arginine and sepiapterin

arginine has been researched along with sepiapterin in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (26.32)18.2507
2000's9 (47.37)29.6817
2010's4 (21.05)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Gross, SS; Levi, R1
Bult, H; Herman, AG; Jorens, PG; van Overveld, FJ; Vermeire, PA1
Gross, SS; Jaffe, EA; Kilbourn, RG; Levi, R1
Cañada, FJ; Lamas, S; Pérez-Sala, D; Saura, M1
Ishii, M; Momose, K; Shimizu, S; Yamamoto, T1
Huang, A; Keaney, JF; Venema, RC; Vita, JA1
Hatakeyama, K; Kelly, KA; Marinos, RS; Martinez-Zaguilan, R; Meininger, CJ; Rojas, JD; Wu, G1
Assreuy, J; Guimarães, C; Linden, R1
Tiefenbacher, CP1
Boucher, JL; Brunet, A; David-Dufilho, M; Devynck, MA; Millanvoye, E; Rendu, F; Topal, G1
Bryan, RM; Durante, W; Jiang, X; Liao, D; Randhawa, JK; Rumbaut, RE; Schafer, AI; Tan, H; Wang, H; Yang, F; Yang, X1
Behnke, BJ; Delp, MD; Muller-Delp, JM; Spier, SA; Wu, G1
Barlag, RE; Funovic, P; Jacob, RF; Korda, M; Kubant, R; Malinski, T; Mason, RP1
Kim, JW; Park, CH1
Cheng, H; Fan, X; Harris, RC; Paueksakon, P; Wang, H1
Bertagnolli, M; Cloutier, A; Comte, B; Germain, N; Huyard, F; Nuyt, AM; Yzydorczyk, C1
de Crom, R; Habib, SL; Janardhanan, P; Krishnan, M; Mohan, S; Natarajan, M; Reddick, RL; Roman, L; van Haperen, R1
Fernando, V; Furuta, S; Letson, J; Sharma, V; Walia, Y; Zheng, X1

Other Studies

19 other study(ies) available for arginine and sepiapterin

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Tetrahydrobiopterin synthesis. An absolute requirement for cytokine-induced nitric oxide generation by vascular smooth muscle.
    The Journal of biological chemistry, 1992, Dec-25, Volume: 267, Issue:36

    Topics: Amino Acid Oxidoreductases; Animals; Aorta; Arginine; Biopterins; Cells, Cultured; Cytosol; Hypoxanthines; Interferon-gamma; Kinetics; Lipopolysaccharides; Male; Methotrexate; Muscle, Smooth, Vascular; Myoglobin; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Oxidation-Reduction; Oxygen Consumption; Pteridines; Pterins; Rats; Rats, Inbred F344; Recombinant Proteins

1992
Pterins inhibit nitric oxide synthase activity in rat alveolar macrophages.
    British journal of pharmacology, 1992, Volume: 107, Issue:4

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Biopterins; Cells, Cultured; Citrulline; Hypoxanthines; Interferon-gamma; Macrophages, Alveolar; Male; Nitric Oxide Synthase; Nitrites; Pteridines; Pterins; Rats; Rats, Wistar; Recombinant Proteins

1992
Cytokine-activated endothelial cells express an isotype of nitric oxide synthase which is tetrahydrobiopterin-dependent, calmodulin-independent and inhibited by arginine analogs with a rank-order of potency characteristic of activated macrophages.
    Biochemical and biophysical research communications, 1991, Aug-15, Volume: 178, Issue:3

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Biopterins; Brain; Calmodulin; Cells, Cultured; Cycloheximide; Cytokines; Endothelium, Vascular; Interferon-gamma; Isoenzymes; Kinetics; Macrophage Activation; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase; Pteridines; Pterins; Recombinant Proteins; Tumor Necrosis Factor-alpha

1991
Role of tetrahydrobiopterin availability in the regulation of nitric-oxide synthase expression in human mesangial cells.
    The Journal of biological chemistry, 1996, Jun-14, Volume: 271, Issue:24

    Topics: Arginine; Biopterins; Cells, Cultured; Enzyme Induction; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Glomerular Mesangium; Humans; Interleukin-1; Kinetics; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitrites; Nitroprusside; Pteridines; Pterins; Recombinant Proteins; RNA, Messenger; Sugar Acids; Transcription, Genetic; Tumor Necrosis Factor-alpha

1996
Reduction by tetrahydrobiopterin of H2O2-induced endothelial cell injury.
    Pharmacology & toxicology, 1998, Volume: 82, Issue:6

    Topics: Animals; Arginine; Biopterins; Cattle; Cells, Cultured; Endothelium, Vascular; Hydrogen Peroxide; Ionomycin; omega-N-Methylarginine; Pteridines; Pterins; Rats; Serotonin

1998
Ascorbic acid enhances endothelial nitric-oxide synthase activity by increasing intracellular tetrahydrobiopterin.
    The Journal of biological chemistry, 2000, Jun-09, Volume: 275, Issue:23

    Topics: Animals; Aorta; Arginine; Ascorbic Acid; Atrial Natriuretic Factor; Biopterins; Calcimycin; Cattle; Cell Line; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Kinetics; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroprusside; Pteridines; Pterins; Recombinant Proteins; Spodoptera; Swine; Transfection

2000
Impaired nitric oxide production in coronary endothelial cells of the spontaneously diabetic BB rat is due to tetrahydrobiopterin deficiency.
    The Biochemical journal, 2000, Jul-01, Volume: 349, Issue:Pt 1

    Topics: Animals; Arginine; Biopterins; Calcium; Calmodulin; Chromatography, High Pressure Liquid; Diabetes Mellitus; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; GTP Cyclohydrolase; Immunoblotting; Kinetics; NADP; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Protein Isoforms; Pteridines; Pterins; Rats; Rats, Mutant Strains

2000
Paracrine neuroprotective effect of nitric oxide in the developing retina.
    Journal of neurochemistry, 2001, Volume: 76, Issue:4

    Topics: Animals; Animals, Newborn; Anisomycin; Arginine; Biopterins; Cell Death; Cells, Cultured; Cyclic GMP; Guanylate Cyclase; In Vitro Techniques; NADPH Dehydrogenase; Neuroprotective Agents; Nitric Oxide; Paracrine Communication; Penicillamine; Pteridines; Pterins; Rats; Rats, Inbred Strains; Retina; Retinal Ganglion Cells; S-Nitroso-N-Acetylpenicillamine

2001
Tetrahydrobiopterin: a critical cofactor for eNOS and a strategy in the treatment of endothelial dysfunction?
    American journal of physiology. Heart and circulatory physiology, 2001, Volume: 280, Issue:6

    Topics: Animals; Arginine; Biopterins; Cardiovascular Diseases; Clinical Trials as Topic; Coronary Vessels; Dogs; Endothelium, Vascular; Enzyme Inhibitors; Histamine; Humans; Hypercholesterolemia; In Vitro Techniques; Infusions, Intra-Arterial; Ionophores; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Pteridines; Pterins; Reactive Oxygen Species; Species Specificity; Substance P; Swine; Vasoconstrictor Agents; Vasodilator Agents

2001
Homocysteine induces oxidative stress by uncoupling of NO synthase activity through reduction of tetrahydrobiopterin.
    Free radical biology & medicine, 2004, Jun-15, Volume: 36, Issue:12

    Topics: Antioxidants; Arginine; Ascorbic Acid; Biopterins; Blotting, Western; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Ethidium; Fluorescent Dyes; Homocysteine; Humans; L-Lactate Dehydrogenase; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphorylation; Pterins; Reactive Nitrogen Species; Superoxides; Thrombin; Time Factors

2004
Hyperhomocystinemia impairs endothelial function and eNOS activity via PKC activation.
    Arteriosclerosis, thrombosis, and vascular biology, 2005, Volume: 25, Issue:12

    Topics: Animals; Antioxidants; Aorta, Thoracic; Arginine; Biopterins; Cells, Cultured; Cystathionine beta-Synthase; Endothelium, Vascular; Enzyme Activation; Female; Gene Expression Regulation, Enzymologic; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Homocysteine; Humans; Hyperhomocysteinemia; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Protein Kinase C; Pterins; Superoxide Dismutase; Vasodilation

2005
Ageing diminishes endothelium-dependent vasodilatation and tetrahydrobiopterin content in rat skeletal muscle arterioles.
    The Journal of physiology, 2008, Feb-15, Volume: 586, Issue:4

    Topics: Aging; Animals; Arginase; Arginine; Arterioles; Biopterins; Endothelium, Vascular; Enzyme Inhibitors; Male; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Pterins; Rats; Rats, Inbred F344; Vasodilation

2008
Effect of beta-blockers on endothelial function during biological aging: a nanotechnological approach.
    Journal of cardiovascular pharmacology, 2008, Volume: 51, Issue:2

    Topics: Adrenergic beta-Antagonists; Aging; Animals; Aorta, Thoracic; Arginine; Atenolol; Cellular Senescence; Endothelium, Vascular; In Vitro Techniques; Metoprolol; Nanotechnology; Nitric Oxide; Nitric Oxide Synthase Type III; Peroxynitrous Acid; Pterins; Rats; Rats, Inbred WKY; Superoxide Dismutase

2008
Effect of advanced glycation end products on oxidative stress and senescence of trabecular meshwork cells.
    Korean journal of ophthalmology : KJO, 2012, Volume: 26, Issue:2

    Topics: Acetylcysteine; Apoptosis; Arginine; Cell Survival; Cells, Cultured; Cellular Senescence; Glycation End Products, Advanced; Humans; Nitric Oxide; Oxidative Stress; Pterins; Reactive Oxygen Species; Serum Albumin, Bovine; Trabecular Meshwork

2012
Improvement of endothelial nitric oxide synthase activity retards the progression of diabetic nephropathy in db/db mice.
    Kidney international, 2012, Volume: 82, Issue:11

    Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Progression; Endothelium, Vascular; Glucose; Kidney Glomerulus; Mice; Nitric Oxide Synthase Type III; Pterins

2012
Developmental programming of eNOS uncoupling and enhanced vascular oxidative stress in adult rats after transient neonatal oxygen exposure.
    Journal of cardiovascular pharmacology, 2013, Volume: 61, Issue:1

    Topics: Age Factors; Animals; Animals, Newborn; Aorta; Arginine; Carbachol; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Hyperoxia; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Pterins; Rats; Rats, Sprague-Dawley; Superoxides; Vasodilation; Vasodilator Agents

2013
Enhancing eNOS activity with simultaneous inhibition of IKKβ restores vascular function in Ins2(Akita+/-) type-1 diabetic mice.
    Laboratory investigation; a journal of technical methods and pathology, 2015, Volume: 95, Issue:10

    Topics: Animals; Aorta; Arginine; Cattle; Cells, Cultured; Diabetes Mellitus, Type 1; Dietary Supplements; Endothelium, Vascular; Female; Heterozygote; Humans; Hypoglycemic Agents; Insulin; Male; Mice, Inbred C57BL; Mice, Transgenic; Nitric Oxide Synthase Type III; Phosphorylation; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Pterins; Recombinant Fusion Proteins; Salicylates; Weaning

2015
Correction of arginine metabolism with sepiapterin-the precursor of nitric oxide synthase cofactor BH
    Biochemical pharmacology, 2020, Volume: 176

    Topics: Arginine; B7-H1 Antigen; Biopterins; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Humans; Macrophages; Nitric Oxide; Nitric Oxide Synthase; Polyamines; Pterins; STAT3 Transcription Factor; THP-1 Cells

2020