arginine has been researched along with substance p in 138 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (5.80) | 18.7374 |
| 1990's | 114 (82.61) | 18.2507 |
| 2000's | 13 (9.42) | 29.6817 |
| 2010's | 2 (1.45) | 24.3611 |
| 2020's | 1 (0.72) | 2.80 |
| Authors | Studies |
|---|---|
| Adachi, H; Akaji, K; Akazawa, Y; Fujii, N; Funakoshi, S; Mitani, K; Oishi, M; Yajima, H | 1 |
| Arden, WA; Fiscus, RR; Gross, DR; Hao, H; Maley, RH; Salley, RK; Wang, X | 1 |
| Lewis, MJ; Siney, L | 2 |
| Beny, JL; Pacicca, C; von der Weid, PY | 1 |
| Busija, DW; Chen, J | 1 |
| Bray, K; Quast, U | 1 |
| de Nucci, G; Mitchell, JA; Vane, JR; Warner, TD | 1 |
| Hersh, LB; Kim, YA; Quay, T; Shriver, B | 1 |
| Bény, JL; von der Weid, PY | 1 |
| Connor, HE; Feniuk, W; Stubbs, CM; Waldron, GJ | 1 |
| Cocks, T; Crack, P | 1 |
| Burnstock, G; Vials, A | 1 |
| Lang, D; Smith, JA | 1 |
| Chester, AH; Moncada, S; O'Neil, GS; Tadjkarimi, S; Yacoub, MH | 1 |
| Okamura, T; Toda, N | 2 |
| Gustafsson, LE; Moncada, S; Persson, MG; Wiklund, CU; Wiklund, NP | 1 |
| Breese, KR; Heistad, DD; Lopez, JA; Mügge, A; Piegors, DJ | 1 |
| Chester, AH; Moncada, S; O'Neil, GS; Palmer, RM; Tadjkarimi, S; Yacoub, MH | 1 |
| Brain, SD; Hughes, SR; Williams, TJ | 1 |
| Allen, SP; Chester, AH; Khagani, A; Luu, TN; Musumeci, F; O'Neil, GS; Ridley, P; Tadjkarimi, S; Yacoub, MH | 1 |
| Förster, S; Schrör, K; Woditsch, I | 1 |
| Whittle, BJ | 1 |
| Nyberg, F; Silberring, J | 1 |
| Gustafsson, LE; Hedqvist, P; Persson, MG | 1 |
| Cornaglia-Ferraris, P; Cornara, L; Melodia, A | 1 |
| Kai, M; Ohkura, Y; Ohno, M | 1 |
| Lopez-Belmonte, J; Rees, DD; Whittle, BJ | 1 |
| Devillier, P; Drapeau, G; Regoli, D; Renoux, M | 1 |
| Chang, MM; Leeman, SE | 1 |
| Muramatsu, I; Sofuku, S; Torigoe, K | 1 |
| Ishida, T; Kawanishi, K; Machida, S; Nishina, Y; Ofuji, T; Sakura, N; Yamamoto, S; Yanaihara, N | 1 |
| Domer, FR; Hellstrom, WJ; Kadowitz, PJ; Sikka, SC; Wang, R | 1 |
| Archer, SL; Hampl, V; Nelson, DP; Weir, EK | 1 |
| Lot, TY; Wilson, VG | 1 |
| Brandes, RP; Dwenger, A; Mügge, A | 1 |
| Archer, SL; Hampl, V; Isaacson, TC; Nelson, DP; Weir, EK | 1 |
| Grider, JR; Jin, JG | 1 |
| Bény, JL; Chabaud, F; Danna, M | 1 |
| Casino, PR; Kilcoyne, CM; Panza, JA; Quyyumi, AA | 1 |
| Enokibori, M; Okamura, T; Toda, N | 1 |
| Bassirat, M; Dusting, GJ; Helme, RD; Khalil, Z; Ralevic, V | 1 |
| Garrison, EA; Kadowitz, PJ; Santiago, JA | 1 |
| Cheng, DY; DeWitt, BJ; Kadowitz, PJ; McMahon, TJ | 1 |
| Barnes, PJ; Belvisi, MG; Fox, AJ; Ward, JK | 1 |
| Arden, WA; Fiscus, RR; Gross, DR; Lanzo, S; Maley, RH; Salley, RK | 1 |
| Beck, JK; Kojda, G; Meyer, W; Noack, E | 1 |
| Cocks, TM; Kilpatrick, EV | 1 |
| Björkman, R; Hallman, KM; Hedner, J; Hedner, T; Henning, M | 1 |
| Holzer, P; Jocic, M | 1 |
| Amerini, S; Geppetti, P; Granger, HJ; Ledda, F; Maggi, CA; Masini, E; Morbidelli, L; Ziche, M | 1 |
| Coderre, TJ; Yashpal, K | 1 |
| Kitto, KF; Kreeger, JS; Larson, AA | 1 |
| Edwall, L; Kerezoudis, NP; Olgart, L | 2 |
| Belova, N; Diaz, MC; Duvilanski, BH; Lasaga, M; McCann, SM; Pisera, D; Rettori, V; Seilicovich, A; Zambruno, C | 1 |
| Beard, RW; Burnstock, G; Loesch, A; Stones, RW | 1 |
| Brett, SE; Chowienczyk, PJ; Cockcroft, JR; Ritter, JM | 1 |
| Brain, SD; Hall, JM | 1 |
| Giuliani, S; Maggi, CA; Zagorodnyuk, V | 1 |
| Brain, SD; Kajekar, R; Moore, PK | 1 |
| Heinemann, A; Holzer, P; Jocic, M; Wachter, C | 1 |
| Gustafsson, LE; Iversen, HH; Wiklund, NP | 1 |
| Cho, CH; Ko, JK; Tang, XL | 1 |
| Calignano, A; Mancuso, F; Sorrentino, L | 1 |
| Damas, J | 1 |
| Brutsaert, DL; Mohan, P; Sys, SU | 1 |
| Ansay, M; Delaunois, A; Gustin, P | 1 |
| Kobayashi, D; Okabe, E; Ozono, S; Todoki, K | 1 |
| Giachetti, A; Maggi, CA; Santicioli, P; Zagorodnyuk, V | 1 |
| Benrath, J; Eschenfelder, C; Gillardon, F; Zimmerman, M | 1 |
| Brain, SD; Cambridge, H | 1 |
| Kinoshita, M; Matsumoto, T; Toda, N | 1 |
| Adams, HR; Parker, JL | 1 |
| Jain, B; Leise, KL; Robbins, RA; Rubinstein, I; Sisson, JH | 1 |
| Hata, F; Kanada, A; Suthamnatpong, N; Takeuchi, T; Yagasaki, O | 1 |
| Grider, JR; Jin, JG; Makhlouf, GM; Misra, S | 1 |
| Henry, JL; Radhakrishnan, V | 1 |
| Giuliani, S; Maggi, CA; Santicioli, P | 1 |
| Nelson, GH; Rosenblum, WI; Shimizu, T | 1 |
| Oyama, H; Satoh, S; Shibuya, M; Suzuki, Y; Takayasu, M | 1 |
| Hattori, K; Kobayashi, Y; Moritake, K; Ohta, F; Shimoura, K; Shinozuka, K | 1 |
| Maher, JW; Murray, J; Richardson, K; Sandler, AD; Schmidt, C | 1 |
| Kani, K; Kitamura, Y; Okamura, T; Toda, N | 1 |
| Egashira, K; Fukai, T; Hata, H; Numaguchi, K; Ohara, Y; Takahashi, T; Takeshita, A; Tomoike, H | 1 |
| Calignano, A; Mancuso, F; Persico, P; Sorrentino, L | 1 |
| Giuliani, S; Maggi, CA; Meini, S; Patacchini, R | 1 |
| Coleman, HA; Parkington, HC; Tare, M; Tonta, MA | 1 |
| Davison, JS; Mathison, R | 1 |
| Gustafsson, LE; Wiklund, CU; Wiklund, NP | 1 |
| Henry, JL; Hui-Chan, CW; Radhakrishnan, V; Yashpal, K | 1 |
| Gao, XP; Jaffe, HA; Olopade, CO; Rubinstein, I | 1 |
| Kondo, M; Konno, K; Sakai, A; Takemura, H; Tamaoki, J | 1 |
| Canton, M; Gully, D; Kitabgi, P; Le Fur, G; Lespy, L; Maffrand, JP; Rostène, W | 1 |
| Aoki, H; Kanaide, H; Kobayashi, S; Kuroiwa, M; Nishimura, J | 1 |
| Dusting, GJ; Helme, RD; Khalil, Z; Ralevic, V | 1 |
| Bult, A; Cui, H; Reubsaet, JL | 1 |
| Hamdad, N; Lavallée, M; Ming, Z; Parent, R | 1 |
| Matsuda, H; Miyatake, K; Nagata, S; Ohmori, F; Uematsu, M | 1 |
| Antunes, E; de Nucci, G; Grassi-Kassisse, DM; Withrington, PG | 1 |
| Kondo, M; Konno, K; Sakai, A; Tagaya, E; Takemura, H; Tamaoki, J | 1 |
| Giuliani, S; Maggi, CA | 1 |
| Hirooka, Y; Imaizumi, T; Takeshita, A | 1 |
| Goettl, VM; Larson, AA | 1 |
| Endoh, N; Ichinose, M; Ishikawa, J; Kageyama, N; Miura, M; Ohuchi, Y; Shirato, K; Tomaki, M | 1 |
| Endo, T; Hironaga, K; Hirooka, Y; Imaizumi, T; Namba, T; Oyama, J; Shiramoto, M; Takeshita, A | 1 |
| Drexler, H; Kästner, S; Paulus, WJ; Shah, AM; Vanderheyden, M | 1 |
| Didion, SP; Mayhan, WG | 1 |
| Mayhan, WG | 1 |
| Carrier, M; Dupuis, J; Mathieu, P; Pelletier, LC; Ryan, J | 1 |
| Champion, HC; DeWitt, BJ; Giles, TD; Greenberg, SS; Kadowitz, PJ; Marrone, JR; McNamara, DB | 1 |
| Bonham, AC; Joad, JP; Kott, KS | 1 |
| Franke, P; Kasheverov, IE; Tsetlin, VI; Utkin, YN | 1 |
| Bagarozzi, DA; Potempa, J; Travis, J | 1 |
| Itzev, D; Ivancheva, C; Lolova, I; Radomirov, R | 1 |
| Bernillon, J; Louis, D; Wallach, JM | 1 |
| Crake, T; Davies, GJ; Katsimaglis, G; Stefanadis, C; Tentolouris, C; Tousoulis, D; Toutouzas, P | 2 |
| Bush, A; Collins, P; Kelleher, A; Li, J; Morgan, C; Penny, DJ; Redington, AN; Rigby, ML; Schulze-Neick, I; Shinebourne, EA | 1 |
| Ikeda, T; Minakata, H; Nomoto, K | 1 |
| Caldwell, RW; Ganapathy, V; Jin, L; Kaesemeyer, WH; Leibach, FH; Ogonowski, AA | 1 |
| Beijnen, JH; Belshof, EH; Bouyakhrichan, M; Bult, A; Hop, E; Kellekule, Y; Reubsaet, JL; Teeuwsen, J; Underberg, WJ; van Maanen, RJ | 1 |
| Dreshaj, IA; Ferkol, T; Haxhiu, MA; Kelley, TJ; Martin, RJ; Mhanna, MJ; van Heeckeren, AM | 1 |
| Tiefenbacher, CP | 1 |
| Gonon, A; Gourine, A; Pernow, J; Sjöquist, PO | 1 |
| Hori, M; Karaki, H; Murata, T; Ozaki, H; Sato, K; Yamawaki, H | 1 |
| Calignano, A; Di Pierro, P; Esposito, C; Mancuso, F; Porta, R; Sommella, MG | 1 |
| Cai, Y; Kovacs, KJ; Larson, AA | 1 |
| Dunster, C; Grieve, DJ; Kelly, FJ; Li, JM; MacCarthy, PA; Shah, AM | 1 |
| Bozkurt, A; Hellström, PM; Schmidt, PT | 1 |
| Akerman, KE; De Loof, A; Detheux, M; Oonk, HB; Parmentier, M; Poels, J; Torfs, H; Van Loy, T; Vanden Broeck, J; Vassart, G | 1 |
| He, ZJ; Micci, MA; Pasricha, PJ; Shenoy, M; Toma, H; Winston, JH; Xiao, SY; Zou, L | 1 |
| Bunnett, NW; Divino, LA; Grady, EF; Grahn, SW; Hoge, SG; Kim, E; Kirkwood, KS; Wick, EC | 1 |
| Das, P; Dong, W; Ji, Y; Miksa, M; Ravikumar, TS; Wang, P; Wu, R; Yang, D; Zhang, F; Zhou, M | 1 |
| Ikeda, T; Matsushima, O; Naono, R; Nishimori, T; Sakoda, S; Sunakawa, N | 1 |
| Azimi, E; Graham, TA; Lerner, EA; Reddy, VB | 1 |
| Benter, T; Bräkling, S; Haack, A; Kersten, H; Langner, M; Polaczek, C; Thinius, M | 1 |
2 trial(s) available for arginine and substance p
| Article | Year |
|---|---|
Effect of NG-monomethyl-L-arginine on kinin-induced vasodilation in the human forearm.
Topics: Adult; Analysis of Variance; Arginine; Brachial Artery; Bradykinin; Drug Interactions; Endothelium, Vascular; Forearm; Humans; Infusions, Intra-Arterial; Male; Nitric Oxide; omega-N-Methylarginine; Plethysmography; Regional Blood Flow; Substance P; Vasodilation | 1994 |
Role of nitric oxide towards vasodilator effects of substance P and ATP in human forearm vessels.
Topics: Acetylcholine; Adenosine Triphosphate; Adolescent; Adult; Aged; Arginine; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Female; Forearm; Humans; Indomethacin; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Plethysmography; Regional Blood Flow; Substance P; Vasodilator Agents | 1997 |
136 other study(ies) available for arginine and substance p
| Article | Year |
|---|---|
Studies on peptides. LXXXI. Application of a new arginine derivative, NG-mesitylene-2-sulfonylarginine, to the synthesis of substance P and neurotensin.
Topics: Amino Acid Sequence; Animals; Arginine; Muscle Contraction; Muscle, Smooth; Neurotensin; Peptide Fragments; Rabbits; Substance P | 1979 |
N omega-nitro-L-arginine blocks the second phase but not the first phase of the endothelium-dependent relaxations induced by substance P in isolated rings of pig carotid artery.
Topics: Animals; Arginine; Carotid Arteries; Endothelium, Vascular; Female; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroarginine; Norepinephrine; Substance P; Swine; Vasoconstriction; Vasodilation | 1992 |
Endothelium-derived relaxing factor inhibits platelet adhesion to cultured porcine endocardial endothelium.
Topics: Animals; Arginine; Cells, Cultured; Endocardium; Endothelium; Hemoglobins; Humans; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Platelet Adhesiveness; Substance P; Superoxide Dismutase; Swine | 1992 |
Effect of nitro-L-arginine on endothelium-dependent hyperpolarizations and relaxations of pig coronary arteries.
Topics: Animals; Arginine; Bradykinin; Coronary Vessels; Dinoprost; Dose-Response Relationship, Drug; Endothelium; In Vitro Techniques; Indomethacin; Membrane Potentials; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Prostaglandin Antagonists; Substance P; Swine | 1992 |
Effects of trigeminal neurotransmitters on piglet pial arterioles.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arginine; Arterioles; Brain; Calcitonin Gene-Related Peptide; Dinoprostone; Indomethacin; Neurokinin A; Nitric Oxide; omega-N-Methylarginine; Pia Mater; Substance P; Swine; Trigeminal Nerve | 1992 |
Differences in the K(+)-channels opened by cromakalim, acetylcholine and substance P in rat aorta and porcine coronary artery.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Benzopyrans; Coronary Vessels; Cromakalim; Endothelium, Vascular; Glyburide; Male; omega-N-Methylarginine; Potassium; Potassium Channels; Pyrroles; Rats; Rats, Sprague-Dawley; Substance P; Swine | 1991 |
Different patterns of release of endothelium-derived relaxing factor and prostacyclin.
Topics: Acetylcholine; Adenosine Diphosphate; Animals; Arachidonic Acid; Arginine; Bradykinin; Cattle; Endothelium, Vascular; Epoprostenol; Hydrogen-Ion Concentration; In Vitro Techniques; Nitric Oxide; Rabbits; Radioimmunoassay; Substance P | 1992 |
Analysis of the importance of arginine 102 in neutral endopeptidase (enkephalinase) catalysis.
Topics: Amino Acid Sequence; Angiotensin I; Animals; Arginine; Base Sequence; Binding Sites; Blotting, Western; Catalysis; Endothelins; Enkephalins; Molecular Sequence Data; Mutagenesis, Site-Directed; Neprilysin; Rats; Substance P; Substrate Specificity | 1992 |
Effect of Ca2+ ionophores on membrane potential of pig coronary artery endothelial cells.
Topics: Animals; Arginine; Calcimycin; Cell Polarity; Coronary Vessels; Electrophysiology; Endothelium, Vascular; Ionomycin; Membrane Potentials; Muscle, Smooth, Vascular; Nitroarginine; Potassium Channels; Substance P; Swine; Tubocurarine; Vasodilation | 1992 |
Characterization of the receptor mediating relaxation to substance P in canine middle cerebral artery: no evidence for involvement of substance P in neurogenically mediated relaxation.
Topics: Animals; Arginine; Capsaicin; Cerebral Arteries; Dogs; Electric Stimulation; Endothelium, Vascular; In Vitro Techniques; omega-N-Methylarginine; Peptide Fragments; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P; Synaptic Transmission; Vasodilation | 1992 |
Thimerosal blocks stimulated but not basal release of endothelium-derived relaxing factor (EDRF) in dog isolated coronary artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arachidonic Acid; Arginine; Arteries; Bradykinin; Calcimycin; Coronary Vessels; Dogs; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Prostaglandin Endoperoxides, Synthetic; Substance P; Thimerosal; Vasoconstrictor Agents | 1992 |
Effects of nitric oxide synthase inhibitors, L-NG-nitroarginine and L-NG-nitroarginine methyl ester, on responses to vasodilators of the guinea-pig coronary vasculature.
Topics: Adenosine Triphosphate; Animals; Arginine; Bradykinin; Coronary Vessels; Female; Guinea Pigs; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitroarginine; Nitroprusside; Serotonin; Substance P; Vasodilation; Vasodilator Agents | 1992 |
Release of endothelium-derived relaxing factor from pig cultured aortic endothelial cells, as assessed by changes in endothelial cell cyclic GMP content, is inhibited by a phorbol ester.
Topics: Adenosine Triphosphate; Animals; Aorta, Thoracic; Arginine; Calcimycin; Catalase; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Hemoglobins; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Phorbol 12,13-Dibutyrate; Substance P; Superoxide Dismutase; Swine | 1990 |
Low basal and stimulated release of nitric oxide in atherosclerotic epicardial coronary arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adolescent; Adult; Arginine; Arteriosclerosis; Bradykinin; Child; Child, Preschool; Coronary Vessels; Dose-Response Relationship, Drug; Drug Synergism; Endothelium, Vascular; Humans; Middle Aged; Nitric Oxide; omega-N-Methylarginine; Prostaglandin Endoperoxides, Synthetic; Substance P; Vasoconstriction; Vasodilation | 1990 |
Mechanism underlying the response to vasodilator nerve stimulation in isolated dog and monkey cerebral arteries.
Topics: Animals; Arginine; Cerebral Arteries; Dogs; Electric Stimulation; Female; In Vitro Techniques; Macaca; Male; Nervous System Physiological Phenomena; Nicotine; Nitric Oxide; Nitroglycerin; omega-N-Methylarginine; Substance P; Vasodilation | 1990 |
Modulation of autonomic neuroeffector transmission by nitric oxide in guinea pig ileum.
Topics: Acetylcholine; Animals; Arginine; Choline; Electric Stimulation; Female; Guinea Pigs; Ileum; In Vitro Techniques; Isomerism; Kinetics; Male; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Nitric Oxide; omega-N-Methylarginine; Substance P; Synaptic Transmission | 1990 |
Acetylcholine-induced vasodilatation in rabbit hindlimb in vivo is not inhibited by analogues of L-arginine.
Topics: Acetylcholine; Animals; Arginine; Endothelium, Vascular; Female; Femoral Artery; Hindlimb; Male; Microspheres; Nitric Oxide; Nitroarginine; Nitroglycerin; omega-N-Methylarginine; Rabbits; Regional Blood Flow; Substance P; Vascular Resistance; Vasodilation | 1991 |
The role of nitric oxide in mediating endothelium dependent relaxations in the human epicardial coronary artery.
Topics: Adolescent; Adult; Arginine; Child; Child, Preschool; Coronary Vessels; Endothelium, Vascular; Humans; In Vitro Techniques; Indomethacin; Infant; Middle Aged; Nitric Oxide; omega-N-Methylarginine; Substance P | 1990 |
Evidence that endogenous nitric oxide modulates oedema formation induced by substance P.
Topics: Animals; Arginine; Edema; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Regional Blood Flow; Skin; Stereoisomerism; Substance P | 1990 |
Endothelial function of human gastroepiploic artery. Implications for its use as a bypass graft.
Topics: Arginine; Coronary Artery Bypass; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; In Vitro Techniques; Indomethacin; Nitroglycerin; omega-N-Methylarginine; Stomach; Substance P; Vascular Patency; Vasodilation | 1991 |
On-line measurement of nitric oxide release from organic nitrates in the intact coronary circulation.
Topics: Animals; Arginine; Bradykinin; Coronary Vessels; In Vitro Techniques; Molsidomine; Nitric Oxide; Nitroglycerin; omega-N-Methylarginine; Oxyhemoglobins; Rabbits; Substance P; Trypsin; Vasodilation | 1991 |
Relationship between sensory neuropeptides and other local vasoactive mediators in modulating gastric mucosal integrity.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arginine; Blood Pressure; Capsaicin; Gastric Mucosa; Male; Microcirculation; Muscle, Smooth, Vascular; Neurons, Afferent; Neuropeptides; omega-N-Methylarginine; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Inbred Strains; Substance P; Vasodilation | 1991 |
Application of photodiode array detection and fast atom bombardment mass spectrometry for the identification of the arginine residue in neuropeptides.
Topics: Amino Acid Sequence; Arginine; Chromatography, High Pressure Liquid; Dynorphins; Molecular Sequence Data; Phenylglyoxal; Spectrometry, Mass, Fast Atom Bombardment; Spectrophotometry, Ultraviolet; Substance P | 1991 |
Nerve-induced tachykinin-mediated vasodilation in skeletal muscle is dependent on nitric oxide formation.
Topics: Animals; Arginine; Atropine; Bradykinin; Calcitonin Gene-Related Peptide; Dinoprostone; Dose-Response Relationship, Drug; Electric Stimulation; Hindlimb; Hyperemia; Muscles; Neurokinin A; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pancuronium; Rabbits; Substance P; Tachykinins; Vasodilation | 1991 |
Sensory neuropeptides (substance P) and 4-11 SP enhance human neutrophils chemiluminescence; the role of L-arginine.
Topics: Arginine; Humans; Kinetics; Luminescent Measurements; Neutrophils; Peptide Fragments; Structure-Activity Relationship; Substance P; Tuftsin | 1986 |
High-performance liquid chromatographic determination of substance P-like arginine-containing peptide in rat brain by on-line post-column fluorescence derivatization with benzoin.
Topics: Animals; Arginine; Benzoin; Chromatography, High Pressure Liquid; Hypothalamus; Male; Peptides; Rats; Rats, Inbred Strains; Spectrometry, Fluorescence; Substance P | 1989 |
Modulation of the vasodepressor actions of acetylcholine, bradykinin, substance P and endothelin in the rat by a specific inhibitor of nitric oxide formation.
Topics: Acetylcholine; Animals; Arginine; Blood Pressure; Bradykinin; Endothelins; Epoprostenol; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitroglycerin; omega-N-Methylarginine; Peptides; Rats; Stereoisomerism; Substance P | 1989 |
Role of the N-terminal arginine in the histamine-releasing activity of substance P, bradykinin and related peptides.
Topics: Animals; Arginine; Histamine Release; In Vitro Techniques; Kinins; Mast Cells; Neuropeptides; Rats; Rats, Inbred Strains; Substance P | 1989 |
Isolation of a sialogogic peptide from bovine hypothalamic tissue and its characterization as substance P.
Topics: Amino Acids; Animals; Arginine; Chromatography, Gel; Chromatography, Ion Exchange; Duodenum; Electrophoresis; Guinea Pigs; Hydrogen-Ion Concentration; Hypothalamus; Ileum; Muscle Contraction; Muscle, Smooth; Peptides; Rats; Salivation; Substance P; Vasoconstrictor Agents | 1970 |
Synthesis of substance P analogs with arginine in position eleven.
Topics: Animals; Arginine; Chemical Phenomena; Chemistry; Guinea Pigs; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Structure-Activity Relationship; Substance P | 1984 |
Immunoreactive dog C-peptide level in the pancreatic vein.
Topics: Animals; Arginine; Blood Glucose; Blood Pressure; C-Peptide; Dogs; Glucose; Guinea Pigs; Insulin; Neurotensin; Pancreas; Peptides; Substance P; Veins | 1980 |
Nitric oxide mediates penile erection in cats.
Topics: Acetylcholine; Animals; Arginine; Cats; Cysteine; Dose-Response Relationship, Drug; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Penicillamine; Penile Erection; S-Nitroso-N-Acetylpenicillamine; S-Nitrosothiols; Substance P; Vasodilator Agents | 1994 |
Chronic EDRF inhibition and hypoxia: effects on pulmonary circulation and systemic blood pressure.
Topics: Animals; Arginine; Blood Pressure; Cardiac Output; Hemodynamics; Hypertension, Pulmonary; Hypoxia; In Vitro Techniques; Lung; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Organ Size; Perfusion; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Substance P; Vasodilation | 1993 |
Nitric oxide release from porcine mitral valves.
Topics: Adenosine Diphosphate; Amino Acid Oxidoreductases; Animals; Arginine; Biological Assay; Bradykinin; Calcimycin; Calcium; Culture Techniques; Endocardium; Endothelium; Epithelium; Mitral Valve; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Substance P; Swine; Thrombin | 1993 |
Overnight storage of the porcine isolated splenic artery enhances endothelium-dependent contractions to NG-nitro-L-arginine methyl ester without impairing endothelium-dependent dilator function.
Topics: Animals; Arginine; Endothelium, Vascular; Female; In Vitro Techniques; Kinetics; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Serotonin; Splenic Artery; Substance P; Swine; Time Factors; Vasodilation | 1994 |
The basal and stimulated release of the endothelium-derived relaxing factor from isolated pig coronary arteries does not interfere with the vascular release of superoxide.
Topics: Acridines; Animals; Arginine; Cattle; Coronary Vessels; Ditiocarb; In Vitro Techniques; Luminescent Measurements; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Substance P; Superoxide Dismutase; Superoxides; Swine | 1994 |
Increased endothelium-derived NO in hypertensive pulmonary circulation of chronically hypoxic rats.
Topics: Animals; Arginine; Chronic Disease; Hypertension; Hypoxia; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Substance P; Vasoconstriction | 1994 |
Distinct populations of sensory neurons mediate the peristaltic reflex elicited by muscle stretch and mucosal stimulation.
Topics: Animals; Arginine; Atropine; Capsaicin; Colon; Electric Stimulation; In Vitro Techniques; Intestinal Mucosa; Male; Muscle Contraction; Muscle Denervation; Muscle Relaxation; Muscle, Smooth; Neurons, Afferent; Nitroarginine; Peristalsis; Rats; Rats, Sprague-Dawley; Substance P; Time Factors; Vasoactive Intestinal Peptide | 1994 |
A vascular smooth muscles nitric oxide relaxation by a mechanism distinct of calcium changes.
Topics: Acetylcholine; Animals; Arginine; Bradykinin; Calcimycin; Calcium; Coronary Vessels; Cytosol; Dinoprost; Egtazic Acid; Endothelium, Vascular; Fura-2; In Vitro Techniques; Indomethacin; Ionomycin; Isometric Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Nitroglycerin; Potassium; Spectrometry, Fluorescence; Substance P; Swine | 1994 |
Impaired endothelium-dependent vasodilation in patients with essential hypertension: evidence that the abnormality is not at the muscarinic receptor level.
Topics: Acetylcholine; Arginine; Endothelium, Vascular; Female; Forearm; Humans; Hypertension; Male; Middle Aged; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Receptors, Muscarinic; Substance P; Vasodilation | 1994 |
Mechanism underlying substance P-induced relaxation in dog isolated superficial temporal arteries.
Topics: Analysis of Variance; Animals; Arginine; Cyclic AMP; Cyclic GMP; Dogs; Electrophysiology; Endothelium, Vascular; Female; In Vitro Techniques; Indomethacin; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroarginine; Substance P; Temporal Arteries | 1994 |
Effects of ageing on sensory nerve function in rat skin.
Topics: Afferent Pathways; Animals; Arginine; Blister; Capsaicin; Electric Stimulation; Female; Humans; Male; Neurons, Afferent; Nitroarginine; Nitroprusside; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Sciatic Nerve; Skin; Skin Aging; Substance P; Vasodilation | 1994 |
Comparative effects of N omega-nitro-L-arginine and N omega-nitro-L-arginine methyl ester on vasodilator responses to acetylcholine, bradykinin, and substance P.
Topics: Acetylcholine; Animals; Arginine; Bradykinin; Cats; Female; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroarginine; Splanchnic Circulation; Substance P; Vasodilator Agents | 1994 |
Comparative effects of L-NNA and alkyl esters of L-NNA on pulmonary vasodilator responses to ACh, BK, and SP.
Topics: Acetylcholine; Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Bradykinin; Cats; Female; Heart Rate; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; Pulmonary Circulation; Substance P; Vasodilation; Vasodilator Agents | 1994 |
Inhibition by calmodulin antagonists of the neurogenic relaxation in cerebral arteries.
Topics: Animals; Arginine; Calmodulin; Cerebral Arteries; Dogs; Electric Stimulation; Endothelium, Vascular; Female; Imidazoles; In Vitro Techniques; Isometric Contraction; Macaca; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nicotine; Nitric Oxide; Nitroarginine; Substance P; Sulfonamides | 1994 |
Inhibition of excitatory non-adrenergic non-cholinergic bronchoconstriction in guinea-pig airways in vitro by activation of an atypical 5-HT receptor.
Topics: Animals; Arginine; Bronchi; Bronchoconstriction; Charybdotoxin; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Male; Methiothepin; NG-Nitroarginine Methyl Ester; Phentolamine; Receptors, Serotonin; Scorpion Venoms; Substance P | 1994 |
Substance P induces biphasic endothelium-dependent relaxations in pig and rabbit carotid arteries.
Topics: Acetylcholine; Amino Acid Oxidoreductases; Animals; Arginine; Carotid Arteries; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Indomethacin; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroglycerin; Rabbits; Substance P; Swine; Vasodilation | 1994 |
Nitrovasodilator-induced relaxation and tolerance development in porcine vena cordis magna: dependence on intact endothelium.
Topics: Animals; Arginine; Cysteine; Dinoprost; Drug Tolerance; Endothelium, Vascular; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitrates; Nitroglycerin; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Substance P; Swine; Vasodilator Agents | 1994 |
Evidence for differential roles of nitric oxide (NO) and hyperpolarization in endothelium-dependent relaxation of pig isolated coronary artery.
Topics: Animals; Arginine; Coronary Vessels; Endothelium, Vascular; Female; In Vitro Techniques; Isometric Contraction; Male; Membrane Potentials; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Potassium; Substance P; Swine | 1994 |
Acetaminophen blocks spinal hyperalgesia induced by NMDA and substance P.
Topics: Acetaminophen; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arginine; Behavior, Animal; Dose-Response Relationship, Drug; Hyperalgesia; Injections, Spinal; N-Methylaspartate; Nociceptors; Rats; Rats, Sprague-Dawley; Spinal Cord Diseases; Substance P | 1994 |
Cutaneous vasodilatation induced by nitric oxide-evoked stimulation of afferent nerves in the rat.
Topics: Animals; Arginine; Calcitonin Gene-Related Peptide; Capsaicin; Female; Indoles; Isoindoles; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Peptide Fragments; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Skin; Substance P; Vasodilation | 1994 |
Nitric oxide mediates angiogenesis in vivo and endothelial cell growth and migration in vitro promoted by substance P.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Division; Cell Movement; Cells, Cultured; Cyclic GMP; DNA; Endothelium, Vascular; Neovascularization, Pathologic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Platelet Aggregation; Rabbits; Substance P | 1994 |
Intracellular messengers contributing to persistent nociception and hyperalgesia induced by L-glutamate and substance P in the rat formalin pain model.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arachidonic Acid; Arginine; Dexamethasone; Formaldehyde; Glutamic Acid; Hyperalgesia; Injections, Spinal; Isoquinolines; Male; Neurotransmitter Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nociceptors; Pain; Pain Measurement; Pain Threshold; Piperazines; Protein Kinase C; Rats; Reflex; Substance P | 1994 |
Substance P N-terminal metabolites and nitric oxide mediate capsaicin-induced antinociception in the adult mouse.
Topics: Analgesia; Animals; Arginine; Capsaicin; Dose-Response Relationship, Drug; Male; Methylene Blue; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peptide Fragments; Substance P | 1994 |
Involvement of substance P but not nitric oxide or calcitonin gene-related peptide in neurogenic plasma extravasation in rat incisor pulp and lip.
Topics: Animals; Arginine; Biphenyl Compounds; Calcitonin Gene-Related Peptide; Capillary Permeability; Dental Pulp; Electric Stimulation; Evans Blue; Gingiva; Incisor; Lip; Male; Mandibular Nerve; Neurons, Afferent; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peptide Fragments; Plasma; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Substance P | 1994 |
Role of nitric oxide in control of prolactin release by the adenohypophysis.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Atrial Natriuretic Factor; Cyclic GMP; Dibutyryl Cyclic GMP; Dopamine; Dose-Response Relationship, Drug; Guanylate Cyclase; Hemoglobins; In Vitro Techniques; Luteinizing Hormone; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Wistar; Substance P; Vasoactive Intestinal Peptide | 1995 |
Substance P: endothelial localization and pharmacology in the human ovarian vein.
Topics: Adult; Arginine; Carboprost; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Humans; Immunohistochemistry; In Vitro Techniques; Indomethacin; Middle Aged; NG-Nitroarginine Methyl Ester; Nitric Oxide; Ovary; Substance P; Vasodilation; Veins | 1995 |
Inhibition by SR 140333 of NK1 tachykinin receptor-evoked, nitric oxide-dependent vasodilatation in the hamster cheek pouch microvasculature in vivo.
Topics: Animals; Arginine; Arterioles; Cheek; Cricetinae; Male; Mesocricetus; Microcirculation; Mouth Mucosa; Neurokinin-1 Receptor Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Piperidines; Quinuclidines; Regional Blood Flow; Substance P; Tachykinins; Vasoconstriction; Vasodilation | 1994 |
Tachykinin NK3 receptor mediates NANC hyperpolarization and relaxation via nitric oxide release in the circular muscle of the guinea-pig colon.
Topics: Animals; Apamin; Arginine; Atropine; Colon; Dose-Response Relationship, Drug; Guanethidine; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth; Neurokinin B; Nitric Oxide; Nitroarginine; Oligopeptides; Peptide Fragments; Piperidines; Quinuclidines; Receptors, Neurokinin-3; Stereoisomerism; Substance P; Tetrodotoxin | 1994 |
Essential role for nitric oxide in neurogenic inflammation in rat cutaneous microcirculation. Evidence for an endothelium-independent mechanism.
Topics: Animals; Arginine; Blood Pressure; Cyclic GMP; Endothelium, Vascular; Indazoles; Inflammation; Male; Microcirculation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Regional Blood Flow; Skin; Substance P | 1995 |
Vascular bed-dependent roles of the peptide CGRP and nitric oxide in acid-evoked hyperaemia of the rat stomach.
Topics: Animals; Arginine; Arteries; Atropine; Blood Vessels; Calcitonin Gene-Related Peptide; Female; Gastric Mucosa; Hydrochloric Acid; Hyperemia; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peptide Fragments; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Stomach; Substance P | 1994 |
Nitric oxide-like activity in guinea pig colon as determined by effector responses, bioassay and chemiluminescence analysis.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Atropine; Biological Assay; Colon; Female; Guinea Pigs; Histamine Antagonists; Humans; In Vitro Techniques; Luminescent Measurements; Male; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Substance P; Synaptic Transmission | 1994 |
The differential mechanisms of mild irritants on adaptive cytoprotection.
Topics: Adaptation, Physiological; Animals; Arginine; Atropine; Capsaicin; Chorionic Gonadotropin; Ethanol; Gastric Mucosa; Hexamethonium; Indomethacin; Irritants; Lidocaine; Male; Mucus; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandins; Rats; Rats, Sprague-Dawley; Sodium Chloride; Stomach Ulcer; Substance P | 1994 |
Endogenous nitric oxide modulates behavioural effects elicited by substance P in rat.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Behavior, Animal; Eating; Male; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Substance P | 1994 |
Involvement of the kallikrein-kinin system in the salivary secretion elicited in rats by heat stress.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Arginine; Atropine; Bradykinin; Hot Temperature; Kallikrein-Kinin System; Kallikreins; Kininogens; Male; Nitroarginine; Pilocarpine; Rats; Rats, Inbred BN; Rats, Wistar; Saliva; Stress, Physiological; Submandibular Gland; Substance P | 1994 |
Myocardial performance is modulated by interaction of cardiac endothelium derived nitric oxide and prostaglandins.
Topics: Animals; Arachidonic Acid; Arginine; Cats; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Myocardial Contraction; Myocardium; Nitric Oxide; Nitroarginine; Papillary Muscles; Prostaglandins; Stimulation, Chemical; Substance P | 1995 |
Endogenous nitric oxide modulates acetylcholine-induced edema and vasoconstriction in isolated perfused rabbit lungs.
Topics: Acetylcholine; Animals; Arginine; Dose-Response Relationship, Drug; Female; Male; Nitric Oxide; Nitroarginine; Nitroprusside; Perfusion; Pulmonary Circulation; Pulmonary Edema; Rabbits; Substance P; Vasoconstriction | 1995 |
Calcitonin gene-related peptide mediated neurogenic vasorelaxation in the isolated canine lingual artery.
Topics: Animals; Arginine; Benzopyrans; Calcitonin Gene-Related Peptide; Capsaicin; Cromakalim; Dogs; Electric Stimulation; Female; Glyburide; Humans; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Peptide Fragments; Potassium Channel Blockers; Potassium Channels; Propranolol; Pyrroles; Substance P; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Vasoconstriction; Vasodilator Agents | 1995 |
Evidence that tachykinin NK1 and NK2 receptors mediate non-adrenergic non-cholinergic excitation and contraction in the circular muscle of guinea-pig duodenum.
Topics: Action Potentials; Adenosine Diphosphate; Animals; Apamin; Arginine; Atropine; Dose-Response Relationship, Drug; Duodenum; Electric Stimulation; Guanethidine; Guinea Pigs; Indomethacin; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin-1 Receptor Antagonists; Neuromuscular Junction; Nifedipine; Nitroarginine; Oligopeptides; Peptide Fragments; Peptides, Cyclic; Physalaemin; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P; Suramin; Thionucleotides | 1995 |
Calcitonin gene-related peptide, substance P and nitric oxide are involved in cutaneous inflammation following ultraviolet irradiation.
Topics: Animals; Arginine; Biphenyl Compounds; Calcitonin Gene-Related Peptide; Dermatitis; Edema; Hypnotics and Sedatives; Immunohistochemistry; Male; Miotics; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peptide Fragments; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Skin; Substance P; Ultrasonography; Ultraviolet Rays | 1995 |
Mechanism of bradykinin-induced plasma extravasation in the rat knee joint.
Topics: Adrenergic beta-Antagonists; Animals; Arginine; Blood Pressure; Bradykinin; Capillary Permeability; Enzyme Inhibitors; Indoles; Injections, Intra-Articular; Isoindoles; Knee Joint; Male; Mast Cells; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidopamine; Perfusion; Rats; Rats, Wistar; Regional Blood Flow; Serum Albumin; Substance P; Sympathectomy; Synovial Fluid | 1995 |
Mechanisms of endothelium-dependent responses to vasoactive agents in isolated porcine coronary arteries.
Topics: Acetylcholine; Animals; Arginine; Calcimycin; Cardiovascular Agents; Coronary Vessels; Endothelium, Vascular; Female; In Vitro Techniques; Isometric Contraction; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Norepinephrine; Oxyhemoglobins; Serotonin; Substance P; Swine | 1993 |
Selective inhibition of endothelium-dependent vasodilator capacity by Escherichia coli endotoxemia.
Topics: Acetylcholine; Adenosine Diphosphate; Animals; Arginine; Calcimycin; Endothelium, Vascular; Escherichia coli; Guinea Pigs; Lipopolysaccharides; Male; NG-Nitroarginine Methyl Ester; Shock, Septic; Substance P; Vasodilation | 1993 |
Modulation of airway epithelial cell ciliary beat frequency by nitric oxide.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Bradykinin; Bronchi; Cattle; Cilia; Epithelium; In Vitro Techniques; Isomerism; Isoproterenol; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Substance P | 1993 |
Mediators of nonadrenergic, noncholinergic inhibition in the proximal, middle and distal regions of rat colon.
Topics: Animals; Arginine; Chymotrypsin; Colon; Electric Stimulation; Gastrointestinal Motility; In Vitro Techniques; Male; Muscle, Smooth; Neurons; Nitric Oxide; Nitroarginine; Peptide Fragments; Rats; Rats, Wistar; Substance P; Vasoactive Intestinal Peptide | 1993 |
Functional difference between SP and NKA: relaxation of gastric muscle by SP is mediated by VIP and NO.
Topics: Animals; Arginine; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Neurokinin A; Nitric Oxide; Nitroarginine; Peptide Fragments; Stomach; Substance P; Tachykinins; Tetrodotoxin; Vasoactive Intestinal Peptide | 1993 |
L-NAME blocks responses to NMDA, substance P and noxious cutaneous stimuli in cat dorsal horn.
Topics: Animals; Appetite Depressants; Arginine; Cats; Electrodes; Electrophysiology; Extracellular Space; Iontophoresis; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Physical Stimulation; Quisqualic Acid; Skin; Skin Physiological Phenomena; Spinal Cord; Substance P | 1993 |
Failure of L-nitroarginine, a nitric oxide synthase inhibitor, to affect hypotension and plasma protein extravasation produced by tachykinin NK-1 receptor activation in rats.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Blood Proteins; Indoles; Injections, Intravenous; Isoindoles; Male; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Wistar; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P | 1993 |
Endothelium-dependent effects of substance P and calcitonin gene-related peptide on mouse pial arterioles.
Topics: Animals; Arginine; Arterioles; Calcitonin Gene-Related Peptide; Endothelium, Vascular; Evans Blue; Indomethacin; Lasers; Male; Mice; Mice, Inbred ICR; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Pia Mater; Substance P; Vasodilation | 1993 |
Regional differences in the vasodilator response to vasopressin in canine cerebral arteries in vivo.
Topics: Angiography; Animals; Arginine; Cerebral Arteries; Circle of Willis; Dogs; Dose-Response Relationship, Drug; Female; Male; Nitric Oxide; omega-N-Methylarginine; Regional Blood Flow; Substance P; Vasoactive Intestinal Peptide; Vasodilation; Vasopressins; Vertebral Artery | 1993 |
Effects of nitro-L-arginine on endothelium-dependent relaxation of canine cerebral arteries.
Topics: Animals; Arginine; Basilar Artery; Calcimycin; Cerebral Arteries; Dinoprost; Dogs; Endothelium, Vascular; Female; Femoral Artery; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Substance P | 1993 |
Regulation of distal esophageal mucosal blood flow: the roles of nitric oxide and substance P.
Topics: Animals; Arginine; Dogs; Esophagus; Hydrochloric Acid; Immunohistochemistry; Lidocaine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Regional Blood Flow; Substance P; Vagotomy | 1993 |
Nitric oxide-mediated retinal arteriolar and arterial dilatation induced by substance P.
Topics: Animals; Arginine; Arterioles; Dogs; Endothelium, Vascular; Female; Fluorescein Angiography; Image Processing, Computer-Assisted; Isometric Contraction; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Nitroglycerin; Photography; Retinal Artery; Substance P; Vasodilation | 1993 |
Serotonin-induced coronary spasm in a swine model. A minor role of defective endothelium-derived relaxing factor.
Topics: Animals; Arginine; Coronary Angiography; Coronary Vasospasm; Endothelium, Vascular; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Serotonin; Substance P; Swine; Swine, Miniature | 1993 |
Involvement of NK receptors and beta-adrenoceptors in nitric oxide-dependent relaxation of rabbit aorta rings following electrical-field stimulation.
Topics: Adrenergic beta-Antagonists; Animals; Aorta; Arginine; Benzalkonium Compounds; Electric Stimulation; In Vitro Techniques; Male; Morphine; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Phenylephrine; Rabbits; Receptors, Adrenergic, beta; Receptors, Tachykinin; Substance P; Vasodilation | 1993 |
Nitric oxide is the mediator of tachykinin NK3 receptor-induced relaxation in the circular muscle of the guinea-pig ileum.
Topics: Animals; Arginine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitroarginine; omega-Conotoxins; Peptide Fragments; Peptides; Receptors, Neurokinin-3; Substance P; Vasoactive Intestinal Peptide | 1993 |
Stretch revealed three components in the hyperpolarization of guinea-pig coronary artery in response to acetylcholine.
Topics: Acetylcholine; Animals; Arginine; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Epoprostenol; Female; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Mechanoreceptors; Membrane Potentials; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandins; Rabbits; Rats; Sheep; Substance P | 1993 |
Altered vascular permeability responses to substance P in diabetic rats: interactions with a nitric oxide synthesis inhibitor.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Glucose; Blood Pressure; Capillary Permeability; Diabetes Mellitus, Experimental; Dinoprostone; Drinking; Injections, Intravenous; Male; Nitric Oxide Synthase; Nitroarginine; Peptide Fragments; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Substance P | 1993 |
Modulation of neuroeffector transmission by endogenous nitric oxide: a role for acetylcholine receptor-activated nitric oxide formation, as indicated by measurements of nitric oxide/nitrite release.
Topics: Acetylcholine; Amino Acid Oxidoreductases; Animals; Arginine; Atropine; Electric Stimulation; Female; Guinea Pigs; Ileum; Iris; Luminescent Measurements; Male; Muscle Contraction; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Rabbits; Receptors, Cholinergic; Substance P; Synaptic Transmission | 1993 |
Differential effects of nitric oxide synthesis inhibition on basal blood flow and antidromic vasodilation in rat oral tissues.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Dental Pulp; Electric Stimulation; Hemodynamics; Laser-Doppler Flowmetry; Lip; Male; Mouth; Mouth Mucosa; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Submandibular Gland; Substance P; Vasodilation | 1993 |
Implication of a nitric oxide synthase mechanism in the action of substance P: L-NAME blocks thermal hyperalgesia induced by endogenous and exogenous substance P in the rat.
Topics: Animals; Arginine; Enzyme Inhibitors; Hyperalgesia; Injections, Spinal; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pain Measurement; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Neurokinin-1; Stereoisomerism; Substance P | 1995 |
Stable VIP analogue Ro-24-9981 potentiates substance P-induced plasma exudation in hamster cheek pouch.
Topics: Animals; Arginine; Calcimycin; Capsaicin; Cheek; Cricetinae; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Indomethacin; Ionophores; Male; Microcirculation; Mouth Mucosa; NG-Nitroarginine Methyl Ester; Peptides, Cyclic; Plasma; Substance P; Vasoactive Intestinal Peptide | 1995 |
Role of nitric oxide in tachykinin-induced increase in potential difference of rabbit tracheal mucosa.
Topics: Amiloride; Animals; Arginine; Electrophysiology; Epithelium; Histocytochemistry; Male; Membrane Potentials; Mucous Membrane; NADPH Dehydrogenase; Neurokinin A; Neurokinin B; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rabbits; Substance P; Tachykinins; Trachea | 1995 |
Effect of the neurotensin receptor antagonist SR48692 on rat blood pressure modulation by neurotensin.
Topics: Animals; Arginine; Blood Pressure; Dose-Response Relationship, Drug; Drug Administration Schedule; Enzyme Inhibitors; Histamine H1 Antagonists; Indomethacin; Injections, Intravenous; Kinetics; Male; Neurotensin; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pyrazoles; Pyrilamine; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Neurotensin; Substance P; Time Factors | 1996 |
Mechanism of endothelium-dependent relaxation induced by substance P in the coronary artery of the pig.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Analysis of Variance; Animals; Arginine; Biological Factors; Coronary Vessels; Endothelium, Vascular; Fluorometry; Fura-2; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitroarginine; Prostaglandin Endoperoxides, Synthetic; Substance P; Swine; Thromboxane A2; Vasoconstrictor Agents | 1995 |
Role of nitric oxide in the actions of substance P and other mediators of inflammation in rat skin microvasculature.
Topics: Adenosine Triphosphate; Animals; Arginine; Capillary Permeability; Female; Inflammation Mediators; Male; Neurokinin A; Nitric Oxide; Nitroarginine; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Serotonin; Skin; Substance P; Vasodilation | 1995 |
Precolumn fluorescence derivatization of the antagonist [Arg6,D-Trp7,9,MePhe8]-substance P[6-11] with benzoin in high-performance liquid chromatography and selective detection of arginine-containing fragments in its degradation products.
Topics: Amino Acid Sequence; Arginine; Benzoin; Chromatography, High Pressure Liquid; Fluorescent Dyes; Indicators and Reagents; Molecular Sequence Data; Peptide Fragments; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Substance P | 1996 |
Contrasting effects of blockade of nitric oxide formation on resistance and conductance coronary vessels in conscious dogs.
Topics: Acetylcholine; Adenosine; Animals; Arginine; Coronary Circulation; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Heart Rate; Neurotransmitter Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroglycerin; Regional Blood Flow; Substance P; Vasodilator Agents; Ventricular Pressure | 1996 |
Different modes of sensory neuropeptides and nitric oxide involvement in relaxation of guinea-pig vessels.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arginine; Calcitonin Gene-Related Peptide; Capsaicin; Dipeptides; Dose-Response Relationship, Drug; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Indoles; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Neurons, Afferent; Neuropeptides; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandin Endoperoxides, Synthetic; Receptors, Neurotransmitter; Substance P; Thromboxane A2; Vasoconstrictor Agents | 1995 |
Involvement of nitric oxide in the smooth muscle tone of the isolated canine spleen and the responses to acetylcholine and substance P.
Topics: Acetylcholine; Analysis of Variance; Animals; Arginine; Cardiovascular Agents; Cyclooxygenase Inhibitors; Dogs; Female; Indomethacin; Male; Methylene Blue; Muscle Tonus; Muscle, Smooth; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Organ Size; Spleen; Substance P; Vasodilation | 1996 |
Tachykinins stimulate nitric oxide generation by canine cultured tracheal epithelium.
Topics: Animals; Arginine; Cells, Cultured; Dogs; Epithelium; Glycopeptides; Neurokinin A; Neurokinin B; NG-Nitroarginine Methyl Ester; Nitric Oxide; Penicillamine; Receptors, Neurokinin-2; S-Nitroso-N-Acetylpenicillamine; Substance P; Trachea | 1995 |
Effect of SR 142801 on nitric oxide-dependent and independent responses to tachykinin NK3 receptor agonists in isolated guinea-pig colon.
Topics: Animals; Arginine; Colon; Electric Stimulation; Enzyme Inhibitors; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Peptide Fragments; Piperidines; Receptors, Neurokinin-3; Substance P | 1995 |
Role of endothelium in control of forearm blood flow in patients with heart failure.
Topics: Acetylcholine; Adult; Aged; Arginine; Endothelium, Vascular; Forearm; Heart Failure; Humans; Male; Middle Aged; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Substance P; Vascular Resistance; Vasodilator Agents; Vasomotor System | 1996 |
Nitric oxide mediates long-term hyperalgesic and antinociceptive effects of the N-terminus of substance P in the formalin assay in mice.
Topics: Analgesics; Animals; Arginine; Enzyme Inhibitors; Formaldehyde; Hyperalgesia; Injections, Intraperitoneal; Injections, Spinal; Male; Mice; Mice, Inbred Strains; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pain Measurement; Peptide Fragments; Stereoisomerism; Substance P; Time Factors | 1996 |
Role of endogenous nitric oxide in airway microvascular leakage induced by inflammatory mediators.
Topics: Aminoquinolines; Animals; Arginine; Asthma; Capillary Permeability; Coloring Agents; Dipeptides; Enzyme Inhibitors; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Guanylate Cyclase; Guinea Pigs; Histamine; Indoles; Inflammation Mediators; Injections, Intravenous; Leukotriene D4; Lung; Male; Microcirculation; Neurokinin-1 Receptor Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Organometallic Compounds; Substance P | 1997 |
Myocardial contractile effects of L-arginine in the human allograft.
Topics: Arginine; Cardiac Catheterization; Coronary Angiography; Endothelium, Vascular; Female; Heart Transplantation; Humans; Infusions, Intra-Arterial; Male; Middle Aged; Myocardial Contraction; Nitric Oxide; Nitric Oxide Synthase; Polymerase Chain Reaction; RNA, Messenger; Substance P; Ventricular Function, Left; Ventricular Pressure | 1997 |
Effect of chronic myocardial infarction on in vivo reactivity of skeletal muscle arterioles.
Topics: Acetylcholine; Animals; Arginine; Arterioles; Calcitonin Gene-Related Peptide; Chronic Disease; Hemodynamics; Male; Muscle, Skeletal; Myocardial Infarction; Nitroprusside; Rats; Rats, Sprague-Dawley; Substance P; Vasomotor System | 1997 |
L-arginine does not reverse impaired agonist-induced increases in macromolecular efflux during diabetes mellitus.
Topics: Animals; Arginine; Capillary Permeability; Cheek; Cricetinae; Dextrans; Diabetes Mellitus, Experimental; Extravasation of Diagnostic and Therapeutic Materials; Fluorescein-5-isothiocyanate; Histamine; Inflammation Mediators; Macromolecular Substances; Male; Mesocricetus; Substance P | 1997 |
L-arginine prevents cyclosporin A-induced pulmonary vascular dysfunction.
Topics: Acetylcholine; Animals; Arginine; Atrial Function, Left; Blood Pressure; Bradykinin; Cyclooxygenase Inhibitors; Cyclosporine; Dogs; Endothelium, Vascular; Indomethacin; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroglycerin; Peptidyl-Dipeptidase A; Pulmonary Artery; Pulmonary Circulation; Substance P; Vasodilation; Vasodilator Agents | 1997 |
Differential effects of L-N5-(1-iminoethyl)-ornithine on tone and endothelium-dependent vasodilator responses.
Topics: Acetylcholine; Adenosine; Adrenomedullin; Animals; Arginine; Blood Pressure; Bradykinin; Cats; Endothelium, Vascular; Female; Guanidines; Male; Muscle Tonus; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; Ornithine; Peptides; Pinacidil; Pulmonary Artery; Pulmonary Circulation; Substance P; Vasodilation; Vasodilator Agents | 1997 |
Nitric oxide contributes to substance P-induced increases in lung rapidly adapting receptor activity in guinea-pigs.
Topics: Adaptation, Physiological; Animals; Arginine; Blood Pressure; Enzyme Inhibitors; Guinea Pigs; Lung; Male; Microcirculation; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Respiratory Function Tests; Sensory Receptor Cells; Substance P; Substrate Specificity; Vagus Nerve | 1997 |
Substance P derivatives with photoactivatable labels in the N-terminal part of the molecule.
Topics: Amino Acid Sequence; Animals; Arginine; Benzoates; Brain Chemistry; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Iodine Radioisotopes; Isotope Labeling; Lysine; Mass Spectrometry; Peptide Fragments; Photoaffinity Labels; Rats; Receptors, Neurokinin-1; Receptors, Nicotinic; Structure-Activity Relationship; Substance P; Succinimides; Torpedo | 1997 |
Purification and characterization of an arginine-specific peptidase from ragweed (Ambrosia artemisiifolia) pollen.
Topics: Amino Acid Sequence; Arginine; Asthma; Endopeptidases; Hypersensitivity; Molecular Sequence Data; Neuropeptides; Pollen; Protease Inhibitors; Serine Endopeptidases; Substance P; Substrate Specificity; Vasoactive Intestinal Peptide | 1998 |
Contribution of nitric oxide and substance P to nonadrenergic, noncholinergic transmission in the guinea pig ileum.
Topics: Acetylcholine; Animals; Arginine; Electric Stimulation; Enzyme Inhibitors; Guinea Pigs; Ileum; Male; Muscle Contraction; Muscle, Smooth; Nitric Oxide; Nitroarginine; Substance P; Synaptic Transmission; Tetrodotoxin | 1998 |
Specificity of Pseudomonas aeruginosa serralysin revisited, using biologically active peptides as substrates.
Topics: Angiotensin I; Angiotensin II; Arginine; Bacterial Proteins; Endopeptidases; Fibrin Fibrinogen Degradation Products; Hydrolysis; Kinetics; Mass Spectrometry; Metalloendopeptidases; Oligopeptides; Peptide Fragments; Pseudomonas aeruginosa; Substance P; Substrate Specificity | 1998 |
Effects of changing the availability of the substrate for nitric oxide synthase by L-arginine administration on coronary vasomotor tone in angina patients with angiographically narrowed and in patients with normal coronary arteries.
Topics: Aged; Angina Pectoris; Arginine; Coronary Angiography; Coronary Artery Disease; Coronary Vessels; Endothelium, Vascular; Enzyme Inhibitors; Female; Humans; Male; Middle Aged; Nitric Oxide Synthase; Nitroglycerin; omega-N-Methylarginine; Substance P; Vasoconstriction | 1998 |
Effects of L- and D-arginine on the basal tone of human diseased coronary arteries and their responses to substance P.
Topics: Analysis of Variance; Arginine; Coronary Angiography; Coronary Disease; Coronary Vessels; Endothelium, Vascular; Female; Humans; Isomerism; Male; Middle Aged; Nitroglycerin; Substance P; Vasodilator Agents | 1999 |
L-arginine and substance P reverse the pulmonary endothelial dysfunction caused by congenital heart surgery.
Topics: Administration, Inhalation; Arginine; Cardiopulmonary Bypass; Endothelium, Vascular; Heart Defects, Congenital; Humans; Hypertension, Pulmonary; Infant; Infusions, Intravenous; Nitric Oxide; Oxygen; Postoperative Complications; Pulmonary Circulation; Substance P; Vascular Resistance; Vasodilation; Vasodilator Agents | 1999 |
The importance of C-terminal residues of vertebrate and invertebrate tachykinins for their contractile activities in gut tissues.
Topics: Amino Acid Substitution; Animals; Arginine; Cockroaches; Guinea Pigs; Helminth Proteins; Male; Methionine; Muscle Contraction; Neurokinin A; Neurokinin B; Neuropeptides; Species Specificity; Substance P | 1999 |
Effects of NO donors and synthase agonists on endothelial cell uptake of L-Arg and superoxide production.
Topics: Animals; Aorta; Arginine; Biological Transport; Bradykinin; Cattle; Cells, Cultured; Endothelium, Vascular; Enzyme Inhibitors; Hydrazines; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroarginine; Penicillamine; Substance P; Superoxides; Tritium | 2000 |
Qualitative and quantitative aspects of the degradation of several tripeptides derived from the antitumour peptide antagonist [Arg(6), D-Trp(7,9), MePhe(8)] substance P[6-11].
Topics: Antineoplastic Agents; Arginine; Chromatography, High Pressure Liquid; Diketopiperazines; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Mass Spectrometry; Peptide Fragments; Phenylalanine; Piperazines; Substance P | 1999 |
Nitric oxide deficiency contributes to impairment of airway relaxation in cystic fibrosis mice.
Topics: Animals; Arginine; Bronchoconstriction; Cystic Fibrosis; Dinoprostone; Disease Models, Animal; Electric Stimulation; Enzyme Inhibitors; Female; In Vitro Techniques; Male; Mice; Mice, Inbred CFTR; Muscle Relaxation; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Substance P; Trachea | 2001 |
Tetrahydrobiopterin: a critical cofactor for eNOS and a strategy in the treatment of endothelial dysfunction?
Topics: Animals; Arginine; Biopterins; Cardiovascular Diseases; Clinical Trials as Topic; Coronary Vessels; Dogs; Endothelium, Vascular; Enzyme Inhibitors; Histamine; Humans; Hypercholesterolemia; In Vitro Techniques; Infusions, Intra-Arterial; Ionophores; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Pteridines; Pterins; Reactive Oxygen Species; Species Specificity; Substance P; Swine; Vasoconstrictor Agents; Vasodilator Agents | 2001 |
Short-acting calcium antagonist clevidipine protects against reperfusion injury via local nitric oxide-related mechanisms in the jeopardised myocardium.
Topics: Analysis of Variance; Animals; Arginine; Calcium Channel Blockers; Endothelium, Vascular; Enzyme Inhibitors; Female; Male; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Pyridines; Random Allocation; Substance P; Swine; Vascular Resistance | 2001 |
Hypoxia impairs endothelium-dependent relaxation in organ cultured pulmonary artery.
Topics: Animals; Arginine; Biopterins; Caveolin 1; Caveolins; Cyclic GMP; Dinoprost; Dose-Response Relationship, Drug; Endothelium, Vascular; Hypoxia; Ionomycin; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroprusside; Organ Culture Techniques; Pulmonary Artery; Rabbits; RNA, Messenger; Substance P; Superoxide Dismutase; Vasoconstriction; Vasodilation; Vasodilator Agents | 2001 |
Substance P and its transglutaminase-synthesized spermine derivative elicit yawning behavior via nitric oxide in rats.
Topics: Animals; Arginine; Behavior, Animal; Catheterization; Dose-Response Relationship, Drug; Drug Interactions; Indoles; Injections, Intraperitoneal; Isoindoles; Male; N-Methylscopolamine; Neurokinin-1 Receptor Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Receptors, Neurokinin-1; Scopolamine; Stereoisomerism; Structure-Activity Relationship; Substance P; Substantia Nigra; Time Factors; Yawning | 2001 |
Neuronal nitric oxide synthase (nNOS) mRNA is down-regulated, and constitutive NOS enzymatic activity decreased, in thoracic dorsal root ganglia and spinal cord of the rat by a substance P N-terminal metabolite.
Topics: Animals; Arginine; Capsaicin; Ganglia, Spinal; Lumbar Vertebrae; Male; Nerve Degeneration; Nerve Fibers; Neurons, Afferent; Nitric Oxide; Nitric Oxide Synthase; Nociceptors; Pain; Peptide Fragments; Rats; Rats, Sprague-Dawley; RNA, Messenger; Spinal Cord; Substance P; Thoracic Vertebrae | 2001 |
Impaired endothelial regulation of ventricular relaxation in cardiac hypertrophy: role of reactive oxygen species and NADPH oxidase.
Topics: Animals; Antioxidants; Arginine; Ascorbic Acid; Biopterins; Deferoxamine; Drug Synergism; Endothelium, Vascular; Free Radical Scavengers; Glutathione; Guinea Pigs; Heart Ventricles; Hypertrophy, Left Ventricular; In Vitro Techniques; Male; Malondialdehyde; Metalloporphyrins; Myocardial Contraction; NADPH Oxidases; Oxidation-Reduction; Reactive Oxygen Species; Substance P | 2001 |
Tachykinin-stimulated small bowel myoelectric pattern: sensitization by NO inhibition, reversal by neurokinin receptor blockade.
Topics: Animals; Arginine; Dose-Response Relationship, Drug; Electromyography; Gastrointestinal Motility; Intestine, Small; Neurokinin A; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Receptors, Tachykinin; Substance P; Tachykinins | 2002 |
Analysis of C-terminally substituted tachykinin-like peptide agonists by means of aequorin-based luminescent assays for human and insect neurokinin receptors.
Topics: Aequorin; Amino Acid Substitution; Animals; Arginine; Cell Line; CHO Cells; Cricetinae; Humans; Insecta; Methionine; Peptide Fragments; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Species Specificity; Substance P; Tachykinins | 2002 |
Acute pancreatitis results in referred mechanical hypersensitivity and neuropeptide up-regulation that can be suppressed by the protein kinase inhibitor k252a.
Topics: Animals; Arginine; Calcitonin Gene-Related Peptide; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Ganglia, Spinal; Indole Alkaloids; Male; Neurons, Afferent; Nociceptors; Pain; Pain Threshold; Pancreatitis, Acute Necrotizing; Phosphorylation; Physical Stimulation; Protein Kinase C; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptor, trkA; RNA, Messenger; Spinal Cord; Substance P; Tachykinins; Up-Regulation | 2003 |
Transient receptor potential vanilloid 1, calcitonin gene-related peptide, and substance P mediate nociception in acute pancreatitis.
Topics: Animals; Arginine; Calcitonin Gene-Related Peptide; Capsaicin; Male; Neurons, Afferent; Pain; Pain Measurement; Pancreas; Pancreatitis; Rats; Rats, Sprague-Dawley; Receptors, Calcitonin Gene-Related Peptide; Spinal Cord; Spinal Nerves; Substance P; TRPV Cation Channels | 2006 |
Ghrelin inhibits sympathetic nervous activity in sepsis.
Topics: Animals; Arginine; Disease Models, Animal; Ghrelin; Injections, Intravenous; Injections, Intraventricular; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Ghrelin; Receptors, Neuropeptide Y; Sepsis; Signal Transduction; Substance P; Sympathetic Nervous System; Tumor Necrosis Factor-alpha | 2007 |
The amino-terminal region of hemokinin-1 regulates the induction of thermal hyperalgesia in rats.
Topics: Amino Acid Sequence; Animals; Arginine; Hyperalgesia; Male; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins; Serine; Substance P; Tachykinins; Threonine | 2010 |
A single amino acid in MRGPRX2 necessary for binding and activation by pruritogens.
Topics: Arginine; Glutamic Acid; HEK293 Cells; HeLa Cells; Humans; Models, Molecular; Nerve Tissue Proteins; p-Methoxy-N-methylphenethylamine; Pruritus; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Substance P | 2017 |
Charge Retention/Charge Depletion in ESI-MS: Experimental Evidence.
Topics: Arginine; Dimethyl Sulfoxide; Hydrogen Bonding; Lysine; Protons; Solvents; Spectrometry, Mass, Electrospray Ionization; Substance P; Thiophenes | 2020 |