arginine and sb 290157

arginine has been researched along with sb 290157 in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's13 (36.11)29.6817
2010's16 (44.44)24.3611
2020's7 (19.44)2.80

Authors

AuthorsStudies
Adams, JL; Ames, RS; Badger, AM; Bautsch, W; Bondinell, WE; Cousins, RD; Erhard, KF; Foley, JJ; Hieble, JP; Jurewicz, AJ; Klos, A; Lee, D; McCafferty, G; Osborn, RR; Sarau, HM; Settmacher, B; Sulpizio, AC; Tornetta, MA; Underwood, DC; Ward, KW1
Allendorf, DJ; Baran, JT; Janowska-Wieczorek, A; Kucia, M; Majka, M; Ratajczak, J; Ratajczak, MZ; Reca, R; Ross, GD; Wetsel, RA1
Arumugam, TV; Fairlie, DP; Proctor, LM; Reid, RC; Shiels, I; Taylor, SM1
Holland, MC; Lambris, JD; Morikis, D1
Therien, AG1
Bao, L; Haas, M; Osawe, I; Quigg, RJ1
Ducharme, Y; Friesen, RW; Gervais, FG; Greig, GM; Hamel, M; Kargman, S; Lau, CK; Mathieu, MC; O'Neill, GP; Sawyer, N; Therien, AG1
Fruehauf, S; Seeger, T; Topaly, J1
Mahadevan, IB; Proctor, LM; Shiels, IA; Strachan, AJ; Taylor, SM; Williams, HM; Woodruff, TM1
Connolly, ES; Ducruet, AF; Fusco, DJ; Hassid, BG; Hickman, ZL; Kim, GH; Komotar, RJ; Mack, WJ; Mocco, J; Otten, ML; Sosunov, SA1
Hatch, E; Lu, B; Sacks, SH; Sheerin, NS; Tang, Z1
Monk, PN; Moore, TA; Proctor, LM; Sanderson, SD; Taylor, SM; Woodruff, TM1
Connolly, ES; Garrett, MC; Komotar, RJ; Lambris, JD; Magotti, P; Otten, ML; Rynkowski, MA; Starke, RM1
Hutamekalin, P; Mizutani, N; Ogawa, N; Takeda, K; Tani, M; Tsuga, Y; Yoshino, S1
Goshima, H; Mizutani, N; Nabe, T; Yoshino, S1
Endo, M; Fukuda, N; Han, Y; Ikeda, K; Matsumoto, K; Matsumoto, T; Soma, M; Ueno, T; Xueli, Z1
Brown, L; Fairlie, DP; Iyer, A; Lim, J; Reid, RC; Seow, V; Suen, JY1
Endo, M; Fukuda, N; Ikeda, K; Kobayashi, N; Matsumoto, K; Soma, M; Ueno, T1
Atkinson, C; Kunchithapautham, K; Rohrer, B1
Li, SL; Shen, T; Wang, F; Wang, H; Wu, CH; Ye, LP; Zha, WS; Zhang, JX; Zhu, QX1
Fairlie, DP; Hamidon, JK; Lim, J; Reid, RC; Singh, R; Stoermer, MJ; Yau, MK1
Bellows-Peterson, ML; Branchett, W; Cooper, MA; Croker, DE; Floudas, CA; Halai, R; Kieslich, CA; Monk, PN; Morikis, D; Smadbeck, J; Woodruff, TM1
Chu, P; Durek, T; Fairlie, DP; Reed, AN; Reid, RC; Scully, CC; Singh, R; Suen, JY; Yau, MK1
Ahmad, S; Ducruet, AF; Larkin, TM; Lauver, MA; Zhao, XJ1
Bibikova, E; Danilova, N; Lin, S; Sakamoto, KM; Wilkes, M; Youn, MY1
Fernandez-Godino, R; Pierce, EA1
Ahmad, S; Bhatia, K; Ducruet, AF; Kindelin, A1
Anand, JP; Kumar, B; Panjwani, U; Prabhakar, A; Prasad, D; Ray, K; Wadhwa, M1
Banerjee, A; Bartley, M; Cohen, M; Coleman, JR; Moore, EE; Samuels, JM; Sauaia, A; Silliman, CC; Vigneshwar, N1
Catalin, B; Dumbrava, D; Gresita, A; Hermann, DM; Olaru, DG; Popa-Wagner, A; Surugiu, R1
Durek, T; Fairlie, DP; Halili, MA; Hamidon, JK; Iyer, A; Lim, J; Lohman, RJ; Poon, EKY; Reid, RC; Rowley, JA; Wu, KC; Yau, MK1
Gao, J; Guo, B; Hu, C; Long, H; Shu, C; Wang, X; Yang, F; Zha, H; Zhou, L; Zhu, B1
Ji, MH; Li, B; Li, SM; Sun, J; Yang, JJ; Zhang, GF; Zhang, L1
Lee, JD; Taylor, SM; Woodruff, TM1
Che, DJ; Tian, X; Wang, SS; Zheng, JM1
Hashimoto, M; Hikichi, T; Irie, H; Kato, T; Kobashi, R; Nakamura, J; Ohira, H; Okubo, Y; Sato, Y; Sugimoto, M; Suzuki, R; Takagi, T; Takasumi, M1

Reviews

3 review(s) available for arginine and sb 290157

ArticleYear
Synthetic small-molecule complement inhibitors.
    Current opinion in investigational drugs (London, England : 2000), 2004, Volume: 5, Issue:11

    Topics: Animals; Arginine; Benzhydryl Compounds; Humans; Membrane Proteins; Peptides, Cyclic; Receptor, Anaphylatoxin C5a; Receptors, Complement; Structure-Activity Relationship

2004
Innovative strategies for PBPC mobilization.
    Cytotherapy, 2005, Volume: 7, Issue:5

    Topics: Anti-HIV Agents; Arginine; Benzhydryl Compounds; Benzylamines; Cell Adhesion Molecules; Chemokine CXCL12; Chemokine CXCL2; Chemokines, CXC; Cyclams; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cells; Heterocyclic Compounds; Humans; Intercellular Signaling Peptides and Proteins; Ligands; Models, Immunological; Peripheral Blood Stem Cell Transplantation; Receptors, CXCR4; Transplantation, Autologous; Transplantation, Homologous

2005
The Role of Complement C3a Receptor in Stroke.
    Neuromolecular medicine, 2019, Volume: 21, Issue:4

    Topics: Animals; Arginine; Benzhydryl Compounds; Blood-Brain Barrier; Complement Activation; Complement C3a; Complement Inactivating Agents; Disease Models, Animal; Humans; Immunity, Innate; Mice; Mice, Knockout; Neuroimmunomodulation; Neuroprotective Agents; Receptors, Complement; Stroke; Translational Research, Biomedical

2019

Other Studies

33 other study(ies) available for arginine and sb 290157

ArticleYear
Identification of a selective nonpeptide antagonist of the anaphylatoxin C3a receptor that demonstrates antiinflammatory activity in animal models.
    Journal of immunology (Baltimore, Md. : 1950), 2001, May-15, Volume: 166, Issue:10

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Arthritis, Experimental; Benzhydryl Compounds; Binding, Competitive; Cell Line; Complement C3a; Complement Inactivator Proteins; Disease Models, Animal; Edema; Guinea Pigs; Hindlimb; Humans; Injections, Intraperitoneal; Leukocytosis; Male; Membrane Proteins; Mice; Muscle Contraction; Neutrophil Infiltration; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Receptors, Complement; Tumor Cells, Cultured

2001
Mobilization studies in mice deficient in either C3 or C3a receptor (C3aR) reveal a novel role for complement in retention of hematopoietic stem/progenitor cells in bone marrow.
    Blood, 2004, Mar-15, Volume: 103, Issue:6

    Topics: Animals; Arginine; Benzhydryl Compounds; Bone Marrow Cells; Bone Marrow Transplantation; Cell Movement; Complement Activation; Complement C3; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cells; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Mutant Strains; Radiation Chimera; Receptors, Complement

2004
Comparative anti-inflammatory activities of antagonists to C3a and C5a receptors in a rat model of intestinal ischaemia/reperfusion injury.
    British journal of pharmacology, 2004, Volume: 142, Issue:4

    Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Arginine; Australia; Benzhydryl Compounds; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Injections, Intravenous; Intestinal Mucosa; Membrane Proteins; Neutropenia; Neutrophils; Peptides, Cyclic; Rats; Rats, Wistar; Receptor, Anaphylatoxin C5a; Receptors, Complement; Reperfusion Injury; Time Factors

2004
Agonist activity of the small molecule C3aR ligand SB 290157.
    Journal of immunology (Baltimore, Md. : 1950), 2005, Jun-15, Volume: 174, Issue:12

    Topics: Animals; Arginine; Benzhydryl Compounds; Bronchial Hyperreactivity; Membrane Proteins; Mice; Receptors, Complement

2005
Signaling through up-regulated C3a receptor is key to the development of experimental lupus nephritis.
    Journal of immunology (Baltimore, Md. : 1950), 2005, Aug-01, Volume: 175, Issue:3

    Topics: Animals; Antibodies, Antinuclear; Apoptosis; Arginine; Benzhydryl Compounds; Complement C3a; Complement Inactivator Proteins; Fluorescent Antibody Technique, Indirect; Inflammation Mediators; Kidney; Lupus Erythematosus, Systemic; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Inbred MRL lpr; Phosphoric Monoester Hydrolases; Phosphorylation; PTEN Phosphohydrolase; Receptors, Complement; RNA, Messenger; Signal Transduction; Tumor Suppressor Proteins; Up-Regulation

2005
The C3a receptor antagonist SB 290157 has agonist activity.
    Immunology letters, 2005, Sep-15, Volume: 100, Issue:2

    Topics: Animals; Arginine; Benzhydryl Compounds; beta-Lactamases; Binding, Competitive; Blood Platelets; Calcium; Cell Line, Tumor; Cell Membrane; CHO Cells; Complement C3a; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Humans; Macaca fascicularis; Membrane Proteins; Rats; Receptors, Complement; Transfection; U937 Cells

2005
Complement inhibitors selectively attenuate injury following administration of cobra venom factor to rats.
    International immunopharmacology, 2006, Volume: 6, Issue:8

    Topics: Administration, Oral; Animals; Arginine; Benzhydryl Compounds; Blood Pressure; Bronchoalveolar Lavage Fluid; Cinnamates; Complement Inactivating Agents; Depsides; Elapid Venoms; Female; Injections, Intravenous; Leukocyte Count; Lung; Lung Diseases; Membrane Proteins; Molecular Structure; Neutrophils; Peptides, Cyclic; Rats; Rats, Wistar; Receptor, Anaphylatoxin C5a; Receptors, Complement; Rosmarinic Acid; Tumor Necrosis Factor-alpha

2006
C3a receptor modulation of granulocyte infiltration after murine focal cerebral ischemia is reperfusion dependent.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2008, Volume: 28, Issue:5

    Topics: Anaphylatoxins; Animals; Arginine; Benzhydryl Compounds; Brain; Brain Ischemia; Complement C3a; Disease Models, Animal; Flow Cytometry; Granulocytes; Infarction, Middle Cerebral Artery; Intercellular Adhesion Molecule-1; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Receptors, Complement; Reperfusion Injury

2008
C3a mediates epithelial-to-mesenchymal transition in proteinuric nephropathy.
    Journal of the American Society of Nephrology : JASN, 2009, Volume: 20, Issue:3

    Topics: Animals; Arginine; Benzhydryl Compounds; Cell Line; Collagen Type I; Complement Activation; Complement C3a; Complement Membrane Attack Complex; Epithelium; Female; Fibroblasts; Humans; Kidney Diseases; Kidney Tubules, Proximal; Macrophage-1 Antigen; Macrophages; Mesoderm; Mice; Mice, Inbred BALB C; Mice, Knockout; Proteinuria; Signal Transduction

2009
Complement factors C3a and C5a have distinct hemodynamic effects in the rat.
    International immunopharmacology, 2009, Volume: 9, Issue:6

    Topics: Animals; Arginine; Benzhydryl Compounds; Blood Pressure; Cell Degranulation; Cell Line; Complement C3a; Complement C5a; Female; Humans; Neutropenia; Neutrophils; Peptides; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Recombinant Proteins

2009
Synergistic neuroprotective effects of C3a and C5a receptor blockade following intracerebral hemorrhage.
    Brain research, 2009, Nov-17, Volume: 1298

    Topics: Analysis of Variance; Animals; Arginine; Behavior, Animal; Benzhydryl Compounds; Body Water; Brain; Brain Chemistry; Cerebral Hemorrhage; Cytoprotection; Drug Synergism; Exploratory Behavior; Flow Cytometry; Granulocytes; Male; Maze Learning; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Peptides, Cyclic; Random Allocation; Receptor, Anaphylatoxin C5a; Receptors, Complement; Spatial Behavior; Time Factors

2009
Effect of the C3a-receptor antagonist SB 290157 on anti-OVA polyclonal antibody-induced arthritis.
    Journal of pharmacological sciences, 2010, Volume: 112, Issue:1

    Topics: Animals; Antibodies; Arginine; Arthritis, Experimental; Benzhydryl Compounds; Complement C3a; Male; Mice; Mice, Inbred DBA; Ovum; Rats; Rats, Inbred Lew; Receptors, Complement

2010
Establishment and characterization of a murine model for allergic asthma using allergen-specific IgE monoclonal antibody to study pathological roles of IgE.
    Immunology letters, 2012, Jan-30, Volume: 141, Issue:2

    Topics: Allergens; Animals; Antigen-Antibody Complex; Arginine; Asthma; Benzhydryl Compounds; Bronchial Hyperreactivity; Cell Movement; Chronic Disease; Disease Models, Animal; Goblet Cells; Humans; Hyperplasia; Immunization; Immunoglobulin E; Immunoglobulin G; Mice; Mice, Inbred BALB C; Neutrophils; Ovalbumin; Receptors, Complement

2012
Role of complement 3a in the synthetic phenotype and angiotensin II-production in vascular smooth muscle cells from spontaneously hypertensive rats.
    American journal of hypertension, 2012, Volume: 25, Issue:3

    Topics: Angiotensin II; Animals; Arginine; Benzhydryl Compounds; Cells, Cultured; Complement C3a; Hypertension; Kruppel-Like Transcription Factors; Muscle, Smooth, Vascular; Phenotype; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Complement; RNA, Messenger

2012
C5aR and C3aR antagonists each inhibit diet-induced obesity, metabolic dysfunction, and adipocyte and macrophage signaling.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2013, Volume: 27, Issue:2

    Topics: 3T3-L1 Cells; Adipocytes; Animals; Arginine; Benzhydryl Compounds; Diet, High-Fat; Dietary Carbohydrates; Inflammation; Lipid Metabolism; Macrophages; Male; Metabolic Diseases; Mice; Obesity; Peptides, Cyclic; Rats; Rats, Wistar; Receptor, Anaphylatoxin C5a; Receptors, Complement; Signal Transduction

2013
Role of complement 3a in the growth of mesangial cells from stroke-prone spontaneously hypertensive rats.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2014, Volume: 36, Issue:1

    Topics: Actins; Angiotensin II; Animals; Arginine; Benzhydryl Compounds; Cell Proliferation; Complement C3a; Gene Expression; Hypertension; Kidney Cortex; Male; Mesangial Cells; Myocytes, Smooth Muscle; Osteopontin; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Complement; RNA, Messenger; Stroke

2014
Smoke exposure causes endoplasmic reticulum stress and lipid accumulation in retinal pigment epithelium through oxidative stress and complement activation.
    The Journal of biological chemistry, 2014, May-23, Volume: 289, Issue:21

    Topics: Acetylcysteine; Animals; Arginine; Benzhydryl Compounds; Blotting, Western; Cells, Cultured; Complement Activation; Complement Factor B; Complement Pathway, Alternative; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Free Radical Scavengers; Heat-Shock Proteins; Humans; Lipid Metabolism; Lipids; Macular Degeneration; Mice; Mice, Inbred C57BL; Mice, Knockout; Nicotiana; Nicotine; Oxidative Stress; Receptors, Complement; Retinal Pigment Epithelium; Reverse Transcriptase Polymerase Chain Reaction; Smoke; Transcription Factor CHOP

2014
Complement C3a binding to its receptor as a negative modulator of Th2 response in liver injury in trichloroethylene-sensitized mice.
    Toxicology letters, 2014, Aug-17, Volume: 229, Issue:1

    Topics: Animals; Arginine; Benzhydryl Compounds; Chemical and Drug Induced Liver Injury; Complement Activation; Complement C3a; Complement C5b; Female; Flow Cytometry; Fluorescent Antibody Technique; Immunohistochemistry; Interferon-gamma; Interleukin-4; Liver; Liver Function Tests; Mice; Mice, Inbred BALB C; Receptors, Complement; Skin; Solvents; Th2 Cells; Trichloroethylene

2014
Potent heterocyclic ligands for human complement c3a receptor.
    Journal of medicinal chemistry, 2014, Oct-23, Volume: 57, Issue:20

    Topics: Adjuvants, Immunologic; Arginine; Benzhydryl Compounds; Calcium; Cells, Cultured; Chemistry Techniques, Synthetic; Gene Expression Regulation; Heterocyclic Compounds; Humans; Hydrogen Bonding; Ligands; Macrophages; Receptors, Complement; Structure-Activity Relationship

2014
Derivation of ligands for the complement C3a receptor from the C-terminus of C5a.
    European journal of pharmacology, 2014, Dec-15, Volume: 745

    Topics: Animals; Arginine; Benzhydryl Compounds; Cell Degranulation; Cell Line; Complement C5a; Humans; Ligands; Macrophages; Peptide Fragments; Peptides, Cyclic; Protein Engineering; Rats; Receptor, Anaphylatoxin C5a; Receptors, Complement; Recombinant Proteins

2014
Potent complement C3a receptor agonists derived from oxazole amino acids: Structure-activity relationships.
    Bioorganic & medicinal chemistry letters, 2015, Dec-01, Volume: 25, Issue:23

    Topics: Amino Acids; Arginine; Benzhydryl Compounds; Dipeptides; Dose-Response Relationship, Drug; Humans; Ligands; Macrophages; Molecular Structure; Oxazoles; Receptors, Complement; Structure-Activity Relationship

2015
Tissue plasminogen activator mediates deleterious complement cascade activation in stroke.
    PloS one, 2017, Volume: 12, Issue:7

    Topics: Animals; Arginine; Benzhydryl Compounds; Brain; Brain Edema; Cell Death; Cells, Cultured; Complement C3; Endothelial Cells; Fibrinolysin; Hemoglobins; Hemorrhage; Humans; Immunohistochemistry; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Inbred C57BL; Stroke; Tissue Plasminogen Activator

2017
Innate immune system activation in zebrafish and cellular models of Diamond Blackfan Anemia.
    Scientific reports, 2018, 03-26, Volume: 8, Issue:1

    Topics: Activin Receptors; Activins; Anemia, Diamond-Blackfan; Animals; Arginine; Benzamides; Benzhydryl Compounds; Complement C3a; Dioxoles; Disease Models, Animal; Humans; Immunity, Innate; Interferons; K562 Cells; Receptor, Transforming Growth Factor-beta Type I; Ribosomal Proteins; RNA, Small Interfering; Toll-Like Receptor 3; Transforming Growth Factor beta; Tumor Suppressor Protein p53; Up-Regulation; Zebrafish; Zebrafish Proteins

2018
C3a triggers formation of sub-retinal pigment epithelium deposits via the ubiquitin proteasome pathway.
    Scientific reports, 2018, 06-26, Volume: 8, Issue:1

    Topics: Anaphylatoxins; Arginine; Benzhydryl Compounds; Cells, Cultured; Complement Activation; Complement C3a; Cysteine Proteinase Inhibitors; Enzyme-Linked Immunosorbent Assay; Extracellular Matrix; Humans; Leupeptins; Macular Degeneration; Matrix Metalloproteinase 2; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Retinal Pigment Epithelium

2018
Complement activation sustains neuroinflammation and deteriorates adult neurogenesis and spatial memory impairment in rat hippocampus following sleep deprivation.
    Brain, behavior, and immunity, 2019, Volume: 82

    Topics: Animals; Arginine; Benzhydryl Compounds; Cognitive Dysfunction; Complement Activation; Complement C3a; Hippocampus; Male; Neurogenesis; Neuroimmunomodulation; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Complement; Signal Transduction; Sleep Deprivation; Spatial Memory; Temporal Lobe

2019
Alternative Complement Pathway Activation Provokes a Hypercoagulable State with Diminished Fibrinolysis.
    Shock (Augusta, Ga.), 2020, Volume: 53, Issue:5

    Topics: Adult; Aniline Compounds; Arginine; Benzhydryl Compounds; Blood Coagulation Disorders; Complement Activation; Complement Inactivating Agents; Complement Pathway, Alternative; Elapid Venoms; Female; Fibrinolysis; Humans; Male; Middle Aged; Peptides, Cyclic; Tetrahydronaphthalenes; Thrombelastography; Young Adult

2020
Intracortical Administration of the Complement C3 Receptor Antagonist Trifluoroacetate Modulates Microglia Reaction after Brain Injury.
    Neural plasticity, 2019, Volume: 2019

    Topics: Animals; Arginine; Benzhydryl Compounds; Disease Models, Animal; Mice; Microglia; Neurons; Phagocytosis; Receptors, Complement; Recovery of Function; Stroke; Trifluoroacetic Acid

2019
Potent Thiophene Antagonists of Human Complement C3a Receptor with Anti-Inflammatory Activity.
    Journal of medicinal chemistry, 2020, 01-23, Volume: 63, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Benzhydryl Compounds; Calcium; Complement C3a; Hexosaminidases; Humans; Macrophages; Mast Cells; Microsomes, Liver; Rats; Rats, Wistar; Receptors, Complement; Small Molecule Libraries; Structure-Activity Relationship; Thiophenes

2020
C3a-C3aR signaling promotes breast cancer lung metastasis via modulating carcinoma associated fibroblasts.
    Journal of experimental & clinical cancer research : CR, 2020, Jan-13, Volume: 39, Issue:1

    Topics: Animals; Arginine; Benzhydryl Compounds; Breast Neoplasms; Cancer-Associated Fibroblasts; Cell Line, Tumor; Complement C3; Cytokines; Extracellular Matrix Proteins; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mice; Neoplasm Invasiveness; Neoplasm Transplantation; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Receptors, Complement; Signal Transduction

2020
A complement-microglial axis driving inhibitory synapse related protein loss might contribute to systemic inflammation-induced cognitive impairment.
    International immunopharmacology, 2020, Volume: 87

    Topics: Animals; Arginine; Astrocytes; Benzhydryl Compounds; Cognitive Dysfunction; Complement C3; Electrical Synapses; Hippocampus; Humans; Male; Mice; Mice, Inbred C57BL; Microglia; Neurogenic Inflammation; Receptors, Complement; Signal Transduction

2020
Is the C3a receptor antagonist SB290157 a useful pharmacological tool?
    British journal of pharmacology, 2020, Volume: 177, Issue:24

    Topics: Animals; Arginine; Benzhydryl Compounds; Mice; Stroke; Thrombolytic Therapy

2020
Sustained activation of C3aR in a human podocyte line impairs the morphological maturation of the cells.
    Molecular medicine reports, 2020, Volume: 22, Issue:6

    Topics: Arginine; Benzhydryl Compounds; Cell Line; Complement Activation; Complement C3a; Humans; Podocytes; Receptors, Complement

2020
The Complement C3a-C3a Receptor Axis Regulates Epithelial-to-Mesenchymal Transition by Activating the ERK Pathway in Pancreatic Ductal Adenocarcinoma.
    Anticancer research, 2022, Volume: 42, Issue:3

    Topics: Aged; Aged, 80 and over; Arginine; Benzhydryl Compounds; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Movement; Cell Proliferation; Complement C3; Complement Inactivating Agents; Enzyme Activation; Epithelial-Mesenchymal Transition; Extracellular Signal-Regulated MAP Kinases; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Middle Aged; Neoplasm Invasiveness; Pancreatic Neoplasms; Receptors, Complement; Signal Transduction

2022