arginine and pyruvaldehyde

arginine has been researched along with pyruvaldehyde in 108 studies

Research

Studies (108)

TimeframeStudies, this research(%)All Research%
pre-19909 (8.33)18.7374
1990's17 (15.74)18.2507
2000's28 (25.93)29.6817
2010's36 (33.33)24.3611
2020's18 (16.67)2.80

Authors

AuthorsStudies
Takahashi, K1
Davidson, WS; Flynn, TG1
Patthy, L1
Egyud, LG; Lipinski, B1
Battiston, L; Passamonti, S; Sottocasa, GL1
Colanduoni, JA; Villafranca, JJ1
Berrocal, F; Carreras, J1
El Kebbaj, MS; Gaudemer, Y; Latruffe, N; Moussard, C1
Bonsignore, A; Leoncini, G; Maresca, M; Ronchi, S1
Chang, GG; Huang, TM1
Chang, GG; Chang, TC; Chueh, SH; Pan, F1
Lo, TW; McLellan, AC; Selwood, T; Thornalley, PJ; Westwood, ME1
Selwood, T; Thornalley, PJ1
Kendrick, KE; White, PJ1
Thornalley, PJ; Westwood, ME1
Abordo, EA; Argirov, OK; Thornalley, PJ; Westwood, ME1
Bando, I; Furuta, T; Koshino, H; Moriya, N; Tajika, T; Uramoto, M1
Khor, OT; Miyata, T; Osawa, T; Oya, T; Uchida, K; Yasuda, Y1
Glomb, MA; Nagaraj, RH; Shipanova, IN1
Abordo, EA; Thornalley, PJ1
Ferry, JG; Rasche, ME; Smith, KS1
Aoyama, I; Hirasawa, Y; Miyazaki, S; Miyazaki, T; Morita, T; Niwa, T; Shimokata, K; Takayama, F; Tsukushi, S1
Baynes, JW; Degenhardt, TP; Thorpe, SR1
Maeda, K; Matsumoto, Y; Odani, H; Shinzato, T; Usami, J1
Hattori, N; Maeda, S; Miyata, S; Mizuno, Y; Osawa, T; Oya, T; Uchida, K1
Klaiber, RG; Lederer, MO1
Gombás, J; Kolev, K; Léránt, I; Machovich, R1
Asahi, K; Inagi, R; Izuhara, Y; Kurokawa, K; Miyata, T; Saito, A; Ueda, Y; VAN Ypersele DE Strihou, C1
Goffin, E; Inagi, R; Ishibashi, Y; Izuhara, Y; Kurokawa, K; Miyata, T; Saito, A; Ueda, Y; Van Ypersele De Strihou, C; Yoshino, A1
Arnold, BM; Chellan, P; Nagaraj, RH; Wilker, SC1
Belágyi, J; Kovács, T; Mazák, I; Nagy, J; Pótó, L; Vas, T; Wagner, L; Wagner, Z; Wittmann, I1
Bank, RA; Baynes, JW; Ben, ZC; Bijlsma, JW; Brau-Benjamin, O; DeGroot, J; Lafeber, FP; Maroudas, A; Mizrahi, J; Schalkwijk, CG; TeKoppele, JM; Thorpe, SR; Verzijl, N1
Biemel, KM; Lederer, MO; Mally, A; Nagaraj, RH; Padayatti, PS; Sarkar, P1
Chang, RC; Chiou, JF; Liu, TZ; Tsai, CH1
Dohmae, N; Honke, K; Koh, YH; Miyamoto, Y; Park, YS; Suzuki, K; Takahashi, M; Takio, K; Taniguchi, N1
Crabb, JW; Kumar, R; Levison, B; Mehta, S; Nagaraj, RH; Oya-Ito, T; Padayatti, PS; Padival, AK; Sun, J; West, K1
Ahmed, N; Dawczynski, J; Franke, S; Haik, GM; Stein, G; Strobel, J; Thornalley, PJ1
Lapolla, A; Ragazzi, E; Reitano, R; Sartore, G; Seraglia, R; Traldi, P1
Ahmed, N; Thornalley, PJ1
Chetyrkin, SV; Chuang, P; Ham, AJ; Hudson, BG; Mathieson, PW; Pedchenko, VK; Saleem, MA; Voziyan, PA1
Bhat, M; Biswas, A; Miller, A; Nagaraj, RH; Oya-Ito, T; Santhoshkumar, P1
Gratzer, PF; Lee, JM; Santerre, JP1
Nagaraj, RH; Padival, S1
Ames, JM; Baynes, JW; Brock, JW; Cotham, WE; Thorpe, SR1
Gao, Y; Wang, Y1
Arora, PD; Chong, SA; Laschinger, C; Lee, W; Manolson, M; McCulloch, CA; Simmons, CA; Sodek, J; Young, EW1
Biswas, A; Nagaraj, RH; Puttaiah, S; Staniszewska, M1
Auge, N; Ayala, V; Cantero, AV; Elbaz, M; Nègre-Salvayre, A; Pamplona, R; Portero-Otín, M; Salvayre, R; Sanson, M; Thiers, JC1
Brownlee, M; Edelstein, D; Giardino, I; Hammes, HP; Matsumura, T; Pestell, R; Rabbani, N; Sarthy, VP; Suske, G; Taguchi, T; Thornalley, PJ; Yao, D1
Barto, R; Brouwers, O; Schalkwijk, CG; Stehouwer, CD; Teerlink, T; van Bezu, J1
Barter, PJ; Brown, BE; Davies, MJ; Nobécourt, E; Rye, KA; Yadav, S; Zeng, J1
Blatt, T; Grune, T; Kueper, T; Lenz, H; Muhr, GM; Stäb, F; Wenck, H; Wittern, KP1
Azuma, M; Hirata, T; Kiyama, H; Konishi, H; Nakadate, Y; Shikata, K; Tachibana, T; Uchida, K; Yoshimura, S1
Chaudhuri, BS; Ray, M; Ray, S; Talukdar, D1
Glomb, MA; Klöpfer, A; Spanneberg, R1
Chetyrkin, S; Hachey, DL; Hudson, B; Madu, H; Mathis, M; McDonald, WH; Pedchenko, V; Sanchez, OA; Stec, D; Voziyan, P1
Chen, F; Ma, J; Peng, X; Wang, M; Zhang, X1
Biswas, A; Nagaraj, RH; Panda, AK; Pasupuleti, N; Santhoshkumar, P; Shanthakumar, S; Wang, B1
Field, MJ; Moosavi-Movahedi, AA; Nasiri, R; Zahedi, M1
Desai, K; Dhar, A; Dhar, I; Wu, L1
Kartika, R; Spiegel, DA; Wang, T1
Abetew, D; Christianson, C; Enquobahrie, DA; Hevner, K; Qiu, CF; Sheaff, C; Williams, MA; Zimmer, J1
Cohenford, M; Dain, JA; Frost, LR; Pampati, PK; Suravajjala, S1
Davies, MJ; Morgan, PE; Pattison, DI; Sheahan, PJ1
Brenner, T; Bruckner, T; Fleming, TH; Hofer, S; Martin, EO; Schemmer, P; Spranz, D; Uhle, F; Weigand, MA1
Chumsae, C; Gifford, K; Lian, W; Liu, H; Radziejewski, CH; Zhou, ZS1
Barzilay, JI; Fonseca, V; Goldfine, AB; Jablonski, KA; Monnier, VM; Shoelson, SE; Strauch, C1
Davies, MJ; Morgan, PE; Sheahan, PJ1
Aldini, G; Altomare, A; Bertoletti, L; Carini, M; Colombo, R; Colzani, M; De Lorenzi, E; Marchese, L; Regazzoni, L; Vistoli, G1
Miller, CB; Szwergold, BS1
Battocchio, C; Cipolla, L; Nicotra, F; Polzonetti, G; Russo, L; Taraballi, F1
Bellahcène, A; Belpomme, D; Bianchi, E; Castronovo, V; Chiavarina, B; Delvenne, P; Durieux, F; Irigaray, P; Nokin, MJ; Peixoto, P; Peulen, O; Turtoi, A; Uchida, K1
Bui, LC; Dairou, J; Lamouri, A; Leger, T; Mihoub, M; Richarme, G1
Augner, K; Eichler, J; Pischetsrieder, M; Utz, W1
Abdallah, J; Dairou, J; Gontero, B; Mihoub, M; Richarme, G1
Cleary, PA; Gao, X; Genuth, S; Lachin, JM; Monnier, VM; Sell, DR; Sun, W1
Kimzey, MJ; Kinsky, OR; Lau, SS; Monks, TJ; Stump, CS; Tsaprailis, G; Yassine, HN1
Scheckhuber, CQ1
Morales, FJ; Navarro, M1
Yaylayan, VA; Zhu, Y1
Opekar, F; Tůma, P1
Alizadeh, M; Kheirouri, S1
Afsar, M; Al-Bagmi, MS; Bano, B; Bhat, SA; Bhat, WF; Khan, MS1
Beavers, WN; Galligan, JJ; Kingsley, PJ; Marnett, LJ; Mitchener, MM; Rose, KL; Spiegel, DA; Streeter, MD; Wang, T; Wauchope, OR; Wepy, JA1
Ahmad, I; Bollong, MJ; Chang, JW; Chatterjee, AK; Chin, EN; Coukos, JS; Lairson, LL; Lee, G; Moellering, RE; Schultz, PG; Yun, H; Zambaldo, C1
Blair, CA; Campbell, KS; Holewinski, RJ; Kirk, JA; Li, A; Martin, TG; Moravec, CS; Papadaki, M; Previs, SB; Stachowski, MJ; Van Eyk, JE; Warshaw, DM1
Alsugoor, MH; Benham, CD; Lione, LA; Shamsaldeen, YA1
Nakaya, I; Nakayama, K; Nakayama, M; Soma, J; Tezuka, Y; Yahata, M1
Bekki, M; Fukumoto, Y; Honda, A; Igata, S; Kojima, R; Maeda, S; Matsui, T; Nakamura, T; Sugiyama, Y; Sun, J; Tahara, A; Tahara, N; Yamagishi, SI; Yoshida, R1
Degen, J; Henle, T; Löbner, J; Spengler, F; Treibmann, S1
Ahmad, S; Alatar, AA; Faisal, M; Rehman, S1
David, Y; Osunsade, A; Zheng, Q1
Bast, A; Opperhuizen, A; van der Lugt, T; van Leeuwen, S; Venema, K; Vrolijk, MF1
Alizadeh, M; Esmaeili, F; Kheirouri, S; Maleki, V1
Choi, S; Fica-Contreras, SM; Hedges, JS; Henning, NJ; Shuster, SO1
Glomb, MA; Nagaraj, RH; Nandi, SK; Rankenberg, J1
Akhter, A; Akhter, F; Chen, D; Yan, SF; Yan, SS1
El Qaidi, S; Hardwidge, PR; Scott, NE1
Dave, J; Fraser, S; Guir, ALS; McEwen, JM; Scheck, RA1
Inoue, Y; Iwai, M; Kadoyama, K; Matsumoto, K; Nitta, Y; Takano-Ohmuro, H; Takasugi, R; Takenokuchi, M; Taniguchi, T; Yoshida, K1
Ibarra, I; Martinez-Peon, D; Que-Salinas, U; Reyes-Figueroa, AD; Scheckhuber, CQ1
Groß, J; Henle, T; Pätzold, S; Treibmann, S1
Cunha, MP; Dafre, AL; de Almeida, GRL; Selhorst, I; Szczepanik, JC1
Davies, MJ; Fuentes-Lemus, E; López-Alarcón, C; Reyes, JS1
Deng, Y; Huang, L; Wang, X; Xie, P; Zhang, C; Zhang, Y1
Alzayadneh, EM; Caldwell, RB; Caldwell, RW; Shatanawi, A1
Ho, CT; Huang, SF; Hung, WL; Liao, KW; Lin, YY1
Addipilli, R; Kannoujia, J; Lingampelly, SS; Rodda, R; Sripadi, P1

Reviews

2 review(s) available for arginine and pyruvaldehyde

ArticleYear
Curcumin against advanced glycation end products (AGEs) and AGEs-induced detrimental agents.
    Critical reviews in food science and nutrition, 2019, Volume: 59, Issue:7

    Topics: Animals; Antioxidants; Apoptosis; Arginine; Cell Death; Cell Proliferation; Curcumin; Databases, Factual; DNA Damage; Glycation End Products, Advanced; Humans; Lysine; NF-kappa B; Oxidative Stress; Pyruvaldehyde; Receptor for Advanced Glycation End Products

2019
The expanding impact of methylglyoxal on behavior-related disorders.
    Progress in neuro-psychopharmacology & biological psychiatry, 2023, 01-10, Volume: 120

    Topics: Arginine; Cysteine; Dopamine; Glycation End Products, Advanced; Humans; Lysine; Magnesium Oxide; Mental Disorders; Nucleotides; Pain; Pyruvaldehyde

2023

Trials

5 trial(s) available for arginine and pyruvaldehyde

ArticleYear
Effect of dwell time on carbonyl stress using icodextrin and amino acid peritoneal dialysis fluids.
    Kidney international, 2000, Volume: 58, Issue:6

    Topics: Aged; Amino Acids; Arginine; Deoxyglucose; Dialysis Solutions; Female; Filtration; Glucans; Glucose; Glycation End Products, Advanced; Glyoxal; Hot Temperature; Humans; Icodextrin; Kidney Failure, Chronic; Lysine; Male; Middle Aged; Peritoneal Dialysis; Peritoneum; Pyruvaldehyde; Sterilization; Time Factors

2000
The impact of salsalate treatment on serum levels of advanced glycation end products in type 2 diabetes.
    Diabetes care, 2014, Volume: 37, Issue:4

    Topics: Adiponectin; Adult; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Pyruvaldehyde; Salicylates

2014
Skin collagen advanced glycation endproducts (AGEs) and the long-term progression of sub-clinical cardiovascular disease in type 1 diabetes.
    Cardiovascular diabetology, 2015, Sep-05, Volume: 14

    Topics: Adult; Arginine; Asymptomatic Diseases; Biomarkers; Biopsy; Cardiovascular Diseases; Carotid Artery Diseases; Carotid Intima-Media Thickness; Chi-Square Distribution; Collagen; Coronary Artery Disease; Diabetes Mellitus, Type 1; Disease Progression; Female; Glycation End Products, Advanced; Glycosylation; Heart Diseases; Humans; Logistic Models; Lysine; Magnetic Resonance Imaging; Male; Multivariate Analysis; Odds Ratio; Pepsin A; Pyruvaldehyde; Risk Factors; Skin; Time Factors; Vascular Calcification; Young Adult

2015
Serum Levels of Protein-Bound Methylglyoxal-Derived Hydroimidazolone-1 are Independently Correlated with Asymmetric Dimethylarginine.
    Rejuvenation research, 2019, Volume: 22, Issue:5

    Topics: Aged; Arginine; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Glucose Intolerance; Glycation End Products, Advanced; Humans; Hypoglycemic Agents; Imidazoles; Inflammation; Male; Middle Aged; Protein Binding; Pyruvaldehyde; Vascular Stiffness

2019
The Effects of Taurine Supplementation on Metabolic Profiles, Pentosidine, Soluble Receptor of Advanced Glycation End Products and Methylglyoxal in Adults With Type 2 Diabetes: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Canadian journal of diabetes, 2021, Volume: 45, Issue:1

    Topics: Adult; Arginine; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 2; Dietary Supplements; Double-Blind Method; Female; Follow-Up Studies; Glycation End Products, Advanced; Humans; Lysine; Male; Metabolome; Prognosis; Pyruvaldehyde; Taurine

2021

Other Studies

101 other study(ies) available for arginine and pyruvaldehyde

ArticleYear
The reactions of phenylglyoxal and related reagents with amino acids.
    Journal of biochemistry, 1977, Volume: 81, Issue:2

    Topics: Aldehydes; Amino Acids; Arginine; Chemical Phenomena; Chemistry; Glyoxal; Hydrogen-Ion Concentration; Pyruvaldehyde

1977
A functional arginine residue in NADPH-dependent aldehyde reductase from pig kidney.
    The Journal of biological chemistry, 1979, May-25, Volume: 254, Issue:10

    Topics: Aldehyde Oxidoreductases; Animals; Arginine; Diacetyl; Kidney; Kinetics; NADP; Nicotinamide Mononucleotide; Protein Binding; Pyruvaldehyde; Spectrophotometry; Swine

1979
Role of nascent alpha-ketoaldehyde in substrate-dependent oxidative inactivation of aldolase.
    European journal of biochemistry, 1978, Jul-17, Volume: 88, Issue:1

    Topics: Aldehydes; Animals; Arginine; Binding Sites; Fructose-Bisphosphate Aldolase; Fructosephosphates; Kinetics; Muscles; Organophosphorus Compounds; Pyruvaldehyde; Rabbits

1978
Significance of fibrin formation and dissolution in the pathogenesis and treatment of cancer.
    Medical hypotheses, 1991, Volume: 36, Issue:4

    Topics: Arginine; Fibrin; Fibrinolysis; Humans; Models, Biological; Neoplasms; Pyruvaldehyde; Sulfhydryl Compounds; Transglutaminases

1991
Arginine residues are involved in the transport function of bilitranslocase.
    Biochimica et biophysica acta, 1990, Jun-27, Volume: 1025, Issue:2

    Topics: Anions; Arginine; Bilirubin; Biological Transport; Cell Membrane; Ceruloplasmin; Liver; Membrane Potentials; Membrane Proteins; Phenylglyoxal; Pyruvaldehyde; Sulfobromophthalein

1990
Labeling of a specific arginine residue at the active site of glutamine synthetase (E.coli).
    Biochemical and biophysical research communications, 1985, Jan-16, Volume: 126, Issue:1

    Topics: Arginine; Binding Sites; Escherichia coli; Glutamate-Ammonia Ligase; Magnesium; Phenylglyoxal; Pyruvaldehyde; Time Factors

1985
Metabolism of glycerate-2,3-P2-III. Arginine-specific reagents inactivate the phosphoglycerate mutase, glycerate-2,3-P2 synthase and glycerate-2,3-P2 phosphatase activities of rabbit muscle phosphoglycerate mutase.
    Comparative biochemistry and physiology. B, Comparative biochemistry, 1983, Volume: 76, Issue:1

    Topics: Animals; Arginine; Cyclohexanones; Diacetyl; Glyoxal; Hydroxylamine; Hydroxylamines; Muscles; Phenylglyoxal; Phosphoglycerate Mutase; Phosphoric Monoester Hydrolases; Phosphotransferases; Pyruvaldehyde; Rabbits

1983
Permeability of inner mitochondrial membrane to arginine reagents.
    FEBS letters, 1982, Aug-02, Volume: 144, Issue:2

    Topics: Animals; Arginine; Cyclohexanones; Diacetyl; Hydroxybutyrate Dehydrogenase; In Vitro Techniques; Intracellular Membranes; Membrane Proteins; Mitochondria; Permeability; Phenylglyoxal; Pyruvaldehyde; Rats; Submitochondrial Particles

1982
Studies on the inactivation of glyceraldehyde-3-phosphate dehydrogenase by methylglyoxal.
    Experientia, 1981, May-15, Volume: 37, Issue:5

    Topics: Aldehydes; Animals; Arginine; Glyceraldehyde-3-Phosphate Dehydrogenases; Kinetics; Muscles; NAD; Protein Binding; Pyruvaldehyde; Rabbits

1981
Modification of essential arginine residues of pigeon liver malic enzyme.
    Biochimica et biophysica acta, 1981, Aug-13, Volume: 660, Issue:2

    Topics: Animals; Arginine; Columbidae; Diacetyl; Kinetics; Liver; Malate Dehydrogenase; NADP; Pentanones; Phenylglyoxal; Protein Binding; Pyruvaldehyde

1981
Involvement of arginine residue in the phosphate binding site of human placental alkaline phosphatase.
    The International journal of biochemistry, 1981, Volume: 13, Issue:11

    Topics: Alkaline Phosphatase; Arginine; Binding Sites; Diacetyl; Female; Humans; In Vitro Techniques; Kinetics; Phenylglyoxal; Phosphates; Placenta; Pregnancy; Pyruvaldehyde

1981
Binding and modification of proteins by methylglyoxal under physiological conditions. A kinetic and mechanistic study with N alpha-acetylarginine, N alpha-acetylcysteine, and N alpha-acetyllysine, and bovine serum albumin.
    The Journal of biological chemistry, 1994, Dec-23, Volume: 269, Issue:51

    Topics: Acetylcysteine; Arginine; Kinetics; Lysine; Protein Binding; Pyruvaldehyde; Serum Albumin, Bovine

1994
Binding of methylglyoxal to albumin and formation of fluorescent adducts. Inhibition by arginine, N-alpha-acetylarginine and aminoguanidine.
    Biochemical Society transactions, 1993, Volume: 21, Issue:2

    Topics: Animals; Arginine; Cattle; Fluorescence; Guanidines; Humans; Protein Binding; Pyruvaldehyde; Rats; Serum Albumin, Bovine

1993
Inactivation of histidine ammonia-lyase from Streptomyces griseus by dicarbonyl reagents.
    Biochimica et biophysica acta, 1993, Jun-04, Volume: 1163, Issue:3

    Topics: Amino Acid Sequence; Amino Acids; Arginine; Binding Sites; Histidine Ammonia-Lyase; Histidinol; Molecular Sequence Data; Phenylglyoxal; Pyruvaldehyde; Sequence Homology, Amino Acid; Streptomyces griseus

1993
Molecular characteristics of methylglyoxal-modified bovine and human serum albumins. Comparison with glucose-derived advanced glycation endproduct-modified serum albumins.
    Journal of protein chemistry, 1995, Volume: 14, Issue:5

    Topics: Animals; Arginine; Cattle; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Glucose; Glycation End Products, Advanced; Humans; Lysine; Molecular Weight; Pyruvaldehyde; Serum Albumin; Serum Albumin, Bovine; Sodium Dodecyl Sulfate; Spectrometry, Fluorescence

1995
Methylglyoxal-modified arginine residues--a signal for receptor-mediated endocytosis and degradation of proteins by monocytic THP-1 cells.
    Biochimica et biophysica acta, 1997, Mar-27, Volume: 1356, Issue:1

    Topics: Arginine; Binding, Competitive; Humans; Ligands; Membrane Proteins; Prothrombin; Pyruvaldehyde; Receptors, Cell Surface; Serum Albumin; Temperature; Tumor Cells, Cultured

1997
Novel amino acid metabolite produced by Streptomyces sp.: I. Taxonomy, isolation, and structural elucidation.
    Bioscience, biotechnology, and biochemistry, 1997, Volume: 61, Issue:6

    Topics: Absorption; Amino Acids; Arginine; Chromatography, High Pressure Liquid; Culture Media; Imidazoles; Ion Exchange Resins; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Microscopy, Electron, Scanning; Ornithine; Pyruvaldehyde; Spectrometry, Mass, Fast Atom Bombardment; Streptomyces

1997
Protein modification by a Maillard reaction intermediate methylglyoxal. Immunochemical detection of fluorescent 5-methylimidazolone derivatives in vivo.
    FEBS letters, 1997, Jun-30, Volume: 410, Issue:2-3

    Topics: Animals; Antibodies; Aorta; Arginine; Arteriosclerosis; Hemocyanins; Humans; Imidazoles; Lysine; Maillard Reaction; Molecular Structure; Pyruvaldehyde; Rabbits; Serum Albumin, Bovine

1997
Protein modification by methylglyoxal: chemical nature and synthetic mechanism of a major fluorescent adduct.
    Archives of biochemistry and biophysics, 1997, Aug-01, Volume: 344, Issue:1

    Topics: Animals; Arginine; Cattle; Chromatography, High Pressure Liquid; Crystallins; Glyceraldehyde; Guanidines; Kinetics; Maillard Reaction; Molecular Structure; Monosaccharides; Ornithine; Proteins; Pyrimidines; Pyruvaldehyde; Spectrometry, Fluorescence; Spectrophotometry

1997
Synthesis and secretion of tumour necrosis factor-alpha by human monocytic THP-1 cells and chemotaxis induced by human serum albumin derivatives modified with methylglyoxal and glucose-derived advanced glycation endproducts.
    Immunology letters, 1997, Volume: 58, Issue:3

    Topics: Arginine; Chemotaxis, Leukocyte; Cystine; Glycation End Products, Advanced; Humans; Lysine; Monocytes; Pyruvaldehyde; Serum Albumin; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1997
Identification of cysteine and arginine residues essential for the phosphotransacetylase from Methanosarcina thermophila.
    Journal of bacteriology, 1997, Volume: 179, Issue:24

    Topics: Amino Acid Sequence; Archaeal Proteins; Arginine; Bacteria, Anaerobic; Binding Sites; Coenzyme A; Cysteine; Ethylmaleimide; Methanosarcina; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphate Acetyltransferase; Pyruvaldehyde; Recombinant Proteins; Sequence Analysis; Sequence Homology, Amino Acid; Species Specificity

1997
Immunohistochemical detection of imidazolone and N(epsilon)-(carboxymethyl)lysine in aortas of hemodialysis patients.
    Cellular and molecular biology (Noisy-le-Grand, France), 1998, Volume: 44, Issue:7

    Topics: Aged; Aorta; Arginine; Arteriosclerosis; Deoxyglucose; Female; Glyoxal; Humans; Imidazoles; Immunohistochemistry; Lysine; Male; Middle Aged; Pyruvaldehyde; Renal Dialysis; Uremia

1998
Chemical modification of proteins by methylglyoxal.
    Cellular and molecular biology (Noisy-le-Grand, France), 1998, Volume: 44, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Animals; Aorta; Arginine; Child; Collagen; Crystallins; Diabetes Mellitus, Type 1; Dogs; Glycation End Products, Advanced; Humans; Lens, Crystalline; Lysine; Maillard Reaction; Middle Aged; Proteins; Pyruvaldehyde; Rats; Skin; Uremia

1998
Increase in three alpha,beta-dicarbonyl compound levels in human uremic plasma: specific in vivo determination of intermediates in advanced Maillard reaction.
    Biochemical and biophysical research communications, 1999, Mar-05, Volume: 256, Issue:1

    Topics: 2-Naphthylamine; Aging; Arginine; Chromatography, Liquid; Deoxyglucose; Diabetes Mellitus, Type 2; Glycation End Products, Advanced; Glyoxal; Humans; Kidney Failure, Chronic; Lysine; Mass Spectrometry; Matched-Pair Analysis; Middle Aged; Pyruvaldehyde; Reactive Oxygen Species; Sensitivity and Specificity; Uremia

1999
Methylglyoxal modification of protein. Chemical and immunochemical characterization of methylglyoxal-arginine adducts.
    The Journal of biological chemistry, 1999, Jun-25, Volume: 274, Issue:26

    Topics: Animals; Antibodies, Monoclonal; Arginine; Brain Chemistry; Chromatography, High Pressure Liquid; Diabetes Mellitus; Enzyme-Linked Immunosorbent Assay; Female; Humans; Kidney; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred BALB C; Models, Chemical; Ornithine; Proteins; Pyrimidines; Pyruvaldehyde; Rats

1999
Cross-linking of proteins by Maillard processes: characterization and detection of lysine-arginine cross-links derived from glyoxal and methylglyoxal.
    Bioorganic & medicinal chemistry, 1999, Volume: 7, Issue:11

    Topics: Arginine; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Glyoxal; Imidazoles; Lysine; Magnetic Resonance Spectroscopy; Maillard Reaction; Pyruvaldehyde; Serum Albumin, Bovine

1999
Modulation of plasminogen activation and plasmin activity by methylglyoxal modification of the zymogen.
    Biochimica et biophysica acta, 2000, Jul-14, Volume: 1480, Issue:1-2

    Topics: Animals; Arginine; Catalysis; Electrophoresis, Polyacrylamide Gel; Fibrinolysin; Fibrinolysis; Kinetics; Lysine; Male; Plasminogen; Pyruvaldehyde; Rats; Rats, Wistar; Spectrometry, Fluorescence

2000
Mechanism of the inhibitory effect of OPB-9195 [(+/-)-2-isopropylidenehydrazono-4-oxo-thiazolidin-5-yla cetanilide] on advanced glycation end product and advanced lipoxidation end product formation.
    Journal of the American Society of Nephrology : JASN, 2000, Volume: 11, Issue:9

    Topics: Aldehydes; Arachidonic Acid; Arginine; Deoxyglucose; Dialysis Solutions; Glycation End Products, Advanced; Glyoxal; Guanidines; Lipid Metabolism; Lysine; Malondialdehyde; Oxidation-Reduction; Peritoneal Dialysis; Prodrugs; Pyruvaldehyde; Thiadiazoles; Thiazolidines

2000
Chromatographic quantification of argpyrimidine, a methylglyoxal-derived product in tissue proteins: comparison with pentosidine.
    Analytical biochemistry, 2001, Volume: 290, Issue:2

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Arginine; Blood Proteins; Diabetes Mellitus; Humans; Lens, Crystalline; Lysine; Middle Aged; Ornithine; Pyrimidines; Pyruvaldehyde

2001
Role of iron in the interaction of red blood cells with methylglyoxal. Modification of L-arginine by methylglyoxal is catalyzed by iron redox cycling.
    Chemico-biological interactions, 2001, Nov-28, Volume: 138, Issue:2

    Topics: Arginine; Calcium; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Erythrocytes; Ferric Compounds; Ferrous Compounds; Free Radicals; Humans; In Vitro Techniques; Iron; Oxidation-Reduction; Oxidative Stress; Pyruvaldehyde; Quaternary Ammonium Compounds

2001
Crosslinking by advanced glycation end products increases the stiffness of the collagen network in human articular cartilage: a possible mechanism through which age is a risk factor for osteoarthritis.
    Arthritis and rheumatism, 2002, Volume: 46, Issue:1

    Topics: Adult; Aging; Arginine; Cartilage, Articular; Collagen; Cross-Linking Reagents; Glycation End Products, Advanced; Humans; Lysine; Osteoarthritis; Pyruvaldehyde; Regression Analysis; Ribose; Stress, Mechanical; Tetroses

2002
Effect of pyridoxamine on chemical modification of proteins by carbonyls in diabetic rats: characterization of a major product from the reaction of pyridoxamine and methylglyoxal.
    Archives of biochemistry and biophysics, 2002, Jun-01, Volume: 402, Issue:1

    Topics: Animals; Arginine; Cattle; Chromatography, High Pressure Liquid; Crystallins; Diabetes Mellitus, Experimental; Dimerization; Erythrocytes; Glutathione; Glycation End Products, Advanced; Lactoylglutathione Lyase; Lysine; Magnetic Resonance Spectroscopy; Maillard Reaction; Models, Chemical; Oxidative Stress; Pyridoxamine; Pyruvaldehyde; Rats; Rats, Sprague-Dawley; Thiobarbituric Acid Reactive Substances

2002
Improved superoxide-generating system suitable for the assessment of the superoxide-scavenging ability of aqueous extracts of food constituents using ultraweak chemiluminescence.
    Journal of agricultural and food chemistry, 2003, Jan-01, Volume: 51, Issue:1

    Topics: Acridines; Arginine; Food Analysis; Free Radical Scavengers; Hydrogen-Ion Concentration; Kinetics; Luminescent Measurements; Pyruvaldehyde; Solutions; Superoxides; Water

2003
Identification of the binding site of methylglyoxal on glutathione peroxidase: methylglyoxal inhibits glutathione peroxidase activity via binding to glutathione binding sites Arg 184 and 185.
    Free radical research, 2003, Volume: 37, Issue:2

    Topics: Amino Acid Sequence; Animals; Arginine; Binding Sites; Cattle; Cells, Cultured; Chromatography, High Pressure Liquid; Deoxyglucose; Erythrocytes; Glutathione; Glutathione Peroxidase; Glyoxal; Mass Spectrometry; Metalloendopeptidases; Molecular Sequence Data; Muscle, Smooth; Oxidative Stress; Peptides; Phenylglyoxal; Protein Binding; Pyruvaldehyde; Rats; Selenocysteine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Time Factors

2003
Enhancement of chaperone function of alpha-crystallin by methylglyoxal modification.
    Biochemistry, 2003, Sep-16, Volume: 42, Issue:36

    Topics: Alcohol Dehydrogenase; alpha-Crystallins; Anilino Naphthalenesulfonates; Animals; Arginine; Ascorbic Acid; Cattle; Citrate (si)-Synthase; Humans; Insulin; Lens, Crystalline; Lysine; Middle Aged; Molecular Chaperones; Monosaccharides; Ornithine; Protein Structure, Secondary; Protein Structure, Tertiary; Pyrimidines; Pyruvaldehyde

2003
Methylglyoxal-derived hydroimidazolone advanced glycation end-products of human lens proteins.
    Investigative ophthalmology & visual science, 2003, Volume: 44, Issue:12

    Topics: Aged; Arginine; Cataract; Chromatography, High Pressure Liquid; Crystallins; Female; Fluorometry; Glycation End Products, Advanced; Humans; Hydrolysis; Imidazoles; Lens, Crystalline; Lysine; Male; Mass Spectrometry; Middle Aged; Pyruvaldehyde

2003
Evaluation of advanced glycation end products and carbonyl compounds in patients with different conditions of oxidative stress.
    Molecular nutrition & food research, 2005, Volume: 49, Issue:7

    Topics: Aged; Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Dialysis Solutions; Glycated Hemoglobin; Glycation End Products, Advanced; Glyoxal; Humans; Kidney Failure, Chronic; Lysine; Middle Aged; Oxidative Stress; Peritoneal Dialysis; Pyruvaldehyde

2005
Peptide mapping of human serum albumin modified minimally by methylglyoxal in vitro and in vivo.
    Annals of the New York Academy of Sciences, 2005, Volume: 1043

    Topics: Arginine; Binding Sites; Crystallography, X-Ray; Glycation End Products, Advanced; Humans; Models, Molecular; Molecular Weight; Peptide Mapping; Protein Conformation; Pyruvaldehyde; Serum Albumin

2005
Mechanism of perturbation of integrin-mediated cell-matrix interactions by reactive carbonyl compounds and its implication for pathogenesis of diabetic nephropathy.
    Diabetes, 2005, Volume: 54, Issue:10

    Topics: Aldehydes; Arginine; Binding Sites; Cell Adhesion; Cell Physiological Phenomena; Collagen Type IV; Diabetic Nephropathies; Endothelial Cells; Extracellular Matrix; Extracellular Matrix Proteins; Glucose; Glyoxal; Humans; Integrin alphaVbeta3; Integrins; Kidney; Kidney Glomerulus; Pyridoxamine; Pyruvaldehyde; Umbilical Veins

2005
Effect of site-directed mutagenesis of methylglyoxal-modifiable arginine residues on the structure and chaperone function of human alphaA-crystallin.
    Biochemistry, 2006, Apr-11, Volume: 45, Issue:14

    Topics: alpha-Crystallin A Chain; Arginine; Carbonic Anhydrases; Circular Dichroism; Humans; Molecular Chaperones; Mutagenesis, Site-Directed; Protein Structure, Secondary; Pyruvaldehyde; Spectrometry, Fluorescence

2006
The effect of chemical modification of amino acid side-chains on collagen degradation by enzymes.
    Journal of biomedical materials research. Part B, Applied biomaterials, 2007, Volume: 81, Issue:1

    Topics: Amino Acids; Animals; Arginine; Biocompatible Materials; Cattle; Chromatography, Gel; Collagen Type I; Endopeptidases; Epoxy Compounds; Lysine; Propanols; Pyruvaldehyde; Solubility

2007
Pyridoxamine inhibits maillard reactions in diabetic rat lenses.
    Ophthalmic research, 2006, Volume: 38, Issue:5

    Topics: Aldehyde Reductase; Animals; Arginine; Chromatography, High Pressure Liquid; Diabetes Complications; Diabetes Mellitus, Experimental; Glucose; Glutathione; Glycation End Products, Advanced; Lactoylglutathione Lyase; Lens Diseases; Lens, Crystalline; Lysine; Maillard Reaction; Male; Organ Culture Techniques; Ornithine; Pyridoxamine; Pyrimidines; Pyruvaldehyde; Rats; Rats, Sprague-Dawley

2006
Detection and identification of arginine modifications on methylglyoxal-modified ribonuclease by mass spectrometric analysis.
    Journal of mass spectrometry : JMS, 2007, Volume: 42, Issue:1

    Topics: Amino Acid Sequence; Arginine; Exoribonucleases; Kinetics; Molecular Sequence Data; Peptide Fragments; Pyruvaldehyde; Serine Endopeptidases; Spectrometry, Mass, Electrospray Ionization; Trypsin

2007
Site-selective modifications of arginine residues in human hemoglobin induced by methylglyoxal.
    Biochemistry, 2006, Dec-26, Volume: 45, Issue:51

    Topics: Amino Acid Sequence; Arginine; Chromatography, Liquid; Hemoglobins; Humans; Imidazoles; Molecular Sequence Data; Protein Subunits; Pyruvaldehyde; Surface Properties; Tandem Mass Spectrometry

2006
Methylglyoxal inhibits the binding step of collagen phagocytosis.
    The Journal of biological chemistry, 2007, Mar-16, Volume: 282, Issue:11

    Topics: Amino Acids; Animals; Arginine; Cell Adhesion; Collagen; Fibroblasts; Humans; Integrin alpha2beta1; Lysine; Periodontitis; Phagocytosis; Protein Binding; Pyruvaldehyde; Rats; Signal Transduction

2007
Methylglyoxal inhibits glycation-mediated loss in chaperone function and synthesis of pentosidine in alpha-crystallin.
    Experimental eye research, 2007, Volume: 84, Issue:5

    Topics: alpha-Crystallins; Animals; Arginine; Cattle; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Eye Proteins; Glycosylation; Lens, Crystalline; Lysine; Molecular Chaperones; Organ Culture Techniques; Pyruvaldehyde; Rats

2007
Methylglyoxal induces advanced glycation end product (AGEs) formation and dysfunction of PDGF receptor-beta: implications for diabetic atherosclerosis.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2007, Volume: 21, Issue:12

    Topics: Animals; Aorta; Apolipoproteins E; Arginine; Atherosclerosis; Becaplermin; Cell Movement; Cell Proliferation; Cells, Cultured; Diabetes Complications; Diabetes Mellitus, Experimental; Glycation End Products, Advanced; Glyoxal; Guanidines; Humans; Mesoderm; Mice; Mice, Knockout; Myocytes, Smooth Muscle; Platelet-Derived Growth Factor; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-sis; Pyruvaldehyde; Rabbits; Receptor, Platelet-Derived Growth Factor beta

2007
High glucose increases angiopoietin-2 transcription in microvascular endothelial cells through methylglyoxal modification of mSin3A.
    The Journal of biological chemistry, 2007, Oct-19, Volume: 282, Issue:42

    Topics: Acetylglucosamine; Angiopoietin-2; Animals; Arginine; Cell Line, Transformed; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Endothelial Cells; Gene Expression Regulation; Glucose; Glycolysis; Intercellular Adhesion Molecule-1; Kidney; Mice; N-Acetylglucosaminyltransferases; Protein Processing, Post-Translational; Pyruvaldehyde; Repressor Proteins; Response Elements; Sin3 Histone Deacetylase and Corepressor Complex; Sp3 Transcription Factor; Sweetening Agents; Transcription, Genetic; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1

2007
Methylglyoxal and methylglyoxal-arginine adducts do not directly inhibit endothelial nitric oxide synthase.
    Annals of the New York Academy of Sciences, 2008, Volume: 1126

    Topics: Anthracenes; Arginine; Endothelium, Vascular; Enzyme Inhibitors; Humans; Nitric Oxide Synthase Type III; Propane; Pyruvaldehyde; Umbilical Veins

2008
Effects of cross-link breakers, glycation inhibitors and insulin sensitisers on HDL function and the non-enzymatic glycation of apolipoprotein A-I.
    Diabetologia, 2008, Volume: 51, Issue:6

    Topics: Apolipoprotein A-I; Arginine; Cross-Linking Reagents; Glycosylation; Guanidines; Humans; Lipoproteins, HDL; Lysine; Metformin; Phosphatidylcholine-Sterol O-Acyltransferase; Pyridoxamine; Pyruvaldehyde; Thiazoles; Tryptophan

2008
Modification of vimentin: a general mechanism of nonenzymatic glycation in human skin.
    Annals of the New York Academy of Sciences, 2008, Volume: 1126

    Topics: Arginine; Blotting, Western; Cells, Cultured; Face; Glycation End Products, Advanced; Glycosylation; Glyoxal; Humans; Lysine; Norleucine; Pyrroles; Pyruvaldehyde; Skin; Vimentin

2008
The formation of argpyrimidine, a methylglyoxal-arginine adduct, in the nucleus of neural cells.
    Biochemical and biophysical research communications, 2009, Jan-09, Volume: 378, Issue:2

    Topics: Animals; Arginine; Cell Nucleus; Cerebral Cortex; DNA Adducts; Lactoylglutathione Lyase; Mice; Mice, Inbred ICR; Neurons; Ornithine; Pyrimidines; Pyruvaldehyde

2009
Critical evaluation of toxic versus beneficial effects of methylglyoxal.
    Biochemistry. Biokhimiia, 2009, Volume: 74, Issue:10

    Topics: Animals; Arginine; Cataract; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Drug Delivery Systems; Glycation End Products, Advanced; Humans; Kidney Failure, Chronic; Lysine; Maillard Reaction; Oxidative Stress; Protein Conformation; Protein Folding; Pyruvaldehyde; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serum Albumin

2009
Formation of arginine modifications in a model system of Nα-tert-butoxycarbonyl (Boc)-arginine with methylglyoxal.
    Journal of agricultural and food chemistry, 2011, Jan-12, Volume: 59, Issue:1

    Topics: Arginine; Food Additives; Kinetics; Models, Chemical; Pyruvaldehyde

2011
Glucose autoxidation induces functional damage to proteins via modification of critical arginine residues.
    Biochemistry, 2011, Jul-12, Volume: 50, Issue:27

    Topics: Amino Acid Motifs; Animals; Arginine; Collagen Type IV; Diabetes Mellitus, Experimental; Glucose; Glyoxal; Hyperglycemia; Male; Micrococcus; Muramidase; Protein Carbonylation; Protein Structure, Tertiary; Proteins; Pyruvaldehyde; Random Allocation; Rats; Rats, Sprague-Dawley

2011
Dual effects of phloretin and phloridzin on the glycation induced by methylglyoxal in model systems.
    Chemical research in toxicology, 2011, Aug-15, Volume: 24, Issue:8

    Topics: Acetylcysteine; Amino Acid Sequence; Arginine; Creatine Kinase; Lysine; Models, Molecular; Peptides; Phloretin; Phlorhizin; Protein Binding; Pyruvaldehyde; Spectrometry, Mass, Electrospray Ionization

2011
Hydroimidazolone modification of the conserved Arg12 in small heat shock proteins: studies on the structure and chaperone function using mutant mimics.
    PloS one, 2012, Volume: 7, Issue:1

    Topics: alpha-Crystallin A Chain; alpha-Crystallin B Chain; Amino Acid Sequence; Arginine; Binding Sites; Circular Dichroism; Electrophoresis, Polyacrylamide Gel; HSP27 Heat-Shock Proteins; Imidazoles; Kinetics; Molecular Chaperones; Molecular Sequence Data; Molecular Structure; Mutation; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Pyruvaldehyde; Recombinant Proteins; Sequence Homology, Amino Acid; Spectrometry, Fluorescence; Thermodynamics

2012
Comparative DFT study to determine if α-oxoaldehydes are precursors for pentosidine formation.
    The journal of physical chemistry. A, 2012, Mar-22, Volume: 116, Issue:11

    Topics: Arginine; Glycosylation; Glyoxal; Imidazoles; Kinetics; Lysine; Molecular Structure; Pyruvaldehyde; Quantum Theory; Schiff Bases; Thermodynamics; Water

2012
Arginine attenuates methylglyoxal- and high glucose-induced endothelial dysfunction and oxidative stress by an endothelial nitric-oxide synthase-independent mechanism.
    The Journal of pharmacology and experimental therapeutics, 2012, Volume: 342, Issue:1

    Topics: Animals; Aorta; Arginase; Arginine; Cells, Cultured; Endothelial Cells; Endothelium, Vascular; Glucose; Human Umbilical Vein Endothelial Cells; Humans; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidase 4; NADPH Oxidases; NF-kappa B; Nitric Oxide Synthase Type III; Oxidative Stress; Pyruvaldehyde; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Vascular Diseases; Vasodilation

2012
Exploring post-translational arginine modification using chemically synthesized methylglyoxal hydroimidazolones.
    Journal of the American Chemical Society, 2012, May-30, Volume: 134, Issue:21

    Topics: Amino Acid Sequence; Arginine; Imidazoles; Isomerism; Oligopeptides; Protein Processing, Post-Translational; Pyruvaldehyde

2012
Maternal plasma advanced glycation end products concentrations in response to oral 50-gram glucose load in mid-pregnancy: a pilot study.
    Clinical laboratory, 2012, Volume: 58, Issue:9-10

    Topics: Adult; Arginine; Chromatography, High Pressure Liquid; Female; Glucose; Glucose Tolerance Test; Glycation End Products, Advanced; Humans; Hyperglycemia; Lysine; Mass Spectrometry; Pilot Projects; Pregnancy; Pregnancy Trimester, Second; Prospective Studies; Pyruvaldehyde

2012
Glycation of human erythrocyte glutathione peroxidase: effect on the physical and kinetic properties.
    Clinica chimica acta; international journal of clinical chemistry, 2013, Jun-05, Volume: 421

    Topics: Amino Acid Sequence; Arginine; Binding Sites; Circular Dichroism; Erythrocytes; Glutathione Peroxidase; Glyceraldehyde; Glycosylation; Humans; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Peptide Fragments; Protein Binding; Pyruvaldehyde; Solutions; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Temperature

2013
Methylglyoxal-induced modification of arginine residues decreases the activity of NADPH-generating enzymes.
    Free radical biology & medicine, 2013, Volume: 61

    Topics: Amino Acid Sequence; Arginine; Glucosephosphate Dehydrogenase; Glycation End Products, Advanced; Isocitrate Dehydrogenase; Malate Dehydrogenase; Molecular Sequence Data; NADP; Pyruvaldehyde

2013
Reactive metabolites and AGE-RAGE-mediated inflammation in patients following liver transplantation.
    Mediators of inflammation, 2013, Volume: 2013

    Topics: Antioxidants; Arginine; Female; Glycation End Products, Advanced; Humans; Inflammation; Liver Transplantation; Male; Models, Biological; Pyruvaldehyde; Receptor for Advanced Glycation End Products; Receptors, Immunologic

2013
Arginine modifications by methylglyoxal: discovery in a recombinant monoclonal antibody and contribution to acidic species.
    Analytical chemistry, 2013, Dec-03, Volume: 85, Issue:23

    Topics: Animals; Antibodies, Monoclonal; Antiporters; Arginine; CHO Cells; Cricetinae; Cricetulus; Mass Spectrometry; Pyruvaldehyde; Recombinant Proteins

2013
Perturbation of human coronary artery endothelial cell redox state and NADPH generation by methylglyoxal.
    PloS one, 2014, Volume: 9, Issue:1

    Topics: Aldehydes; Arginine; Cells, Cultured; Coronary Vessels; Endothelial Cells; Glucose-6-Phosphate; Glutathione; Glycation End Products, Advanced; Humans; NADP; Oxidation-Reduction; Pyruvaldehyde; Sulfhydryl Compounds

2014
Advanced glycation end products of beta2-microglobulin in uremic patients as determined by high resolution mass spectrometry.
    Journal of pharmaceutical and biomedical analysis, 2014, Volume: 91

    Topics: Acrolein; Aldehydes; Arginine; beta 2-Microglobulin; Glucose; Glycation End Products, Advanced; Glyoxal; Humans; Mass Spectrometry; Pyruvaldehyde; Uremia

2014
Potential of birds to serve as pathology-free models of type 2 diabetes, part 2: do high levels of carbonyl-scavenging amino acids (e.g., taurine) and low concentrations of methylglyoxal limit the production of advanced glycation end-products?
    Rejuvenation research, 2014, Volume: 17, Issue:4

    Topics: Albumins; Animals; Arginine; Birds; Diabetes Mellitus, Type 2; Disease Models, Animal; Fructosamine; Glucose; Glycation End Products, Advanced; Lysine; Maillard Reaction; Pyruvaldehyde; Taurine

2014
A model study for tethering of (bio)active molecules to biomaterial surfaces through arginine.
    Organic & biomolecular chemistry, 2014, Jun-28, Volume: 12, Issue:24

    Topics: Animals; Arginine; Biocompatible Materials; Collagen; Guanidine; Horses; Ketones; Lactose; Pyruvaldehyde; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Surface Properties

2014
Triple negative tumors accumulate significantly less methylglyoxal specific adducts than other human breast cancer subtypes.
    Oncotarget, 2014, Jul-30, Volume: 5, Issue:14

    Topics: Arginine; Cell Line, Tumor; Female; Glycation End Products, Advanced; Humans; Immunohistochemistry; Lactoylglutathione Lyase; MCF-7 Cells; Pyrimidines; Pyruvaldehyde; Triple Negative Breast Neoplasms

2014
Parkinsonism-associated protein DJ-1/Park7 is a major protein deglycase that repairs methylglyoxal- and glyoxal-glycated cysteine, arginine, and lysine residues.
    The Journal of biological chemistry, 2015, Jan-16, Volume: 290, Issue:3

    Topics: Acetylcysteine; Albumins; Apoptosis; Arginine; Aspartate Aminotransferases; Catalysis; Cell Survival; Cysteine; Escherichia coli; Fructose-Bisphosphate Aldolase; Glucose; Glycolates; Glyoxal; Humans; Intracellular Signaling Peptides and Proteins; Lactates; Lysine; Mass Spectrometry; Oncogene Proteins; Oxidative Stress; Parkinsonian Disorders; Protein Deglycase DJ-1; Pyruvaldehyde

2015
Influence of nonenzymatic posttranslational modifications on constitution, oligomerization and receptor binding of S100A12.
    PloS one, 2014, Volume: 9, Issue:11

    Topics: Amination; Animals; Arginine; Humans; Imidazoles; Kinetics; Lysine; Mice; Protein Binding; Protein Conformation; Protein Multimerization; Protein Processing, Post-Translational; Pyrimidines; Pyruvaldehyde; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Recombinant Proteins; S100 Proteins; S100A12 Protein; Solutions

2014
The DJ-1 superfamily member Hsp31 repairs proteins from glycation by methylglyoxal and glyoxal.
    Biochemical and biophysical research communications, 2015, Aug-07, Volume: 463, Issue:4

    Topics: Arginine; Cysteine; Escherichia coli Proteins; Glucose; Glyceraldehyde-3-Phosphate Dehydrogenases; Glyoxal; Lysine; Molecular Chaperones; Pyruvaldehyde; Schiff Bases

2015
Site specific modification of the human plasma proteome by methylglyoxal.
    Toxicology and applied pharmacology, 2015, Dec-01, Volume: 289, Issue:2

    Topics: Arginine; Binding Sites; Biomarkers; Blood Proteins; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Female; High-Throughput Screening Assays; Humans; Male; Peptide Mapping; Protein Binding; Protein Carbonylation; Protein Processing, Post-Translational; Proteomics; Pyruvaldehyde; Serum Albumin; Serum Albumin, Human; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2015
Arg354 in the catalytic centre of bovine liver catalase is protected from methylglyoxal-mediated glycation.
    BMC research notes, 2015, Dec-30, Volume: 8

    Topics: Amino Acid Sequence; Animals; Arginine; Catalase; Catalytic Domain; Cattle; Chromatography, High Pressure Liquid; Glycosylation; Liver; Pyruvaldehyde; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2015
Effect of hydroxytyrosol and olive leaf extract on 1,2-dicarbonyl compounds, hydroxymethylfurfural and advanced glycation endproducts in a biscuit model.
    Food chemistry, 2017, Feb-15, Volume: 217

    Topics: Arginine; Chromatography, Liquid; Deoxyglucose; Flour; Food Handling; Furaldehyde; Gallic Acid; Glycation End Products, Advanced; Lysine; Maillard Reaction; Olea; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Pyruvaldehyde; Quercetin; Tandem Mass Spectrometry; Triticum

2017
Interaction of free arginine and guanidine with glucose under thermal processing conditions and formation of Amadori-derived imidazolones.
    Food chemistry, 2017, Apr-01, Volume: 220

    Topics: Arginine; Glucose; Guanidine; Imidazoles; Pyruvaldehyde; Tandem Mass Spectrometry

2017
Hydrodynamic sample injection into short electrophoretic capillary in systems with a flow-gating interface.
    Journal of chromatography. A, 2017, Jan-13, Volume: 1480

    Topics: Arginine; Biguanides; Electrophoresis, Capillary; Hydrodynamics; Hypoglycemic Agents; Microdialysis; Potassium; Pyruvaldehyde; Sodium; Solutions; Time Factors

2017
Modification of chickpea cystatin by reactive dicarbonyl species: Glycation, oxidation and aggregation.
    Archives of biochemistry and biophysics, 2018, 07-15, Volume: 650

    Topics: Arginine; Cicer; Cystatins; Glycation End Products, Advanced; Glycosylation; Glyoxal; Lysine; Oxidation-Reduction; Plant Proteins; Protein Aggregates; Pyruvaldehyde

2018
Methylglyoxal-derived posttranslational arginine modifications are abundant histone marks.
    Proceedings of the National Academy of Sciences of the United States of America, 2018, 09-11, Volume: 115, Issue:37

    Topics: Arginine; HEK293 Cells; Histones; Humans; Lactoylglutathione Lyase; Protein Processing, Post-Translational; Pyruvaldehyde; Transcription, Genetic

2018
A metabolite-derived protein modification integrates glycolysis with KEAP1-NRF2 signalling.
    Nature, 2018, Volume: 562, Issue:7728

    Topics: Animals; Antioxidant Response Elements; Arginine; Cell Line; Cysteine; Cytoprotection; Glycolysis; Humans; Imidazoles; Kelch-Like ECH-Associated Protein 1; Male; Mice; Mice, Inbred BALB C; NF-E2-Related Factor 2; Phosphoglycerate Kinase; Protein Multimerization; Protein Processing, Post-Translational; Pyruvaldehyde; Signal Transduction; Stress, Physiological; Transcription, Genetic; Ubiquitination

2018
Diabetes with heart failure increases methylglyoxal modifications in the sarcomere, which inhibit function.
    JCI insight, 2018, 10-18, Volume: 3, Issue:20

    Topics: Actins; Adult; Animals; Arginine; Cardiomyopathy, Dilated; Diabetes Mellitus, Type 2; Disease Models, Animal; Female; Glycolysis; Heart Failure; Heart Ventricles; Humans; Lysine; Male; Mice; Middle Aged; Myosins; Pyruvaldehyde; Sarcomeres; Single-Cell Analysis

2018
Dysfunction in nitric oxide synthesis in streptozotocin treated rat aorta and role of methylglyoxal.
    European journal of pharmacology, 2019, Jan-05, Volume: 842

    Topics: Animals; Aorta; Arginine; Blood Glucose; Gene Expression Regulation, Enzymologic; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase Type II; Pyruvaldehyde; Rats; Rats, Wistar; Streptozocin; Vasoconstriction

2019
Methylglyoxal as a prognostic factor in patients with chronic kidney disease.
    Nephrology (Carlton, Vic.), 2019, Volume: 24, Issue:9

    Topics: Aged; Arginine; Biomarkers; Cardiovascular Diseases; Deoxyglucose; Diabetic Nephropathies; Disease Progression; Female; Humans; Japan; Kidney Failure, Chronic; Lysine; Male; Middle Aged; Predictive Value of Tests; Prospective Studies; Pyruvaldehyde; Renal Insufficiency, Chronic; Risk Factors; Time Factors; Up-Regulation

2019
Studies on the Formation of 3-Deoxyglucosone- and Methylglyoxal-Derived Hydroimidazolones of Creatine during Heat Treatment of Meat.
    Journal of agricultural and food chemistry, 2019, May-22, Volume: 67, Issue:20

    Topics: Animals; Arginine; Cattle; Chickens; Chromatography, High Pressure Liquid; Cooking; Creatine; Deoxyglucose; Hot Temperature; Imidazoles; Lysine; Maillard Reaction; Meat; Pyruvaldehyde; Swine; Tandem Mass Spectrometry

2019
Physico-chemical Changes Induced in the Serum Proteins Immunoglobulin G and Fibrinogen Mediated by Methylglyoxal.
    Current protein & peptide science, 2020, Volume: 21, Issue:9

    Topics: Arginine; Benzothiazoles; Fibrinogen; Furaldehyde; Glycation End Products, Advanced; Glycosylation; Humans; Immunoglobulin G; Kinetics; Lysine; Malondialdehyde; Oxidation-Reduction; Protein Carbonylation; Pyruvaldehyde; Solutions; Spectrometry, Fluorescence

2020
Protein arginine deiminase 4 antagonizes methylglyoxal-induced histone glycation.
    Nature communications, 2020, 06-26, Volume: 11, Issue:1

    Topics: Animals; Arginine; Breast Neoplasms; Citrullination; Citrulline; Female; Glycosylation; Histones; Humans; MCF-7 Cells; Methylation; Mice, Inbred BALB C; Mice, Nude; Models, Biological; Nucleosomes; Protein-Arginine Deiminase Type 4; Pyruvaldehyde

2020
Gastrointestinal digestion of dietary advanced glycation endproducts using an in vitro model of the gastrointestinal tract (TIM-1).
    Food & function, 2020, Jul-22, Volume: 11, Issue:7

    Topics: Animals; Arginine; Chromatography, Liquid; Digestion; Fruit and Vegetable Juices; Gastrointestinal Tract; Glycation End Products, Advanced; Glyoxal; Hepatitis A Virus Cellular Receptor 1; Humans; Lysine; Milk; Pyruvaldehyde; Tandem Mass Spectrometry; Zingiber officinale

2020
Comparison of the reaction of methylglyoxal (MGO) with murine and human amyloid beta (Aβ): Insights into a mechanism of Alzheimer's disease (AD).
    Biochemical and biophysical research communications, 2020, 12-17, Volume: 533, Issue:4

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Arginine; Humans; Lysine; Mice; Peptide Fragments; Pyruvaldehyde; Superoxides

2020
Transient elevation of temperature promotes cross-linking of α-crystallin-client proteins through formation of advanced glycation endproducts: A potential role in presbyopia and cataracts.
    Biochemical and biophysical research communications, 2020, 12-17, Volume: 533, Issue:4

    Topics: alpha-Crystallin B Chain; Arginine; Cataract; Citrate (si)-Synthase; Cross-Linking Reagents; Glycation End Products, Advanced; Humans; Malate Dehydrogenase; Multiprotein Complexes; Presbyopia; Pyruvaldehyde; Temperature

2020
Age-dependent accumulation of dicarbonyls and advanced glycation endproducts (AGEs) associates with mitochondrial stress.
    Free radical biology & medicine, 2021, 02-20, Volume: 164

    Topics: Animals; Arginine; Glycation End Products, Advanced; Mice; Mitochondria; Pyruvaldehyde; Reactive Oxygen Species

2021
Arginine glycosylation enhances methylglyoxal detoxification.
    Scientific reports, 2021, 02-15, Volume: 11, Issue:1

    Topics: Arginine; Bacterial Physiological Phenomena; Bacterial Proteins; Chromatography, Liquid; Citrobacter rodentium; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Glycosylation; Inactivation, Metabolic; Metabolome; Models, Biological; Pyruvaldehyde; Tandem Mass Spectrometry; Type III Secretion Systems

2021
Synergistic sequence contributions bias glycation outcomes.
    Nature communications, 2021, 06-03, Volume: 12, Issue:1

    Topics: Amino Acid Sequence; Arginine; Glycation End Products, Advanced; Glycosylation; HEK293 Cells; Humans; Imidazoles; Isomerism; Peptide Library; Protein Processing, Post-Translational; Proteins; Pyruvaldehyde

2021
In Vitro and In Vivo Antiglycation Effects of Connarus ruber Extract.
    Planta medica, 2022, Volume: 88, Issue:12

    Topics: Animals; Arginine; Collagen; Connaraceae; Diabetes Mellitus, Experimental; Glycation End Products, Advanced; Guanidines; Lipids; Lysine; Pyruvaldehyde; Rats; Streptozocin

2022
On the Prediction of In Vitro Arginine Glycation of Short Peptides Using Artificial Neural Networks.
    Sensors (Basel, Switzerland), 2022, Jul-13, Volume: 22, Issue:14

    Topics: Arginine; Glycation End Products, Advanced; Lysine; Neural Networks, Computer; Peptides; Proteins; Pyruvaldehyde

2022
Studies on the Reaction of Dietary Methylglyoxal and Creatine during Simulated Gastrointestinal Digestion and in Human Volunteers.
    Nutrients, 2022, Aug-31, Volume: 14, Issue:17

    Topics: Arginine; Creatine; Digestion; Glycation End Products, Advanced; Healthy Volunteers; Humans; Lysine; Magnesium Oxide; Pyruvaldehyde; Tandem Mass Spectrometry

2022
Crowding modulates the glycation of plasma proteins: In vitro analysis of structural modifications to albumin and transferrin and identification of sites of modification.
    Free radical biology & medicine, 2022, 11-20, Volume: 193, Issue:Pt 2

    Topics: Albumins; Arginine; Blood Proteins; Glycation End Products, Advanced; Humans; Lysine; Pyruvaldehyde; Transferrin

2022
Inhibitory effect of Ginkgo biloba seeds peptides on methylglyoxal-induced glycations.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2023, Volume: 172

    Topics: Arginine; Aspartic Acid; Ginkgo biloba; Glycation End Products, Advanced; Lysine; Maillard Reaction; Peptides; Proline; Pyruvaldehyde; Serum Albumin, Bovine; Valine

2023
Methylglyoxal-Modified Albumin Effects on Endothelial Arginase Enzyme and Vascular Function.
    Cells, 2023, 03-03, Volume: 12, Issue:5

    Topics: Acetylcholine; Albumins; Animals; Arginase; Arginine; Diabetes Mellitus; Endothelial Cells; Endothelium, Vascular; Glycation End Products, Advanced; Mice; p38 Mitogen-Activated Protein Kinases; Pyruvaldehyde

2023
Quantitation of α-Dicarbonyls, Lysine- and Arginine-Derived Advanced Glycation End Products, in Commercial Canned Meat and Seafood Products.
    Journal of agricultural and food chemistry, 2023, May-03, Volume: 71, Issue:17

    Topics: Arginine; Glycation End Products, Advanced; Glyoxal; Lysine; Meat; Pyruvaldehyde; Seafood

2023
LC-MS/MS Analysis of Reaction Products of Arginine/Methylarginines with Methylglyoxal/Glyoxal.
    Chemical research in toxicology, 2023, Nov-20, Volume: 36, Issue:11

    Topics: Arginine; Chromatography, Liquid; Glycation End Products, Advanced; Glyoxal; Magnesium Oxide; Pyruvaldehyde; Tandem Mass Spectrometry

2023