arginine and podophyllotoxin

arginine has been researched along with podophyllotoxin in 263 studies

Research

Studies (263)

TimeframeStudies, this research(%)All Research%
pre-1990224 (85.17)18.7374
1990's28 (10.65)18.2507
2000's7 (2.66)29.6817
2010's4 (1.52)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Grieder, A; Maurer, R; Stähelin, H1
Gangji, D; Hildebrand, J; Machin, D; Nouwynck, C1
Basugi, N; Nomura, K; Sano, K; Shitara, N; Takakura, K; Yamamoto, H1
El-Morsi, B; El-Sebai, IT; Gad-el-Mawla, NM; Hamza, MR; Khafagy, M; Mansour, MA; Muggia, FM; Sherif, M1
Poschmann, G; Stähelin, H1
De Pauw, M; Denis, L; Lachand, A; Pavone-Macaluso, M; Robinson, M; Schulman, C; Smith, P; Staquet, M; Sylvester, R1
García-Cañero, R; Gosalvez, M; Reinhold, H1
Buge, A; Huguenin, P; M'orin, P; Mathé, G; Palangie, T; Parrot, R; Poisson, M; Pouillart, P1
Baker, LH; Fraile, RJ; Samson, MK; Talley, RW1
Bunn, PA; Ihde, DC; Radice, PA1
Hassoun, J; Paillas, JE; Pellet, W; Peragut, JC; Prince, MA1
Sano, K; Shitara, N; Takakura, K; Yamamoto, H1
Henney, JE; Muggia, FM; Rozencweig, M; Von Hoff, DD1
Charron, D; Dumonchel, P; Jorry, F; Laurens, A; Martola, R; Thevenot, J1
Jankowski, RP; Vahrson, H1
Gautier, H; Huguenin, P; Lheritier, J; Mathé, G; Morin, P; Palangie, T; Parrot, R; Poisson, M; Pouillart, P1
Bellet, RE; Berd, D; Catalno, RB; Koons, LS; Mastrangelo, MJ1
Buge, A; Poisson, M; Pouillart, P1
Herson, J; Ragab, A; Sexhauer, C; Starling, KA; Sullivan, MP; van Eys, J1
Begg, CB; Bennett, JM; Brodovsky, HS; Carbone, PP; Chiuten, DF; Creech, RH; Falkson, G; Glick, J; Muggia, FM1
Bleyer, WA; Chard, RL; Hammond, D; Krivit, W1
Crooke, ST; Gutierrez, ML1
Baker, LH; Fraile, RJ; Hire, EA; Samson, MK1
Foley, JF; Kessinger, A; Lemon, HM1
Markwalder, H; Seiler, RW; Vassella, F1
Bataini, JP; Mashaly, R; Metzger, J; Pertuiset, BF; Poisson, M; Pouillart, P1
Bataini, JP; Hauw, JJ; Mashaly, R; Metzger, J; Pertuiset, BF; Poisson, M; Pouillart, P1
Cappelli-Gotzos, B; Despond, JM; Gotzos, V1
Garcia-Giralt, E; Jouve, M; Magdelenat, H; Palangie, T; Pouillart, P1
Osswald, H1
Avery, T; Green, A; Hayes, A; Pratt, C; Rivera, G1
Gutin, PH; Walker, MD1
Allen, LM1
Baron, A; Blic, V; Garcia-Giralt, E; Gautier, H; Huguenin, P; Jouve, M; Langlois, A; Morin, P; Palangie, T; Pouillart, P; Regensberg, C1
Brewer, CF; Gensler, WJ; Horwitz, SB; Loike, JD; Sternlicht, H1
Coulter, D; Kalish, R; Valeriote, FA; Vietti, TJ1
de Tribolet, N; Wagenknecht, L; Zander, E1
Allen, L1
Aimard, G; Chassard, JL; Devic, M; Tommasi, M; Trouillas, P1
Albahary, C; Amiel, JL; Belpomme, D; de Vassal, F; Depierre, R; Hayat, M; Jasmin, C; Mathé, G; Misset, JL; Musset, M; Pouillart, P; Schwarzenberg, L1
D'Estienne d'Orves, JF; Paillas, JE; Pellet, W; Pollet, JF1
Buge, A; Gautier, H; Huguenin, P; Lheritier, J; Mathé, G; Morin, P; Parrot, R; Poisson, M; Pouillart, P; Thy, HT1
Caramia, G; Messana, V; Pavone-Macaluso, M; Rizzo, FP1
Kenis, Y; Rozencweig, M; Schulman, CC; Staquet, M; Sylvester, R1
Hacker, M; Roberts, D1
Mechl, Z; Rovný, F; Sopková, B1
Barouh, M; Carpentier, Y; Cattan, A; Cattan, E; Pourny, C1
Stähelin, H1
Gauthier, H; Huguenin, P; Lheritier, J; Mathe, G; Morin, P; Parrot, R; Poisson, M; Pouillart, P; Thy, TH1
Donaldson, MH; Rosenstock, JG1
Bodrogi, I; Döbrentey, E; Eckhardt, S1
Allen, LM; Creaven, PJ1
Avery, T; Rivera, G; Roberts, DW1
Amiel, JL; Mathé, G; Misset, JL; Oldham, R; Pouillart, P; Schwarzenberg, L; Weiner, R1
Derry, WB; Gupta, RS; Pamidi, CC1
Behm, FG; Evans, WE; Hancock, ML; Head, DR; Mahmoud, MH; Pui, CH; Raimondi, SC; Ribeiro, RC; Rivera, GK; Sandlund, JT1
Stähelin, HF; von Wartburg, A1
Bugat, R; Canal, P; Chatelut, E; Chevreau, C; de Forni, M; Houin, G; Johnson, NP; Plusquellec, Y; Roche, H1
Gupta, R1
Schaack, J; Schedl, P; Shenk, T1
Schaak, J; Schedl, P; Shenk, T1
Dunaway, M1
Preston, GM; White, BA1
Beck, WT; Danks, MK; Fernandes, DJ1
Kiue, A; Kohno, K; Kuwano, M; Matsuo, K; Sato, S; Takano, H1
Björkholm, M1
Einstein, AB; Fleming, TR; Laufman, L; Macdonald, JS; Natale, RB; Oishi, N; Ungerleider, JS; Von Hoff, DD1
Evans, WE; Kavanagh, RL; Ochs, J; Rivera, GK; Rodman, JH; Sunderland, M; Yalowich, J1
D'Incalci, M; Figoli, F; Montaldo, PG; Sorio, R; Tirelli, U; Zanette, ML; Zucchetti, M1
Huang, L; White, JC; Wright, SE1
Carbone, A; Monfardini, S; Sorio, R; Tirelli, U; Zagonel, V1
Boas, J; Dombernowsky, P; Engelholm, SA; Hansen, OP; Rasmussen, D1
Bundy, BN; Given, FT; Muss, HB; Stehman, FB1
Bertelsen, K; Cold, S; Panduro, J; Pfeiffer, P; Rose, C; Sandberg, E1
Hines, LH; White, JC; Wright, SE1
Bogdahn, U; Dünisch, G; Löbering, HG; Martin, R; Mertens, HG; Weber, H; Zapf, J1
Carstensen, H; Hertz, H; Nolte, H2
Beerman, TA; Sigmund, RD; Woynarowski, JM2
Chen, AY; Hwang, JL; Juan, CC; Shyy, SH; Whang-Peng, J1
Foglesong, PD; Parganas, E; Roberts, DW; Wiggins, L1
Beck, WT; Danks, MK; Schmidt, CA; Wolverton, JS1
Hsiang, YH; Liu, LF1
Cellerino, R; Di Furia, L; Gramazio, A; Guidi, F; Menichetti, E; Tummarello, D1
Beerman, TA; Cullinan, EB1
Lönn, S; Lönn, U; Nylen, U; Winblad, G1
Beck, WT; Danks, MK; Deneka, DA; Schmidt, CA1
Ellis, AL; Gewirtz, DA; Povirk, LF; Randolph, JK; Swerdlow, PS; Yalowich, JC; Yanovich, S1
Martin, J; Nunn, AJ; Siddall, SJ1
Kinouchi, T; Kotake, T; Kuroda, M; Maeda, O; Miki, T; Saiki, S; Tomooka, Y; Usami, M; Yoshimura, K1
Bult, A; Holthuis, JJ; van Bennekom, WP; van der Horst, FA; van Opstal, MA1
Bugat, R; Canal, P; Chatelut, E; Chevreau, C; De Forni, M; Houin, G1
Bugat, R; Canal, P; Carton, M; Chatelut, E; Houin, G; Pinel, MC; Plusquellec, Y1
Bugat, R; Canal, P; Chatelut, E; De Biasi, J; Houin, G; Plusquellec, Y1
White, JC; Wright, SE3
McVie, G; Muggia, FM1
Bodley, AL; Kupfer, G; Liu, LF1
Boyce, RA; Hertzberg, RP; Mattern, MR; Schein, PS; Tan, KB1
D'Incalci, M; Figoli, F; Lestuzzi, C; Monfardini, S; Sorio, R; Tirelli, U; Urso, R; Zanette, ML1
Bonardi, GM; Calciati, A; Donadio, M; Giaccone, G; Testore, F1
Bonardi, G; Calciati, A; Donadio, M; Giaccone, G; Testore, F1
Chow, KC; Macdonald, TL; Ross, WE1
Richter, A; Strausfeld, U1
Brunner, KW; Cerny, T; Joss, RA; Pedrazzini, A1
Berendsen, HH; Haaxma-Reiche, H; Postmus, PE1
Jacobson-Kram, D; Lim, M; Liu, LF; Williams, JR1
Elinder, G; Finkel, Y; Henter, JI; Söder, O1
Beck, WT; Cirtain, MC; Danks, MK; Felsted, RL; Safa, AR; Suttle, DP; Trent, JM; Wolverton, JS1
Liu, LF; Rowe, TC; Yang, L1
Haim, N; Nemec, J; Roman, J; Sinha, BK1
Bork, E; Dombernowsky, P; Hansen, HH; Hansen, M; Hansen, SW; Pedersen, AG1
Brattain, MG; Long, BH; Musial, ST3
Eguchi, K; Morinaga, S; Saijo, N; Sakurai, M; Sano, T; Sasaki, Y; Shinkai, T; Suga, J; Tamura, T1
Bagatella, M; Bonardi, G; Calciati, A; Ciuffreda, L; Donadio, M; Ferrati, P; Giaccone, G1
Knippers, R; Richter, A; Strausfeld, U1
Bezwoda, WR; Derman, DP; Kew, M; Weaving, A1
Kerrigan, D; Kohn, KW; Pommier, Y1
Holthuis, JJ1
Dombernowsky, P; Hansen, HH1
D'Incalci, M; Garattini, S2
Bugat, R; Canal, P; Douste-Blazy, L; Hamza, M; Soula, G1
Bakkenist, TR; de Vries, J; Lankelma, J; Pinedo, HM; Retèl, J; van den Akker, E; Van Maanen, JM1
Bezanilla Regato, JL; Moya Calderón, E; Navajas Gutiérrez, A; Piñán, MA1
Rivera, GK1
Grem, JL; Hoth, DF; King, SA; Leyland-Jones, B; Ungerleider, RS; Wittes, RE1
Clark, PI; Slevin, ML1
Bromke, A; Bryant, DW; Gupta, R; Gupta, RS; McCalla, DR; Singh, B1
Carpenter, JT; Cox, EB; Raney, M; Vogel, CL1
Aso, Y; Fukushima, M; Matsuura, O; Naide, Y; Ohshima, S; Ono, Y; Ota, K; Suzuki, K; Tajima, A; Ushiyama, T1
Chenchaiah, PC; Gupta, R; Gupta, RS1
Chenchaiah, PC; Gupta, RS1
Beck, WT; Danks, MK; Yalowich, JC1
Forman, SJ; Levitt, LJ; Linker, CA; O'Donnell, M; Ries, CA1
Büchner, T; Ganser, A; Heil, G; Heimpel, H; Hoelzer, D; Koch, P; Kurrle, E; Lipp, T; Löffler, H; Thiel, E1
Culbert, SJ; Frankel, LS; Shimizu, H1
Fortner, CL; King, SA; Leyland-Jones, B; O'Dwyer, PJ1
Bundy, BN; DiSaia, PJ; Muss, H; Twiggs, LB1
Blume, KG; Forman, SJ; Krance, RA1
Elinder, G; Finkel, Y; Henter, JI; Holmström, S; Karlén, J; Sahlgren, B; Söder, O1
Ashmun, R; Lee, T; Parganas, E; Roberts, D; Wiggins, L; Yalowich, J1
de Vries, LG; Holthuis, JJ; Hulshoff, A; Mulder, NH; Postmus, PE; Sleijfer, DT; van Oort, WW; Verleun, H1
Abromowitch, M; Evans, WE; Hayes, FA; Rivera, GK; Rodman, JH; Sinkule, JA1
Candiloro, V; Flandina, C; Gagliano, M; Gebbia, N; Leto, G; Rausa, L; Sanguedolce, R; Tumminello, FM1
Bundy, BN; Muss, HB; Yazigi, R; Yordan, E1
Carstensen, H; Hertz, H; Jensen, T; Nolte, H1
Carbone, A; Galligioni, E; Grigoletto, E; Roncadin, M; Tirelli, U; Tumolo, S; Veronesi, A; Zagonel, V1
Canetta, R; Carbone, A; Tirelli, U; Veronesi, A; Zagonel, V1
Kooiman, A; Neijt, JP; ten Bokkel Huinink, WW; van der Burg, ME; van Oosterom, AT; van Putten, WL; Vermorken, JB; Vriesendorp, R1
Berenberg, J; Blumenstein, BA; Bukowski, RM; Johnson, K; O'Bryan, RM; Oishi, N; Quagliana, J; Rivkin, SE; Saiers, JH; Stephens, RL1
Amato, G; Broggini, M; Colombo, T; D'Incalci, M; Erba, E; Vaghi, M1
Bugat, R; Canal, P; Carton, M; Michel, C; Soula, G1
de Vries, EG; Mulder, NH; Postmus, PE; Sleijfer, DT; Vriesendorp, R; Willemse, PH1
Hiraoka, M; Nakanomyo, H; Shiraya, M1
Berg, D; Bugat, R; Canal, P; Roche, H; Rokoszak, B; Soula, G1
Christensen, IJ; Hansen, HH; Roed, H; Spang-Thomsen, M; Vindelov, LL1
Brock, KH; DeMarini, DM; Doerr, CL; Moore, MM1
Abromowitch, M; Dahl, GV; Kalwinsky, DK; Look, AT; Mirro, J; Murphy, SB; Ochs, J; Pui, CH; Rivera, G1
Abromowitch, M; Green, AA; Hayes, FA1
Brema, F; Carbone, A; Grigoletto, E; Tirelli, U; Veronesi, A; Volpe, R; Zagonei, V1
Bitran, J; Gordon, L; Johnson, C; Khandekar, JD; Krauss, S; Lanzotti, V; Locker, GY; Shaw, J; Sweet, D1
D'Incalci, M; Farina, P; Mangioni, C; Rossi, C; Sessa, C; Urso, R; Zucchetti, M1
Hines, LH; Rathmell, JP; White, JC1
Bugat, R; Canal, P; Combes, PF; Michel, C; Roche, H; Soula, G1
Hill, BT; Pritchard, J; Whelan, R1
Gewirtz, DA1
Bodey, GP; Brown, NS; Ho, DH; Issell, BF; Kanellopoulos, KS1
Kinouchi, T; Kiyohara, H; Kotake, T; Kuroda, M; Miki, T; Oda, H; Saiki, S; Usami, M1
Chen, GL; Halligan, BD; Liu, LF; Rowe, TC; Tewey, KM; Yang, L1
Glisson, B; Liu, L; Ross, W; Rowe, T; Yalowich, J1
Bork, E; Dombernowsky, P; Hansen, HH; Osterlind, K; Pedersen, AG1
Baumelou, A; Habibi, B; Seradaru, M1
Rysánková, J; Uchytil, B1
Funnell, CF; Hope, DM; Humphrey, DC; Lowenthal, RM; Stewart, IG1
Fry, DW; Goldman, ID; Yalowich, JC1
Crom, WR; Evans, WE; Hutson, PR; Sinkule, JA; Stewart, CF; Yee, GC1
Markwalder, H; Seiler, RW; Zimmermann, A1
Di Stefano, E; Gerosa, MA; Olivi, A1
Calciati, A; Conte, PF; Giaccone, G; Musella, R1
Barrere, M; Bes, A; Fanjaud, G; Geraud, G; Larrue, V1
Long, BH; Minocha, A1
Płuzańska, A; Robak, T1
Campbell, AM; Ekert, H; Waters, KD1
Carbone, A; Crivellari, D; Franchin, G; Galligioni, E; Grigoletto, E; Tirelli, U; Trovò, M; Tumolo, S; Veronesi, A; Volpe, R1
Alonso, MT; Leyland-Jones, B; Marsoni, S; O'Dwyer, PJ1
Gasalla Chacón, R; Gónzalez Larriba, JL; Grande, C; Montero García, JM; Picaporte, MA1
D'Incalci, M; Mangioni, C; Rossi, C; Sessa, C; Urso, R; Zucchetti, M1
Crivellari, D; Franchin, G; Galligioni, E; Grigoletto, E; Talamini, R; Tirelli, U; Trovó, MG; Tumolo, S; Veronesi, A1
Dennery, J; Hopkins, HS; Hugenholtz, H; Montpetit, V; Nundy, D; Prior, J; Richard, MT; Stewart, DJ1
Bellamy, AS; Hill, BT1
Dow, LW; Evans, WE; Horvath, A; Look, AT; Sinkule, JA1
Crom, WR; Dahl, GV; Evans, WE; Melton, ET; Sinkule, JA; Stewart, CF1
Gupta, RS; Singh, B1
Carreras, E; Grañena, A; Marín, P; Olivé, MT; Rozman, C; Sierra, J1
Rafecas, FJ; Sanz, MA1
Brinkman, UA; de Ruiter, C; de Vries, J; Frei, RW; Werkhoven-Goewie, CE1
Alberts, DS; Dorr, RT1
Evans, WE; Sinkule, JA1
Lee, T; Roberts, D2
Colombo, N; D'Incalci, M; Landoni, F; Mangioni, C; Sessa, C1
Canetta, R; D'Incalci, M; Franchin, G; Galligioni, E; Grigoletto, E; Rossi, C; Tirelli, U; Trovò, MG; Tumolo, S; Veronesi, A1
Dalesio, O; de Pauw, M; Denis, L; Robinson, M; Schulman, CC; Smith, P; Sylvester, R; Viggiano, G1
Anderson, J; Bennett, JM; Berard, CW; Brodovsky, HS; Glick, JH; Merrill, JM; Neiman, RS; O'Connell, MJ1
Fuerst, ML1
Gupta, RS1
Broggini, M; Colombo, T; D'Incalci, M1
Aur, RJ; Avery, TL; Bowman, WP; Dahl, GV; Rivera, G; Wood, A1
Carbone, A; Franchin, G; Galligioni, E; Grigoletto, E; Tirelli, U; Trovo, MG; Tumolo, S; Veronesi, A; Volpe, R1
Razon-Veronesi, S1
De Bruyne, GK; Dragonetti, CH; Mareel, MM; Van Cauwenberge, RM1
Aur, RJ; Avery, TL; Bowman, WP; Dahl, GV; Kalwinsky, DK; Murphy, SB; Rivera, G; Stagner, S; Wood, A1
Dombernowsky, P; Hansen, HH; Nissen, NI; Pedersen, AG1
Kondrat'eva, NA; Maiakova, SA; Makhonova, LA; Vialushkin, BIa1
Gershanovich, ML; Kondrat'ev, VB; Kondrat'eva, NA; Lebedev, VN; Vialushkin, VIa1
Straus, DJ; Warrell, RP; Young, CW1
Loike, JD1
Creaven, PJ1
Issell, BF1
Macbeth, FR1
Bedogni, P; Canetta, R; Florentine, S; Hilgard, P; Lenaz, L1
Elson, P; Khandekar, JD; Qazi, R1
Baumelou, A; Habibi, B; Lopez, M; Marteau, R; Salmon, C; Serdaru, M; Vonlanthen, M1
Curry, ME; Issell, BF; Tihon, C1
Crom, WR; Dow, L; Evans, WE; Look, AT; Rivera, G; Sinkule, JA1
Allen, LM; Nordqvist, S; Okonmah, AD; Tejada, F1
Aur, RJ; Avery, TL; Bowman, WP; Dahl, GV; Murphy, SB; Rivera, G; Simone, JV1
Casper, J; Cornet, J; Evans, WE; Green, AA; Hayes, FA1
Abbou, C; Auvert, J; Botto, H; Garcia-Giralt, E; Hannoun, M; Jouve, M; Lachand, AT; Morin, P; Palangie, T; Pouillart, P1
Colvin, M; Jardine, I; Strife, RJ2
Gershanovich, ML; Kondrat'ev, VB; Kondrat'eva, NA; Lebedev, VN; Vygovskaia, IaI1
Carbone, A; Galligioni, E; Grigoletto, E; Tirelli, U; Trovò, MG; Tumolo, S; Veronesi, A1
Aur, RJ; Avery, TL; Dahl, GV; Pratt, CB; Rivera, G; Wood, A1
Schulz, JJ; Speckhart, VJ; Spremulli, E; Wampler, GL1
Seiler, RW1
Hacker, M; Jackson, CW; Roberts, D1
Hilliard, S; Peck, C; Roberts, D1
Bastion, Y; Brice, P; Coiffier, B; Espinouse, D; Gisselbrecht, C; Haioun, C; Marolleau, JP; Reyes, F; Salles, G; Sonet, A1
Chatterjee, R; Goldstone, AH; Katz, M; McGarrigle, HH; Mills, W1
Gemba, K; Kiura, K; Matsumura, T; Moritaka, T; Ohnoshi, T; Segawa, Y; Shibayama, T; Tabata, M; Takigawa, N; Ueoka, H1
Campling, BG; Jain, N; Lam, YM; Pym, J1
Imbert, TF1
Coffman, FD; Cohen, S; Fresa, KL; Hingley, ST; Mody, NS; Ye, X1
Amylon, M; Barredo, JC; Borowitz, M; Camitta, BM; Kurtzberg, J; Laver, JH; Link, MP; Murphy, SB; Pullen, J; Ravindranath, Y; Schwenn, M; Shuster, J1
Castro, MA; del Corral, JM; Feliciano, AS; Gordaliza, M1
Bunn, PA; Simon, GR1
Castro, MA; del Corral, JM; García, PA; Gómez-Zurita, MA; Gordaliza, M1
Seiter, K1
Lv, M; Tian, X; Xu, H1
Lv, M; Xu, H1
Hu, Y; Liao, JX; Liu, H; Sun, JS; Tu, YH1
Jakobs, A; Klempnauer, KH; Yusenko, M1

Reviews

25 review(s) available for arginine and podophyllotoxin

ArticleYear
VM 26 and VP 16-213: a comparative analysis.
    Cancer, 1977, Volume: 40, Issue:1

    Topics: Animals; Brain Neoplasms; Drug Evaluation; Etoposide; Humans; Kinetics; Leukemia; Lung Neoplasms; Lymphoma; Neoplasms, Experimental; Podophyllotoxin; Teniposide; Urinary Bladder Neoplasms

1977
Pediatric cancer chemotherapy: an updated review. I. Cis-Diammine--dichloroplatinum II (cisplatin), VM-26 (teniposide), VP-16 (etoposide), mitomycin C.
    Cancer treatment reviews, 1979, Volume: 6, Issue:3

    Topics: Child; Cisplatin; Clinical Trials as Topic; Drug Administration Schedule; Etoposide; Humans; Leukemia; Mitomycins; Neoplasms; Podophyllotoxin; Teniposide

1979
The chemical and biological route from podophyllotoxin glucoside to etoposide: ninth Cain memorial Award lecture.
    Cancer research, 1991, Jan-01, Volume: 51, Issue:1

    Topics: Aldehydes; Antineoplastic Agents; Cell Division; Cyclosporins; Etoposide; Glucosides; Growth Inhibitors; History, 19th Century; History, 20th Century; Plants, Medicinal; Plants, Toxic; Podophyllotoxin; Podophyllum; Structure-Activity Relationship; Teniposide

1991
Etoposide and teniposide in the treatment of acute leukemia.
    Medical oncology and tumor pharmacotherapy, 1990, Volume: 7, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Etoposide; Humans; Leukemia, Myeloid, Acute; Podophyllotoxin; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Teniposide

1990
A phase II study with teniposide (VM26) in patients with progressed or relapsed small cell lung cancer (SCLC).
    Journal of chemotherapy (Florence, Italy), 1989, Volume: 1, Issue:1

    Topics: Adult; Aged; Carcinoma, Small Cell; Drug Evaluation; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin; Retrospective Studies; Teniposide

1989
Etoposide and teniposide. Bioanalysis, metabolism and clinical pharmacokinetics.
    Pharmaceutisch weekblad. Scientific edition, 1988, Jun-17, Volume: 10, Issue:3

    Topics: Etoposide; Humans; Podophyllotoxin; Teniposide

1988
The epipodophyllotoxin derivatives VM26 and VP16: experimental and clinical aspects.
    European journal of haematology. Supplementum, 1988, Volume: 48

    Topics: Animals; Antineoplastic Agents; Etoposide; Humans; Podophyllotoxin; Teniposide

1988
Podophyllotoxin derivatives VP-16 and VM-26.
    Cancer chemotherapy and biological response modifiers, 1988, Volume: 10

    Topics: Animals; Drug Resistance; Etoposide; Humans; Molecular Structure; Podophyllotoxin; Teniposide

1988
Podophyllotoxin derivatives VP-16 and VM-26.
    Cancer chemotherapy and biological response modifiers, 1987, Volume: 9

    Topics: Animals; Cell Survival; Drug Interactions; Drug Resistance; Etoposide; Humans; Podophyllotoxin; Teniposide

1987
Teniposide in the treatment of leukemia: a case study of conflicting priorities in the development of drugs for fatal diseases.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1988, Volume: 6, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Drug Administration Schedule; Humans; Leukemia, Lymphoid; Podophyllotoxin; Teniposide

1988
The clinical pharmacology of etoposide and teniposide.
    Clinical pharmacokinetics, 1987, Volume: 12, Issue:4

    Topics: Chemical Phenomena; Chemistry; Drug Stability; Etoposide; Humans; Kidney; Kinetics; Liver; Podophyllotoxin; Teniposide

1987
Pharmacokinetics of anticancer drugs in children.
    Drug metabolism reviews, 1983, Volume: 14, Issue:5

    Topics: Aminoacridines; Amsacrine; Antibiotics, Antineoplastic; Antineoplastic Agents; Bleomycin; Child; Cyclophosphamide; Etoposide; Humans; Kinetics; Mercaptopurine; Methotrexate; Naphthacenes; Podophyllotoxin; Teniposide; Vinca Alkaloids

1983
Teniposide: a review of 12 years of experience.
    Cancer treatment reports, 1984, Volume: 68, Issue:12

    Topics: Adult; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Cycle; Cell Line; Child; Clinical Trials as Topic; Colonic Neoplasms; DNA, Neoplasm; Drug Evaluation, Preclinical; Drug Resistance; Humans; Leukemia; Lymphoma; Mice; Neoplasms; Neoplasms, Experimental; Neuroblastoma; Podophyllotoxin; Teniposide

1984
The epipodophyllotoxin derivatives VM-26 and VP-16-213, 1976-1979, a review.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1980, Volume: 74

    Topics: Animals; Antineoplastic Agents; Etoposide; Hodgkin Disease; Humans; Leukemia, Lymphoid; Lung Neoplasms; Podophyllotoxin; Teniposide

1980
VP16-213 and podophyllotoxin. A study on the relationship between chemical structure and biological activity.
    Cancer chemotherapy and pharmacology, 1982, Volume: 7, Issue:2-3

    Topics: Animals; Chemical Phenomena; Chemistry; DNA; Etoposide; HeLa Cells; Humans; Microtubules; Molecular Conformation; Nucleosides; Podophyllotoxin; Structure-Activity Relationship; Teniposide

1982
The clinical pharmacology of VM26 and VP16-213. A brief overview.
    Cancer chemotherapy and pharmacology, 1982, Volume: 7, Issue:2-3

    Topics: Biotransformation; Blood-Brain Barrier; Etoposide; Humans; Intestinal Absorption; Kinetics; Models, Biological; Podophyllotoxin; Teniposide; Tissue Distribution

1982
The podophyllotoxin derivatives VP16-213 and VM26.
    Cancer chemotherapy and pharmacology, 1982, Volume: 7, Issue:2-3

    Topics: Animals; Chemical Phenomena; Chemistry; Drug Therapy, Combination; Etoposide; Humans; Neoplasms; Podophyllotoxin; Teniposide

1982
VM26: phase I and II studies.
    Cancer chemotherapy and pharmacology, 1982, Volume: 7, Issue:2-3

    Topics: Drug Evaluation; Humans; Neoplasms; Podophyllotoxin; Teniposide

1982
Current development of podophyllotoxins.
    Cancer chemotherapy and pharmacology, 1982, Volume: 7, Issue:2-3

    Topics: Chemistry, Pharmaceutical; Drug Compounding; Drug Stability; Drug Synergism; Drug Therapy, Combination; Etoposide; Humans; Kinetics; Podophyllotoxin; Teniposide

1982
Antitumor properties of podophyllotoxin and related compounds.
    Current pharmaceutical design, 2000, Volume: 6, Issue:18

    Topics: Antineoplastic Agents, Phytogenic; Antiviral Agents; Etoposide; Humans; Immunosuppressive Agents; Podophyllotoxin; Structure-Activity Relationship; Teniposide

2000
Taxanes in the treatment of advanced (stage III and IV) non-small cell lung cancer (NSCLC): recent developments.
    Cancer investigation, 2003, Volume: 21, Issue:1

    Topics: Angiogenesis Inhibitors; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Clinical Trials as Topic; Combined Modality Therapy; Deoxycytidine; Docetaxel; Etoposide; Female; Gemcitabine; Humans; Lung Neoplasms; Male; Microtubules; Multicenter Studies as Topic; Neoadjuvant Therapy; Organoplatinum Compounds; Paclitaxel; Palliative Care; Podophyllotoxin; Randomized Controlled Trials as Topic; Salvage Therapy; Survival Analysis; Taxoids; Teniposide; Treatment Outcome; Vinblastine; Vinorelbine

2003
Podophyllotoxin: distribution, sources, applications and new cytotoxic derivatives.
    Toxicon : official journal of the International Society on Toxinology, 2004, Sep-15, Volume: 44, Issue:4

    Topics: Cytotoxins; Etoposide; Lignans; Organophosphorus Compounds; Plants, Toxic; Podophyllotoxin; Teniposide; Tumor Cells, Cultured

2004
Toxicity of the topoisomerase II inhibitors.
    Expert opinion on drug safety, 2005, Volume: 4, Issue:2

    Topics: Antineoplastic Agents; Cardiovascular Diseases; Daunorubicin; Doxorubicin; Enzyme Inhibitors; Epirubicin; Etoposide; Humans; Idarubicin; Leukemia; Middle Aged; Mitoxantrone; Mucositis; Podophyllotoxin; Teniposide; Topoisomerase II Inhibitors; Vascular Diseases

2005
A review on hemisynthesis, biosynthesis, biological activities, mode of action, and structure-activity relationship of podophyllotoxins: 2003-2007.
    Current medicinal chemistry, 2009, Volume: 16, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Etoposide; Humans; Inhibitory Concentration 50; Organophosphorus Compounds; Podophyllotoxin; Structure-Activity Relationship; Teniposide

2009
Recent advances in semisynthesis, biosynthesis, biological activities, mode of action, and structure-activity relationship of podophyllotoxins: an update (2008-2010).
    Mini reviews in medicinal chemistry, 2011, Volume: 11, Issue:10

    Topics: Antineoplastic Agents, Phytogenic; Cell Survival; Drug Screening Assays, Antitumor; Etoposide; Humans; Organophosphorus Compounds; Podophyllotoxin; Structure-Activity Relationship; Teniposide

2011

Trials

39 trial(s) available for arginine and podophyllotoxin

ArticleYear
Enhancement of bone marrow toxicity of VM-26-CCNU combination by bleomycin.
    Cancer treatment reports, 1977, Volume: 61, Issue:9

    Topics: Adult; Aged; Bleomycin; Bone Marrow; Brain Neoplasms; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Leukopenia; Lomustine; Male; Middle Aged; Nitrosourea Compounds; Podophyllotoxin; Teniposide

1977
Chemotherapeutic management of carcinoma of the bilharzial bladder: a phase II trial with hexamethylmelamine and VM-26.
    Cancer treatment reports, 1978, Volume: 62, Issue:7

    Topics: Adolescent; Adult; Aged; Altretamine; Carcinoma; Carcinoma, Squamous Cell; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Male; Middle Aged; Podophyllotoxin; Schistosomiasis; Teniposide; Triazines; Urinary Bladder Diseases; Urinary Bladder Neoplasms

1978
Adjuvant therapy of T1 bladder carcinoma: preliminary results of an EORTC randomized study.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1978, Volume: 68

    Topics: Humans; Neoplasm Recurrence, Local; Neoplasm Staging; Pathology; Podophyllotoxin; Random Allocation; Teniposide; Thiotepa; Urinary Bladder Neoplasms

1978
Therapeutic trials with VP-16-213 and VM-26: active agents in small cell lung cancer, non-Hodgkin's lymphomas, and other malignancies.
    Cancer treatment reports, 1979, Volume: 63, Issue:8

    Topics: Alopecia; Carcinoma, Small Cell; Clinical Trials as Topic; Drug Evaluation; Etoposide; Humans; Leukemia; Leukopenia; Lung Neoplasms; Lymphoma; Podophyllotoxin; Teniposide

1979
[The toxicity of massive dosis of VM26 (4-demethyl-epipodophyllotoxin-beta-D-thenylidene glucoside). A contribution to the therapy of advanced ovarian cancer (author's transl)].
    Medizinische Klinik, 1977, Dec-09, Volume: 72, Issue:49

    Topics: Aged; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Leukopenia; Middle Aged; Nausea; Ovarian Neoplasms; Podophyllotoxin; Remission, Spontaneous; Teniposide; Vomiting

1977
Treatment of malignant gliomas and brain metastases in adults using a combination of adriamycine, VM 26, and CCNU. Results of a type II trial.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1977, Issue:62

    Topics: Adult; Aged; Brain Neoplasms; Breast Neoplasms; Clinical Trials as Topic; Doxorubicin; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Glioma; Humans; Lomustine; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Nitrosourea Compounds; Podophyllotoxin; Teniposide

1977
Phase II trial of VM-26 in patients with metastatic malignant melanoma.
    Cancer treatment reports, 1978, Volume: 62, Issue:3

    Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Podophyllotoxin; Teniposide

1978
[A study of the use of sequential chemotherapy in 176 cases of glioblastoma (author's transl)].
    Revue neurologique, 1978, Volume: 134, Issue:5

    Topics: Adult; Brain Neoplasms; Clinical Trials as Topic; Doxorubicin; Drug Therapy, Combination; Follow-Up Studies; Glioma; Humans; Lomustine; Nitrosourea Compounds; Podophyllotoxin; Procarbazine; Random Allocation; Remission, Spontaneous; Teniposide; Time Factors

1978
Nonresponsiveness of brain tumors to VM-26 therapy in children.
    Cancer treatment reports, 1979, Volume: 63, Issue:1

    Topics: Adolescent; Brain Neoplasms; Child; Child, Preschool; Clinical Trials as Topic; Humans; Podophyllotoxin; Teniposide; Time Factors

1979
VM-26, a new anticancer drug with effectiveness in malignant lymphoma: an Eastern Cooperative Oncology Group Study (EST 1474).
    Cancer treatment reports, 1979, Volume: 63, Issue:1

    Topics: Adult; Aged; Blood Cell Count; Clinical Trials as Topic; Drug Evaluation; Female; Hodgkin Disease; Humans; Lymphoma; Male; Middle Aged; Podophyllotoxin; Teniposide

1979
Phase II study of VM-26 in acute leukemia, neuroblastoma, and other refractory childhood malignancies: a report from the Children's Cancer Study Group.
    Cancer treatment reports, 1979, Volume: 63, Issue:6

    Topics: Acute Disease; Adolescent; Adult; Bone Marrow; Child; Clinical Trials as Topic; Drug Evaluation; Humans; Leukemia; Leukemia, Lymphoid; Neoplasms; Neuroblastoma; Podophyllotoxin; Remission, Spontaneous; Teniposide

1979
Pediatric cancer chemotherapy: an updated review. I. Cis-Diammine--dichloroplatinum II (cisplatin), VM-26 (teniposide), VP-16 (etoposide), mitomycin C.
    Cancer treatment reviews, 1979, Volume: 6, Issue:3

    Topics: Child; Cisplatin; Clinical Trials as Topic; Drug Administration Schedule; Etoposide; Humans; Leukemia; Mitomycins; Neoplasms; Podophyllotoxin; Teniposide

1979
Use of VM-26 as a single agent in the treatment of renal carcinoma.
    Cancer clinical trials, 1979,Winter, Volume: 2, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Bone Marrow; Clinical Trials as Topic; Female; Humans; Hypotension; Kidney Neoplasms; Male; Middle Aged; Podophyllotoxin; Teniposide

1979
[Non resectable colonic cancer. Results from a test of chemotherapy with simultaneous prescription of VM26, methyl-CCNU and 5 fluoro-uracile (author's transl)].
    La Nouvelle presse medicale, 1978, Jun-24, Volume: 7, Issue:25

    Topics: Adult; Aged; BCG Vaccine; Colonic Neoplasms; Drug Therapy, Combination; Female; Fluorouracil; Humans; Immunotherapy; Lomustine; Male; Middle Aged; Nitrosourea Compounds; Podophyllotoxin; Teniposide

1978
[Surgically treated supratentorial gliomas in the adult. Favourable action of a podophyllin derivative (VM 26) administered alone (author's transl)].
    La Nouvelle presse medicale, 1978, Dec-09, Volume: 7, Issue:44

    Topics: Brain Neoplasms; Drug Tolerance; Glioma; Humans; Podophyllotoxin; Teniposide

1978
[Letter: Chemotherapy of operated malignant brain gliomas using a combination of VM 26 and CCNU].
    La Nouvelle presse medicale, 1976, Feb-14, Volume: 5, Issue:7

    Topics: Brain Neoplasms; Clinical Trials as Topic; Drug Therapy, Combination; Follow-Up Studies; Glioma; Humans; Lomustine; Nitrosourea Compounds; Podophyllotoxin; Teniposide

1976
[Trial treatment of glioblastomas in adults and cerebral metastais by adriamycin, VM 26 and CCNU combination. Result of a type II trial].
    La Nouvelle presse medicale, 1976, Jun-19, Volume: 5, Issue:25

    Topics: Adult; Aged; Brain Neoplasms; Clinical Trials as Topic; Doxorubicin; Drug Evaluation; Drug Therapy, Combination; Female; Glioma; Humans; Lomustine; Male; Middle Aged; Neoplasm Metastasis; Nitrosourea Compounds; Podophyllotoxin; Remission, Spontaneous; Teniposide

1976
Preliminary evaluation of VM-26: a new epipodophyllotoxin derivative, in the treatment of urogenital tumours.
    European urology, 1975, Volume: 1, Issue:1

    Topics: Adenocarcinoma; Antibiotics, Antineoplastic; Antineoplastic Agents; Carcinoma, Papillary; Chemotherapy, Cancer, Regional Perfusion; Clinical Trials as Topic; Drug Evaluation; Humans; Infusions, Parenteral; Leiomyosarcoma; Male; Mitosis; Neoplasm Metastasis; Podophyllotoxin; Prostatic Neoplasms; Teniposide; Teratoma; Testicular Neoplasms; Therapeutic Irrigation; Urinary Bladder Neoplasms

1975
EORTC randomized trial for the adjuvant therapy of T1 bladder carcinoma.
    European urology, 1976, Volume: 2, Issue:6

    Topics: Carcinoma, Papillary; Clinical Trials as Topic; Follow-Up Studies; Humans; Neoplasm Recurrence, Local; Podophyllotoxin; Postoperative Care; Remission, Spontaneous; Teniposide; Thiotepa; Urinary Bladder; Urinary Bladder Neoplasms

1976
Phase I-II trial of VM-26 (NSC-122819) in the treatment of children with late-stage leukemia.
    Cancer treatment reports, 1976, Volume: 60, Issue:3

    Topics: Acute Disease; Adolescent; Child; Child, Preschool; Drug Evaluation; Hematopoietic Stem Cells; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukocyte Count; Podophyllotoxin; Teniposide

1976
Results obtained with combination therapy of VM-26, natulan and prednisolone in generalized Hodgkin's disease.
    Chemotherapy, 1975, Volume: 21, Issue:3-4

    Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Drug Evaluation; Drug Therapy, Combination; Female; Hodgkin Disease; Humans; Male; Middle Aged; Podophyllotoxin; Prednisolone; Procarbazine; Radiography; Teniposide; Time Factors

1975
Acute myeloid leukemia in children treated with epipodophyllotoxins for acute lymphoblastic leukemia.
    The New England journal of medicine, 1991, Dec-12, Volume: 325, Issue:24

    Topics: Acute Disease; Adolescent; Child; Child, Preschool; Drug Administration Schedule; Etoposide; Humans; Leukemia, Myeloid; Neoplasms, Second Primary; Podophyllotoxin; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Risk Factors; Teniposide

1991
Teniposide and cisplatin given by intraperitoneal administration: preclinical and phase I/pharmacokinetic studies.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1991, Volume: 2, Issue:3

    Topics: Adult; Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Evaluation; Drug Synergism; Etoposide; Female; Humans; Injections, Intraperitoneal; Leukemia P388; Leukopenia; Male; Mice; Middle Aged; Peritoneal Neoplasms; Podophyllotoxin; Remission Induction; Teniposide

1991
VM-26 in colorectal carcinoma: a Southwest Oncology Group study.
    Investigational new drugs, 1990, Volume: 8, Issue:1

    Topics: Colorectal Neoplasms; Humans; Leukopenia; Multicenter Studies as Topic; Podophyllotoxin; Teniposide

1990
Pharmacokinetics of continuous infusion of methotrexate and teniposide in pediatric cancer patients.
    Cancer research, 1990, Jul-15, Volume: 50, Issue:14

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Clinical Trials as Topic; Drug Administration Schedule; Humans; Infusions, Intravenous; Leucovorin; Metabolic Clearance Rate; Methotrexate; Podophyllotoxin; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Teniposide

1990
Combination chemotherapy of hepatocellular cancer. Comparison of adriamycin + VM 26 + 5-fluorouracil with mAMSA + VM 26 + 5-fluorouracil.
    Oncology, 1987, Volume: 44, Issue:4

    Topics: Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Clinical Trials as Topic; Doxorubicin; Female; Fluorouracil; Humans; Liver Neoplasms; Male; Podophyllotoxin; Random Allocation; Teniposide; Time Factors

1987
The epipodophyllotoxin teniposide in therapy for childhood acute lymphocytic leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1988, Volume: 6, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Clinical Trials as Topic; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia, Lymphoid; Podophyllotoxin; Teniposide

1988
Teniposide in epithelial ovarian carcinoma: a phase II trial of the Gynecologic Oncology Group.
    Cancer treatment reports, 1986, Volume: 70, Issue:10

    Topics: Adult; Aged; Clinical Trials as Topic; Drug Evaluation; Female; Gastrointestinal Diseases; Hematologic Diseases; Humans; Middle Aged; Ovarian Neoplasms; Podophyllotoxin; Prognosis; Teniposide

1986
Phase II study of teniposide (VM-26) in multiple myeloma.
    American journal of clinical oncology, 1985, Volume: 8, Issue:4

    Topics: Adult; Aged; Blood Cell Count; Blood Proteins; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Immunoglobulins; Infusions, Parenteral; Leukopenia; Male; Middle Aged; Multiple Myeloma; Podophyllotoxin; Teniposide

1985
Adjuvant chemotherapy with VM 26 and CCNU after operation and radiotherapy of high-grade supratentorial astrocytomas.
    Surgical neurology, 1980, Volume: 13, Issue:1

    Topics: Adult; Aged; Brain Neoplasms; Drug Therapy, Combination; Female; Glioblastoma; Humans; Lomustine; Male; Middle Aged; Nitrosourea Compounds; Podophyllotoxin; Teniposide

1980
[New antineoplastic drugs of the podophyllotoxin derivative group].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1983, Jan-03, Volume: 38, Issue:1

    Topics: Adult; Child; Clinical Trials as Topic; Etoposide; Female; Humans; Leukemia; Lung Neoplasms; Lymphoma; Neoplasms; Ovarian Neoplasms; Podophyllotoxin; Teniposide; Urinary Bladder Neoplasms

1983
VM-26 and dimethyl triazeno imidazole carboxamide in Ewing's sarcoma.
    Australian paediatric journal, 1983, Volume: 19, Issue:1

    Topics: Adolescent; Bone Neoplasms; Child; Child, Preschool; Clinical Trials as Topic; Dacarbazine; Doxorubicin; Drug Therapy, Combination; Female; Humans; Male; Podophyllotoxin; Random Allocation; Sarcoma, Ewing; Teniposide; Vincristine

1983
Teniposide: a review of 12 years of experience.
    Cancer treatment reports, 1984, Volume: 68, Issue:12

    Topics: Adult; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Cycle; Cell Line; Child; Clinical Trials as Topic; Colonic Neoplasms; DNA, Neoplasm; Drug Evaluation, Preclinical; Drug Resistance; Humans; Leukemia; Lymphoma; Mice; Neoplasms; Neoplasms, Experimental; Neuroblastoma; Podophyllotoxin; Teniposide

1984
Prophylactic chemotherapy of superficial transitional cell bladder carcinoma: an EORTC randomized trial comparing thiotepa, an epipodophyllotoxin (VM26) and TUR alone.
    European urology, 1982, Volume: 8, Issue:4

    Topics: Carcinoma, Transitional Cell; Clinical Trials as Topic; Follow-Up Studies; Humans; Neoplasm Recurrence, Local; Podophyllotoxin; Random Allocation; Teniposide; Thiotepa; Urinary Bladder Neoplasms

1982
Comparative trial of two teniposide-based combination chemotherapy regimens for the treatment of advanced malignant lymphomas.
    Cancer treatment reports, 1982, Volume: 66, Issue:12

    Topics: Adult; Altretamine; Cisplatin; Clinical Trials as Topic; Drug Therapy, Combination; Female; Hematopoietic System; Humans; Lymphoma; Male; Middle Aged; Podophyllotoxin; Prednisone; Prospective Studies; Random Allocation; Teniposide

1982
[Results of a clinical study of an epipodophyllotoxin preparation (VM 26) in children with hemoblastoses].
    Problemy gematologii i perelivaniia krovi, 1981, Volume: 26, Issue:4

    Topics: Child; Clinical Trials as Topic; Drug Therapy, Combination; Hodgkin Disease; Humans; Leukemia, Lymphoid; Lymphoma, Non-Hodgkin; Podophyllotoxin; Prednisolone; Teniposide; Time Factors

1981
[Use of preparation VM 26 (epipodophyllotoxin) for treating lymphomas in children and adults].
    Voprosy onkologii, 1981, Volume: 27, Issue:4

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Clinical Trials as Topic; Hodgkin Disease; Humans; Infant; Lymphoma; Lymphoma, Non-Hodgkin; Middle Aged; Podophyllotoxin; Teniposide; Time Factors

1981
Combination chemotherapy for patients with relapsed malignant lymphoma using methyl-GAG and teniposide (VM-26).
    Cancer treatment reports, 1982, Volume: 66, Issue:5

    Topics: Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combination; Guanidines; Humans; Lymphoma; Mitoguazone; Podophyllotoxin; Teniposide

1982
Comparison of the use of teniposide and vincristine in combination chemotherapy for non-Hodgkin's lymphoma.
    Cancer treatment reports, 1982, Volume: 66, Issue:1

    Topics: Antineoplastic Agents; Cyclophosphamide; Drug Therapy, Combination; Hematologic Diseases; Humans; Kidney Diseases; Lymphoma; Podophyllotoxin; Prednisolone; Teniposide; Vincristine

1982

Other Studies

201 other study(ies) available for arginine and podophyllotoxin

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Comparative study of early effects of epipodophyllotoxin derivatives and other cytostatic agents on mastocytoma cultures.
    Cancer research, 1977, Volume: 37, Issue:9

    Topics: Antineoplastic Agents; Bleomycin; Cell Division; Cell Line; Colchicine; Cytarabine; DNA, Neoplasm; Etoposide; Mast-Cell Sarcoma; Mechlorethamine; Mercaptopurine; Methotrexate; Mitosis; Neoplasm Proteins; Neoplasms, Experimental; Podophyllotoxin; Razoxane; RNA, Neoplasm; Teniposide; Vincristine; X-Rays

1977
Single-drug chemotherapy of bladder cancer with adriamycin, VM-26 or bleomycin. A phase II multicentric, co-operative study.
    European urology, 1976, Volume: 2, Issue:3

    Topics: Bleomycin; Doxorubicin; Humans; Neoplasm Metastasis; Podophyllotoxin; Teniposide; Urinary Bladder Neoplasms

1976
[Role of VM26 on glioma cells in vitro--analysis of G0 cells and recruitment (author's transl)].
    Neurologia medico-chirurgica, 1978, Volume: 18, Issue:6

    Topics: Brain Neoplasms; Cells, Cultured; Glioma; Kinetics; Mitosis; Podophyllotoxin; Teniposide

1978
Effects of the epipodophyllotoxin derivative VM 26 in mitosis and in interphase.
    Oncology, 1978, Volume: 35, Issue:5

    Topics: Animals; Cell Cycle; Cell Line; Interphase; Mast-Cell Sarcoma; Mitosis; Podophyllotoxin; Sarcoma, Experimental; Teniposide

1978
Delayed pyridine nucleotide reoxidation induced by the anticancer agent VM-26 as measured in vivo and in situ by NADH microfluorimetry.
    European journal of cancer, 1975, Volume: 11, Issue:10

    Topics: Animals; Brain; Female; Fluorometry; Hypoxia; Mitochondria; NAD; Oxidation-Reduction; Oxygen Consumption; Podophyllotoxin; Rats; Rhabdomyosarcoma; Sarcoma, Experimental; Teniposide

1975
[Treatment of inoperable glioblastomas using a combination of adriamycin, VM 26 and CCNU].
    Bulletin du cancer, 1977, Volume: 64, Issue:1

    Topics: Adult; Aged; Brain Neoplasms; Doxorubicin; Drug Therapy, Combination; Drug Tolerance; Glioblastoma; Humans; Lomustine; Methods; Middle Aged; Nitrosourea Compounds; Podophyllotoxin; Teniposide

1977
VM26 (NSC-122819): a clinical study in advanced cancer of the lung and ovary.
    European journal of cancer, 1978, Volume: 14, Issue:12

    Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Female; Humans; Leukopenia; Lung Neoplasms; Male; Middle Aged; Ovarian Neoplasms; Podophyllotoxin; Remission, Spontaneous; Teniposide; Thrombocytopenia

1978
[Value of chemotherapy associated with conventional treatment of malignant gliomas of the brain. Study of 95 cases with histological verification and follow-up of 1 to 6 years 9 months].
    Revue neurologique, 1979, Volume: 135, Issue:3

    Topics: Administration, Oral; Adult; Brain Neoplasms; Carmustine; Drug Evaluation; Drug Therapy, Combination; Female; Follow-Up Studies; Glioblastoma; Glioma; Humans; Injections, Intravenous; Lomustine; Male; Middle Aged; Nitrosourea Compounds; Podophyllotoxin; Retrospective Studies; Teniposide

1979
Recruitment-chemoradiotherapy with VM 26 (epipodophyllotoxin) for induction treatment of malignant brain tumours.
    Acta neurochirurgica. Supplementum, 1979, Volume: 28, Issue:2

    Topics: Adenocarcinoma; Animals; Brain Neoplasms; Cell Line; Fibrosarcoma; Glioma; Humans; Mitosis; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Podophyllotoxin; Radiotherapy Dosage; Rats; Teniposide; Vincristine

1979
[Combination of adriamycin, VM 26, cyclophosphamide and prednisone in the treatment of hematosarcomas].
    Annales de medecine interne, 1977, Volume: 128, Issue:5

    Topics: Adolescent; Adult; Aged; Cyclophosphamide; Doxorubicin; Drug Evaluation; Drug Therapy, Combination; Female; Hodgkin Disease; Humans; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Middle Aged; Podophyllotoxin; Prednisone; Teniposide

1977
VM-26 as a second drug in the treatment of brain gliomas.
    Cancer treatment reports, 1979, Volume: 63, Issue:3

    Topics: Antineoplastic Agents; Brain Neoplasms; Drug Therapy, Combination; Female; Glioma; Humans; Nitrosourea Compounds; Podophyllotoxin; Teniposide

1979
Combination chemotherapy with VM 26 and CCNU in primary malignant brain tumors.
    Surgical neurology, 1979, Volume: 11, Issue:3

    Topics: Adolescent; Adult; Aged; Brain Neoplasms; Child; Drug Therapy, Combination; Female; Humans; Lomustine; Male; Middle Aged; Neoplasm Recurrence, Local; Nitrosourea Compounds; Podophyllotoxin; Teniposide

1979
Malignant gliomas treated after surgery by combination chemotherapy and delayed irradiation. Part I: Analysis of results.
    Acta neurochirurgica, 1979, Volume: 51, Issue:1-2

    Topics: Adolescent; Adult; Aged; Astrocytoma; Brain Neoplasms; Cobalt Radioisotopes; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Lomustine; Male; Middle Aged; Neoplasm Recurrence, Local; Nitrosourea Compounds; Podophyllotoxin; Radiotherapy Dosage; Teniposide

1979
Malignant gliomas treated after surgery by combination chemotherapy and delayed radiation therapy. Part II. Tolerance to irradiation after chemotherapy.
    Acta neurochirurgica, 1979, Volume: 51, Issue:1-2

    Topics: Brain; Brain Neoplasms; Drug Therapy, Combination; Glioma; Humans; Lomustine; Neoplasm Recurrence, Local; Nitrosourea Compounds; Podophyllotoxin; Radiation Tolerance; Radiotherapy; Radiotherapy Dosage; Teniposide

1979
A quantitative microdensitometric and autoradiographic study of the effect of 4'-demethyl-epipodophyllotoxin-beta-D-thenylidene glucoside (VM-26) on the cell cycle of cultured fibroblasts.
    The Histochemical journal, 1979, Volume: 11, Issue:6

    Topics: Animals; Cell Cycle; Cell Nucleus; Cells, Cultured; Chick Embryo; DNA; Fibroblasts; Mitochondria; Mitosis; Podophyllotoxin; Proteins; RNA; Teniposide

1979
[Effectiveness of VM 26, mitomycine C and methotrexate in advanced breast cancer refractory to a four drug combination (author's transl)].
    Bulletin du cancer, 1979, Volume: 66, Issue:5

    Topics: Adult; Aged; Breast Neoplasms; Drug Resistance; Drug Therapy, Combination; Female; Humans; Methotrexate; Middle Aged; Mitomycins; Neoplasm Metastasis; Podophyllotoxin; Teniposide

1979
Uridine enhances the chemotherapeutic action of the 4'-demethylepipodophyllotoxin-thenylidene-glucoside (VM 26)-cyclophosphamide combination on i.m. implanted Ehrlich carcinoma.
    Arzneimittel-Forschung, 1978, Volume: 28, Issue:3

    Topics: Animals; Carcinoma, Ehrlich Tumor; Cyclophosphamide; Drug Synergism; Drug Therapy, Combination; Female; Mice; Neoplasm Transplantation; Podophyllotoxin; Teniposide; Transplantation, Homologous; Uridine

1978
Epipodophyllotoxin VM-26 in the treatment of childhood neuroblastoma.
    Cancer treatment reports, 1977, Volume: 61, Issue:7

    Topics: Blood Cells; Child; Child, Preschool; Drug Evaluation; Female; Humans; Infusions, Parenteral; Male; Neuroblastoma; Podophyllotoxin; Teniposide

1977
Iv methyl-CCNU, VM-26, and cranial irradiation in therapy for malignant brain tumors.
    Cancer treatment reports, 1977, Volume: 61, Issue:9

    Topics: Brain Neoplasms; Humans; Injections, Intravenous; Leukopenia; Nitrosourea Compounds; Podophyllotoxin; Semustine; Teniposide

1977
Comparison of uptake and binding of two epipodophyllotoxin glucopyranosides, 4'-demethyl epipodophyllotoxin thenylidene-beta-D-glucoside and 4'-demethyl epipodophyllotoxin ethylidene-beta-D-glucoside, in the L1210 leukemia cell.
    Cancer research, 1978, Volume: 38, Issue:8

    Topics: Animals; Binding Sites; Biological Transport; Cell Nucleus; Etoposide; Kinetics; Leukemia L1210; Mice; Mice, Inbred DBA; Podophyllotoxin; Teniposide; Thermodynamics; Vinblastine

1978
Structure-activity study of the inhibition of microtubule assembly in vitro by podophyllotoxin and its congeners.
    Cancer research, 1978, Volume: 38, Issue:9

    Topics: Animals; Etoposide; In Vitro Techniques; Magnetic Resonance Spectroscopy; Microtubules; Podophyllotoxin; Stereoisomerism; Structure-Activity Relationship; Teniposide; Tubulin

1978
Kinetics of cytotoxicity of VM-26 and VP-16-213 on L1210 leukemia and hematopoietic stem cells.
    Cancer treatment reports, 1978, Volume: 62, Issue:9

    Topics: Animals; Cell Survival; Colony-Forming Units Assay; Dose-Response Relationship, Drug; Etoposide; Hematopoietic Stem Cells; Leukemia L1210; Podophyllotoxin; Rats; Teniposide; Time Factors

1978
Combined chemotherapy with VM 26 and BCNU for recurrent malignant gliomas after operation and irradiation.
    Acta neurochirurgica, 1978, Volume: 42, Issue:1-2

    Topics: Adult; Aged; Brain Neoplasms; Carmustine; Drug Therapy, Combination; Female; Glioma; Humans; Male; Middle Aged; Podophyllotoxin; Postoperative Period; Teniposide

1978
The role of drug disposition kinetics on cellular transport of the antineoplastic agent VM-26.
    Drug metabolism reviews, 1978, Volume: 8, Issue:1

    Topics: Animals; Biological Transport, Active; Chemical Phenomena; Chemistry; Diffusion; Etoposide; Kinetics; Leukemia L1210; Mice; Models, Biological; Podophyllotoxin; Protein Binding; Serum Albumin; Teniposide

1978
[Adriamycin, VM 26, cyclophosphamide and prednisone (AVmCP) combination in the therapy of disseminated lymphoreticulosarcoma (Stages or topographical forms III and IV].
    La Nouvelle presse medicale, 1975, Dec-20, Volume: 4, Issue:44

    Topics: Adolescent; Adult; Aged; Child; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Drug Tolerance; Female; Humans; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Middle Aged; Neoplasm Seeding; Podophyllotoxin; Prednisone; Remission, Spontaneous; Teniposide

1975
VM26-induced changes in hepatic intermediary metabolism of mice.
    Cancer research, 1977, Volume: 37, Issue:9

    Topics: Animals; Blood Glucose; Doxorubicin; Drug Synergism; Female; Glucose; Hexosephosphates; In Vitro Techniques; Isocitrates; Ketoglutaric Acids; Leukemia L1210; Liver; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mitochondria, Liver; Oxygen Consumption; Podophyllotoxin; Succinates; Teniposide

1977
VM 26 (4-demethyl-epipodophyllotoxin-beta-d-thenylidine glucoside) in the treatment of urinary bladder tumors.
    Neoplasma, 1977, Volume: 24, Issue:4

    Topics: Carcinoma, Papillary; Humans; Podophyllotoxin; Recurrence; Remission, Spontaneous; Teniposide; Time Factors; Urinary Bladder Neoplasms

1977
Antimetastasis effect of two derivatives of epiposophyllotoxin in mice.
    European journal of cancer, 1976, Volume: 12, Issue:10

    Topics: Animals; Etoposide; Lung Neoplasms; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Podophyllotoxin; Solvents; Teniposide; Time Factors

1976
Delayed toxicity of epipodophyllotoxin derivatives (VM 26 and VP 16-213), due to a local effect.
    European journal of cancer, 1976, Volume: 12, Issue:11

    Topics: Animals; Dose-Response Relationship, Drug; Etoposide; Female; Injections, Intraperitoneal; Injections, Intravenous; Leukemia L1210; Liver; Lung; Male; Mice; Organ Size; Podophyllotoxin; Rats; Teniposide; Time Factors

1976
Treatment of malignant gliomas and brain metastases in adults with a combination of adriamycin, VM 26, and CCNU. Results of a phase II trail.
    Cancer, 1976, Volume: 38, Issue:5

    Topics: Adult; Aged; Brain Neoplasms; Doxorubicin; Drug Therapy, Combination; Drug Tolerance; Female; Glioma; Hematologic Diseases; Humans; Intracranial Pressure; Lomustine; Male; Middle Aged; Nausea; Neoplasm Metastasis; Nitrosourea Compounds; Podophyllotoxin; Teniposide; Vomiting

1976
Comparison of the human pharmacokinetics of VM-26 and VP-16, two antineoplastic epipodophyllotixin glucopyranoside derivatives.
    European journal of cancer, 1975, Volume: 11, Issue:10

    Topics: Body Water; Etoposide; Humans; Metabolic Clearance Rate; Models, Biological; Neoplasms; Podophyllotoxin; Teniposide

1975
Response of L1210 to combinations of cytosine arabinoside and VM-26 or VP16-213.
    European journal of cancer, 1975, Volume: 11, Issue:9

    Topics: Animals; Cytarabine; Drug Therapy, Combination; Etoposide; Female; Leukemia L1210; Leukemia, Experimental; Mice; Podophyllotoxin; Pyrans; Teniposide

1975
Combination chemotherapy based on a model of cell recruitment by partial synchronization.
    Medical and pediatric oncology, 1975, Volume: 1, Issue:2

    Topics: Drug Therapy, Combination; Humans; Mitosis; Mitotic Index; Models, Biological; Neoplasm Metastasis; Neoplasms; Podophyllotoxin; Remission, Spontaneous; Teniposide; Time Factors; Vincristine

1975
Synthesis and biological activity of galactopyranoside derivatives of 4'-demethylepipodophyllotoxin showing VP-16 (etoposide)-like activity.
    Anti-cancer drug design, 1991, Volume: 6, Issue:5

    Topics: Acetals; Animals; Antineoplastic Agents; CHO Cells; Cricetinae; DNA; DNA Damage; Etoposide; Galactose; Podophyllotoxin; Structure-Activity Relationship; Teniposide

1991
Tests for the genotoxicity of m-AMSA, etoposide, teniposide and ellipticine in Neurospora crassa.
    Mutation research, 1990, Volume: 240, Issue:2

    Topics: Alkaloids; Amsacrine; Ellipticines; Etoposide; Molecular Structure; Mutagenicity Tests; Mutagens; Neurospora crassa; Podophyllotoxin; Teniposide

1990
Topoisomerase I and II cleavage of adenovirus DNA in vivo: both topoisomerase activities appear to be required for adenovirus DNA replication.
    Journal of virology, 1990, Volume: 64, Issue:1

    Topics: Adenovirus Early Proteins; Adenoviruses, Human; Camptothecin; DNA Replication; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA, Viral; HeLa Cells; Humans; Kinetics; Oncogene Proteins, Viral; Podophyllotoxin; Teniposide; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors

1990
Transcription of adenovirus and HeLa cell genes in the presence of drugs that inhibit topoisomerase I and II function.
    Nucleic acids research, 1990, Mar-25, Volume: 18, Issue:6

    Topics: Adenovirus Early Proteins; Adenoviruses, Human; Antigens, Viral, Tumor; Camptothecin; Exons; Genes; Genes, Viral; Heat-Shock Proteins; HeLa Cells; Humans; Kinetics; Oncogene Proteins, Viral; Podophyllotoxin; RNA, Messenger; Teniposide; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Transcription, Genetic

1990
Inhibition of topoisomerase II does not inhibit transcription of RNA polymerase I and II genes.
    Molecular and cellular biology, 1990, Volume: 10, Issue:6

    Topics: Animals; Chromatin; Female; Genes; Kinetics; Oocytes; Plasmids; Podophyllotoxin; Recombination, Genetic; RNA Polymerase I; RNA Polymerase II; RNA, Ribosomal; Teniposide; Thymidine Kinase; Topoisomerase II Inhibitors; Transcription, Genetic; Xenopus laevis

1990
Effects of the DNA topoisomerase II inhibitor, VM26, on transcriptional initiation in vitro.
    Life sciences, 1990, Volume: 46, Issue:18

    Topics: Animals; Cells, Cultured; Cloning, Molecular; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Podophyllotoxin; Prolactin; Promoter Regions, Genetic; Rats; Teniposide; Topoisomerase II Inhibitors; Transcription, Genetic

1990
Decreased nuclear matrix DNA topoisomerase II in human leukemia cells resistant to VM-26 and m-AMSA.
    Biochemistry, 1990, May-01, Volume: 29, Issue:17

    Topics: Amsacrine; Animals; Antineoplastic Agents; Cell Nucleus; Crithidia; DNA; DNA Topoisomerases, Type II; Drug Resistance; Humans; Leukemia; Podophyllotoxin; Teniposide; Tumor Cells, Cultured

1990
Reduction of drug accumulation and DNA topoisomerase II activity in acquired teniposide-resistant human cancer KB cell lines.
    Cancer research, 1990, Sep-15, Volume: 50, Issue:18

    Topics: DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Drug Resistance; Etoposide; Humans; KB Cells; Podophyllotoxin; Temperature; Teniposide

1990
Pharmacokinetics of intrapleural versus intravenous etoposide (VP 16) and teniposide (VM 26) in patients with malignant pleural effusion.
    Oncology, 1990, Volume: 47, Issue:1

    Topics: Aged; Etoposide; Female; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Pleural Effusion; Podophyllotoxin; Teniposide

1990
Partitioning of teniposide into membranes and the role of lipid composition.
    Biochimica et biophysica acta, 1990, Jan-29, Volume: 1021, Issue:2

    Topics: Etoposide; Kinetics; Lipid Bilayers; Models, Biological; Phosphatidylcholines; Podophyllotoxin; Structure-Activity Relationship; Teniposide; Tritium

1990
Phase II study of teniposide (VM26) in cutaneous T-cell lymphomas.
    American journal of clinical oncology, 1990, Volume: 13, Issue:1

    Topics: Adult; Aged; Drug Evaluation; Female; Humans; Lymphoma; Male; Middle Aged; Mycosis Fungoides; Podophyllotoxin; Prognosis; Remission Induction; Sezary Syndrome; Skin Neoplasms; T-Lymphocytes; Teniposide

1990
Phase II study of teniposide in advanced breast cancer.
    Cancer chemotherapy and pharmacology, 1990, Volume: 25, Issue:6

    Topics: Adult; Aged; Breast Neoplasms; Drug Administration Schedule; Drug Evaluation; Female; Humans; Infusions, Intravenous; Leukopenia; Middle Aged; Podophyllotoxin; Teniposide; Thrombocytopenia

1990
Teniposide (VM-26) in patients with non-squamous-cell carcinoma of the cervix. A phase II trial of the Gynecologic Oncology Group.
    American journal of clinical oncology, 1990, Volume: 13, Issue:2

    Topics: Adult; Aged; Carcinoma; Drug Administration Schedule; Drug Evaluation; Female; Humans; Middle Aged; Podophyllotoxin; Prognosis; Teniposide; Uterine Cervical Neoplasms

1990
Precipitation of teniposide during infusion.
    American journal of hospital pharmacy, 1990, Volume: 47, Issue:3

    Topics: Chemistry, Pharmaceutical; Drug Stability; Infusions, Intravenous; Podophyllotoxin; Teniposide

1990
Teniposide in recurrent or advanced cervical carcinoma: a phase II trial in patients not previously treated with cytotoxic therapy.
    Gynecologic oncology, 1990, Volume: 37, Issue:2

    Topics: Adult; Aged; Carcinoma; Drug Evaluation; Female; Humans; Leukopenia; Middle Aged; Neoplasm Recurrence, Local; Podophyllotoxin; Survival; Teniposide; Uterine Cervical Neoplasms

1990
Effects of the lipophilic anticancer drug teniposide (VM-26) on membrane transport.
    Chemico-biological interactions, 1990, Volume: 75, Issue:1

    Topics: Amino Acids; Animals; Biological Transport; Carcinoma, Ehrlich Tumor; Carrier Proteins; Cell Membrane; Cell Membrane Permeability; Cytarabine; Etoposide; Humans; Membrane Lipids; Membranes, Artificial; Nucleosides; Podophyllotoxin; Teniposide; Tumor Cells, Cultured

1990
Vidarabin-monophosphate, BCNU, VM26--an in vitro comparative study of active agents in the treatment of malignant human brain tumours.
    British journal of cancer, 1987, Volume: 55, Issue:2

    Topics: Adolescent; Aged; Arabinonucleotides; Brain Neoplasms; Carmustine; Cells, Cultured; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Humans; Kinetics; Male; Middle Aged; Neoplastic Stem Cells; Podophyllotoxin; RNA, Neoplasm; Teniposide; Vidarabine Phosphate

1987
VM-26 (teniposide)-induced hypersensitivity and degranulation of basophils in children.
    The American journal of pediatric hematology/oncology, 1988,Winter, Volume: 10, Issue:4

    Topics: Adolescent; Allergens; Basophils; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Hypersensitivity; Female; Histamine Release; Humans; Infant; Male; Neuroblastoma; Podophyllotoxin; Polyethylene Glycols; Risk Factors; Teniposide

1988
DNA minor groove binding agents interfere with topoisomerase II mediated lesions induced by epipodophyllotoxin derivative VM-26 and acridine derivative m-AMSA in nuclei from L1210 cells.
    Biochemistry, 1989, May-02, Volume: 28, Issue:9

    Topics: Amsacrine; Animals; Bisbenzimidazole; Cell Nucleus; Deoxyribonucleoproteins; Distamycins; DNA Damage; DNA, Neoplasm; Indoles; Kinetics; Leukemia L1210; Mice; Podophyllotoxin; Teniposide; Topoisomerase II Inhibitors

1989
Studies of topoisomerase-specific antitumor drugs in human lymphocytes using rabbit antisera against recombinant human topoisomerase II polypeptide.
    Cancer research, 1989, Feb-15, Volume: 49, Issue:4

    Topics: Animals; Antibodies; Base Sequence; Camptothecin; Chromosome Aberrations; Cloning, Molecular; DNA Replication; DNA Topoisomerases, Type II; Escherichia coli; Genes; Genetic Vectors; Humans; Immune Sera; Lymphocyte Activation; Lymphocytes; Molecular Sequence Data; Podophyllotoxin; Rabbits; Recombinant Proteins; Teniposide; Topoisomerase II Inhibitors

1989
Reduced formation of lesions in the DNA of a multidrug-resistant L1210 subline selected for teniposide resistance.
    Cancer chemotherapy and pharmacology, 1989, Volume: 23, Issue:3

    Topics: Animals; DNA; DNA Damage; DNA Topoisomerases, Type II; Doxorubicin; Drug Resistance; Leukemia L1210; Podophyllotoxin; Potassium Cyanide; Teniposide; Tumor Cells, Cultured; Verapamil

1989
Genetic characterization of the multidrug-resistant phenotype of VM-26-resistant human leukemic cells.
    Cancer research, 1989, May-01, Volume: 49, Issue:9

    Topics: Culture Media; DNA Topoisomerases, Type II; DNA, Neoplasm; Drug Resistance; Humans; Hybrid Cells; Leukemia, T-Cell; Phenotype; Podophyllotoxin; Teniposide; Tumor Cells, Cultured

1989
Evidence for the reversibility of cellular DNA lesion induced by mammalian topoisomerase II poisons.
    The Journal of biological chemistry, 1989, Jun-15, Volume: 264, Issue:17

    Topics: Animals; Cell Line; DNA Damage; HeLa Cells; Mice; Podophyllotoxin; Substrate Specificity; Teniposide; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors

1989
A study of drug-induced topoisomerase II-mediated DNA lesions on episomal chromatin.
    The Journal of biological chemistry, 1989, Sep-25, Volume: 264, Issue:27

    Topics: Amsacrine; Blotting, Southern; Cell Line; Chromatin; Dexamethasone; DNA Damage; DNA Topoisomerases, Type II; Genes; Kinetics; Plasmids; Podophyllotoxin; Teniposide

1989
Altered formation of DNA in human cells treated with inhibitors of DNA topoisomerase II (etoposide and teniposide).
    Cancer research, 1989, Nov-15, Volume: 49, Issue:22

    Topics: DNA Replication; DNA, Neoplasm; Etoposide; Humans; Kinetics; Melanoma; Podophyllotoxin; Teniposide; Thymidine; Topoisomerase II Inhibitors; Tumor Cells, Cultured

1989
Increased ATP requirement for activity of and complex formation by DNA topoisomerase II from human leukemic CCRF-CEM cells selected for resistance to teniposide.
    Cancer communications, 1989, Volume: 1, Issue:2

    Topics: Adenosine Triphosphate; Adenylyl Imidodiphosphate; Amsacrine; Cell Line; Cell Nucleus; DNA Topoisomerases, Type I; DNA, Neoplasm; Drug Resistance; Humans; Kinetics; Podophyllotoxin; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Binding; Teniposide; Tumor Cells, Cultured

1989
Expression of protein-associated DNA damage in the alkaline elution assay in the absence of enzymatic deproteinization.
    Cancer communications, 1989, Volume: 1, Issue:3

    Topics: Animals; Cell Line; DNA Damage; DNA Replication; DNA Topoisomerases, Type II; DNA, Neoplasm; Endopeptidase K; Etoposide; Humans; Hydrogen-Ion Concentration; Leukemia L1210; Liver Neoplasms, Experimental; Mice; Mitoxantrone; Podophyllotoxin; Protein Binding; Rats; Serine Endopeptidases; Teniposide; Tumor Cells, Cultured

1989
Anaphylactic reactions to teniposide.
    Lancet (London, England), 1989, Feb-18, Volume: 1, Issue:8634

    Topics: Adolescent; Anaphylaxis; Child; Child, Preschool; Etoposide; Humans; Infusions, Intravenous; Podophyllotoxin; Teniposide

1989
Teniposide-induced hypersensitivity reactions in children.
    Lancet (London, England), 1989, Jul-01, Volume: 2, Issue:8653

    Topics: Anaphylaxis; Child; Humans; Podophyllotoxin; Polyethylene Glycols; Teniposide

1989
[VM-26 and VP-16 salvage therapy for refractory germinal testicular cancers].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 1989, Volume: 80, Issue:11

    Topics: Adult; Choriocarcinoma; Dysgerminoma; Etoposide; Humans; Male; Middle Aged; Podophyllotoxin; Teniposide; Teratoma; Testicular Neoplasms

1989
Automated reversed-phase chromatographic analysis of etoposide and teniposide in plasma by using on-line surfactant-mediated sample clean-up and column-switching.
    Journal of chromatography, 1989, Oct-27, Volume: 495

    Topics: Chromatography, High Pressure Liquid; Electrochemistry; Etoposide; Humans; Podophyllotoxin; Spectrometry, Fluorescence; Teniposide

1989
[Phase I trial and pharmacokinetics of VM 26 combined with cisplatin administered by the intraperitoneal route without mixing time].
    Bulletin du cancer, 1989, Volume: 76, Issue:8

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Evaluation; Humans; Injections, Intraperitoneal; Middle Aged; Neoplasms; Podophyllotoxin; Teniposide

1989
Phase I/pharmacokinetic study of intraperitoneal teniposide (VM 26).
    European journal of cancer & clinical oncology, 1989, Volume: 25, Issue:5

    Topics: Abdominal Neoplasms; Adult; Aged; Ascites; Bone Marrow; Drug Evaluation; Female; Humans; Infusions, Parenteral; Male; Middle Aged; Podophyllotoxin; Teniposide

1989
A pharmacokinetic model for intraperitoneal administration of drugs: application to teniposide in humans.
    Journal of pharmaceutical sciences, 1989, Volume: 78, Issue:5

    Topics: Adolescent; Half-Life; Humans; Injections, Intraperitoneal; Models, Biological; Podophyllotoxin; Teniposide

1989
Effects of the anticancer agent VM-26 on hexose uptake in Ehrlich cells.
    Cancer biochemistry biophysics, 1989, Volume: 10, Issue:3

    Topics: 3-O-Methylglucose; Animals; Carcinoma, Ehrlich Tumor; Cytochalasin B; Deoxyglucose; Hexokinase; Hexoses; Kinetics; Male; Methylglucosides; Mice; Mice, Inbred Strains; Monosaccharide Transport Proteins; Phosphorylation; Podophyllotoxin; Teniposide; Tumor Cells, Cultured

1989
Treatment strategies in relation to drug action.
    NCI monographs : a publication of the National Cancer Institute, 1987, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; DNA Topoisomerases, Type II; Etoposide; Hodgkin Disease; Humans; Leukemia; Lung Neoplasms; Lymphoma, Non-Hodgkin; Neoplasms; Podophyllotoxin; Teniposide

1987
Involvement of intracellular ATP in cytotoxicity of topoisomerase II-targetting antitumor drugs.
    NCI monographs : a publication of the National Cancer Institute, 1987, Issue:4

    Topics: Adenosine Triphosphate; Camptothecin; Cell Survival; Cell Transformation, Neoplastic; Dinitrophenols; HeLa Cells; Humans; Kinetics; Podophyllotoxin; Simian virus 40; Teniposide; Topoisomerase II Inhibitors

1987
Elevated topoisomerase II activity and altered chromatin in nitrogen mustard-resistant human cells.
    NCI monographs : a publication of the National Cancer Institute, 1987, Issue:4

    Topics: Amsacrine; Burkitt Lymphoma; Cell Line; Cell Survival; Chromatin; DNA Topoisomerases, Type II; Drug Resistance; Humans; Kinetics; Mechlorethamine; Novobiocin; Podophyllotoxin; Teniposide; Tumor Stem Cell Assay

1987
Pharmacokinetics of VM 26 given intrapericardially or intravenously in patients with malignant pericardial effusion.
    Cancer chemotherapy and pharmacology, 1987, Volume: 20, Issue:3

    Topics: Aged; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Chromatography, High Pressure Liquid; Humans; Infusions, Intravenous; Infusions, Parenteral; Lung Neoplasms; Male; Middle Aged; Pericardial Effusion; Pericardium; Podophyllotoxin; Teniposide

1987
Topoisomerase-II-mediated lesions in nascent DNA: comparison of the effects of epipodophyllotoxin derivatives, VM-26 and VP-16, and 9-anilinoacridine derivatives, m-AMSA and o-AMSA.
    Biochimica et biophysica acta, 1988, May-06, Volume: 950, Issue:1

    Topics: Adenosine Triphosphate; Amsacrine; Animals; Cross-Linking Reagents; DNA; DNA Damage; DNA Replication; DNA Topoisomerases, Type II; DNA, Neoplasm; Etoposide; Leukemia L1210; Mice; Novobiocin; Podophyllotoxin; Teniposide; Topoisomerase II Inhibitors

1988
Teniposide (VM26): an effective treatment for brain metastases of small cell carcinoma of the lung.
    European journal of cancer & clinical oncology, 1988, Volume: 24, Issue:4

    Topics: Aged; Brain Neoplasms; Carcinoma, Small Cell; Female; Humans; Leukopenia; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin; Teniposide; Thrombocytopenia

1988
Teniposide in the treatment of small-cell lung cancer: the influence of prior chemotherapy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1988, Volume: 6, Issue:8

    Topics: Aged; Carcinoma, Small Cell; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin; Prognosis; Teniposide

1988
DNA binding by epipodophyllotoxins and N-acyl anthracyclines: implications for mechanism of topoisomerase II inhibition.
    Molecular pharmacology, 1988, Volume: 34, Issue:4

    Topics: Antibiotics, Antineoplastic; DNA; DNA, Mitochondrial; Etoposide; In Vitro Techniques; Plasmids; Podophyllotoxin; Teniposide; Topoisomerase II Inhibitors

1988
Effects of VM26, a specific inhibitor of type II DNA topoisomerase, on SV40 chromatin replication in vitro.
    Nucleic acids research, 1988, Nov-11, Volume: 16, Issue:21

    Topics: Animals; Aphidicolin; Cell Line; Chromatin; Diterpenes; DNA Replication; DNA Topoisomerases, Type I; Kinetics; Podophyllotoxin; Simian virus 40; Teniposide; Topoisomerase II Inhibitors; Virus Replication

1988
Unexpected high toxicity in a phase II study of teniposide (VM-26) in elderly patients with untreated small cell lung cancer (SCLC).
    European journal of cancer & clinical oncology, 1988, Volume: 24, Issue:11

    Topics: Aged; Aged, 80 and over; Carcinoma, Small Cell; Drug Evaluation; Female; Humans; Leukopenia; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin; Teniposide

1988
Podophyllotoxins for brain metastases of small cell lung cancer.
    Journal of neuro-oncology, 1988, Volume: 6, Issue:3

    Topics: Brain Neoplasms; Carcinoma, Small Cell; Etoposide; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin; Teniposide

1988
Induction of sister chromatid exchanges by inhibitors of topoisomerases.
    Cell biology and toxicology, 1986, Volume: 2, Issue:4

    Topics: Amsacrine; Animals; Camptothecin; Cells, Cultured; Cricetinae; DNA Topoisomerases, Type I; Enzyme Inhibitors; Fibroblasts; Podophyllotoxin; Sister Chromatid Exchange; Teniposide

1986
Successful induction with chemotherapy including teniposide in familial erythrophagocytic lymphohistiocytosis.
    Lancet (London, England), 1986, Dec-13, Volume: 2, Issue:8520

    Topics: Child, Preschool; Drug Evaluation; Erythrocytes; Humans; Infant; Lymphatic Diseases; Lymphocytes; Male; Phagocytosis; Podophyllotoxin; Remission Induction; Teniposide

1986
Pharmacological, molecular, and cytogenetic analysis of "atypical" multidrug-resistant human leukemic cells.
    Cancer research, 1987, Oct-15, Volume: 47, Issue:20

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Chloroquine; Chromosome Banding; Chromosomes, Human, Pair 13; Colchicine; Dactinomycin; Drug Resistance; Drug Screening Assays, Antitumor; Humans; Leukemia; Membrane Glycoproteins; Molecular Weight; Podophyllotoxin; Teniposide; Tumor Cells, Cultured; Verapamil; Vinblastine; Vinca Alkaloids

1987
Identification of DNA topoisomerase II as an intracellular target of antitumor epipodophyllotoxins in simian virus 40-infected monkey cells.
    Cancer research, 1985, Volume: 45, Issue:11 Pt 2

    Topics: Animals; Cells, Cultured; Chemical Precipitation; DNA Topoisomerases, Type II; DNA, Viral; Etoposide; Haplorhini; Novobiocin; Podophyllotoxin; Simian virus 40; Teniposide

1985
Peroxidative free radical formation and O-demethylation of etoposide(VP-16) and teniposide(VM-26).
    Biochemical and biophysical research communications, 1986, Feb-26, Volume: 135, Issue:1

    Topics: Chromatography, High Pressure Liquid; Electron Spin Resonance Spectroscopy; Etoposide; Free Radicals; Horseradish Peroxidase; Mass Spectrometry; Oxidoreductases, O-Demethylating; Peroxides; Podophyllotoxin; Prostaglandin-Endoperoxide Synthases; Quinones; Teniposide

1986
Teniposide (VM-26), an overlooked highly active agent in small-cell lung cancer. Results of a phase II trial in untreated patients.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1986, Volume: 4, Issue:4

    Topics: Aged; Carcinoma, Small Cell; Drug Administration Schedule; Drug Evaluation; Humans; Lung Neoplasms; Middle Aged; Neoplasm Metastasis; Podophyllotoxin; Teniposide

1986
DNA breakage in human lung carcinoma cells and nuclei that are naturally sensitive or resistant to etoposide and teniposide.
    Cancer research, 1986, Volume: 46, Issue:8

    Topics: Adenocarcinoma; Adenosine Triphosphate; Carcinoma, Small Cell; Cell Division; Cell Nucleus; Cells, Cultured; DNA; DNA, Single-Stranded; Drug Resistance; Etoposide; Humans; Intercalating Agents; Lung Neoplasms; Podophyllotoxin; Teniposide; Topoisomerase II Inhibitors

1986
A case of small cell lung cancer successfully treated with VM26.
    Japanese journal of clinical oncology, 1986, Volume: 16, Issue:2

    Topics: Aged; Carcinoma, Small Cell; Drug Evaluation; Humans; Lung Neoplasms; Male; Podophyllotoxin; Teniposide

1986
Membrane ordering effects of the anticancer agent VM-26.
    Biochimica et biophysica acta, 1986, Dec-16, Volume: 863, Issue:2

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Carcinoma, Ehrlich Tumor; Cell Line; Cell Membrane; Cholesterol; Cyclic N-Oxides; Dimyristoylphosphatidylcholine; Electron Spin Resonance Spectroscopy; Etoposide; Humans; Leukemia; Lipid Bilayers; Liposomes; Male; Membrane Lipids; Mice; Podophyllotoxin; Spin Labels; Teniposide

1986
Teniposide in the treatment of non-small cell lung carcinoma.
    Cancer treatment reports, 1987, Volume: 71, Issue:1

    Topics: Adult; Aged; Carcinoma, Non-Small-Cell Lung; Drug Evaluation; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin; Teniposide

1987
Effects of VM26 (teniposide), a specific inhibitor of type II DNA topoisomerase, on SV40 DNA replication in vivo.
    Nucleic acids research, 1987, Apr-24, Volume: 15, Issue:8

    Topics: Animals; Cell Line; DNA Replication; DNA, Viral; Podophyllotoxin; Simian virus 40; Teniposide; Topoisomerase II Inhibitors; Virus Replication

1987
Protein-linked DNA strand breaks produced by etoposide and teniposide in mouse L1210 and human VA-13 and HT-29 cell lines: relationship to cytotoxicity.
    NCI monographs : a publication of the National Cancer Institute, 1987, Issue:4

    Topics: Animals; Cell Line; Cell Survival; DNA Topoisomerases, Type II; DNA, Neoplasm; Etoposide; Humans; Kinetics; Leukemia L1210; Podophyllotoxin; Teniposide

1987
Uptake and binding of teniposide (VM26) in Krebs II ascites cells.
    Biochemical pharmacology, 1987, May-15, Volume: 36, Issue:10

    Topics: Animals; Biological Transport; Carcinoma, Krebs 2; Chromatography, High Pressure Liquid; Edetic Acid; Female; Iodoacetamide; Kinetics; Mice; Ouabain; Podophyllotoxin; Sodium; Teniposide

1987
Structure-bioactivation relationship of a series of podophyllotoxin derivatives.
    European journal of cancer & clinical oncology, 1988, Volume: 24, Issue:9

    Topics: Animals; Cell Survival; Cytochrome P-450 Enzyme System; Etoposide; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Podophyllotoxin; Rats; Rats, Inbred Strains; Spectrophotometry; Structure-Activity Relationship; Teniposide

1988
[Cytosine arabinoside and VM-26 in induction treatment, failures and recurrences of childhood acute lymphoblastic leukemias].
    Anales espanoles de pediatria, 1988, Volume: 29 Suppl 34

    Topics: Child; Child, Preschool; Cytarabine; Drug Combinations; Female; Humans; Male; Podophyllotoxin; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Risk Factors; Teniposide

1988
Etoposide (VP16) and teniposide (VM26): novel anticancer drugs, strongly mutagenic in mammalian but not prokaryotic test systems.
    Mutagenesis, 1987, Volume: 2, Issue:3

    Topics: Animals; Cell Line; Escherichia coli; Etoposide; Hypoxanthine Phosphoribosyltransferase; L Cells; Mice; Mutagenicity Tests; Mutagens; Mutation; Podophyllotoxin; Salmonella typhimurium; Teniposide

1987
Phase II evaluation of teniposide (VM-26) in metastatic breast carcinoma. A Southeastern Cancer Study Group trial.
    Investigational new drugs, 1988, Volume: 6, Issue:1

    Topics: Adult; Aged; Breast Neoplasms; Drug Evaluation; Drug Resistance; Female; Humans; Middle Aged; Neoplasm Metastasis; Podophyllotoxin; Teniposide

1988
[Use of VM-26 as a single agent in the treatment of transitional cell carcinoma of the urinary tract].
    Nihon Gan Chiryo Gakkai shi, 1988, May-20, Volume: 23, Issue:5

    Topics: Adult; Aged; Carcinoma, Transitional Cell; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Podophyllotoxin; Teniposide; Ureteral Neoplasms; Urinary Bladder Neoplasms

1988
Synthesis and structure-activity relationships among glycosidic derivatives of 4'-demethylepipodophyllotoxin and epipodophyllotoxin, showing VM26- and VP16-213-like activities.
    Anti-cancer drug design, 1987, Volume: 2, Issue:1

    Topics: Antineoplastic Agents; Cell Line; Drug Resistance; Etoposide; Podophyllotoxin; Structure-Activity Relationship; Teniposide

1987
Synthesis and biological activities of the C-4 esters of 4'-demethylepipodophyllotoxin.
    Anti-cancer drug design, 1987, Volume: 2, Issue:1

    Topics: Antineoplastic Agents; Cell Line; Drug Resistance; Esters; Etoposide; Mitotic Index; Podophyllotoxin; Structure-Activity Relationship; Teniposide

1987
Atypical multiple drug resistance in a human leukemic cell line selected for resistance to teniposide (VM-26).
    Cancer research, 1987, Mar-01, Volume: 47, Issue:5

    Topics: Cell Line; Drug Resistance; Flow Cytometry; Humans; Leukemia, Lymphoid; Podophyllotoxin; Teniposide

1987
Teniposide (VM-26) and ara-C in the treatment of adult acute lymphoblastic leukemia.
    Seminars in oncology, 1987, Volume: 14, Issue:2 Suppl 1

    Topics: Adult; Antigens, Surface; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Lymphoid; Male; Middle Aged; Podophyllotoxin; Prednisone; Prognosis; Teniposide; Vincristine

1987
Teniposide (VM-26) and cytosine arabinoside as consolidation therapy in adult high-risk patients with acute lymphoblastic leukemia.
    Seminars in oncology, 1987, Volume: 14, Issue:2 Suppl 1

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Leukemia, Lymphoid; Middle Aged; Podophyllotoxin; Prognosis; Teniposide

1987
Severe hypertensive reactions to teniposide (VM-26) in infants with congenital leukemia.
    The American journal of pediatric hematology/oncology, 1987,Fall, Volume: 9, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Hypertension; Infant; Infant, Newborn; Leukemia, Lymphoid; Leukemia, Myeloid; Podophyllotoxin; Teniposide

1987
Hypersensitivity reactions to teniposide (VM-26): an analysis.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1986, Volume: 4, Issue:8

    Topics: Adolescent; Adult; Aged; Bibliographies as Topic; Blood Pressure; Brain Neoplasms; Child; Child, Preschool; Data Collection; Drug Evaluation; Drug Hypersensitivity; Edema; Humans; Hypersensitivity, Immediate; Infant; Leukemia; Male; Middle Aged; Neuroblastoma; Podophyllotoxin; Surveys and Questionnaires; Teniposide; Urticaria

1986
Total-body irradiation and high-dose teniposide: a pilot study in bone marrow transplantation for patients with relapsed acute lymphoblastic leukemia.
    Cancer treatment reports, 1987, Volume: 71, Issue:6

    Topics: Adolescent; Adult; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Female; Humans; Leukemia, Lymphoid; Male; Pilot Projects; Podophyllotoxin; Teniposide; Whole-Body Irradiation

1987
[Familial erythrocyto-phagocytic lymphohistiocytosis--successful treatment of 4 children].
    Lakartidningen, 1987, Feb-11, Volume: 84, Issue:7

    Topics: Child, Preschool; Erythrocytes; Female; Histiocytes; Humans; Infant; Lymphatic Diseases; Lymphocytes; Male; Phagocytosis; Podophyllotoxin; Syndrome; Teniposide

1987
Expressions of resistance and cross-resistance in teniposide-resistant L1210 cells.
    Cancer chemotherapy and pharmacology, 1987, Volume: 19, Issue:2

    Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Line; Cyanides; Drug Resistance; Leukemia L1210; Lipid Metabolism; Mice; Neoplasm Proteins; Phenotype; Podophyllotoxin; Teniposide; Verapamil

1987
Pharmacokinetics of high-dose teniposide.
    Cancer treatment reports, 1987, Volume: 71, Issue:6

    Topics: Adult; Chromatography, High Pressure Liquid; Female; Humans; Kinetics; Male; Mathematics; Middle Aged; Podophyllotoxin; Teniposide

1987
Clinical pharmacodynamics of continuous infusion teniposide: systemic exposure as a determinant of response in a phase I trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:7

    Topics: Child; Drug Administration Schedule; Drug Evaluation; Humans; Infusions, Parenteral; Kinetics; Leukemia; Lymphoma; Neuroblastoma; Podophyllotoxin; Teniposide

1987
The role of histamine in doxorubicin and teniposide-induced cardiotoxicity in dog and mouse.
    Tumori, 1987, Jun-30, Volume: 73, Issue:3

    Topics: Animals; Chlorpheniramine; Dogs; Doxorubicin; Female; Heart; Histamine; Male; Mice; Myocardium; Podophyllotoxin; Teniposide

1987
Teniposide in squamous cell carcinoma of the cervix: a phase II trial of the Gynecologic Oncology Group.
    Cancer treatment reports, 1987, Volume: 71, Issue:9

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Drug Evaluation; Female; Humans; Middle Aged; Podophyllotoxin; Teniposide; Uterine Cervical Neoplasms

1987
Hypersensitivity reactions to teniposide in children.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:9

    Topics: Adolescent; Antineoplastic Agents; Child; Child, Preschool; Drug Hypersensitivity; Female; Humans; Infant; Male; Podophyllotoxin; Teniposide

1987
Teniposide is not effective in chronic lymphocytic leukemia.
    Blut, 1986, Volume: 52, Issue:1

    Topics: Adult; Aged; Drug Evaluation; Female; Humans; Infusions, Parenteral; Leukemia, Lymphoid; Male; Middle Aged; Podophyllotoxin; Teniposide

1986
Non-Hodgkin's lymphomas in the elderly: prospective studies with specifically devised chemotherapy regimens in 66 patients.
    European journal of cancer & clinical oncology, 1987, Volume: 23, Issue:5

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Drug Evaluation; Etoposide; Female; Humans; Lymphoma, Non-Hodgkin; Male; Podophyllotoxin; Prednimustine; Prospective Studies; Teniposide

1987
Teniposide (VM-26) in patients with advanced refractory ovarian cancer: a phase II study of the Netherlands Joint Study Group for Ovarian Cancer.
    European journal of cancer & clinical oncology, 1987, Volume: 23, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Drug Evaluation; Female; Hematologic Diseases; Humans; Nausea; Ovarian Neoplasms; Podophyllotoxin; Prognosis; Teniposide

1987
Teniposide in metastatic renal and bladder cancer: a Southwest Oncology Group Study.
    Cancer treatment reports, 1987, Volume: 71, Issue:12

    Topics: Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Female; Humans; Kidney Neoplasms; Male; Podophyllotoxin; Teniposide; Urinary Bladder Neoplasms

1987
Comparison between VP 16 and VM 26 in Lewis lung carcinoma of the mouse.
    European journal of cancer & clinical oncology, 1986, Volume: 22, Issue:2

    Topics: Animals; Body Weight; Cell Count; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Etoposide; Kinetics; Leukocyte Count; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Podophyllotoxin; Teniposide

1986
Quantification of teniposide in human serum by high-performance liquid chromatography with electrochemical detection.
    Journal of chromatography, 1986, Mar-07, Volume: 375, Issue:2

    Topics: Carcinoma; Chromatography, High Pressure Liquid; Electrochemistry; Etoposide; Female; Humans; Indicators and Reagents; Ovarian Neoplasms; Podophyllotoxin; Teniposide; Time Factors

1986
High-dose teniposide for refractory malignancies: a phase I study.
    Cancer treatment reports, 1986, Volume: 70, Issue:5

    Topics: Adult; Aged; Alopecia; Drug Evaluation; Female; Hematologic Diseases; Humans; Male; Middle Aged; Nausea; Neoplasms; Podophyllotoxin; Skin Diseases; Teniposide

1986
Teniposide-induced changes in the physical properties of phosphatidylcholine liposomes. A calorimetric study.
    Biochemical pharmacology, 1986, Aug-15, Volume: 35, Issue:16

    Topics: Antineoplastic Agents; Calorimetry; Liposomes; Mathematics; Phosphatidylcholines; Podophyllotoxin; Teniposide; Thermodynamics

1986
[Mutagenicity tests of etoposide and teniposide].
    The Journal of toxicological sciences, 1986, Volume: 11 Suppl 1

    Topics: Animals; Etoposide; Male; Mice; Mutagenicity Tests; Podophyllotoxin; Teniposide

1986
Pharmacokinetics and efficacy of i.v. and i.p. VM26 chemotherapy in mice bearing Krebs II ascitic tumors.
    European journal of cancer & clinical oncology, 1986, Volume: 22, Issue:7

    Topics: Animals; Carcinoma, Krebs 2; Dose-Response Relationship, Drug; Female; Half-Life; Injections, Intraperitoneal; Injections, Intravenous; Kinetics; Mice; Podophyllotoxin; Teniposide

1986
The effect of the two epipodophyllotoxin derivatives etoposide (VP-16) and teniposide (VM-26) on cell lines established from patients with small cell carcinoma of the lung.
    Cancer chemotherapy and pharmacology, 1987, Volume: 19, Issue:1

    Topics: Animals; Carcinoma, Squamous Cell; Cell Cycle; Cell Line; Cell Survival; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Resistance; Etoposide; Lung Neoplasms; Podophyllotoxin; Teniposide

1987
Mutagenicity and clastogenicity of teniposide (VM-26) in L5178Y/TK +/- -3.7.2C mouse lymphoma cells.
    Mutation research, 1987, Volume: 187, Issue:3

    Topics: Animals; Carcinogens; Chromosome Aberrations; Chromosome Disorders; Leukemia L5178; Leukemia, Experimental; Mice; Mutagenicity Tests; Mutagens; Mutation; Podophyllotoxin; Teniposide; Thymidine Kinase

1987
Single- and double-strand DNA breakage and repair in human lung adenocarcinoma cells exposed to etoposide and teniposide.
    Cancer research, 1985, Volume: 45, Issue:7

    Topics: Adenocarcinoma; Aminoacridines; Amsacrine; Cells, Cultured; DNA; DNA Repair; Etoposide; Humans; Lung Neoplasms; Podophyllotoxin; Teniposide

1985
A novel treatment of childhood lymphoblastic non-Hodgkin's lymphoma: early and intermittent use of teniposide plus cytarabine.
    Blood, 1985, Volume: 66, Issue:5

    Topics: Adolescent; Child; Child, Preschool; Cytarabine; Drug Therapy, Combination; Female; Humans; Infant; Injections, Spinal; Lymphoma; Male; Methotrexate; Podophyllotoxin; Prognosis; Teniposide; Thymus Gland

1985
Allergic reactions to teniposide in patients with neuroblastoma and lymphoid malignancies.
    Cancer treatment reports, 1985, Volume: 69, Issue:4

    Topics: Child; Child, Preschool; Diphenhydramine; Drug Hypersensitivity; Humans; Leukemia, Lymphoid; Lymphoma; Neuroblastoma; Podophyllotoxin; Teniposide

1985
Phase II trial of teniposide in previously treated and untreated patients with advanced colorectal carcinoma: an Illinois Cancer Council Trial.
    Cancer treatment reports, 1986, Volume: 70, Issue:2

    Topics: Colonic Neoplasms; Drug Evaluation; Female; Humans; Male; Middle Aged; Podophyllotoxin; Rectal Neoplasms; Teniposide

1986
Pharmacokinetics of teniposide in patients with ovarian cancer.
    Cancer treatment reports, 1985, Volume: 69, Issue:1

    Topics: Adult; Ascites; Female; Humans; Infusions, Parenteral; Kinetics; Middle Aged; Ovarian Neoplasms; Podophyllotoxin; Teniposide; Time Factors

1985
Inhibition of 1-beta-D-arabinofuranosylcytosine transport and net accumulation by teniposide and etoposide in Ehrlich ascites cells and human leukemic blasts.
    Cancer research, 1985, Volume: 45, Issue:7

    Topics: Animals; Binding Sites; Biological Transport; Carcinoma, Ehrlich Tumor; Cells, Cultured; Cytarabine; Etoposide; Humans; Leukemia; Male; Mice; Mice, Inbred Strains; Podophyllotoxin; Teniposide; Thioinosine; Tritium

1985
Pharmacokinetics of teniposide (VM 26) after IV administration in serum and malignant ascites of patients with ovarian carcinoma.
    Cancer chemotherapy and pharmacology, 1985, Volume: 15, Issue:2

    Topics: Aged; Ascitic Fluid; Carcinoma; Chromatography, High Pressure Liquid; Electrochemistry; Female; Humans; Kinetics; Mathematics; Metabolic Clearance Rate; Ovarian Neoplasms; Podophyllotoxin; Proteins; Teniposide

1985
Sequential cis-platinum and VM26 in neuroblastoma: laboratory and clinical (OPEC regimen) studies.
    Progress in clinical and biological research, 1985, Volume: 175

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Survival; Cells, Cultured; Child; Child, Preschool; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Drug Evaluation; Drug Synergism; Humans; Infant; Neuroblastoma; Podophyllotoxin; Prognosis; Teniposide; Vincristine

1985
Serum protein reduction of the enhancement of methotrexate accumulation by vincristine and 4'-demethylepipodophyllotoxin in the Ehrlich ascites tumor cell in vitro.
    Cancer research, 1985, Volume: 45, Issue:12 Pt 1

    Topics: Animals; Biological Transport; Blood Proteins; Carcinoma, Ehrlich Tumor; Cells, Cultured; Male; Methotrexate; Mice; Podophyllotoxin; Teniposide; Vincristine

1985
Radioimmunoassay for etoposide and teniposide.
    Journal of immunological methods, 1985, Dec-17, Volume: 85, Issue:1

    Topics: Animals; Antibody Affinity; Cross Reactions; Dogs; Etoposide; Humans; Liver; Metabolic Clearance Rate; Mice; Podophyllotoxin; Rabbits; Radioimmunoassay; Teniposide

1985
[VM-26 salvage therapy for refractory or recurrent germinal testicular cancers].
    Hinyokika kiyo. Acta urologica Japonica, 1985, Volume: 31, Issue:9

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dysgerminoma; Humans; Male; Neoplasm Recurrence, Local; Podophyllotoxin; Teniposide; Teratoma; Testicular Neoplasms

1985
Nonintercalative antitumor drugs interfere with the breakage-reunion reaction of mammalian DNA topoisomerase II.
    The Journal of biological chemistry, 1984, Nov-10, Volume: 259, Issue:21

    Topics: Animals; Cattle; DNA, Neoplasm; Etoposide; HeLa Cells; Humans; Kinetics; Phosphorus Radioisotopes; Podophyllotoxin; Teniposide; Thymus Gland; Topoisomerase II Inhibitors

1984
Role of topoisomerase II in mediating epipodophyllotoxin-induced DNA cleavage.
    Cancer research, 1984, Volume: 44, Issue:12 Pt 1

    Topics: Animals; Cattle; Cell Nucleus; Cell Survival; DNA Topoisomerases, Type II; DNA, Neoplasm; Etoposide; Leukemia L1210; Mice; Podophyllotoxin; Structure-Activity Relationship; Teniposide; Thymus Gland

1984
Phase II study of teniposide in small cell carcinoma of the lung.
    Cancer treatment reports, 1984, Volume: 68, Issue:10

    Topics: Adult; Aged; Carcinoma, Small Cell; Drug Evaluation; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin; Teniposide

1984
Acute intravascular haemolysis and renal failure due to teniposide related antibody.
    Lancet (London, England), 1981, Jun-27, Volume: 1, Issue:8235

    Topics: Acute Kidney Injury; Anemia, Hemolytic; Antibodies; Humans; Male; Middle Aged; Podophyllotoxin; Teniposide

1981
[Chemotherapy of papillomatoses of the larynx].
    Ceskoslovenska otolaryngologie, 1980, Volume: 29, Issue:1

    Topics: Bleomycin; Humans; Laryngeal Neoplasms; Male; Papilloma; Podophyllotoxin; Teniposide

1980
Normal infant after combination chemotherapy including teniposide for Burkitt's lymphoma in pregnancy.
    Medical and pediatric oncology, 1982, Volume: 10, Issue:2

    Topics: Adult; Antineoplastic Agents; Bleomycin; Burkitt Lymphoma; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fetus; Humans; Methotrexate; Podophyllotoxin; Prednisolone; Pregnancy; Pregnancy Complications; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Teniposide; Vincristine

1982
Teniposide (VM-26)- and etoposide (VP-16-213)-induced augmentation of methotrexate transport and polyglutamylation in Ehrlich ascites tumor cells in vitro.
    Cancer research, 1982, Volume: 42, Issue:9

    Topics: Animals; Biological Transport; Carcinoma, Ehrlich Tumor; Cells, Cultured; Chlorides; Etoposide; Glucose; Kinetics; Methotrexate; Mice; Peptides; Podophyllotoxin; Polyglutamic Acid; Teniposide; Vincristine; Water

1982
VM-26 monochemotherapy trial in the treatment of recurrent supratentorial gliomas: preliminary report.
    Surgical neurology, 1981, Volume: 15, Issue:2

    Topics: Anemia; Astrocytoma; Brain Neoplasms; Chemical and Drug Induced Liver Injury; Female; Glioblastoma; Glioma; Humans; Kidney Diseases; Male; Neoplasm Recurrence, Local; Oligodendroglioma; Podophyllotoxin; Teniposide

1981
Combination chemotherapy for metastatic brain tumors.
    Tumori, 1981, Dec-31, Volume: 67, Issue:6

    Topics: Adenocarcinoma; Brain Neoplasms; Breast Neoplasms; Carcinoma, Small Cell; Doxorubicin; Drug Therapy, Combination; Humans; Lomustine; Lung Neoplasms; Nitrosourea Compounds; Podophyllotoxin; Prognosis; Teniposide; Tomography, X-Ray Computed

1981
[Antimitotic chemotherapy of supratentorial cerebral glioma in adults. Apropos of 56 cases].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1983, Feb-17, Volume: 59, Issue:7

    Topics: Adult; Aged; Brain Neoplasms; Drug Therapy, Combination; Female; Glioma; Humans; Lomustine; Male; Middle Aged; Nitrosourea Compounds; Podophyllotoxin; Teniposide

1983
Inhibition of the DNA catenation activity of type II topoisomerase by VP16-213 and VM26.
    Biochemical and biophysical research communications, 1984, Jul-18, Volume: 122, Issue:1

    Topics: Animals; DNA Topoisomerases, Type I; DNA, Neoplasm; Etoposide; Liver Neoplasms, Experimental; Podophyllotoxin; Rats; Structure-Activity Relationship; Teniposide; Topoisomerase II Inhibitors

1984
A phase II trial of teniposide (VM 26) in advanced non-Hodgkin's lymphoma, with emphasis on the treatment of elderly patients.
    Cancer, 1984, Aug-01, Volume: 54, Issue:3

    Topics: Adult; Age Factors; Aged; Asthenia; Drug Evaluation; Female; Humans; Leukopenia; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Middle Aged; Podophyllotoxin; Teniposide; Thrombocytopenia

1984
[Action of alkaloids from podophyllin on the response of pancreatic beta-cells of the rabbit to tolbutamide].
    Revista espanola de oncologia, 1983, Volume: 30, Issue:4

    Topics: Animals; Etoposide; Insulin; Insulin Secretion; Islets of Langerhans; Podophyllotoxin; Rabbits; Teniposide; Tolbutamide

1983
Pharmacokinetic study of VM26 given as a prolonged IV infusion to ovarian cancer patients.
    Cancer chemotherapy and pharmacology, 1984, Volume: 13, Issue:3

    Topics: Animals; Drug Administration Schedule; Female; Injections, Intravenous; Kinetics; Metabolic Clearance Rate; Ovarian Neoplasms; Podophyllotoxin; Teniposide

1984
Phase II study of VM 26 in extensively pretreated breast cancer.
    American journal of clinical oncology, 1984, Volume: 7, Issue:5

    Topics: Adult; Aged; Breast Neoplasms; Drug Evaluation; Female; Humans; Male; Middle Aged; Podophyllotoxin; Teniposide

1984
Penetration of teniposide (VM-26) into human intracerebral tumors. Preliminary observations on the effect of tumor type, rate of drug infusion and prior treatment with amphotericin B or oral glycerol.
    Journal of neuro-oncology, 1984, Volume: 2, Issue:4

    Topics: Amphotericin B; Astrocytoma; Brain Neoplasms; Glycerol; Humans; Kinetics; Meningioma; Podophyllotoxin; Teniposide

1984
Establishment of an etoposide-resistant human epithelial tumour cell line in vitro: characterization of patterns of cross-resistance and drug sensitivities.
    International journal of cancer, 1984, May-15, Volume: 33, Issue:5

    Topics: Carcinoma, Squamous Cell; Cell Line; Cisplatin; DNA, Neoplasm; Drug Resistance; Etoposide; Fluorouracil; Humans; Podophyllotoxin; Teniposide; Tongue Neoplasms; Vincristine; X-Rays

1984
Comparative cytotoxic and cytokinetic effects of the epipodophyllotoxins 4'-demethylepipodophyllotoxin-9-(4,6-O-2-ethylidene-beta-D-glucopyranoside) and 4'-demethylepipodophyllotoxin-9-(4,6-O-2-thenylidene-beta-D-glucopyranoside) and their metabolites on
    Cancer research, 1983, Volume: 43, Issue:12 Pt 1

    Topics: Cell Cycle; Cell Line; Cell Survival; Clone Cells; Dose-Response Relationship, Drug; Etoposide; Humans; Kinetics; Leukemia, Lymphoid; Podophyllotoxin; Structure-Activity Relationship; Teniposide

1983
Teniposide (VM26) disposition in children with leukemia.
    Cancer research, 1984, Volume: 44, Issue:3

    Topics: Child; Child, Preschool; Female; Humans; Kinetics; Leukemia, Lymphoid; Male; Metabolic Clearance Rate; Podophyllotoxin; Teniposide

1984
4'-Demethylepipodophyllotoxin-beta-D-glucoside: a new podophyllotoxin derivative with VM-26-like and VP-16-213-like activities.
    Journal of the National Cancer Institute, 1984, Volume: 73, Issue:1

    Topics: Animals; Cell Line; Cricetinae; Cricetulus; Drug Resistance; Etoposide; Female; Ovary; Podophyllotoxin; Structure-Activity Relationship; Teniposide

1984
[VM-26 and cytosine arabinoside in the treatment of acute refractory lymphoblastic leukemia in adults].
    Sangre, 1984, Volume: 29, Issue:4-A

    Topics: Adolescent; Adult; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cytarabine; Drug Evaluation; Female; Humans; Leukemia, Lymphoid; Male; Podophyllotoxin; Teniposide

1984
[Treatment of acute refractory lymphoblastic leukemia in the adult with VM-26 and ARA-C].
    Sangre, 1984, Volume: 29, Issue:6

    Topics: Adolescent; Adult; Child; Cytarabine; Female; Humans; Leukemia, Lymphoid; Male; Middle Aged; Podophyllotoxin; Teniposide

1984
Automated liquid chromatographic analysis of the anti-tumorigenic drugs etoposide (VP 16-213) and teniposide (VM 26).
    Journal of chromatography, 1983, Sep-09, Volume: 276, Issue:2

    Topics: Autoanalysis; Chromatography, Liquid; Etoposide; Humans; Hydrolysis; Podophyllotoxin; Teniposide

1983
Skin ulceration potential without therapeutic anticancer activity for epipodophyllotoxin commercial diluents.
    Investigational new drugs, 1983, Volume: 1, Issue:2

    Topics: Adenocarcinoma; Animals; Cell Survival; Colonic Neoplasms; Etoposide; Humans; Leukemia P388; Leukemia, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Podophyllotoxin; Skin Ulcer; Solvents; Teniposide; Tumor Stem Cell Assay

1983
High-performance liquid chromatographic analysis of the semisynthetic epipodophyllotoxins teniposide and etoposide using electrochemical detection.
    Journal of pharmaceutical sciences, 1984, Volume: 73, Issue:2

    Topics: Body Fluids; Chromatography, High Pressure Liquid; Electrochemistry; Etoposide; Humans; Kinetics; Podophyllotoxin; Teniposide

1984
Comparison of cytotoxicity and DNA breakage activity of congeners of podophyllotoxin including VP16-213 and VM26: a quantitative structure-activity relationship.
    Biochemistry, 1984, Mar-13, Volume: 23, Issue:6

    Topics: Adenocarcinoma; Cell Line; Cell Survival; DNA; DNA Repair; Etoposide; Humans; Kinetics; Lung Neoplasms; Podophyllotoxin; Structure-Activity Relationship; Teniposide

1984
Selection and characterization of L1210 sublines resistant to teniposide (VM-26).
    Cancer research, 1984, Volume: 44, Issue:7

    Topics: Animals; Cell Division; Chromosome Banding; Clone Cells; Drug Resistance; Karyotyping; Kinetics; Leukemia L1210; Metaphase; Mice; Mutation; Podophyllotoxin; Teniposide

1984
Flux of teniposide (VM-26) across the plasma membrane of teniposide-resistant sublines of L1210 cells.
    Cancer research, 1984, Volume: 44, Issue:7

    Topics: Animals; Biological Transport; Cell Membrane; Drug Resistance; Kinetics; Leukemia L1210; Mice; Mutation; Podophyllotoxin; Teniposide

1984
Teniposide in refractory ovarian cancer: a phase II study.
    Cancer treatment reports, 1984, Volume: 68, Issue:5

    Topics: Adult; Aged; Drug Evaluation; Female; Humans; Infusions, Parenteral; Leukopenia; Middle Aged; Nausea; Ovarian Neoplasms; Podophyllotoxin; Teniposide

1984
Etoposide (VP-16-213) in malignant brain tumors: a phase II study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1984, Volume: 2, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Drug Evaluation; Etoposide; Female; Glioma; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Podophyllotoxin; Teniposide; Time Factors; Tomography, X-Ray Computed

1984
New anticancer drug class.
    JAMA, 1983, Mar-25, Volume: 249, Issue:12

    Topics: Child; Etoposide; Humans; Legislation, Drug; Neoplasms; Podophyllotoxin; Teniposide; United States

1983
Genetic, biochemical, and cross-resistance studies with mutants of Chinese hamster ovary cells resistant to the anticancer drugs, VM-26 and VP16-213.
    Cancer research, 1983, Volume: 43, Issue:4

    Topics: Animals; Antineoplastic Agents; Biological Transport; Cell Line; Cricetinae; Cricetulus; Daunorubicin; Drug Resistance; Etoposide; Female; Mutation; Ovary; Phenotype; Podophyllotoxin; Teniposide

1983
Activity and pharmacokinetics of teniposide in Lewis lung carcinoma-bearing mice.
    Cancer treatment reports, 1983, Volume: 67, Issue:6

    Topics: Animals; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Half-Life; Kinetics; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Podophyllotoxin; Teniposide; Tissue Distribution

1983
VM-26 and cytosine arabinoside combination chemotherapy for initial induction failures in childhood lymphocytic leukemia.
    Cancer, 1980, Oct-15, Volume: 46, Issue:8

    Topics: Adolescent; Antineoplastic Agents; Bone Marrow Diseases; Child; Child, Preschool; Cytarabine; Drug Resistance; Drug Therapy, Combination; Female; Humans; Infant; Leukemia, Lymphoid; Male; Mercaptopurine; Methotrexate; Podophyllotoxin; Remission, Spontaneous; Teniposide

1980
VM26 in malignant hematological diseases. A phase II study.
    Cancer chemotherapy and pharmacology, 1982, Volume: 7, Issue:2-3

    Topics: Drug Evaluation; Hodgkin Disease; Humans; Leukemia, Lymphoid; Lymphoma; Multiple Myeloma; Podophyllotoxin; Teniposide

1982
Cardiovascular toxic effects of VM26 in the treatment of acute lymphatic leukemia. Presentation of two cases.
    Tumori, 1982, Jun-30, Volume: 68, Issue:3

    Topics: Cardiovascular System; Child; Heart Failure; Humans; Hypertension; Leukemia, Lymphoid; Male; Podophyllotoxin; Teniposide

1982
Glycosylated podophyllotoxin congeners: loss of microtubule inhibition and permission of invasion in vitro.
    Journal of the National Cancer Institute, 1982, Volume: 69, Issue:6

    Topics: Animals; Cell Division; Chick Embryo; Etoposide; Fibrosarcoma; Mice; Microtubules; Myocardium; Organ Culture Techniques; Podophyllotoxin; Teniposide

1982
VM-26 with prednisone and vincristine for treatment of refractory acute lymphocytic leukemia.
    Medical and pediatric oncology, 1982, Volume: 10, Issue:5

    Topics: Adolescent; Adult; Child; Child, Preschool; Drug Resistance; Drug Therapy, Combination; Humans; Leukemia, Lymphoid; Podophyllotoxin; Prednisone; Recurrence; Teniposide; Vincristine

1982
Phase II evaluation of VM-26 in patients with metastatic transitional cell carcinoma of the urinary tract: an Eastern Cooperative Oncology Group study.
    Cancer treatment reports, 1982, Volume: 66, Issue:2

    Topics: Aged; Carcinoma, Transitional Cell; Drug Evaluation; Female; Humans; Leukopenia; Male; Middle Aged; Neoplasm Metastasis; Podophyllotoxin; Teniposide; Urologic Neoplasms

1982
Immune hemolytic anemia and renal failure due to teniposide.
    The New England journal of medicine, 1982, May-06, Volume: 306, Issue:18

    Topics: Acute Kidney Injury; Anemia, Hemolytic, Autoimmune; Autoantibodies; Brain Neoplasms; Erythrocytes; Female; Humans; Kidney Tubular Necrosis, Acute; Male; Middle Aged; Podophyllotoxin; Teniposide

1982
Etoposide (VP16-213) and teniposide (VM26) comparative in vitro activities in human tumors.
    Cancer chemotherapy and pharmacology, 1982, Volume: 7, Issue:2-3

    Topics: Antineoplastic Agents; Cells, Cultured; Etoposide; Humans; Neoplasms; Neoplasms, Experimental; Podophyllotoxin; Teniposide

1982
Pharmacokinetics of Teniposide (VM26) and etoposide (VP16-213) in children with cancer.
    Cancer chemotherapy and pharmacology, 1982, Volume: 7, Issue:2-3

    Topics: Biotransformation; Child; Chromatography, High Pressure Liquid; Etoposide; Humans; Kinetics; Leukemia; Models, Biological; Neoplasms; Podophyllotoxin; Teniposide

1982
Combination chemotherapy of the epipodophyllotoxin derivatives, teniposide and etoposide. A pharmacodynamic rationale?
    Cancer chemotherapy and pharmacology, 1982, Volume: 7, Issue:2-3

    Topics: Adult; Aged; Ascitic Fluid; Drug Interactions; Drug Therapy, Combination; Etoposide; Female; Humans; Kinetics; Male; Middle Aged; Models, Biological; Podophyllotoxin; Protein Binding; Teniposide

1982
VM26 therapy in children with drug-refractory lymphocytic leukemia.
    Cancer chemotherapy and pharmacology, 1982, Volume: 7, Issue:2-3

    Topics: Child; Cytarabine; Drug Evaluation; Drug Resistance; Drug Therapy, Combination; Humans; Leukemia, Lymphoid; Podophyllotoxin; Prednisone; Teniposide; Vincristine

1982
Clinical evaluation of sequentially scheduled cisplatin and VM26 in neuroblastoma: response and toxicity.
    Cancer, 1981, Oct-15, Volume: 48, Issue:8

    Topics: Bone Marrow; Child; Child, Preschool; Cisplatin; Drug Administration Schedule; Drug Evaluation; Humans; Hypocalcemia; Magnesium; Mitotic Index; Neuroblastoma; Parathyroid Hormone; Podophyllotoxin; Prospective Studies; Teniposide

1981
Combined chemotherapy in the management of metastatic bladder cancer.
    British journal of urology, 1981, Volume: 53, Issue:4

    Topics: Doxorubicin; Drug Evaluation; Drug Therapy, Combination; Fluorouracil; Humans; Mitomycins; Neoplasm Metastasis; Podophyllotoxin; Teniposide; Urinary Bladder Neoplasms

1981
Analysis of the anticancer drugs etoposide (VP 16-213) and teniposide (VM 26) by high-performance liquid chromatography with fluorescence detection.
    Journal of chromatography, 1981, Jun-12, Volume: 224, Issue:1

    Topics: Chromatography, High Pressure Liquid; Etoposide; Humans; Podophyllotoxin; Reference Values; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Teniposide; Time Factors

1981
[Use of VM 26 (epipodophyllotoxin) in treating acute leukemias and lymphomas in the adult].
    Problemy gematologii i perelivaniia krovi, 1981, Volume: 26, Issue:7

    Topics: Acute Disease; Adult; Drug Evaluation; Hodgkin Disease; Humans; Leukemia; Lymphoma; Podophyllotoxin; Teniposide; Time Factors

1981
VM 26 in advanced mycosis fungoides.
    Tumori, 1981, Oct-31, Volume: 67, Issue:5

    Topics: Adult; Aged; Bone Marrow Diseases; Female; Humans; Male; Mycosis Fungoides; Podophyllotoxin; Skin Neoplasms; Splenic Neoplasms; Teniposide

1981
Combined VM-26 and cytosine arabinoside in treatment of refractory childhood lymphocytic leukemia.
    Cancer, 1980, Mar-15, Volume: 45, Issue:6

    Topics: Adolescent; Adult; Bone Marrow; Child; Child, Preschool; Cytarabine; Drug Resistance; Drug Therapy, Combination; Female; Humans; Hypotension; Leukemia, Lymphoid; Male; Podophyllotoxin; Recurrence; Remission, Spontaneous; Teniposide

1980
Phase II study of VM-26 in adult malignancies.
    Cancer treatment reports, 1980, Volume: 64, Issue:1

    Topics: Breast Neoplasms; Colonic Neoplasms; Drug Evaluation; Female; Glioma; Humans; Leukopenia; Male; Middle Aged; Neoplasms; Podophyllotoxin; Teniposide; Thrombocytopenia

1980
Analysis of the anticancer drugs VP 16-213 and VM 26 and their metabolites by high-performance liquid chromatography.
    Journal of chromatography, 1980, May-09, Volume: 182, Issue:2

    Topics: Adult; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Etoposide; Humans; Isomerism; Kinetics; Male; Podophyllotoxin; Spectrometry, Fluorescence; Teniposide

1980
Combination chemotherapy with VM 26 and CCNU in primary malignant brain tumors of children.
    Helvetica paediatrica acta, 1980, Volume: 35, Issue:1

    Topics: Adolescent; Brain Neoplasms; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Lomustine; Male; Nitrosourea Compounds; Podophyllotoxin; Teniposide

1980
Effect of VM-26 on the haematological responses of mice to L1210 leukaemia.
    British journal of cancer, 1980, Volume: 42, Issue:5

    Topics: Animals; Female; Hematocrit; Leukemia L1210; Leukocyte Count; Mice; Neoplasm Transplantation; Platelet Count; Podophyllotoxin; Teniposide; Transplantation, Homologous

1980
Sedimentation of DNA from L1210 cells after treatment with 4'-demethylepipodophyllotoxin-9-(4,6-O-2-thenylidene-beta-D-glucopyranoside) or 1-beta-D-arabinofuranosylcytosine or both drugs.
    Cancer research, 1980, Volume: 40, Issue:11

    Topics: Animals; Antibiotics, Antineoplastic; Centrifugation, Density Gradient; Cytarabine; Dose-Response Relationship, Drug; Drug Interactions; Leukemia L1210; Mice; Podophyllotoxin; Teniposide; Time Factors

1980
Intensive therapy with peripheral blood progenitor cell transplantation in 60 patients with poor-prognosis follicular lymphoma.
    Blood, 1995, Oct-15, Volume: 86, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carmustine; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Doxorubicin; Graft Rejection; Hematopoietic Cell Growth Factors; Hematopoietic Stem Cell Transplantation; Humans; Life Tables; Lymphoma, Follicular; Melphalan; Middle Aged; Pancytopenia; Podophyllotoxin; Prednisone; Prognosis; Teniposide; Treatment Outcome; Vincristine; Whole-Body Irradiation

1995
Induction of ovarian function by using short-term human menopausal gonadotrophin in patients with ovarian failure following cytotoxic chemotherapy for haematological malignancy.
    Leukemia & lymphoma, 1993, Volume: 10, Issue:4-5

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow Transplantation; Carmustine; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Female; Follicle Stimulating Hormone; Hodgkin Disease; Humans; Leukemia, Myelomonocytic, Acute; Luteinizing Hormone; Melphalan; Menotropins; Ovulation Induction; Podophyllotoxin; Prednisone; Pregnancy; Pregnancy, Multiple; Primary Ovarian Insufficiency; Remission Induction; Teniposide; Thioguanine; Vincristine

1993
[In vitro comparison of podophyllotoxin analogues; etoposide, teniposide and NK 611 using human lung cancer cell lines].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:4

    Topics: Adenocarcinoma; Antineoplastic Agents; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cell Division; Drug Resistance; Drug Screening Assays, Antitumor; Etoposide; Humans; Lung Neoplasms; Podophyllotoxin; Teniposide; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured

1993
Mechanisms of resistance of human small cell lung cancer lines selected in VP-16 and cisplatin.
    Cancer, 1996, May-01, Volume: 77, Issue:9

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cadmium; Cadmium Chloride; Carcinoma, Small Cell; Cell Line; Chlorides; Cisplatin; Cross Reactions; DNA; DNA Topoisomerases, Type II; Drug Resistance, Neoplasm; Etoposide; Gene Expression Regulation, Neoplastic; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Humans; Lung Neoplasms; Metallothionein; Platinum Compounds; Podophyllotoxin; Teniposide; Tumor Cells, Cultured; Vinca Alkaloids

1996
Discovery of podophyllotoxins.
    Biochimie, 1998, Volume: 80, Issue:3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Enzyme Inhibitors; Etoposide; History, 19th Century; History, 20th Century; Humans; Podophyllotoxin; Teniposide; Topoisomerase II Inhibitors

1998
Protein phosphorylation associated with epipodophyllotoxin-induced apoptosis of lymphoid cells: role of a serine/threonine protein kinase.
    Clinical immunology and immunopathology, 1998, Volume: 89, Issue:2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Dexamethasone; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme Inhibitors; Female; Mice; Mice, Inbred C3H; Phosphorylation; Podophyllotoxin; Protein Kinase C; Protein Serine-Threonine Kinases; Teniposide; Thymus Gland

1998
Effects of cranial radiation in children with high risk T cell acute lymphoblastic leukemia: a Pediatric Oncology Group report.
    Leukemia, 2000, Volume: 14, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System; Child; Child, Preschool; Cohort Studies; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Cytarabine; Disease-Free Survival; Female; Humans; Infant; Injections, Spinal; Leukemia-Lymphoma, Adult T-Cell; Leukemic Infiltration; Male; Methotrexate; Podophyllotoxin; Prognosis; Remission Induction; Risk; Teniposide; Treatment Outcome

2000
A Highly Efficient Approach To Construct (epi)-Podophyllotoxin-4-O-glycosidic Linkages as well as Its Application in Concise Syntheses of Etoposide and Teniposide.
    Organic letters, 2016, Mar-18, Volume: 18, Issue:6

    Topics: Antineoplastic Agents; Catalysis; Etoposide; Glycosides; Glycosylation; Molecular Structure; Podophyllotoxin; Teniposide

2016
A novel cell-based screening assay for small-molecule MYB inhibitors identifies podophyllotoxins teniposide and etoposide as inhibitors of MYB activity.
    Scientific reports, 2018, 09-03, Volume: 8, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; DNA Damage; Dose-Response Relationship, Drug; Etoposide; Gene Expression Regulation, Leukemic; High-Throughput Screening Assays; Humans; Leukocytes; Podophyllotoxin; Proto-Oncogene Proteins c-myb; Signal Transduction; Small Molecule Libraries; Teniposide

2018