journal of internal medicine, 2011, Volume: 269, Issue:3

    Topics: Aged; Arginine; Biomarkers; Cardiovascular Diseases; Cerebrovascular Disorders; Enzyme Inhibitors; Epidemiologic Methods; Female; Germany; Humans; Male; Nitric Oxide Synthase; Peripheral Arterial Disease; Prognosis

2011
Simultaneous gas chromatography-tandem mass spectrometry quantification of symmetric and asymmetric dimethylarginine in human urine.
    Analytical biochemistry, 2011, Jun-01, Volume: 413, Issue:1

    Topics: Adult; Arginine; Gas Chromatography-Mass Spectrometry; Humans; Stereoisomerism; Tandem Mass Spectrometry

2011
Systemic inflammation is linked to low arginine and high ADMA plasma levels resulting in an unfavourable NOS substrate-to-inhibitor ratio: the Hoorn Study.
    Clinical science (London, England : 1979), 2011, Volume: 121, Issue:2

    Topics: Aged; Aged, 80 and over; Arginine; Biomarkers; C-Reactive Protein; Cohort Studies; Female; Humans; Inflammation; Lipoproteins, LDL; Male; Middle Aged; Nitric Oxide Synthase; Oxidative Stress; Peroxidase

2011
Effects of coronary revascularization with or without cardiopulmonary bypass on plasma levels of asymmetric dimethylarginine.
    Coronary artery disease, 2011, Volume: 22, Issue:4

    Topics: Aged; Arginine; Biomarkers; Cardiopulmonary Bypass; Chromatography, High Pressure Liquid; Coronary Artery Bypass; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Reperfusion Injury; Tandem Mass Spectrometry

2011
Symmetric dimethylarginine (SDMA) is raised in women with polycystic ovary syndrome: a pilot study.
    Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 2011, Volume: 31, Issue:5

    Topics: Adult; Androgens; Anthropometry; Arginine; Case-Control Studies; Cross-Sectional Studies; Female; Glomerular Filtration Rate; Humans; Insulin; Kidney; Pilot Projects; Polycystic Ovary Syndrome; Young Adult

2011
Asymmetric dimethylarginine is increased in asthma.
    American journal of respiratory and critical care medicine, 2011, Oct-01, Volume: 184, Issue:7

    Topics: Adolescent; Animals; Arginine; Asthma; Biomarkers; Bronchial Hyperreactivity; Case-Control Studies; Child; Female; Humans; Male; Mice; Mice, Inbred BALB C; Nitric Oxide Synthase; Sputum

2011
Quantitation of L-arginine and asymmetric dimethylarginine in human plasma by LC-selective ion mode-MS for Type 2 diabetes mellitus study.
    Chemical & pharmaceutical bulletin, 2011, Volume: 59, Issue:7

    Topics: Adult; Aged; Arginine; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Female; Humans; Male; Mass Spectrometry; Middle Aged

2011
The biological effect of pharmacological treatment on dimethylaminohydrolases (DDAH-1) and cationic amino acid transporter-1 (CAT-1) expression in patients with acute congestive heart failure.
    Microvascular research, 2011, Volume: 82, Issue:3

    Topics: Acute Disease; Aged; Amidohydrolases; Arginine; Cardiovascular Agents; Cationic Amino Acid Transporter 1; Chromatography, High Pressure Liquid; Echocardiography, Doppler; Female; Heart Failure; Humans; Italy; Male; Middle Aged; Stroke Volume; Treatment Outcome; Ventricular Function, Left

2011
Asymmetric dimethylarginine predicts appropriate implantable cardioverter-defibrillator intervention in patients with left ventricular dysfunction.
    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2011, Volume: 13, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Arginine; Biomarkers; Defibrillators, Implantable; Follow-Up Studies; Humans; Male; Middle Aged; Nitric Oxide; Predictive Value of Tests; Prospective Studies; Retrospective Studies; Risk Factors; Tachycardia, Ventricular; Treatment Outcome; Ventricular Dysfunction, Left

2011
Symmetric dimethylarginine as a proinflammatory agent in chronic kidney disease.
    Clinical journal of the American Society of Nephrology : CJASN, 2011, Volume: 6, Issue:10

    Topics: Acetylcysteine; Aged; Aged, 80 and over; Arginine; Belgium; Biomarkers; Case-Control Studies; Cell Line; Chronic Disease; Cross-Sectional Studies; Female; Humans; Inflammation Mediators; Interleukin-6; Kidney Diseases; Linear Models; Male; Middle Aged; Monocytes; NF-kappa B; Predictive Value of Tests; ROC Curve; Tumor Necrosis Factor-alpha

2011
Simultaneous determination of L-arginine, asymmetric dimethylarginine, and symmetric dimethylarginine in the plasma of rodents with LC-MS/MS.
    Arzneimittel-Forschung, 2011, Volume: 61, Issue:6

    Topics: Animals; Arginine; Calibration; Chromatography, High Pressure Liquid; Indicators and Reagents; Male; Mass Spectrometry; Mice; Mice, Inbred ICR; Quality Control; Rats; Rats, Sprague-Dawley; Reference Standards; Reproducibility of Results; Tandem Mass Spectrometry

2011
Plasma symmetric dimethylarginine reference limits from the Framingham offspring cohort.
    Clinical chemistry and laboratory medicine, 2011, Volume: 49, Issue:11

    Topics: Age Factors; Aged; Arginine; Biomarkers; Blood Pressure; Body Mass Index; Chromatography, Liquid; Cohort Studies; Creatinine; Female; Homocysteine; Humans; Kidney; Kidney Failure, Chronic; Kidney Function Tests; Male; Middle Aged; Radioisotope Dilution Technique; Reference Values; Tandem Mass Spectrometry; United States

2011
Increased asymmetric dimethylarginine and enhanced inflammation are associated with impaired vascular reactivity in women with endometriosis.
    Atherosclerosis, 2011, Volume: 219, Issue:2

    Topics: Adult; Arginine; Biomarkers; Brachial Artery; C-Reactive Protein; Case-Control Studies; Endometriosis; Female; Humans; Inflammation Mediators; Interleukin-6; Japan; Least-Squares Analysis; Lipids; Regression Analysis; Serum Amyloid A Protein; Ultrasonography, Doppler; Up-Regulation; Vasodilation

2011
Adenosine A₁-receptor deficiency diminishes afferent arteriolar and blood pressure responses during nitric oxide inhibition and angiotensin II treatment.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2011, Volume: 301, Issue:6

    Topics: Angiotensin II; Animals; Arginine; Arterioles; Blood Pressure; Gene Expression Regulation; Kidney; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Receptor, Adenosine A1

2011
Is plasma symmetric dimethylarginine a suitable marker of renal function in children and adolescents?
    Scandinavian journal of urology and nephrology, 2012, Volume: 46, Issue:1

    Topics: Adolescent; Arginine; Biomarkers; Case-Control Studies; Child; Child, Preschool; Chronic Disease; Cross-Sectional Studies; Cystatin C; Disease Progression; Female; Glomerular Filtration Rate; Humans; Infant; Kidney; Kidney Diseases; Male; ROC Curve; Sensitivity and Specificity; Young Adult

2012
Ethnicity-specific differences in L-arginine status in South African men.
    Journal of human hypertension, 2012, Volume: 26, Issue:12

    Topics: Adult; Aged; Arginine; Black People; Cardiovascular Diseases; Cross-Sectional Studies; Humans; Hypertension; Linear Models; Male; Middle Aged; Multivariate Analysis; Prevalence; Risk Factors; South Africa; White People

2012
The combined ratios of L-arginine and asymmetric and symmetric dimethylarginine as biomarkers in spontaneously hypertensive rats.
    Translational research : the journal of laboratory and clinical medicine, 2012, Volume: 159, Issue:2

    Topics: Amidohydrolases; Animals; Arginine; Biomarkers; Blood Pressure; Hypertension; Male; Models, Animal; Nitric Oxide; Rats; Rats, Inbred SHR; Rats, Inbred WKY

2012
Optimization of the separation of NDA-derivatized methylarginines by capillary and microchip electrophoresis.
    Journal of laboratory automation, 2012, Volume: 17, Issue:1

    Topics: Arginine; Biomarkers; Cardiovascular Diseases; Electrophoresis, Capillary; Electrophoresis, Microchip; Humans; Lasers; Naphthalenes; Prognosis

2012
Birth by cesarean section is associated with elevated neonatal plasma levels of dimethylarginines.
    Pediatrics international : official journal of the Japan Pediatric Society, 2012, Volume: 54, Issue:4

    Topics: Arginine; Cesarean Section; Delivery, Obstetric; Female; Humans; Infant, Newborn; Male; Pregnancy

2012
Elevation of serum asymmetrical and symmetrical dimethylarginine in patients with advanced glaucoma.
    Investigative ophthalmology & visual science, 2012, Apr-18, Volume: 53, Issue:4

    Topics: Aged; Arginine; Biomarkers; Female; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; Male; Nitric Oxide Synthase; Retrospective Studies; Severity of Illness Index; Tandem Mass Spectrometry

2012
Nitric oxide synthase, ADMA, SDMA, and nitric oxide activity in the paraventricular nucleus throughout the etiology of renal wrap hypertension.
    American journal of physiology. Heart and circulatory physiology, 2012, Jun-01, Volume: 302, Issue:11

    Topics: Animals; Arginine; Blood Pressure; Disease Models, Animal; Enzyme Inhibitors; Hypertension, Renal; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley

2012
Osteopontin and symmetric dimethylarginine plasma levels in solitary functioning kidney in children.
    Acta paediatrica (Oslo, Norway : 1992), 2012, Volume: 101, Issue:8

    Topics: Adolescent; Arginine; Biomarkers; Case-Control Studies; Child; Child, Preschool; Congenital Abnormalities; Creatinine; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Humans; Infant; Kidney; Kidney Diseases; Kidney Function Tests; Male; Nephrectomy; Osteopontin; Retrospective Studies; ROC Curve

2012
Asymmetric dimethylarginine in adults with cystathionine β-synthase deficiency.
    Atherosclerosis, 2012, Volume: 222, Issue:2

    Topics: Adult; Arginine; Biomarkers; Chromatography, High Pressure Liquid; Endothelium, Vascular; Homocysteine; Homocystinuria; Humans

2012
Asymmetric dimethylarginine (ADMA), symmetric dimethylarginine (SDMA) and L-arginine in patients with arteriogenic and non-arteriogenic erectile dysfunction.
    International journal of andrology, 2012, Volume: 35, Issue:5

    Topics: Adult; Arginine; Erectile Dysfunction; Humans; Impotence, Vasculogenic; Male; Middle Aged

2012
Diagnostic value of plasma asymmetric and symmetric dimethylarginine levels in liver transplant recipients.
    Polskie Archiwum Medycyny Wewnetrznej, 2012, Volume: 122, Issue:7-8

    Topics: Alanine Transaminase; Arginine; Aspartate Aminotransferases; Biomarkers; Cadaver; Fibrosis; Humans; Kidney Transplantation; Predictive Value of Tests; Renal Insufficiency, Chronic

2012
Binding of the heterogeneous ribonucleoprotein K (hnRNP K) to the Epstein-Barr virus nuclear antigen 2 (EBNA2) enhances viral LMP2A expression.
    PloS one, 2012, Volume: 7, Issue:8

    Topics: Antibodies, Monoclonal; Antibody Specificity; Arginine; Cell Line; DNA; Epstein-Barr Virus Infections; Epstein-Barr Virus Nuclear Antigens; Gene Expression Regulation, Viral; Herpesvirus 4, Human; Heterogeneous-Nuclear Ribonucleoprotein K; Humans; Immunoprecipitation; Methylation; Molecular Sequence Data; Multiprotein Complexes; Mutant Proteins; Promoter Regions, Genetic; Protein Binding; Protein Transport; Repetitive Sequences, Amino Acid; snRNP Core Proteins; Transfection; Viral Matrix Proteins; Viral Proteins

2012
Diagnostical significance of dimethylarginine in the development of hepatorenal syndrome in patients with alcoholic liver cirrhosis.
    Vojnosanitetski pregled, 2012, Volume: 69, Issue:8

    Topics: Adult; Aged; Arginine; Biomarkers; Creatinine; Disease Progression; Hepatorenal Syndrome; Humans; Liver Cirrhosis, Alcoholic; Male; Middle Aged

2012
Estradiol, acting through estrogen receptor alpha, restores dimethylarginine dimethylaminohydrolase activity and nitric oxide production in oxLDL-treated human arterial endothelial cells.
    Molecular and cellular endocrinology, 2013, Jan-05, Volume: 365, Issue:1

    Topics: Amidohydrolases; Arginine; Blotting, Western; Cells, Cultured; Endothelium, Vascular; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens, Non-Steroidal; Humans; Isoenzymes; Lipoproteins, LDL; Nitric Oxide; Nitric Oxide Synthase Type III; Protein Stability; Protein-Arginine N-Methyltransferases; Receptors, Estrogen; Receptors, G-Protein-Coupled; Repressor Proteins; Umbilical Arteries

2013
Nitric oxide and carbon monoxide production and metabolism in preeclampsia.
    Reproductive sciences (Thousand Oaks, Calif.), 2013, Volume: 20, Issue:5

    Topics: Adult; Amidohydrolases; Arginine; Biomarkers; Blotting, Western; Carbon Monoxide; Case-Control Studies; Enzyme-Linked Immunosorbent Assay; Female; Heme Oxygenase-1; Humans; Nitric Oxide; Placenta; Pre-Eclampsia; Predictive Value of Tests; Pregnancy; Prospective Studies; Young Adult

2013
Parental history of premature coronary artery disease does not affect plasma levels of asymmetric dimethylarginine in young healthy adults.
    Polskie Archiwum Medycyny Wewnetrznej, 2012, Volume: 122, Issue:10

    Topics: Adult; Arginine; Biomarkers; Coronary Artery Disease; Female; Humans; Male; Medical History Taking; Risk Assessment; Young Adult

2012
INF-β1b therapy modulates L-arginine and nitric oxide metabolism in patients with relapse remittent multiple sclerosis.
    Journal of the neurological sciences, 2012, Dec-15, Volume: 323, Issue:1-2

    Topics: Adult; Arginase; Arginine; Biomarkers; Drug Monitoring; Female; Follow-Up Studies; Humans; Inflammation; Interferon beta-1b; Interferon-beta; Male; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Nitrates; Nitric Oxide; Nitrites; Nitroso Compounds; Severity of Illness Index; Sulfhydryl Compounds; Tyrosine; Young Adult

2012
Asymmetric and symmetric dimethylarginine and risk of secondary cardiovascular disease events and mortality in patients with stable coronary heart disease: the KAROLA follow-up study.
    Clinical research in cardiology : official journal of the German Cardiac Society, 2013, Volume: 102, Issue:3

    Topics: Aged; Arginine; Biomarkers; Cause of Death; Chromatography, Liquid; Coronary Disease; Female; Follow-Up Studies; Germany; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Multivariate Analysis; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Prospective Studies; Recurrence; Risk Assessment; Risk Factors; Tandem Mass Spectrometry; Time Factors

2013
ADMA, SDMA and L-arginine/ADMA ratio but not DDAH genetic polymorphisms are reliable predictors of diabetic nephropathy progression as identified by competing risk analysis.
    Kidney & blood pressure research, 2012, Volume: 36, Issue:1

    Topics: Adult; Aged; Amidohydrolases; Arginine; Cross-Sectional Studies; Czech Republic; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Progression; Female; Follow-Up Studies; Humans; Male; Methylation; Middle Aged; Multivariate Analysis; Polymorphism, Single Nucleotide; Predictive Value of Tests; Prognosis; Reproducibility of Results; Risk Factors

2012
Circulating levels of dimethylarginines, chronic kidney disease and long-term clinical outcome in non-ST-elevation myocardial infarction.
    PloS one, 2012, Volume: 7, Issue:11

    Topics: Aged; Arginine; Endpoint Determination; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Kidney Function Tests; Male; Middle Aged; Myocardial Infarction; Nitric Oxide; Proportional Hazards Models; Renal Insufficiency, Chronic; Treatment Outcome; Ultrasonography

2012
The L-Arginine-asymmetric dimethylarginine ratio is an independent predictor of mortality in dilated cardiomyopathy.
    Journal of cardiac failure, 2012, Volume: 18, Issue:12

    Topics: Arginine; Biomarkers; Cardiomyopathies; Cardiomyopathy, Dilated; Chromatography, Liquid; Creatinine; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Multivariate Analysis; Myocardial Ischemia; Natriuretic Peptide, Brain; Peptide Fragments; Severity of Illness Index; Tandem Mass Spectrometry

2012
Transsulfuration pathway thiols and methylated arginines: the Hunter Community Study.
    PloS one, 2013, Volume: 8, Issue:1

    Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Aging; Amidohydrolases; Arginine; Australia; C-Reactive Protein; Cardiovascular Diseases; Cohort Studies; Community Medicine; Cysteine; Dipeptides; Female; Glutathione; Homocysteine; Humans; Male; Middle Aged; Taurine

2013
Heat-assisted extraction for the determination of methylarginines in serum by CE.
    Electrophoresis, 2013, Volume: 34, Issue:11

    Topics: Arginine; Cardiovascular Diseases; Electrophoresis, Capillary; Hot Temperature; Humans; omega-N-Methylarginine; Solid Phase Extraction

2013
Effects of salvianolic acid A on plasma and tissue dimethylarginine levels in a rat model of myocardial infarction.
    Journal of cardiovascular pharmacology, 2013, Volume: 61, Issue:6

    Topics: Amidohydrolases; Animals; Arginine; Caffeic Acids; Chromatography, High Pressure Liquid; Creatinine; Disease Models, Animal; Heart Ventricles; Kidney; Lactates; Liver; Male; Myocardial Infarction; Proton Pump Inhibitors; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry

2013
The methylarginines NMMA, ADMA, and SDMA are ubiquitous constituents of the main vegetables of human nutrition.
    Nitric oxide : biology and chemistry, 2013, Apr-01, Volume: 30

    Topics: Arginine; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Vegetables

2013
Influence of ezetimibe on ADMA-DDAH-NO pathway in rat liver subjected to partial ischemia followed by global reperfusion.
    Pharmacological reports : PR, 2013, Volume: 65, Issue:1

    Topics: Amidohydrolases; Animals; Anticholesteremic Agents; Arginine; Azetidines; Ezetimibe; Liver; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Reperfusion Injury; RNA, Messenger; Time Factors

2013
Increased symmetrical dimethylarginine in ischemic acute kidney injury as a causative factor of renal L-arginine deficiency.
    Translational research : the journal of laboratory and clinical medicine, 2013, Volume: 162, Issue:2

    Topics: Acute Kidney Injury; Amidohydrolases; Animals; Arginine; Blotting, Western; Chromatography, High Pressure Liquid; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Intracellular Signaling Peptides and Proteins; Kidney; Kidney Function Tests; Protein-Arginine N-Methyltransferases; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Reperfusion Injury; Tandem Mass Spectrometry

2013
High levels of asymmetric dimethylarginine are strongly associated with low HDL in patients with acute myocardial infarction.
    PloS one, 2013, Volume: 8, Issue:6

    Topics: Aged; Arginine; Chromatography, High Pressure Liquid; Female; Humans; Lipoproteins, HDL; Male; Middle Aged; Myocardial Infarction

2013
Plasma concentrations of arginine and asymmetric dimethylarginine do not reflect their intracellular concentrations in peripheral blood mononuclear cells.
    Metabolism: clinical and experimental, 2013, Volume: 62, Issue:10

    Topics: Arginine; Biomarkers; Homoarginine; Humans; Leukocytes, Mononuclear; Nitric Oxide

2013
Serum methylarginines and incident depression in a cohort of older adults.
    Journal of affective disorders, 2013, Volume: 151, Issue:2

    Topics: Aged; Aged, 80 and over; Arginine; Depression; Female; Follow-Up Studies; Humans; Incidence; Male; Middle Aged; New South Wales; Nitric Oxide Synthase

2013
Regulation and prognostic relevance of symmetric dimethylarginine serum concentrations in critical illness and sepsis.
    Mediators of inflammation, 2013, Volume: 2013

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arginine; Biomarkers; Critical Care; Critical Illness; Female; Gene Expression Regulation; Humans; Inflammation; Male; Middle Aged; Multiple Organ Failure; Multivariate Analysis; Prognosis; Regression Analysis; Risk Factors; Sepsis; Young Adult

2013
Nitric oxide synthetic pathway in red blood cells is impaired in coronary artery disease.
    PloS one, 2013, Volume: 8, Issue:8

    Topics: Aged; Arginine; Chromatography, High Pressure Liquid; Coronary Artery Disease; Erythrocytes; Female; Glutathione; Humans; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Tandem Mass Spectrometry

2013
Effects of acute and chronic stress on the L-arginine nitric oxide pathway in black and white South Africans: the sympathetic activity and ambulatory blood pressure in Africans study.
    Psychosomatic medicine, 2013, Volume: 75, Issue:8

    Topics: Acute Disease; Adult; Arginine; Black People; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cardiovascular Diseases; Chronic Disease; Cold Temperature; Cross-Sectional Studies; Disease Susceptibility; Female; Hemodynamics; Humans; Male; Middle Aged; Motor Activity; Nitric Oxide; Pressure; Rest; South Africa; Stress, Psychological; Stroop Test; White People

2013
Mitochondrial protein BmPAPI modulates the length of mature piRNAs.
    RNA (New York, N.Y.), 2013, Volume: 19, Issue:10

    Topics: Animals; Arginine; Argonaute Proteins; Blotting, Northern; Blotting, Western; Bombyx; Carrier Proteins; DNA Primers; Drosophila melanogaster; Drosophila Proteins; Female; Fluorescent Antibody Technique; Germ Cells; Immunoprecipitation; Membrane Transport Proteins; Mitochondria; Mitochondrial Proteins; Ovary; Protein Structure, Tertiary; Real-Time Polymerase Chain Reaction; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA-Induced Silencing Complex; RNA, Messenger; RNA, Small Interfering; Surface Plasmon Resonance

2013
Changes in biomarkers associated with living kidney donation.
    American journal of nephrology, 2013, Volume: 38, Issue:3

    Topics: Adult; Arginine; Biomarkers; Cardiovascular Diseases; Cohort Studies; Female; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Glomerular Filtration Rate; Humans; Kidney Transplantation; Living Donors; Male; Middle Aged; Risk Factors; Tissue and Organ Harvesting

2013
Symmetrical dimethylarginine predicts mortality in the general population: observations from the Dallas heart study.
    Arteriosclerosis, thrombosis, and vascular biology, 2013, Volume: 33, Issue:11

    Topics: Adult; Aged; Arginine; Cardiovascular Diseases; Female; Follow-Up Studies; Humans; Male; Middle Aged; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Risk Factors; Texas

2013
Oxidative stress in hypobaric hypoxia and influence on vessel-tone modifying mediators.
    High altitude medicine & biology, 2013, Volume: 14, Issue:3

    Topics: Adult; Aged; Altitude; Altitude Sickness; Amino Acids; Arginine; Blood Vessels; Female; Humans; Hydroxyeicosatetraenoic Acids; Hypoxia; Male; Methionine; Middle Aged; Nitric Oxide Synthase; Oxidative Stress; Oxygen; Pressure; Serotonin

2013
Gender differences in oxidative and nitrosative stress parameters in kidney transplant patients on tacrolimus-based immunosuppression.
    International urology and nephrology, 2014, Volume: 46, Issue:6

    Topics: Adult; Advanced Oxidation Protein Products; Arginine; Catalase; Female; Healthy Volunteers; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged; Mycophenolic Acid; Nitrates; Nitrites; Oxidative Stress; Prednisone; Sex Factors; Sulfhydryl Compounds; Tacrolimus; Thiobarbituric Acid Reactive Substances

2014
Memory impairment is associated with serum methylarginines in older adults.
    Current Alzheimer research, 2014, Volume: 11, Issue:1

    Topics: Aged; Aged, 80 and over; Arginine; Atrial Fibrillation; Cohort Studies; Diabetes Mellitus; Educational Status; Female; Humans; Logistic Models; Male; Memory Disorders; Middle Aged; Multivariate Analysis; Neuropsychological Tests; Odds Ratio; Severity of Illness Index

2014
Assessment of endothelial dysfunction: the role of symmetrical dimethylarginine and proinflammatory markers in chronic kidney disease and renal transplant recipients.
    Disease markers, 2013, Volume: 35, Issue:3

    Topics: Adult; Arginine; Arteriosclerosis; Biomarkers; Brachial Artery; C-Reactive Protein; Endothelium, Vascular; Female; Humans; Kidney Transplantation; Male; Middle Aged; Renal Insufficiency, Chronic; Superoxides; Vasodilation

2013
Genetic and environmental determinants of dimethylarginines and association with cardiovascular disease in patients with type 2 diabetes.
    Diabetes care, 2014, Volume: 37, Issue:3

    Topics: Aged; Arginine; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Environment; Female; Genotype; Humans; Intermittent Claudication; Male; Middle Aged; Polymorphism, Single Nucleotide; Risk Factors

2014
Are levels of NT-proBNP and SDMA useful to determine diastolic dysfunction in chronic kidney disease and renal transplant patients?
    Journal of clinical laboratory analysis, 2013, Volume: 27, Issue:6

    Topics: Adult; Aged; Arginine; Biomarkers; Diastole; Female; Humans; Hypertension; Kidney Transplantation; Male; Middle Aged; Natriuretic Peptide, Brain; Peptide Fragments; Renal Insufficiency, Chronic

2013
Asymmetric and symmetric dimethylarginine in adolescents with hyperuricemia.
    Disease markers, 2013, Volume: 35, Issue:5

    Topics: Adolescent; Arginine; Biomarkers; Case-Control Studies; Child; Female; Humans; Hyperuricemia; Male; Uric Acid

2013
L-arginine, asymmetric dimethylarginine, and symmetric dimethylarginine in plasma and synovial fluid of patients with knee osteoarthritis.
    Medical science monitor : international medical journal of experimental and clinical research, 2013, Nov-26, Volume: 19

    Topics: Arginine; Case-Control Studies; Humans; Nitric Oxide; Osteoarthritis, Knee; Signal Transduction; Synovial Fluid; Thiobarbituric Acid Reactive Substances

2013
Fam118B, a newly identified component of Cajal bodies, is required for Cajal body formation, snRNP biogenesis and cell viability.
    Journal of cell science, 2014, May-01, Volume: 127, Issue:Pt 9

    Topics: Arginine; Cell Line; Cell Proliferation; Cell Survival; Coiled Bodies; HeLa Cells; Humans; Immunoprecipitation; Reverse Transcriptase Polymerase Chain Reaction; Ribonucleoproteins, Small Nuclear; RNA Interference; SMN Complex Proteins

2014
Asymmetric dimethylarginine responses during interferon-α-induced depression in patients with chronic hepatitis C infection.
    Psychosomatic medicine, 2014, Volume: 76, Issue:3

    Topics: Adult; Analysis of Variance; Antiviral Agents; Arginine; Cardiovascular Diseases; Chromatography, Liquid; Depression; Depressive Disorder; Drug Therapy, Combination; Female; Hepatitis C, Chronic; Humans; Interferon-alpha; Male; Nitric Oxide Synthase; Prospective Studies; Psychiatric Status Rating Scales; Regression Analysis; Ribavirin; Risk Factors; Time Factors

2014
Structural determinants for the strict monomethylation activity by trypanosoma brucei protein arginine methyltransferase 7.
    Structure (London, England : 1993), 2014, May-06, Volume: 22, Issue:5

    Topics: Amino Acid Sequence; Arginine; Catalytic Domain; Crystallography, X-Ray; Guanidine; Histones; Methylation; Models, Molecular; Molecular Sequence Data; Protein Multimerization; Protein-Arginine N-Methyltransferases; Protozoan Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine; Trypanosoma brucei brucei

2014
ADMA/SDMA in elderly subjects with asymptomatic carotid atherosclerosis: values and site-specific association.
    International journal of molecular sciences, 2014, Apr-15, Volume: 15, Issue:4

    Topics: Aged; Aged, 80 and over; Arginine; C-Reactive Protein; Carotid Arteries; Carotid Artery Diseases; Carotid Intima-Media Thickness; Cholesterol; Cholesterol, LDL; Female; Humans; Male; Middle Aged; Triglycerides

2014
Incidence of all-cause and cardiovascular mortality predicted by symmetric dimethylarginine in the population-based study of health in pomerania.
    PloS one, 2014, Volume: 9, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Arginine; Cardiovascular Diseases; Female; Humans; Incidence; Male; Middle Aged; Young Adult

2014
HDL in children with CKD promotes endothelial dysfunction and an abnormal vascular phenotype.
    Journal of the American Society of Nephrology : JASN, 2014, Volume: 25, Issue:11

    Topics: Adolescent; Arginine; Biomarkers; Child; Cholesterol, HDL; Cholesterol, LDL; Endothelium, Vascular; Female; Humans; Kidney Transplantation; Male; Nitric Oxide; Renal Dialysis; Renal Insufficiency, Chronic; Triglycerides; Vascular Diseases

2014
Asymmetric and symmetric dimethylarginine are associated with coronary artery lesions in Kawasaki disease.
    The Journal of pediatrics, 2014, Volume: 165, Issue:2

    Topics: Arginine; Biomarkers; Child, Preschool; Coronary Artery Disease; Coronary Vessels; Female; Humans; Immunoglobulins, Intravenous; Infant; Male; Mucocutaneous Lymph Node Syndrome

2014
Serum reference intervals of homoarginine, ADMA, and SDMA in the study of health in Pomerania.
    Clinical chemistry and laboratory medicine, 2014, Volume: 52, Issue:12

    Topics: Adult; Aged; Arginine; Biomarkers; Body Mass Index; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Female; Homoarginine; Humans; Male; Middle Aged; Reference Values; Renal Insufficiency, Chronic; Risk Factors; Tandem Mass Spectrometry

2014
Time course of asymmetric dimethylarginine and symmetric dimethylarginine levels after successful renal transplantation.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2014, Volume: 29, Issue:10

    Topics: Adult; Aged; Arginine; Biomarkers; Case-Control Studies; Chromatography, High Pressure Liquid; Female; Glomerular Filtration Rate; Humans; Kidney Transplantation; Male; Middle Aged; Postoperative Complications; Prospective Studies; Renal Insufficiency, Chronic; Risk Factors; Young Adult

2014
Association between brachial-ankle pulse wave velocity and the ratio of l-arginine to asymmetric dimethylarginine in patients undergoing coronary angiography.
    Journal of cardiology, 2015, Volume: 65, Issue:4

    Topics: Aged; Ankle Brachial Index; Arginine; Blood Pressure; Coronary Angiography; Coronary Artery Disease; Cross-Sectional Studies; Female; Heart Rate; Hematocrit; Hemoglobins; Humans; Kidney; Male; Middle Aged; Natriuretic Peptide, Brain; Pulse Wave Analysis; Vascular Stiffness

2015
Monocyte activation, but not microbial translocation, is independently associated with markers of endovascular dysfunction in HIV-infected patients receiving cART.
    Journal of acquired immune deficiency syndromes (1999), 2014, Dec-01, Volume: 67, Issue:4

    Topics: Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Arginine; Bacterial Translocation; Biomarkers; Cardiovascular Diseases; Female; Fibrin Fibrinogen Degradation Products; HIV Infections; Humans; Lipopolysaccharide Receptors; Lipopolysaccharides; Male; Middle Aged; Monocytes

2014
Associations of methylarginines and homoarginine with diastolic dysfunction and cardiovascular risk factors in patients with preserved left ventricular ejection fraction.
    Journal of cardiac failure, 2014, Volume: 20, Issue:12

    Topics: Aged; Aged, 80 and over; Arginine; Biomarkers; Cardiovascular Diseases; Echocardiography, Doppler; Female; Heart Failure, Diastolic; Homoarginine; Humans; Logistic Models; Male; Middle Aged; Nitric Oxide; Reference Values; Risk Factors; Sensitivity and Specificity; Severity of Illness Index; Stroke Volume

2014
Genome-wide association study of L-arginine and dimethylarginines reveals novel metabolic pathway for symmetric dimethylarginine.
    Circulation. Cardiovascular genetics, 2014, Volume: 7, Issue:6

    Topics: Adult; Aged; Amidohydrolases; Arginine; Binding Sites; Cohort Studies; Female; Genetic Loci; Genome-Wide Association Study; Genotype; HEK293 Cells; Humans; Male; Mediator Complex; Middle Aged; Polymorphism, Single Nucleotide; Protein Structure, Tertiary; Risk Factors; Stroke; Substrate Specificity; Transaminases

2014
Symmetric dimethylarginine alters endothelial nitric oxide activity in glomerular endothelial cells.
    Cellular signalling, 2015, Volume: 27, Issue:1

    Topics: Animals; Arginine; Calcium Channels; Cell Line; Endothelial Cells; Kidney Glomerulus; Mice; Nitric Oxide; Nitric Oxide Synthase Type III; Protein Multimerization; Signal Transduction; Superoxides; TRPV Cation Channels; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2

2015
Amino acid N-acetylation: metabolic elimination of symmetric dimethylarginine as symmetric N(α)-acetyldimethylarginine, determined in human plasma and urine by LC-MS/MS.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2015, Jan-15, Volume: 975

    Topics: Acetylation; Adult; Arginine; Calibration; Chromatography, Liquid; Graphite; Humans; Male; Middle Aged; Tandem Mass Spectrometry; Young Adult

2015
Comparison of serum concentrations of symmetric dimethylarginine and creatinine as kidney function biomarkers in healthy geriatric cats fed reduced protein foods enriched with fish oil, L-carnitine, and medium-chain triglycerides.
    Veterinary journal (London, England : 1997), 2014, Volume: 202, Issue:3

    Topics: Age Factors; Animal Feed; Animals; Arginine; Biomarkers; Blood Chemical Analysis; Blood Proteins; Body Composition; Body Mass Index; Cats; Creatinine; Cross-Sectional Studies; Diet; Diet, Protein-Restricted; Fatty Acids, Omega-3; Female; Glomerular Filtration Rate; Kidney Function Tests; Male

2014
Soluble CD14 is associated with markers of vascular dysfunction in bariatric surgery patients.
    Metabolic syndrome and related disorders, 2015, Volume: 13, Issue:3

    Topics: Adipose Tissue; Adult; Age Factors; Arginine; Bariatric Surgery; Biomarkers; Female; Humans; Lipopolysaccharide Receptors; Lipopolysaccharides; Male; Middle Aged; Monocytes; Obesity; Prospective Studies; Risk Factors; Sex Factors; Vascular Diseases

2015
PRMT9 is a type II methyltransferase that methylates the splicing factor SAP145.
    Nature communications, 2015, Mar-04, Volume: 6

    Topics: Arginine; Base Sequence; Binding Sites; Chromatography, Ion Exchange; Chromatography, Thin Layer; DNA Methylation; DNA Primers; F-Box Proteins; Fluorescent Antibody Technique; High-Throughput Nucleotide Sequencing; Humans; Immunoprecipitation; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein-Arginine N-Methyltransferases; RNA Splicing Factors; RNA-Binding Proteins; Sequence Alignment; Sequence Analysis, RNA; Survival of Motor Neuron 1 Protein

2015
The role of asymmetric and symmetric dimethylarginine in acute deep vein thrombosis.
    Annals of vascular surgery, 2015, Volume: 29, Issue:5

    Topics: Acute Disease; Adult; Arginine; Biomarkers; Case-Control Studies; Chromatography, High Pressure Liquid; Female; Humans; Male; Middle Aged; Treatment Outcome; Venous Thrombosis

2015
Increased levels of symmetric dimethyl-arginine are associated with all-cause mortality in patients with symptomatic peripheral arterial disease.
    Journal of vascular surgery, 2015, Volume: 61, Issue:5

    Topics: Aged; Ankle Brachial Index; Arginine; Arterial Occlusive Diseases; Biomarkers; Cause of Death; Female; Follow-Up Studies; Humans; Intermittent Claudication; Ischemia; Male; Middle Aged; Predictive Value of Tests

2015
Nitric oxide dysregulation in patients with heart failure: the association of depressive symptoms with L-arginine, asymmetric dimethylarginine, symmetric dimethylarginine, and isoprostane.
    Psychosomatic medicine, 2015, Volume: 77, Issue:3

    Topics: Aged; Arginine; Depression; Female; Heart Failure; Humans; Isoprostanes; Linear Models; Male; Middle Aged; Nitric Oxide; Oxidative Stress

2015
Plasma asymmetric and symmetric dimethylarginine in a rat model of endothelial dysfunction induced by acute hyperhomocysteinemia.
    Amino acids, 2015, Volume: 47, Issue:9

    Topics: Amidohydrolases; Animals; Arginine; Cathepsin D; Disease Models, Animal; Endothelium, Vascular; Gene Expression Regulation; Hyperhomocysteinemia; Liver; Male; Methionine; Rats; Rats, Wistar; Ubiquitin

2015
Physical exercise reduces synthesis of ADMA, SDMA, and L-Arg.
    Frontiers in bioscience (Elite edition), 2015, 06-01, Volume: 7, Issue:3

    Topics: Arginine; Biomarkers; Coronary Artery Disease; Exercise; Female; Humans; Male; Middle Aged; Nitric Oxide

2015
L-Arginine and SDMA Serum Concentrations Are Associated with Subclinical Atherosclerosis in the Study of Health in Pomerania (SHIP).
    PloS one, 2015, Volume: 10, Issue:6

    Topics: Aged; Aged, 80 and over; Arginine; Atherosclerosis; Carotid Intima-Media Thickness; Carotid Stenosis; Cross-Sectional Studies; Female; Germany; Humans; Male; Middle Aged

2015
Dimethylarginines as biomarkers for the kidney transplant management in methylmalonic aciduria.
    Nephrology (Carlton, Vic.), 2015, Volume: 20, Issue:8

    Topics: Adult; Allografts; Amino Acid Metabolism, Inborn Errors; Arginine; Biomarkers; Cause of Death; Disease Progression; Fatal Outcome; Humans; Immunosuppressive Agents; Kidney Failure, Chronic; Kidney Transplantation; Living Donors; Male; Pancreatitis; Predictive Value of Tests; Risk Factors; Time Factors; Treatment Outcome

2015
Asymmetric dimethylarginine in experimental breast cancer; action of Vitamin C and E.
    JPMA. The Journal of the Pakistan Medical Association, 2015, Volume: 65, Issue:8

    Topics: Animals; Antioxidants; Arginase; Arginine; Ascorbic Acid; Female; Mammary Neoplasms, Experimental; Mice; Nitric Oxide; Nitric Oxide Synthase; Vitamin E

2015
The effect of nephropathy on plasma sphingosine 1-phosphate concentrations in patients with type 2 diabetes.
    Clinical biochemistry, 2015, Volume: 48, Issue:18

    Topics: Albuminuria; Apolipoproteins; Apolipoproteins M; Arginine; Biological Transport; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Humans; Lipocalins; Lysophospholipids; Male; Middle Aged; Sphingosine; Triglycerides

2015
Asymmetric dimethylarginine is transported by the mitochondrial carrier SLC25A2.
    Amino acids, 2016, Volume: 48, Issue:2

    Topics: Amino Acid Transport Systems, Basic; Arginine; Biological Transport; Carrier Proteins; Cell Line, Tumor; Humans; Kidney Tubules, Proximal; Mitochondria; Mitochondrial Membranes; Transaminases

2016
A robust distribution-free test for genetic association studies of quantitative traits.
    Statistical applications in genetics and molecular biology, 2015, Volume: 14, Issue:5

    Topics: Arginine; Case-Control Studies; Computer Simulation; Data Interpretation, Statistical; Genetic Association Studies; Genetic Predisposition to Disease; Humans; Models, Genetic; Models, Statistical; Monte Carlo Method; Phenotype; Polymorphism, Single Nucleotide; Quantitative Trait Loci; Transaminases

2015
Serum amine-based metabolites and their association with outcomes in primary prevention implantable cardioverter-defibrillator patients.
    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2016, Volume: 18, Issue:9

    Topics: Aged; Amines; Arginine; Biomarkers; Death, Sudden, Cardiac; Defibrillators, Implantable; Electric Countershock; Female; Heart Failure; Humans; Kynurenine; Male; Metabolomics; Methylhistidines; Middle Aged; Predictive Value of Tests; Primary Prevention; Prospective Studies; Risk Factors; Time Factors; Treatment Outcome; United States

2016
Symmetric Dimethylarginine Is Not Associated with Cumulative Inflammatory Load or Classical Cardiovascular Risk Factors in Rheumatoid Arthritis: A 6-Year Follow-Up Study.
    Mediators of inflammation, 2015, Volume: 2015

    Topics: Aged; Area Under Curve; Arginine; Arthritis, Rheumatoid; Atherosclerosis; Blood Sedimentation; C-Reactive Protein; Cardiovascular Diseases; Cohort Studies; Cytokines; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Humans; Inflammation; Male; Middle Aged; Risk Factors

2015
ADMA, subclinical changes and atrial fibrillation in the general population.
    International journal of cardiology, 2016, Jan-15, Volume: 203

    Topics: Adult; Aged; Arginine; Atrial Fibrillation; Biomarkers; Chromatography, Liquid; Echocardiography; Electrocardiography; Female; Germany; Humans; Male; Middle Aged; Morbidity; omega-N-Methylarginine; Oxidative Stress; Population Surveillance; Tandem Mass Spectrometry

2016
Nitric Oxide-Related Biological Pathways in Patients with Major Depression.
    PloS one, 2015, Volume: 10, Issue:11

    Topics: Adult; Arginase; Arginine; Biological Availability; Case-Control Studies; Demography; Depressive Disorder, Major; Female; Humans; Male; Middle Aged; Nitric Oxide; Psychometrics; Signal Transduction

2015
Methylarginines in Mice with Experimental Atherosclerosis.
    Bulletin of experimental biology and medicine, 2015, Volume: 160, Issue:1

    Topics: Animals; Arginine; Atherosclerosis; Cholesterol; Endothelium, Vascular; Male; Mice; Mice, Inbred CBA; Nitric Oxide Synthase; omega-N-Methylarginine; Poloxamer; Triglycerides

2015
Acetylation of asymmetric and symmetric dimethylarginine: an undercharacterized pathway of metabolism of endogenous methylarginines.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2016, Volume: 31, Issue:1

    Topics: Acetylation; Animals; Arginine; Chromatography, Liquid; Kidney; Male; Metabolic Networks and Pathways; Mice; Mice, Inbred C57BL; Nephrectomy; Organ Specificity; Protein Processing, Post-Translational

2016
L-Arginine Derivatives Are Associated with the Hyperthyroid State in the General Population.
    Thyroid : official journal of the American Thyroid Association, 2016, Volume: 26, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Arginine; Atherosclerosis; Cross-Sectional Studies; Female; Germany; Humans; Hyperthyroidism; Male; Middle Aged; Regression Analysis; Thyroid Function Tests; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine; Young Adult

2016
Changes in Biliary Levels of Arginine and its Methylated Derivatives after Hepatic Ischaemia/Reperfusion.
    Basic & clinical pharmacology & toxicology, 2016, Volume: 119, Issue:1

    Topics: Alanine Transaminase; Alkaline Phosphatase; Amidohydrolases; Amino Acid Transport Systems, Basic; Animals; Arginine; Aspartate Aminotransferases; Bile; Citrulline; Liver; Liver Diseases; Male; Nitric Oxide; Rats; Rats, Wistar; Reperfusion Injury; RNA, Messenger

2016
Whole-body synthesis of L-homoarginine in pigs and rats supplemented with L-arginine.
    Amino acids, 2016, Volume: 48, Issue:4

    Topics: Animal Feed; Animals; Arginine; Body Weight; Creatinine; Dietary Supplements; Female; Glycine max; Homoarginine; Male; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Swine; Zea mays

2016
Assessment of heat shock proteins and endothelial dysfunction in acute pulmonary embolism.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2016, Volume: 27, Issue:4

    Topics: Acute Disease; Adult; Aged; Arginine; Biomarkers; Case-Control Studies; Endothelium, Vascular; Female; Gene Expression; Heat-Shock Proteins; HSP27 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Humans; Male; Middle Aged; Molecular Chaperones; Oxidative Stress; Oxygen; Pulmonary Artery; Pulmonary Embolism

2016
The separation and analysis of symmetric and asymmetric dimethylarginine and other hydrophilic isobaric compounds using aqueous normal phase chromatography.
    Journal of chromatography. A, 2016, Apr-08, Volume: 1441

    Topics: Arginine; Case-Control Studies; Chromatography, Liquid; Humans; Hydrophobic and Hydrophilic Interactions; Silicates; Tuberculosis, Pulmonary; Water

2016
Positive Impact of Nutritional Interventions on Serum Symmetric Dimethylarginine and Creatinine Concentrations in Client-Owned Geriatric Cats.
    PloS one, 2016, Volume: 11, Issue:4

    Topics: Age Factors; Animal Nutritional Physiological Phenomena; Animals; Arginine; Biomarkers; Cats; Creatinine; Diet; Female; Kidney Function Tests; Male; Ownership; Renal Insufficiency, Chronic

2016
Serum Concentrations of Symmetric Dimethylarginine and Creatinine in Dogs with Naturally Occurring Chronic Kidney Disease.
    Journal of veterinary internal medicine, 2016, Volume: 30, Issue:3

    Topics: Animals; Arginine; Azotemia; Biomarkers; Creatinine; Dog Diseases; Dogs; Female; Glomerular Filtration Rate; Male; Renal Insufficiency, Chronic; Retrospective Studies

2016
Detrimental effects of a bout of physical exercise on circulating endogenous inhibitors of endothelial function in patients with coronary artery disease.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2017, Volume: 18, Issue:8

    Topics: Adult; Aged; Arginine; Biomarkers; Case-Control Studies; Coronary Artery Disease; Echocardiography; Exercise; Exercise Test; Female; Humans; Male; Middle Aged; Nitric Oxide Synthase; Risk Factors; Young Adult

2017
Determination of Asymmetric and Symmetric Dimethylarginine in Serum from Patients with Chronic Kidney Disease: UPLC-MS/MS versus ELISA.
    Toxins, 2016, 05-13, Volume: 8, Issue:5

    Topics: Arginine; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Humans; Renal Insufficiency, Chronic; Tandem Mass Spectrometry

2016
High Levels of Methylarginines Were Associated With Increased Mortality in Patients With Severe Sepsis.
    Shock (Augusta, Ga.), 2016, Volume: 46, Issue:4

    Topics: Aged; Arginine; Female; Humans; Male; Middle Aged; Nitric Oxide; Proportional Hazards Models; Sepsis; Shock, Septic

2016
Correlation of the L-Arginine Pathway with Thrombo-Inflammation May Contribute to the Outcome of Acute Ischemic Stroke.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2016, Volume: 25, Issue:8

    Topics: Aged; Aged, 80 and over; Analysis of Variance; Arginine; Brain Ischemia; Chemokine CCL2; Cytokines; Female; Humans; Inflammation; Male; Middle Aged; P-Selectin; Severity of Illness Index; Signal Transduction; Statistics as Topic; Stroke; Time Factors

2016
Asymmetric dimethylarginine, related arginine derivatives, and incident atrial fibrillation.
    American heart journal, 2016, Volume: 176

    Topics: Aged; Arginine; Atrial Fibrillation; Biomarkers; Cohort Studies; Female; Humans; Incidence; Male; Middle Aged; Oxidative Stress; Proportional Hazards Models; Reproducibility of Results; Statistics as Topic

2016
Endothelin 1, ADMA and SDMA in pregnancies with obstetric and thrombotic antiphospholipid syndrome.
    Journal of reproductive immunology, 2016, Volume: 116

    Topics: Adult; Antiphospholipid Syndrome; Arginine; Chronic Disease; Endothelin-1; Endothelium, Vascular; Female; Humans; Hypertension; Pre-Eclampsia; Pregnancy; Prognosis; Thrombosis; Young Adult

2016
Comparison of symmetric dimethylarginine with creatinine, cystatin C and their eGFR equations as markers of kidney function.
    Clinical biochemistry, 2016, Volume: 49, Issue:15

    Topics: Adult; Aged; Arginine; Biomarkers; Creatinine; Cystatin C; Female; Glomerular Filtration Rate; Humans; Kidney Function Tests; Male; Middle Aged; Young Adult

2016
Arginines Plasma Concentration and Oxidative Stress in Mild to Moderate COPD.
    PloS one, 2016, Volume: 11, Issue:8

    Topics: Age Factors; Aged; Aged, 80 and over; Arginine; Aryldialkylphosphatase; Biomarkers; Case-Control Studies; Female; Forced Expiratory Volume; Humans; Linear Models; Male; Middle Aged; Nitric Oxide; Oxidative Stress; Pulmonary Disease, Chronic Obstructive; Severity of Illness Index; Sex Factors; Taurine

2016
Evaluation of serum cystatin-C and symmetric dimethylarginine concentrations in dogs with heart failure from chronic mitral valvular insufficiency.
    The Journal of veterinary medical science, 2017, Jan-20, Volume: 79, Issue:1

    Topics: Animals; Arginine; Biomarkers; Blood Urea Nitrogen; Creatinine; Cystatin C; Dog Diseases; Dogs; Glomerular Filtration Rate; Heart Failure; Mitral Valve Insufficiency

2017
Diabetes-linked transcription factor HNF4α regulates metabolism of endogenous methylarginines and β-aminoisobutyric acid by controlling expression of alanine-glyoxylate aminotransferase 2.
    Scientific reports, 2016, 10-18, Volume: 6

    Topics: Aminoisobutyric Acids; Animals; Arginine; Cardiovascular Diseases; Cell Line; Diabetes Mellitus, Type 2; Gene Expression Regulation; Hepatocyte Nuclear Factor 4; Humans; Liver; Mice; Mice, Inbred C57BL; Mice, Knockout; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Risk; RNA, Small Interfering; Transaminases

2016
Higher serum asymmetric dimethylarginine is related to higher risk of heart failure in the EPIC-Potsdam study.
    Amino acids, 2017, Volume: 49, Issue:1

    Topics: Adult; Aged; Arginine; Biomarkers; Feeding Behavior; Female; Germany; Heart Failure; Humans; Male; Middle Aged; Myocardial Infarction; Prognosis; Proportional Hazards Models; Prospective Studies; Risk

2017
Comments on Boelaert et al. Determination of Asymmetric and Symmetric Dimethylarginine in Serum from Patients with Chronic Kidney Disease: UPLC-MS/MS versus ELISA. Toxins 2016, 8, 149.
    Toxins, 2016, 10-27, Volume: 8, Issue:11

    Topics: Arginine; Enzyme-Linked Immunosorbent Assay; Humans; Renal Insufficiency, Chronic; Tandem Mass Spectrometry

2016
Response to Tsikas et al. Comments on Boelaert et al. Determination of Asymmetric and Symmetric Dimethylarginine in Serum from Patients with Chronic Kidney Disease: UPLC-MS/MS versus ELISA. Toxins 2016, 8, 149.
    Toxins, 2016, 10-27, Volume: 8, Issue:11

    Topics: Arginine; Enzyme-Linked Immunosorbent Assay; Humans; Renal Insufficiency, Chronic; Tandem Mass Spectrometry

2016
l-Arginine Pathway Metabolites Predict Need for Intra-operative Shunt During Carotid Endarterectomy.
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2016, Volume: 52, Issue:6

    Topics: Aged; Anaerobiosis; Area Under Curve; Arginine; Biomarkers; Blood Gas Analysis; Blood-Brain Barrier; Capillary Permeability; Carotid Stenosis; Cerebrovascular Circulation; Constriction; Endarterectomy, Carotid; Female; Humans; Jugular Veins; Lactic Acid; Male; Middle Aged; Pilot Projects; Predictive Value of Tests; Prospective Studies; Radial Artery; Reproducibility of Results; Risk Factors; ROC Curve; S100 Calcium Binding Protein beta Subunit; Time Factors; Treatment Outcome

2016
Effect of l-arginine, asymmetric dimethylarginine, and symmetric dimethylarginine on ischemic heart disease risk: A Mendelian randomization study.
    American heart journal, 2016, Volume: 182

    Topics: Arginine; Female; Genome-Wide Association Study; Humans; Male; Mediator Complex; Mendelian Randomization Analysis; Myocardial Infarction; Polymorphism, Single Nucleotide; Transaminases

2016
The role of laser Doppler flowmetry tests, serum angiopoietin-2, asymmetric and symmetric dimethylarginine to predict outcome in chronic kidney disease.
    Journal of hypertension, 2017, Volume: 35, Issue:5

    Topics: Age Factors; Aged; Angiopoietin-2; Arginine; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Diabetes Mellitus; Female; Follow-Up Studies; Humans; Hyperemia; Laser-Doppler Flowmetry; Male; Middle Aged; Multivariate Analysis; Predictive Value of Tests; Proportional Hazards Models; Prospective Studies; Renal Circulation; Renal Insufficiency, Chronic; Risk Assessment; Risk Factors

2017
Admission levels of asymmetric and symmetric dimethylarginine predict long-term outcome in patients with community-acquired pneumonia.
    Respiratory research, 2017, 01-23, Volume: 18, Issue:1

    Topics: Adult; Aged; Arginine; Biomarkers; Community-Acquired Infections; Female; Humans; Longitudinal Studies; Male; Middle Aged; Patient Admission; Pneumonia; Prevalence; Proportional Hazards Models; Risk Assessment; Risk Factors; Survival Analysis; Switzerland

2017
Increased Symmetric Dimethylarginine Level Is Associated with Worse Hospital Outcomes through Altered Left Ventricular Ejection Fraction in Patients with Acute Myocardial Infarction.
    PloS one, 2017, Volume: 12, Issue:1

    Topics: Aged; Arginine; Female; Glomerular Filtration Rate; Heart Failure; Hospitals; Humans; Male; Middle Aged; Myocardial Infarction; Nitric Oxide; Prognosis; Renal Insufficiency, Chronic; Treatment Outcome; Ventricular Function, Left

2017
Investigation of Asymmetric and Symmetric Dimethylarginine Levels after Iloprost Treatment in Patients with Buerger's Disease.
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2017, Volume: 53, Issue:3

    Topics: Adult; Aged; Arginine; Biomarkers; Female; Humans; Iloprost; Infusions, Intravenous; Male; Middle Aged; Thromboangiitis Obliterans; Time Factors; Treatment Outcome; Vasodilator Agents

2017
DdaR (PA1196) Regulates Expression of Dimethylarginine Dimethylaminohydrolase for the Metabolism of Methylarginines in Pseudomonas aeruginosa PAO1.
    Journal of bacteriology, 2017, 04-15, Volume: 199, Issue:8

    Topics: Amidohydrolases; Arginine; Bacterial Proteins; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; omega-N-Methylarginine; Pseudomonas aeruginosa; RNA Polymerase Sigma 54

2017
Endothelial injury in rheumatoid arthritis: a crosstalk between dimethylarginines and systemic inflammation.
    Arthritis research & therapy, 2017, Feb-10, Volume: 19, Issue:1

    Topics: Aged; Arginine; Arthritis, Rheumatoid; Carotid Artery Diseases; Carotid Intima-Media Thickness; Cohort Studies; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunoassay; Inflammation; Laser-Doppler Flowmetry; Male; Middle Aged; Pulse Wave Analysis; Receptor Cross-Talk; Vascular Stiffness

2017
Metabolic profiling of presymptomatic Huntington's disease sheep reveals novel biomarkers.
    Scientific reports, 2017, 02-22, Volume: 7

    Topics: Amino Acids, Branched-Chain; Animals; Animals, Genetically Modified; Area Under Curve; Arginine; Biomarkers; Citrulline; Genotype; Huntington Disease; Logistic Models; Metabolomics; ROC Curve; Sheep

2017
Plasma Arginine/Asymmetric Dimethylarginine Ratio and Incidence of Cardiovascular Events: A Case-Cohort Study.
    The Journal of clinical endocrinology and metabolism, 2017, 06-01, Volume: 102, Issue:6

    Topics: Aged; Arginine; Cardiovascular Diseases; Case-Control Studies; Chromatography, Liquid; Citrulline; Cohort Studies; Female; Humans; Incidence; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; omega-N-Methylarginine; Ornithine; Proportional Hazards Models; Prospective Studies; Risk Factors; Stroke; Tandem Mass Spectrometry

2017
Plasma Symmetric Dimethylarginine Concentration in Dogs with Acute Kidney Injury and Chronic Kidney Disease.
    Journal of veterinary internal medicine, 2017, Volume: 31, Issue:3

    Topics: Acute Kidney Injury; Animals; Arginine; Biomarkers; Case-Control Studies; Creatinine; Dog Diseases; Dogs; Female; Male; Prospective Studies; Renal Insufficiency, Chronic

2017
Symmetric dimethylarginine, high-density lipoproteins and cardiovascular disease.
    European heart journal, 2017, May-21, Volume: 38, Issue:20

    Topics: Aged; Arginine; Biomarkers; Cardiovascular Diseases; Female; Glomerular Filtration Rate; Humans; Lipoproteins, HDL; Male; Middle Aged; Prognosis; Renal Insufficiency, Chronic; Risk Factors

2017
Serum concentrations of symmetric dimethylarginine and creatinine in cats with kidney stones.
    PloS one, 2017, Volume: 12, Issue:4

    Topics: Animals; Arginine; Biomarkers; Cat Diseases; Cats; Chromatography, Liquid; Creatinine; Female; Kidney Calculi; Male; Mass Spectrometry; Renal Insufficiency, Chronic

2017
High asymmetric dimethylarginine, symmetric dimethylarginine and L-arginine levels in migraine patients.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2017, Volume: 38, Issue:7

    Topics: Adult; Arginine; Female; Humans; Male; Middle Aged; Migraine Disorders; Nitric Oxide; Nitric Oxide Synthase Type III; Young Adult

2017
Effect of arginine:lysine and glycine:methionine intake ratios on dyslipidemia and selected biomarkers implicated in cardiovascular disease: A study with hypercholesterolemic rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 91

    Topics: Administration, Oral; Amino Acids; Animals; Arginine; Biomarkers; Body Weight; Cardiovascular Diseases; Dyslipidemias; Glycine; Homocysteine; Hypercholesterolemia; Lipids; Liver; Lysine; Male; Methionine; Nitric Oxide; Organ Size; Rats, Wistar

2017
The Renin-Angiotensin-Aldosterone System in Greyhounds and Non-Greyhound Dogs.
    Journal of veterinary internal medicine, 2017, Volume: 31, Issue:4

    Topics: Albuminuria; Aldosterone; Animals; Arginine; Creatinine; Dogs; Female; Hemodynamics; Male; Peptidyl-Dipeptidase A; Prospective Studies; Renin; Renin-Angiotensin System; Sodium; Species Specificity

2017
Renalase Assessment With Regard to Kidney Function, Lipid Disturbances, and Endothelial Dysfunction Parameters in Stable Renal Transplant Recipients.
    Progress in transplantation (Aliso Viejo, Calif.), 2017, Volume: 27, Issue:2

    Topics: Adult; Antihypertensive Agents; Arginine; C-Reactive Protein; Case-Control Studies; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Creatinine; Cross-Sectional Studies; Endothelium, Vascular; Female; Glomerular Filtration Rate; Hemoglobins; Humans; Hypertension; Intercellular Adhesion Molecule-1; Kidney Transplantation; Male; Middle Aged; Monoamine Oxidase; Renal Insufficiency, Chronic; Severity of Illness Index; Vascular Cell Adhesion Molecule-1

2017
Physical activity - related changes in ADMA and vWF levels in patients with type 2 diabetes: A preliminary study.
    Advances in clinical and experimental medicine : official organ Wroclaw Medical University, 2017, Volume: 26, Issue:4

    Topics: Adult; Arginine; Cholesterol, HDL; Diabetes Mellitus, Type 2; Exercise; Female; Humans; Male; Middle Aged; von Willebrand Factor

2017
Symmetric and asymmetric dimethylarginine as risk markers of cardiovascular disease, all-cause mortality and deterioration in kidney function in persons with type 2 diabetes and microalbuminuria.
    Cardiovascular diabetology, 2017, 07-11, Volume: 16, Issue:1

    Topics: Adult; Aged; Albuminuria; Arginine; Cardiovascular Diseases; Coronary Disease; Creatinine; Diabetes Mellitus, Type 2; Female; Glomerular Filtration Rate; Humans; Kidney; Male; Middle Aged; Risk Factors

2017
Evaluation of serum symmetric dimethylarginine in dogs with heartworm infection.
    Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, 2017, Volume: 81, Issue:3

    Topics: Animals; Arginine; Dirofilariasis; Dog Diseases; Dogs

2017
Cardiomyocyte dimethylarginine dimethylaminohydrolase-1 (DDAH1) plays an important role in attenuating ventricular hypertrophy and dysfunction.
    Basic research in cardiology, 2017, 08-17, Volume: 112, Issue:5

    Topics: Amidohydrolases; Animals; Arginine; Atrial Natriuretic Factor; Disease Models, Animal; Fibrosis; Genetic Predisposition to Disease; Hypertrophy, Left Ventricular; Male; Mice, Knockout; Myocytes, Cardiac; Nitric Oxide; Phenotype; Signal Transduction; Tyrosine; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling

2017
Asymmetric dimethylarginine and symmetric dimethylarginine prospectively relates to carotid wall thickening in black men: the SABPA study.
    Amino acids, 2017, Volume: 49, Issue:11

    Topics: Adult; Arginine; Black People; Cardiovascular Diseases; Carotid Intima-Media Thickness; Follow-Up Studies; Humans; Male; Middle Aged; Prospective Studies; Regression Analysis; South America; White People

2017
Systemic vascular resistance and endogenous inhibitors of nitric oxide synthesis in early- compared to late-onset preeclampsia: preliminary findings.
    Hypertension in pregnancy, 2017, Volume: 36, Issue:3

    Topics: Adult; Arginine; Case-Control Studies; Female; Humans; Pre-Eclampsia; Pregnancy; Vascular Resistance; Young Adult

2017
Asymmetric Dimethylarginine Predicts Long-Term Outcome in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease.
    Lung, 2017, Volume: 195, Issue:6

    Topics: Aged; Aged, 80 and over; Arginine; Biomarkers; Disease Progression; Female; Humans; Male; Middle Aged; Prognosis; Proportional Hazards Models; Pulmonary Disease, Chronic Obstructive; Risk Factors; Severity of Illness Index; Survival Rate; Switzerland; Time Factors

2017
EVALUATION OF SYMMETRIC DIMETHYLARGININE AS AN EARLY BIOMARKER OF CHRONIC KIDNEY DISEASE IN CAPTIVE CHEETAHS (ACINONYX JUBATUS).
    Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2017, Volume: 48, Issue:3

    Topics: Acinonyx; Animals; Animals, Zoo; Arginine; Biomarkers; Creatinine; Female; Male; Reference Values; Renal Insufficiency, Chronic

2017
Serum symmetric dimethylarginine and creatinine in Birman cats compared with cats of other breeds.
    Journal of feline medicine and surgery, 2018, Volume: 20, Issue:10

    Topics: Animals; Arginine; Biomarkers; Cat Diseases; Cats; Creatinine; Female; Male; Pedigree; Reference Values; Renal Insufficiency, Chronic

2018
Spontaneous variability of pre-dialysis concentrations of uremic toxins over time in stable hemodialysis patients.
    PloS one, 2017, Volume: 12, Issue:10

    Topics: Aged; Aged, 80 and over; Analysis of Variance; Arginine; beta 2-Microglobulin; Creatinine; Female; Hemodialysis Solutions; Hippurates; Humans; Indican; Male; Middle Aged; Observer Variation; Phosphorus; Renal Dialysis; Renal Insufficiency, Chronic; Toxins, Biological; Urea; Uric Acid

2017
Opposing effects of rheumatoid arthritis and low dose prednisolone on arginine metabolomics.
    Atherosclerosis, 2017, Volume: 266

    Topics: Administration, Oral; Aged; Arginine; Arthritis, Rheumatoid; Biomarkers; Case-Control Studies; Chromatography, Liquid; Drug Administration Schedule; Endothelium, Vascular; Female; Glucocorticoids; Homoarginine; Humans; Male; Mass Spectrometry; Metabolomics; Middle Aged; Prednisolone; Time Factors; Treatment Outcome

2017
Plasma biomarker discovery for early chronic kidney disease diagnosis based on chemometric approaches using LC-QTOF targeted metabolomics data.
    Journal of pharmaceutical and biomedical analysis, 2018, Feb-05, Volume: 149

    Topics: Adolescent; Age Factors; Arginine; Biomarkers; Child; Child, Preschool; Chromatography, High Pressure Liquid; Citrulline; Creatinine; Early Diagnosis; Female; Glomerular Filtration Rate; Humans; Male; Metabolic Networks and Pathways; Metabolomics; Multivariate Analysis; Renal Insufficiency, Chronic; S-Adenosylmethionine; Sex Factors; Tandem Mass Spectrometry

2018
Symmetric dimethylarginine (SDMA) outperforms asymmetric dimethylarginine (ADMA) and other methylarginines as predictor of renal and cardiovascular outcome in non-dialysis chronic kidney disease.
    Clinical research in cardiology : official journal of the German Cardiac Society, 2018, Volume: 107, Issue:3

    Topics: Aged; Arginine; Biomarkers; Cardiovascular Diseases; Chromatography, Liquid; Disease Progression; Female; Germany; Humans; Incidence; Male; Middle Aged; omega-N-Methylarginine; Prognosis; Renal Dialysis; Renal Insufficiency, Chronic; Risk Assessment; Risk Factors

2018
Contribution of symmetric dimethylarginine to GFR decline in pediatric chronic kidney disease.
    Pediatric nephrology (Berlin, Germany), 2018, Volume: 33, Issue:4

    Topics: Adolescent; Arginine; Child; Child, Preschool; Chromatography, High Pressure Liquid; Disease Progression; Female; Glomerular Filtration Rate; Humans; Infant; Kidney; Male; Mass Spectrometry; Prospective Studies; Renal Insufficiency, Chronic

2018
Symmetric Dimethylarginine in Cats with Hypertrophic Cardiomyopathy and Diabetes Mellitus.
    Journal of veterinary internal medicine, 2018, Volume: 32, Issue:1

    Topics: Animals; Arginine; Biomarkers; Cardiomyopathy, Hypertrophic; Case-Control Studies; Cat Diseases; Cats; Comorbidity; Diabetes Mellitus; Female; Male; Renal Insufficiency, Chronic

2018
Inverse correlation between maternal plasma asymmetric dimethylarginine (ADMA) and birthweight percentile in women with impaired placental perfusion: circulating ADMA as an NO-independent indicator of fetal growth restriction?
    Amino acids, 2018, Volume: 50, Issue:2

    Topics: Adult; Arginine; Biomarkers; Birth Weight; Female; Fetal Growth Retardation; Fetus; Gestational Age; Humans; Infant, Newborn; Male; Nitrates; Nitric Oxide; Nitrites; Placenta; Pre-Eclampsia; Pregnancy; Pregnancy Outcome

2018
Amniotic Fluid Arginine from Gestational Weeks 13 to 15 Is a Predictor of Birth Weight, Length, and Head Circumference.
    Nutrients, 2017, Dec-14, Volume: 9, Issue:12

    Topics: Adult; Amniotic Fluid; Arginine; Birth Weight; Dietary Supplements; Female; Fetal Growth Retardation; Humans; Infant; Male; Middle Aged; Nitric Oxide; Pregnancy; Pregnancy Trimesters; Young Adult

2017
Global arginine bioavailability ratio is decreased in patients with major depressive disorder.
    Journal of affective disorders, 2018, 03-15, Volume: 229

    Topics: Adult; Aged; Arginine; Biological Availability; Citrulline; Depressive Disorder, Major; Female; Humans; Male; Middle Aged; Nitric Oxide; Ornithine; Oxidative Stress; Surveys and Questionnaires; Young Adult

2018
Evaluation of Serum Symmetric Dimethylarginine Concentration as a Marker for Masked Chronic Kidney Disease in Cats With Hyperthyroidism.
    Journal of veterinary internal medicine, 2018, Volume: 32, Issue:1

    Topics: Animals; Arginine; Azotemia; Biomarkers; Cat Diseases; Cats; Female; Glomerular Filtration Rate; Hyperthyroidism; Male; Prospective Studies; Renal Insufficiency, Chronic

2018
Variability of Symmetric Dimethylarginine in Apparently Healthy Dogs.
    Journal of veterinary internal medicine, 2018, Volume: 32, Issue:2

    Topics: Animals; Arginine; Biomarkers; Creatinine; Dogs; Female; Male; Prospective Studies; Reference Values; Reproducibility of Results

2018
Malaria in pregnancy alters l-arginine bioavailability and placental vascular development.
    Science translational medicine, 2018, 03-07, Volume: 10, Issue:431

    Topics: Animals; Arginine; Female; Humans; Malaria; Mice; Nitric Oxide; Placenta; Pregnancy; Pregnancy Outcome; Prospective Studies

2018
Serum concentrations of asymmetric and symmetric dimethylarginine are associated with mortality in acute heart failure patients.
    International journal of cardiology, 2018, 06-15, Volume: 261

    Topics: Acute Disease; Aged; Aged, 80 and over; Arginine; Biomarkers; Cohort Studies; Female; Heart Failure; Humans; Male; Mortality; Stroke Volume

2018
Asymmetric and Symmetric Dimethylarginines are Markers of Delayed Cerebral Ischemia and Neurological Outcome in Patients with Subarachnoid Hemorrhage.
    Neurocritical care, 2018, Volume: 29, Issue:1

    Topics: Adult; Aged; Arginine; Biomarkers; Brain Ischemia; Cerebral Angiography; Female; Humans; Incidence; Male; Middle Aged; Outcome Assessment, Health Care; Subarachnoid Hemorrhage

2018
Alterations in plasma L-arginine and methylarginines in heart failure and after heart transplantation.
    Scandinavian cardiovascular journal : SCJ, 2018, Volume: 52, Issue:4

    Topics: Arginine; Biomarkers; Citrulline; Endothelium, Vascular; Female; Heart Failure; Heart Transplantation; Hemodynamics; Humans; Male; Middle Aged; Nitric Oxide; Ornithine; Prospective Studies; Time Factors; Treatment Outcome

2018
Asymmetric and symmetric dimethylarginines and mortality in patients with hematological malignancies-A prospective study.
    PloS one, 2018, Volume: 13, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Arginine; Biomarkers, Tumor; Case-Control Studies; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; Middle Aged; Prognosis; Prospective Studies; Survival Rate; Young Adult

2018
Elevated levels of plasma symmetric dimethylarginine and increased arginase activity as potential indicators of cardiovascular comorbidity in rheumatoid arthritis.
    Arthritis research & therapy, 2018, 06-08, Volume: 20, Issue:1

    Topics: Aged; Arginase; Arginine; Arthritis, Rheumatoid; Biomarkers; Cardiovascular Diseases; Comorbidity; Female; Humans; Hyperlipidemias; Hypertension; Male; Middle Aged; Prevalence; Risk Factors; United States

2018
Activation of the p53-MDM4 regulatory axis defines the anti-tumour response to PRMT5 inhibition through its role in regulating cellular splicing.
    Scientific reports, 2018, 06-26, Volume: 8, Issue:1

    Topics: Alternative Splicing; Antineoplastic Agents; Arginine; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Cell Survival; Enzyme Inhibitors; Humans; Nuclear Proteins; Protein Isoforms; Protein-Arginine N-Methyltransferases; Proto-Oncogene Proteins; RNA Splicing; snRNP Core Proteins; Tumor Suppressor Protein p53

2018
Novel Markers for Adverse Events in Atrial Fibrillation.
    Journal of the American College of Cardiology, 2018, 08-14, Volume: 72, Issue:7

    Topics: Arginine; Atrial Fibrillation; Biomarkers; Humans

2018
Establishment of reference intervals for serum symmetric dimethylarginine in adult nonracing Greyhounds.
    Veterinary clinical pathology, 2018, Volume: 47, Issue:3

    Topics: Animals; Arginine; Dogs; Female; Male; Reference Values; Species Specificity

2018
Plasma Homoarginine Concentrations According to Use of Hormonal Contraception.
    Scientific reports, 2018, 08-15, Volume: 8, Issue:1

    Topics: Adolescent; Adult; Arginine; Chromatography, Liquid; Contraception; Contraceptives, Oral, Hormonal; Estrogens; Female; Homoarginine; Humans; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Progestins; Tandem Mass Spectrometry; Young Adult

2018
Changes in arginine are inversely associated with type 2 diabetes: A case-cohort study in the PREDIMED trial.
    Diabetes, obesity & metabolism, 2019, Volume: 21, Issue:2

    Topics: Aged; Aged, 80 and over; Arginine; Case-Control Studies; Citrulline; Cohort Studies; Diabetes Mellitus, Type 2; Diet, Fat-Restricted; Diet, Mediterranean; Female; Humans; Incidence; Insulin Resistance; Male; Middle Aged; omega-N-Methylarginine; Ornithine; Risk Factors

2019
Research and diagnostic tool: the symmetric dimethylarginine case-for research use only.
    Veterinary clinical pathology, 2018, Volume: 47, Issue:3

    Topics: Animals; Arginine; Biomarkers; Cat Diseases; Cats; Creatinine; Dog Diseases; Dogs; Renal Insufficiency, Chronic

2018
RETROSPECTIVE ANALYSIS AND VALIDATION OF SERUM SYMMETRIC DIMETHYLARGININE (SDMA) CONCENTRATIONS IN CHEETAHS ( ACINONYX JUBATUS).
    Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2018, Volume: 49, Issue:3

    Topics: Acinonyx; Animals; Arginine; Biomarkers; Female; Male; Reproducibility of Results; Retrospective Studies

2018
Homoarginine/ADMA ratio and homoarginine/SDMA ratio as independent predictors of cardiovascular mortality and cardiovascular events in lower extremity arterial disease.
    Scientific reports, 2018, 09-21, Volume: 8, Issue:1

    Topics: Aged; Arginine; Biomarkers; Cardiovascular Diseases; Cardiovascular System; Female; Homoarginine; Humans; Incidence; Lower Extremity; Male; Middle Aged; Prospective Studies; Risk Factors; Vascular Diseases

2018
Diagnostic value of plasma tryptophan and symmetric dimethylarginine levels for acute kidney injury among tacrolimus-treated kidney transplant patients by targeted metabolomics analysis.
    Scientific reports, 2018, 10-02, Volume: 8, Issue:1

    Topics: Acute Kidney Injury; Adult; Antidepressive Agents, Second-Generation; Arginine; China; Female; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Metabolomics; Middle Aged; Plasma; Retrospective Studies; Sensitivity and Specificity; Tacrolimus; Transplant Recipients; Tryptophan; Young Adult

2018
AGXT2 and DDAH-1 genetic variants are highly correlated with serum ADMA and SDMA levels and with incidence of coronary artery disease in Egyptians.
    Molecular biology reports, 2018, Volume: 45, Issue:6

    Topics: Adult; Amidohydrolases; Arginine; Case-Control Studies; Coronary Artery Disease; Egypt; Female; Genetic Variation; Genotype; Humans; Incidence; Male; Middle Aged; Nitric Oxide; Polymorphism, Single Nucleotide; Transaminases

2018
A preliminary investigation into the prognostic relevance of symmetric dimethylarginine in critically ill dogs.
    Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001), 2018, Volume: 28, Issue:6

    Topics: Acute Kidney Injury; Animals; Arginine; Biomarkers; Case-Control Studies; Critical Illness; Dog Diseases; Dogs; Female; Male; Predictive Value of Tests; Prognosis; Prospective Studies

2018
Renal function and blood pressure in 11 year old children born extremely preterm or small for gestational age.
    PloS one, 2018, Volume: 13, Issue:10

    Topics: Arginine; Blood Pressure; Child; Female; Fetal Growth Retardation; Follow-Up Studies; Glomerular Filtration Rate; Humans; Infant, Extremely Premature; Infant, Small for Gestational Age; Kidney; Male; Prospective Studies

2018
Comparative performance of IDEXX SDMA Test and the DLD SDMA ELISA for the measurement of SDMA in canine and feline serum.
    PloS one, 2018, Volume: 13, Issue:10

    Topics: Animals; Arginine; Cats; Chromatography, High Pressure Liquid; Dogs; Enzyme-Linked Immunosorbent Assay; Linear Models; Prospective Studies; Reagent Kits, Diagnostic; Reproducibility of Results; Tandem Mass Spectrometry

2018
Fearful dogs have increased plasma glutamine and γ-glutamyl glutamine.
    Scientific reports, 2018, 10-29, Volume: 8, Issue:1

    Topics: Animals; Anxiety; Arginine; Behavior, Animal; Biomarkers; Breeding; Dipeptides; Dogs; Fear; Female; Glutamine; Male; Metabolome; Species Specificity

2018
Response to letter to editor regarding Variability of symmetric dimethylarginine in apparently healthy dogs.
    Journal of veterinary internal medicine, 2019, Volume: 33, Issue:1

    Topics: Animals; Arginine; Dog Diseases; Dogs

2019
Variability of symmetric dimethylarginine in apparently healthy dogs.
    Journal of veterinary internal medicine, 2019, Volume: 33, Issue:1

    Topics: Animals; Arginine; Biomarkers; Dog Diseases; Dogs; Kidney Diseases

2019
Evidence for a protective role for the rs805305 single nucleotide polymorphism of dimethylarginine dimethylaminohydrolase 2 (DDAH2) in septic shock through the regulation of DDAH activity.
    Critical care (London, England), 2018, 12-11, Volume: 22, Issue:1

    Topics: Amidohydrolases; Arginine; Biomarkers; Humans; Organ Dysfunction Scores; Polymorphism, Single Nucleotide; Protective Agents; Shock, Septic; Statistics, Nonparametric; Time Factors

2018
Assessment of symmetric dimethylarginine as a biomarker of renal function in hyperthyroid cats treated with radioiodine.
    Journal of veterinary internal medicine, 2019, Volume: 33, Issue:2

    Topics: Animals; Arginine; Biomarkers; Blood Urea Nitrogen; Cat Diseases; Cats; Creatinine; Female; Glomerular Filtration Rate; Hyperthyroidism; Iodine Radioisotopes; Kidney Function Tests; Male; Prospective Studies

2019
Guanidino compound ratios are associated with stroke etiology, internal carotid artery stenosis and CHA
    Journal of the neurological sciences, 2019, 02-15, Volume: 397

    Topics: Aged; Arginine; Biomarkers; Brain Ischemia; Carotid Arteries; Carotid Stenosis; Cross-Sectional Studies; Female; Homoarginine; Humans; Intracranial Hemorrhages; Male; Middle Aged; Recurrence; Stroke

2019
Increased Aqueous Humor Symmetric Dimethylarginine Level in Patients with Primary Open Angle Glaucoma.
    Current eye research, 2019, Volume: 44, Issue:6

    Topics: Aged; Aged, 80 and over; Aqueous Humor; Arginine; Case-Control Studies; Chromatography, High Pressure Liquid; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Prospective Studies; Tandem Mass Spectrometry; Tonometry, Ocular

2019
Changes in thyroid and renal function after bilateral thyroidectomy in cats.
    Journal of veterinary internal medicine, 2019, Volume: 33, Issue:2

    Topics: Animals; Arginine; Azotemia; Body Weight; Cat Diseases; Cats; Creatinine; Cross-Sectional Studies; Hyperthyroidism; Hypothyroidism; Longitudinal Studies; Retrospective Studies; Thyroidectomy; Thyroxine

2019
Comparison of the diagnostic value of symmetric dimethylarginine, cystatin C, and creatinine for detection of decreased glomerular filtration rate in dogs.
    Journal of veterinary internal medicine, 2019, Volume: 33, Issue:2

    Topics: Animals; Arginine; Biomarkers; Case-Control Studies; Creatinine; Cystatin C; Decision Trees; Dog Diseases; Dogs; Female; Glomerular Filtration Rate; Kidney Function Tests; Male; Renal Insufficiency, Chronic; Sensitivity and Specificity

2019
Total methylated arginine load as a risk parameter in subjects with masked hypertension.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2020, Volume: 42, Issue:2

    Topics: Arginine; Biomarkers; Blood Pressure Determination; Female; Humans; Hypertension; Male; Masked Hypertension; Middle Aged; Nitric Oxide; omega-N-Methylarginine; Risk Factors

2020
Asymmetric dimethylarginine as a potential biomarker for management and follow-up of phenylketonuria.
    European journal of pediatrics, 2019, Volume: 178, Issue:6

    Topics: Arginine; Biomarkers; Case-Control Studies; Child; Creatinine; Cross-Sectional Studies; Diet, Protein-Restricted; Female; Humans; Male; Phenylketonurias; Spain

2019
The protective effect of dronedarone on the structure and mechanical properties of the aorta in hypertensive rats by decreasing the concentration of symmetric dimethylarginine (SDMA).
    PloS one, 2019, Volume: 14, Issue:5

    Topics: Animals; Aorta, Thoracic; Arginine; Dronedarone; Hypertension; Male; Microscopy, Confocal; Random Allocation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vascular Remodeling

2019
Asymmetric and Symmetric Protein Arginine Dimethylation: Concept and Postprandial Effects of High-Fat Protein Meals in Healthy Overweight Men.
    Nutrients, 2019, Jun-27, Volume: 11, Issue:7

    Topics: Adult; Arginine; Biomarkers; Diet, High-Fat; Diet, High-Protein; Gas Chromatography-Mass Spectrometry; Humans; Interleukin-6; Male; Middle Aged; Overweight; Postprandial Period; Time Factors; Tumor Necrosis Factor-alpha; Urinalysis; Young Adult

2019
Establishment of reference values for the lysine acetylation marker N
    Amino acids, 2019, Volume: 51, Issue:9

    Topics: Adolescent; Adult; Arginine; Biomarkers; Cardiovascular Diseases; Carnitine; Chromatography, Liquid; Citrulline; Creatinine; Female; Homoarginine; Humans; Lysine; Male; Middle Aged; Ornithine; Reference Values; Renal Insufficiency, Chronic; Tandem Mass Spectrometry; Young Adult

2019
Metabolites of the Nitric Oxide (NO) Pathway Are Altered and Indicative of Reduced NO and Arginine Bioavailability in Patients with Cardiometabolic Diseases Complicated with Chronic Wounds of Lower Extremities: Targeted Metabolomics Approach (LC-MS/MS).
    Oxidative medicine and cellular longevity, 2019, Volume: 2019

    Topics: Aged; Arginine; Cardiovascular Diseases; Case-Control Studies; Chemokines; Citrulline; Cytokines; Female; Growth Hormone; Humans; Lower Extremity; Male; Metabolomics; Middle Aged; Nitric Oxide; Wounds and Injuries

2019
Low homoarginine/SDMA ratio is associated with poor short- and long-term outcome after stroke in two prospective studies.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2020, Volume: 41, Issue:1

    Topics: Arginine; Biomarkers; Cohort Studies; Homoarginine; Humans; Prospective Studies; Stroke; Survival Rate; Treatment Outcome

2020
Symmetric dimethylarginine concentrations in dogs with International Renal Interest Society stage 4 chronic kidney disease undergoing intermittent hemodialysis.
    Journal of veterinary internal medicine, 2019, Volume: 33, Issue:6

    Topics: Animals; Arginine; Dog Diseases; Dogs; Female; Male; Renal Dialysis; Renal Insufficiency, Chronic

2019
Racial Differences in Cardiovascular Biomarkers in the General Population.
    Journal of the American Heart Association, 2019, 09-17, Volume: 8, Issue:18

    Topics: Adiponectin; Adult; Albuminuria; Antibodies, Antinuclear; Arginine; Biomarkers; Black or African American; C-Reactive Protein; Cardiovascular Diseases; Cross-Sectional Studies; Female; Fibrin Fibrinogen Degradation Products; Homoarginine; Humans; Interleukin-1 Receptor-Like 1 Protein; Leptin; Linear Models; Lipoprotein(a); Male; Middle Aged; Multivariate Analysis; Natriuretic Peptide, Brain; Osteoprotegerin; Peptide Fragments; Proportional Hazards Models; Receptor for Advanced Glycation End Products; Troponin T; White People

2019
Targeted metabolomic analysis of nitric oxide/L-arginine pathway metabolites in dementia: association with pathology, severity, and structural brain changes.
    Scientific reports, 2019, 09-24, Volume: 9, Issue:1

    Topics: Arginine; Biomarkers; Brain; Citrulline; Dementia; Female; Humans; Male; Metabolomics; Middle Aged; Nitric Oxide; Signal Transduction

2019
Fibroblast growth factor 23 and symmetric dimethylarginine concentrations in geriatric cats.
    Journal of veterinary internal medicine, 2019, Volume: 33, Issue:6

    Topics: Aging; Animals; Arginine; Biomarkers; Cats; Cross-Sectional Studies; Female; Fibroblast Growth Factors; Male; Reference Values

2019
Changes in Water Soluble Uremic Toxins and Urinary Acute Kidney Injury Biomarkers After 10- and 100-km Runs.
    International journal of environmental research and public health, 2019, 10-28, Volume: 16, Issue:21

    Topics: Acute Kidney Injury; Acute-Phase Proteins; Adult; Albuminuria; Arginine; Biomarkers; Creatinine; Female; Glomerular Filtration Rate; Humans; Lipocalin-2; Lipocalins; Male; Methylamines; Middle Aged; Running; Urea; Uric Acid; Water

2019
Relationship between serum iohexol clearance, serum SDMA concentration, and serum creatinine concentration in non-azotemic dogs.
    Journal of veterinary internal medicine, 2020, Volume: 34, Issue:1

    Topics: Animals; Arginine; Contrast Media; Creatinine; Dog Diseases; Dogs; Glomerular Filtration Rate; Iohexol; Renal Insufficiency, Chronic

2020
Markers of endothelial pathology to support detection of atrial fibrillation in embolic stroke of undetermined source.
    Scientific reports, 2019, 12-19, Volume: 9, Issue:1

    Topics: Aged; Aged, 80 and over; Arginine; Atrial Fibrillation; Biomarkers; Carotid Intima-Media Thickness; Electrocardiography; Embolism; Endothelium; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Risk Factors; ROC Curve; Statistics, Nonparametric; Stroke

2019
Evaluation of serum symmetric dimethylarginine as a biomarker of kidney disease in canine leishmaniosis due to Leishmania infantum.
    Veterinary parasitology, 2020, Volume: 277

    Topics: Animals; Arginine; Azotemia; Biomarkers; Dog Diseases; Dogs; Leishmania infantum; Leishmaniasis, Visceral; Renal Insufficiency, Chronic; Retrospective Studies

2020
A retrospective evaluation of the relationship between symmetric dimethylarginine, creatinine and body weight in hyperthyroid cats.
    PloS one, 2020, Volume: 15, Issue:1

    Topics: Animals; Arginine; Biomarkers; Body Weight; Cats; Creatinine; Diagnostic Tests, Routine; Female; Glomerular Filtration Rate; Hyperthyroidism; Kidney; Male; Renal Insufficiency, Chronic; Retrospective Studies

2020
Symmetric dimethylarginine in dysfunctional high-density lipoprotein mediates endothelial glycocalyx breakdown in chronic kidney disease.
    Kidney international, 2020, Volume: 97, Issue:3

    Topics: Arginine; Cross-Sectional Studies; Endothelial Cells; Glycocalyx; Humans; Lipoproteins, HDL; Renal Insufficiency, Chronic

2020
Plausible diagnostic value of urinary isomeric dimethylarginine ratio for diabetic nephropathy.
    Scientific reports, 2020, 02-19, Volume: 10, Issue:1

    Topics: Adult; Aged; Albuminuria; Arginine; Chromatography, High Pressure Liquid; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Feasibility Studies; Female; Humans; Male; Middle Aged; Predictive Value of Tests; ROC Curve; Tandem Mass Spectrometry

2020
Dysfunctional HDL takes its Toll on the endothelial glycocalyx.
    Kidney international, 2020, Volume: 97, Issue:3

    Topics: Arginine; Glycocalyx; Humans; Lipoproteins, HDL; Renal Insufficiency, Chronic

2020
Symmetric dimethylarginine values in koalas (Phascolarctos cinereus) based on oxalate nephrosis status.
    Australian veterinary journal, 2020, Volume: 98, Issue:6

    Topics: Animals; Arginine; Nephrosis; Oxalates; Phascolarctidae; South Australia

2020
Glomerular filtration rate determined by measuring serum clearance of a single dose of inulin and serum symmetric dimethylarginine concentration in clinically normal cheetahs (
    American journal of veterinary research, 2020, Volume: 81, Issue:4

    Topics: Acinonyx; Animals; Arginine; Creatinine; Diagnostic Tests, Routine; Glomerular Filtration Rate; Inulin

2020
Sexual Dimorphism of Metabolomic Profile in Arterial Hypertension.
    Scientific reports, 2020, 05-05, Volume: 10, Issue:1

    Topics: Adult; Arginine; Biomarkers; Discriminant Analysis; Female; Humans; Hypertension; Least-Squares Analysis; Male; Metabolome; Middle Aged; Ornithine; Phosphatidylcholines; Principal Component Analysis; Sex Factors; Sphingomyelins

2020
Cardiovascular-renal axis disorder and acute-phase proteins in cats with congestive heart failure caused by primary cardiomyopathy.
    Journal of veterinary internal medicine, 2020, Volume: 34, Issue:3

    Topics: Acute-Phase Proteins; Animals; Arginine; Biomarkers; Cardiomyopathies; Case-Control Studies; Cat Diseases; Cats; Creatinine; Female; Heart Failure; Inflammation; Kidney Diseases; Male; Natriuretic Peptide, Brain; Peptide Fragments

2020
Symmetric Dimethylarginine as a Secondary Prevention Biomarker of Chronic Kidney Disease.
    Nephron, 2020, Volume: 144, Issue:6

    Topics: Adult; Arginine; Biomarkers; Humans; Kidney Failure, Chronic; Secondary Prevention

2020
Arginine derivatives in atrial fibrillation progression phenotypes.
    Journal of molecular medicine (Berlin, Germany), 2020, Volume: 98, Issue:7

    Topics: Aged; Arginine; Atrial Fibrillation; Biomarkers; Cohort Studies; Disease Progression; Female; Homoarginine; Humans; Male; Middle Aged; Phenotype

2020
Assessment of serum symmetric dimethylarginine and creatinine concentrations in hyperthyroid cats before and after a fixed dose of orally administered radioiodine.
    Journal of veterinary internal medicine, 2020, Volume: 34, Issue:4

    Topics: Administration, Oral; Animals; Arginine; Cat Diseases; Cats; Cohort Studies; Creatinine; Hyperthyroidism; Iodine Radioisotopes; Prospective Studies; Renal Insufficiency, Chronic; Thyroxine

2020
Increased symmetric dimethylarginine, but not asymmetric dimethylarginine, concentrations are associated with transient myocardial ischemia and predict outcome.
    The Journal of international medical research, 2020, Volume: 48, Issue:6

    Topics: Aged; Arginine; Biomarkers; Coronary Angiography; Coronary Artery Disease; Coronary Vessels; Dipyridamole; Female; Follow-Up Studies; Heart; Heart Function Tests; Humans; Male; Middle Aged; Myocardial Perfusion Imaging; Prospective Studies; Risk Assessment; Tomography, X-Ray Computed

2020
Renal ultrasonographic strain elastography and symmetric dimethylarginine (SDMA) in canine and feline chronic kidney disease.
    The Journal of veterinary medical science, 2020, Aug-19, Volume: 82, Issue:8

    Topics: Animals; Arginine; Blood Urea Nitrogen; Cat Diseases; Cats; Creatinine; Dog Diseases; Dogs; Elasticity Imaging Techniques; Female; Kidney; Male; Renal Insufficiency, Chronic

2020
Biomarkers for chronic kidney disease in dogs: a comparison study.
    The Journal of veterinary medical science, 2020, Aug-28, Volume: 82, Issue:8

    Topics: Animals; Arginine; Biomarkers; Cystatin C; Dog Diseases; Dogs; Female; Male; Renal Insufficiency, Chronic; Sensitivity and Specificity

2020
Association between breed and renal biomarkers of glomerular filtration rate in dogs.
    The Veterinary record, 2020, Nov-14, Volume: 187, Issue:10

    Topics: Age Factors; Animals; Arginine; Biomarkers; Creatinine; Dog Diseases; Dogs; Glomerular Filtration Rate; Pedigree; Renal Insufficiency, Chronic; Retrospective Studies; Risk Factors

2020
Comprehensive arginine metabolomics and peripheral vasodilatory capacity in rheumatoid arthritis: A monocentric cross-sectional study.
    Microvascular research, 2020, Volume: 131

    Topics: Aged; Aged, 80 and over; Arginine; Arthritis, Rheumatoid; Biomarkers; Case-Control Studies; Citrulline; Cross-Sectional Studies; Female; Fingers; Homoarginine; Humans; Italy; Male; Metabolomics; Middle Aged; Vasodilation

2020
Investigation on urinary and serum alpha klotho in dogs with chronic kidney disease.
    BMC veterinary research, 2020, Jul-16, Volume: 16, Issue:1

    Topics: Animals; Arginine; Blood Urea Nitrogen; Creatinine; Dog Diseases; Dogs; Female; Glucuronidase; Klotho Proteins; Male; Phosphorus; Renal Insufficiency, Chronic

2020
Biologic variation of symmetric dimethylarginine and creatinine in clinically healthy cats.
    Veterinary clinical pathology, 2020, Volume: 49, Issue:3

    Topics: Animals; Arginine; Biological Products; Cats; Creatinine; Prospective Studies; Reference Values

2020
Re: Symmetric Dimethylarginine Values in Koalas (Phascolarctos cinereus) Based on Oxalate Nephrosis Status.
    The Journal of urology, 2020, Volume: 204, Issue:4

    Topics: Animals; Arginine; Nephrosis; Oxalates; Phascolarctidae

2020
Increased Serum Levels of Asymmetric Dimethylarginine and Symmetric Dimethylarginine and Decreased Levels of Arginine in Sudanese Patients with Essential Hypertension.
    Kidney & blood pressure research, 2020, Volume: 45, Issue:5

    Topics: Aged; Arginine; Case-Control Studies; Essential Hypertension; Female; Humans; Male; Middle Aged; Sudan

2020
Symmetric dimethylarginine in dogs with myxomatous mitral valve disease at various stages of disease severity.
    PloS one, 2020, Volume: 15, Issue:9

    Topics: Animals; Arginine; Biomarkers; Case-Control Studies; Dog Diseases; Dogs; Echocardiography; Female; Heart Failure; Heart Valve Diseases; Hypertension, Pulmonary; Male; Mitral Valve; Mitral Valve Insufficiency; Mitral Valve Prolapse; Retrospective Studies; Severity of Illness Index

2020
Symmetric dimethylarginine concentrations in dogs with hypothyroidism before and after treatement with levothyroxine.
    The Journal of small animal practice, 2021, Volume: 62, Issue:2

    Topics: Animals; Arginine; Creatinine; Dog Diseases; Dogs; Hypothyroidism; Thyroxine

2021
Increased Intraplatelet ADMA Level May Promote Platelet Activation in Diabetes Mellitus.
    Oxidative medicine and cellular longevity, 2020, Volume: 2020

    Topics: Adenosine Diphosphate; Adult; Aged; Arginine; Blood Platelets; Calcium; Case-Control Studies; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Female; Humans; Male; Mass Spectrometry; Middle Aged; Nitric Oxide; Platelet Activation; Platelet Aggregation; Risk Factors

2020
Serum symmetric dimethylarginine concentration in healthy horses and horses with acute kidney injury.
    BMC veterinary research, 2020, Oct-20, Volume: 16, Issue:1

    Topics: Acute Kidney Injury; Age Factors; Animals; Arginine; Biomarkers; Body Weight; Creatinine; Female; Horse Diseases; Horses; Male; Reference Values; Urea

2020
Rapid Resolution of Non-Effusive Feline Infectious Peritonitis Uveitis with an Oral Adenosine Nucleoside Analogue and Feline Interferon Omega.
    Viruses, 2020, 10-27, Volume: 12, Issue:11

    Topics: Adenosine; Animals; Antiviral Agents; Arginine; Cats; Coronavirus, Feline; Feline Infectious Peritonitis; Glycoproteins; Interferon Type I; Male; Nucleosides; Uveitis

2020
Risk of Development of Chronic Kidney Disease After Exposure to Borrelia burgdorferi and Anaplasma spp.
    Topics in companion animal medicine, 2021, Volume: 42

    Topics: Anaplasma; Animals; Arginine; Borrelia burgdorferi; Creatinine; Dog Diseases; Dogs; Ehrlichiosis; Lyme Disease; Renal Insufficiency, Chronic; Retrospective Studies

2021
Urinary clusterin and cystatin B as biomarkers of tubular injury in dogs following envenomation by the European adder.
    Research in veterinary science, 2021, Volume: 134

    Topics: Acute Kidney Injury; Animals; Arginine; Biomarkers; Case-Control Studies; Clusterin; Cohort Studies; Creatinine; Cystatin B; Dog Diseases; Dogs; Female; Kidney Function Tests; Male; Prospective Studies; Retrospective Studies; Snake Bites; Viperidae

2021
Asymmetric dimethylarginine-A potential cardiac biomarker in horses.
    Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology, 2021, Volume: 33

    Topics: Animals; Arginine; Biomarkers; Enzyme-Linked Immunosorbent Assay; Female; Heart Diseases; Horse Diseases; Horses; Male; Prospective Studies; Reference Values

2021
Evaluation of Biomarkers in Sepsis: High Dimethylarginine (ADMA and SDMA) Concentrations Are Associated with Mortality.
    The journal of applied laboratory medicine, 2021, 04-29, Volume: 6, Issue:3

    Topics: Arginine; Biomarkers; Humans; Sepsis

2021
Detecting acute kidney injury in horses by measuring the concentration of symmetric dimethylarginine in serum.
    Acta veterinaria Scandinavica, 2021, Jan-15, Volume: 63, Issue:1

    Topics: Acute Kidney Injury; Animals; Arginine; Biomarkers; Female; Horse Diseases; Horses; Male; Predictive Value of Tests

2021
Intrathecal and systemic alterations of L-arginine metabolism in patients after intracerebral hemorrhage.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2021, Volume: 41, Issue:8

    Topics: Aged; Arginine; Case-Control Studies; Cerebral Hemorrhage; Chromatography, High Pressure Liquid; Citrulline; Female; Humans; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Ornithine; Risk Factors; Tandem Mass Spectrometry; Up-Regulation

2021
Analytical quality performance goals for symmetric dimethylarginine in cats.
    Veterinary clinical pathology, 2021, Volume: 50, Issue:1

    Topics: Animals; Arginine; Biomarkers; Creatinine; Dog Diseases; Dogs; Goals; Renal Insufficiency, Chronic

2021
Symmetric dimethylarginine and creatinine concentrations in serum of healthy draft horses.
    Journal of veterinary internal medicine, 2021, Volume: 35, Issue:2

    Topics: Animals; Arginine; Biomarkers; Cat Diseases; Cats; Creatinine; Cross-Sectional Studies; Dog Diseases; Dogs; Horse Diseases; Horses; Renal Insufficiency, Chronic

2021
Lack of evidence of the correlation between plasma Asymmetrical Dimethylarginine correlation and IMT in type 2 diabetic patients with chronic vascular complication.
    Acta biochimica Polonica, 2021, Feb-05, Volume: 68, Issue:1

    Topics: Adult; Aged; Arginine; Atherosclerosis; Carotid Artery, Internal; Carotid Intima-Media Thickness; Case-Control Studies; Chronic Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Humans; Male; Middle Aged; Risk Factors; Ultrasonography, Doppler, Color

2021
Comparison of serum and plasma SDMA measured with point-of-care and reference laboratory analysers: implications for interpretation of SDMA in cats.
    Journal of feline medicine and surgery, 2021, Volume: 23, Issue:10

    Topics: Animals; Arginine; Biomarkers; Cat Diseases; Cats; Dog Diseases; Dogs; Laboratories; Point-of-Care Systems

2021
Is there a relation between serum methylarginine levels and infertility?
    Hormone molecular biology and clinical investigation, 2021, Jan-27, Volume: 42, Issue:3

    Topics: Adult; Arginine; Biomarkers; Disease Susceptibility; Humans; Infertility; Male; Oligospermia; ROC Curve; Semen Analysis; Sperm Count; Young Adult

2021
Serum symmetric dimethylarginine shows a relatively consistent long-term concentration in healthy dogs with a significant effect of increased body fat percentage.
    PloS one, 2021, Volume: 16, Issue:2

    Topics: Adipose Tissue; Animals; Arginine; Biomarkers; Body Composition; Creatinine; Dog Diseases; Dogs; Female; Glomerular Filtration Rate; Male

2021
Altered methylarginine levels after surgery in subjects with multinodular goiter.
    Hormone molecular biology and clinical investigation, 2021, Feb-22, Volume: 42, Issue:3

    Topics: Adult; Arginine; Biomarkers; Case-Control Studies; Chromatography, High Pressure Liquid; Female; Goiter, Nodular; Humans; Male; Middle Aged; omega-N-Methylarginine; Postoperative Period; Sensitivity and Specificity

2021
Whole-body arginine dimethylation is associated with all-cause mortality in adult renal transplant recipients.
    Amino acids, 2021, Volume: 53, Issue:4

    Topics: Adult; Aged; Arginine; Biomarkers; Cardiovascular Diseases; Cause of Death; Female; Heart Disease Risk Factors; Humans; Kidney Transplantation; Male; Methylation; Middle Aged; Protein Processing, Post-Translational; Tissue Donors; Transplant Recipients

2021
Electrophoretic Determination of Symmetric and Asymmetric Dimethylarginine in Human Blood Plasma with Whole Capillary Sample Injection.
    International journal of molecular sciences, 2021, Mar-15, Volume: 22, Issue:6

    Topics: Acetonitriles; Anions; Arginine; Electric Conductivity; Electrophoresis, Capillary; Humans; Limit of Detection

2021
Serial serum creatinine, SDMA and urinary acute kidney injury biomarker measurements in dogs envenomated by the European adder (Vipera berus).
    BMC veterinary research, 2021, Apr-12, Volume: 17, Issue:1

    Topics: Acute Kidney Injury; Animals; Arginine; Biomarkers; Creatinine; Dog Diseases; Dogs; Female; Male; Snake Bites; Viperidae

2021
Evaluation of symmetric dimethylarginine and creatinine in dogs with primary hypoadrenocorticism receiving long-term mineralocorticoid replacement therapy.
    The Veterinary record, 2022, Volume: 190, Issue:1

    Topics: Addison Disease; Animals; Arginine; Creatinine; Dog Diseases; Dogs; Mineralocorticoids

2022
Myelocytomatosis-Protein Arginine N-Methyltransferase 5 Axis Defines the Tumorigenesis and Immune Response in Hepatocellular Carcinoma.
    Hepatology (Baltimore, Md.), 2021, Volume: 74, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Alkylating Agents; Animals; Arginine; Carcinogenesis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p27; Diethylnitrosamine; Enzyme Inhibitors; Female; Histocompatibility Antigens Class II; Humans; Immune Checkpoint Inhibitors; Liver Neoplasms; Liver Neoplasms, Experimental; Lymphocytes, Tumor-Infiltrating; Male; Mice; Mice, Transgenic; Middle Aged; Protein-Arginine N-Methyltransferases; Proto-Oncogene Proteins c-myc; Pyrimidines; Quinolines; Up-Regulation; Young Adult

2021
Elevated serum SDMA and ADMA at hospital admission predict in-hospital mortality of COVID-19 patients.
    Scientific reports, 2021, 05-10, Volume: 11, Issue:1

    Topics: Aged; Aged, 80 and over; Arginine; Biomarkers; Cohort Studies; COVID-19; Female; Hospital Mortality; Hospitalization; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Risk Factors; SARS-CoV-2

2021
Evaluation of serum neutrophil gelatinase-associated lipocalin (NGAL), asymmetric dimethylarginine (ADMA) and symmetric dimethylarginine (SDMA) levels, and their relations with disease type and activity in inflammatory bowel diseases
    Turkish journal of medical sciences, 2021, 10-21, Volume: 51, Issue:5

    Topics: Adult; Aged; Arginine; Biomarkers; Colitis, Ulcerative; Crohn Disease; Female; Humans; Inflammatory Bowel Diseases; Lipocalin-2; Male; Middle Aged

2021
L-arginine, asymmetric and symmetric dimethylarginine for early outcome prediction in unselected cardiac arrest victims: a prospective cohort study.
    Internal and emergency medicine, 2022, Volume: 17, Issue:2

    Topics: Adult; Aged; Arginine; Biomarkers; Female; Heart Arrest; Humans; Male; Prognosis; Prospective Studies

2022
COMPARISON OF BLOOD SYMMETRIC DIMETHYLARGININE AND CREATININE AS ENDOGENOUS MARKERS OF KIDNEY FUNCTION IN CAPTIVE TIGERS (
    Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2021, Volume: 52, Issue:2

    Topics: Animals; Arginine; Biomarkers; Creatinine; Kidney; Renal Insufficiency, Chronic; Retrospective Studies; Tigers

2021
Serum Symmetric Dimethylarginine Concentration in Greyhound Pups and Adults.
    Topics in companion animal medicine, 2021, Volume: 45

    Topics: Animals; Arginine; Dogs; Records

2021
Longitudinal evaluation of symmetric dimethylarginine and concordance of kidney biomarkers in cats and dogs.
    Veterinary journal (London, England : 1997), 2021, Volume: 276

    Topics: Animals; Arginine; Biomarkers; Cat Diseases; Cats; Dog Diseases; Dogs; Kidney; Renal Insufficiency, Chronic; Retrospective Studies

2021
Serum L-arginine and endogenous methylarginine concentrations predict irritable bowel syndrome in adults: A nested case-control study.
    United European gastroenterology journal, 2021, Volume: 9, Issue:7

    Topics: Aged; Aged, 80 and over; Arginine; Biomarkers; Case-Control Studies; Cohort Studies; Female; Humans; Irritable Bowel Syndrome; Logistic Models; Male; Middle Aged; Nitric Oxide; Odds Ratio; Psychological Distress; ROC Curve

2021
Evaluation of symmetric dimethylarginine and Doppler ultrasonography in the diagnosis of gentamicin-induced acute kidney injury in dogs.
    Environmental science and pollution research international, 2022, Volume: 29, Issue:6

    Topics: Acute Kidney Injury; Animals; Arginine; Dogs; Gentamicins; Ultrasonography, Doppler

2022
Associations of circulating dimethylarginines with the metabolic syndrome in the Framingham Offspring study.
    PloS one, 2021, Volume: 16, Issue:9

    Topics: Arginine; Biomarkers; Cross-Sectional Studies; Female; Humans; Male; Metabolic Syndrome; Middle Aged; Prevalence; Prospective Studies; Tandem Mass Spectrometry

2021
Serum symmetric dimethylarginine concentration in healthy neonatal Thoroughbred foals.
    Equine veterinary journal, 2022, Volume: 54, Issue:5

    Topics: Acute Kidney Injury; Animals; Arginine; Biomarkers; Creatinine; Cross-Sectional Studies; Female; Horse Diseases; Horses; Humans; Renal Insufficiency, Chronic

2022
Symmetric Dimethylarginine Is a Sensitive Biomarker of Glomerular Injury in Rats.
    Toxicologic pathology, 2022, Volume: 50, Issue:2

    Topics: Animals; Arginine; Biomarkers; Cat Diseases; Cats; Dog Diseases; Dogs; Male; Rats; Rats, Sprague-Dawley; Renal Insufficiency, Chronic

2022
USE OF SYMMETRIC DIMETHYLARGININE TO DETECT RENAL LESIONS IN FISH: A PRELIMINARY STUDY IN BROOK TROUT (
    Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2021, Volume: 52, Issue:3

    Topics: Animals; Arginine; Kidney; Reference Values; Trout

2021
Symmetric dimethylarginine concentrations in healthy neonatal foals and mares.
    Journal of veterinary internal medicine, 2021, Volume: 35, Issue:6

    Topics: Animals; Arginine; Biomarkers; Female; Glomerular Filtration Rate; Horses; Parturition; Pregnancy

2021
Characterization of the L-Arginine/Nitric Oxide Pathway and Oxidative Stress in Pediatric Patients with Atopic Diseases.
    International journal of molecular sciences, 2022, Feb-15, Volume: 23, Issue:4

    Topics: Arginine; Asthma; Child; Dermatitis, Atopic; Female; Homoarginine; Humans; Male; Malondialdehyde; Nitrates; Nitric Oxide; Nitrites; Oxidative Stress; Signal Transduction

2022
METHOD COMPARISON FOR MEASUREMENT OF SYMMETRIC DIMETHYLARGININE IN TIGERS (
    Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2022, Volume: 53, Issue:1

    Topics: Animals; Arginine; Chromatography, Liquid; Tandem Mass Spectrometry; Tigers

2022
Evaluation of Renal Biomarkers, Including Symmetric Dimethylarginine, following Gentamicin-Induced Proximal Tubular Injury in the Rat.
    Kidney360, 2022, 02-24, Volume: 3, Issue:2

    Topics: Animals; Arginine; Biomarkers; Dog Diseases; Dogs; Gentamicins; Kidney; Rats; Renal Insufficiency, Chronic

2022
High concentration of symmetric dimethylarginine is associated with low platelet reactivity and increased bleeding risk in patients with acute coronary syndrome.
    Thrombosis research, 2022, Volume: 213

    Topics: Acute Coronary Syndrome; Adenosine Diphosphate; Arginine; Biomarkers; Female; Hemorrhage; Humans; Male; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors

2022
Design and validation of an LC-MS/MS method for simultaneous quantification of asymmetric dimethylguanidino valeric acid, asymmetric dimethylarginine and symmetric dimethylarginine in human plasma.
    Pathology, 2022, Volume: 54, Issue:5

    Topics: Arginine; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Chromatography, Liquid; Female; Humans; Male; Non-alcoholic Fatty Liver Disease; Tandem Mass Spectrometry

2022
Evaluation of renal injury and function biomarkers, including symmetric dimethylarginine (SDMA), in the rat passive Heymann nephritis (PHN) model.
    PloS one, 2022, Volume: 17, Issue:5

    Topics: Animals; Arginine; Biomarkers; Creatinine; Cystatin C; Dogs; Glomerulonephritis, Membranous; Kidney; Lipocalin-2; Nitrogen; Rats; Sheep

2022
The association between symmetric dimethylarginine concentrations and various neoplasms in dogs and cats.
    Veterinary and comparative oncology, 2022, Volume: 20, Issue:4

    Topics: Animals; Arginine; Biomarkers; Case-Control Studies; Cat Diseases; Cats; Dog Diseases; Dogs; Neoplasms; Retrospective Studies

2022
Evaluation of symmetric dimethylarginine in cats with acute kidney injury and chronic kidney disease.
    Journal of veterinary internal medicine, 2022, Volume: 36, Issue:5

    Topics: Acute Kidney Injury; Animals; Arginine; Biomarkers; Cat Diseases; Cats; Creatinine; Dog Diseases; Dogs; Humans; Renal Insufficiency, Chronic; Retrospective Studies

2022
Extracellular 5'-methylthioadenosine inhibits intracellular symmetric dimethylarginine protein methylation of FUSE-binding proteins.
    The Journal of biological chemistry, 2022, Volume: 298, Issue:9

    Topics: Arginine; Deoxyadenosines; DNA-Binding Proteins; Humans; Methionine; Methylation; Polyamines; Protein-Arginine N-Methyltransferases; Purine-Nucleoside Phosphorylase; RNA-Binding Proteins; Sequence Deletion; Thionucleosides

2022
The Association Between Uric Acid and Symmetric Dimethylarginine Levels in Patients Undergoing Continuous Ambulatory Peritoneal Dialysis.
    Acta medica Indonesiana, 2022, Volume: 54, Issue:3

    Topics: Arginine; Cardiovascular Diseases; Female; Humans; Lactation; Peritoneal Dialysis, Continuous Ambulatory; Renal Dialysis; Uric Acid; Young Adult

2022
Asymmetric and symmetric dimethylarginine gingival crevicular fluid levels in periodontitis.
    Journal of periodontal research, 2023, Volume: 58, Issue:2

    Topics: Arginine; Chromatography, Liquid; Gingival Crevicular Fluid; Humans; Periodontitis; Tandem Mass Spectrometry

2023
Association of serum ADMA, SDMA and L-NMMA concentrations with disease progression in COVID-19 patients.
    Biochemia medica, 2023, Feb-15, Volume: 33, Issue:1

    Topics: Arginine; COVID-19; Disease Progression; Humans; omega-N-Methylarginine

2023
Urinary excretion of asymmetric (ADMA) and symmetric (SDMA) dimethylarginine is positively related to nitric oxide level in tissues of normotensive and hypertensive rats.
    Amino acids, 2023, Volume: 55, Issue:4

    Topics: Animals; Arginine; Chromatography, Liquid; Citrulline; Hypertension; Male; Nitric Oxide; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tandem Mass Spectrometry

2023
Comparison of serum creatinine, point-of-care symmetric dimethylarginine and renal imaging with glomerular filtration rate measured by renal scintigraphy in healthy and early chronic kidney diseased cats.
    Veterinary research communications, 2023, Volume: 47, Issue:4

    Topics: Animals; Arginine; Biomarkers; Cat Diseases; Cats; Creatinine; Glomerular Filtration Rate; Kidney; Point-of-Care Systems; Radionuclide Imaging; Renal Insufficiency, Chronic

2023
Adult chicken hens (Gallus gallus) have measurable circulating plasma symmetric dimethylarginine via liquid chromatography-tandem mass spectrometry.
    American journal of veterinary research, 2023, Sep-01, Volume: 84, Issue:9

    Topics: Animals; Arginine; Chickens; Chromatography, Liquid; Female; Tandem Mass Spectrometry

2023
Diurnal Variation of L-Arginine and the Cardiovascular Risk Markers Asymmetric and Symmetric Dimethylarginine and Homoarginine in Rotating Night Shift Workers and Controls.
    Biomolecules, 2023, 08-22, Volume: 13, Issue:9

    Topics: Amino Acids; Arginine; Cardiovascular Diseases; Heart Disease Risk Factors; Homoarginine; Humans; Hydrocortisone; Melatonin; Risk Factors

2023
Association of Asymmetric and Symmetric Dimethylarginine with Inflammation in the Population-Based Study of Health in Pomerania.
    Biomolecules, 2023, Nov-04, Volume: 13, Issue:11

    Topics: Arginine; Biomarkers; C-Reactive Protein; Cytokines; Fibrinogen; Humans; Inflammation

2023