arginine has been researched along with omega-n-methylarginine in 1929 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 30 (1.56) | 18.7374 |
| 1990's | 1685 (87.35) | 18.2507 |
| 2000's | 158 (8.19) | 29.6817 |
| 2010's | 45 (2.33) | 24.3611 |
| 2020's | 11 (0.57) | 2.80 |
| Authors | Studies |
|---|---|
| Fast, W; Hong, L | 1 |
| Lewis, DA; Miller, VM | 1 |
| Feinstein, DL; Galea, E; Reis, DJ | 1 |
| Boughton-Smith, NK; Deakin, AM; Whittle, BJ | 1 |
| Kim, S; Lee, YJ; Paik, WK; Rawal, N | 1 |
| Bredt, DS; Pou, S; Pou, WS; Rosen, GM; Snyder, SH | 1 |
| Bryant, JL; Mehta, JL; Mehta, P; Von der Porten, A | 1 |
| Cattell, V; Cook, HT; Jansen, A; Lewis, S | 1 |
| Gimeno, M; Lyson, K; McCann, SM; Rettori, V | 1 |
| Boughton-Smith, NK; Moncada, S; Whittle, BJ | 1 |
| Andrade, SP; Hart, IR; Piper, PJ | 1 |
| Moncada, S; Mulligan, MS; Ward, PA | 1 |
| Arakawa, N; Funakoshi, T; Hiramori, K; Nakamura, M; Suzuki, T; Yoshida, H | 1 |
| Fujiwara, M; Jino, H; Kurahashi, K; Mekata, F; Shirahase, H; Usui, H | 1 |
| Moncada, S; Nava, E; Palmer, RM | 1 |
| Chierchia, SL; Pellegatta, F; Poggi, A; Vidal, MJ; Zocchi, MR | 1 |
| Siragy, HM | 1 |
| Nakanishi, T; Nishimura, M; Takahashi, H; Tanaka, H; Yoshimura, M | 1 |
| Pearson, JD; Royston, BD; Royston, D | 1 |
| Lewis, MJ; Siney, L | 2 |
| Miyake, H; Ohuchi, T; Okabe, S; Sugawara, H; Takeuchi, K | 1 |
| Atkinson, AM; Teale, DM | 1 |
| Elmore, SP; Oliver, JD; Simpson, LM; Watts, JA | 1 |
| Dumont, JE; Esteves, RZ; van Sande, J | 1 |
| Busija, DW; Chen, J | 1 |
| Bray, K; Quast, U | 1 |
| Allen, NJ; Amrani, M; Harding, SE; Jayakumar, J; Moncada, S; O'Shea, J; Pepper, JR; Yacoub, MH | 1 |
| Anggard, E; Mollace, V; Pistelli, A; Salvemini, D; Vane, J | 2 |
| Ramwell, PW; Thomas, G | 3 |
| Freeman, RH; Johnson, RA | 1 |
| Billiar, TR; Curran, RD; Di Silvio, M; Harbrecht, BG; Murray, SA; Ochoa, JB; Simmons, RL; Stadler, J; Williams, DL | 1 |
| Harada, N; Kosaka, H; Shiga, T; Watanabe, M; Yoshihara, H | 1 |
| Carey, RM; Johns, RA; Peach, MJ; Siragy, HM | 1 |
| Ea Kim, L; Javellaud, J; Oudart, N | 1 |
| Chadee, K; Lin, JY | 1 |
| Faber, JE; Nishigaki, K; Ohyanagi, M | 1 |
| Hishikawa, K; Ikenaga, H; Kato, R; Nakaki, T; Saruta, T; Suzuki, H | 1 |
| Lazarides, E; Lin, JM; Wang, C | 1 |
| Fukuda, N; Hatano, M; Izumi, Y; Soma, M; Watanabe, M; Watanabe, Y | 1 |
| Goy, MF; McGehee, DS; Oxford, GS | 1 |
| Park, J; Rikihisa, Y | 1 |
| Lawson, DL; Mehta, JL; Mehta, P; Nichols, WW; Yang, BC | 1 |
| Harada, T; Hirayama, T; Kawabe, J; Morita, K; Ogawa, Y; Onodera, S; Takeda, A; Tobise, K | 2 |
| Aquino, L; Day, DB; Duerksen-Hughes, PJ; Gooding, LR; Laster, SM; Zachariades, NA | 1 |
| Cohen, RA; Gupta, S; McArthur, CS; Ruderman, NB; Sussman, I; Tornheim, K | 1 |
| Cailmail, S; Hadengue, A; Lebrec, D; Moreau, R; Oberti, F; Ohsuga, M; Pussard, E; Sogni, P | 1 |
| Calver, A; Collier, J; Moncada, S; Vallance, P | 1 |
| Billiar, TR; Curran, RD; Demetris, AJ; Harbrecht, BG; Ochoa, J; Simmons, RL; Stadler, J | 1 |
| Kato, M | 1 |
| dos Santos, IR; Duarte, ID; Ferreira, SH; Lorenzetti, BB | 1 |
| Fernández, MA; Fresno, M; Muñoz-Fernández, MA | 1 |
| Davies, B; Edwards, SW | 1 |
| Agulló, L; García, A | 2 |
| Balashov, SA; Kartamyshev, SP; Khaiutin, VM; Klimachev, AN; Mel'kumiants, AM | 1 |
| Corbett, JA; Lancaster, JR; McDaniel, ML; Sweetland, MA; Wang, JL | 2 |
| Barnes, PJ; Crawley, DE; Evans, TW; Liu, SF; Rohde, JA | 1 |
| Calver, A; Collier, J; Green, D; Vallance, P | 1 |
| Förstermann, U; Helgren, MC; Kimber, ND; Klabunde, RE; Kuk, JE | 1 |
| Day, RW; Ignarro, LJ; Klitzner, TS; Lai, WW | 1 |
| Adams, HR; Hotchkiss, RS; Karl, IE; Parker, JL | 1 |
| Cakmakci, M; Geroulanos, S; Jung, HH; Largiader, F; Schilling, J | 1 |
| Calver, A; Collier, J; Leone, A; Moncada, S; Vallance, P | 1 |
| Cohen, J; Silva, A | 1 |
| Beierwaltes, WH; Carretero, OA; Pegoraro, AA; Sigmon, DH | 1 |
| Conrad, KP; Whittemore, SL | 1 |
| Casado, MA; Marín, J; Pareja, A; Rodríguez-Mañas, L; Salaices, M; Sánchez-Ferrer, CF | 1 |
| Gupta, BB; Heil, K; Spessert, R; Vollrath, L | 1 |
| Aberdeen, J; Burnstock, G; Gaw, AJ; Humphrey, PP; Wadsworth, RM | 1 |
| Galligan, JJ; Osthaus, LE | 1 |
| Hacker, MP; Huot, AE; Kruszyna, H; Kruszyna, R; Smith, RP | 1 |
| Ishii, K; Murad, F; Schmidt, HH; Sheng, H; Warner, TD | 1 |
| Böhme, E; Heinzel, B; John, M; Klatt, P; Mayer, B | 1 |
| Schröder, H; Schrör, K; Strobach, H | 1 |
| Vane, JR; Zembowicz, A | 1 |
| Billiar, TR; Dull, KE; Hoffman, RA; Ildstad, ST; Langrehr, JM; Ochoa, JB; Schraut, WH; Simmons, RL | 1 |
| Brown, JF; Hanson, PJ; Moncada, S; Tepperman, BL; Whittle, BJ | 1 |
| Anderson, DC; Mulligan, MS; Rudolph, AR; Smith, CW; Ward, PA; Warren, JS; Yeh, CG | 1 |
| Bassetti, S; Keist, R; Keller, R; Klauser, S; Mülsch, A | 1 |
| Griffith, OW; Kilbourn, RG | 3 |
| Chang, K; Corbett, JA; Hasan, KS; Ido, Y; Lancaster, JR; McDaniel, ML; Sweetland, MA; Tilton, RG; Wang, JL; Williamson, JR | 1 |
| Billiar, TR; Di Silvio, M; Geller, DA; Hoffman, RA; Madariaga, J; Nussler, AK; Selby, R; Simmons, RL | 1 |
| Bennett, T; Gardiner, SM; Kemp, PA; Moncada, S; Palmer, RM | 2 |
| Gross, SS; Kitabatake, A; Kobayashi, T; Levi, R; Saito, H; Sakuma, I; Togashi, H; Yasuda, H; Yoshioka, M | 1 |
| Moncada, S; Radomski, MW; Smith, RE | 1 |
| Catravas, JD; Marczin, N; Ryan, US | 1 |
| Datto, GA; Wolff, DJ | 1 |
| Joyner, WL; Tang, T | 1 |
| Malawista, SE; Montgomery, RR; van Blaricom, G | 2 |
| Courtois, Y; Goureau, O; Lepoivre, M | 1 |
| Bogle, RG; Mann, GE; Moncada, S; Pearson, JD | 1 |
| Connor, HE; Feniuk, W; Stubbs, CM; Waldron, GJ | 1 |
| Garland, CJ; Rand, VE | 1 |
| Chen, TY; Crawford, RM; Green, SJ; Meltzer, MS; Morrison, DC; Nacy, CA | 1 |
| Gribkoff, VK; Lum-Ragan, JT | 1 |
| Archer, S; Peterson, DA; Peterson, DC; Weir, EK | 1 |
| Föstermann, U; Mitchell, JA; Murad, F; Nakane, M; Pollock, JS; Schmidt, HH; Sheng, H | 1 |
| Bhattacharya, J; Bhattacharya, S | 1 |
| Davies, JA; Dickie, BG; Lewis, MJ | 1 |
| Corbett, JA; Hughes, JH; Lancaster, JR; McDaniel, ML; Sweetland, MA; Wang, JL; Wolf, BA | 1 |
| Andrews, T; Foxwell, NA; Moncada, S; Palmer, RM | 1 |
| Panizzon, K; Wallis, RA; Wasterlain, CG | 1 |
| Cocks, T; Crack, P | 1 |
| Kato, R; Nakaki, T; Nakayama, M; Otsuka, Y | 1 |
| Bult, H; Herman, AG; Jorens, PG; Van Overveld, FJ; Vermeire, PA | 2 |
| Barnes, PJ; Haworth, SG; Hislop, AA; Liu, SF | 1 |
| Moncada, S; Palmer, RM; Vallance, P | 1 |
| Gazzinelli, RT; Hieny, S; James, SL; Oswald, IP; Sher, A | 1 |
| McGuigan, F; Sternberg, J | 1 |
| Ahokas, RA; Sibai, BM | 1 |
| McCarthy, AL; Poston, L; Taylor, PD; Thomas, CR | 1 |
| D'Orleans-Juste, P; Hecker, M; Mitchell, JA; Vane, JR; Wood, EG | 1 |
| Balashov, SA; Kartamyshev, SP; Khayutin, VM; Klimachev, AN; Melkumyants, AM | 1 |
| Billiar, TR; Curran, RD; Demetris, AJ; Harbrecht, BG; Ochoa, JB; Simmons, RL; Stadler, J | 1 |
| Bienzle, U; Chaves, MF; Kremsner, PG; Neifer, S; Rudolph, R | 1 |
| Kakimoto, Y; Kondoh, K; Kotani, K; Sano, A; Ueno, S | 1 |
| Aisaka, K; Hidaka, T; Ishihara, T; Kanai, T; Miyazaki, T; Ohno, T | 1 |
| Kontos, HA; Kukreja, R; Wei, EP | 1 |
| Beckmann, R; Goessl, C; Knispel, HH | 2 |
| Archer, SL; Hampl, V | 1 |
| Bucknall, CA; Moncada, S; Palmer, RM; Smith, RE | 1 |
| Gonzales, J; Lawson, DL; Mehta, JL; Nichols, WW; Nicolini, FA | 1 |
| Bosch, J; Fernández, M; Moncada, S; Piqué, JM; Pizcueta, P; Rodés, J; Whittle, BJ | 1 |
| Fischer-Stenger, K; Marciano-Cabral, F | 1 |
| Helgren, MC; Klabunde, RE | 1 |
| Buster, BL; Miller, RD; Powell, LA; Ramirez, JA; Summersgill, JT | 1 |
| Greenblatt, EP; Loeb, AL; Longnecker, DE | 2 |
| Akl, ES; Allen, SP; Chester, AH; Piper, PJ; Sampson, AP; Yacoub, MH | 1 |
| Calver, A; Collier, J; Vallance, P | 2 |
| Herrig, JE; Liu, KZ; Thompson, LP; Weiner, CP | 1 |
| Hori, M; Karaki, H; Sudjarwo, SA | 1 |
| Ferro, TJ; Johnson, A | 1 |
| Bassetti, S; Fischer, W; Keist, R; Keller, R | 1 |
| Aggarwal, BB; Awburn, MM; Clark, IA; Cowden, WB; Rockett, KA | 1 |
| Goldin, RD; Hunt, NC | 1 |
| Harasawa, Y; Hayashi, S; Kimura, M; Maeda, K; Nakamura, M; Ohno, Y; Sakurai, I | 1 |
| Jaraki, O; Keaney, J; Loscalzo, J; Osborne, J; Simon, DI; Singel, D; Stamler, JS; Valeri, CR; Vita, J | 1 |
| Hiramatsu, Y; Itokazu, Y; Kinoshita, T; Koida, M; Kurio, W; Maeda, H; Manno, K; Nakamuta, H; Ogawa, Y; Ozaki, K | 1 |
| Kajimoto, N; Mizusawa, H; Omote, M | 1 |
| Chilian, WM; Granger, HJ; Yuan, Y; Zawieja, DC | 1 |
| Andrews, JW; Brennan, GM; Hayes, JR; Henry, WR; Johnston, GD; McDermott, BJ; McGrath, LT; McVeigh, GE | 2 |
| Moncada, S; Rees, DD; Wright, CE | 1 |
| Casado, MA; Fernández-Alfonso, MS; González, R; Marín, J; Pareja, A; Ponte, A; Rodríguez-Mañas, L; Sánchez-Ferrer, CF | 1 |
| al-Ramadi, BK; Eisenstein, TK; Huang, D; Meissler, JJ | 1 |
| Heck, DE; Laskin, DL; Laskin, JD; Punjabi, CJ | 1 |
| Clifford, DB; Izumi, Y; Zorumski, CF | 1 |
| Mayhan, WG | 7 |
| Brink, C; Gorenne, I; Labat, C; Norel, X; Ortiz, JL; Verley, J | 1 |
| Christensen, G; Kiil, F; Kirkebøen, KA; Naess, PA | 2 |
| Gross, SS; Kobayashi, T; Levi, R; Saito, H; Sakuma, I; Tamura, M; Togashi, H; Yanagida, M; Yasuda, H; Yoshioka, M | 1 |
| Murray, HW; Teitelbaum, RF | 1 |
| Cummings, JJ; Morin, FC; Tiktinsky, MH | 1 |
| Bosnjak, ZJ; Buljubasic, N; Flynn, NM; Kampine, JP | 1 |
| Benjamin, N; Collier, J; Vallance, P | 1 |
| Bernard, C; Payen, D; Philip, I; Szekely, B; Tedgui, A; Wollman, E | 1 |
| Bergmann, L; Kolb, H; Kolb-Bachofern, V; Kröncke, KD; Suschek, C | 1 |
| Blankenhorn, EP; Fu, Y | 1 |
| Miura, K; Okumura, M; Yamamoto, K; Yamashita, Y; Yukimura, T | 1 |
| Koźniewska, E; Oseka, M; Styś, T | 1 |
| Hartung, HP; Tausch, M; Toyka, KV; Zielasek, J | 1 |
| Gray, DW; Marshall, I | 1 |
| Blantz, RC; De Nicola, L; Gabbai, FB | 1 |
| Katayose, D; Ogata, M; Ohe, M; Takishima, T | 1 |
| Bohlen, HG; Lash, JM | 2 |
| Hecker, M; Macarthur, H; Sessa, WC; Siegle, I; Vane, JR | 1 |
| Abou el Ezz, A; Billiar, TR; Hoffman, RA; Hronakes, ML; Ildstad, ST; Wren, SM | 1 |
| Kaley, G; Koller, A; Messina, EJ; Rodenburg, JM; Wolin, MS | 1 |
| Bennett, T; Gardiner, SM | 2 |
| Lee, L; Webb, RC | 1 |
| Auch-Schwelk, W; Katusić, ZS; Vanhoutte, PM | 1 |
| Iadecola, C | 1 |
| Burnett, JC; Hildebrand, FL; Lerman, A; Sandok, EK | 1 |
| Albert, U; Björnberg, J; Ekelund, U; Grände, PO; Mellander, S | 1 |
| Newman, CM; O'Shaughnessy, KM; Warren, JB | 1 |
| Nelson, GH; Nishimura, H; Rosenblum, WI | 2 |
| Loeb, AL; Longnecker, DE | 1 |
| Katusić, ZS | 2 |
| Banga, JD; de Graaf, JC; de Groot, PG; Moncada, S; Palmer, RM; Sixma, JJ | 1 |
| Calignano, A; Mancuso, F; Persico, P; Sorrentino, L | 2 |
| Barnes, PJ; Crawley, DE; Evans, TW; Liu, SF | 5 |
| Tepperman, BL; Whittle, BJ | 1 |
| Bosch, J; Moncada, S; Piqué, JM; Pizcueta, MP; Whittle, BJ | 1 |
| Lawson, DL; Mehta, JL; Nichols, WW; Yang, BC | 1 |
| Brunner, HR; Drexler, H; Hayoz, D; Hornig, B; Just, H; Münzel, T; Zelis, R | 1 |
| Pittner, RA; Spitzer, JA | 2 |
| Tabrizchi, R; Triggle, CR | 1 |
| Cohen, HJ; Currie, MS; Kilby, DL; Padmanabhan, J; Rao, KM; Weinberg, JB | 1 |
| Cathapermal, S; Farhat, M; Myers, A; Ramwell, PW; Thomas, G | 1 |
| Di Rosa, M; Ialenti, A; Ianaro, A; Moncada, S | 1 |
| Christes, A; Drexler, H; Hablawetz, E; Lu, W; Riede, U | 1 |
| Ayrancioglu, K; Evora, PR; Pearson, PJ; Schaff, HV | 1 |
| Ellis, EF; Nelson, GH; Nishimura, H; Rosenblum, WI | 1 |
| Berceli, SA; Borovetz, HS; Labadie, RF; Ligush, J; Ochoa, JB | 1 |
| Drexler, H; Lu, W | 1 |
| Ohlstein, EH; Storer, BL | 1 |
| Benz, AM; Clifford, DB; Izumi, Y; Zorumski, CF | 1 |
| De Kimpe, SJ; Nijkamp, FP; Van Heuven-Nolsen, D | 2 |
| Fozard, JR; Part, ML | 2 |
| Finkel, MS; Hattler, BG; Jacob, TD; Oddis, CV; Simmons, RL; Watkins, SC | 1 |
| Dembińska-Kieć, A; Pallapies, D; Peskar, BA; Simmet, T; Thelen, K | 1 |
| Estrada, C; Fernandez, A; Gonzalez, C; Martin, C; Moncada, S | 1 |
| Bosch, J; Casadevall, M; Panés, J; Piqué, JM; Terés, J; Whittle, BJ | 1 |
| Burnett, JC; Miller, VM | 1 |
| Langenstroer, P; Pieper, GM | 1 |
| Ishizaka, H; Okumura, K; Tsuchiya, T; Yamabe, H; Yasue, H | 2 |
| Burnett, JC; Cortese, DA; Edell, ES; Krowka, MJ; Perrella, MA | 1 |
| Brayden, JE; Uusitalo, H; Zschauer, A | 1 |
| Hotchkiss, JH; Jacob, JR; Liu, RH; Tennant, BC | 1 |
| Garside, P; Hutton, AK; Liew, FY; Mowat, AM; Severn, A | 1 |
| Heim, KF; Ramwell, PW; Thomas, G | 1 |
| Chaudhuri, G; Cuevas, JM; Ignarro, LJ; Vargas, HM | 1 |
| Azadzoi, KM; Goldstein, I; Kim, N; Saenz de Tejada, I | 1 |
| East, SJ; Garthwaite, J | 1 |
| Hevel, JM; Marletta, MA; Mulligan, MS; Ward, PA | 1 |
| Maragoudakis, ME; Pipili-Synetos, E; Sideri, E | 1 |
| Förstermann, U; Ishii, K; Murad, F; Sheng, H; Warner, TD | 1 |
| Cederqvist, B; Gustafsson, LE; Persson, MG; Wiklund, NP | 1 |
| Cohen, RA; Cowan, CL | 1 |
| Biondi, ML; Feletou, M; Peglion, JL; Vanhoutte, PM; Vilaine, JP; Villeneuve, N | 1 |
| Corbett, JA; Lancaster, JR; McDaniel, ML; Sweetland, MA | 2 |
| Chen, PY; Sanders, PW | 1 |
| Grinstein, S; Rotstein, OD; Sudsbury, RA; Swallow, CJ | 1 |
| Haught, WH; Hintze, T; Lawson, DL; Mehta, JL; Yang, BC | 1 |
| Chang, R; Fineman, JR; Soifer, SJ | 1 |
| Busse, R; Jackson, WF | 1 |
| Bosnjak, ZJ; Buljubasic, N; Flynn, N; Kampine, JP | 1 |
| Ichihara, A; Murakami, M; Naitoh, M; Nakamoto, H; Saruta, T; Suzuki, H | 1 |
| Boeckxstaens, GE; Bogers, JJ; De Man, JG; Herman, AG; Pelckmans, PA; Van Maercke, YM | 1 |
| Anania, V; Demontis, MP; Madeddu, P; Manunta, P; Parpaglia, PP; Pazzola, A; Soro, A; Tonolo, G; Troffa, C; Varoni, MV | 1 |
| Komas, N; Lugnier, C; Stoclet, JC | 1 |
| Badger, AM; Bugelski, PJ; Kaplan, JM; Newman-Tarr, T; Olivera, DL; Ruggieri, EV | 1 |
| Beasley, D; Brenner, BM; Schwartz, JH | 1 |
| Boeckxstaens, GE; Bogers, JJ; Bult, H; De Man, JG; Herman, AG; Oosterbosch, L; Pelckmans, PA; Van Maercke, YM | 1 |
| Hattori, R; Kadota, K; Kawai, C; Uchizumi, H; Yui, Y | 1 |
| Boeckxstaens, GE; Bult, H; De Man, JG; Herman, AG; Pelckmans, PA; van Maercke, YM | 2 |
| Desai, KM; Sessa, WC; Vane, JR | 1 |
| Granger, DN; Kubes, P; Suzuki, M | 1 |
| Duarte, ID; Ferreira, SH; Lorenzetti, BB | 1 |
| Bauer, E; Lüscher, TF; Stulz, P; Turina, M; von Segesser, L; Yang, ZH | 1 |
| Miller, VM | 1 |
| Desai, KM; Sessa, WC; Vane, JR; Zembowicz, A | 1 |
| Arroyo, CM; Forray, C | 1 |
| Aldasoro, M; Esplugues, JV; Flor, B; Lluch, S; Martinez-Cuesta, MA; Martinez-Martinez, MC; Vila, J | 1 |
| Alexander, B; Burnstock, G; Mathie, RT; Ralevic, V | 1 |
| Bauer, AJ; Stark, ME; Szurszewski, JH | 1 |
| Gillespie, JS; Sheng, H | 1 |
| Lang, D; Smith, JA | 1 |
| Cler, J; Emmett, MR; Iyengar, S; Mick, S; Rao, TS; Wood, PL | 1 |
| Knowles, RG; Moncada, S; Palacios, M; Palmer, RM | 1 |
| Chester, AH; Moncada, S; O'Neil, GS; Tadjkarimi, S; Yacoub, MH | 1 |
| Okamura, T; Toda, N | 3 |
| Hacker, MP; Huot, AE | 1 |
| Gustafsson, LE; Moncada, S; Persson, MG; Wiklund, CU; Wiklund, NP | 1 |
| Moncada, S; Palmer, RM; Radomski, MW | 1 |
| Okada, D; Shibuki, K | 1 |
| Breese, KR; Heistad, DD; Lopez, JA; Mügge, A; Piegors, DJ | 1 |
| Chester, AH; Moncada, S; O'Neil, GS; Palmer, RM; Tadjkarimi, S; Yacoub, MH | 1 |
| Hodson, HF; Moncada, S; Palmer, RM; Rees, DD; Schulz, R | 1 |
| Brain, SD; Hughes, SR; Williams, TJ | 1 |
| Mills, CD | 1 |
| Jansson, L; Sandler, S | 1 |
| Feelisch, M; McCall, TB; Moncada, S; Palmer, RM | 1 |
| Mannaioni, PF; Masini, E; Pistelli, A; Salvemini, D; Vane, J | 1 |
| Bianchi, S; Gambassi, F; Lupini, M; Mannaioni, PF; Masini, E; Mugnai, L; Pistelli, A | 2 |
| Mannaioni, PF; Masini, E; Pistelli, A; Salvemini, D; Vane, JR | 1 |
| Allen, SP; Chester, AH; Khagani, A; Luu, TN; Musumeci, F; O'Neil, GS; Ridley, P; Tadjkarimi, S; Yacoub, MH | 1 |
| de Groot, H; Komarov, P; Sies, H; Wang, JF | 1 |
| Moncada, S; O'Connor, KJ | 1 |
| Holmes, L; Jenkins, DC; Moncada, S; Radomski, MW | 1 |
| Förster, S; Schrör, K; Woditsch, I | 2 |
| Whittle, BJ | 1 |
| Knowles, RG; Moncada, S; Palmer, RM; Venturini, CM | 1 |
| Bendtzen, K; Eizirik, DL; Sandler, S; Welsh, N | 1 |
| Braquet, P; Chabrier, PE; Demerlé-Pallardy, C; Lonchampt, MO | 1 |
| Madison, DV; Schuman, EM | 1 |
| de Graeff, PA; de Leeuw, MJ; Scholtens, E; van Gilst, WH; Wesseling, H | 1 |
| Gustafsson, LE; Leone, AM; Moncada, S; Persson, MG; Wiklund, NP | 1 |
| Murad, F; Schmidt, HH | 1 |
| Herbaczyńska-Cedro, K; Lembowicz, K; Pytel, B | 1 |
| Berkenboom, G; Fang, ZY; Fontaine, J; Goldman, M; Unger, P | 1 |
| Lewis, MJ; Moncada, S; Schulz, R; Smith, JA | 1 |
| Moncada, S; Palmer, RM; Smith, RE | 1 |
| Anggard, E; Mollace, V; Salvemini, D; Vane, J | 1 |
| Boulanger, CM; Lüscher, TF | 1 |
| Akabane, S; Ashida, T; Imanishi, M; Kawamura, M; Kawano, Y; Kinoshita, O; Kuramochi, M; Matsushima, Y; Yoshida, K; Yoshimi, H | 1 |
| Adnot, S; Braquet, P; Chabrier, PE; Eddahibi, S; Raffestin, B | 1 |
| Mollace, V; Salvemini, D; Vane, J | 1 |
| Fujiwara, S; Fukui, M; Iwaki, T; Kanaide, H; Moriguchi, M; Natori, Y; Takeshita, I | 1 |
| Esplugues, JV; Pique, JM; Whittle, BJ | 2 |
| Andersson, KE; Forman, A; Garcia Pascual, A; Persson, K; Tøttrup, A | 1 |
| Brewer, AS; Brockman, DE; Langdon, G; Myatt, L | 1 |
| Denham, S; Rowland, IJ | 1 |
| Chapelain, B; Jean, T; Néliat, G; Robert, R | 1 |
| Gavras, H; Gavras, I; Lammek, B; Wang, YX; Wierzba, T | 1 |
| Beierwaltes, WH; Carretero, OA | 1 |
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| Abacioğlu, N; Cakici, I; Kanzik, I; Ozmen, R; Tunçtan, B | 1 |
| Delles, C; Jacobi, J; John, S; Schlaich, MP; Schmieder, RE | 1 |
| Chen, Z; Jiao, Z; Kuang, Y; Wang, Q; Wu, Z; Yuan, J; Zeng, M; Zhou, H; Zhou, J | 1 |
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| Azuma, H; Masuda, H | 1 |
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| Azuma, H; Goto, M; Kihara, K; Masuda, H; Okuno, T; Tsujii, T | 1 |
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| Aso, T; Azuma, H; Goto, M; Momohara, Y; Obayashi, S; Sakamoto, S | 1 |
| Azuma, H; Kihara, K; Kurosaki, E; Masuda, H; Sakai, Y; Yamauchi, Y | 1 |
| Hayashida, Y; Morishita, T; Nakashima, Y; Nakata, S; Sasaguri, Y; Suda, O; Tasaki, H; Toyohira, Y; Tsujimoto, T; Tsutsui, M; Ueno, S; Ueta, Y; Yanagihara, N | 1 |
| Delles, C; Fleischmann, EF; Fleischmann, I; Oehmer, S; Schmieder, RE; Schneider, MP | 1 |
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| Clapp, BR; Hingorani, AD; Kharbanda, RK; MacAllister, RJ; Mohamed-Ali, V; Stephens, JW; Vallance, P | 1 |
| Felsen, D; Marion, D; Poppas, DP; Vaughan, ED | 1 |
| Brunini, T; Ellory, J; Mann, G; Meirelles, L; Mendes-Ribeiro, A; Moss, M; Rozentul, A; Siqueira, M; Soares de Moura, R | 1 |
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| Anthony, S; Leiper, J; Madhani, M; Malaki, M; McDonald, NQ; Murray-Rust, J; Nandi, M; O'Hara, B; Rossiter, S; Rudiger, A; Selwood, D; Smith, C; Stidwill, R; Torondel, B; Vallance, P; Wojciak-Stothard, B | 1 |
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| Hu, S; Qu, WZ; Sun, WY; Tu, W; Yu, ZF; Zhao, M | 1 |
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| Azuma, H; Hirata, Y; Imamura, M; Sakurada, M; Shichiri, M | 1 |
| Bralley, JA; Chirinos, JA; Chirinos-Pacheco, J; Corrales-Medina, F; Cuba-Bustinza, C; David, R; Medina-Lezama, J; Muñoz-Atahualpa, E; Zea-Díaz, H | 1 |
| Bernan, VS; Carter, GT; Feng, X; Haltli, B; He, H; Ratnayake, AS; Singh, MP | 1 |
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| Al-Zobaidy, MJ; Craig, J; Martin, W | 1 |
| Cui, Y; Gao, CQ; Guan, C; Qu, F; Sun, G; Tang, C; Yu, F; Zhou, Y | 1 |
| Jung, CS | 1 |
| Adams, MR; Celermajer, DS; Ilsar, R; Kritharides, L; Levitt, J; Ng, MK | 1 |
| Cerrato, R; Grönros, J; Jung, C; Lundberg, JO; Ostenson, CG; Pernow, J | 1 |
| Atzler, D; Bache, RJ; Böger, RH; Chen, Y; Fassett, J; Guo, H; Hu, X; Lu, Z; Schwedhelm, E; Xu, X; Zhang, P | 1 |
| Kirch, W; Leuschner, S; Schindler, C; Schwanebeck, U | 1 |
| Chandna, S; Seth, RK; Suman, S | 1 |
| Cooke, JP; Ghebremariam, YT | 1 |
| Akahoshi, A; Kitamatsu, M; Ohtsuki, T; Sisido, M; Suzue, Y | 1 |
| Al-Zobaidy, MJ; Brown, K; Craig, J; Martin, W; Pettifor, G | 1 |
| Barbosa, JB; Brunini, TM; Mann, GE; Matsuura, C; Mendes-Ribeiro, AC; Moraes, TL; Moss, MB; Neto, ML; Siqueira, MA | 1 |
| Caplin, B; Leiper, J | 1 |
| Cherney, DZ; Scholey, JW; Sochett, EB | 1 |
| Linz, TH; Lunte, SM | 1 |
| Bode-Böger, SM; Bódis, J; Hantosi, E; Kovács, GL; Martens-Lobenhoffer, J; Molnár, G; Sulyok, E; Tamás, P | 1 |
| Ally, A; Maher, TJ; Phattanarudee, S; Towiwat, P | 1 |
| Kobzar, G; Mardla, V; Samel, N | 1 |
| Kittel, A; Maas, R | 1 |
| Chen, B; Chicoine, LG; Cui, H; Jin, Y; Nelin, LD; Strauch, K | 1 |
| Akiyama, K; Fujii, K; Furuchi, T; Homma, H; Katane, M; Nonaka, S; Ozeki, Y; Saitoh, Y; Sekine, M; Shimoda, K; Tsunoda, M | 1 |
| Al-Zobaidy, MJ; Martin, W | 1 |
| Figulla, HR; Franz, M; Fritzenwanger, M; Jung, C; Lichtenauer, M; Pernow, J; Pfeifer, R; Pfeil, A; Quitter, F; Shemyakin, A | 1 |
| Betik, AC; Frugier, T; Hong, YH; Lynch, GS; McConell, GK; Murphy, RM; Rattigan, S; Zhang, X | 1 |
| Clement, B; Frankel, A; Lakowski, TM; Pak, ML; Szeitz, A; Thomas, D; Vhuiyan, MI | 1 |
| Chen, YS; He, J; Huang, HQ; Li, J; Li, ZL; Ouyang, LY; Ye, SB; Zeng, YX; Zhang, H; Zhang, XS | 1 |
| Appelbaum, S; Atzler, D; Bauer, C; Blankenberg, S; Böger, RH; Hoffmann, B; Lackner, KJ; Münzel, T; Ojeda, FM; Ramuschkat, M; Schnabel, RB; Schwedhelm, E; Sinning, CR; Wild, PS; Zeller, T | 1 |
| Cherkanova, MS; Gilinsky, MA; Sukhovershin, RA | 1 |
| Bazer, FW; Che, D; Hou, Y; Hu, S; Jia, S; Nawaratna, G; Wang, F; Wu, G | 1 |
| Chen, A; Chen, Y; Fassett, JT; Hou, L; Liu, X; Xu, D; Xu, Y; Yang, L; Zhuang, Y | 1 |
| Akiyama, K; Fujii, K; Homma, H; Katane, M; Miyamoto, T; Nonaka-Hashida, S; Ozeki, Y; Saitoh, Y; Sekine, M; Shimoda, K; Tsunoda, M | 1 |
| Karlsson, WK; Kruuse, C; Sørensen, CG | 1 |
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| Arós, F; Clish, CB; Corella, D; Estruch, R; Fitó, M; Gómez-Gracia, E; Guasch-Ferré, M; Hruby, A; Hu, FB; Lapetra, J; Liang, L; Martínez-González, MA; Romaguera, D; Ros, E; Ruiz-Canela, M; Salas-Salvadó, J; Serra-Majem, L; Toledo, E; Wang, DD; Yu, E | 1 |
| Jiao, PL; Li, JK; Liu, B; Sun, JC; Tan, X; Wang, WZ; Wang, YK; Wu, ZT | 1 |
| Böger, RH; Brito, J; De La Cruz, JJ; Hannemann, J; Ibanez, C; León-Velarde, F; Lüneburg, N; Siques, P | 1 |
| Ahmetaj-Shala, B; Gashaw, H; Gray, N; Kirkby, NS; Leiper, JM; MacCallum, N; Mitchell, JA; Mumby, S; Paul-Clark, M; Quinlan, GJ; Tesfai, A; Want, E | 1 |
| Bode-Böger, SM; Emrich, IE; Fliser, D; Heine, GH; Martens-Lobenhoffer, J; Wagenpfeil, S; Zawada, AM | 1 |
| Chen, Y; Liu, X; Shang, R; Xu, X | 1 |
| Arós, F; Bullo, M; Clish, C; Cofán, M; Corella, D; Dennis, C; Estruch, R; Fitó, M; Guasch-Ferré, M; Gutiérrez-Bedmar, M; Hu, FB; Lapetra, J; Liang, L; Martínez-González, MA; Papandreou, C; Razquin, C; Romaguera, D; Ros, E; Ruiz-Canela, M; Salas-Salvadó, J; Serra-Majem, L; Sorlí, JV; Toledo, E; Wang, DD; Yu, E | 1 |
| Abusoglu, G; Abusoglu, S; Avci, A; Demir, K; Eryavuz, D; Hosaf, M; Unlu, A | 1 |
| Driver, T; Edelson-Averbukh, M; Katsanovskaja, K; Pipkorn, R | 1 |
| Blood, AB; Borchardt, D; Ishtiaq Ahmed, AS; Li, Q; Liu, T; Mukosera, GT; Power, GG; Tipple, TE; Zhang, M | 1 |
| Gao, Y; Huang, H; Huang, M; Lv, W; Tang, H; Xiao, H | 1 |
| Berent, TE; Dorschner, JM; Jatoi, A; Kumar, R; Kunz, HE; Lanza, IR; Meyer, T; Wang, X | 1 |
| Alptekin, H; Karaman, S; Onmaz, DE; Sivrikaya, A | 1 |
| Deniz, S; Iritas, SB; Oztan, O; Turksoy, VA; Tutkun, E | 1 |
| Güney, Z; Günhan, M; Kurgan, Ş; Önder, C; Şengül, V; Serdar, MA | 1 |
| Aizawa, F; Hamada, H; Ishio-Ueoka, H; Kajiwara, T; Kamikawa, N; Kimura, T; Namba, H; Sato, YM; Sekikawa, K; Yoshida, T | 1 |
| Alibhai, J; Brown, JI; Frankel, A; Zhu, E | 1 |
| Doğan, Ö; Haşimi, A; Serdar, CC; Serdar, MA | 1 |
| Demirbas, N; Eryavuz Onmaz, D; Kutlu, R; Onmaz, M; Unlu, A | 1 |
| Antosiewicz, J; Borkowska, A; Juhas, U; Kortas, J; Pilis, K; Reczkowicz, J; Sobol, Z; Ziemann, E; Zychowska, M | 1 |
38 review(s) available for arginine and omega-n-methylarginine
| Article | Year |
|---|---|
Biosynthesis and role of the endothelium-derived vasodilator, nitric oxide, in the gastric mucosa.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Gastric Mucosa; Humans; Intestines; Microcirculation; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine | 1992 |
Overproduction of nitric oxide in cytokine-mediated and septic shock.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cytokines; Humans; Interleukin-2; Neoplasms; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Shock, Septic | 1992 |
Biosynthesis and actions of nitric oxide.
Topics: Animals; Arginine; Blood Platelets; Brain; Cytotoxicity, Immunologic; Endothelium, Vascular; Humans; Macrophages; Neutrophils; Nitric Oxide; omega-N-Methylarginine; Platelet Aggregation; Rabbits; Rats; Vasodilation | 1991 |
[Nitric oxide and sepsis].
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Bacterial Infections; Humans; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Shock, Septic | 1993 |
The biological and pharmacological role of nitric oxide in platelet function.
Topics: Amino Acid Oxidoreductases; Arginine; Arteriosclerosis; Blood Platelets; Endothelium, Vascular; Enzyme Induction; Guanylate Cyclase; Hemorrhage; Hemostasis; Humans; Iron-Sulfur Proteins; Isoenzymes; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Activation; Platelet Aggregation; Thrombosis; Vasodilation | 1993 |
Vascular biology: relevance of nitric oxide in vascular and nonvascular tissue with normal and decreased renal function.
Topics: Amino Acid Oxidoreductases; Arginine; Endothelium, Vascular; Enzyme Induction; Hemodynamics; Humans; Hypotension; Inflammation; Kidney Diseases; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Shock, Septic | 1994 |
Induction of superoxide anion and nitric oxide production in cultured microglia.
Topics: Animals; Animals, Newborn; Arginine; Cells, Cultured; Growth Hormone; Interferons; Interleukin-1; Kinetics; Lipopolysaccharides; Microglia; Nitric Oxide; omega-N-Methylarginine; Potassium; Rats; Superoxides; Tetradecanoylphorbol Acetate | 1994 |
Inhibition of nitric oxide synthase--potential for a novel class of therapeutic agent?
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Humans; Isoenzymes; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Recombinant Proteins | 1995 |
Use of nitric oxide synthase inhibitors as a novel treatment for septic shock.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Clinical Trials as Topic; Humans; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Shock, Septic | 1995 |
Role of nitric oxide in autoimmunity.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Autoimmune Diseases; Enzyme Inhibitors; Humans; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine | 1995 |
Nitric oxide: a novel mediator of inflammation.
Topics: Adenosine Diphosphate Ribose; Animals; Arginine; Arthritis, Experimental; Cell Survival; Endothelium, Vascular; Humans; Inflammation; Iron; Isoenzymes; Models, Biological; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Prostaglandins; Sulfhydryl Compounds | 1995 |
Role of nitric oxide in glomerular physiology and pathophysiology.
Topics: Amino Acids; Animals; Arginine; Humans; Kidney; Kidney Glomerulus; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine | 1995 |
Macrophage nitric oxide mediates immunosuppression in infectious inflammation.
Topics: Animals; Arginine; Bacterial Vaccines; Concanavalin A; Immune Tolerance; Inflammation; Lymphocytes; Macrophages; Mice; Nitric Oxide; omega-N-Methylarginine; Salmonella Infections, Animal; Salmonella typhimurium; Suppressor Factors, Immunologic | 1994 |
The measurement of nitric oxide release induced by kainic acid using a novel hemoglobin-trapping technique with microdialysis.
Topics: Animals; Arginine; Brain; Hemoglobins; Humans; Kainic Acid; Microdialysis; Nitric Oxide; omega-N-Methylarginine; Perfusion | 1994 |
Endothelial dysfunction in chronic heart failure. Experimental and clinical studies.
Topics: Arginine; Chronic Disease; Endothelium, Vascular; Heart Failure; Humans; In Vitro Techniques; Nitric Oxide; omega-N-Methylarginine | 1994 |
Selective inhibition of the activity of inducible nitric oxide synthase in septic shock.
Topics: Animals; Arginine; Disease Models, Animal; Enzyme Induction; Enzyme Inhibitors; Guanidines; Humans; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Shock, Septic; Thiourea | 1995 |
Role of nitric oxide in the vascular dysfunction of septic shock.
Topics: Animals; Arginine; Blood Vessels; Endotoxins; Enzyme Inhibitors; Humans; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Shock, Septic | 1995 |
Inhibitors of nitric oxide synthase and the opioid withdrawal syndrome.
Topics: Animals; Arginine; Morphine Dependence; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Substance Withdrawal Syndrome | 1995 |
Use of L-arginine and its analogs to study nitric oxide pathway in humans.
Topics: Arginine; Humans; Nitric Oxide; omega-N-Methylarginine; Signal Transduction | 1996 |
Design of nitric oxide synthase inhibitors and their use to reverse hypotension associated with cancer immunotherapy.
Topics: Animals; Arginine; Blood Pressure; Dogs; Drug Design; Enzyme Inhibitors; Humans; Hypotension; Immunotherapy; Interleukin-2; Neoplasms; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine | 1997 |
Renal endothelial function in humans.
Topics: Albuminuria; Arginine; Endothelium; Enzyme Inhibitors; Humans; Hypertension; Kidney; Nitric Oxide Synthase; omega-N-Methylarginine | 1998 |
Nitric oxide and arginine.
Topics: Amidohydrolases; Animals; Arginine; Enzyme Inhibitors; Humans; Hydrolases; Kinetics; Models, Chemical; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine | 1999 |
Endothelium-derived nitric oxide and vascular physiology and pathology.
Topics: Animals; Arginine; Arteriosclerosis; Blood Vessels; Caveolin 1; Caveolins; Cell Adhesion; Endothelium, Vascular; Enzyme Induction; Enzyme Inhibitors; Humans; Hypertension; Hypertension, Pulmonary; Isoenzymes; Membrane Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Oxidative Stress; Rabbits; Signal Transduction; Vascular Diseases; Vasodilation | 1999 |
Uremic bleeding: closing the circle after 30 years of controversies?
Topics: Anemia; Animals; Arginine; Bleeding Time; Blood Platelets; Endothelium, Vascular; Enzyme Inhibitors; Erythropoietin; Guanidines; Hemorrhage; History, 18th Century; History, 20th Century; Humans; Isoenzymes; Kidney Failure, Chronic; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Succinates; Uremia | 1999 |
Biological significance of endogenous methylarginines that inhibit nitric oxide synthases.
Topics: Amidohydrolases; Animals; Arginine; Cytosol; Enzyme Inhibitors; Humans; Hydrolases; Isoenzymes; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Protein-Arginine N-Methyltransferases | 1999 |
Endothelial function and nitric oxide: clinical relevance.
Topics: Arginine; Cardiovascular Diseases; Coronary Disease; Endothelium, Vascular; Genetic Therapy; Humans; Nitric Oxide; omega-N-Methylarginine; Risk Factors; Sepsis; Vasoconstriction | 2001 |
[Biological and pathophysiological roles of endogenous methylarginines as inhibitors of nitric oxide synthase].
Topics: Animals; Arginine; Nitric Oxide Synthase; omega-N-Methylarginine | 2002 |
Cardiovascular biology of the asymmetric dimethylarginine:dimethylarginine dimethylaminohydrolase pathway.
Topics: Amidohydrolases; Animals; Arginine; Cardiovascular Diseases; Cardiovascular Physiological Phenomena; Diabetes Mellitus; Endothelium, Vascular; Enzyme Inhibitors; Female; Humans; Mice; Models, Biological; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Pre-Eclampsia; Pregnancy; Protein-Arginine N-Methyltransferases; Renal Insufficiency | 2004 |
Nitric oxide pathway as new drug targets for refractory hypertension.
Topics: Animals; Antihypertensive Agents; Arginine; Blood Pressure; Endothelium, Vascular; Humans; Hypertension; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Signal Transduction; Superoxides | 2005 |
Endogenous production of nitric oxide synthase inhibitors.
Topics: Arginine; Enzyme Inhibitors; Humans; Isoenzymes; Nitric Oxide Synthase; omega-N-Methylarginine; Protein-Arginine N-Methyltransferases; Renal Insufficiency | 2005 |
Quantification of ADMA: analytical approaches.
Topics: Arginine; Chromatography, High Pressure Liquid; Chromatography, Liquid; Enzyme-Linked Immunosorbent Assay; Gas Chromatography-Mass Spectrometry; Humans; omega-N-Methylarginine; Reproducibility of Results | 2005 |
Chromatographic-mass spectrometric methods for the quantification of L-arginine and its methylated metabolites in biological fluids.
Topics: Animals; Arginine; Body Fluids; Chromatography, Liquid; Humans; Mass Spectrometry; omega-N-Methylarginine | 2007 |
The lung in the balance: arginine, methylated arginines, and nitric oxide.
Topics: Animals; Arginine; Humans; Lung; Methylation; Models, Biological; Nitric Oxide; omega-N-Methylarginine; Protein-Arginine N-Methyltransferases | 2007 |
Endogenous nitric oxide synthase inhibitors in the biology of disease: markers, mediators, and regulators?
Topics: Amidohydrolases; Animals; Arginine; Binding Sites; Binding, Competitive; Biomarkers; Cardiovascular Agents; Cardiovascular Diseases; Catalytic Domain; Enzyme Inhibitors; Humans; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine | 2012 |
Pharmacology and clinical pharmacology of methylarginines used as inhibitors of nitric oxide synthases.
Topics: Animals; Arginine; Enzyme Inhibitors; Humans; Nitric Oxide; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Structure-Activity Relationship | 2014 |
Effect of asymmetric dimethylarginine (ADMA) on heart failure development.
Topics: Amidohydrolases; Animals; Arginine; Heart Failure; Humans; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Peroxynitrous Acid; Signal Transduction; Superoxides | 2016 |
l-arginine and l-NMMA for assessing cerebral endothelial dysfunction in ischaemic cerebrovascular disease: A systematic review.
Topics: Arginine; CADASIL; Cerebrovascular Disorders; Clinical Trials as Topic; Endothelium, Vascular; Humans; omega-N-Methylarginine; Vasodilation | 2017 |
Asymmetric dimethylarginine (ADMA) as an important risk factor for the increased cardiovascular diseases and heart failure in chronic kidney disease.
Topics: Amidohydrolases; Animals; Arginine; Endothelium, Vascular; Heart Failure; Humans; Nitric Oxide Synthase; omega-N-Methylarginine; Renal Insufficiency, Chronic; Risk Factors; Signal Transduction | 2018 |
51 trial(s) available for arginine and omega-n-methylarginine
| Article | Year |
|---|---|
L-arginine-dependent reactive nitrogen intermediates and the antimicrobial effect of activated human mononuclear phagocytes.
Topics: Animals; Arginase; Arginine; Cells, Cultured; Chlamydophila psittaci; Female; Humans; Interferon-gamma; Leishmania donovani; Macrophages; Mice; Mice, Inbred BALB C; Monocytes; Nitrogen; omega-N-Methylarginine; Toxoplasma | 1992 |
Different interactions of platelets with arterial and venous coronary bypass vessels.
Topics: Apyrase; Arginine; Aspirin; Blood Platelets; Coronary Artery Bypass; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; In Vitro Techniques; Indomethacin; Isometric Contraction; Ketanserin; Mammary Arteries; Muscle, Smooth, Vascular; Norepinephrine; omega-N-Methylarginine; Platelet Aggregation; Saphenous Vein; Thromboxane A2 | 1991 |
Converting enzyme inhibitors and the role of the sulfhydryl group in the potentiation of exo- and endogenous nitrovasodilators.
Topics: Aged; Angina Pectoris; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Blood Pressure; Bradykinin; Captopril; Coronary Circulation; Cysteine; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Isosorbide Dinitrate; Male; Middle Aged; Nitric Oxide; Nitro Compounds; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Sulfhydryl Compounds; Vasodilator Agents | 1991 |
Effects of endothelium-derived nitric oxide on peripheral arteriolar tone in man.
Topics: Acetylcholine; Adult; Arginine; Brachial Artery; Dose-Response Relationship, Drug; Drug Evaluation; Endothelium, Vascular; Female; Forearm; Humans; Infusions, Intra-Arterial; Male; Muscle Tonus; Nitric Oxide; Nitroglycerin; omega-N-Methylarginine; Regional Blood Flow; Time Factors; Vasodilation | 1989 |
Effects of a nitric oxide synthase inhibitor in humans with septic shock.
Topics: Adult; Aged; Aged, 80 and over; Amino Acid Oxidoreductases; Arginine; Blood Pressure; Cardiac Output; Double-Blind Method; Female; Heart Rate; Humans; Infusions, Intravenous; Injections, Intravenous; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Shock, Septic; Vascular Resistance | 1994 |
Inhibition of nitric oxide synthesis increases blood pressure in healthy humans.
Topics: Adult; Amino Acid Oxidoreductases; Arginine; Blood Pressure; Hemodynamics; Humans; Infusions, Intravenous; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Single-Blind Method | 1993 |
No functional involvement of 5-hydroxytryptamine1A receptors in nitric oxide-dependent dilatation caused by serotonin in the human forearm vascular bed.
Topics: Adult; Arginine; Dose-Response Relationship, Drug; Forearm; Hemodynamics; Humans; Injections, Intra-Arterial; Male; Nitric Oxide; omega-N-Methylarginine; Piperazines; Plethysmography; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Regional Blood Flow; Serotonin; Serotonin Receptor Agonists; Vascular Resistance; Vasodilation | 1994 |
Effect of NG-monomethyl-L-arginine on kinin-induced vasodilation in the human forearm.
Topics: Adult; Analysis of Variance; Arginine; Brachial Artery; Bradykinin; Drug Interactions; Endothelium, Vascular; Forearm; Humans; Infusions, Intra-Arterial; Male; Nitric Oxide; omega-N-Methylarginine; Plethysmography; Regional Blood Flow; Substance P; Vasodilation | 1994 |
Contribution of nitric oxide to metabolic coronary vasodilation in the human heart.
Topics: Acetylcholine; Adenosine; Adult; Arginine; Cardiac Pacing, Artificial; Coronary Artery Disease; Coronary Circulation; Female; Humans; Male; Middle Aged; Myocardium; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Risk Factors; Vascular Resistance; Vasodilation | 1995 |
Effect of a nitric oxide synthase inhibitor and a glucocorticosteroid on exhaled nitric oxide.
Topics: Adult; Arginine; Asthma; Cross-Over Studies; Double-Blind Method; Enzyme Inhibitors; Female; Humans; Male; Nitric Oxide; omega-N-Methylarginine; Prednisolone; Respiration; Respiratory System | 1995 |
Inhibition of acetylcholinesterase selectively potentiates NG-monomethyl-L-arginine-resistant actions of acetylcholine in human forearm vasculature.
Topics: Acetylcholine; Adult; Arginine; Dose-Response Relationship, Drug; Drug Synergism; Edrophonium; Forearm; Humans; Kinetics; Methacholine Chloride; Middle Aged; Nitric Oxide; omega-N-Methylarginine; Regional Blood Flow; Vasodilation | 1995 |
Endothelium-derived relaxing factor is important in mediating the high output state in chronic severe anemia.
Topics: Adult; Anemia; Arginine; Cardiac Output, High; Chronic Disease; Dose-Response Relationship, Drug; Forearm; Hemodynamics; Humans; Male; Methacholine Chloride; Middle Aged; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Regional Blood Flow; Single-Blind Method; Vascular Resistance | 1995 |
NG-methyl-L-arginine, an inhibitor of nitric oxide synthase, reverses interleukin-2-induced hypotension.
Topics: Adult; Arginine; Carcinoma, Renal Cell; Drug Administration Schedule; Female; Hemodynamics; Humans; Hypotension; Interleukin-2; Male; Middle Aged; Nitric Oxide; omega-N-Methylarginine; Pilot Projects; Prospective Studies | 1995 |
Nitric oxide mediated venodilator effects of nebivolol.
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Arginine; Atenolol; Benzopyrans; Dinoprost; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Ethanolamines; Hand; Humans; Infusions, Intravenous; Male; Nebivolol; Nitric Oxide; Nitroglycerin; omega-N-Methylarginine; Vasodilation; Vasodilator Agents; Veins | 1994 |
Local L-NG-monomethyl-arginine attenuates the vasodilator action of bradykinin in the human forearm.
Topics: Adult; Arginine; Bradykinin; Dose-Response Relationship, Drug; Forearm; Humans; Male; Middle Aged; Nitric Oxide; Nitroglycerin; Norepinephrine; omega-N-Methylarginine; Regional Blood Flow; Vasodilation | 1994 |
The effect of antihypertensive therapy on responsiveness to local intra-arterial NG-monomethyl-L-arginine in patients with essential hypertension.
Topics: Amlodipine; Arginine; Blood Pressure; Double-Blind Method; Enalapril; Female; Forearm; Humans; Hypertension; Male; Middle Aged; omega-N-Methylarginine; Regional Blood Flow | 1994 |
Nitric oxide contributes to the rise in forearm blood flow during mental stress in humans.
Topics: Adolescent; Adult; Arginine; Atropine; Blood Flow Velocity; Female; Forearm; Humans; Male; Nitric Oxide; omega-N-Methylarginine; Regional Blood Flow; Stress, Psychological; Vasodilation | 1994 |
Impaired endothelium-dependent vasodilation in patients with essential hypertension. Evidence that nitric oxide abnormality is not localized to a single signal transduction pathway.
Topics: Acetylcholine; Adult; Arginine; Arm; Bradykinin; Female; Humans; Hypertension; Male; Middle Aged; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Regional Blood Flow; Signal Transduction; Vascular Resistance; Vasodilation | 1995 |
Effect of angiotensin-converting enzyme inhibitors on endothelium-dependent peripheral vasodilation in patients with chronic heart failure.
Topics: Acetylcholine; Arginine; Aspirin; Enalaprilat; Endothelium, Vascular; Female; Forearm; Heart Failure; Hemodynamics; Humans; Infusions, Intra-Arterial; Male; Middle Aged; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Peptidyl-Dipeptidase A; Plethysmography; Premedication; Vasodilation | 1994 |
[Increased vascular sensitivity to nitroglycerin in patients with hypercholesterolemia and peripheral endothelial dysfunction].
Topics: Acetylcholine; Arginine; Endothelium, Vascular; Female; Forearm; Humans; Hypercholesterolemia; Male; Microcirculation; Middle Aged; Nitric Acid; Nitric Oxide; Nitroglycerin; omega-N-Methylarginine; Radial Artery; Ultrasonography | 1994 |
L-NMMA increases blood pressure in man.
Topics: Arginine; Blood Pressure; Humans; Male; Nitric Oxide; omega-N-Methylarginine; Single-Blind Method | 1993 |
Dietary fish oil augments nitric oxide production or release in patients with type 2 (non-insulin-dependent) diabetes mellitus.
Topics: Acetylcholine; Arachidonic Acid; Arginine; Blood Glucose; Blood Platelets; Blood Pressure; Cell Membrane; Cholesterol; Diabetes Mellitus, Type 2; Dietary Fats; Docosahexaenoic Acids; Double-Blind Method; Eicosapentaenoic Acid; Female; Fish Oils; Forearm; Glycated Hemoglobin; Heart Rate; Hemodynamics; Humans; Male; Membrane Lipids; Middle Aged; Nitric Oxide; Olive Oil; omega-N-Methylarginine; Plant Oils; Triglycerides; Vascular Resistance | 1993 |
Endothelium-dependent modulation of responses to endothelin-I in human veins.
Topics: Adult; Arginine; Aspirin; Drug Synergism; Endothelins; Endothelium, Vascular; Epoprostenol; Humans; Male; Nitric Oxide; Nitroglycerin; omega-N-Methylarginine; Vasoconstriction | 1993 |
Influence of basal nitric oxide secretion on cardiac function in man.
Topics: Adult; Arginine; Double-Blind Method; Endothelins; Enzyme Inhibitors; Heart; Hemodynamics; Humans; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Placebos; Reference Values | 1995 |
Retention of endothelium-dependent properties in human mammary arteries after cryopreservation.
Topics: 6-Ketoprostaglandin F1 alpha; Acetylcholine; Analysis of Variance; Anti-Bacterial Agents; Arginine; Cryopreservation; Dose-Response Relationship, Drug; Endothelins; Endothelium, Vascular; Humans; In Vitro Techniques; Mammary Arteries; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Norepinephrine; omega-N-Methylarginine; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 1996 |
Relationship between sympathetic nervous system activity, baroreflex and cardiovascular effects after acute nitric oxide synthesis inhibition in humans.
Topics: Adult; Arginine; Baroreflex; Cardiovascular Physiological Phenomena; Cardiovascular System; Catecholamines; Echocardiography; Enzyme Inhibitors; Hemodynamics; Humans; Male; Nitric Oxide; omega-N-Methylarginine; Sympathetic Nervous System | 1995 |
Inhibitors of nitric oxide synthase in human skin.
Topics: Adolescent; Adult; Arginine; Blood Vessels; Calcitonin Gene-Related Peptide; Dinoprostone; Enzyme Inhibitors; Erythema; Female; Hot Temperature; Humans; Male; Middle Aged; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Radiation Injuries; Reference Values; Regional Blood Flow; Skin; Ultraviolet Rays; Vasoconstriction | 1996 |
Randomised double-blind placebo-controlled study of the effect of inhibition of nitric oxide synthesis in bradykinin-induced asthma.
Topics: Adult; Aerosols; Arginine; Asthma; Bradykinin; Bronchial Provocation Tests; Cross-Over Studies; Double-Blind Method; Enzyme Inhibitors; Female; Humans; Lung Volume Measurements; Male; Methacholine Chloride; Middle Aged; Nitric Oxide Synthase; omega-N-Methylarginine | 1996 |
Effects of in vivo and in vitro L-arginine supplementation on healthy human vessels.
Topics: Acetylcholine; Adult; Arginine; Arteries; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Endothelium, Vascular; Forearm; Humans; Liver Function Tests; Male; omega-N-Methylarginine; Plethysmography; Vasoconstriction | 1996 |
Randomized, double-blind, placebo-controlled study of supplemental oral L-arginine in patients with heart failure.
Topics: Administration, Oral; Adult; Arginine; Cardiac Output, Low; Cross-Over Studies; Double-Blind Method; Female; Forearm; Humans; Male; Middle Aged; Nitric Oxide Synthase; omega-N-Methylarginine; Physical Exertion; Quality of Life; Regional Blood Flow; Vasoconstriction | 1996 |
Tetrahydrobiopterin restores endothelial function in hypercholesterolemia.
Topics: Adult; Antioxidants; Arginine; Biopterins; Endothelium; Female; Forearm; Humans; Hypercholesterolemia; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Plethysmography; Serotonin; Vasoconstriction; Vasodilation | 1997 |
Role of nitric oxide towards vasodilator effects of substance P and ATP in human forearm vessels.
Topics: Acetylcholine; Adenosine Triphosphate; Adolescent; Adult; Aged; Arginine; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Female; Forearm; Humans; Indomethacin; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Plethysmography; Regional Blood Flow; Substance P; Vasodilator Agents | 1997 |
Nitric oxide and ocular blood flow in patients with IDDM.
Topics: Adult; Arginine; Blood Flow Velocity; Cross-Over Studies; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Enzyme Inhibitors; Eye; Hemodynamics; Humans; Infusions, Intravenous; Lasers; Male; Microscopy, Interference; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Ophthalmic Artery; Pulsatile Flow; Time Factors | 1997 |
Effects of inhibition of the L-arginine/nitric oxide pathway on vasodilation caused by beta-adrenergic agonists in human forearm.
Topics: Adolescent; Adrenergic beta-Agonists; Adult; Albuterol; Arginine; Dobutamine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Forearm; Humans; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Vasodilation; Vasodilator Agents | 1997 |
Effects of short-term forearm exercise training on resistance vessel endothelial function in normal subjects and patients with heart failure.
Topics: Acetylcholine; Adult; Aged; Aged, 80 and over; Analysis of Variance; Arginine; Brachial Artery; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Exercise; Exercise Therapy; Female; Forearm; Hand Strength; Heart Failure; Humans; Infusions, Intra-Arterial; Male; Middle Aged; Muscle Contraction; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Plethysmography; Regional Blood Flow; Vascular Resistance; Vasodilation; Vasodilator Agents | 1998 |
Haemodynamic effects of inhibition of nitric oxide synthase and of L-arginine at rest and during exercise.
Topics: Adult; Arginine; Blood Pressure; Enzyme Inhibitors; Exercise; Humans; Male; Middle Aged; Nitric Oxide Synthase; omega-N-Methylarginine | 1998 |
Pharmacokinetic-pharmacodynamic profile of systemic nitric oxide-synthase inhibition with L-NMMA in humans.
Topics: Adult; Area Under Curve; Arginine; Blood Pressure; Breath Tests; Cardiac Output; Choroid; Drug Interactions; Enzyme Inhibitors; Fundus Oculi; Heart Rate; Hemodynamics; Humans; Infusions, Intravenous; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Pulsatile Flow; Time Factors | 1999 |
Acetazolamide-induced cerebral and ocular vasodilation in humans is independent of nitric oxide.
Topics: Acetazolamide; Adult; Arginine; Blood Vessels; Carbonic Anhydrase Inhibitors; Cerebrovascular Circulation; Cross-Over Studies; Double-Blind Method; Enzyme Inhibitors; Eye; Humans; Nitric Oxide; omega-N-Methylarginine; Vasodilation | 1999 |
Serum nitrite sensitively reflects endothelial NO formation in human forearm vasculature: evidence for biochemical assessment of the endothelial L-arginine-NO pathway.
Topics: Acetylcholine; Adult; Analysis of Variance; Arginine; Arteriosclerosis; Biomarkers; Endothelium, Vascular; Female; Forearm; Humans; Male; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Papaverine; Regional Blood Flow; Regression Analysis; Vasodilator Agents | 1999 |
Effects of some guanidino compounds on human cerebral arteries.
Topics: Adult; Aged; Arginine; Enzyme Inhibitors; Female; Guanidines; Humans; Male; Methylguanidine; Middle Aged; Middle Cerebral Artery; Nitric Oxide Synthase; omega-N-Methylarginine; Vasoconstrictor Agents; Vasodilator Agents | 1999 |
Endogenous nitric oxide in the regulation of gastric secretory and motor activity in humans.
Topics: Acetates; Adult; Arginine; Breath Tests; Cross-Over Studies; Drug Therapy, Combination; Food; Gastric Acid; Gastric Emptying; Gastrins; Hemodynamics; Humans; Hydrogen-Ion Concentration; Male; Manometry; Nitric Oxide; omega-N-Methylarginine; Placebos; Radioimmunoassay; Somatostatin; Time Factors | 1999 |
Nitric oxide synthesis inhibition does not impair water immersion-induced renal vasodilation in humans.
Topics: Adult; Arginine; Blood Pressure; Citrulline; Diuresis; Enzyme Inhibitors; Hormones; Humans; Immersion; Male; Natriuresis; Nitric Oxide; omega-N-Methylarginine; Renal Circulation; Vascular Resistance; Vasodilation; Water | 2000 |
Role of nitric oxide in the airway response to exercise in healthy and asthmatic subjects.
Topics: Administration, Inhalation; Adult; Arginine; Asthma, Exercise-Induced; Breath Tests; Cross-Over Studies; Double-Blind Method; Enzyme Inhibitors; Forced Expiratory Volume; Humans; Nitric Oxide; omega-N-Methylarginine; Time Factors | 2001 |
Interaction between cholinergic and nitrergic vasodilation: a novel mechanism of blood pressure control.
Topics: Adrenergic beta-Antagonists; Adult; Arginine; Atropine; Cardiac Output; Enzyme Inhibitors; Female; Hemodynamics; Humans; Leg; Male; Muscarinic Antagonists; Nitric Oxide Synthase; omega-N-Methylarginine; Phenylephrine; Propranolol; Regional Blood Flow; Statistics, Nonparametric; Vasoconstrictor Agents | 2001 |
Assessment of endothelial function of the renal vasculature in human subjects.
Topics: Adult; Arginine; Blood Pressure; Drug Interactions; Endothelium, Vascular; Enzyme Inhibitors; Glomerular Filtration Rate; Heart Rate; Humans; Kidney; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Renal Circulation | 2002 |
Effect of atorvastatin on endothelium-dependent vasodilation in postmenopausal women with average serum cholesterol levels.
Topics: Acetylcholine; Anticholesteremic Agents; Arginine; Atorvastatin; Brachial Artery; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cross-Over Studies; Double-Blind Method; Endothelium, Vascular; Female; Forearm; Heptanoic Acids; Humans; Hypercholesterolemia; Middle Aged; Nitroprusside; omega-N-Methylarginine; Postmenopause; Pyrroles; Reference Values; Regional Blood Flow; Treatment Outcome; Vasodilation; Vasodilator Agents | 2002 |
beta-Adrenoceptor-mediated, nitric-oxide-dependent vasodilatation is abnormal in early hypertension: restoration by L-arginine.
Topics: Acetylcholine; Adult; Arginine; Drug Synergism; Enzyme Inhibitors; Forearm; Humans; Hypertension; Isoproterenol; Male; Medical Records; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Plethysmography; Receptors, Adrenergic, beta; Regional Blood Flow; Vasodilation; Vasodilator Agents | 2004 |
Inflammation-induced endothelial dysfunction involves reduced nitric oxide bioavailability and increased oxidant stress.
Topics: Adult; Albuminuria; Analysis of Variance; Arginine; Ascorbic Acid; Biological Availability; Bradykinin; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Forearm; Humans; Male; Nitric Oxide; Nitroglycerin; Norepinephrine; omega-N-Methylarginine; Oxidative Stress; Plethysmography; Regional Blood Flow; Statistics, Nonparametric; Typhoid-Paratyphoid Vaccines; Vasoconstrictor Agents; Vasodilator Agents | 2004 |
Effects of nitric oxide synthase inhibition and L-arginine on renal haemodynamics in young patients at high cardiovascular risk.
Topics: Adult; Antioxidants; Arginine; Ascorbic Acid; Humans; Hypercholesterolemia; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Oxidative Stress; Renal Plasma Flow; Substrate Specificity | 2007 |
Regulation of alveolar gas conductance by NO in man, as based on studies with NO donors and inhibitors of NO production.
Topics: Adult; Arginine; Blood Pressure; Breath Tests; Carbon Monoxide; Enzyme Inhibitors; Humans; Lung Volume Measurements; Male; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; omega-N-Methylarginine; Pharmaceutical Vehicles; Pulmonary Circulation; Pulmonary Diffusing Capacity; Pulmonary Gas Exchange; Vascular Resistance; Young Adult | 2009 |
Characterization of local vascular effects of the nitric oxide inhibitor NG-monomethyl-L-arginine on dorsal hand veins.
Topics: Adult; Arginine; Autacoids; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Resistance; Endothelium, Vascular; Enzyme Inhibitors; Hand; Humans; Infusions, Intravenous; Male; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Stereoisomerism; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents; Veins; Young Adult | 2012 |
1840 other study(ies) available for arginine and omega-n-methylarginine
| Article | Year |
|---|---|
Inhibition of human dimethylarginine dimethylaminohydrolase-1 by S-nitroso-L-homocysteine and hydrogen peroxide. Analysis, quantification, and implications for hyperhomocysteinemia.
Topics: Amidohydrolases; Amino Acid Sequence; Animals; Binding Sites; Cloning, Molecular; Cysteine; Dose-Response Relationship, Drug; Drug Design; Homocysteine; Humans; Hydrogen Peroxide; Hyperhomocysteinemia; Kinetics; Molecular Sequence Data; Oxidation-Reduction; Sequence Homology, Amino Acid; Substrate Specificity | 2007 |
Role of lipoxygenase and cytochrome P-450 in production of endothelium-derived relaxing factors in canine femoral veins.
Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arginine; Benzoquinones; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dogs; Femoral Vein; In Vitro Techniques; Lipoxygenase Inhibitors; Masoprocol; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Piperidines; Proadifen | 1992 |
Induction of calcium-independent nitric oxide synthase activity in primary rat glial cultures.
Topics: Amino Acid Oxidoreductases; Animals; Animals, Newborn; Arginine; Astrocytes; Calcium; Cell Membrane; Cells, Cultured; Cerebral Cortex; Cytosol; Dactinomycin; Enzyme Induction; Kinetics; Lipopolysaccharides; Neurons; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Recombinant Proteins; Substrate Specificity; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1992 |
Actions of nitric oxide on the acute gastrointestinal damage induced by PAF in the rat.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Capillary Permeability; Endotoxins; Escherichia coli; Intestine, Small; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Penicillamine; Platelet Activating Factor; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Stomach; Vasodilator Agents | 1992 |
Studies on NG-methylarginine derivatives in myelin basic protein from developing and mutant mouse brain.
Topics: Animals; Arginine; Brain; Chromatography, High Pressure Liquid; Humans; Immunoblotting; Methylation; Mice; Mice, Mutant Strains; Myelin Basic Protein; Myelin Sheath; o-Phthalaldehyde; omega-N-Methylarginine; Rabbits; Rats; Structure-Activity Relationship | 1992 |
Generation of superoxide by purified brain nitric oxide synthase.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Brain; Cell Line; Chromatography, Affinity; Electron Spin Resonance Spectroscopy; Kidney; Kinetics; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Recombinant Proteins; Superoxides; Transfection | 1992 |
Co-purification of 130 kD nitric oxide synthase and a 22 kD link protein from human neutrophils.
Topics: Amino Acid Oxidoreductases; Arginine; Calcium; Chromatography, Affinity; Chromatography, Ion Exchange; Cytosol; Electrophoresis, Polyacrylamide Gel; Extracellular Matrix Proteins; Humans; Kinetics; Molecular Weight; NAD; Neutrophils; Nitric Oxide Synthase; omega-N-Methylarginine; Oxidation-Reduction; Proteins; Proteoglycans; Tetradecanoylphorbol Acetate | 1992 |
Arginase is a major pathway of L-arginine metabolism in nephritic glomeruli.
Topics: Amino Acid Oxidoreductases; Animals; Arginase; Arginine; Glomerulonephritis; In Vitro Techniques; Interferon-gamma; Kidney Glomerulus; Macrophages; Male; Nitric Oxide Synthase; omega-N-Methylarginine; Peritoneal Cavity; Rats; Rats, Inbred Lew | 1992 |
Nitric oxide mediates norepinephrine-induced prostaglandin E2 release from the hypothalamus.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Dinoprostone; Hemoglobins; Hypothalamus; In Vitro Techniques; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Norepinephrine; omega-N-Methylarginine; Rats | 1992 |
Inhibitors of nitric oxide synthase selectively reduce flow in tumor-associated neovasculature.
Topics: Adenocarcinoma; Amino Acid Oxidoreductases; Animals; Arginine; Colonic Neoplasms; Male; Melanoma, Experimental; Methylene Blue; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neoplasm Transplantation; Neoplasms, Experimental; Neovascularization, Pathologic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Prostheses and Implants; Regional Blood Flow | 1992 |
Protective effects of inhibitors of nitric oxide synthase in immune complex-induced vasculitis.
Topics: Alveolitis, Extrinsic Allergic; Amino Acid Oxidoreductases; Animals; Arginine; Immune Complex Diseases; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Ornithine; Peroxidase; Rats; Vasculitis, Leukocytoclastic, Cutaneous | 1992 |
Endothelium-dependent vasodilation is augmented by angiotensin converting enzyme inhibitors in healthy volunteers.
Topics: Acetylcholine; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Arginine; Aspirin; Drug Synergism; Enalaprilat; Endothelium, Vascular; Female; Forearm; Humans; Infusions, Intra-Arterial; Male; Middle Aged; Nitroprusside; omega-N-Methylarginine; Regional Blood Flow; Vascular Resistance; Vasodilation | 1992 |
Endothelium-dependent contraction produced by acetylcholine and relaxation produced by histamine in monkey basilar arteries.
Topics: Acetylcholine; Animals; Arachidonic Acid; Arginine; Basilar Artery; Dinoprost; Endothelium, Vascular; Female; Histamine; In Vitro Techniques; Macaca; Male; Methylene Blue; Muscle, Smooth, Vascular; omega-N-Methylarginine; Vasoconstriction; Vasodilation | 1992 |
The role of nitric oxide in endotoxic shock: effects of NG-monomethyl-L-arginine.
Topics: Alanine Transaminase; Animals; Arginine; Blood Pressure; Dexamethasone; Lipopolysaccharides; Male; Nitrates; Nitric Oxide; Nitrites; omega-N-Methylarginine; Penicillamine; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Shock, Septic | 1992 |
Involvement of nitric oxide in tumor cell adhesion to cytokine-activated endothelial cells.
Topics: Arginine; Cell Adhesion; Cell Adhesion Molecules; Cell Line; Cycloheximide; Cytokines; Dexamethasone; E-Selectin; Endothelium, Vascular; Humans; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Tumor Cells, Cultured | 1992 |
Endothelium-derived relaxing factor modulates renal interstitial cyclic GMP.
Topics: Animals; Arginine; Cyclic GMP; Dogs; Extracellular Space; Female; Kidney; Nitric Oxide; omega-N-Methylarginine; Renal Dialysis | 1992 |
Effects of endothelin-1 and inhibition of nitric oxide production with NG-monomethyl-L-arginine on arterial pressure and regional blood flow in anesthetized rats.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Dose-Response Relationship, Drug; Endothelins; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Wistar; Regional Blood Flow; Vascular Resistance; Vasoconstriction | 1992 |
Aprotinin inhibits platelet adhesion to endothelial cells.
Topics: Aprotinin; Arginine; Aspirin; Cells, Cultured; Collagen; Depression, Chemical; Endothelium, Vascular; Hirudins; Humans; Infant, Newborn; Nitric Oxide; omega-N-Methylarginine; Plastics; Platelet Adhesiveness; Thrombin; Umbilical Veins | 1992 |
Endothelium-derived relaxing factor inhibits platelet adhesion to cultured porcine endocardial endothelium.
Topics: Animals; Arginine; Cells, Cultured; Endocardium; Endothelium; Hemoglobins; Humans; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Platelet Adhesiveness; Substance P; Superoxide Dismutase; Swine | 1992 |
Effects of nitric oxide synthase inhibitors on gastric alkaline secretion in rats.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Bicarbonates; Gastric Acid; Gastric Mucosa; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Omeprazole; Rats; Rats, Sprague-Dawley | 1992 |
Inhibition of nitric oxide synthesis improves survival in a murine peritonitis model of sepsis that is not cured by antibiotics alone.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cilastatin; Cilastatin, Imipenem Drug Combination; Disease Models, Animal; Drug Combinations; Drug Therapy, Combination; Escherichia coli Infections; Imipenem; Male; Mice; Nitric Oxide Synthase; omega-N-Methylarginine; Peritonitis | 1992 |
Reversal of hypotension induced by Vibrio vulnificus lipopolysaccharide in the rat by inhibition of nitric oxide synthase.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Heart Rate; Hypotension; Lipopolysaccharides; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Vibrio | 1992 |
Nitric oxide as a signal in thyroid.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Calcimycin; Calcium; Carbachol; Cyclic GMP; Dogs; Enzyme Activation; Guanylate Cyclase; Methylene Blue; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Receptors, Muscarinic; Signal Transduction; Thyroid Gland | 1992 |
Effects of trigeminal neurotransmitters on piglet pial arterioles.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arginine; Arterioles; Brain; Calcitonin Gene-Related Peptide; Dinoprostone; Indomethacin; Neurokinin A; Nitric Oxide; omega-N-Methylarginine; Pia Mater; Substance P; Swine; Trigeminal Nerve | 1992 |
Differences in the K(+)-channels opened by cromakalim, acetylcholine and substance P in rat aorta and porcine coronary artery.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Benzopyrans; Coronary Vessels; Cromakalim; Endothelium, Vascular; Glyburide; Male; omega-N-Methylarginine; Potassium; Potassium Channels; Pyrroles; Rats; Rats, Sprague-Dawley; Substance P; Swine | 1991 |
Role of basal release of nitric oxide on coronary flow and mechanical performance of the isolated rat heart.
Topics: Animals; Arginine; Cardiac Output; Coronary Circulation; Dose-Response Relationship, Drug; In Vitro Techniques; Lactates; Male; Myocardial Contraction; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred WKY | 1992 |
Metabolism of glyceryl trinitrate to nitric oxide by endothelial cells and smooth muscle cells and its induction by Escherichia coli lipopolysaccharide.
Topics: Animals; Arginine; Blood Pressure; Cattle; Cells, Cultured; Cyclic GMP; Cycloheximide; Endothelium, Vascular; Escherichia coli; Hemodynamics; Humans; In Vitro Techniques; Lipopolysaccharides; Muscle, Smooth, Vascular; Nitric Oxide; Nitrites; Nitroglycerin; omega-N-Methylarginine; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats | 1992 |
Interaction of non-arginine compounds with the endothelium-derived relaxing factor inhibitor, NG-monomethyl L-arginine.
Topics: Amiloride; Animals; Aorta; Arginine; Bucladesine; Citrulline; Drug Interactions; In Vitro Techniques; Male; Methylene Blue; Nitric Oxide; omega-N-Methylarginine; Phenylephrine; Rats; Rats, Inbred Strains; Superoxide Dismutase; Vasodilation; Vasodilator Agents | 1992 |
Pressure natriuresis in rats during blockade of the L-arginine/nitric oxide pathway.
Topics: Animals; Arginine; Blood Pressure; Cyclic GMP; Heart Rate; Male; Natriuresis; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Renin; Sodium | 1992 |
Association between synthesis and release of cGMP and nitric oxide biosynthesis by hepatocytes.
Topics: Animals; Arginine; Atrial Natriuretic Factor; Corynebacterium Infections; Cyclic GMP; Cytokines; Lipopolysaccharides; Liver; Nitric Oxide; Nitrous Oxide; omega-N-Methylarginine; Propionibacterium acnes | 1992 |
Detection of nitric oxide production in lipopolysaccharide-treated rats by ESR using carbon monoxide hemoglobin.
Topics: Animals; Arginine; Carboxyhemoglobin; Electron Spin Resonance Spectroscopy; Endothelium, Vascular; Escherichia coli; Hemoglobins; Hemolysis; Humans; Lipopolysaccharides; Macrophages; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains | 1992 |
Nitric oxide alters renal function and guanosine 3',5'-cyclic monophosphate.
Topics: Animals; Arginine; Cyclic GMP; Dialysis; Dogs; Extracellular Space; Female; Hemodynamics; Injections; Kidney; Nitric Oxide; omega-N-Methylarginine; Renal Circulation | 1992 |
Endothelium-dependent relaxation of rabbit middle cerebral artery to a histamine H3-agonist is reduced by inhibitors of nitric oxide and prostacyclin synthesis.
Topics: Animals; Arginine; Cerebral Arteries; Dexamethasone; Endothelium, Vascular; Epoprostenol; In Vitro Techniques; Indomethacin; Methylhistamines; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Rabbits; Receptors, Histamine; Receptors, Histamine H3; Tranylcypromine; Vasodilator Agents | 1992 |
Macrophage cytotoxicity against Entamoeba histolytica trophozoites is mediated by nitric oxide from L-arginine.
Topics: Animals; Arginase; Arginine; Cytotoxicity, Immunologic; Entamoeba histolytica; Hydrogen Peroxide; Iron; Macrophage Activation; Macrophages; Mice; Mice, Inbred BALB C; Nitric Oxide; omega-N-Methylarginine; Superoxides | 1992 |
Interaction between microvascular alpha 1- and alpha 2-adrenoceptors and endothelium-derived relaxing factor.
Topics: Animals; Arginine; Blood Vessels; Male; Microcirculation; Muscles; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vasoconstriction | 1992 |
Increases in NO2-/NO3- excretion in the urine as an indicator of the release of endothelium-derived relaxing factor during elevation of blood pressure.
Topics: Animals; Aorta, Thoracic; Arginine; Blood Pressure; Constriction; Male; Nitrates; Nitric Oxide; Nitrites; omega-N-Methylarginine; Rats; Rats, Inbred WKY; Time Factors | 1992 |
Methylations of 70,000-Da heat shock proteins in 3T3 cells: alterations by arsenite treatment, by different stages of growth and by virus transformation.
Topics: 3T3 Cells; Animals; Arginine; Arsenic; Arsenites; Avian Sarcoma Viruses; Cell Division; Cell Transformation, Viral; Chromatography, Ion Exchange; Electrophoresis, Gel, Two-Dimensional; Heat-Shock Proteins; Lysine; Methionine; Methylation; Mice; Molecular Weight; omega-N-Methylarginine | 1992 |
Effects of L-NG-monomethyl arginine on the cyclic GMP formations in rat mesenteric arteries.
Topics: Animals; Arginine; Cyclic GMP; Male; Mesenteric Arteries; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains | 1992 |
Involvement of the nitric oxide-cyclic GMP pathway in the desensitization of bradykinin responses of cultured rat sensory neurons.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Arginine; Binding, Competitive; Bradykinin; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Drug Synergism; Drug Tolerance; Electric Conductivity; Ganglia, Spinal; Neurons, Afferent; Nitric Oxide; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Rats | 1992 |
L-arginine-dependent killing of intracellular Ehrlichia risticii by macrophages treated with gamma interferon.
Topics: Animals; Arginine; Cyclic GMP; Deferoxamine; Ehrlichia; Female; Interferon-gamma; Macrophages; Mice; Nitric Oxide; Nitrites; Nitroprusside; omega-N-Methylarginine | 1992 |
Modulation of vascular tone by endothelin-1: role of preload, endothelial integrity and concentration of endothelin-1.
Topics: Animals; Aorta; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Endothelins; In Vitro Techniques; Indomethacin; Muscle, Smooth, Vascular; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Oxyhemoglobins; Rats; Rats, Inbred Strains; Vasoconstriction; Vasodilation | 1992 |
Role of endothelium in hypoxia-induced contraction of isolated rat pulmonary artery.
Topics: Animals; Arginine; Cyclic GMP; Endothelium, Vascular; Hypoxia; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; omega-N-Methylarginine; Pulmonary Artery; Rats | 1992 |
Both tumor necrosis factor and nitric oxide participate in lysis of simian virus 40-transformed cells by activated macrophages.
Topics: Animals; Arginine; Cell Transformation, Viral; Cells, Cultured; Cytotoxicity, Immunologic; Immunity, Cellular; In Vitro Techniques; Iron; Macrophage Activation; Macrophages; Mice; Nitric Oxide; omega-N-Methylarginine; Simian virus 40; Tumor Necrosis Factor-alpha | 1992 |
Endothelium-dependent inhibition of Na(+)-K+ ATPase activity in rabbit aorta by hyperglycemia. Possible role of endothelium-derived nitric oxide.
Topics: Animals; Aorta; Arginine; Diabetes Mellitus, Experimental; Endothelium, Vascular; Hyperglycemia; Male; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Osmolar Concentration; Rabbits; Rubidium Radioisotopes; Sodium-Potassium-Exchanging ATPase | 1992 |
Cultured astrocytoma cells generate a nitric oxide-like factor from endogenous L-arginine and glyceryl trinitrate: effect of E. coli lipopolysaccharide.
Topics: Arginine; Astrocytoma; Cyclic GMP; Escherichia coli; Humans; Indomethacin; Lipopolysaccharides; Nitric Oxide; Nitroglycerin; omega-N-Methylarginine; Platelet Aggregation; Tumor Cells, Cultured | 1992 |
Evidence for normal nitric oxide-mediated vasodilator tone in conscious rats with cirrhosis.
Topics: Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Hemodynamics; Liver Cirrhosis, Experimental; Male; Nitric Oxide; omega-N-Methylarginine; Osmolar Concentration; Rats; Rats, Sprague-Dawley; Reference Values; Vasodilation | 1992 |
Effect of local intra-arterial NG-monomethyl-L-arginine in patients with hypertension: the nitric oxide dilator mechanism appears abnormal.
Topics: Adult; Age Factors; Aged; Arginine; Blood Pressure; Dose-Response Relationship, Drug; Female; Forearm; Humans; Hypertension; Male; Middle Aged; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Reference Values; Regional Blood Flow; Vasodilation | 1992 |
Inhibition of nitric oxide synthesis during endotoxemia promotes intrahepatic thrombosis and an oxygen radical-mediated hepatic injury.
Topics: Animals; Arginine; Budd-Chiari Syndrome; Chemical and Drug Induced Liver Injury; Endotoxins; Female; Free Radical Scavengers; Free Radicals; Gram-Positive Bacterial Infections; Lipopolysaccharides; Liver; Liver Diseases; Macrophages; Mice; Mice, Inbred BALB C; Necrosis; Nitric Oxide; omega-N-Methylarginine; Oxygen; Phagocytes; Propionibacterium acnes; Superoxides; Toxemia | 1992 |
Involvement of nitric oxide in growth hormone (GH)-releasing hormone-induced GH secretion in rat pituitary cells.
Topics: Animals; Arginine; Cells, Cultured; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Growth Hormone; Growth Hormone-Releasing Hormone; Hemoglobins; Male; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Pituitary Gland, Anterior; Potassium; Radioimmunoassay; Rats; Rats, Wistar | 1992 |
Analgesia by direct antagonism of nociceptor sensitization involves the arginine-nitric oxide-cGMP pathway.
Topics: Acyclic Monoterpenes; Analgesics; Animals; Arginine; Bucladesine; Cyclic AMP; Cyclic GMP; Dipyrone; Male; Monoterpenes; Nitric Oxide; Nociceptors; omega-N-Methylarginine; Phthalazines; Rats; Rats, Wistar; Terpenes | 1992 |
Activation of human macrophages for the killing of intracellular Trypanosoma cruzi by TNF-alpha and IFN-gamma through a nitric oxide-dependent mechanism.
Topics: Animals; Arginine; Cells, Cultured; Drug Synergism; Humans; Interferon-gamma; Macrophage Activation; Macrophages; Nitric Oxide; omega-N-Methylarginine; Recombinant Proteins; Superoxides; Trypanosoma cruzi; Tumor Necrosis Factor-alpha | 1992 |
Chemiluminescence of human bloodstream monocytes and neutrophils: an unusual oxidant(s) generated by monocytes during the respiratory burst.
Topics: Acridines; Arginine; Humans; Hydrogen Peroxide; In Vitro Techniques; Kinetics; Luminescent Measurements; Luminol; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; omega-N-Methylarginine; Oxidants; Peroxidase; Superoxides; Tetradecanoylphorbol Acetate | 1992 |
Characterization of noradrenaline-stimulated cyclic GMP formation in brain astrocytes in culture.
Topics: Animals; Arginine; Astrocytes; Brain; Calcium; Cells, Cultured; Cyclic GMP; Hemoglobins; In Vitro Techniques; Norepinephrine; omega-N-Methylarginine; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Sympatholytics; Sympathomimetics; Virulence Factors, Bordetella | 1992 |
[Nitrogen oxide is not an agent of endothelium-mediated arterial dilatation to an increase in the blood flow rate].
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Arginine; Blood Flow Velocity; Blood Pressure; Cats; Dose-Response Relationship, Drug; Drug Interactions; Endothelium, Vascular; Femoral Artery; Nitroarginine; Nitrogen Oxides; omega-N-Methylarginine; Vasodilation | 1992 |
Interleukin 1 beta induces the formation of nitric oxide by beta-cells purified from rodent islets of Langerhans. Evidence for the beta-cell as a source and site of action of nitric oxide.
Topics: Aconitate Hydratase; Animals; Arginine; Cyclic GMP; Cycloheximide; Electron Spin Resonance Spectroscopy; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Interleukin-1; Islets of Langerhans; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Secretory Rate; Tumor Cells, Cultured | 1992 |
Role of nitric oxide and guanosine 3',5'-cyclic monophosphate in mediating nonadrenergic, noncholinergic relaxation in guinea-pig pulmonary arteries.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Arginine; Autonomic Nervous System; Cyclic GMP; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Oxidopamine; Phosphodiesterase Inhibitors; Purinones; Pyrogallol; Sympathectomy, Chemical | 1992 |
Effect of acute plasma volume expansion on peripheral arteriolar tone in healthy subjects.
Topics: Arginine; Arterioles; Forearm; Humans; Norepinephrine; omega-N-Methylarginine; Plasma Volume; Plethysmography; Regional Blood Flow; Sodium Chloride; Vasodilation | 1992 |
NG-methyl-L-arginine decreases contractility, cGMP and cAMP in isoproterenol-stimulated rat hearts in vitro.
Topics: Animals; Arginine; Coronary Circulation; Cyclic AMP; Cyclic GMP; Heart; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardium; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley | 1992 |
Oxygen-mediated regulation of neonatal and adult rabbit aortic tension.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aging; Animals; Aorta; Arginine; Endothelium, Vascular; Enzyme Activation; In Vitro Techniques; Isoquinolines; Muscle Contraction; Muscle Development; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Oxygen; Piperazines; Potassium Chloride; Protein Kinase C; Rabbits | 1992 |
Inhibition of NO synthesis in septic shock.
Topics: Arginine; Hemodynamics; Humans; Nitric Oxide; omega-N-Methylarginine; Shock, Septic | 1992 |
Inhibition of NO synthesis in septic shock.
Topics: Adult; Arginine; Hemodynamics; Humans; Male; omega-N-Methylarginine; Shock, Septic | 1992 |
Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure.
Topics: Adult; Animals; Aorta; Arginine; Blood Pressure; Cells, Cultured; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Forearm; Guinea Pigs; Humans; Kidney Failure, Chronic; Male; Middle Aged; Nitric Oxide; omega-N-Methylarginine; Rats; Reference Values; Regional Blood Flow | 1992 |
NO inhibitors and septic shock.
Topics: Animals; Arginine; Humans; Nitric Oxide; omega-N-Methylarginine; Rats; Shock, Septic | 1992 |
Sympathetic modulation of endothelium-derived relaxing factor.
Topics: Adrenergic beta-Antagonists; Animals; Arginine; Blood Pressure; Decerebrate State; Ganglionic Blockers; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Sympathetic Nervous System | 1992 |
NG-monomethyl-L-arginine and nitroarginine potentiate pressor responsiveness of vasoconstrictors in conscious rats.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta; Arginine; Blood Pressure; Cyclic GMP; Drug Synergism; Female; NG-Nitroarginine Methyl Ester; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Renin-Angiotensin System; Vasoconstrictor Agents | 1992 |
Endothelial role in ouabain-induced contractions in guinea pig carotid arteries.
Topics: Adrenergic alpha-Antagonists; Animals; Arginine; Biological Assay; Carotid Arteries; Endothelium, Vascular; Female; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; omega-N-Methylarginine; Ouabain; Perfusion; Reserpine; Rubidium; Vasoconstriction | 1992 |
Biphasic 24-hour variations in cyclic GMP accumulation in the rat pineal gland are due to corresponding changes in the activity of cytosolic and particulate guanylate cyclase.
Topics: Animals; Arginine; Circadian Rhythm; Cyclic GMP; Cytosol; Enzyme Activation; Guanylate Cyclase; Male; Nitric Oxide; omega-N-Methylarginine; Pineal Gland; Rats; Rats, Sprague-Dawley; Time Factors | 1992 |
Relaxation of sheep cerebral arteries by vasoactive intestinal polypeptide and neurogenic stimulation: inhibition by L-NG-monomethyl arginine in endothelium-denuded vessels.
Topics: Animals; Arginine; Calcitonin Gene-Related Peptide; Cerebral Arteries; Electric Stimulation; Endothelium, Vascular; Immunohistochemistry; In Vitro Techniques; Nitric Oxide; omega-N-Methylarginine; Sheep; Vasoactive Intestinal Peptide; Vasodilation | 1991 |
Antagonists of nitric oxide synthesis inhibit nerve-mediated relaxations of longitudinal muscle in guinea pig ileum.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Guinea Pigs; Ileum; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth; Myenteric Plexus; Neurotransmitter Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Oxyhemoglobins; Papaverine | 1992 |
Formation of nitric oxide hemoglobin in erythrocytes co-cultured with alveolar macrophages taken from bleomycin treated rats.
Topics: Animals; Arginine; Bleomycin; Cell Communication; Cells, Cultured; Erythrocytes; Hemoglobins; Inflammation; Leukemia L1210; Macrophages, Alveolar; Male; Mice; Nitric Oxide; Nitrites; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Spectrophotometry | 1992 |
Insulin secretion from pancreatic B cells caused by L-arginine-derived nitrogen oxides.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Calcium; Calmodulin; Cell Line; Cyclic GMP; Enzyme Activation; Glucose; Guanylate Cyclase; Insulin; Insulin Secretion; Islets of Langerhans; NADP; Nitric Oxide Synthase; Nitroarginine; Nitrogen Oxides; omega-N-Methylarginine; Rats | 1992 |
Ca2+/calmodulin-dependent formation of hydrogen peroxide by brain nitric oxide synthase.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Binding, Competitive; Biopterins; Brain; Calcium; Calmodulin; Citrulline; Hydrogen Peroxide; NADP; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Swine | 1992 |
Different receptors mediate stimulation of nitric oxide-dependent cyclic GMP formation in neurons and astrocytes in culture.
Topics: Amino Acid Oxidoreductases; Animals; Animals, Newborn; Arginine; Astrocytes; Brain; Calcimycin; Carbachol; Catecholamines; Cells, Cultured; Cyclic GMP; Embryo, Mammalian; Glutamates; Histamine; Hormones; Ionomycin; Kinetics; Neurons; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Receptors, Cell Surface | 1992 |
Nitric oxide but not prostacyclin is an autocrine endothelial mediator.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arginine; Calcimycin; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Dinoprostone; Endothelium, Vascular; Epoprostenol; Iloprost; Nitric Oxide; omega-N-Methylarginine; Second Messenger Systems; Swine | 1992 |
Induction of nitric oxide synthase activity by toxic shock syndrome toxin 1 in a macrophage-monocyte cell line.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Bacterial Toxins; Cell Line; Cytosol; Enterotoxins; Enzyme Induction; Hydrocortisone; Indomethacin; Kinetics; Macrophages; Methylene Blue; Monocytes; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Oxyhemoglobins; Salicylates; Salicylic Acid; Staphylococcus aureus; Stereoisomerism; Superantigens; Superoxide Dismutase | 1992 |
Evidence that nitric oxide production by in vivo allosensitized cells inhibits the development of allospecific CTL.
Topics: Animals; Antigen-Antibody Reactions; Arginine; Cell Count; Cells, Cultured; Epitopes; Isoantigens; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred ACI; Rats, Inbred BN; Rats, Inbred Lew; Spleen; T-Lymphocytes, Cytotoxic; Transplantation, Homologous | 1992 |
Differential distribution of nitric oxide synthase between cell fractions isolated from the rat gastric mucosa.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Separation; Centrifugation, Density Gradient; Epithelial Cells; Epithelium; Gastric Mucosa; Kinetics; Nitric Oxide Synthase; omega-N-Methylarginine; Parietal Cells, Gastric; Povidone; Rats; Silicon Dioxide | 1992 |
Lung injury after deposition of IgA immune complexes. Requirements for CD18 and L-arginine.
Topics: Animals; Antigen-Antibody Complex; Antigens, CD; Arginine; Bronchoalveolar Lavage Fluid; CD18 Antigens; Cell Adhesion Molecules; E-Selectin; Immunoglobulin A; Lung Diseases; Macrophage-1 Antigen; Male; Mice; Mice, Inbred BALB C; Nitric Oxide; omega-N-Methylarginine; Rats; Tumor Necrosis Factor-alpha | 1992 |
Induction of nitric oxide synthase is a necessary precondition for expression of tumor necrosis factor-independent tumoricidal activity by activated macrophages.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Bone Marrow; Cell Line; Cell Survival; Cells, Cultured; Citrulline; Drug Resistance; Enterococcus faecalis; Escherichia coli; Kinetics; Lipopolysaccharides; Macrophage Activation; Macrophages; Male; Mast-Cell Sarcoma; Moraxella catarrhalis; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Onium Compounds; Peptidoglycan; Phagocytes; Rats; Rats, Inbred Strains; Tumor Necrosis Factor-alpha | 1992 |
Aminoguanidine, a novel inhibitor of nitric oxide formation, prevents diabetic vascular dysfunction.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Blood Vessels; Cells, Cultured; Diabetic Angiopathies; Enzyme Activation; Glucose; Guanidines; Insulin; Interleukin-1; Islets of Langerhans; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Regional Blood Flow | 1992 |
Stimulation of the nitric oxide synthase pathway in human hepatocytes by cytokines and endotoxin.
Topics: Amino Acid Oxidoreductases; Arginine; Cyclic GMP; Cytokines; Endotoxins; Humans; Lipopolysaccharides; Liver; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Recombinant Proteins | 1992 |
Nitric oxide synthase inhibitors cause sustained, but reversible, hypertension and hindquarters vasoconstriction in Brattleboro rats.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Hemodynamics; Hindlimb; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Brattleboro; Vasoconstrictor Agents | 1992 |
A central nervous system action of nitric oxide in blood pressure regulation.
Topics: Animals; Arginine; Blood Pressure; Central Nervous System; Heart Rate; Male; Nitric Oxide; omega-N-Methylarginine; Pressoreceptors; Rats; Rats, Inbred Strains; RNA | 1992 |
Nitric oxide mediates the vascular actions of cytokines in septic shock.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cytokines; Humans; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Shock, Septic; Vasodilation | 1992 |
Endothelial cGMP does not regulate basal release of endothelium-derived relaxing factor in culture.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Atrial Natriuretic Factor; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Vasodilator Agents | 1992 |
Identification and characterization of a calmodulin-dependent nitric oxide synthase from GH3 pituitary cells.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Autoradiography; Biopterins; Blotting, Western; Brain; Calmodulin; Cattle; Cells, Cultured; Chromatography, DEAE-Cellulose; Citrulline; Enzyme Activation; Kinetics; NADH Dehydrogenase; Nitric Oxide Synthase; Nitroarginine; Nitroblue Tetrazolium; omega-N-Methylarginine; Pituitary Gland | 1992 |
Differential role of endothelial function on vasodilator responses in series-arranged arterioles.
Topics: Acetylcholine; Animals; Arginine; Arterioles; Cheek; Cricetinae; Dextrans; Endothelium, Vascular; Female; Fluorescein-5-isothiocyanate; Mesocricetus; Nitric Oxide; omega-N-Methylarginine; Vasodilation; Video Recording | 1992 |
Evidence for reactive nitrogen intermediates in killing of staphylococci by human neutrophil cytoplasts. A new microbicidal pathway for polymorphonuclear leukocytes.
Topics: Amino Acid Oxidoreductases; Arginine; Blood Bactericidal Activity; Cell-Free System; Granulomatous Disease, Chronic; Humans; In Vitro Techniques; Neutrophils; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phagocytosis; Staphylococcus aureus | 1992 |
Lipopolysaccharide and cytokines induce a macrophage-type of nitric oxide synthase in bovine retinal pigmented epithelial cells.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cattle; Cycloheximide; Dexamethasone; Enzyme Induction; Interferon-gamma; Interleukin-1; Kinetics; Lipopolysaccharides; Macrophages; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Pigment Epithelium of Eye; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1992 |
Identification of inhibitors of nitric oxide synthase that do not interact with the endothelial cell L-arginine transporter.
Topics: Amino Acid Oxidoreductases; Amino Acid Transport Systems; Animals; Arginine; Biological Transport, Active; Carrier Proteins; Cells, Cultured; Endothelium, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Ornithine | 1992 |
Characterization of the receptor mediating relaxation to substance P in canine middle cerebral artery: no evidence for involvement of substance P in neurogenically mediated relaxation.
Topics: Animals; Arginine; Capsaicin; Cerebral Arteries; Dogs; Electric Stimulation; Endothelium, Vascular; In Vitro Techniques; omega-N-Methylarginine; Peptide Fragments; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P; Synaptic Transmission; Vasodilation | 1992 |
Endothelium-dependent relaxation to acetylcholine in the rabbit basilar artery: importance of membrane hyperpolarization.
Topics: Acetylcholine; Amino Acid Oxidoreductases; Animals; Arginine; Atropine; Basilar Artery; Carbachol; Endothelium, Vascular; Female; Male; Membrane Potentials; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rabbits; Receptors, Muscarinic | 1992 |
Cytotoxic activity and production of toxic nitrogen oxides by macrophages treated with IFN-gamma and monoclonal antibodies against the 73-kDa lipopolysaccharide receptor.
Topics: Animals; Arginine; Cytotoxicity, Immunologic; Histocompatibility Antigens Class II; Hot Temperature; Immunity, Cellular; Interferon-gamma; Lipopolysaccharide Receptors; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred C3H; Nitrogen Oxides; omega-N-Methylarginine; Polymyxin B; Receptors, Immunologic; Recombinant Proteins | 1992 |
Evidence for nitric oxide synthase inhibitor-sensitive and insensitive hippocampal synaptic potentiation.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Oxidoreductases; Animals; Arginine; Conditioning, Psychological; Evoked Potentials; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Inbred F344; Synapses | 1992 |
The non specificity of specific nitric oxide synthase inhibitors.
Topics: Amino Acid Oxidoreductases; Arginine; Cytochrome c Group; Epinephrine; Fatty Acids, Unsaturated; Ferrous Compounds; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Oxidation-Reduction | 1992 |
Characterization and localization of nitric oxide synthase in non-adrenergic non-cholinergic nerves from bovine retractor penis muscles.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blotting, Western; Calmodulin; Cattle; Cyclic GMP; Immunohistochemistry; Male; Nerve Tissue; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Penis | 1992 |
Segmental vascular responses to voltage-gated calcium channel potentiation in rat lung.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Arginine; Blood Pressure; Calcium; Calcium Channels; Histamine; In Vitro Techniques; Indomethacin; Ion Channel Gating; Lung; omega-N-Methylarginine; Potassium; Rats; Rats, Sprague-Dawley; Vasoconstriction | 1992 |
NMDA-induced release of nitric oxide potentiates aspartate overflow from cerebellar slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arginine; Aspartic Acid; Cerebellum; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Magnesium; N-Methylaspartate; Nitric Oxide; omega-N-Methylarginine; Quisqualic Acid; Rats; Rats, Wistar | 1992 |
Nitric oxide and cyclic GMP formation induced by interleukin 1 beta in islets of Langerhans. Evidence for an effector role of nitric oxide in islet dysfunction.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Biological Transport; Cyclic GMP; Cycloheximide; Glucose; Interleukin-1; Islets of Langerhans; Male; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Oxidation-Reduction; Rats; Rats, Sprague-Dawley | 1992 |
Glucocorticoids do not affect the induction of a novel calcium-dependent nitric oxide synthase in rabbit chondrocytes.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Calcium; Calmodulin; Cartilage, Articular; Cells, Cultured; Cycloheximide; Dexamethasone; Egtazic Acid; Enzyme Induction; Hydrocortisone; Indomethacin; Interleukin-1; Kinetics; Male; Nitric Oxide Synthase; omega-N-Methylarginine; Rabbits; Sulfonamides; Trifluoperazine | 1992 |
Inhibition of nitric oxide synthase protects against hypoxic neuronal injury.
Topics: Amino Acid Oxidoreductases; Animals; Arginase; Arginine; Cell Hypoxia; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Isomerism; Kinetics; Male; Neurons; Nitric Oxide Synthase; omega-N-Methylarginine; Pyramidal Tracts; Rats; Rats, Wistar; Synapses | 1992 |
Thimerosal blocks stimulated but not basal release of endothelium-derived relaxing factor (EDRF) in dog isolated coronary artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arachidonic Acid; Arginine; Arteries; Bradykinin; Calcimycin; Coronary Vessels; Dogs; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Prostaglandin Endoperoxides, Synthetic; Substance P; Thimerosal; Vasoconstrictor Agents | 1992 |
Endothelium-accelerated hyporesponsiveness of norepinephrine-elicited contraction of rat aorta in the presence of bacterial lipopolysaccharide.
Topics: Amino Acid Oxidoreductases; Animals; Aorta; Arginine; Argininosuccinic Acid; Dactinomycin; Endothelium, Vascular; Escherichia coli; In Vitro Techniques; Lipopolysaccharides; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Norepinephrine; omega-N-Methylarginine; Polymyxin B; Puromycin; Rabbits; Rats; Rats, Sprague-Dawley; Vasoconstriction | 1992 |
Soybean trypsin inhibitor and beta-amylase induce alveolar macrophages to release nitrogen oxides.
Topics: Animals; Arginine; beta-Amylase; Cells, Cultured; Dexamethasone; Dose-Response Relationship, Drug; Hypoxanthines; Limulus Test; Macrophages, Alveolar; Male; Nitrites; Nitrogen Oxides; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Time Factors; Trypsin Inhibitors | 1992 |
Developmental changes in endothelium-dependent pulmonary vasodilatation in pigs.
Topics: Acetylcholine; Aging; Animals; Animals, Newborn; Arginine; Dinoprost; Endothelium, Vascular; In Vitro Techniques; Masoprocol; Microscopy, Electron; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nitroprusside; omega-N-Methylarginine; Pulmonary Artery; Swine; Vasodilation | 1992 |
The role of induction of nitric oxide synthesis in the altered responses of jugular veins from endotoxaemic rabbits.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Arginine; Bacterial Toxins; Endotoxins; Enterotoxins; Female; In Vitro Techniques; Jugular Veins; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Prostaglandin Endoperoxides, Synthetic; Rabbits; Salmonella typhi; Vasoconstrictor Agents | 1992 |
The microbicidal activity of interferon-gamma-treated macrophages against Trypanosoma cruzi involves an L-arginine-dependent, nitrogen oxide-mediated mechanism inhibitable by interleukin-10 and transforming growth factor-beta.
Topics: Animals; Arginine; Cell Line; Female; Interferon-gamma; Interleukin-10; Macrophage Activation; Macrophages; Mice; Mice, Inbred C57BL; Nitric Oxide; omega-N-Methylarginine; Respiratory Burst; Transforming Growth Factor beta; Trypanosoma cruzi | 1992 |
Nitric oxide mediates suppression of T cell responses in murine Trypanosoma brucei infection.
Topics: Animals; Arginine; Concanavalin A; Immune Tolerance; Lymphocyte Activation; Mice; Mice, Inbred C3H; Nitric Oxide; Nitrites; omega-N-Methylarginine; Spleen; T-Lymphocytes; Trypanosoma brucei brucei; Trypanosomiasis, African | 1992 |
Endothelium-derived relaxing factor inhibition augments vascular angiotensin II reactivity in the pregnant rat hind limb.
Topics: Angiotensin II; Animals; Arginine; Blood Pressure; Blood Vessels; Female; Hindlimb; In Vitro Techniques; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Osmolar Concentration; Pregnancy; Pregnancy, Animal; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reference Values | 1992 |
Endothelium-dependent relaxation and noradrenaline sensitivity in mesenteric resistance arteries of streptozotocin-induced diabetic rats.
Topics: Acetylcholine; Animals; Arginine; Diabetes Mellitus, Experimental; Endothelium, Vascular; Female; Indomethacin; Mesenteric Arteries; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Norepinephrine; omega-N-Methylarginine; Rats | 1992 |
Comparison of the release of vasoactive factors from venous and arterial bovine cultured endothelial cells.
Topics: Amino Acids; Animals; Arachidonic Acid; Arginine; Bradykinin; Cattle; Cells, Cultured; Chromatography, High Pressure Liquid; Endothelins; Endothelium, Vascular; Epoprostenol; Fluorescence; Nitric Oxide; omega-N-Methylarginine; Radioimmunoassay | 1992 |
Nitric oxide does not mediate flow induced endothelium dependent arterial dilatation in the cat.
Topics: Acetylcholine; Animals; Arginine; Blood Pressure; Cats; Endothelium, Vascular; Female; Femoral Artery; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Regional Blood Flow; Vasodilation | 1992 |
Nitric oxide synthesis serves to reduce hepatic damage during acute murine endotoxemia.
Topics: Acute Disease; Animals; Arginine; Bacteremia; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Inflammation; Lipopolysaccharides; Liver Diseases; Liver Function Tests; Mice; Mice, Inbred BALB C; Nitric Oxide; omega-N-Methylarginine | 1992 |
Interferon-gamma induced lethality in the late phase of Plasmodium vinckei malaria despite effective parasite clearance by chloroquine.
Topics: Animals; Arginine; Chloroquine; Deferoxamine; Female; Immunization; Interferon-gamma; Liver; Malaria; Mice; Mice, Inbred BALB C; omega-N-Methylarginine; Pentoxifylline; Tumor Necrosis Factor-alpha | 1992 |
Distribution of free methylarginines in rat tissues and in the bovine brain.
Topics: Animals; Arginine; Brain Chemistry; Cattle; Intestines; Male; Myocardium; omega-N-Methylarginine; Rats; Rats, Wistar; Spleen; Testis; Tissue Distribution | 1992 |
Effects of nitric oxide-related compounds and carperitide on hemodynamics and hematocrit in anesthetized rats.
Topics: Anesthesia; Animals; Arginine; Atrial Natriuretic Factor; Blood Pressure; Erythrocytes; Heart Rate; Hematocrit; Hemodynamics; Male; Nitric Oxide; Nitroglycerin; Nitroprusside; omega-N-Methylarginine; Peptide Fragments; Rats; Rats, Wistar; Recombinant Proteins | 1992 |
Effects in cats of inhibition of nitric oxide synthesis on cerebral vasodilation and endothelium-derived relaxing factor from acetylcholine.
Topics: Acetylcholine; Animals; Arginine; Arterioles; Cats; Cerebrovascular Circulation; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Sodium Dodecyl Sulfate; Vasodilation | 1992 |
Nitric oxide mediates neurogenic relaxation induced in rabbit cavernous smooth muscle by electric field stimulation.
Topics: Animals; Arginine; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Penile Erection; Penis; Phenylephrine; Rabbits | 1992 |
NG-monomethyl-L-arginine causes nitric oxide synthesis in isolated arterial rings: trouble in paradise.
Topics: Animals; Aorta, Abdominal; Arginine; Calcimycin; Endothelium, Vascular; In Vitro Techniques; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Phenylephrine; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasodilation | 1992 |
Role of nitric oxide synthesis in the regulation of coronary vascular tone in the isolated perfused rabbit heart.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Arginine; Coronary Vessels; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroglycerin; omega-N-Methylarginine; Ornithine; Perfusion; Prostaglandin Endoperoxides, Synthetic; Rabbits; Vasoconstriction; Venous Pressure | 1992 |
Variable effects of human and canine polymorphonuclear leucocytes on vascular smooth muscle tone.
Topics: Animals; Arginine; Arteries; Chromones; Culture Techniques; Dogs; Endothelium; Humans; Indomethacin; Muscle Contraction; Muscle, Smooth, Vascular; Neutrophils; Nitric Oxide; omega-N-Methylarginine; Oxyhemoglobins; Prostaglandin Endoperoxides, Synthetic; Species Specificity; SRS-A; Superoxide Dismutase | 1992 |
Modulation of the hyperdynamic circulation of cirrhotic rats by nitric oxide inhibition.
Topics: Animals; Arginine; Blood Pressure; Hemodynamics; Liver Cirrhosis, Experimental; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Splanchnic Circulation | 1992 |
The arginine-dependent cytolytic mechanism plays a role in destruction of Naegleria fowleri amoebae by activated macrophages.
Topics: Animals; Arginine; Cytotoxicity, Immunologic; Female; Macrophage Activation; Macrophages; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Microscopy, Electron, Scanning; Naegleria fowleri; Nitric Oxide; omega-N-Methylarginine; Tumor Necrosis Factor-alpha | 1992 |
Cardiovascular actions of NG-methyl-L-arginine are abolished in a canine shock model using high-dose endotoxin.
Topics: Animals; Arginine; Blood Pressure; Cardiac Output; Disease Models, Animal; Dogs; Endotoxins; Escherichia coli; Heart; Hypotension; Lipopolysaccharides; Male; Nitric Oxide; omega-N-Methylarginine; Shock; Vascular Resistance; Vasoconstriction | 1992 |
Killing of Legionella pneumophila by nitric oxide in gamma-interferon-activated macrophages.
Topics: Animals; Arginine; Cell Line; Humans; Infant; Interferon-gamma; Iron; Legionella pneumophila; Leukemia, Promyelocytic, Acute; Macrophage Activation; Macrophages; Mice; Nitric Oxide; Nitrites; Nitroprusside; omega-N-Methylarginine; Recombinant Proteins; Tumor Cells, Cultured | 1992 |
Endothelium-dependent circulatory control--a mechanism for the differing peripheral vascular effects of isoflurane versus halothane.
Topics: Anesthesia, Inhalation; Animals; Arginine; Halothane; Hemodynamics; Isoflurane; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Wistar; Regional Blood Flow; Vascular Resistance | 1992 |
Effects of leukotrienes C4 and D4 on human isolated saphenous veins.
Topics: Arginine; Endothelium, Vascular; Humans; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth, Vascular; omega-N-Methylarginine; Saphenous Vein; SRS-A | 1992 |
Inhibition and stimulation of nitric oxide synthesis in the human forearm arterial bed of patients with insulin-dependent diabetes.
Topics: Acetylcholine; Adult; Arginine; Arm; Diabetes Mellitus, Type 1; Humans; Male; Nitric Oxide; Nitroprusside; Norepinephrine; omega-N-Methylarginine; Regional Blood Flow; Verapamil | 1992 |
Pregnancy reduces serotonin-induced contraction of guinea pig uterine and carotid arteries.
Topics: Animals; Arginine; Arteries; Carotid Arteries; Female; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Nitric Oxide; omega-N-Methylarginine; Potassium Chloride; Pregnancy; Pregnancy, Animal; Serotonin; Uterus; Vasoconstriction | 1992 |
Effect of endothelin-3 on cytosolic calcium level in vascular endothelium and on smooth muscle contraction.
Topics: Amino Acid Sequence; Animals; Aorta, Thoracic; Arginine; Calcium; Cytosol; Endothelin Receptor Antagonists; Endothelins; Endothelium, Vascular; In Vitro Techniques; Male; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; omega-N-Methylarginine; Peptide Fragments; Peptides, Cyclic; Rats; Rats, Wistar; Verapamil | 1992 |
TNF-alpha augments pulmonary vasoconstriction via the inhibition of nitrovasodilator activity.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Arginine; Capillary Resistance; Guinea Pigs; In Vitro Techniques; Meclofenamic Acid; Methylene Blue; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Prostaglandin Endoperoxides, Synthetic; Pulmonary Circulation; Pulmonary Wedge Pressure; Tumor Necrosis Factor-alpha; Vascular Resistance; Vasoconstriction; Vasodilation; Vasodilator Agents | 1992 |
Macrophage response to bacteria: induction of marked secretory and cellular activities by lipoteichoic acids.
Topics: Animals; Arginine; Cells, Cultured; Lipopolysaccharides; Macrophages; Male; Nitrogen Oxides; omega-N-Methylarginine; Rats; Structure-Activity Relationship; Teichoic Acids; Tumor Necrosis Factor-alpha | 1992 |
In vivo induction of nitrite and nitrate by tumor necrosis factor, lymphotoxin, and interleukin-1: possible roles in malaria.
Topics: Animals; Arginine; Female; Interleukin-1; Lymphotoxin-alpha; Malaria; Male; Mice; Mice, Inbred CBA; Nitrates; Nitric Oxide; Nitrites; omega-N-Methylarginine; Tumor Necrosis Factor-alpha | 1992 |
Nitric oxide production by monocytes in alcoholic liver disease.
Topics: Adult; Alcoholism; Arginine; Cells, Cultured; Female; Humans; Lipopolysaccharides; Liver Cirrhosis, Alcoholic; Male; Monocytes; Nitric Oxide; omega-N-Methylarginine; Reference Values | 1992 |
Recovery of endothelium-dependent responses by reseeding endothelial cells in culture onto the denuded coronary artery.
Topics: Animals; Arginine; Bradykinin; Calcimycin; Cells, Cultured; Coronary Vessels; Endothelium, Vascular; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Serotonin; Swine; Vasodilator Agents | 1992 |
Nitric oxide circulates in mammalian plasma primarily as an S-nitroso adduct of serum albumin.
Topics: Animals; Arginine; Blood Pressure; Luminescent Measurements; Nitric Oxide; Nitroso Compounds; omega-N-Methylarginine; Photolysis; Protein Binding; Rabbits; Serum Albumin | 1992 |
[Influences of hypercholesterolemia on the vessel function of isolated rat thoracic aorta].
Topics: Acetylcholine; Aging; Animals; Aorta, Thoracic; Arginine; Body Weight; Cholesterol, Dietary; Endothelium, Vascular; Hypercholesterolemia; In Vitro Techniques; Male; Muscle, Smooth, Vascular; omega-N-Methylarginine; Phenylephrine; Piperidines; Pyrimidinones; Rats; Rats, Inbred Strains; Vasoconstriction | 1992 |
The role of endothelium in the phenylephrine-induced oscillatory responses of rabbit mesenteric arteries.
Topics: Animals; Arginine; Autonomic Agents; Calcium; Cyclooxygenase Inhibitors; Endothelium, Vascular; Histamine Antagonists; Lipoxygenase Inhibitors; Male; Mesenteric Arteries; Methylene Blue; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Phenylephrine; Rabbits | 1992 |
Flow modulates coronary venular permeability by a nitric oxide-related mechanism.
Topics: Animals; Arginine; Capillary Permeability; Coronary Circulation; In Vitro Techniques; Nitric Oxide; omega-N-Methylarginine; Swine; Venules | 1992 |
Impaired endothelium-dependent and independent vasodilation in patients with type 2 (non-insulin-dependent) diabetes mellitus.
Topics: Acetylcholine; Analysis of Variance; Arginine; Diabetes Mellitus, Type 2; Endothelium, Vascular; Female; Forearm; Humans; Ischemia; Male; Middle Aged; Muscles; Nitroglycerin; omega-N-Methylarginine; Reference Values; Regional Blood Flow; Vasodilation | 1992 |
Protective and pathological roles of nitric oxide in endotoxin shock.
Topics: Animals; Arginine; Blood Pressure; Dexamethasone; Disease Models, Animal; Heart Rate; Male; Nitric Oxide; omega-N-Methylarginine; Penicillamine; Rabbits; Regional Blood Flow; S-Nitroso-N-Acetylpenicillamine; Shock, Septic | 1992 |
Endothelial modulation of the ouabain-induced contraction in human placental vessels.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Adult; Arginine; Arteries; Biological Assay; Blood Vessels; Endothelium, Vascular; Female; Humans; Indomethacin; Lipoxygenase Inhibitors; Muscle Contraction; omega-N-Methylarginine; Ouabain; Oxyhemoglobins; Placenta; Pyrazoles; Sodium; Vasoconstriction; Veins | 1992 |
Immunosuppression induced by nitric oxide and its inhibition by interleukin-4.
Topics: Animals; Antibodies, Monoclonal; Arginine; Female; Immune Tolerance; Immunization; Interferon-gamma; Interleukin-4; Macrophages; Mice; Mice, Inbred C3H; Nitric Oxide; omega-N-Methylarginine; Recombinant Proteins; Salmonella typhimurium; Spleen | 1992 |
Production of nitric oxide by murine bone marrow cells. Inverse correlation with cellular proliferation.
Topics: Animals; Arginine; Bone Marrow; Bone Marrow Cells; Canavanine; Cell Division; Cell Separation; Cells, Cultured; Granulocyte-Macrophage Colony-Stimulating Factor; In Vitro Techniques; Interferon-gamma; Interleukin-3; Lipopolysaccharides; Male; Mice; Mice, Inbred BALB C; Nitric Oxide; omega-N-Methylarginine; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1992 |
Inhibition of long-term potentiation by NMDA-mediated nitric oxide release.
Topics: Animals; Arginine; Electrophysiology; Hemoglobins; Hippocampus; In Vitro Techniques; N-Methylaspartate; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Rats; Time Factors | 1992 |
Role of nitric oxide in modulating permeability of hamster cheek pouch in response to adenosine 5'-diphosphate and bradykinin.
Topics: Adenosine Diphosphate; Animals; Arginine; Bradykinin; Capillary Permeability; Cheek; Cricetinae; Male; Mesocricetus; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine | 1992 |
Histamine receptors on human isolated pulmonary arterial muscle preparations: effects of endothelial cell removal and nitric oxide inhibitors.
Topics: Arginine; Burimamide; Chlorpheniramine; Cimetidine; Dimaprit; Endothelium, Vascular; Histamine; Humans; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Pulmonary Artery; Receptors, Histamine; Serotonin; Tetraethylammonium; Tetraethylammonium Compounds; Thiourea | 1992 |
Inhibition of renal nitric oxide synthesis with NG-monomethyl-L-arginine and NG-nitro-L-arginine.
Topics: Acetylcholine; Animals; Arginine; Atrial Natriuretic Factor; Dogs; Female; Kidney; Male; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Renal Circulation | 1992 |
NG-methyl-L-arginine, an inhibitor of L-arginine-derived nitric oxide synthesis, stimulates renal sympathetic nerve activity in vivo. A role for nitric oxide in the central regulation of sympathetic tone?
Topics: Animals; Arginine; Blood Pressure; Heart Rate; Homeostasis; Kidney; Male; Neural Conduction; Neural Inhibition; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Sympathetic Nervous System; Vagotomy | 1992 |
Acetylcholine increases pulmonary blood flow in intact fetuses via endothelium-dependent vasodilation.
Topics: Acetylcholine; Animals; Arginine; Endothelium, Vascular; Fetus; omega-N-Methylarginine; Pulmonary Circulation; Sheep; Vasodilation | 1992 |
Isoflurane produces endothelium-independent relaxation in canine middle cerebral arteries.
Topics: Animals; Arginine; Cerebral Arteries; Dogs; Endothelium, Vascular; Female; In Vitro Techniques; Isoflurane; Male; Muscle Relaxation; Muscle, Smooth, Vascular; omega-N-Methylarginine; Vasodilation | 1992 |
The effect of endothelium-derived nitric oxide on ex vivo whole blood platelet aggregation in man.
Topics: Acetylcholine; Adult; Arginine; Blood Flow Velocity; Endothelium, Vascular; Epoprostenol; Forearm; Humans; Infusions, Intra-Arterial; Male; Middle Aged; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Platelet Aggregation | 1992 |
Activated macrophages depress the contractility of rabbit carotids via an L-arginine/nitric oxide-dependent effector mechanism. Connection with amplified cytokine release.
Topics: Animals; Antioxidants; Arginine; Carotid Arteries; Cells, Cultured; Chromatography, High Pressure Liquid; Cytokines; Endothelium, Vascular; Interleukin-1; Lipopolysaccharides; Macrophage Activation; Macrophages; Male; Nitric Oxide; omega-N-Methylarginine; Rabbits; Tumor Necrosis Factor-alpha; Vasoconstriction | 1992 |
Cytotoxic action of IL-1 beta against pancreatic islets is mediated via nitric oxide formation and is inhibited by NG-monomethyl-L-arginine.
Topics: Animals; Arginine; Cells, Cultured; Interleukin-1; Islets of Langerhans; Male; Microscopy, Electron; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Lew | 1992 |
Nitric oxide-induced anti-mitogenic effects in high and low responder rat strains.
Topics: Animals; Arginine; Enterotoxins; Female; Interleukin-2; Lymphocyte Activation; Macrophages; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred BN; Rats, Inbred Lew; Species Specificity; T-Lymphocytes | 1992 |
Role of endothelium-derived relaxing factor in the in vivo renal vascular action of adenosine in dogs.
Topics: Acetylcholine; Adenosine; Animals; Arginine; Dogs; Female; Hemodynamics; Kidney; Male; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Phenethylamines; Renal Circulation; Theophylline | 1992 |
Effects of endothelium-derived nitric oxide on cerebral circulation during normoxia and hypoxia in the rat.
Topics: Acetylcholine; Animals; Arginine; Brain; Cerebrovascular Circulation; Endothelium, Vascular; Hypoxia; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Vascular Resistance; Xenon Radioisotopes | 1992 |
Production of nitrite by neonatal rat microglial cells/brain macrophages.
Topics: Animals; Animals, Newborn; Arginine; Brain; Cells, Cultured; Cytotoxicity, Immunologic; Interferon-gamma; Lipopolysaccharides; Macrophages; Nitric Oxide; Nitrites; omega-N-Methylarginine; Rats | 1992 |
Nitric oxide synthesis inhibitors attenuate calcitonin gene-related peptide endothelium-dependent vasorelaxation in rat aorta.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Calcitonin Gene-Related Peptide; Endothelium, Vascular; Ibuprofen; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Norepinephrine; omega-N-Methylarginine; Rats; Rats, Inbred Strains | 1992 |
Nitric oxide and angiotensin II. Glomerular and tubular interaction in the rat.
Topics: Angiotensin II; Animals; Arginine; Biphenyl Compounds; Glomerular Filtration Rate; Glycine; Imidazoles; Kidney Glomerulus; Kidney Tubules; Losartan; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Saralasin; Tetrazoles | 1992 |
Modulatory role of EDRF in hypoxic contraction of isolated porcine pulmonary arteries.
Topics: Acetylcholine; Animals; Arginine; Dose-Response Relationship, Drug; Endothelium, Vascular; Hypoxia; In Vitro Techniques; Methylene Blue; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Oxyhemoglobins; Phenylephrine; Pulmonary Artery; Swine | 1992 |
Intestinal lymphatic vessels release endothelial-dependent vasodilators.
Topics: Acetylcholine; Animals; Arginine; Arterioles; Bradykinin; Endothelium; Endothelium, Vascular; Ileum; Lymphatic System; Male; Muscle, Smooth; Muscle, Smooth, Vascular; omega-N-Methylarginine; Rats; Rats, Inbred Strains | 1992 |
Role of intracellular thiols in release of EDRF from cultured endothelial cells.
Topics: Adenosine Diphosphate; Animals; Aorta; Arginine; Biological Assay; Cattle; Cells, Cultured; Cysteine; Diamide; Endothelium, Vascular; Ethylmaleimide; Glutathione; Ionomycin; Kinetics; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Sulfhydryl Compounds; Sulfhydryl Reagents | 1992 |
T-cell mitogenic responses in fully xenogeneic chimeras (WF rat----B10 mouse) are restored by blocking the L-arginine-dependent nitric oxide pathway.
Topics: Animals; Arginine; Cells, Cultured; Chimera; Concanavalin A; Lymphocyte Activation; Mice; Mice, Inbred Strains; Nitric Oxide; omega-N-Methylarginine; Plant Lectins; Rats; Rats, Inbred Strains; T-Lymphocytes; Transplantation, Heterologous | 1992 |
Regulation of arteriolar tone and responses via L-arginine pathway in skeletal muscle.
Topics: Animals; Arginine; Arterioles; Bradykinin; Dose-Response Relationship, Drug; Indomethacin; Male; Muscles; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Vasomotor System | 1992 |
Role of nitric oxide in the control of basal hemodynamics.
Topics: Anesthesia; Animals; Arginine; Dose-Response Relationship, Drug; Hemodynamics; Nitric Oxide; omega-N-Methylarginine; Rats; Reference Values | 1992 |
Endothelium-dependent relaxation and L-arginine metabolism in genetic hypertension.
Topics: Animals; Arginine; Endothelium, Vascular; Female; Hypertension; Male; omega-N-Methylarginine; Phenylephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasodilation | 1992 |
Nitric oxide inactivates endothelium-derived contracting factor in the rat aorta.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Endothelium, Vascular; Free Radical Scavengers; Hypertension; Male; Methylene Blue; Nitric Oxide; omega-N-Methylarginine; Oxygen; Oxyhemoglobins; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Superoxide Dismutase | 1992 |
Does nitric oxide mediate the increases in cerebral blood flow elicited by hypercapnia?
Topics: Animals; Arginine; Brain; Hypercapnia; Male; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Papaverine; Rats; Rats, Inbred Strains; Regional Blood Flow | 1992 |
Inhibition of endothelium-derived relaxing factor enhances endothelin-mediated vasoconstriction.
Topics: Animals; Arginine; Dogs; Endothelins; Hemodynamics; Nitric Oxide; omega-N-Methylarginine; Vasoconstriction | 1992 |
Myogenic vascular regulation in skeletal muscle in vivo is not dependent of endothelium-derived nitric oxide.
Topics: Animals; Arginine; Capillaries; Cats; Muscle Tonus; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Physical Exertion; Regional Blood Flow; Vasodilation | 1992 |
Inhibition in the rat of nitric oxide synthesis in vivo does not attenuate the hypotensive action of acetylcholine, ATP or bradykinin.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Arginine; Bradykinin; Endothelium, Vascular; Glyburide; Hypotension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains | 1992 |
L-NMMA in brain microcirculation of mice is inhibited by blockade of cyclooxygenase and by superoxide dismutase.
Topics: Animals; Arginine; Aspirin; Blood Platelets; Cell Adhesion; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Free Radical Scavengers; Indomethacin; Male; Mice; Mice, Inbred ICR; Microcirculation; Nitroarginine; omega-N-Methylarginine; Platelet Aggregation; Superoxide Dismutase; Vasodilation; Vasodilator Agents | 1992 |
Inhibition of endothelium-derived relaxing factor-dependent circulatory control in intact rats.
Topics: Animals; Arginine; Blood Circulation; Blood Pressure; Hemodynamics; Male; Methylene Blue; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Rest; Vasodilator Agents | 1992 |
Endothelial L-arginine pathway and regional cerebral arterial reactivity to vasopressin.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arginine; Arginine Vasopressin; Brain Stem; Cerebral Arteries; Cerebrovascular Circulation; Dogs; Endothelium, Vascular; Female; Male; omega-N-Methylarginine; Prostaglandin Endoperoxides, Synthetic; Vasoconstrictor Agents; Vasopressins; Virulence Factors, Bordetella | 1992 |
Nitric oxide functions as an inhibitor of platelet adhesion under flow conditions.
Topics: Animals; Arginine; Blood Circulation; Cells, Cultured; Endothelium, Vascular; Humans; In Vitro Techniques; Nitric Oxide; omega-N-Methylarginine; Ornithine; Platelet Adhesiveness | 1992 |
Adenosine release in morphine-induced hypotension in rats.
Topics: 2-Chloroadenosine; Adenosine; Animals; Arginine; Blood Pressure; Dipyridamole; Hypotension; Injections, Intraperitoneal; Injections, Intravenous; Male; Morphine; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Tetrabenazine; Theophylline | 1992 |
Endothelin-3 is a potent pulmonary vasodilator in the rat.
Topics: Animals; Arginine; Blood Pressure; Endothelins; Hypoxia; In Vitro Techniques; Male; omega-N-Methylarginine; Perfusion; Pulmonary Artery; Pulmonary Circulation; Rats; Rats, Inbred Strains; Vasodilation; Vasodilator Agents | 1992 |
Endogenous nitric oxide and sensory neuropeptides interact in the modulation of the rat gastric microcirculation.
Topics: Animals; Arginine; Blood Pressure; Capsaicin; Gastric Mucosa; Indomethacin; Male; Microcirculation; Neurons, Afferent; Neuropeptides; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains | 1992 |
Effects of inhibiting nitric oxide biosynthesis on the systemic and splanchnic circulation of rats with portal hypertension.
Topics: Animals; Arginine; Blood Circulation; Constriction; Hypertension, Portal; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Reference Values; Splanchnic Circulation | 1992 |
Agonist-induced tension determines vascular reactivity during anoxia and reoxygenation.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Endothelins; Endothelium, Vascular; Epinephrine; Hypoxia; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; omega-N-Methylarginine; Oxygen; Potassium Chloride; Rats; Rats, Inbred Strains; Reperfusion; Vasoconstrictor Agents | 1992 |
Endothelial function in chronic congestive heart failure.
Topics: Acetylcholine; Adult; Arginine; Blood Flow Velocity; Brachial Artery; Chronic Disease; Endothelium, Vascular; Female; Forearm; Heart Failure; Humans; Male; Middle Aged; Muscle, Smooth, Vascular; Nitroglycerin; omega-N-Methylarginine; Radius; Regional Blood Flow; Ultrasonography; Vascular Resistance; Vasodilation; Vasomotor System | 1992 |
Endotoxin and TNF alpha directly stimulate nitric oxide formation in cultured rat hepatocytes from chronically endotoxemic rats.
Topics: Animals; Arginine; Cells, Cultured; Cycloheximide; Dactinomycin; Dexamethasone; Lipopolysaccharides; Liver; Nitric Oxide; omega-N-Methylarginine; Rats; Toxemia; Tumor Necrosis Factor-alpha | 1992 |
Actions of L- and D-arginine and NG-monomethyl-L-arginine on the blood pressure of pithed normotensive and spontaneously hypertensive rats.
Topics: Animals; Arginine; Blood Pressure; Decerebrate State; Hypertension; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Species Specificity; Stereoisomerism | 1992 |
Flow cytometric analysis of nitric oxide production in human neutrophils using dichlorofluorescein diacetate in the presence of a calmodulin inhibitor.
Topics: Arginine; Calmodulin; Flow Cytometry; Fluoresceins; Humans; Neutrophils; Nitric Oxide; omega-N-Methylarginine; Oxidation-Reduction; Solutions; Sulfonamides | 1992 |
Effect of N-substituted arginine compounds on blood pressure in anesthetized rats.
Topics: Amino Acids; Anesthesia; Animals; Arginine; Blood Pressure; Drug Interactions; Indomethacin; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains | 1992 |
Modulation of acute inflammation by endogenous nitric oxide.
Topics: Acute Disease; Animals; Arginine; Capillary Permeability; Carrageenan; Dexamethasone; Edema; Inflammation; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains | 1992 |
Effects of inhibition of nitric oxide formation on regional blood flow in experimental myocardial infarction.
Topics: Animals; Arginine; Blood Pressure; Coronary Circulation; Dipyridamole; Hemodynamics; Male; Myocardial Infarction; Nitric Oxide; Nitroglycerin; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Time Factors; Vascular Resistance | 1992 |
Protamine releases endothelium-derived relaxing factor from systemic arteries. A possible mechanism of hypotension during heparin neutralization.
Topics: Animals; Arginine; Arteries; Dogs; Endothelium, Vascular; Heparin; Hypotension; Nitric Oxide; omega-N-Methylarginine; Protamines; Stereoisomerism; Vasodilation | 1992 |
The endothelium-dependent effects of thimerosal on mouse pial arterioles in vivo: evidence for control of microvascular events by EDRF as well as prostaglandins.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arginine; Arterioles; Dinoprostone; Male; Mice; Nitric Oxide; omega-N-Methylarginine; Pia Mater; Thimerosal; Vasodilation | 1992 |
Evaluation of endothelium-derived nitric oxide mediated vasodilation utilizing ex vivo perfusion of an intact vessel.
Topics: Acetylcholine; Analysis of Variance; Animals; Arginine; Carotid Arteries; Dogs; Dose-Response Relationship, Drug; Endothelium, Vascular; Epinephrine; Nitric Oxide; omega-N-Methylarginine; Osmolar Concentration; Perfusion; Vasodilation | 1992 |
Endothelial dysfunction of hindquarter resistance vessels in experimental heart failure.
Topics: Acetylcholine; Animals; Arginine; Blood Vessels; Cardiac Output, Low; Chronic Disease; Dose-Response Relationship, Drug; Endothelium, Vascular; Hindlimb; Male; Myocardial Infarction; Nitroglycerin; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Vascular Resistance | 1992 |
Oxyhemoglobin stimulation of endothelin production in cultured endothelial cells.
Topics: Animals; Arginine; Blood Platelets; Cells, Cultured; Endothelins; Endothelium, Vascular; Humans; omega-N-Methylarginine; Oxyhemoglobins; Vasoconstriction | 1992 |
Nitric oxide inhibitors attenuate N-methyl-D-aspartate excitotoxicity in rat hippocampal slices.
Topics: Animals; Arginine; Calcium; Hemoglobins; Hippocampus; In Vitro Techniques; N-Methylaspartate; Nerve Degeneration; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Rats; Synapses | 1992 |
Bovine polymorphonuclear leukocytes increase sensitivity to noradrenaline in isolated mesenteric arteries.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arginine; Cattle; Free Radical Scavengers; In Vitro Techniques; Luminescent Measurements; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Neutrophils; Norepinephrine; omega-N-Methylarginine; Radioimmunoassay; Thromboxane B2 | 1992 |
The role of nitric oxide in the regional vasodilator effects of endothelin-1 in the rat.
Topics: Animals; Arginine; Endothelins; Hemodynamics; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Phenylephrine; Rats; Rats, Inbred SHR; Tachyphylaxis; Vasodilation | 1992 |
Negative inotropic effects of cytokines on the heart mediated by nitric oxide.
Topics: Animals; Arginine; Cells, Cultured; Cricetinae; Cytokines; Dose-Response Relationship, Drug; Drug Interactions; Endocardium; Epithelium; Interleukin-2; Interleukin-6; Microscopy, Electron; Myocardial Contraction; Nitric Oxide; omega-N-Methylarginine; Tumor Necrosis Factor-alpha | 1992 |
Effect of 3-morpholinosydnonimine (SIN-1), NG-nitro-L-arginine (NNA) and NG-monomethyl-L-arginine (NMMA) on isolated anaphylactic guinea-pig hearts.
Topics: Anaphylaxis; Animals; Arginine; Coronary Circulation; Eicosanoids; Guinea Pigs; Heart; Heart Rate; In Vitro Techniques; Male; Molsidomine; Myocardium; Nitroarginine; omega-N-Methylarginine; Ovalbumin | 1992 |
Nitric oxide from endothelium and smooth muscle modulates responses to sympathetic nerve stimulation: implications for endotoxin shock.
Topics: Acetylcholine; Animals; Arginine; Cycloheximide; Dexamethasone; Dinoprost; Endothelium, Vascular; Endotoxins; Iliac Artery; In Vitro Techniques; Interferon-gamma; Isometric Contraction; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Phentolamine; Prazosin; Rats; Rats, Inbred Strains; Shock, Septic | 1992 |
Effects of acute normovolemic anemia on gastric mucosal blood flow in rats: role of nitric oxide.
Topics: Acute Disease; Anemia; Animals; Arginine; Gastric Mucosa; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Regional Blood Flow; Spectrophotometry | 1992 |
Modulation of NO and endothelin by chronic increases in blood flow in canine femoral arteries.
Topics: Animals; Arginine; Dogs; Endothelins; Endothelium, Vascular; Femoral Artery; Male; Nitric Oxide; omega-N-Methylarginine; Pertussis Toxin; Regional Blood Flow; Stimulation, Chemical; Time Factors; Vasoconstriction; Vasodilation; Virulence Factors, Bordetella | 1992 |
Regulation of spontaneous EDRF release in diabetic rat aorta by oxygen free radicals.
Topics: Animals; Aorta; Arginine; Biological Assay; Diabetes Mellitus, Experimental; Free Radicals; Male; Nitric Oxide; omega-N-Methylarginine; Oxygen; Rats; Rats, Inbred Strains; Superoxide Dismutase; Vasoconstriction | 1992 |
Role of endothelium-derived nitric oxide in myocardial reactive hyperemia.
Topics: Adenosine; Animals; Arginine; Cardiomyopathies; Coronary Circulation; Dogs; Drug Combinations; Endothelium, Vascular; Hyperemia; Nitric Oxide; omega-N-Methylarginine; Pharmaceutical Vehicles; Theophylline | 1992 |
Endothelium-derived relaxing factor in pulmonary and renal circulations during hypoxia.
Topics: Animals; Arginine; Dogs; Hemodynamics; Hypoxia; Nitric Oxide; omega-N-Methylarginine; Pulmonary Circulation; Renal Circulation; Vascular Resistance | 1992 |
Characteristics of CGRP-induced relaxation in rabbit ophthalmic artery.
Topics: Animals; Arginine; Calcitonin Gene-Related Peptide; Endothelium, Vascular; In Vitro Techniques; Muscle, Smooth, Vascular; Norepinephrine; omega-N-Methylarginine; Ophthalmic Artery; Rabbits; Vasoconstriction; Vasodilation | 1992 |
Nitrite and nitrosamine synthesis by hepatocytes isolated from normal woodchucks (Marmota monax) and woodchucks chronically infected with woodchuck hepatitis virus.
Topics: Animals; Arginine; Carcinogens; Cells, Cultured; Female; Hepadnaviridae; Hepatitis, Viral, Animal; Indomethacin; Kinetics; Lipopolysaccharides; Liver; Male; Marmota; Nitrites; Nitrosamines; omega-N-Methylarginine; Rats | 1992 |
Importance of nitric oxide in canine femoral circulation: comparison of two NO inhibitors.
Topics: Acetylcholine; Animals; Arginine; Dogs; Female; Femoral Artery; Male; Nitric Oxide; Nitroarginine; Nitroglycerin; omega-N-Methylarginine; Regional Blood Flow; Vasodilation | 1992 |
Nitric oxide mediates intestinal pathology in graft-vs.-host disease.
Topics: Animals; Arginine; Cell Division; Female; Graft vs Host Disease; Intestines; Killer Cells, Natural; Macrophages; Mice; Mice, Inbred BALB C; Mice, Inbred CBA; Nitric Oxide; omega-N-Methylarginine; Tumor Necrosis Factor-alpha | 1992 |
Effect of substituted arginine compounds on superoxide production in the rabbit aorta.
Topics: Alloxan; Animals; Aorta; Arginine; In Vitro Techniques; Male; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Rabbits; Superoxides | 1991 |
Comparison of the inhibitory potencies of N(G)-methyl-, N(G)-nitro- and N(G)-amino-L-arginine on EDRF function in the rat: evidence for continuous basal EDRF release.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Blood Pressure; Hydralazine; In Vitro Techniques; Male; Nitrates; Nitric Acid; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Penicillamine; Phenylephrine; Rats; Rats, Inbred Strains; S-Nitroso-N-Acetylpenicillamine; Sympathetic Nervous System; Vasodilation; Vasopressins | 1991 |
A nitric oxide-like factor mediates nonadrenergic-noncholinergic neurogenic relaxation of penile corpus cavernosum smooth muscle.
Topics: Acetylcholine; Animals; Arginine; Humans; In Vitro Techniques; Male; Muscle Relaxation; Nitric Oxide; omega-N-Methylarginine; Oxyhemoglobins; Penis; Rabbits; Synaptic Transmission | 1991 |
NMDA receptor activation in rat hippocampus induces cyclic GMP formation through the L-arginine-nitric oxide pathway.
Topics: Animals; Arginine; Cyclic GMP; Hippocampus; In Vitro Techniques; Kinetics; N-Methylaspartate; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Rats; Receptors, N-Methyl-D-Aspartate | 1991 |
Tissue injury caused by deposition of immune complexes is L-arginine dependent.
Topics: Animals; Antigen-Antibody Complex; Arginine; Free Radicals; Inflammation; Lung; Male; Neutrophils; Nitric Oxide; omega-N-Methylarginine; Peroxidase; Rats; Skin; Superoxides | 1991 |
Role of endothelium on alpha-adrenoceptor responsiveness and prostacyclin release from the mesenteric arterial bed of the rat.
Topics: Animals; Arginine; Dose-Response Relationship, Drug; Endothelium, Vascular; Epoprostenol; In Vitro Techniques; Male; Mesenteric Arteries; Norepinephrine; omega-N-Methylarginine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1991 |
A simple and sensitive bioassay method for detection of EDRF with RFL-6 rat lung fibroblasts.
Topics: Animals; Arginine; Biological Assay; Bradykinin; Cell Line; Cyclic GMP; Fibroblasts; Lung; Nitric Oxide; omega-N-Methylarginine; Rats; Sensitivity and Specificity; Time Factors | 1991 |
Modulation of neuroeffector transmission in the guinea pig pulmonary artery by endogenous nitric oxide.
Topics: Animals; Arginine; Electric Stimulation; Female; Guinea Pigs; Male; Neuroeffector Junction; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Pulmonary Artery; Synaptic Transmission; Vasoconstriction | 1991 |
Two mechanisms mediate relaxation by bradykinin of pig coronary artery: NO-dependent and -independent responses.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arginine; Bradykinin; Coronary Vessels; Cyclic GMP; Dose-Response Relationship, Drug; In Vitro Techniques; Methylene Blue; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Potassium; Prostaglandin Endoperoxides, Synthetic; Swine; Vasodilation | 1991 |
The calcium channel antagonist S 11568 causes endothelium-dependent relaxation in canine arteries.
Topics: Animals; Arginine; Calcium Channel Blockers; Cyclic GMP; Dihydropyridines; Dogs; Endothelium, Vascular; Female; Hemoglobins; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine | 1991 |
Interleukin-1 beta-induced formation of EPR-detectable iron-nitrosyl complexes in islets of Langerhans. Role of nitric oxide in interleukin-1 beta-induced inhibition of insulin secretion.
Topics: Animals; Arginine; Cells, Cultured; Electron Spin Resonance Spectroscopy; Interleukin-1; Iron-Sulfur Proteins; Islets of Langerhans; Kinetics; Male; Nitric Oxide; Nitrites; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Recombinant Proteins | 1991 |
L-arginine abrogates salt-sensitive hypertension in Dahl/Rapp rats.
Topics: Animals; Arginine; Blood Pressure; Citrulline; Cyclic GMP; Glomerular Filtration Rate; Hypertension; Nitric Oxide; omega-N-Methylarginine; Rats; Sodium Chloride | 1991 |
Nitric oxide derived from L-arginine impairs cytoplasmic pH regulation by vacuolar-type H+ ATPases in peritoneal macrophages.
Topics: Acid-Base Equilibrium; Animals; Arginine; Bicarbonates; Cyclic AMP; Cyclic GMP; Cytoplasm; Female; Hydrogen-Ion Concentration; In Vitro Techniques; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; omega-N-Methylarginine; Peritoneal Cavity; Proton-Translocating ATPases; Sodium; Vacuoles | 1991 |
Role of superoxide radicals in anoxia reoxygenation-mediated vascular contraction.
Topics: Animals; Aorta, Thoracic; Arginine; Endothelins; Endothelium, Vascular; Hypoxia; Indomethacin; omega-N-Methylarginine; Oxygen; Oxyhemoglobins; Rats; Rats, Inbred Strains; Superoxide Dismutase; Superoxides; Vasoconstriction | 1991 |
L-Arginine, a precursor of EDRF in vitro, produces pulmonary vasodilation in lambs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Arginine; Blood Pressure; Cardiac Output; Heart Rate; Hypertension, Pulmonary; Isomerism; Methylene Blue; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Prostaglandin Endoperoxides, Synthetic; Pulmonary Artery; Purinones; Sheep; Vasodilation | 1991 |
Elevated guanosine 3':5'-cyclic monophosphate mediates the depression of nitrovasodilator reactivity in endothelium-intact blood vessels.
Topics: Animals; Aorta, Thoracic; Arginine; Cricetinae; Cyclic GMP; Endothelium, Vascular; Male; Mesocricetus; Nitric Oxide; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Sodium Nitrite; Vasodilator Agents | 1991 |
Endothelium-independent contractions to NG-monomethyl-L-arginine in canine basilar artery.
Topics: Animals; Arginine; Basilar Artery; Cyclic GMP; Dogs; Dose-Response Relationship, Drug; Endothelium, Vascular; omega-N-Methylarginine; Osmolar Concentration; Vasoconstriction | 1991 |
Cerebral vascular responses to anesthetics.
Topics: Anesthetics; Animals; Arginine; Calcium Channels; Cerebral Arteries; Cerebrovascular Circulation; Dogs; Female; Halothane; In Vitro Techniques; Isoflurane; Isometric Contraction; Male; Muscle Contraction; Muscle, Smooth, Vascular; omega-N-Methylarginine; Serotonin | 1991 |
Effects of L-arginine on systemic and renal haemodynamics in conscious dogs.
Topics: Animals; Arginine; Atropine; Blood Pressure; Cardiac Output; Dogs; Dose-Response Relationship, Drug; Heart Rate; Hemodynamics; Indomethacin; Kidney; Male; omega-N-Methylarginine; Regional Blood Flow | 1991 |
The role of nitric oxide in serotonin-induced relaxations in the canine terminal ileum and ileocolonic junction.
Topics: Acetylcholine; Animals; Arginine; Culture Techniques; Dogs; Female; Ileum; Male; Muscle Relaxation; Muscle, Smooth; Nitrates; Nitric Acid; Nitric Oxide; omega-N-Methylarginine; Serotonin | 1991 |
Endothelin-1-induced renal vasoconstriction is blunted by enalaprilat and enhanced by EDRF antagonist in awake normotensive rats.
Topics: Animals; Arginine; Blood Pressure; Enalaprilat; Endothelins; Kidney; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Renal Circulation; Vasoconstriction | 1991 |
Endothelium-dependent and independent relaxation of the rat aorta by cyclic nucleotide phosphodiesterase inhibitors.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; Aorta, Thoracic; Arginine; Endothelium, Vascular; Female; In Vitro Techniques; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Vasodilator Agents | 1991 |
Inhibition of lymphoproliferative responses by SK&F 105685, a novel anti-arthritic agent.
Topics: Animals; Arginine; Arthritis; Concanavalin A; Cyclosporine; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Indomethacin; Interleukin-2; Lymphocyte Activation; Male; omega-N-Methylarginine; Polyenes; Rats; Rats, Inbred Lew; Sirolimus; Spiro Compounds; Spleen; Time Factors; Tumor Cells, Cultured | 1991 |
Interleukin 1 induces prolonged L-arginine-dependent cyclic guanosine monophosphate and nitrite production in rat vascular smooth muscle cells.
Topics: Aminoquinolines; Animals; Arginine; Cells, Cultured; Cyclic GMP; Enzyme Activation; Guanylate Cyclase; Hemoglobins; Interleukin-1; Methylene Blue; Muscle, Smooth, Vascular; Nitrites; omega-N-Methylarginine; Protein Synthesis Inhibitors; Rats | 1991 |
Release of nitric oxide upon stimulation of nonadrenergic noncholinergic nerves in the rat gastric fundus.
Topics: Adenosine Triphosphate; Animals; Arginine; Atropine; Electric Stimulation; Female; Gastric Fundus; In Vitro Techniques; Male; Muscle Contraction; Neurotransmitter Agents; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Rats; Vasoactive Intestinal Peptide | 1991 |
A new relaxing factor in supernatant of incubated rat peritoneal neutrophils.
Topics: Animals; Aorta; Arginine; Drug Stability; Guanylate Cyclase; Neutrophils; Nitric Oxide; Nitrites; omega-N-Methylarginine; Peritoneal Cavity; Rats; Vasoconstriction; Vasodilation | 1991 |
Evidence for nitric oxide as mediator of non-adrenergic non-cholinergic relaxations induced by ATP and GABA in the canine gut.
Topics: Adenosine Triphosphate; Animals; Arginine; Colon; Dogs; Female; gamma-Aminobutyric Acid; Ileum; In Vitro Techniques; Male; Muscle Relaxation; Neurotransmitter Agents; Nitric Oxide; omega-N-Methylarginine; Tetrodotoxin | 1991 |
Involvement of nitric oxide in the reflex relaxation of the stomach to accommodate food or fluid.
Topics: Animals; Arginine; Food; Guanylate Cyclase; Guinea Pigs; Male; Methylene Blue; Muscle Relaxation; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Pressure; Reflex; Stomach | 1991 |
Nitric oxide: an endogenous modulator of leukocyte adhesion.
Topics: Animals; Antigens, CD; Arginine; Cats; CD11 Antigens; CD18 Antigens; Cell Adhesion; Endothelium, Vascular; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Splanchnic Circulation; Tetradecanoylphorbol Acetate; Venules | 1991 |
Molecular base of acetylcholine and morphine analgesia.
Topics: Acetylcholine; Analgesics; Animals; Arginine; Enzyme Activation; Guanylate Cyclase; Male; Morphine; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Pain Measurement; Phosphodiesterase Inhibitors; Phthalazines; Rats; Rats, Inbred Strains; Reaction Time | 1991 |
Selective production of endothelium-derived nitric oxide in canine femoral veins.
Topics: Acetylcholine; Adenosine Diphosphate; Adrenergic beta-Antagonists; Animals; Arginine; Azepines; Calcimycin; Dogs; Endothelium, Vascular; Female; Femoral Artery; Femoral Vein; In Vitro Techniques; Indomethacin; Isomerism; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Thrombin | 1991 |
Nitroxergic nerves mediate vagally induced relaxation in the isolated stomach of the guinea pig.
Topics: Animals; Arginine; Atropine; Guanethidine; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Male; Methylene Blue; Models, Biological; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitroglycerin; omega-N-Methylarginine; Reflex; Stomach; Vagus Nerve | 1991 |
Endogenous nitric oxide modulates adrenergic neural vasoconstriction in guinea-pig pulmonary artery.
Topics: Adrenergic alpha-Agonists; Animals; Arginine; Brimonidine Tartrate; Electric Stimulation; Epoprostenol; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Pulmonary Artery; Quinoxalines; Receptors, Adrenergic; Sympathetic Nervous System; Vasoconstriction | 1991 |
Activation of cyclic GMP formation in mouse neuroblastoma cells by a labile nitroxyl radical. An electron paramagnetic resonance/spin trapping study.
Topics: Animals; Arginine; Benzenesulfonates; Cyclic AMP; Electron Spin Resonance Spectroscopy; Enzyme Activation; Ferricyanides; Free Radicals; Guanylate Cyclase; Methylene Blue; Mice; NADP; Neuroblastoma; Nitrogen Oxides; Nitroso Compounds; omega-N-Methylarginine; Receptors, Muscarinic; Tumor Cells, Cultured | 1991 |
NG-monomethyl-L-arginine and NG-nitro-L-arginine inhibit endothelium-dependent relaxations in human isolated omental arteries.
Topics: Acetylcholine; Adult; Aged; Arginine; Arteries; Endothelium, Vascular; Female; Humans; In Vitro Techniques; Male; Middle Aged; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Omentum; Regional Blood Flow | 1991 |
NG-nitro-L-arginine methyl ester attenuates vasodilator responses to acetylcholine but enhances those to sodium nitroprusside.
Topics: Acetylcholine; Animals; Arginine; Drug Interactions; Hepatic Artery; In Vitro Techniques; Liver; Male; NG-Nitroarginine Methyl Ester; Nitroprusside; omega-N-Methylarginine; Rabbits; Rats; Rats, Inbred Strains; Splanchnic Circulation; Vasodilation | 1991 |
Effect of nitric oxide on circular muscle of the canine small intestine.
Topics: Animals; Arginine; Dogs; Female; Hemoglobins; In Vitro Techniques; Jejunum; Male; Membrane Potentials; Muscle, Smooth; Neural Inhibition; Neurotransmitter Agents; Nitric Oxide; omega-N-Methylarginine | 1991 |
The effects of pyrogallol and hydroquinone on the response to NANC nerve stimulation in the rat anococcygeus and the bovine retractor penis muscles.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Autonomic Nervous System; Cattle; Electric Stimulation; Hydroquinones; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; omega-N-Methylarginine; Penis; Pyrogallol; Rats; Superoxides | 1990 |
Release of endothelium-derived relaxing factor from pig cultured aortic endothelial cells, as assessed by changes in endothelial cell cyclic GMP content, is inhibited by a phorbol ester.
Topics: Adenosine Triphosphate; Animals; Aorta, Thoracic; Arginine; Calcimycin; Catalase; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Hemoglobins; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Phorbol 12,13-Dibutyrate; Substance P; Superoxide Dismutase; Swine | 1990 |
Inhibition of nitric oxide synthase blocks N-methyl-D-aspartate-, quisqualate-, kainate-, harmaline-, and pentylenetetrazole-dependent increases in cerebellar cyclic GMP in vivo.
Topics: Alkaloids; Amino Acid Oxidoreductases; Amino Acids; Animals; Arginine; Cerebellum; Cyclic GMP; Dose-Response Relationship, Drug; Harmaline; Male; Mice; Mice, Inbred Strains; Nitric Oxide Synthase; omega-N-Methylarginine; Pentylenetetrazole; Receptors, Amino Acid; Receptors, Cell Surface | 1990 |
Kinetic characteristics of nitric oxide synthase from rat brain.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Binding, Competitive; Brain; Diencephalon; Guanylate Cyclase; Kinetics; Male; NADP; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Ornithine; Rats; Synaptosomes; Telencephalon; Tissue Distribution | 1990 |
Low basal and stimulated release of nitric oxide in atherosclerotic epicardial coronary arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adolescent; Adult; Arginine; Arteriosclerosis; Bradykinin; Child; Child, Preschool; Coronary Vessels; Dose-Response Relationship, Drug; Drug Synergism; Endothelium, Vascular; Humans; Middle Aged; Nitric Oxide; omega-N-Methylarginine; Prostaglandin Endoperoxides, Synthetic; Substance P; Vasoconstriction; Vasodilation | 1990 |
Mechanism underlying the response to vasodilator nerve stimulation in isolated dog and monkey cerebral arteries.
Topics: Animals; Arginine; Cerebral Arteries; Dogs; Electric Stimulation; Female; In Vitro Techniques; Macaca; Male; Nervous System Physiological Phenomena; Nicotine; Nitric Oxide; Nitroglycerin; omega-N-Methylarginine; Substance P; Vasodilation | 1990 |
Role of reactive nitrogen intermediate production in alveolar macrophage-mediated cytostatic activity induced by bleomycin lung damage in rats.
Topics: Aconitate Hydratase; Animals; Arginine; Bleomycin; Cytotoxicity, Immunologic; DNA Replication; Kinetics; Leukemia L1210; Lung; Macrophage Activation; Macrophages; Male; Mice; Nitriles; Nitrites; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Reference Values | 1990 |
Modulation of autonomic neuroeffector transmission by nitric oxide in guinea pig ileum.
Topics: Acetylcholine; Animals; Arginine; Choline; Electric Stimulation; Female; Guinea Pigs; Ileum; In Vitro Techniques; Isomerism; Kinetics; Male; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Nitric Oxide; omega-N-Methylarginine; Substance P; Synaptic Transmission | 1990 |
Characterization of the L-arginine:nitric oxide pathway in human platelets.
Topics: Adenosine Diphosphate; Amino Acid Oxidoreductases; Arachidonic Acid; Arachidonic Acids; Arginine; Blood Platelets; Calcimycin; Humans; In Vitro Techniques; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Ornithine; Platelet Aggregation; Platelet Aggregation Inhibitors; Stereoisomerism; Thrombin | 1990 |
Endogenous nitric oxide release required for long-term synaptic depression in the cerebellum.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acid Oxidoreductases; Animals; Arginine; Cerebellum; Cyclic GMP; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamic Acid; Hemoglobins; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Potassium; Purkinje Cells; Pyridines; Quinoxalines; Rats; Rats, Inbred Strains; Synapses | 1991 |
Acetylcholine-induced vasodilatation in rabbit hindlimb in vivo is not inhibited by analogues of L-arginine.
Topics: Acetylcholine; Animals; Arginine; Endothelium, Vascular; Female; Femoral Artery; Hindlimb; Male; Microspheres; Nitric Oxide; Nitroarginine; Nitroglycerin; omega-N-Methylarginine; Rabbits; Regional Blood Flow; Substance P; Vascular Resistance; Vasodilation | 1991 |
The role of nitric oxide in mediating endothelium dependent relaxations in the human epicardial coronary artery.
Topics: Adolescent; Adult; Arginine; Child; Child, Preschool; Coronary Vessels; Endothelium, Vascular; Humans; In Vitro Techniques; Indomethacin; Infant; Middle Aged; Nitric Oxide; omega-N-Methylarginine; Substance P | 1990 |
Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo.
Topics: Amino Acid Oxidoreductases; Animals; Aorta, Thoracic; Arginine; Blood Pressure; Endothelium, Vascular; Heart Rate; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Ornithine; Rats; Rats, Inbred Strains; Swine; Vasoconstriction | 1990 |
Evidence that endogenous nitric oxide modulates oedema formation induced by substance P.
Topics: Animals; Arginine; Edema; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Regional Blood Flow; Skin; Stereoisomerism; Substance P | 1990 |
Molecular basis of "suppressor" macrophages. Arginine metabolism via the nitric oxide synthetase pathway.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Division; Cells, Cultured; Concanavalin A; Drug Synergism; In Vitro Techniques; Lipopolysaccharides; Lymphocyte Activation; Macrophages; Mice; Nitric Oxide Synthase; omega-N-Methylarginine; Phytohemagglutinins; Rats; Rats, Inbred F344; Staphylococcal Protein A | 1991 |
The nitric oxide synthase II inhibitor NG-nitro-L-arginine stimulates pancreatic islet insulin release in vitro, but not in the perfused pancreas.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Glucose; In Vitro Techniques; Insulin; Islets of Langerhans; Male; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Oxidation-Reduction; Perfusion; Rats; Rats, Inbred Strains | 1991 |
Identification of N-iminoethyl-L-ornithine as an irreversible inhibitor of nitric oxide synthase in phagocytic cells.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Line; Cytosol; Humans; In Vitro Techniques; Interferon-gamma; Lipopolysaccharides; Male; Neutrophils; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Ornithine; Phagocytes; Platelet Aggregation; Rats; Rats, Inbred Strains | 1991 |
Impairment of the L-arginine-nitric oxide pathway in mast cells from spontaneously hypertensive rats.
Topics: Animals; Arginine; Blood Platelets; Calcimycin; Cyclic AMP; Cyclic GMP; Histamine Release; Humans; In Vitro Techniques; Kinetics; Mast Cells; Nitric Oxide; omega-N-Methylarginine; p-Methoxy-N-methylphenethylamine; Platelet Aggregation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reference Values; Thrombin | 1991 |
The effect of nitric oxide generators on ischemia reperfusion injury and histamine release in isolated perfused guinea-pig heart.
Topics: Animals; Arginine; Calcium; Coronary Vessels; Cytoplasmic Granules; Guinea Pigs; Histamine Release; Male; Mast Cells; Molsidomine; Myocardial Reperfusion Injury; Nitric Oxide; Nitroprusside; omega-N-Methylarginine | 1991 |
Rat mast cells synthesize a nitric oxide like-factor which modulates the release of histamine.
Topics: Animals; Arginine; Blood Platelets; Cyclic GMP; Guanylate Cyclase; Histamine Release; Humans; Indomethacin; Male; Mast Cells; Nitric Oxide; omega-N-Methylarginine; Oxyhemoglobins; Platelet Aggregation; Rats; Rats, Inbred Strains; Superoxide Dismutase; Thrombin | 1991 |
Endothelial function of human gastroepiploic artery. Implications for its use as a bypass graft.
Topics: Arginine; Coronary Artery Bypass; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; In Vitro Techniques; Indomethacin; Nitroglycerin; omega-N-Methylarginine; Stomach; Substance P; Vascular Patency; Vasodilation | 1991 |
Contribution of nitric oxide synthase to luminol-dependent chemiluminescence generated by phorbol-ester-activated Kupffer cells.
Topics: Acridines; Amino Acid Oxidoreductases; Animals; Arginine; Catalase; Cell-Free System; In Vitro Techniques; Kupffer Cells; Luminescent Measurements; Luminol; Male; NADH, NADPH Oxidoreductases; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Xanthine; Xanthine Oxidase; Xanthines | 1991 |
Glucocorticoids inhibit the induction of nitric oxide synthase and the related cell damage in adenocarcinoma cells.
Topics: Amino Acid Oxidoreductases; Arginine; Cell Survival; Cortodoxone; Dexamethasone; Enzyme Induction; Humans; Hydrocortisone; Kinetics; Lipopolysaccharides; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Progesterone; Tumor Cells, Cultured | 1991 |
Human colorectal adenocarcinoma cells: differential nitric oxide synthesis determines their ability to aggregate platelets.
Topics: Adenocarcinoma; Amino Acid Oxidoreductases; Arginine; Colorectal Neoplasms; Epoprostenol; Humans; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Aggregation; Purinones; Tumor Cells, Cultured; Vasodilator Agents | 1991 |
Effect of nitric oxide generators on ischemia-reperfusion injury and histamine release in isolated perfused guinea pig heart.
Topics: Animals; Arginine; Guinea Pigs; Histamine Release; In Vitro Techniques; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; omega-N-Methylarginine; Perfusion | 1991 |
Effects of guanidino compounds on the endothelium-derived relaxing factor inhibitor NG-monomethyl L-arginine.
Topics: Animals; Aorta, Thoracic; Arginine; Cyclic GMP; Endothelium, Vascular; Guanidines; Homoarginine; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains | 1991 |
On-line measurement of nitric oxide release from organic nitrates in the intact coronary circulation.
Topics: Animals; Arginine; Bradykinin; Coronary Vessels; In Vitro Techniques; Molsidomine; Nitric Oxide; Nitroglycerin; omega-N-Methylarginine; Oxyhemoglobins; Rabbits; Substance P; Trypsin; Vasodilation | 1991 |
Relationship between sensory neuropeptides and other local vasoactive mediators in modulating gastric mucosal integrity.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arginine; Blood Pressure; Capsaicin; Gastric Mucosa; Male; Microcirculation; Muscle, Smooth, Vascular; Neurons, Afferent; Neuropeptides; omega-N-Methylarginine; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Inbred Strains; Substance P; Vasodilation | 1991 |
Synthesis of nitric oxide in the bovine retina.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Calcium; Cattle; Cytosol; Egtazic Acid; Kinetics; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Retina; Rod Cell Outer Segment | 1991 |
Interleukin-1 beta-induced nitric oxide production in isolated rat pancreatic islets requires gene transcription and may lead to inhibition of the Krebs cycle enzyme aconitase.
Topics: Aconitate Hydratase; Amino Acid Oxidoreductases; Animals; Arginine; Dactinomycin; Glucose; Insulin; Insulin Secretion; Interleukin-1; Islets of Langerhans; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Oxidation-Reduction; Rats; Rats, Inbred Strains; Tosyllysine Chloromethyl Ketone; Transcription, Genetic | 1991 |
Absence of implication of L-arginine/nitric oxide pathway on neuronal cell injury induced by L-glutamate or hypoxia.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Brain; Cell Hypoxia; Cells, Cultured; Cyclic GMP; Dizocilpine Maleate; Fetus; Glutamates; Glutamic Acid; Kainic Acid; Kinetics; N-Methylaspartate; Neuroglia; Neurons; Nitric Oxide; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Quisqualic Acid; Rats | 1991 |
A requirement for the intercellular messenger nitric oxide in long-term potentiation.
Topics: Amino Acid Oxidoreductases; Arginine; Hippocampus; In Vitro Techniques; Neuronal Plasticity; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Synaptic Membranes; Synaptic Transmission | 1991 |
Endogenous nitric oxide is present in the exhaled air of rabbits, guinea pigs and humans.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Breath Tests; Female; Guinea Pigs; Humans; Luminescent Measurements; Lung; Male; Mass Spectrometry; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rabbits | 1991 |
Purification and characterization of a human NO synthase.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Calmodulin; Cerebellum; Chromatography, Affinity; Chromatography, Gel; Egtazic Acid; Electrophoresis, Polyacrylamide Gel; Humans; Imidazoles; Kinetics; Molecular Weight; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Temporal Lobe; Trifluoperazine | 1991 |
NG-monomethyl-L-arginine increases platelet deposition on damaged endothelium in vivo. A scanning electron microscopic study.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Endothelium, Vascular; Microscopy, Electron, Scanning; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Rabbits | 1991 |
Endothelium-derived nitric oxide as a mediator of acetylcholine-induced coronary vasodilation in dogs.
Topics: Acetylcholine; Adenosine; Animals; Arginine; Coronary Circulation; Dogs; Endothelium, Vascular; Female; Male; Muscle Tonus; Nitric Oxide; omega-N-Methylarginine; Vasodilation | 1991 |
Prevention of cyclosporine A-induced vascular toxicity by pentoxifylline.
Topics: Acetylcholine; Animals; Arginine; Colforsin; Cyclosporine; Endothelium, Vascular; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Neuromuscular Depolarizing Agents; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Pentoxifylline; Phenylephrine; Rats; Rats, Inbred Strains; Vascular Diseases | 1991 |
Nitric oxide synthase in cultured endocardial cells of the pig.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Calcium; Cells, Cultured; Cytosol; Endocardium; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Swine | 1991 |
Coronary vasodilatation induced by endotoxin in the rabbit isolated perfused heart is nitric oxide-dependent and inhibited by dexamethasone.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Coronary Vessels; Dexamethasone; Endotoxins; In Vitro Techniques; Lipopolysaccharides; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Ornithine; Prostaglandin Endoperoxides, Synthetic; Rabbits; Vasodilator Agents | 1991 |
Nitric oxide from vascular smooth muscle cells: regulation of platelet reactivity and smooth muscle cell guanylate cyclase.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Atrial Natriuretic Factor; Blood Platelets; Cattle; Cyclic GMP; Cycloheximide; Escherichia coli; Guanylate Cyclase; Humans; In Vitro Techniques; Lipopolysaccharides; Macrophages; Mice; Monocytes; Muscle, Smooth; Muscle, Smooth, Vascular; Nitric Oxide; Nitroglycerin; omega-N-Methylarginine; Superoxide Dismutase; Thrombin | 1991 |
Differential effect of cyclic GMP on the release of endothelin-1 from cultured endothelial cells and intact porcine aorta.
Topics: Animals; Aorta, Thoracic; Arginine; Cells, Cultured; Cyclic GMP; Endothelins; Endothelium, Vascular; In Vitro Techniques; Nitric Oxide; omega-N-Methylarginine; Radioimmunoassay; Swine; Thrombin | 1991 |
Differential effects of endothelin-1 and big endothelin on canine kidneys.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Aspirin; Dogs; Endothelin-1; Endothelins; Female; Infusions, Intra-Arterial; Kidney; Lysine; Male; Nitric Oxide; omega-N-Methylarginine; Prostaglandins; Protein Precursors; Renal Circulation | 1991 |
Pulmonary vascular reactivity to endothelin-1 in normal and chronically pulmonary hypertensive rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arginine; Calcimycin; Endothelins; Hemodynamics; Hypertension, Pulmonary; Hypoxia; In Vitro Techniques; Male; Muscle Tonus; Nitric Oxide; omega-N-Methylarginine; Prostaglandin Endoperoxides, Synthetic; Pulmonary Circulation; Rats; Rats, Inbred Strains; Vasodilation | 1991 |
Studies on the importance of the proposed release of nitric oxide from platelets.
Topics: Arginine; Blood Platelets; Collagen; Humans; Iloprost; Nitric Oxide; Nitroglycerin; omega-N-Methylarginine; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombin | 1991 |
Effects of L-NMMA and L-NNA on the selective ATP-induced enhancement of intratumoral blood flow.
Topics: Adenosine; Adenosine Triphosphate; Animals; Arginine; Brain Neoplasms; Glioma; Male; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Regional Blood Flow; Tumor Cells, Cultured | 1992 |
Endogenous nitric oxide as a mediator of gastric mucosal vasodilatation during acid secretion.
Topics: Animals; Arginine; Blood Pressure; Gastric Acid; Gastric Mucosa; Male; Nitric Oxide; omega-N-Methylarginine; Pentagastrin; Rats; Rats, Inbred Strains; Regional Blood Flow; Vasodilation | 1992 |
Electrically-induced, nerve-mediated relaxation of rabbit urethra involves nitric oxide.
Topics: Animals; Arginine; Arginine Vasopressin; Dose-Response Relationship, Drug; Electric Stimulation; Endothelins; Female; In Vitro Techniques; Methylene Blue; Muscle Contraction; Muscle Relaxation; Nitric Oxide; Nitroarginine; Norepinephrine; omega-N-Methylarginine; Rabbits; Urethra | 1992 |
Attenuation of the vasoconstrictor effects of thromboxane and endothelin by nitric oxide in the human fetal-placental circulation.
Topics: Acetylcholine; Arginine; Calcimycin; Endothelins; Female; Fetus; Humans; Nitric Oxide; Nitroarginine; Nitroglycerin; omega-N-Methylarginine; Placenta; Pregnancy; Prostaglandin Endoperoxides, Synthetic; Vasoconstriction | 1992 |
Inhibition of the reactive proliferation of lymphocytes by activated macrophages: the role of nitric oxide.
Topics: Arginine; Concanavalin A; Humans; Lymphocyte Activation; Macrophage Activation; Macrophages; Nitric Oxide; omega-N-Methylarginine; Thymidine | 1992 |
Interleukin-1 impairs both vascular contraction and relaxation in rabbit isolated aorta.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Dose-Response Relationship, Drug; In Vitro Techniques; Interleukin-1; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; omega-N-Methylarginine; Rabbits; Recombinant Proteins | 1992 |
Inhibition of nitric oxide, bradykinin, and prostaglandins in normal rats.
Topics: Animals; Arginine; Bradykinin; Hemodynamics; Indomethacin; Male; Nitric Oxide; omega-N-Methylarginine; Prostaglandin Antagonists; Rats; Rats, Inbred Strains; Regional Blood Flow | 1992 |
Nonprostanoid endothelium-derived factors inhibit renin release.
Topics: Animals; Arginine; Endothelins; In Vitro Techniques; Isoproterenol; Kidney Cortex; Male; Melitten; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Renin | 1992 |
Kinins, nitric oxide, and the hypotensive effect of captopril and ramiprilat in hypertension.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Arginine; Biphenyl Compounds; Blood Pressure; Captopril; Hypertension; Imidazoles; Kinins; Losartan; Male; Nitric Oxide; omega-N-Methylarginine; Pyrroles; Ramipril; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrazoles | 1992 |
Isolation and identification of methylarginines from bovine brain.
Topics: Animals; Arginine; Brain; Cattle; Chromatography, High Pressure Liquid; Electrophoresis, Paper; omega-N-Methylarginine | 1992 |
Endothelium-dependent nonadrenergic, noncholinergic neural relaxation in guinea pig pulmonary artery.
Topics: Acetamides; Adenosine Triphosphate; Animals; Arginine; Atropine; Autonomic Nervous System; Capsaicin; Chymotrypsin; Drug Interactions; Endothelium, Vascular; Guinea Pigs; In Vitro Techniques; Indomethacin; Lipoxygenase Inhibitors; Male; Muscle Contraction; Muscle, Smooth, Vascular; omega-N-Methylarginine; Phenyl Ethers; Propranolol; Prostaglandin Endoperoxides, Synthetic; Pulmonary Artery; Vasoactive Intestinal Peptide | 1992 |
Independence of the pattern of early cytokine release from autoregulation by nitric oxide.
Topics: Adenocarcinoma; Animals; Arginine; Culture Media; Cytokines; Female; Homeostasis; Interferon-gamma; L Cells; Lipopolysaccharides; Macrophage Activation; Macrophages; Male; Mammary Neoplasms, Experimental; Mice; Nitric Oxide; Nitrites; omega-N-Methylarginine; Peritoneal Cavity; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1991 |
Interaction of pressure- and flow-induced responses in porcine coronary resistance vessels.
Topics: Animals; Arginine; Arterioles; Coronary Circulation; Coronary Vessels; Endothelium, Vascular; Female; Indomethacin; Male; omega-N-Methylarginine; Pressure; Swine; Vascular Resistance; Vasodilation | 1991 |
Endothelium-dependent vasodilation of canine coronary collateral vessels.
Topics: Acetylcholine; Animals; Arginine; Bradykinin; Collateral Circulation; Coronary Vessels; Dinoprost; Dogs; Endothelium, Vascular; Female; Male; omega-N-Methylarginine; Vasodilation | 1991 |
Effect of an arginine analogue on acetylcholine-induced coronary microvascular dilatation in dogs.
Topics: Acetylcholine; Animals; Arginine; Arterioles; Coronary Vessels; Dogs; Endothelium, Vascular; Female; Male; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Vasodilation | 1991 |
Effect of bradykinin antagonists, NG-monomethyl-L-arginine and L-NG-nitro arginine on phospholipase A2 induced oedema in rat paw.
Topics: Animals; Arginine; Bradykinin; Edema; Evans Blue; Foot; Kininogens; Male; Methysergide; Nitroarginine; omega-N-Methylarginine; Phospholipases A; Phospholipases A2; Rats; Rats, Inbred Strains | 1991 |
Role of nitric oxide formation in the regulation of haemodynamics and the release of noradrenaline and adrenaline.
Topics: Animals; Arginine; Chromatography, High Pressure Liquid; Epinephrine; Female; Hemodynamics; Injections, Intravenous; Male; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Phenylephrine; Rabbits | 1991 |
Endothelium-derived relaxing factor and the vascular reply to systemic hypertension.
Topics: Acute Disease; Animals; Arginine; Chronic Disease; Desoxycorticosterone; Hypertension; Male; Muscle, Smooth, Vascular; Nephrectomy; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Renal Circulation; Sodium, Dietary; Vasomotor System | 1991 |
Effects of NG-substituted analogues of L-arginine on NANC relaxation of the rat anococcygeus and bovine retractor penis muscles and the bovine penile artery.
Topics: Animals; Arginine; Arteries; Autonomic Nervous System; Cattle; Guanethidine; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Muscle, Smooth, Vascular; Muscles; Nitroarginine; omega-N-Methylarginine; Penis; Rats; Serotonin; Stereoisomerism; Vasodilation | 1991 |
Regional coronary haemodynamic effects of two inhibitors of nitric oxide synthesis in anaesthetized, open-chest dogs.
Topics: Acetylcholine; Anesthesia; Animals; Arginine; Blood Pressure; Coronary Circulation; Dogs; Female; Heart Rate; Hemodynamics; In Vitro Techniques; Male; Microspheres; Muscle Tonus; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Vascular Resistance | 1991 |
Omega-3 polyunsaturated fatty acids augment endothelium-dependent vasorelaxation by enhanced release of EDRF and vasodilator prostaglandins.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Endothelium, Vascular; Fatty Acids, Omega-3; In Vitro Techniques; Indomethacin; Nitric Oxide; omega-N-Methylarginine; Prostaglandins; Rats; Rats, Inbred Strains; Vasodilation | 1991 |
Vasodilatation by endothelium-derived nitric oxide as a major determinant of noradrenaline release.
Topics: Animals; Arginine; Blood Pressure; Cardiac Output; Endothelium, Vascular; Female; Heart Rate; Hemodynamics; Male; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Phenylephrine; Pressoreceptors; Rabbits; Vascular Resistance; Vasodilation | 1991 |
Sponge allograft effector cells exert suppressor function via an L-arginine-dependent mechanism.
Topics: Animals; Arginine; Cells, Cultured; Cytotoxicity, Immunologic; Lymphocyte Transfusion; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred ACI; Rats, Inbred BN; Rats, Inbred Lew; Spleen; T-Lymphocytes, Regulatory; Transplantation, Homologous | 1991 |
A new role for prostaglandins in the regulation of peripheral resistance.
Topics: Acetylcholine; Animals; Arginine; Arterioles; Blood Flow Velocity; Erythrocytes; Indomethacin; Male; Muscles; omega-N-Methylarginine; Prostaglandins; Rats; Rats, Inbred Strains; Vascular Resistance; Vasodilation | 1991 |
Mechanism of impaired responses of cerebral arterioles during diabetes mellitus.
Topics: Animals; Arginine; Arterioles; Brain; Bridged Bicyclo Compounds, Heterocyclic; Diabetes Mellitus, Experimental; Fatty Acids, Unsaturated; Hydrazines; Indomethacin; Nitric Oxide; omega-N-Methylarginine; Prostaglandins H; Rats; Receptors, Prostaglandin; Receptors, Thromboxane; Receptors, Thromboxane A2, Prostaglandin H2; Thromboxanes; Vasoconstriction; Vasodilation | 1991 |
Inhibition of nitric oxide generation affects the induction of diabetes by streptozocin in mice.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Islets of Langerhans; Isomerism; Male; Mice; Mice, Inbred CBA; Necrosis; Nitric Oxide; omega-N-Methylarginine; Streptozocin | 1991 |
Nitric oxide synthesis in the CNS endothelium and macrophages differs in its sensitivity to inhibition by arginine analogues.
Topics: Animals; Arginine; Central Nervous System; Cyclic GMP; Endothelium; In Vitro Techniques; Macrophages; Mice; N-Methylaspartate; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Rats | 1991 |
Endothelium independent protective effect of NG-monomethyl-L-arginine on endotoxin-induced alterations of vascular reactivity.
Topics: Animals; Aorta, Thoracic; Arginine; Endothelium, Vascular; Endotoxins; Male; Methylene Blue; Muscle Contraction; Muscle, Smooth, Vascular; Nitrates; Nitric Acid; omega-N-Methylarginine; Rats; Rats, Inbred Strains | 1991 |
Development and mechanism of a specific supersensitivity to nitrovasodilators after inhibition of vascular nitric oxide synthesis in vivo.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Cyclic GMP; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroglycerin; Nitroprusside; omega-N-Methylarginine; Ornithine; Rats; Rats, Inbred Strains; Vasoconstriction; Vasodilation; Vasodilator Agents | 1991 |
Haemodynamic responses to NG-monomethyl-L-arginine in spontaneously hypertensive and normotensive Wistar-Kyoto rats.
Topics: Animals; Arginine; Dose-Response Relationship, Drug; Hemodynamics; Hypertension; In Vitro Techniques; Male; Muscle Tonus; Muscle, Smooth, Vascular; omega-N-Methylarginine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Stereoisomerism; Vascular Resistance | 1991 |
Characterization of the 5-HT receptor mediating endothelium-dependent relaxation in porcine vena cava.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; alpha-Methyltyrosine; Animals; Animals, Newborn; Arginine; Endothelium, Vascular; Ketanserin; Methyltyrosines; Muscle Relaxation; Muscle, Smooth, Vascular; omega-N-Methylarginine; Prostaglandin Endoperoxides, Synthetic; Receptors, Serotonin; Serotonin; Swine; Venae Cavae | 1991 |
The involvement of endothelium-derived relaxing factor in the regulation of renal cortical blood flow in the rat.
Topics: Animals; Arginine; Blood Pressure; Dopamine; Indomethacin; Kidney Cortex; Lasers; Male; Nitric Oxide; Nitroarginine; Nitrous Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Renal Circulation | 1991 |
Effects of indomethacin, endothelium-denudation, methylene blue and L-NG-monomethyl arginine on the vasoactive effects of endothelin-3.
Topics: Animals; Arginine; Cholic Acids; Endothelins; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Male; Mesenteric Arteries; Methylene Blue; Muscle Contraction; Muscle, Smooth, Vascular; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Vasoconstriction; Vasodilation | 1991 |
Endothelium-dependent contraction and relaxation of the human and canine internal mammary artery: studies on bypass graft vasospasm.
Topics: Acetylcholine; Animals; Arginine; Dogs; Endothelins; Female; Humans; Hypoxia; In Vitro Techniques; Male; Mammary Arteries; Methacholine Chloride; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroprusside; Norepinephrine; omega-N-Methylarginine | 1991 |
Nitric oxide synthesis in the in vivo allograft response: a possible regulatory mechanism.
Topics: Animals; Arginine; Cell Movement; Cytotoxicity, Immunologic; Male; Nitric Oxide; Nitrous Oxide; omega-N-Methylarginine; Prostheses and Implants; Rats; Rats, Inbred ACI; Rats, Inbred Lew; Spleen; Transplantation, Homologous | 1991 |
Agents that modify EDRF formation alter antiplatelet properties of brain arteriolar endothelium in vivo.
Topics: Acetylcholine; Administration, Topical; Animals; Arginase; Arginine; Arterioles; Blood Platelets; Cerebrovascular Circulation; Endothelium, Vascular; Injections, Intravenous; Male; Mice; Mice, Inbred ICR; Nitric Oxide; omega-N-Methylarginine; Platelet Aggregation; Platelet Aggregation Inhibitors | 1991 |
Contraction and relaxation of rat aorta in response to ATP.
Topics: Adenosine Triphosphate; Animals; Aorta; Arginine; Endothelins; In Vitro Techniques; Norepinephrine; omega-N-Methylarginine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Serotonin; Vasoconstriction; Vasodilation | 1991 |
Effect of NG-monomethyl-L-arginine on arcade arterioles of rat spinotrapezius muscles.
Topics: Animals; Arginine; Arterioles; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Muscles; omega-N-Methylarginine; Osmolar Concentration; Rats; Rats, Inbred Strains; Rest; Vasoconstrictor Agents; Vasodilator Agents | 1991 |
Role of nitric oxide in renal medullary oxygenation. Studies in isolated and intact rat kidneys.
Topics: Acute Kidney Injury; Animals; Arginine; Disease Models, Animal; Hypoxia; In Vitro Techniques; Kidney Medulla; Nitric Oxide; omega-N-Methylarginine; Oxygen; Perfusion; Rats; Rats, Inbred Strains; Vasodilation | 1991 |
Endothelium-derived relaxing factor: evidence that it regulates pulmonary vascular resistance in the isolated neonatal guinea pig lung.
Topics: Angiotensin II; Animals; Animals, Newborn; Arginine; Blood Pressure; Bradykinin; Guinea Pigs; In Vitro Techniques; Nitric Oxide; omega-N-Methylarginine; Pulmonary Circulation; Vascular Resistance | 1991 |
Inhibition of human platelet reactivity by endothelium-derived relaxing factor from human umbilical vein endothelial cells in suspension: blockade of aggregation and secretion by an aspirin-insensitive mechanism.
Topics: Arginine; Aspirin; Blood Platelets; Endothelium, Vascular; Humans; Nitric Oxide; omega-N-Methylarginine; Platelet Aggregation; Serotonin; Superoxide Dismutase; Thrombin; Umbilical Veins | 1991 |
NG-monomethyl-l-arginine (NMA) restores arterial blood pressure but reduces cardiac output in a canine model of endotoxic shock.
Topics: Animals; Arginine; Blood Pressure; Cardiac Output; Dogs; Endotoxins; Femoral Artery; Hemodynamics; Male; omega-N-Methylarginine; Regional Blood Flow; Shock, Septic; Vascular Resistance | 1991 |
Inhibition by L-arginine of the endothelin-mediated increase in cytosolic calcium in human neutrophils.
Topics: Arginine; Calcium; Cytosol; Dose-Response Relationship, Drug; Endothelins; Fluorescent Dyes; Fura-2; Humans; In Vitro Techniques; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; omega-N-Methylarginine | 1991 |
Acetylcholine vasodilation of resistance vessels in vivo may not entirely depend on newly synthesized nitric oxide.
Topics: Acetylcholine; Animals; Arginine; Blood Pressure; Cats; Denervation; Endothelium, Vascular; Female; Heart Rate; Hindlimb; Male; Nitric Oxide; omega-N-Methylarginine; Regional Blood Flow; Vascular Resistance; Vasodilation | 1991 |
Effects of acute nitric oxide inhibition on rat glomerular microcirculation.
Topics: Animals; Arginine; Hemodynamics; Kidney Glomerulus; Male; Microcirculation; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Time Factors; Vascular Resistance | 1991 |
Evidence of a role for compounds derived from arginine in coronary response to serotonin in vivo.
Topics: Animals; Arginine; Coronary Vessels; Dinoprost; Dogs; Drug Combinations; Female; Male; Nitroarginine; omega-N-Methylarginine; Serotonin; Vasoconstriction | 1991 |
Endothelium-derived relaxing factor in regulation of basal cardiopulmonary and renal function.
Topics: Animals; Arginine; Diuresis; Dogs; Heart; Hemodynamics; Homeostasis; Hormones; Kidney; Lung; Nitric Oxide; omega-N-Methylarginine; Renal Circulation | 1991 |
L-arginine-dependent macrophage effector functions inhibit metabolic activity of Mycobacterium leprae.
Topics: Animals; Arginase; Arginine; Cells, Cultured; Macrophage Activation; Macrophages; Mice; Mice, Inbred BALB C; Mycobacterium leprae; Nitric Oxide; omega-N-Methylarginine; Oxygen | 1991 |
Difference in pressor responses to NG-monomethyl-L-arginine between conscious and anesthetized rats.
Topics: Anesthetics; Animals; Arginine; Blood Pressure; Chloralose; Consciousness; Dose-Response Relationship, Drug; Male; Nitric Oxide; omega-N-Methylarginine; Pentobarbital; Phenylephrine; Rats; Rats, Inbred Strains; Urethane | 1991 |
Inhibition of nitric oxide synthesis induces a significant reduction in local cerebral blood flow in the rat.
Topics: Animals; Arginine; Autoradiography; Blood Pressure; Cerebrovascular Circulation; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains | 1991 |
Alkaline buffers release EDRF from bovine cultured aortic endothelial cells.
Topics: Animals; Arginine; Buffers; Cattle; Cells, Cultured; Cyclohexanones; Endothelium, Vascular; Epoprostenol; Hydrogen-Ion Concentration; Lipoprotein Lipase; Nitric Oxide; omega-N-Methylarginine; Platelet Activating Factor; Pyrimidinones; Thiazoles | 1991 |
Cardiovascular actions of inhibitors of endothelium-derived relaxing factor (nitric oxide) formation/release in anesthetized dogs.
Topics: Anesthesia; Animals; Arginine; Blood Pressure; Cardiac Output; Coronary Circulation; Dogs; Dose-Response Relationship, Drug; Heart; Hemodynamics; Indomethacin; Myocardium; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Vasoconstriction | 1991 |
Effect of endogenous nitric oxide on mitochondrial respiration of rat hepatocytes in vitro and in vivo.
Topics: Aconitate Hydratase; Animals; Arginine; Aspartate Aminotransferases; Cells, Cultured; Electron Transport; In Vitro Techniques; Kupffer Cells; Lipopolysaccharides; Liver; Male; Mitochondria, Liver; NAD(P)H Dehydrogenase (Quinone); Nitric Oxide; Nitrogen Oxides; omega-N-Methylarginine; Propionibacterium acnes; Proteins; Quinone Reductases; Rats; Rats, Inbred Strains | 1991 |
Interactions between nitroglycerin and endothelium in vascular smooth muscle relaxation.
Topics: Animals; Arginine; Endothelium, Vascular; Epinephrine; Indomethacin; Male; Muscle, Smooth, Vascular; Nitroglycerin; omega-N-Methylarginine; Oxyhemoglobins; Papaverine; Rats; Rats, Inbred Strains; Superoxide Dismutase; Vasoconstriction; Vasodilation | 1991 |
Generation of nitric oxide from organic nitrovasodilators during passage through the coronary vascular bed and its role in coronary vasodilation and nitrate tolerance.
Topics: Animals; Arginine; Coronary Vessels; Drug Tolerance; Molsidomine; Nitric Oxide; Nitroglycerin; omega-N-Methylarginine; Rabbits; Trypsin; Vasodilation; Vasodilator Agents | 1991 |
Tumor necrosis factor and granulocyte macrophage-colony stimulating factor stimulate human macrophages to restrict growth of virulent Mycobacterium avium and to kill avirulent M. avium: killing effector mechanism depends on the generation of reactive nitr
Topics: Arginase; Arginine; Drug Synergism; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Immunity, Cellular; Interferon-gamma; Macrophages; Mycobacterium avium; Nitrites; omega-N-Methylarginine; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 1991 |
IFN-gamma inhibits development of Plasmodium berghei exoerythrocytic stages in hepatocytes by an L-arginine-dependent effector mechanism.
Topics: Animals; Arginine; Cells, Cultured; Interferon-gamma; Liver; Mice; Mice, Inbred BALB C; Nitrogen Oxides; omega-N-Methylarginine; Plasmodium berghei; Tumor Necrosis Factor-alpha | 1991 |
Macrophage cytostatic effect on Trypanosoma musculi involves an L-arginine-dependent mechanism.
Topics: Animals; Arginine; Female; Interferon-gamma; Iron; Macrophages; Mice; Mice, Inbred C57BL; Mycobacterium bovis; Nitric Oxide; Nitrites; omega-N-Methylarginine; Trypanosoma; Tumor Necrosis Factor-alpha | 1991 |
Cytokine interactions in experimental cutaneous leishmaniasis.
Topics: Animals; Arginine; Cells, Cultured; Drug Synergism; Female; Interferon-gamma; Interleukin-4; Leishmaniasis; Macrophage Activation; Macrophages; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Models, Biological; omega-N-Methylarginine; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1991 |
LTD4 and bradykinin evoke endothelium-dependent relaxation of the renal vein: dissimilar mechanisms.
Topics: Animals; Arginine; Benzopyrans; Bradykinin; Chromones; Cromakalim; Dogs; Endothelium, Vascular; Glyburide; Hemoglobins; Male; Methylene Blue; omega-N-Methylarginine; Pyrroles; Renal Veins; SRS-A; Vasodilation; Vasodilator Agents; Vasomotor System | 1991 |
Staphylococcal exotoxins stimulate nitric oxide-dependent murine macrophage tumoricidal activity.
Topics: Animals; Arginine; Bacterial Toxins; Cytotoxicity, Immunologic; Enterotoxins; Hydrogen Peroxide; Interferon-gamma; Lymphocyte Activation; Macrophages; Male; Mice; Mice, Inbred C3H; Nitric Oxide; omega-N-Methylarginine; Staphylococcus aureus; Superantigens; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1991 |
Mechanisms involved in mycobacterial growth inhibition by gamma interferon-activated bone marrow macrophages: role of reactive nitrogen intermediates.
Topics: Animals; Arginine; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Female; Hydrogen-Ion Concentration; Interferon-gamma; Lymphocyte Activation; Macrophages; Male; Mice; Mice, Inbred C57BL; Mycobacterium bovis; Nitrogen Oxides; omega-N-Methylarginine; Recombinant Proteins | 1991 |
Human endothelial cells are activated by IFN-gamma to inhibit Toxoplasma gondii replication. Inhibition is due to a different mechanism from that existing in mouse macrophages and human fibroblasts.
Topics: Animals; Arginine; Cytotoxicity, Immunologic; Endothelium, Vascular; Humans; Immunity, Cellular; In Vitro Techniques; Interferon-gamma; Nitric Oxide; omega-N-Methylarginine; Oxygen; Recombinant Proteins; Toxoplasma; Tryptophan | 1991 |
Nitric oxide: a potential mediator of amino acid-induced renal hyperemia and hyperfiltration.
Topics: Amino Acids; Animals; Arginine; Glomerular Filtration Rate; Glycine; Hemodynamics; Hyperemia; Infusions, Intravenous; Kidney; Kidney Diseases; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Renal Circulation | 1991 |
Effect of NG-monomethyl L-arginine (L-NMMA) and NG-nitro L-arginine (L-NOARG) on non-adrenergic non-cholinergic relaxation in the circular muscle of the human ileum.
Topics: Arginine; Dose-Response Relationship, Drug; Humans; Ileum; In Vitro Techniques; Muscle Relaxation; Nitroarginine; omega-N-Methylarginine | 1991 |
NG-monomethyl-L-arginine-induced pressor response at developmental and established stages in spontaneously hypertensive rats.
Topics: Acetylcholine; Aging; Animals; Arginine; Blood Pressure; Heart Rate; Injections, Intravenous; Male; omega-N-Methylarginine; Pressoreceptors; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Species Specificity | 1991 |
Endothelium-dependent relaxant effect of thrombocytin, a serine proteinase from Bothrops atrox snake venom, on isolated pig coronary arteries.
Topics: Animals; Arginine; Batroxobin; Coronary Vessels; Crotalid Venoms; Dinoprost; Endothelium, Vascular; Humans; In Vitro Techniques; Indomethacin; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; omega-N-Methylarginine; Platelet Aggregation; Serine Endopeptidases; Swine | 1991 |
Role of endothelium-derived relaxing factor in cerebral circulation: large arteries vs. microcirculation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Arginine; Arteries; Arterioles; Cerebrovascular Circulation; Male; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Inbred Strains | 1991 |
Effect of pregnancy on endothelium and smooth muscle: their role in reduced adrenergic sensitivity.
Topics: Animals; Arginine; Arteries; Calcimycin; Carotid Arteries; Endothelium, Vascular; Female; Guinea Pigs; Muscle, Smooth, Vascular; Nitroprusside; Norepinephrine; omega-N-Methylarginine; Pregnancy; Pregnancy, Animal; Uterus; Vasoconstriction; Vasodilation | 1991 |
NW-nitro L-arginine benzyl ester, a potent irreversible inhibitor of endothelium dependent relaxation.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Methylene Blue; Muscle, Smooth, Vascular; Nitroarginine; omega-N-Methylarginine; Phenylephrine; Rats; Rats, Inbred Strains; Vasoconstriction; Vasodilation | 1991 |
NG-monomethyl-L-arginine co-injection attenuates the thermogenic and hyperthermic effects of E2 prostaglandin microinjection into the anterior hypothalamic preoptic area in rats.
Topics: Animals; Arginine; Body Temperature; Body Temperature Regulation; Dinoprostone; Isomerism; Microinjections; omega-N-Methylarginine; Preoptic Area; Rats | 1991 |
Reduction of biological effluents in purge and trap micro reaction vessels and detection of endothelium-derived nitric oxide (edno) by chemiluminescence.
Topics: Animals; Arginine; Cattle; Endothelium, Vascular; Indomethacin; Luminescent Measurements; Nitric Oxide; omega-N-Methylarginine; Perfusion | 1991 |
Basal and acetylcholine-stimulated nitric oxide formation mediates relaxation of rabbit cavernous smooth muscle.
Topics: Acetylcholine; Animals; Arginine; Atropine Derivatives; Endothelium; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Parasympatholytics; Penis; Rabbits | 1991 |
Enhanced endothelium-derived relaxing factor activity in pregnant, spontaneously hypertensive rats.
Topics: Animals; Arginine; Blood Pressure; Female; Heart Rate; Indomethacin; Nitric Oxide; omega-N-Methylarginine; Pregnancy; Pregnancy, Animal; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1991 |
Glomerular nitrite synthesis in in situ immune complex glomerulonephritis in the rat.
Topics: Animals; Antigen-Antibody Complex; Arginine; Cells, Cultured; Dexamethasone; Glomerulonephritis; Hemodynamics; Immunoglobulin G; Kidney Glomerulus; Lipopolysaccharides; Macrophages; Male; Nitrites; omega-N-Methylarginine; Perfusion; Rats; Rats, Inbred Lew | 1991 |
Effect of arginine depletion on glomerular and tubular kidney function: studies in isolated perfused rat kidneys.
Topics: Animals; Arginine; Body Water; Citrulline; Glomerular Filtration Rate; Glucose; In Vitro Techniques; Kidney; Kidney Glomerulus; Kidney Tubules; Male; omega-N-Methylarginine; Ornithine; Perfusion; Rats; Rats, Inbred Strains; Sodium; Time Factors; Urine | 1991 |
Nitric oxide inhibition in rats improves blood pressure and renal function during hypovolemic shock.
Topics: Animals; Arginine; Blood Pressure; Glomerular Filtration Rate; Hemorrhage; Kidney; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Reference Values; Renal Circulation; Shock; Vascular Resistance | 1991 |
Endothelium-mediated regulation of coronary tone.
Topics: Acetylcholine; Animals; Arginine; Coronary Vessels; Dogs; Endothelium, Vascular; Heart; Hemodynamics; Muscle Tonus; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine | 1991 |
Release of nitric oxide from human vascular smooth muscle cells.
Topics: Animals; Arginine; Cells, Cultured; Humans; Kinetics; Luminescent Measurements; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Perfusion; Rats; Splanchnic Circulation | 1991 |
Role of nitric oxide in the genesis of excitatory amino acid-induced seizures from the deep prepiriform cortex.
Topics: Animals; Arginine; Electric Stimulation; Electroencephalography; Kainic Acid; Male; Methylene Blue; N-Methylaspartate; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Seizures; Temporal Lobe | 1991 |
Nitric oxide and vasoactive intestinal polypeptide mediate non-adrenergic, non-cholinergic inhibitory transmission to smooth muscle of the rat gastric fundus.
Topics: Animals; Arginine; Autonomic Nervous System; Electric Stimulation; Gastric Fundus; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Synaptic Transmission; Vasoactive Intestinal Peptide | 1990 |
Messengers mediating long-term desensitization in cerebellar Purkinje cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arginine; Cerebellum; Cyclic GMP; Egtazic Acid; Ibotenic Acid; In Vitro Techniques; omega-N-Methylarginine; Perfusion; Pertussis Toxin; Purkinje Cells; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Signal Transduction; Virulence Factors, Bordetella | 1990 |
EDRF release is a common pathway in the activation of guanylate cyclase by receptor agonists and calcium ionophores.
Topics: Arginine; Calcimycin; Calcium; Carbachol; Cells, Cultured; Cyclic GMP; Enzyme Activation; Guanylate Cyclase; Ionophores; Neuroblastoma; Nitric Oxide; omega-N-Methylarginine; Tumor Cells, Cultured | 1990 |
Endothelium-derived relaxing factor participates in the increased blood flow in response to pentagastrin in the rat stomach mucosa.
Topics: Animals; Arginine; Blood Pressure; Indomethacin; Intestinal Mucosa; Male; Nitric Oxide; omega-N-Methylarginine; Pentagastrin; Rats; Rats, Inbred Strains; Reference Values; Regional Blood Flow | 1990 |
Tumor necrosis factor alpha activates soluble guanylate cyclase in bovine glomerular mesangial cells via an L-arginine-dependent mechanism.
Topics: Animals; Arginine; Cattle; Cells, Cultured; Cyclic GMP; Cycloheximide; Dactinomycin; Enzyme Activation; Glomerular Mesangium; Guanylate Cyclase; Humans; Interferon-gamma; Interleukin-1; Kinetics; Nitrates; Nitrites; omega-N-Methylarginine; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1990 |
Peripheral analgesia and activation of the nitric oxide-cyclic GMP pathway.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Acetylcholine; Analgesia; Analgesics; Animals; Arginine; Cyclic GMP; Enzyme Activation; Guanylate Cyclase; Male; Nitric Oxide; Nociceptors; omega-N-Methylarginine; Rats; Rats, Inbred Strains | 1990 |
Non-adrenergic non-cholinergic relaxation mediated by nitric oxide in the canine ileocolonic junction.
Topics: Animals; Arginine; Autonomic Nervous System; Colon; Dogs; Electric Stimulation; Female; Hemoglobins; Ileum; Isometric Contraction; Male; Muscle Relaxation; Muscle, Smooth; Neurotransmitter Agents; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Stereoisomerism | 1990 |
Endothelium-derived relaxing factor inhibits hypoxic pulmonary vasoconstriction in rats.
Topics: Acetylcholine; Angiotensin II; Animals; Arginine; Blood Pressure; Dose-Response Relationship, Drug; Hypoxia; Male; Nitric Oxide; omega-N-Methylarginine; Pulmonary Artery; Pulmonary Circulation; Rats; Rats, Inbred Strains; Vasoconstriction | 1991 |
Nitric oxide production regulates alloactivation in rat splenocyte mixed lymphocyte cultures.
Topics: Animals; Arginine; Cells, Cultured; Cytotoxicity, Immunologic; Lymphocyte Activation; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred ACI; Rats, Inbred Lew; Spleen; T-Lymphocytes, Cytotoxic | 1991 |
L-arginine-dependent destruction of intrahepatic malaria parasites in response to tumor necrosis factor and/or interleukin 6 stimulation.
Topics: Animals; Arginine; Cells, Cultured; In Vitro Techniques; Interleukin-6; Liver; Nitrites; omega-N-Methylarginine; Plasmodium yoelii; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1991 |
Urinary nitrate excretion in relation to murine macrophage activation. Influence of dietary L-arginine and oral NG-monomethyl-L-arginine.
Topics: Animals; Arginine; Diet; Immunity, Innate; Macrophage Activation; Mice; Mycobacterium bovis; Nitrates; Nitrogen; omega-N-Methylarginine; Oxidation-Reduction; Time Factors; Tuberculosis | 1991 |
Role of prostaglandins and endothelium-derived relaxing factor on the renal response to acetylcholine.
Topics: Acetylcholine; Animals; Arginine; Dogs; Female; Hemodynamics; Kidney; Male; Nitric Oxide; omega-N-Methylarginine; Prostaglandins; Regional Blood Flow; Sodium | 1991 |
Acetylcholine-induced release of endothelium-derived relaxing factor from lymphatic endothelial cells.
Topics: Acetylcholine; Animals; Arginine; Aspirin; Atropine; Dogs; Endothelium; Female; Male; Methylene Blue; Muscle Relaxation; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Oxyhemoglobins; Thoracic Duct | 1991 |
Nitric oxide mediates the neurogenic vasodilation of bovine cerebral arteries.
Topics: Animals; Arginine; Cattle; Cerebral Arteries; Electric Stimulation; Endothelium, Vascular; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Superoxide Dismutase; Tetrodotoxin; Vasodilation | 1991 |
Suppression of lymphocyte proliferation through the nitric oxide synthesizing pathway.
Topics: Animals; Arginase; Arginine; Cell Adhesion; Cells, Cultured; Concanavalin A; Hemoglobins; In Vitro Techniques; Lymphocyte Activation; Lymphocytes; Mice; Nitric Oxide; Nitrites; omega-N-Methylarginine; Rats; Spleen; Urea | 1991 |
Effect of ouabain on endothelium-dependent relaxation of human resistance arteries.
Topics: Acetylcholine; Arginine; Arteries; Endothelium, Vascular; Female; Humans; Indomethacin; Male; Middle Aged; Nitroprusside; omega-N-Methylarginine; Ouabain; Vascular Resistance; Vasodilation | 1991 |
Activated macrophages kill pancreatic syngeneic islet cells via arginine-dependent nitric oxide generation.
Topics: Animals; Arginine; Cell Survival; Cells, Cultured; Immune Sera; Interleukin-1; Islets of Langerhans; Macrophage Activation; Macrophages; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1991 |
Impairment of endothelium-dependent pulmonary-artery relaxation in chronic obstructive lung disease.
Topics: Acetylcholine; Adenosine Diphosphate; Adolescent; Adult; Aged; Arginine; Endothelium, Vascular; Female; Humans; In Vitro Techniques; Lung Diseases, Obstructive; Male; Middle Aged; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Phenylephrine; Pulmonary Artery; Vasodilation | 1991 |
Effects of inhibition of nitric oxide formation on basal vasomotion and endothelium-dependent responses of the coronary arteries in awake dogs.
Topics: Acetylcholine; Animals; Arginine; Coronary Circulation; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Endothelium, Vascular; Hemodynamics; Nitric Oxide; omega-N-Methylarginine; Regional Blood Flow; Vasomotor System; Wakefulness | 1991 |
Mediatory role of endothelium-derived nitric oxide in renal vasodilatory and excretory effects of bradykinin.
Topics: Animals; Arginine; Bradykinin; Diuresis; Dogs; Female; Kidney; Male; Nitric Oxide; omega-N-Methylarginine; Renal Circulation; Vasodilation | 1991 |
Evidence that part of the NANC relaxant response of guinea-pig trachea to electrical field stimulation is mediated by nitric oxide.
Topics: Animals; Arginine; Autonomic Nervous System; Chymotrypsin; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Relaxation; Nitric Oxide; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Trachea; Vasoactive Intestinal Peptide | 1991 |
Effects of amino acid infusion on renal hemodynamics. Role of endothelium-derived relaxing factor.
Topics: Amino Acids; Animals; Arginine; Hemodynamics; Infusions, Intravenous; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Renal Circulation | 1991 |
Effect of NG-monomethyl L-arginine on endothelium-dependent relaxation in arterioles of one-kidney, one clip hypertensive rats.
Topics: Acetylcholine; Animals; Arginine; Arterioles; Bradykinin; Dose-Response Relationship, Drug; Endothelium, Vascular; Hypertension, Renovascular; Male; Nitroprusside; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Vasodilation | 1991 |
Inactivation of macrophage nitric oxide synthase activity by NG-methyl-L-arginine.
Topics: Animals; Arginine; Binding, Competitive; Bone Marrow; Kinetics; Macrophage Activation; Macrophages; Methemoglobin; Mice; Nitric Oxide; omega-N-Methylarginine; Oxyhemoglobins; Substrate Specificity; Urea | 1991 |
Effect of glycine on medullary thick ascending limb injury in perfused kidneys.
Topics: Amino Acids; Amphotericin B; Animals; Arginine; Glycine; Hypoxia; In Vitro Techniques; Indomethacin; Kidney Medulla; Kidney Tubules, Distal; Male; omega-N-Methylarginine; Oxygen Consumption; Perfusion; Rats; Rats, Inbred Strains | 1991 |
Nitric oxide requirement for vasomotor nerve-induced vasodilatation and modulation of resting blood flow in muscle microcirculation.
Topics: Animals; Arginine; Arterioles; Hindlimb; Male; Microcirculation; Muscles; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Rabbits; Regional Blood Flow; Vasodilation; Vasomotor System | 1991 |
L-arginine-dependent production of a reactive nitrogen intermediate by macrophages of a uricotelic species.
Topics: Animals; Arginine; Cell Line; Chickens; Female; Immunity; Macrophages; Nitric Oxide; Nitrites; omega-N-Methylarginine | 1991 |
Endothelium-derived and intraneuronal nitric oxide-dependent inhibition of norepinephrine efflux from sympathetic nerves by bradykinin.
Topics: Animals; Arginine; Bradykinin; Calcium; Canavanine; Dogs; Endothelium, Vascular; Female; Male; Neurons; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Physical Stimulation; Sympathetic Nervous System | 1991 |
Regional and cardiac haemodynamic effects of NG-nitro-L-arginine methyl ester in conscious, Long Evans rats.
Topics: Animals; Arginine; Blood Pressure; Coronary Circulation; Heart Rate; Hemodynamics; Male; NG-Nitroarginine Methyl Ester; omega-N-Methylarginine; Rats; Regional Blood Flow | 1990 |
Role of endothelium-derived nitric oxide in the regulation of tonus in large-bore arterial resistance vessels, arterioles and veins in cat skeletal muscle.
Topics: Animals; Arginine; Arteries; Arterioles; Cats; Endothelium, Vascular; Nitric Oxide; omega-N-Methylarginine; Vascular Resistance; Vasoconstriction; Veins | 1990 |
Role of nitric oxide in maintaining vascular integrity in endotoxin-induced acute intestinal damage in the rat.
Topics: Animals; Arginine; Blood Cell Count; Blood Pressure; Blood Vessels; Capillary Permeability; Endotoxins; Hemorrhage; Intestinal Diseases; Iodine Radioisotopes; Jejunum; Lipopolysaccharides; Male; Nitric Oxide; omega-N-Methylarginine; Phenylephrine; Rats; Rats, Inbred Strains | 1990 |
Rabbit brain contains an endogenous inhibitor of endothelium-dependent relaxation.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Brain Chemistry; Dialysis; Endothelium, Vascular; Hemoglobins; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nerve Tissue Proteins; Nitroarginine; omega-N-Methylarginine; Rabbits; Vasodilation | 1990 |
Pharmacological characterization of polycation-induced rat hind-paw oedema.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arginine; Azepines; Dexamethasone; Edema; Evans Blue; Heparin; Histamine; Indomethacin; Male; omega-N-Methylarginine; Peptides; Polylysine; Rats; Rats, Inbred Strains; Serotonin; Triazoles | 1990 |
Protective effect of S-nitroso-N-acetyl-penicillamine in endotoxin-induced acute intestinal damage in the rat.
Topics: Animals; Arginine; Blood Pressure; Endotoxins; Escherichia coli; Intestinal Diseases; Jejunum; Lipopolysaccharides; Male; omega-N-Methylarginine; Penicillamine; Rats; Rats, Inbred Strains; S-Nitroso-N-Acetylpenicillamine; Serum Albumin, Radio-Iodinated; Vasodilator Agents | 1990 |
Pressor effect of NG-monomethyl-L-arginine in SHRSP.
Topics: Animals; Arginine; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Injections, Intravenous; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1990 |
Tension-induced release of endothelium-derived relaxing factor; possible role in establishment of desensitization of norepinephrine-induced contraction in rat aorta.
Topics: Animals; Aorta, Thoracic; Arginine; Endothelium; Male; Myocardial Contraction; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Rats; Rats, Inbred Strains | 1990 |
An L-arginine-derived factor mediates endotoxin-induced vascular hyposensitivity to calcium.
Topics: Animals; Aorta, Thoracic; Arginine; Calcium; Endotoxins; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Vasoconstriction | 1990 |
Endothelial derived relaxing factor controls renal hemodynamics in the normal rat kidney.
Topics: Animals; Arginine; Hemodynamics; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Reference Values; Renal Circulation | 1990 |
Activated macrophages destroy intracellular Leishmania major amastigotes by an L-arginine-dependent killing mechanism.
Topics: Animals; Arginine; Cytotoxicity, Immunologic; Immunity, Cellular; Interferon-gamma; Leishmania tropica; Macrophage Activation; Macrophages; Male; Mice; Mice, Inbred C3H; Nitric Oxide; Nitrites; omega-N-Methylarginine | 1990 |
Regulation of gastric mucosal integrity by endogenous nitric oxide: interactions with prostanoids and sensory neuropeptides in the rat.
Topics: Animals; Arginine; Blood Pressure; Capsaicin; Epoprostenol; Gastric Mucosa; Indomethacin; Male; Neurons, Afferent; Neuropeptides; Nitric Oxide; omega-N-Methylarginine; Prostaglandins; Rats; Rats, Inbred Strains; Stomach Ulcer | 1990 |
Prostaglandins mediate arteriolar dilation to increased blood flow velocity in skeletal muscle microcirculation.
Topics: Acetylcholine; Animals; Arachidonic Acid; Arachidonic Acids; Arginine; Arteries; Arterioles; Blood Flow Velocity; Erythrocytes; Indomethacin; Male; Meclofenamic Acid; Microcirculation; Muscle, Smooth, Vascular; Muscles; omega-N-Methylarginine; Prostaglandins; Rats; Rats, Inbred Strains; Reference Values; Regional Blood Flow; Regression Analysis; Vasodilation | 1990 |
Alterations of ribonucleotide reductase activity following induction of the nitrite-generating pathway in adenocarcinoma cells.
Topics: Adenocarcinoma; Animals; Arginine; Cell Line; Dactinomycin; DNA Replication; Interferon-gamma; Interleukin-1; Kinetics; Lipopolysaccharides; Mammary Neoplasms, Experimental; Mice; Nitrites; omega-N-Methylarginine; Recombinant Proteins; Ribonucleotide Reductases; Thymidine; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1990 |
Mechanisms of macrophage-mediated tumor cell killing: a comparative analysis of the roles of reactive nitrogen intermediates and tumor necrosis factor.
Topics: Animals; Arginine; Argininosuccinic Acid; Cell Line; Cell Survival; Humans; Immunity, Cellular; Interferon-gamma; Macrophage Activation; Macrophages; Male; Mice; Neoplasms; Nitroarginine; omega-N-Methylarginine; Propionibacterium acnes; Rats; Tumor Necrosis Factor-alpha | 1990 |
Role of nitric oxide in regulation of basilar artery tone in vivo.
Topics: Acetylcholine; Animals; Arginine; Basilar Artery; Indomethacin; Male; Nitric Oxide; Nitroglycerin; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Serotonin | 1990 |
Impairment of endothelium-dependent dilatation of basilar artery during chronic hypertension.
Topics: Acetylcholine; Animals; Arginine; Basilar Artery; Bradykinin; Chronic Disease; Endothelium, Vascular; Hypertension; Indomethacin; Male; Nitroglycerin; omega-N-Methylarginine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasodilation | 1990 |
Production of an arginine-derived relaxing factor induced by IFN-gamma plus endotoxin in murine adenocarcinoma EMT 6 cells.
Topics: Adenocarcinoma; Aminoquinolines; Animals; Aorta, Thoracic; Arginine; Cell Division; Cell Line; Endotoxins; In Vitro Techniques; Interferon-gamma; Lipopolysaccharides; Male; Mice; Mice, Inbred BALB C; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Recombinant Proteins; SRS-A; Vasodilation | 1990 |
Nitric oxide is the endothelium-derived relaxing factor in bovine pial arterioles.
Topics: Acetylcholine; Animals; Arginine; Arterioles; Cattle; Endothelium, Vascular; Hemoglobins; Nitric Oxide; Nitroglycerin; omega-N-Methylarginine; Pia Mater; Vasoconstriction; Vasodilation | 1990 |
Protein kinases, nitric oxide and long-term depression of synapses in the cerebellum.
Topics: Animals; Arginine; Cerebellum; Evoked Potentials; In Vitro Techniques; Methylene Blue; Nitric Oxide; omega-N-Methylarginine; Polymyxin B; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Inbred Strains; Synapses | 1990 |
Alloantigen-induced activation of rat splenocytes is regulated by the oxidative metabolism of L-arginine.
Topics: Animals; Arginine; Citrulline; Cytotoxicity, Immunologic; Dose-Response Relationship, Drug; Immune Tolerance; In Vitro Techniques; Interleukin-2; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Macrophages; Mice; Nitrates; omega-N-Methylarginine; Phytohemagglutinins; Rats; T-Lymphocytes; T-Lymphocytes, Cytotoxic | 1990 |
Release of endothelin from the porcine aorta. Inhibition by endothelium-derived nitric oxide.
Topics: Animals; Aorta; Arginine; Calcimycin; Cyclic GMP; Endothelins; Endothelium, Vascular; In Vitro Techniques; Nitric Oxide; omega-N-Methylarginine; Peptide Biosynthesis; Peptides; Superoxide Dismutase; Swine; Thrombin | 1990 |
EPR demonstration of iron-nitrosyl complex formation by cytotoxic activated macrophages.
Topics: Animals; Arginine; Cells, Cultured; Citrulline; Electron Spin Resonance Spectroscopy; Female; Iron; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Mice, Inbred C3H; Mycobacterium bovis; Nitrogen; Nitrogen Oxides; omega-N-Methylarginine; Sulfur; Tuberculosis | 1990 |
Production of an EDRF-like activity in the cytosol of N1E-115 neuroblastoma cells.
Topics: Animals; Arginine; Cell-Free System; Cyclic GMP; Cytosol; Kinetics; Mice; Neuroblastoma; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Tumor Cells, Cultured | 1990 |
N omega-nitro-L-arginine: a potent inhibitor of endothelium-derived relaxing factor formation.
Topics: Adenosine Triphosphate; Animals; Arginine; Calcimycin; Cattle; Cyclic GMP; Depression, Chemical; Fibroblasts; In Vitro Techniques; Melitten; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Rats; Superoxide Dismutase | 1990 |
Role of endothelium-derived relaxing factor in regulation of renal hemodynamic responses.
Topics: Acetylcholine; Animals; Arginine; Blood Pressure; Cyclic GMP; Endothelium, Vascular; Hemodynamics; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Renal Circulation | 1990 |
Selective blockade of receptor-mediated cyclic GMP formation in N1E-115 neuroblastoma cells by an inhibitor of nitric oxide synthesis.
Topics: Animals; Arginine; Bradykinin; Carbachol; Cyclic GMP; Histamine; Mice; Neuroblastoma; Neurotensin; Nitric Oxide; omega-N-Methylarginine; Phosphatidylinositols; Receptors, Drug; Tumor Cells, Cultured | 1990 |
NG-methyl-L-arginine causes endothelium-dependent contraction and inhibition of cyclic GMP formation in artery and vein.
Topics: Acetylcholine; Animals; Arginine; Bradykinin; Cattle; Cyclic GMP; Endothelium, Vascular; In Vitro Techniques; Kinetics; Muscle, Smooth, Vascular; omega-N-Methylarginine; Oxyhemoglobins; Phenylephrine; Pulmonary Artery; Pulmonary Veins; Vasoconstriction | 1990 |
Possible role of nitric oxide in transmitting information from vasodilator nerve to cerebroarterial muscle.
Topics: Animals; Arginine; Cell Communication; Cerebral Arteries; Chemical Phenomena; Chemistry; Dogs; Electric Stimulation; Neuromuscular Junction; Nicotine; Nitric Oxide; omega-N-Methylarginine; Synaptic Transmission; Vasodilation | 1990 |
Effect of NG-monomethyl-L-arginine on endothelium-dependent relaxation of human subcutaneous resistance arteries.
Topics: Acetylcholine; Arginine; Arteries; Dose-Response Relationship, Drug; Endothelium; Female; Humans; In Vitro Techniques; Indomethacin; Male; Middle Aged; Nitric Oxide; Norepinephrine; omega-N-Methylarginine | 1990 |
Incubation with endotoxin activates the L-arginine pathway in vascular tissue.
Topics: Animals; Aorta, Thoracic; Arginine; Cyclic GMP; Endotoxins; In Vitro Techniques; Kinetics; Lipopolysaccharides; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Stereoisomerism | 1990 |
Evidence for the production of nitric oxide by activated macrophages treated with the antitumor agents flavone-8-acetic acid and xanthenone-4-acetic acid.
Topics: Animals; Antineoplastic Agents; Arginine; Cell Survival; Colonic Neoplasms; Dexamethasone; Flavonoids; Macrophages; Mice; Neoplasm Transplantation; Nitrates; Nitric Acid; Nitric Oxide; omega-N-Methylarginine; Xanthenes | 1990 |
NG-monomethyl L-arginine inhibits endothelium-derived relaxing factor-stimulated cyclic GMP accumulation in cocultures of endothelial and vascular smooth muscle cells by an action specific to the endothelial cell.
Topics: Adenosine Triphosphate; Animals; Arginine; Bradykinin; Calcimycin; Cattle; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Melitten; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Pulmonary Artery | 1990 |
Evidence for generation of a large amount of nitric oxide-like vascular smooth muscle relaxant by cholesterol-rich neutrophils.
Topics: Animals; Aorta; Arginine; Calcium; Cholesterol; Humans; In Vitro Techniques; Indomethacin; Kinetics; Liposomes; Muscle Relaxation; Muscle, Smooth, Vascular; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Oxyhemoglobins; Rats; Superoxides; Tetradecanoylphorbol Acetate | 1990 |
Tumor necrosis factor-alpha synergizes with IFN-gamma in mediating killing of Leishmania major through the induction of nitric oxide.
Topics: Animals; Arginine; Cytotoxicity, Immunologic; Drug Synergism; Hydrogen Peroxide; Immunity, Cellular; Interferon-gamma; Leishmania tropica; Leishmaniasis; Macrophages; Mice; Mice, Inbred CBA; Nitric Oxide; Nitrites; omega-N-Methylarginine; Superoxides; Tumor Necrosis Factor-alpha | 1990 |
Evidences for the existence of endothelium-derived relaxing factor in the renal medulla.
Topics: Acetylcholine; Animals; Arginine; Cyclic GMP; Dogs; Female; Kidney Medulla; Male; Molsidomine; Nitric Oxide; omega-N-Methylarginine; Premedication | 1990 |
L-arginine, but not N alpha-benzoyl-L-arginine ethyl ester, is a precursor of endothelium-derived relaxing factor.
Topics: Acetylcholine; Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Guinea Pigs; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitrates; Nitric Acid; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Pulmonary Artery | 1990 |
The effects of L-arginine and NG-monomethyl L-arginine on the inhibitory neurotransmission of the human corpus cavernosum penis.
Topics: Adult; Arginine; Electric Stimulation; Humans; In Vitro Techniques; Male; Middle Aged; Muscle Relaxation; omega-N-Methylarginine; Penis; Synaptic Transmission; Tetrodotoxin | 1990 |
Stimulation of cyclic GMP production in cultured endothelial cells of the pig by bradykinin, adenosine diphosphate, calcium ionophore A23187 and nitric oxide.
Topics: Adenosine Diphosphate; Animals; Arginine; Bradykinin; Calcimycin; Cells, Cultured; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; In Vitro Techniques; Kinetics; Methylene Blue; Nitric Oxide; omega-N-Methylarginine; Oxyhemoglobins; Stimulation, Chemical; Superoxide Dismutase; Superoxides; Swine | 1990 |
L-NG-monomethyl arginine inhibits the vasodilating effects of low dose of endothelin-3 on rat mesenteric arteries.
Topics: Animals; Arginine; Endothelins; Endothelium, Vascular; In Vitro Techniques; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Norepinephrine; omega-N-Methylarginine; Peptides; Perfusion; Pressure; Rats; Rats, Inbred Strains; Vasodilation | 1990 |
Kupffer cell:hepatocyte cocultures release nitric oxide in response to bacterial endotoxin.
Topics: Animals; Arginine; Cells, Cultured; Clostridium; Cytological Techniques; Endotoxins; Ferredoxins; Kupffer Cells; Lipopolysaccharides; Liver; Male; Nitric Oxide; omega-N-Methylarginine; Protein Biosynthesis | 1990 |
Loss of vascular responsiveness induced by endotoxin involves L-arginine pathway.
Topics: Acetylcholine; Animals; Aorta; Arginine; Blood Pressure; Endotoxins; Escherichia coli; In Vitro Techniques; Indomethacin; Lipopolysaccharides; Male; Methylene Blue; Norepinephrine; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Vasoconstriction | 1990 |
Inhibition of nitric oxide synthesis reduces the hypotension induced by bacterial lipopolysaccharides in the rat in vivo.
Topics: Anesthesia; Animals; Arginine; Blood Pressure; Escherichia coli; Lipopolysaccharides; Male; Nitric Oxide; omega-N-Methylarginine; Phenylephrine; Rats; Rats, Inbred Strains | 1990 |
Pharmacological differentiation of epithelium-derived relaxing factor from nitric oxide.
Topics: Animals; Arginine; Endothelium, Vascular; Guinea Pigs; Hemoglobins; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Nitric Oxide; omega-N-Methylarginine; Trachea | 1990 |
Modulation of nitrogen oxide synthesis in vivo: NG-monomethyl-L-arginine inhibits endotoxin-induced nitrate/nitrate biosynthesis while promoting hepatic damage.
Topics: Animals; Arginine; Female; Lipopolysaccharides; Liver; Mice; Mice, Inbred BALB C; Nitrates; Nitrites; Nitrogen Oxides; omega-N-Methylarginine; Propionibacterium acnes | 1990 |
Endothelium-dependent L-Arg- and L-NMMA-sensitive mechanisms regulate tone of brain microvessels.
Topics: Acetylcholine; Amino Acids; Animals; Arginine; Cerebrovascular Circulation; Endothelium, Vascular; Male; Mice; Mice, Inbred ICR; Microcirculation; Nitroprusside; omega-N-Methylarginine; Vasodilation | 1990 |
Role of endothelium-derived nitric oxide in the bleeding tendency of uremia.
Topics: Animals; Arginine; Bleeding Time; Calcimycin; Endothelium, Vascular; Hemorrhage; Male; Nitric Oxide; omega-N-Methylarginine; Platelet Adhesiveness; Platelet Aggregation; Rats; Rats, Inbred Strains; Uremia | 1990 |
Reversal of endotoxin-mediated shock by NG-methyl-L-arginine, an inhibitor of nitric oxide synthesis.
Topics: Animals; Arginine; Blood Pressure; Cytokines; Dogs; Endotoxins; Female; Hypertension; Kinetics; Male; Nitric Oxide; omega-N-Methylarginine; Shock, Septic; Vascular Resistance | 1990 |
Diet-induced atherosclerosis increases the release of nitrogen oxides from rabbit aorta.
Topics: Animals; Aorta; Arginine; Arteriosclerosis; Calcimycin; Cholesterol; Diet, Atherogenic; Luminescent Measurements; Nitric Oxide; Nitrogen Oxides; omega-N-Methylarginine; Rabbits; Time Factors | 1990 |
Role of endothelium-derived relaxing factor during transition of pulmonary circulation at birth.
Topics: Animals; Aorta; Arginine; Blood Pressure; Delivery, Obstetric; Fetus; Hemodynamics; Nitric Oxide; omega-N-Methylarginine; Pulmonary Circulation; Sheep; Vasodilation | 1990 |
Physiological release of nitric oxide is dependent on the level of vascular tone.
Topics: Acetylcholine; Animals; Arginine; Blood Pressure; Heart Rate; Male; Muscle Tonus; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Phenylephrine; Pressoreceptors; Rats; Rats, Inbred Strains | 1990 |
Tumour necrosis factor (TNF-alpha) in leishmaniasis. II. TNF-alpha-induced macrophage leishmanicidal activity is mediated by nitric oxide from L-arginine.
Topics: Animals; Arginine; Cytotoxicity, Immunologic; Leishmania tropica; Leishmaniasis; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred CBA; Nitric Oxide; omega-N-Methylarginine; Tumor Necrosis Factor-alpha | 1990 |
Regional haemodynamic changes during oral ingestion of NG-monomethyl-L-arginine or NG-nitro-L-arginine methyl ester in conscious Brattleboro rats.
Topics: Animals; Arginine; Blood Pressure; Heart Rate; Male; NG-Nitroarginine Methyl Ester; omega-N-Methylarginine; Rats; Rats, Brattleboro; Regional Blood Flow; Splanchnic Circulation | 1990 |
L-arginine and arginine analogues: effects on isolated blood vessels and cultured endothelial cells.
Topics: Animals; Arginine; Cattle; Citrulline; Endothelium, Vascular; Guanethidine; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nitrites; Nitrogen Oxides; omega-N-Methylarginine; Ornithine; Rabbits; Rats; Rats, Inbred Strains; Stereoisomerism; Swine | 1990 |
Inhibitory role of endothelium-derived relaxing factor in rat and human pulmonary arteries.
Topics: Acetylcholine; Animals; Arginine; Humans; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Phenylephrine; Potassium Chloride; Pulmonary Artery; Rats; Rats, Inbred Strains; Species Specificity; Stereoisomerism; Vasoconstriction | 1990 |
Modification by L-NG-monomethyl arginine (L-NMMA) of the response to nerve stimulation in isolated dog mesenteric and cerebral arteries.
Topics: Animals; Arginine; Blood Pressure; Cerebral Arteries; Dinoprost; Dogs; Electric Stimulation; In Vitro Techniques; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; omega-N-Methylarginine | 1990 |
Microbiostatic effect of murine-activated macrophages for Toxoplasma gondii. Role for synthesis of inorganic nitrogen oxides from L-arginine.
Topics: Animals; Arginine; Citrulline; Macrophage Activation; Macrophages; Mice; Mice, Inbred BALB C; Nitrates; Nitrites; Nitrogen Oxides; omega-N-Methylarginine; Toxoplasma | 1990 |
Endothelial cells metabolize NG-monomethyl-L-arginine to L-citrulline and subsequently to L-arginine.
Topics: Acetylcholine; Animals; Aorta; Aorta, Thoracic; Arginine; Cattle; Cells, Cultured; Citrulline; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Rabbits | 1990 |
L-NG-nitro arginine (L-NOARG), a novel, L-arginine-reversible inhibitor of endothelium-dependent vasodilatation in vitro.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Electric Stimulation; Endothelium, Vascular; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroarginine; Nitroprusside; Norepinephrine; omega-N-Methylarginine; Phenylephrine; Rabbits; Vasodilation | 1990 |
Effect of N alpha-benzoyl-L-arginine ethyl ester on coronary perfusion pressure in isolated guinea pig heart.
Topics: Animals; Arginine; Blood Pressure; Coronary Circulation; Guinea Pigs; Heart; Hemoglobins; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; omega-N-Methylarginine | 1990 |
Myogenic autoregulation of flow may be inversely related to endothelium-derived relaxing factor activity.
Topics: Animals; Arginine; Blood Pressure; Blood Vessels; Ear; Endothelium, Vascular; Hemoglobins; Homeostasis; In Vitro Techniques; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Perfusion; Rabbits; Regional Blood Flow; Rest; Vasoconstriction | 1990 |
Nitric oxide modulates epicardial coronary basal vasomotor tone in awake dogs.
Topics: Animals; Arginine; Coronary Vessels; Dogs; Hemodynamics; Nitric Oxide; omega-N-Methylarginine; Pericardium; Vasomotor System; Wakefulness | 1990 |
L-NG-monomethyl arginine and L-NG-nitro arginine inhibit non-adrenergic, non-cholinergic relaxation of the mouse anococcygeus muscle.
Topics: Animals; Arginine; Autonomic Nervous System; Electric Stimulation; In Vitro Techniques; Male; Mice; Muscle Relaxation; Muscles; Nitroarginine; omega-N-Methylarginine; Sympathetic Nervous System; Vasodilator Agents | 1990 |
Control of regional blood flow by endothelium-derived nitric oxide.
Topics: Animals; Arginine; Blood Circulation; Dose-Response Relationship, Drug; Drug Synergism; Endothelium, Vascular; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Regional Blood Flow | 1990 |
NG-methyl-L-arginine inhibits tumor necrosis factor-induced hypotension: implications for the involvement of nitric oxide.
Topics: Animals; Arginine; Blood Pressure; Dogs; Heart Rate; Hypotension; Nitric Oxide; omega-N-Methylarginine; Recombinant Proteins; Time Factors; Tumor Necrosis Factor-alpha | 1990 |
Inhibition of nitric oxide synthesis potentiates hypoxic vasoconstriction in isolated rat lungs.
Topics: Animals; Arginine; Hypoxia; Male; Nitric Oxide; omega-N-Methylarginine; Pulmonary Circulation; Pulmonary Wedge Pressure; Rats; Vasoconstriction | 1990 |
Effects of NG-monomethyl-L-arginine and L-arginine on acetylcholine renal response.
Topics: Acetylcholine; Animals; Arginine; Blood Pressure; Diuresis; Dogs; Female; Kidney; Male; Meclofenamic Acid; Nitric Oxide; omega-N-Methylarginine; Renal Circulation; Vasodilation | 1990 |
Macrophage killing of Leishmania parasite in vivo is mediated by nitric oxide from L-arginine.
Topics: Animals; Arginine; Immunity, Cellular; Leishmania tropica; Leishmaniasis; Macrophage Activation; Macrophages; Mice; Mice, Inbred CBA; Nitric Oxide; omega-N-Methylarginine | 1990 |
Influence of NG-monomethyl-L-arginine on endothelium-dependent relaxations in the perfused mesenteric vascular bed of the rat.
Topics: Acetylcholine; Animals; Arginine; Endothelium, Vascular; In Vitro Techniques; Mesenteric Arteries; Methylene Blue; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Vasodilation | 1990 |
Hyperpolarization and relaxation of arterial smooth muscle caused by nitric oxide derived from the endothelium.
Topics: Acetylcholine; Animals; Arginine; Calcium; Endothelium, Vascular; Female; Guinea Pigs; In Vitro Techniques; Membrane Potentials; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Signal Transduction; Uterus | 1990 |
Macrophage and endothelial cell nitric oxide synthesis: cell-type selective inhibition by NG-aminoarginine, NG-nitroarginine and NG-methylarginine.
Topics: Animals; Arginine; Blood Pressure; Cattle; Cells, Cultured; Endothelium, Vascular; Guinea Pigs; Macrophages; Mice; Nitric Oxide; Nitroarginine; omega-N-Methylarginine | 1990 |
Activation of endothelial L-arginine pathway in resistance arteries. Effect of age and hypertension.
Topics: Acetylcholine; Aging; Animals; Arginine; Endothelium, Vascular; Hypertension; Male; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Phenylephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vascular Resistance; Vasoconstriction | 1990 |
Role of nitric oxide in non-adrenergic, non-cholinergic nerve-mediated relaxation in dog duodenal longitudinal muscle strips.
Topics: Animals; Arginine; Autonomic Nervous System; Dogs; Duodenum; Electric Stimulation; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Oxyhemoglobins; Stereoisomerism | 1990 |
Pressor effect of endothelium-derived relaxing factor inhibition in conscious virgin and gravid rats.
Topics: Animals; Arginine; Blood Pressure; Female; Heart Rate; Nitric Oxide; omega-N-Methylarginine; Phenylephrine; Pregnancy; Pregnancy, Animal; Rats; Rats, Inbred Strains; Sexual Abstinence | 1990 |
Endogenous nitric oxide as a modulator of rabbit skeletal muscle microcirculation in vivo.
Topics: Acetylcholine; Adenosine; Animals; Arginine; Hyperemia; Leukocytes; Male; Microcirculation; Motor Neurons; Muscle Tonus; Muscle, Smooth, Vascular; Muscles; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Perfusion; Platelet Aggregation; Rabbits; Vasodilation | 1990 |
Nitric oxide release may be involved in the microcirculatory response to acetylcholine.
Topics: Acetylcholine; Animals; Arginine; Arterioles; In Vitro Techniques; Male; Microcirculation; Muscle Tonus; Muscle, Smooth; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Vasodilation | 1990 |
L-arginine is required for expression of the activated macrophage effector mechanism causing selective metabolic inhibition in target cells.
Topics: Aconitate Hydratase; Adenosine Diphosphate Ribose; Amino Acids; Animals; Arginase; Arginine; Cell Survival; Cells, Cultured; Culture Media; DNA; Guanidine; Guanidines; Homoarginine; Lipopolysaccharides; Macrophage Activation; Macrophages; Metabolism; Mice; Mitochondria; omega-N-Methylarginine; Oxidation-Reduction; Polyamines; Stereoisomerism; Structure-Activity Relationship | 1987 |
Modulation of the vasodepressor actions of acetylcholine, bradykinin, substance P and endothelin in the rat by a specific inhibitor of nitric oxide formation.
Topics: Acetylcholine; Animals; Arginine; Blood Pressure; Bradykinin; Endothelins; Epoprostenol; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitroglycerin; omega-N-Methylarginine; Peptides; Rats; Stereoisomerism; Substance P | 1989 |
Hypoxic pulmonary vasoconstriction is enhanced by inhibition of the synthesis of an endothelium derived relaxing factor.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Angiotensin II; Animals; Arginine; Blood Pressure; Bradykinin; Hypoxia; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Pulmonary Artery; Rats; Rats, Inbred Strains; Stereoisomerism; Vasoconstriction | 1989 |
Role of endothelium-derived nitric oxide in the regulation of blood pressure.
Topics: Acetylcholine; Animals; Arginine; Blood Pressure; Dose-Response Relationship, Drug; Endothelium, Vascular; Indomethacin; Kinetics; Male; Nitric Oxide; Nitroglycerin; omega-N-Methylarginine; Phenylephrine; Prazosin; Rabbits; Stereoisomerism; Vagotomy | 1989 |
Synthesis of nitric oxide from L-arginine by neutrophils. Release and interaction with superoxide anion.
Topics: Animals; Arginine; Blood Proteins; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitric Oxide; omega-N-Methylarginine; Platelet Aggregation; Rats; Rats, Inbred Strains; Superoxides | 1989 |
Inhibition of chemotaxis Ng-monomethyl-L-arginine: a role for cyclic GMP.
Topics: Arginine; Blood Bactericidal Activity; Chemotaxis, Leukocyte; Cyclic GMP; Dibutyryl Cyclic GMP; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Nitric Oxide; omega-N-Methylarginine | 1989 |
A kainate receptor linked to nitric oxide synthesis from arginine.
Topics: Animals; Arginine; Cerebellum; Cyclic GMP; In Vitro Techniques; Kainic Acid; Kinetics; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Receptors, Kainic Acid; Receptors, Neurotransmitter | 1989 |
Cyclic GMP stimulation by vasopressin in LLC-PK1 kidney epithelial cells is L-arginine-dependent.
Topics: Arginine; Calcimycin; Cell Line; Cyclic GMP; Epithelial Cells; Kidney; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Vasopressins | 1989 |
Evidence for a role of nitric oxide in the neurotransmitter system mediating relaxation of the rat anococcygeus muscle.
Topics: Animals; Arginine; Autonomic Nervous System; Electric Stimulation; In Vitro Techniques; Male; Muscle Relaxation; Muscles; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Stereoisomerism; Synaptic Transmission | 1989 |
Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum.
Topics: Animals; Arginine; Aspartic Acid; Cerebellum; Citrulline; Cyclic GMP; Glutamates; Glutamic Acid; Hemoglobins; In Vitro Techniques; Kainic Acid; Kinetics; N-Methylaspartate; Nitric Oxide; omega-N-Methylarginine; Oxadiazoles; Quisqualic Acid; Rats | 1989 |
Regulation of macrophage physiology by L-arginine: role of the oxidative L-arginine deiminase pathway.
Topics: Animals; Arginine; Cell Survival; Cells, Cultured; Electron Transport; Hydrolases; Macrophages; Male; Mice; Nitrites; omega-N-Methylarginine; Peritoneal Cavity; Rats; Rats, Inbred F344 | 1989 |
Kupffer cell cytotoxicity to hepatocytes in coculture requires L-arginine.
Topics: Animals; Arginine; Aspartate Aminotransferases; Cell Survival; Cells, Cultured; Citrulline; Infections; Kupffer Cells; Lipopolysaccharides; Liver; Male; Nitrates; Nitrites; omega-N-Methylarginine; Protein Biosynthesis; Rats; Rats, Inbred Strains | 1989 |
The effects of L-arginine and NG-monomethyl L-arginine on the response of the rat anococcygeus muscle to NANC nerve stimulation.
Topics: Animals; Arginine; Autonomic Nervous System; Electric Stimulation; In Vitro Techniques; Male; Muscles; omega-N-Methylarginine; Rats | 1989 |
NG-monomethyl L-arginine is a non-specific inhibitor of vascular relaxation.
Topics: Animals; Aorta, Thoracic; Arginine; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth, Vascular; omega-N-Methylarginine; Rats | 1989 |
Nitric oxide synthesised from L-arginine mediates endothelium dependent dilatation in human veins in vivo.
Topics: Adult; Arginine; Hand; Humans; Middle Aged; Nitric Oxide; omega-N-Methylarginine; Vasodilation; Veins | 1989 |
The vasodilator role of endogenous nitric oxide in the rat gastric microcirculation.
Topics: Animals; Arginine; Blood Pressure; Dose-Response Relationship, Drug; Gastric Mucosa; In Vitro Techniques; Microcirculation; Nitric Oxide; omega-N-Methylarginine; Rats; Regional Blood Flow; Vasodilation | 1989 |
Effects of NG-monomethyl-L-arginine on field stimulation-induced decreases in cytosolic Ca2+ levels and relaxation in the rat anococcygeus muscle.
Topics: Animals; Arginine; Calcium; Clonidine; Cytosol; Electric Stimulation; In Vitro Techniques; Male; Muscle Relaxation; Muscles; omega-N-Methylarginine; Rats; Rats, Inbred Strains | 1989 |
The cytosol of N1E-115 neuroblastoma cells synthesizes an EDRF-like substance that relaxes rabbit aorta.
Topics: Animals; Aorta, Thoracic; Arginine; Cytosol; Female; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth, Vascular; Neuroblastoma; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Rabbits; Superoxide Dismutase; Tumor Cells, Cultured | 1989 |
L-arginine independent macrophage tumor cytotoxicity.
Topics: Animals; Arginine; Chromium Radioisotopes; Cytotoxicity, Immunologic; Glucose; Iron Radioisotopes; Leukemia L1210; Macrophage Activation; Macrophages; Mycobacterium bovis; Neoplasms; omega-N-Methylarginine; Tumor Cells, Cultured | 1989 |
NG-monomethyl-L-arginine does not inhibit the hindquarters vasodilator action of endothelin-1 in conscious rats.
Topics: Animals; Arginine; Blood Pressure; Endothelins; Heart Rate; Hindlimb; Male; Nitric Oxide; omega-N-Methylarginine; Peptides; Rats; Regional Blood Flow | 1989 |
NG-methylarginine, an inhibitor of endothelium-derived nitric oxide synthesis, is a potent pressor agent in the guinea pig: does nitric oxide regulate blood pressure in vivo?
Topics: Angiotensin II; Animals; Arginine; Blood Pressure; Endothelium, Vascular; Guinea Pigs; Heart Rate; Injections, Intravenous; Male; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Premedication; Vasoconstrictor Agents | 1989 |
L-arginine availability determines the duration of acetylcholine-induced systemic vasodilation in vivo.
Topics: Acetylcholine; Animals; Arginine; Biological Availability; Blood Pressure; Depression, Chemical; Guinea Pigs; Male; Nitric Oxide; omega-N-Methylarginine; Time Factors; Vasodilation | 1989 |
Nitric oxide synthesized from L-arginine regulates vascular tone in the coronary circulation of the rabbit.
Topics: Acetylcholine; Animals; Arginine; Coronary Circulation; Heart; In Vitro Techniques; Luminescent Measurements; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Rabbits; Superoxide Dismutase | 1989 |
A specific inhibitor of nitric oxide formation from L-arginine attenuates endothelium-dependent relaxation.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Endothelium, Vascular; In Vitro Techniques; Male; Nitric Oxide; omega-N-Methylarginine; Rabbits; Stereoisomerism; Vasodilation | 1989 |
Synthesis of NG-monomethylagmatine, a decarboxylation product of NG-monomethyl-L-arginine.
Topics: Agmatine; Arginine; Decarboxylation; Euglena gracilis; Guanidines; Magnetic Resonance Spectroscopy; Mass Spectrometry; omega-N-Methylarginine; Putrescine | 1987 |
Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production.
Topics: Animals; Arginine; Biological Factors; Cytokines; Drug Synergism; Female; Free Radicals; Hydrogen Peroxide; Interferon Type I; Interferon-gamma; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Nitrates; omega-N-Methylarginine; Peritoneal Cavity; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1988 |
Identification of arginine as a precursor of endothelium-derived relaxing factor.
Topics: Acetylcholine; Animals; Arginine; Biological Factors; Endothelium, Vascular; Guinea Pigs; Histamine; In Vitro Techniques; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Pulmonary Artery; Vasodilation; Vasodilator Agents | 1988 |
Metabolism of NG-monomethyl-L-arginine.
Topics: Animals; Arginase; Arginine; Carbon Radioisotopes; Cattle; Colorimetry; Hydrolysis; Kidney; Manganese; Methylurea Compounds; omega-N-Methylarginine; Rats | 1983 |
Metabolism of NG-monomethyl-L-arginine: formation of NG-methylagmatine by Escherichia coli preparation.
Topics: Agmatine; Arginine; Escherichia coli; Guanidines; Magnetic Resonance Spectroscopy; Methylation; omega-N-Methylarginine; Ornithine Decarboxylase | 1981 |
Cerebellar nitric oxide is necessary for vestibulo-ocular reflex adaptation, a sensorimotor model of learning.
Topics: Adaptation, Ocular; Animals; Arginine; Cerebellum; Electromagnetic Fields; Enzyme Inhibitors; Goldfish; Histocytochemistry; Learning; Models, Neurological; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Reflex, Vestibulo-Ocular | 1995 |
Nitric oxide as a retrograde messenger in the nucleus tractus solitarii of rats during hypoxia.
Topics: Animals; Arginine; Citrulline; Dizocilpine Maleate; Drug Combinations; Enzyme Inhibitors; Glutamic Acid; Hypercapnia; Hypoxia; Male; Microinjections; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Osmolar Concentration; Rats; Rats, Sprague-Dawley; Respiration; Solitary Nucleus | 1995 |
Effect of nitric oxide synthase inhibition on bleeding time in humans.
Topics: Adult; Arginine; Bleeding Time; Blood Platelets; Female; Forearm; Humans; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Adhesiveness; Platelet Aggregation; Regional Blood Flow | 1995 |
Tumor necrosis factor-alpha and nitric oxide production in endotoxin-primed rats administered carbon tetrachloride.
Topics: Alanine Transaminase; Animals; Arginine; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Dexamethasone; Electron Spin Resonance Spectroscopy; Endotoxins; Enzyme Inhibitors; Escherichia coli; Gadolinium; Kinetics; L-Iditol 2-Dehydrogenase; L-Lactate Dehydrogenase; Liver; Macrophage Activation; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 1995 |
Polyarginine and eosinophil-derived major basic protein increase microvascular permeability independently of histamine or nitric oxide release.
Topics: Animals; Arginine; Blood Proteins; Capillary Permeability; Cell Degranulation; Cheek; Cricetinae; Dextrans; Enzyme Inhibitors; Eosinophil Granule Proteins; Fluorescein-5-isothiocyanate; Histamine H1 Antagonists; Histamine Release; Inflammation Mediators; Male; Mast Cells; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Peptides; Pyrilamine; Ribonucleases | 1995 |
Intrauterine hypoxia-ischemia increases N-methyl-D-aspartate-induced cGMP formation and glutamate accumulation in cultured rat cerebellar granule cells.
Topics: Animals; Arginine; Brain Ischemia; Cells, Cultured; Cerebellar Diseases; Chronic Disease; Cyclic GMP; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Fetal Hypoxia; Gestational Age; Glutamic Acid; Hypoxia, Brain; Kainic Acid; N-Methylaspartate; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley | 1995 |
Nitric oxide inhibits the release of norepinephrine and dopamine from the medial basal hypothalamus of the rat.
Topics: Animals; Arginine; Dopamine; Enzyme Inhibitors; Feedback; Gonadotropin-Releasing Hormone; Hypothalamus, Middle; In Vitro Techniques; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Norepinephrine; omega-N-Methylarginine; Rats; Rats, Wistar; Secretory Rate | 1995 |
Nitric oxide synthase pathway may mediate human natural killer cell cytotoxicity.
Topics: Arginine; Cells, Cultured; Cytotoxicity, Immunologic; Enzyme Inhibitors; Humans; Killer Cells, Natural; Nitric Oxide Synthase; omega-N-Methylarginine | 1995 |
Nitric oxide: a cytokine-induced regulator of bone resorption.
Topics: Animals; Arginine; Base Sequence; Bone Resorption; Calcium; Cytokines; Dinoprostone; DNA Primers; Drug Synergism; Enzyme Inhibitors; Humans; Interferon-gamma; Interleukin-1; Mice; Molecular Sequence Data; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Organ Culture Techniques; Osteoclasts; Penicillamine; Polymerase Chain Reaction; Recombinant Proteins; RNA; S-Nitroso-N-Acetylpenicillamine; Tumor Necrosis Factor-alpha | 1995 |
Insulin resistance after hypertension induced by the nitric oxide synthesis inhibitor L-NMMA in rats.
Topics: Animals; Arginine; Blood Glucose; Glucose; Glycogen; Hypertension; Insulin; Insulin Resistance; Liver; Male; Muscle, Skeletal; Nitric Oxide Synthase; omega-N-Methylarginine; Osmolar Concentration; Rats; Rats, Sprague-Dawley | 1995 |
Flow-dependent arteriolar dilation in normotensive rats fed low- or high-salt diets.
Topics: Acetylcholine; Animals; Arachidonic Acid; Arginine; Arterioles; Blood Pressure; Diet, Sodium-Restricted; Male; Meclofenamic Acid; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Reference Values; Regional Blood Flow; Sodium Chloride, Dietary; Time Factors; Vasodilation | 1995 |
Nicotinamide inhibits IRF-1 mRNA induction and prevents IL-1 beta-induced nitric oxide synthase expression in pancreatic beta cells.
Topics: Adenosine Triphosphate; Animals; Arginine; Base Sequence; Benzamides; Cell Survival; DNA Primers; DNA-Binding Proteins; Enzyme Induction; Gene Expression; Glucose; Interferon Regulatory Factor-1; Interleukin-1; Islets of Langerhans; Male; Mice; Molecular Sequence Data; Niacinamide; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phosphoproteins; Poly Adenosine Diphosphate Ribose; Polymerase Chain Reaction; Rats; Rats, Wistar; Recombinant Proteins; RNA, Messenger; Transcription Factors | 1995 |
Direct measurement of nitric oxide production in platelets: relationship with cytosolic Ca2+ concentration.
Topics: Adenosine Diphosphate; Arginine; Blood Platelets; Calcium; Cytosol; Humans; In Vitro Techniques; Kinetics; Nitric Oxide; omega-N-Methylarginine; Potentiometry; Stereoisomerism; Thrombin | 1995 |
NG-monomethyl-L-arginine, an inhibitor of nitric oxide synthase, increases extracellular GABA in the striatum of the freely moving rat.
Topics: Animals; Arginine; Enzyme Inhibitors; Extracellular Space; GABA Agonists; gamma-Aminobutyric Acid; Male; Microdialysis; Neostriatum; Neurotransmitter Agents; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Wistar; Tetrodotoxin | 1995 |
The role of nitric oxide in hemodynamic and metabolic alterations induced by prostaglandin F2 alpha in the perfused rat liver.
Topics: Animals; Arginine; Bile; Dinoprost; Endotoxins; Enzyme Inhibitors; Escherichia coli; Glucose; Hemodynamics; Kinetics; Lactates; Lactic Acid; Liver; Male; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Perfusion; Rats; Rats, Wistar; Urea | 1995 |
A cellular mechanism for nitric oxide-mediated cholinergic control of mammalian heart rate.
Topics: 1-Methyl-3-isobutylxanthine; Aminoquinolines; Animals; Arginine; Carbachol; Cardiotonic Agents; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Enzyme Inhibitors; GTP-Binding Proteins; Guanylate Cyclase; Heart Rate; Isoproterenol; Methylene Blue; Molsidomine; Muscarinic Agonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Aggregation Inhibitors; Rabbits; Receptors, Cholinergic; Receptors, Muscarinic; Sinoatrial Node; Thionucleotides | 1995 |
Barium and strontium can substitute for calcium in stimulating nitric oxide production in the endothelium of canine coronary arteries.
Topics: Animals; Arginine; Barium; Calcium; Cations, Divalent; Coronary Vessels; Cyclic GMP; Dogs; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Isometric Contraction; Muscle Relaxation; Neurotransmitter Agents; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Potassium; Strontium | 1995 |
K+ channel blockers do not modify relaxation of guinea-pig uterine artery evoked by acetylcholine.
Topics: Acetylcholine; Animals; Arginine; Arteries; Diethylcarbamazine; Drug Interactions; Female; Guinea Pigs; In Vitro Techniques; Indomethacin; Isotonic Solutions; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; omega-N-Methylarginine; Potassium Channels; Uterus | 1995 |
Platelet-activating factor-induced loss of vascular responsiveness to noradrenaline in pithed rats: involvement of nitric oxide.
Topics: Analysis of Variance; Animals; Arginine; Cyclooxygenase Inhibitors; Decerebrate State; Enzyme Inhibitors; Indomethacin; Male; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; omega-N-Methylarginine; Platelet Activating Factor; Rats; Rats, Wistar; Vasomotor System | 1995 |
Reactive nitrogen intermediates implicated in the inhibition of Encephalitozoon cuniculi (phylum microspora) replication in murine peritoneal macrophages.
Topics: Animals; Arginine; Cells, Cultured; Encephalitozoon cuniculi; Female; Interferon-gamma; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Nitric Oxide; omega-N-Methylarginine; Recombinant Proteins | 1995 |
The role of nitric oxide in enteropathy.
Topics: Animals; Arginine; Disease Models, Animal; Enzyme Inhibitors; Graft vs Host Reaction; Hyperplasia; Hypertrophy; Intestinal Diseases; Intestinal Mucosa; Mice; Nitric Acid; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Spleen; Transplantation, Homologous | 1995 |
Role of nitric oxide in adenosine receptor-mediated relaxation of porcine coronary artery.
Topics: Aminoquinolines; Animals; Arginine; Coronary Vessels; Cyclic GMP; Male; Nitric Oxide; Nitrites; omega-N-Methylarginine; Receptors, Purinergic P1; Swine; Vasodilation; Vasodilator Agents | 1995 |
Endothelium-dependent relaxation is depressed at the macro- and microcirculatory levels during sepsis.
Topics: Acetylcholine; Animals; Aorta; Arginine; Endothelium, Vascular; In Vitro Techniques; Infections; Intestine, Small; Male; Mesenteric Arteries; Microcirculation; Nitric Oxide Synthase; Nitroglycerin; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Vascular Resistance; Vasodilation | 1995 |
A selective agonist of endothelin type B receptor, IRL 1620, stimulates cyclic GMP increase via nitric oxide formation in rat aorta.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Aorta, Thoracic; Arginine; Binding Sites; Calcium; Cyclic GMP; Cytosol; Drug Interactions; Endothelins; Endothelium, Vascular; Kinetics; Male; Membranes; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Peptide Fragments; Peptides, Cyclic; Rats; Rats, Wistar; Receptors, Endothelin; Stimulation, Chemical; Time Factors | 1993 |
Nitric oxide and nitric oxide synthase mRNA induction in mouse islet cells by interferon-gamma plus tumor necrosis factor-alpha.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Base Sequence; Cells, Cultured; Cycloheximide; Cytokines; Enzyme Induction; Interferon-gamma; Islets of Langerhans; Mice; Molecular Sequence Data; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; RNA, Messenger; Tumor Necrosis Factor-alpha | 1993 |
Platelet adhesion to human vascular endothelium is modulated by constitutive and cytokine induced nitric oxide.
Topics: Amino Acid Oxidoreductases; Arginine; Cells, Cultured; Cytokines; Dexamethasone; Endothelium, Vascular; Humans; Interleukin-1; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Adhesiveness; Stimulation, Chemical; Tumor Necrosis Factor-alpha | 1993 |
Inhibitors of nitric oxide synthase enhance rat ileum contractions induced by ricinoleic acid in vitro.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Drug Synergism; Ileum; In Vitro Techniques; Male; Muscle Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Wistar; Ricinoleic Acids; Tetrodotoxin | 1993 |
Receptor mechanism of thrombin-induced endothelium-dependent and endothelium-independent coronary vascular effects in dogs.
Topics: Amino Acid Chloromethyl Ketones; Amino Acid Oxidoreductases; Amino Acid Sequence; Animals; Arginine; Arteries; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Endothelium, Vascular; Hemoglobins; In Vitro Techniques; Male; Molecular Sequence Data; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide Synthase; omega-N-Methylarginine; Peptide Fragments; Receptors, Thrombin; Thrombin | 1993 |
Effect of nitric oxide synthase substrate analog inhibitors on rat liver arginase.
Topics: Amino Acid Oxidoreductases; Animals; Arginase; Arginine; Kinetics; Liver; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats | 1993 |
IL-1 beta induces the coexpression of both nitric oxide synthase and cyclooxygenase by islets of Langerhans: activation of cyclooxygenase by nitric oxide.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Dactinomycin; Dinoprostone; Enzyme Activation; In Vitro Techniques; Interleukin-1; Islets of Langerhans; Kinetics; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley | 1993 |
Molecular evidence for nitric oxide-mediated motor neuron development.
Topics: Amino Acid Oxidoreductases; Animals; Animals, Newborn; Arginine; Cellular Senescence; Humans; Molecular Biology; Motor Neurons; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Spinal Cord; Tissue Distribution | 1993 |
Long-term depression requires nitric oxide and guanosine 3':5' cyclic monophosphate production in rat cerebellar Purkinje cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amino Acid Oxidoreductases; Animals; Arginine; Cyclic GMP; In Vitro Techniques; Long-Term Potentiation; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Purkinje Cells; Rats; Time Factors | 1993 |
Inhibition of nitric oxide formation by guanidines.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Cell Line; Guanidines; In Vitro Techniques; Interleukin-1; Male; Mesenteric Arteries; Methylguanidine; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Vasoconstriction | 1993 |
Impaired nitric oxide-dependent cyclic guanosine monophosphate generation in glomeruli from diabetic rats. Evidence for protein kinase C-mediated suppression of the cholinergic response.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alkaloids; Amino Acid Oxidoreductases; Animals; Arginine; Calcimycin; Carbachol; Cyclic GMP; Diabetes Mellitus, Experimental; Female; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Isoquinolines; Kidney Glomerulus; Kinetics; Membrane Proteins; Myristoylated Alanine-Rich C Kinase Substrate; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phosphates; Phosphorylation; Piperazines; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Proteins; Rats; Rats, Sprague-Dawley; Staurosporine; Thromboxane A2 | 1994 |
Nitric oxide release from porcine mitral valves.
Topics: Adenosine Diphosphate; Amino Acid Oxidoreductases; Animals; Arginine; Biological Assay; Bradykinin; Calcimycin; Calcium; Culture Techniques; Endocardium; Endothelium; Epithelium; Mitral Valve; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Substance P; Swine; Thrombin | 1993 |
Human retinal pigmented epithelial cells produce nitric oxide in response to cytokines.
Topics: Amino Acid Oxidoreductases; Arginine; Cells, Cultured; Cycloheximide; Cytokines; Fibroblast Growth Factor 2; Humans; Interferon-gamma; Interleukin-1; Kinetics; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; omega-N-Methylarginine; Pigment Epithelium of Eye; Recombinant Proteins; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 1994 |
Laminar flow stimulates ATP- and shear stress-dependent nitric oxide production in cultured bovine endothelial cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Animals; Aorta, Thoracic; Arginine; Calcium; Cattle; Cells, Cultured; Cyclic GMP; Egtazic Acid; Endothelium, Vascular; Fetus; Kinetics; Nitric Oxide; omega-N-Methylarginine; Stress, Mechanical | 1994 |
Inhibitors of brain nitric oxide synthase. Binding kinetics, metabolism, and enzyme inactivation.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Brain; Chromatography, Gel; Kinetics; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Regression Analysis; Swine | 1994 |
The role of nitric oxide in the pathogenesis of spontaneous murine autoimmune disease: increased nitric oxide production and nitric oxide synthase expression in MRL-lpr/lpr mice, and reduction of spontaneous glomerulonephritis and arthritis by orally admi
Topics: Administration, Oral; Amino Acid Oxidoreductases; Animals; Arginine; Arthritis; Autoimmune Diseases; Chromosome Mapping; Crosses, Genetic; Female; Glomerulonephritis; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine | 1994 |
Inducible L-arginine-dependent nitric oxide synthase activity in bovine bone marrow-derived macrophages.
Topics: Amino Acid Oxidoreductases; Animals; Arginase; Arginine; Bacterial Physiological Phenomena; Bone Marrow Cells; Cattle; Enzyme Induction; Interferon-gamma; Macrophage Activation; Macrophages; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Tumor Necrosis Factor-alpha | 1994 |
Selective inhibition of basal but not agonist-stimulated activity of nitric oxide in rat aorta by NG-monomethyl-L-arginine.
Topics: Acetylcholine; Amino Acid Oxidoreductases; Animals; Aorta; Arginine; Endothelium, Vascular; Female; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Phenylephrine; Rats; Rats, Wistar; Sensitivity and Specificity; Stimulation, Chemical | 1993 |
The induction of nitric oxide synthase and intestinal vascular permeability by endotoxin in the rat.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Capillary Permeability; Colon; Dexamethasone; Endotoxins; Enzyme Induction; Escherichia coli; Jejunum; Lipopolysaccharides; Male; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Wistar | 1993 |
Aminoguanidine selectively inhibits inducible nitric oxide synthase.
Topics: Acetylcholine; Amino Acid Oxidoreductases; Animals; Arginine; Cimetidine; Endothelium, Vascular; Endotoxins; Enzyme Induction; Guanidines; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide Synthase; omega-N-Methylarginine; Phenylephrine; Pulmonary Artery; Pyrilamine; Rats; Rats, Wistar | 1993 |
Interrelationship of changes in islet nicotine adeninedinucleotide, insulin secretion, and cell viability induced by interleukin-1 beta.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Arginine Vasopressin; beta-Endorphin; Cell Survival; Cells, Cultured; Colforsin; Corticosterone; Dynorphins; Glucose; Insulin; Insulin Secretion; Interleukin-1; Islets of Langerhans; Kinetics; Male; NAD; Niacinamide; Nitric Oxide Synthase; omega-N-Methylarginine; Probucol; Progesterone; Rats; Vitamin E | 1994 |
Effects of sodium-transport inhibition in human resistance arteries.
Topics: Arginine; Biological Transport, Active; Bufanolides; Chlormadinone Acetate; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Ouabain; Potassium; Sodium; Sodium-Potassium-Exchanging ATPase; Vascular Resistance | 1993 |
Inducible nitric oxide synthase activity in hepatocytes is dependent on the coinduction of tetrahydrobiopterin synthesis.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Biopterins; Cells, Cultured; Cytokines; Enzyme Induction; Gene Expression; GTP Cyclohydrolase; Hypoxanthines; Lipopolysaccharides; Liver; Methotrexate; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; RNA, Messenger | 1993 |
Modulation of glomerular arteriolar tone by nitric oxide synthase inhibitors.
Topics: Acetylcholine; Amino Acid Oxidoreductases; Animals; Arginine; Arterioles; Dinoprostone; Dopamine; Female; In Vitro Techniques; Kidney Glomerulus; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Norepinephrine; omega-N-Methylarginine; Rabbits; Renal Circulation; Vasodilation | 1993 |
Role of NO production in NMDA receptor-mediated neurotransmitter release in cerebral cortex.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cerebral Cortex; Glutamates; Glutamic Acid; Guinea Pigs; In Vitro Techniques; Indazoles; Male; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Norepinephrine; omega-N-Methylarginine; Potassium Chloride; Receptors, N-Methyl-D-Aspartate; Synaptosomes | 1994 |
[NO-synthase inhibition induces a resistant pressor reaction during the 10-minute intravenous infusion of angiotensin-2 to narcotized rats].
Topics: Amino Acid Oxidoreductases; Angiotensin II; Animals; Arginine; Blood Pressure; Dose-Response Relationship, Drug; Female; Infusions, Intravenous; Nitric Oxide Synthase; omega-N-Methylarginine; Pentobarbital; Rats; Time Factors | 1993 |
Induction of iron-derived EPR signals in murine cancers by nitric oxide. Evidence for multiple intracellular targets.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cytokines; Electron Spin Resonance Spectroscopy; Interferon-gamma; Interleukin-1; Iron; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Neoplasms, Experimental; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1994 |
Inhibition of nitric oxide synthase in experimental gram-negative sepsis.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Escherichia coli; Escherichia coli Infections; Liver; Mice; Nitrates; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Shock, Septic; Tumor Necrosis Factor-alpha | 1994 |
Nitric oxide produced during murine listeriosis is protective.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Female; Listeriosis; Male; Mice; Mice, Inbred C57BL; Nitrates; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; RNA, Messenger | 1994 |
Induction of nitric oxide synthase by cyclic AMP in rat vascular smooth muscle cells.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Amino Acid Oxidoreductases; Animals; Aorta, Thoracic; Arginine; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Cycloheximide; Dactinomycin; Dexamethasone; Enzyme Induction; Kinetics; Muscle, Smooth, Vascular; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Wistar; RNA, Ribosomal | 1994 |
Endothelin (ET)-3 stimulates cyclic guanosine 3',5'-monophosphate production via ETB receptor by producing nitric oxide in isolated rat glomerulus, and in cultured rat mesangial cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Calmodulin; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Egtazic Acid; Endothelin Receptor Antagonists; Endothelins; Glomerular Mesangium; Guanylate Cyclase; Hemoglobins; In Vitro Techniques; Kidney Glomerulus; Kinetics; Male; Methylene Blue; Nicardipine; Nitric Oxide; omega-N-Methylarginine; Peptide Fragments; Peptides, Cyclic; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; Sulfonamides | 1994 |
Induction of nitric oxide release by interferon-gamma inhibits vasodilation and cyclic GMP increase in bovine isolated mesenteric arteries.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Cattle; Cyclic GMP; In Vitro Techniques; Interferon-gamma; Mesenteric Arteries; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Vasodilation | 1994 |
Phenylephrine-induced rhythmic activity in the rabbit ear artery.
Topics: Animals; Arginine; Arteries; Charybdotoxin; Ear, External; Endothelium, Vascular; Glyburide; In Vitro Techniques; Indomethacin; Male; Nifedipine; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Periodicity; Phenylephrine; Potassium Channel Blockers; Prostaglandin Antagonists; Rabbits; Scorpion Venoms; Vasoconstriction | 1993 |
[The autoregulation of the coronary flow of the isolated rat heart after NO-synthase blockade].
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Flow Velocity; Coronary Circulation; Female; Homeostasis; In Vitro Techniques; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Perfusion; Pituitary Hormones, Posterior; Rats | 1993 |
Nitric oxide and human skin blood flow responses to acetylcholine and ultraviolet light.
Topics: Acetylcholine; Adult; Amino Acid Oxidoreductases; Arginine; Humans; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Prostaglandin-Endoperoxide Synthases; Regional Blood Flow; Skin; Ultraviolet Rays | 1994 |
NG-monomethyl-L-ARG reduces the forearm vasodilator response to acetylcholine but not to methacholine in humans.
Topics: Acetylcholine; Adolescent; Adult; Arginine; Blood Pressure; Forearm; Humans; Infusions, Intravenous; Male; Methacholine Chloride; Nitric Oxide; omega-N-Methylarginine; Plethysmography; Regional Blood Flow; Vasodilation | 1993 |
Endothelin-1 and aggregation of human platelets in vitro.
Topics: Adult; Arginine; Blood Platelets; Endothelins; Humans; In Vitro Techniques; Male; Nitric Oxide; omega-N-Methylarginine; Platelet Aggregation | 1993 |
Cellular mechanism of endothelin-induced nitric oxide synthesis by cultured bovine endothelial cells.
Topics: Animals; Arginine; Calcium; Calmodulin; Cattle; Cells, Cultured; Egtazic Acid; Endothelins; Endothelium, Vascular; Nitric Oxide; omega-N-Methylarginine; Sulfonamides | 1993 |
Venoconstriction to endothelin-1 in humans is attenuated by local generation of prostacyclin but not nitric oxide.
Topics: Adult; Amino Acid Oxidoreductases; Arginine; Aspirin; Endothelins; Epoprostenol; Hand; Humans; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroglycerin; omega-N-Methylarginine; Regional Blood Flow; Vasoconstriction | 1993 |
Regulation of endothelin-1 expression in normal and transfected endothelial cells.
Topics: Animals; Arginine; Blotting, Northern; Cattle; Cell Line; DNA, Complementary; Down-Regulation; Endothelin-1; Endothelins; Endothelium, Vascular; Humans; Nitric Oxide; omega-N-Methylarginine; Oximes; Penicillamine; Plasmids; Protein Precursors; Retroviridae; S-Nitroso-N-Acetylpenicillamine; Superoxide Dismutase; Transfection; Up-Regulation | 1993 |
Inhibitory effect of nitric oxide (NO) synthase inhibitors on naloxone-precipitated withdrawal syndrome in morphine-dependent mice.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Behavior, Animal; Diarrhea; Male; Mice; Morphine Dependence; Naloxone; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Substance Withdrawal Syndrome | 1993 |
Effects of NG-methyl-L-arginine, NG-nitro-L-arginine, and aminoguanidine on constitutive and inducible nitric oxide synthase in rat aorta.
Topics: Amino Acid Oxidoreductases; Animals; Aorta; Arginine; Enzyme Induction; Guanidines; Lipopolysaccharides; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Structure-Activity Relationship | 1994 |
Nitric oxide synthase inhibition with NG-mono-methyl-L-arginine reversibly decreases cerebral blood flow in piglets.
Topics: Amino Acid Oxidoreductases; Analysis of Variance; Animals; Arginine; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Infusions, Intravenous; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Prospective Studies; Random Allocation; Swine; Time Factors | 1994 |
A nitric oxide synthase inhibitor reduces desensitisation of bradykinin-induced activation of phospholipase C in sensory neurones.
Topics: Amino Acid Oxidoreductases; Animals; Animals, Newborn; Arginine; Bradykinin; Bucladesine; Cells, Cultured; Enzyme Activation; Ganglia, Spinal; Inositol Phosphates; Kinetics; Neurons, Afferent; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Rats; Second Messenger Systems; Type C Phospholipases | 1993 |
Tumor necrosis factor-alpha (TNF-alpha), interferon-gamma, and interleukin-6 but not TNF-beta induce differentiation of neuroblastoma cells: the role of nitric oxide.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Differentiation; DNA; Interferon-gamma; Interleukin-6; Lymphotoxin-alpha; Mice; Neuroblastoma; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Recombinant Proteins; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1994 |
Is endotoxin-induced hypotension related to nitric oxide formation?
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Dogs; Endotoxins; Hemodynamics; Hypotension; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Oxygen; Random Allocation; Shock, Septic; Tumor Necrosis Factor-alpha | 1994 |
Effect of local inhibition of nitric oxide synthesis on forearm blood flow and dorsal hand vein size in patients with alcoholic cirrhosis.
Topics: Adult; Aged; Amino Acid Oxidoreductases; Arginine; Dose-Response Relationship, Drug; Female; Forearm; Hand; Humans; Liver Cirrhosis, Alcoholic; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; omega-N-Methylarginine; Regional Blood Flow; Vasodilation; Veins | 1994 |
Smooth muscle cell responsiveness to nitrovasodilators in hypertensive and normotensive rats.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Base Sequence; Blotting, Northern; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Guanylate Cyclase; Hypertension; Male; Molecular Sequence Data; Muscle, Smooth, Vascular; Nitric Oxide; Nitroglycerin; Nitroprusside; Oligonucleotide Probes; omega-N-Methylarginine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA, Messenger; Vasodilation | 1994 |
Argininosuccinate synthetase mRNA and activity are induced by immunostimulants in vascular smooth muscle. Role in the regeneration or arginine for nitric oxide synthesis.
Topics: Adjuvants, Immunologic; Amino Acid Oxidoreductases; Animals; Aorta, Thoracic; Arginine; Argininosuccinate Synthase; Base Sequence; Cells, Cultured; Citrulline; Cycloheximide; Cytosol; Dactinomycin; Dexamethasone; DNA Primers; Enzyme Induction; Interferon-gamma; Kinetics; Lipopolysaccharides; Molecular Sequence Data; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Polymerase Chain Reaction; Rats; Rats, Inbred F344; Recombinant Proteins; RNA, Messenger | 1994 |
Interleukin-4 stimulates cGMP production by IFN-gamma-activated human monocytes. Involvement of the nitric oxide synthase pathway.
Topics: Amino Acid Oxidoreductases; Aminoquinolines; Arginine; Calcium; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Egtazic Acid; Guanylate Cyclase; Humans; Interferon-gamma; Interleukin-4; Kinetics; Leukocytes, Mononuclear; Methylene Blue; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine | 1994 |
Induction of nitric oxide synthase in human mammary arteries in vitro.
Topics: Amino Acid Oxidoreductases; Arginine; Endothelium, Vascular; Enzyme Induction; Glucocorticoids; Humans; In Vitro Techniques; Mammary Arteries; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Phenylephrine | 1994 |
NADPH-diaphorase activity of nitric oxide synthase in the olfactory bulb: co-factor specificity and characterization regarding the interrelation to NO formation.
Topics: 2,6-Dichloroindophenol; Amino Acid Oxidoreductases; Animals; Arginine; Cytochrome c Group; Egtazic Acid; Immunohistochemistry; Male; Miconazole; NADPH Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase; Olfactory Bulb; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Staining and Labeling; Substrate Specificity; Trifluoperazine | 1994 |
Modulatory influence of putative inhibitors of nitric oxide synthesis on visual processing in the cat lateral geniculate nucleus.
Topics: Amino Acid Oxidoreductases; Anesthesia; Animals; Arginine; Cats; Geniculate Bodies; Iontophoresis; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Photic Stimulation; Visual Perception | 1994 |
Nitric oxide mediates suppression of cartilage proteoglycan synthesis by interleukin-1.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cartilage, Articular; Cells, Cultured; Glycosaminoglycans; Humans; Interleukin-1; Kinetics; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Penicillamine; Proteins; Proteoglycans; Rabbits; Recombinant Proteins; S-Nitroso-N-Acetylpenicillamine; Stereoisomerism; Sulfates | 1994 |
Role of nitric oxide in the pathogenesis of early pancreatic islet dysfunction during rat and human intraportal islet transplantation.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Glucose; Humans; Islets of Langerhans Transplantation; Liver; Nitrates; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Portal System; Rats; Rats, Inbred Lew; Transplantation, Heterotopic | 1994 |
Involvement of nitric oxide and cyclic GMP in rabbit urethral relaxation.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Canavanine; Cyclic GMP; Electric Stimulation; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rabbits; Urethra | 1994 |
Nitric oxide synthase inhibition blocks tolerance to the analgesic action of kappa-opiate receptor agonist in the rat.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Amino Acid Oxidoreductases; Analgesics; Animals; Arginine; Body Temperature; Body Weight; Drug Tolerance; Male; Nitric Oxide Synthase; omega-N-Methylarginine; Pain Measurement; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa | 1994 |
Selective targeting of nitric oxide synthase inhibitors to system y+ in activated macrophages.
Topics: Amino Acid Oxidoreductases; Amino Acid Transport Systems; Animals; Arginine; Biological Transport, Active; Canavanine; Carrier Proteins; Cell Line; Citrulline; Lipopolysaccharides; Macrophage Activation; Macrophages; Membrane Glycoproteins; Membrane Proteins; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Ornithine; Receptors, Virus | 1994 |
Nitric oxide regulates basal systemic and pulmonary vascular resistance in healthy humans.
Topics: Adult; Amino Acid Oxidoreductases; Arginine; Blood Pressure; Cardiac Output; Female; Humans; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phenylephrine; Pulmonary Artery; Pulmonary Circulation; Pulmonary Wedge Pressure; Vascular Resistance | 1994 |
Induction of nitric oxide synthase in subsets of murine pulmonary fibroblasts: effect on fibroblast interleukin-6 production.
Topics: Amino Acid Oxidoreductases; Animals; Antigens, Surface; Arginine; Base Sequence; Cell Line; Cytokines; Enzyme Induction; Fibroblasts; Guanidines; Interleukin-6; Lung; Membrane Glycoproteins; Mice; Molecular Sequence Data; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; RNA, Messenger; Thy-1 Antigens | 1994 |
Nitric oxide as a messenger molecule for myoblast fusion.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Fusion; Cells, Cultured; Chick Embryo; Chickens; Creatine Kinase; Kinetics; Methylene Blue; Muscles; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Second Messenger Systems; Time Factors | 1994 |
Nitric oxide inhibits indoleamine 2,3-dioxygenase activity in interferon-gamma primed mononuclear phagocytes.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cells, Cultured; Diethylamines; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Kinetics; Leukocytes, Mononuclear; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitrogen Oxides; Nitroprusside; omega-N-Methylarginine; Oxyhemoglobins; Penicillamine; Phagocytes; Recombinant Proteins; S-Nitroso-N-Acetylpenicillamine; Tryptophan Oxygenase | 1994 |
Endogenous nitric oxide enhances prostaglandin production in a model of renal inflammation.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cholic Acids; Dinoprostone; Disease Models, Animal; Hydronephrosis; In Vitro Techniques; Indomethacin; Kidney; Male; Models, Biological; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Perfusion; Prostaglandin-Endoperoxide Synthases; Rabbits; Ureter | 1994 |
The effects of NG-nitro-L-arginine, a nitric oxide synthase inhibitor, on norepinephrine overflow and antidiuresis induced by stimulation of renal nerves in anesthetized dogs.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Diuresis; Dogs; Electric Stimulation; Female; Kidney; Male; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; omega-N-Methylarginine; Sympathetic Nervous System; Vasoconstriction | 1994 |
Tonic regulation of mouse ileal ion transport by nitric oxide.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Ileum; In Vitro Techniques; Ion Transport; Male; Membrane Potentials; Mice; Mice, Inbred ICR; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Sodium Nitrite | 1994 |
Production of angiogenic activity by human monocytes requires an L-arginine/nitric oxide-synthase-dependent effector mechanism.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cells, Cultured; Chemotaxis; Cornea; Culture Media, Conditioned; Endothelium, Vascular; Endotoxins; Humans; Interleukin-8; Lipopolysaccharides; Monocytes; Neovascularization, Pathologic; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Stereoisomerism; Tumor Necrosis Factor-alpha; Umbilical Veins | 1994 |
Nitric oxide mediates the stimulation of luteinizing-hormone releasing hormone release induced by glutamic acid in vitro.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Glutamates; Glutamic Acid; Gonadotropin-Releasing Hormone; Hemoglobins; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Stimulation, Chemical | 1994 |
Reversibility of interleukin-1 beta-induced islet destruction and dysfunction by the inhibition of nitric oxide synthase.
Topics: Aconitate Hydratase; Amino Acid Oxidoreductases; Animals; Arginine; Dactinomycin; Insulin; Insulin Secretion; Interleukin-1; Iron; Islets of Langerhans; Male; Nitric Oxide Synthase; omega-N-Methylarginine; Oxidation-Reduction; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley | 1994 |
Impaired endothelium-dependent vasodilation in patients with essential hypertension: evidence that the abnormality is not at the muscarinic receptor level.
Topics: Acetylcholine; Arginine; Endothelium, Vascular; Female; Forearm; Humans; Hypertension; Male; Middle Aged; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Receptors, Muscarinic; Substance P; Vasodilation | 1994 |
Effects of guanidino and uremic compounds on nitric oxide pathways.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Line; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Guanidines; Humans; Macrophages; Mice; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Saphenous Vein | 1994 |
Characterization of an inhibitor of nitric oxide synthase in human-hand veins.
Topics: Adult; Amino Acid Oxidoreductases; Arginine; Bradykinin; Hand; Humans; Male; Methylene Blue; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phenylephrine; Regional Blood Flow; Vascular Resistance; Vasodilation; Veins | 1994 |
N omega -monomethyl-L-arginine inhibits nitric oxide production in murine cardiac allografts but does not affect graft rejection.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Graft Rejection; Heart Transplantation; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Time Factors; Transplantation, Homologous | 1994 |
Platelets increase the tone of quiescent rat aortic rings by release of serotonin and potentiate the subsequent contractile response to norepinephrine.
Topics: Amino Acid Oxidoreductases; Animals; Aorta, Thoracic; Apyrase; Arginine; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Endothelium, Vascular; Ergolines; Fatty Acids, Unsaturated; Hydrazines; In Vitro Techniques; Male; Muscle Contraction; Muscle Tonus; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Norepinephrine; omega-N-Methylarginine; Platelet Aggregation; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Antagonists; Thromboxane A2 | 1994 |
Epicardial and endocardial coronary microvascular responses: effects of ischemia-reperfusion.
Topics: Adenosine; Animals; Arginine; Bradykinin; Calcimycin; Coronary Circulation; Endocardium; Endothelium, Vascular; Female; Glyburide; Guanylate Cyclase; Indomethacin; Male; Microcirculation; Muscle, Smooth, Vascular; Nitroprusside; omega-N-Methylarginine; Reperfusion Injury; Serotonin; Swine | 1994 |
Predominant role for nitric oxide in the relaxation induced by acetylcholine in human uterine artery.
Topics: Acetylcholine; Adult; Amino Acid Oxidoreductases; Arginine; Arteries; Endothelium, Vascular; Female; Humans; Methylene Blue; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Papaverine; Phenylephrine; Tetraethylammonium; Tetraethylammonium Compounds; Uterus; Vasodilation | 1994 |
Human osteoblast-like cells produce nitric oxide and express inducible nitric oxide synthase.
Topics: Amino Acid Oxidoreductases; Arginine; Base Sequence; Cells, Cultured; Cyclic GMP; Cytokines; Enzyme Induction; Humans; Molecular Probes; Molecular Sequence Data; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Osteoblasts; Polymerase Chain Reaction; Time Factors; Transcription, Genetic | 1994 |
A functional role for nitric oxide in locus coeruleus: immunohistochemical and electrophysiological studies.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acid Oxidoreductases; Animals; Arginine; Electric Stimulation; Electrophysiology; Evoked Potentials; Hemoglobins; Immunohistochemistry; In Vitro Techniques; Locus Coeruleus; Male; Microscopy, Electron; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Quinoxalines; Rats; Rats, Sprague-Dawley; Synapses; Synaptic Transmission; Tyrosine 3-Monooxygenase | 1994 |
Modification of striatal arginine and citrulline metabolism by nitric oxide synthase inhibitors.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Citrulline; Corpus Striatum; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley | 1994 |
Evidence that nitric oxide is an endogenous antiangiogenic mediator.
Topics: Allantois; Animals; Arginine; Chick Embryo; Chorion; Cyclic GMP; Dexamethasone; Drug Interactions; Endothelium, Vascular; Humans; Models, Biological; Neovascularization, Pathologic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Thrombin | 1994 |
Nitric oxide mediates sexual behavior in female rats.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cerebral Ventricles; Estradiol; Female; Gonadotropin-Releasing Hormone; Hypothalamus; Immune Sera; Injections, Intraventricular; Isomerism; Male; Microinjections; Models, Neurological; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Ovariectomy; Posture; Progesterone; Rats; Rats, Sprague-Dawley; Sexual Behavior, Animal | 1994 |
N-monomethyl arginine, an inhibitor of nitric oxide synthase, suppresses the development of adjuvant arthritis in rats.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Arthritis, Experimental; Disease Models, Animal; Male; Nitrates; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Rats; Rats, Inbred Lew | 1994 |
Hypoxic coronary vasodilatation and cGMP overproduction are blocked by a nitric oxide synthase inhibitor, but not by a guanylyl cyclase ANF receptor antagonist.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Atrial Natriuretic Factor; Coronary Circulation; Cyclic GMP; Guanylate Cyclase; Guinea Pigs; Humans; Hypoxia; In Vitro Techniques; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Perfusion; Polysaccharides; Receptors, Atrial Natriuretic Factor; Vasodilation | 1994 |
Time-dependent enhancement or inhibition of endotoxin-induced vascular injury in rat intestine by nitric oxide synthase inhibitors.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Endothelium, Vascular; Intestines; Lipopolysaccharides; Male; Microcirculation; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Wistar; Time Factors | 1994 |
Expression of nitric oxide synthase in rat glomerular mesangial cells mediated by cyclic AMP.
Topics: Adenylyl Cyclases; Amino Acid Oxidoreductases; Animals; Antimetabolites; Arginine; Blotting, Northern; Cells, Cultured; Citrulline; Cyclic AMP; Cytosol; Enzyme Activation; Glomerular Mesangium; Interleukin-1; Kinetics; Nitrates; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; RNA, Messenger; Tumor Necrosis Factor-alpha; Up-Regulation | 1994 |
Metabolism of methylarginines by human vasculature; implications for the regulation of nitric oxide synthesis.
Topics: Amino Acid Oxidoreductases; Arginase; Arginine; Cells, Cultured; Chromatography, High Pressure Liquid; Citrulline; Cytosol; Endothelium, Vascular; Humans; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Saphenous Vein; Umbilical Veins | 1994 |
Comparative effects of NG-monomethyl-L-arginine and MK-801 on the abstinence syndrome in morphine-dependent mice.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Dizocilpine Maleate; Male; Mice; Morphine Dependence; Naltrexone; Nitric Oxide Synthase; omega-N-Methylarginine; Receptors, N-Methyl-D-Aspartate | 1994 |
Insulin increases guanosine-3',5'-cyclic monophosphate in human platelets. A mechanism involved in the insulin anti-aggregating effect.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Diphosphate; Adult; Amino Acid Oxidoreductases; Arginine; Blood Platelets; Collagen; Cyclic GMP; Female; Genistein; Guanylate Cyclase; Humans; Insulin; Isoflavones; Male; Methylene Blue; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein-Tyrosine Kinases; Radioimmunoassay; Recombinant Proteins | 1994 |
Nitric oxide participates in the regulation of pancreatic acinar cell secretion.
Topics: Amino Acid Oxidoreductases; Amylases; Animals; Arginine; Carbachol; Cyclic AMP; In Vitro Techniques; Male; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; omega-N-Methylarginine; Pancreas; Rats; Rats, Wistar | 1994 |
The role of nitric oxide in the kainate-induced seizures in mice.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Dose-Response Relationship, Drug; Kainic Acid; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Seizures | 1994 |
Uptake of nitric oxide synthase inhibitors by macrophage RAW 264.7 cells.
Topics: Amino Acid Oxidoreductases; Amino Acid Transport Systems; Animals; Arginine; Biological Transport; Carrier Proteins; Cell Line; Interferon-gamma; Leucine; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Recombinant Proteins; Sodium | 1994 |
[Effect of endogenous metabolites on autoregulation and dilational reserve of coronary vessels].
Topics: Amino Acid Oxidoreductases; Angiotensin II; Animals; Arginine; Captopril; Coronary Circulation; Coronary Vessels; Eicosanoids; Female; In Vitro Techniques; Indomethacin; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Vasodilation; Verapamil | 1993 |
Delayed gastric emptying induced by inhibitors of nitric oxide synthase in rats.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Gastric Emptying; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley | 1994 |
Nitric oxide-mediated inhibition of the mitochondrial respiratory chain in cultured astrocytes.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Astrocytes; Catalase; Cells, Cultured; Egtazic Acid; Electron Transport; Electron Transport Complex IV; Interferon-gamma; Lipopolysaccharides; Mitochondria; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Wistar; Superoxide Dismutase | 1994 |
Possible role of nitric oxide in catecholamine secretion by chromaffin cells in the presence and absence of cultured endothelial cells.
Topics: Adrenal Medulla; Amino Acid Oxidoreductases; Animals; Arginine; Catecholamines; Cattle; Cells, Cultured; Chromaffin System; Dimethylphenylpiperazinium Iodide; Endothelium, Vascular; Guanylate Cyclase; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Potassium | 1994 |
Release of nitric oxide during the experimental infection with Trypanosoma cruzi.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Base Sequence; Chagas Disease; Disease Models, Animal; DNA Primers; Female; Interferon-gamma; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Peritoneal Cavity; RNA, Messenger; Spleen; Trypanosoma cruzi; Virulence | 1994 |
Is nitric oxide involved in cutaneous vasodilation during body heating in humans?
Topics: Acetylcholine; Adolescent; Adult; Amino Acid Oxidoreductases; Arginine; Blood Pressure; Female; Forearm; Hot Temperature; Humans; Infusions, Intra-Arterial; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Plethysmography; Regional Blood Flow; Skin; Sweating; Vasodilation | 1994 |
Short-term daily exercise activity enhances endothelial NO synthesis in skeletal muscle arterioles of rats.
Topics: Acetylcholine; Amino Acid Oxidoreductases; Animals; Arginine; Arterioles; Body Weight; Endothelium, Vascular; Male; Muscles; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Organ Size; Physical Conditioning, Animal; Rats; Rats, Wistar; Regional Blood Flow | 1994 |
Increase by NO synthase inhibitors of acetylcholine release from guinea-pig myenteric plexus.
Topics: Acetylcholine; Amino Acid Oxidoreductases; Animals; Arginine; Electric Stimulation; Evoked Potentials; Guinea Pigs; Muscle, Smooth; Myenteric Plexus; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine | 1994 |
Hepatocyte inducible nitric oxide synthesis is influenced in vitro by cell density.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Biopterins; Cell Count; Cells, Cultured; Cyclic GMP; Cytokines; Humans; Lipopolysaccharides; Liver; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1994 |
Expression of inducible nitric oxide in human lung epithelial cells.
Topics: Amino Acid Oxidoreductases; Arginine; Blotting, Northern; Bronchi; Cell Line; Cells, Cultured; Cytokines; Dexamethasone; Enzyme Induction; Epithelium; Gene Expression; Humans; Kinetics; Lung; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Recombinant Proteins; Trachea; Tumor Necrosis Factor-alpha | 1994 |
Vasoconstrictor responses after neo-intima formation and endothelial removal in the rabbit carotid artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Angiotensin I; Angiotensin II; Animals; Arginine; Carotid Arteries; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Neovascularization, Pathologic; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Potassium Chloride; Prostaglandin Endoperoxides, Synthetic; Rabbits; Serotonin; Thromboxane A2; Vasoconstriction; Vasoconstrictor Agents | 1994 |
Evidence for differential roles of nitric oxide (NO) and hyperpolarization in endothelium-dependent relaxation of pig isolated coronary artery.
Topics: Animals; Arginine; Coronary Vessels; Endothelium, Vascular; Female; In Vitro Techniques; Isometric Contraction; Male; Membrane Potentials; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Potassium; Substance P; Swine | 1994 |
"Upstream" modification of vasoconstrictor responses in rat epigastric artery supplying an implanted tumour.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Arteries; In Vitro Techniques; Neoplasm Transplantation; Nitric Oxide Synthase; omega-N-Methylarginine; Phenylephrine; Rats; Rats, Inbred Strains; Sarcoma, Experimental; Vasoconstriction | 1994 |
Hippocampal in vitro kindling is not blocked by nitric oxide synthase inhibitors.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cyclic GMP; Electric Stimulation; Hippocampus; In Vitro Techniques; Kindling, Neurologic; Long-Term Potentiation; Male; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Synapses; Synaptic Transmission | 1994 |
Cyclic guanosine monophosphate is the mediator of platelet-activating factor inhibition on transport by the mouse kidney thick ascending limb.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Calcium; Chlorides; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Isoquinolines; Kidney Medulla; Kinetics; Loop of Henle; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Parathyroid Hormone; Platelet Activating Factor; Protein Kinase C; Time Factors; Vasopressins | 1994 |
Evidence that histamine is involved as a mediator of endothelium-dependent contraction induced by A23187 in bovine intrapulmonary vein.
Topics: Animals; Arginine; Atropine; Calcimycin; Cattle; Cromolyn Sodium; Endothelins; Endothelium, Vascular; Hemoglobins; Histamine; Histamine H1 Antagonists; Histamine Release; In Vitro Techniques; Iproniazid; Methylene Blue; Muscle Contraction; Muscle, Smooth, Vascular; omega-N-Methylarginine; p-Methoxy-N-methylphenethylamine; Pulmonary Veins; Thioxanthenes; Xanthones | 1994 |
Role of superoxide dismutase and nitric oxide on the interaction between brain and systemic circulation during brain ischemia.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Circulation; Blood Pressure; Brain Ischemia; Carotid Arteries; Cerebrovascular Circulation; Frontal Lobe; Magnetic Resonance Imaging; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Polystyrenes; Rats; Rats, Wistar; Superoxide Dismutase; Survival Analysis | 1994 |
Inhibition of nitric oxide production is associated with enhanced weight loss, decreased survival, and impaired alloengraftment in mice undergoing graft-versus-host disease after bone marrow transplantation.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Body Weight; Bone Marrow; Bone Marrow Transplantation; Graft Survival; Graft vs Host Disease; Mice; Mice, Inbred AKR; Minor Lymphocyte Stimulatory Antigens; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Spleen; Survival Analysis | 1994 |
IgE-dependent activation of Fc epsilon RII/CD23+ normal human keratinocytes: the role of cAMP and nitric oxide.
Topics: Amino Acid Oxidoreductases; Arginine; Bucladesine; Cyclic AMP; Cyclic GMP; Epidermal Cells; Humans; Immunoglobulin E; Interleukin-6; Keratinocytes; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Receptors, IgE; Signal Transduction; Thionucleotides; Tumor Necrosis Factor-alpha | 1994 |
Pineal nitric oxide synthase: characteristics, adrenergic regulation and function.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cyclic AMP; Cyclic GMP; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; omega-N-Methylarginine; Pineal Gland; Rats | 1994 |
Nitric oxide is involved in control of Trypanosoma cruzi-induced parasitemia and directly kills the parasite in vitro.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Chagas Disease; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; omega-N-Methylarginine; Spleen; Trypanosoma cruzi | 1994 |
L-thiocitrulline. A stereospecific, heme-binding inhibitor of nitric-oxide synthases.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Binding Sites; Citrulline; Cytochrome c Group; Heme; Kinetics; Male; Nitric Oxide Synthase; omega-N-Methylarginine; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Thiourea | 1994 |
The morphogenic/cytotoxic and prostaglandin-stimulating activities of interleukin-1 beta in the rat ovary are nitric oxide independent.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cells, Cultured; Dinoprostone; Female; Guanidines; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; L-Lactate Dehydrogenase; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroprusside; omega-N-Methylarginine; Ovary; Rats; Rats, Sprague-Dawley; Sialoglycoproteins; Transforming Growth Factor beta | 1994 |
Production of nitric oxide by differentiated LSTRA cells is associated with expression of macrophage-inducible nitric oxide synthase.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Bucladesine; Canavanine; Cell Differentiation; Gene Expression; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Central inhibition of nitric oxide synthase attenuates water intake but does not alter enhanced glucose utilization in the hypothalamo-neurohypophysial system of dehydrated rats.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Dehydration; Deoxyglucose; Drinking; Glucose; Hypothalamo-Hypophyseal System; Injections, Intraventricular; Male; Nitric Oxide Synthase; omega-N-Methylarginine; Oxytocin; Preoptic Area; Rats; Rats, Sprague-Dawley; Subfornical Organ; Vasopressins | 1994 |
Nitric oxide-related inhibition of carotid chemosensory nerve activity in the cat.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Carotid Body; Cats; In Vitro Techniques; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Oxygen; Perfusion | 1994 |
Arginine metabolism in experimental glomerulonephritis: interaction between nitric oxide synthase and arginase.
Topics: Amino Acid Oxidoreductases; Animals; Arginase; Arginine; Cells, Cultured; Glomerular Mesangium; Glomerulonephritis; Humans; Immunoglobulin G; Kidney Glomerulus; Kinetics; Lipopolysaccharides; Macrophages; Male; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Rats; Rats, Inbred Lew; Reference Values; Urea | 1994 |
Nitric oxide-mediated apoptosis in murine mastocytoma.
Topics: Amino Acid Oxidoreductases; Animals; Apoptosis; Arginine; Cell Division; Cell Line; Cell Survival; Dexamethasone; DNA, Neoplasm; Dose-Response Relationship, Drug; Enzyme Induction; Gene Expression; Mast-Cell Sarcoma; Mice; Microscopy, Electron; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; RNA, Messenger; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1994 |
Asbestos fibers and interferon-gamma up-regulate nitric oxide production in rat alveolar macrophages.
Topics: Amino Acid Oxidoreductases; Animals; Aorta; Arginine; Asbestos, Crocidolite; Asbestos, Serpentine; Biological Assay; Cells, Cultured; Culture Media, Conditioned; Interferon-gamma; Iron Carbonyl Compounds; L-Lactate Dehydrogenase; Macrophages, Alveolar; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Organometallic Compounds; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Up-Regulation | 1994 |
The intercellular communication via nitric oxide and its regulation in coupling of cyclic GMP synthesis upon stimulation of muscarinic cholinergic receptors in rat superior cervical sympathetic ganglia.
Topics: Acetylcholine; Amino Acid Oxidoreductases; Animals; Arginine; Axons; Carbachol; Cell Communication; Cholinergic Antagonists; Cyclic GMP; Denervation; Female; Hemoglobins; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Wistar; Receptors, Cholinergic; Superior Cervical Ganglion; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Trifluoperazine | 1994 |
Nitric oxide: an autocrine regulator of human granulosa-luteal cell steroidogenesis.
Topics: Amino Acid Oxidoreductases; Arginine; Aromatase; Base Sequence; Cells, Cultured; Corpus Luteum; Cyclic GMP; Dose-Response Relationship, Drug; Estradiol; Female; Fluorescence; Granulosa Cells; Humans; Immunohistochemistry; Molecular Sequence Data; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Polymerase Chain Reaction; Progesterone; RNA, Messenger | 1994 |
The involvement of nitric oxide in the ovulatory process in the rat.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Chorionic Gonadotropin; Dose-Response Relationship, Drug; Female; Guanidines; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Ovulation; Rats; Rats, Wistar | 1994 |
p53 expression in nitric oxide-induced apoptosis.
Topics: Amino Acid Oxidoreductases; Animals; Apoptosis; Arginine; Cell Line; Genes, p53; Glutathione; Interferon-gamma; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitroso Compounds; omega-N-Methylarginine; Rats; S-Nitrosoglutathione; Tumor Suppressor Protein p53; Up-Regulation | 1994 |
Cardiovascular effects of NG-methyl-L-arginine in chronically instrumented conscious dogs.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Gas Analysis; Blood Pressure; Body Temperature; Cardiac Output; Dogs; Female; Hematocrit; Hemodynamics; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Regional Blood Flow | 1994 |
TNF-alpha and IFN-gamma stimulate a macrophage precursor cell line to kill Listeria monocytogenes in a nitric oxide-independent manner.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Line; Female; Guanidines; Interferon-gamma; Listeria monocytogenes; Macrophages; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Tumor Necrosis Factor-alpha | 1994 |
Chronic changes in blood flow alter endothelium-dependent responses in autogenous vein grafts in dogs.
Topics: Acetylcholine; Adenosine Diphosphate; Adrenergic alpha-Agonists; Animals; Arginine; Arteriovenous Shunt, Surgical; Blood Flow Velocity; Brimonidine Tartrate; Calcimycin; Constriction; Dinoprost; Dogs; Endothelins; Endothelium, Vascular; Femoral Artery; Femoral Vein; Hyperplasia; Male; Models, Biological; Neovascularization, Pathologic; Nitric Oxide; omega-N-Methylarginine; Quinoxalines; Thrombin; Tunica Intima; Vascular Patency | 1994 |
Effects of N omega-monomethyl-L-arginine on short-term RR interval and systolic blood pressure oscillations.
Topics: Animals; Arginine; Blood Pressure; Electrocardiography; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System | 1994 |
Presence of constitutive type nitric oxide synthase in cultured astrocytes isolated from rat cerebra.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Astrocytes; Brain; Cells, Cultured; Citrulline; Cyclic GMP; Histocytochemistry; NADPH Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats | 1994 |
Polyamines inhibit nitric oxide synthase in rat cerebellum.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cells, Cultured; Cerebellum; Citrulline; Cytosol; Eflornithine; Kinetics; N-Methylaspartate; Neurons; Nitric Oxide Synthase; omega-N-Methylarginine; Polyamines; Putrescine; Rats; Spermidine; Spermine; Tritium | 1994 |
IL-1 inhibits beta-adrenergic control of cardiac calcium current: role of L-arginine/nitric oxide pathway.
Topics: Adrenergic beta-Antagonists; Amino Acid Oxidoreductases; Animals; Arginine; Calcium Channels; Cells, Cultured; Colforsin; Guinea Pigs; Heart; Heart Ventricles; Humans; Interleukin-1; Isoproterenol; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Receptors, Adrenergic, beta; Recombinant Proteins | 1994 |
Induction of hepatic Ito cell nitric oxide production after acute endotoxemia.
Topics: Acute Disease; Amino Acid Oxidoreductases; Analysis of Variance; Animals; Arginine; Cells, Cultured; DNA; Endotoxins; Granulocyte-Macrophage Colony-Stimulating Factor; Interferon-gamma; Lipopolysaccharides; Liver; Macrophage Colony-Stimulating Factor; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Toxemia; Tumor Necrosis Factor-alpha | 1994 |
The effects of nitric oxide inhibition on regional hemodynamics during hyperdynamic endotoxemia.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Bacteremia; Blood Gas Analysis; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Escherichia coli Infections; Hemodynamics; NADPH Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Sepsis | 1994 |
Characterization of the inactivation of nitric oxide synthase by NG-methyl-L-arginine: evidence for heme loss.
Topics: Amino Acid Oxidoreductases; Arginine; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Citrulline; Cytochrome P-450 Enzyme System; Enzyme Stability; Heme; Hemeproteins; Hydrogen Peroxide; Isotope Labeling; Nitric Oxide Synthase; omega-N-Methylarginine; Solubility; Spectrophotometry; Tritium | 1994 |
Nitric oxide production is intensely and persistently increased in tissue by thermal injury.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Brain; Burns; Female; Liver; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Stomach | 1994 |
Electron transfer in the nitric-oxide synthases. Characterization of L-arginine analogs that block heme iron reduction.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Biological Transport; Cells, Cultured; Citrulline; Cloning, Molecular; Electrons; Heme; Humans; Iron; Kinetics; NADP; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Oxidation-Reduction; Rats; Thiourea | 1994 |
Effect of inhibition of nitric oxide synthase in acute renal failure due to endotoxin shock in dogs.
Topics: Acute Kidney Injury; Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Disease Models, Animal; Dogs; Hemodynamics; Kidney; Lipopolysaccharides; Liver; Nitric Oxide Synthase; omega-N-Methylarginine; Shock, Septic | 1994 |
Toxic acute renal failure in the rat: effects of L-arginine and N-methyl-L-arginine on renal function.
Topics: Acute Kidney Injury; Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Creatinine; Female; Glomerular Filtration Rate; Natriuresis; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Uranyl Nitrate | 1994 |
Chronotropic effects of cytokines and the nitric oxide synthase inhibitor, L-NMMA, on cardiac myocytes.
Topics: Amino Acid Oxidoreductases; Analysis of Variance; Animals; Animals, Newborn; Arginine; Cells, Cultured; Cytokines; Dose-Response Relationship, Drug; Heart; Heart Rate; Interleukin-1; Interleukin-6; Kinetics; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Tumor Necrosis Factor-alpha | 1994 |
Protective role of NO in hepatic microcirculatory dysfunction during endotoxemia.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Lipopolysaccharides; Liver Circulation; Male; Mice; Mice, Inbred C57BL; Microcirculation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine | 1994 |
Regulation of inducible nitric oxide synthase gene by interleukin-1 beta in rat vascular endothelial cells.
Topics: Amino Acid Oxidoreductases; Animals; Aorta; Arginine; Blotting, Northern; Cells, Cultured; DNA Probes; Endothelium, Vascular; Gene Expression Regulation; Interferon-gamma; Interleukin-1; Lipopolysaccharides; Mice; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; RNA, Messenger; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 1994 |
Acute compensation to abrupt occlusion of rat femoral artery is prevented by NO synthase inhibitors.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Flow Velocity; Blood Pressure; Constriction; Femoral Artery; Iliac Artery; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley | 1994 |
Nitric oxide modulates prostacyclin biosynthesis in the lung of endotoxin-treated rats.
Topics: 6-Ketoprostaglandin F1 alpha; Amino Acid Oxidoreductases; Animals; Arginine; Dose-Response Relationship, Drug; Enzyme Induction; Epoprostenol; In Vitro Techniques; Injections, Subcutaneous; Lipopolysaccharides; Lung; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar | 1994 |
Role of nitric oxide in parasympathetic modulation of beta-adrenergic myocardial contractility in normal dogs.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cyclic AMP; Dobutamine; Dogs; Electric Stimulation; Heart; Heart Rate; Muscarinic Antagonists; Myocardial Contraction; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Receptors, Adrenergic, beta; Vagus Nerve | 1995 |
Lipopolysaccharide-induced hypotension and vascular hyporeactivity in the rat: tissue analysis of nitric oxide synthase mRNA and protein expression in the presence and absence of dexamethasone, NG-monomethyl-L-arginine or indomethacin.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Dexamethasone; Female; Gene Expression; Indomethacin; Lipopolysaccharides; Nitric Oxide Synthase; Norepinephrine; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; RNA, Messenger; Shock, Septic; Tissue Distribution; Vasodilation | 1995 |
Gamma interferon-induced, nitric oxide-mediated inhibition of vaccinia virus replication.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Line; DNA, Viral; Gene Expression; Interferon-gamma; Mice; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Vaccinia virus; Viral Proteins; Virus Replication | 1995 |
Role of nitric oxide in control of prolactin release by the adenohypophysis.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Atrial Natriuretic Factor; Cyclic GMP; Dibutyryl Cyclic GMP; Dopamine; Dose-Response Relationship, Drug; Guanylate Cyclase; Hemoglobins; In Vitro Techniques; Luteinizing Hormone; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Wistar; Substance P; Vasoactive Intestinal Peptide | 1995 |
[Change in the tone of coronary vessels as a result of immobilization stress].
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Coronary Vessels; Female; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Stress, Physiological; Vasodilation | 1994 |
Gastric mucosal nitric oxide synthase activity: inhibition by phosphorylation, arginine analogues and trifluoperazine.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Canavanine; Gastric Mucosa; In Vitro Techniques; Kinetics; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Phosphorylation; Rats; Trifluoperazine | 1994 |
Effects of nitric oxide synthase inhibitors on murine infection with Mycobacterium tuberculosis.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Guanidines; Mice; Mice, Inbred C57BL; Mycobacterium tuberculosis; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Tuberculosis | 1995 |
Immediate arousal response and adaptation to low-dose x-rays in mouse and its disappearance by olfactory bulbectomy and nitric oxide inhibitor.
Topics: Adaptation, Physiological; Amino Acid Oxidoreductases; Animals; Arginine; Arousal; Electroencephalography; Male; Mice; Mice, Inbred ICR; Nerve Tissue Proteins; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Olfactory Bulb; omega-N-Methylarginine; Sleep | 1994 |
Functional expression of three isoforms of human nitric oxide synthase in baculovirus-infected insect cells.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Baculoviridae; Blotting, Western; Cell Line; Chromatography, Affinity; DNA, Complementary; Endothelium, Vascular; Enzyme Induction; Gene Expression; Guanidines; Humans; Isoenzymes; Kinetics; Mice; Neurons; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Ornithine; Recombinant Proteins; Spodoptera; Transfection | 1995 |
[Changes in the endotheliocyte activity of the coronary vessels under the influence of stress].
Topics: Animals; Arginine; Coronary Circulation; Coronary Vessels; Endothelium, Vascular; Female; Homeostasis; In Vitro Techniques; Myocardial Contraction; Nitric Oxide; omega-N-Methylarginine; Rats; Restraint, Physical; Saponins; Statistics, Nonparametric; Stress, Physiological; Vasodilation | 1994 |
Lymphocyte-mediated nitric oxide production by rat endothelial cells.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blotting, Western; Cell Communication; Cell Movement; Cells, Cultured; Concanavalin A; Endothelium, Vascular; Female; Lipopolysaccharides; Lymphocytes; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phytohemagglutinins; Rats; Rats, Sprague-Dawley; Specific Pathogen-Free Organisms; Spleen; Thymus Gland; Wheat Germ Agglutinins | 1995 |
Muscarinic cholinergic stimulation of the nitric oxide-cyclic GMP signaling system in cultured rat sensory neurons.
Topics: Acetylcholine; Amino Acid Oxidoreductases; Animals; Arginine; Atropine; Capsaicin; Carbachol; Cells, Cultured; Cyclic GMP; Embryo, Mammalian; Ganglia, Spinal; Guanylate Cyclase; Methacholine Chloride; Methylene Blue; Neurons, Afferent; Nicotine; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Oxotremorine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Signal Transduction | 1994 |
Nitric oxide synthase inhibition and platelet function.
Topics: Adult; Amino Acid Oxidoreductases; Arginine; beta-Thromboglobulin; Blood Platelets; Humans; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Activation; Platelet Aggregation; Platelet Count; Platelet Factor 4 | 1994 |
Dilatation of cerebral arterioles in response to lipopolysaccharide in vivo.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Arterioles; Cerebral Arteries; Dexamethasone; Female; Indomethacin; Lipopolysaccharides; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rabbits; Vasodilation | 1995 |
First place winner of the Conrad Jobst Award in the gold medal paper competition. Nitric oxide synthase inhibitors N-monomethylarginine and aminoguanidine prevent the progressive and severe hypotension associated with a rat model of pancreatitis.
Topics: Amylases; Animals; Arginine; Blood Pressure; Calcium; Clinical Protocols; Disease Models, Animal; Drug Evaluation, Preclinical; Fluid Therapy; Guanidines; Humans; Hypotension; Immunohistochemistry; Male; Multiple Organ Failure; Nitric Oxide; omega-N-Methylarginine; Pancreatitis; Premedication; Rats; Rats, Sprague-Dawley; Resuscitation; Severity of Illness Index | 1995 |
Reduction by NG-nitro-L-arginine of H2O2-induced endothelial cell injury.
Topics: Amino Acid Oxidoreductases; Animals; Aorta, Thoracic; Arginine; Cattle; Cell Survival; Cells, Cultured; Chromium Radioisotopes; Citrulline; Endothelium, Vascular; Hydrogen Peroxide; L-Lactate Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine | 1994 |
Targeted disruption of the NF-IL6 gene discloses its essential role in bacteria killing and tumor cytotoxicity by macrophages.
Topics: Animals; Arginine; Base Sequence; Biological Assay; CCAAT-Enhancer-Binding Proteins; Cytotoxicity, Immunologic; DNA Primers; DNA-Binding Proteins; Granulocyte Colony-Stimulating Factor; Hydrogen Peroxide; Interferon-gamma; Interleukin-6; Listeria monocytogenes; Listeriosis; Macrophage Activation; Macrophages, Peritoneal; Mice; Mice, Mutant Strains; Mice, Transgenic; Molecular Sequence Data; Nitric Oxide; Nuclear Proteins; omega-N-Methylarginine; Polymerase Chain Reaction; Stem Cells; Superoxides; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1995 |
Contribution of nitric oxide to coronary vasodilation during hypercapnic acidosis.
Topics: Acetylcholine; Acidosis; Adenosine; Amino Acid Oxidoreductases; Animals; Arginine; Carbon Dioxide; Coronary Circulation; Coronary Vessels; Dogs; Endothelium, Vascular; Extracorporeal Circulation; Female; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Oxygen; Partial Pressure; Vasodilation | 1995 |
Effect of lipopolysaccharide on nitric oxide synthase activity in rat proximal tubules.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Citrulline; Kidney Tubules, Proximal; Kinetics; Lipopolysaccharides; Male; NADP; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley | 1995 |
Nitric oxide synthase inhibitors do not alter functional hyperemia in canine skeletal muscle.
Topics: Acetylcholine; Amino Acid Oxidoreductases; Animals; Arginine; Blood Flow Velocity; Bradykinin; Dogs; Endothelium; Female; Femoral Artery; Hyperemia; Male; Muscles; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Oxygen Consumption; Vasoconstriction | 1994 |
Forearm blood flow responses to a nitric oxide synthase inhibitor in patients with treated essential hypertension.
Topics: Adult; Aged; Amino Acid Oxidoreductases; Arginine; Female; Forearm; Humans; Hypertension; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; omega-N-Methylarginine; Plethysmography; Regional Blood Flow; Vasodilation | 1994 |
Nitric oxide synthase inhibitors prevent N-methyl-D-aspartic acid-induced penile erection and yawning in male rats.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Dose-Response Relationship, Drug; Free Radical Scavengers; Injections; Male; Methemoglobin; Methylene Blue; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Paraventricular Hypothalamic Nucleus; Penile Erection; Rats; Rats, Sprague-Dawley; Yawning | 1994 |
Nitric oxide synthase inhibitor alters papillary muscle force-frequency relationship.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Calcium Channels; Cricetinae; Cyclic GMP; Electric Stimulation; In Vitro Techniques; Male; Mesocricetus; Myocardial Contraction; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Papillary Muscles | 1995 |
Role of L-arginine-derived NO in ischemic acute renal failure in the rat.
Topics: Acute Kidney Injury; Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Disease Models, Animal; Female; Glomerular Filtration Rate; Ischemia; Kidney; Natriuresis; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Urodynamics | 1994 |
The mechanism of the inhibitory effect of polyamines on the induction of nitric oxide synthase: role of aldehyde metabolites.
Topics: Aldehydes; Amino Acid Oxidoreductases; Animals; Arginine; Blood Physiological Phenomena; Cattle; Cell Line; Dinoprost; Enzyme Induction; Lipopolysaccharides; Mice; Nitric Oxide Synthase; omega-N-Methylarginine; Oxidation-Reduction; Spermine; Tumor Necrosis Factor-alpha | 1994 |
Nitric oxide mediates cytotoxicity and basic fibroblast growth factor release in cultured vascular smooth muscle cells. A possible mechanism of neovascularization in atherosclerotic plaques.
Topics: Animals; Aorta; Aorta, Thoracic; Arginine; Arteriosclerosis; Cattle; Cell Division; Cells, Cultured; DNA; Endothelium, Vascular; Fibroblast Growth Factor 2; Immunohistochemistry; Interleukin-1; Kinetics; L-Lactate Dehydrogenase; Muscle, Smooth, Vascular; Neovascularization, Pathologic; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Rats; Rats, Wistar | 1995 |
The lethal effects of cytokine-induced nitric oxide on cardiac myocytes are blocked by nitric oxide synthase antagonism or transforming growth factor beta.
Topics: Amino Acid Oxidoreductases; Analysis of Variance; Animals; Arginine; Cell Communication; Cell Line; Cells, Cultured; Cytokines; Heart; Interferon-gamma; Lipopolysaccharides; Macrophages; Male; Mice; Myocardium; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Wistar; Transcription, Genetic; Transforming Growth Factor beta | 1995 |
Tyrosine kinase inhibitors enhance cGMP production in rat pinealocytes.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Oxidoreductases; Animals; Arginine; Catechols; Cyclic AMP; Cyclic GMP; Genistein; Hydroquinones; Isoflavones; Isoproterenol; Male; Nitric Oxide Synthase; Nitriles; Norepinephrine; omega-N-Methylarginine; Pineal Gland; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Tyrphostins | 1995 |
Inhibition of nitric oxide synthase alters light responses and dark voltage of amphibian photoreceptors.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Calcium; Darkness; Electrophysiology; In Vitro Techniques; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Patch-Clamp Techniques; Photic Stimulation; Photoreceptor Cells; Rana temporaria; Retinal Rod Photoreceptor Cells | 1994 |
Nitric oxide synthase inhibition reduces wakefulness.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Arousal; Electroencephalography; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Wistar; Sleep; Sleep, REM; Wakefulness | 1994 |
Attenuation of some signs of opioid withdrawal by inhibitors of nitric oxide synthase.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Behavior, Animal; Dose-Response Relationship, Drug; Male; Morphine Dependence; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Inbred F344; Substance Withdrawal Syndrome; Weight Loss | 1993 |
Antiepileptic effects of inhibitors of nitric oxide synthase examined in pentylenetetrazol-induced seizures in rats.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Calmodulin-Binding Proteins; Epilepsy; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Pentylenetetrazole; Rats; Rats, Wistar | 1994 |
Expression of intrahepatic inducible nitric oxide synthetase mRNA correlates with production of nitric oxide during intraportal isogeneic and allogeneic rat islet transplantation.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Diabetes Mellitus, Experimental; Enzyme Induction; Gene Expression; Graft Rejection; Islets of Langerhans Transplantation; Liver; Nitrates; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Polymerase Chain Reaction; Portal System; Rats; Rats, Inbred Lew; Rats, Wistar; RNA, Messenger; T-Lymphocytes; Time Factors; Transplantation, Homologous; Transplantation, Isogeneic | 1995 |
Effects of nitric oxide synthase inhibition combined with nitric oxide inhalation in a porcine model of endotoxin shock.
Topics: Administration, Inhalation; Amino Acid Oxidoreductases; Animals; Arginine; Blood Gas Analysis; Escherichia coli; Hemodynamics; Hydrogen-Ion Concentration; Leukocyte Count; Lipopolysaccharides; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Platelet Count; Shock, Septic; Swine; Tumor Necrosis Factor-alpha | 1995 |
Pharmacological evidence that nitric oxide may be a retrograde messenger in the enteric nervous system.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Enteric Nervous System; Guinea Pigs; In Vitro Techniques; Interneurons; Intestine, Small; Motor Neurons; Neuromuscular Junction; Neurons, Afferent; Neurotransmitter Agents; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Physical Stimulation; Synapses; Synaptic Transmission | 1995 |
Nitric oxide synthesis and the effect of aminoguanidine and NG-monomethyl-L-arginine on the onset of diabetes in the spontaneously diabetic BB rat.
Topics: Aging; Amino Acid Oxidoreductases; Animals; Arginine; Diabetes Mellitus, Type 1; Guanidines; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Inbred BB; Species Specificity; Time Factors | 1995 |
Inducible nitric oxide synthase in rat hepatic lipocytes and the effect of nitric oxide on lipocyte contractility.
Topics: Adipocytes; Amino Acid Oxidoreductases; Animals; Arginine; Base Sequence; Cell Movement; Cells, Cultured; Common Bile Duct; Cyclic GMP; Cytokines; Enzyme Induction; Liver; Male; Molecular Sequence Data; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1995 |
Role of nitric oxide in regulation of baroreceptor reflex.
Topics: Afferent Pathways; Amino Acid Oxidoreductases; Animals; Aorta; Arginine; Baroreflex; Blood Pressure; Female; Heart Rate; Kidney; Nitric Oxide; Nitric Oxide Synthase; Nitroglycerin; omega-N-Methylarginine; Rabbits; Receptors, Presynaptic; Sympathetic Nervous System | 1994 |
Nitric oxide formation is involved in vagal inhibition of the stomach of the trout (Salmo gairdneri).
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Atropine; Electric Stimulation; Female; Gastric Mucosa; Male; Muscle Contraction; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase; Nitroglycerin; Nitroprusside; omega-N-Methylarginine; Oncorhynchus mykiss; Stomach; Vagus Nerve | 1994 |
Inhibitors of free radical formation fail to attenuate direct beta-amyloid25-35 peptide-mediated neurotoxicity in rat hippocampal cultures.
Topics: Allopurinol; Alzheimer Disease; Amino Acid Oxidoreductases; Amyloid beta-Peptides; Animals; Arginine; Catalase; Cell Death; Cells, Cultured; Embryo, Mammalian; Free Radical Scavengers; Free Radicals; Hippocampus; Humans; Indomethacin; Masoprocol; Neurons; Neurotoxins; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Oxypurinol; Peptide Fragments; Quinacrine; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Xanthine Oxidase | 1994 |
Stimulation of IRE-BP activity of IRF by tetrahydrobiopterin and cytokine dependent induction of nitric oxide synthase.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Biopterins; Cell Line; Chloramphenicol O-Acetyltransferase; Deferoxamine; Humans; Interferon-gamma; Iron; Iron-Regulatory Proteins; Kinetics; Leukemia, Myeloid, Acute; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; RNA Probes; RNA-Binding Proteins; Transfection; Tumor Cells, Cultured | 1994 |
Reciprocal modulation of aconitase activity and RNA-binding activity of iron regulatory factor by nitric oxide.
Topics: Aconitate Hydratase; Adenocarcinoma; Amino Acid Oxidoreductases; Animals; Arginine; Cell Line; Interferon-gamma; Iron-Regulatory Proteins; Leukemia P388; Lipopolysaccharides; Macrophages; Mice; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Recombinant Proteins; RNA-Binding Proteins; RNA, Messenger; Tumor Cells, Cultured; Vasodilator Agents | 1994 |
Characterization of neuronal amino acid transporters: uptake of nitric oxide synthase inhibitors and implication for their biological effects.
Topics: Amino Acid Oxidoreductases; Amino Acid Transport Systems; Amino Acids; Animals; Arginine; Biological Transport; Carrier Proteins; Cyclic GMP; Mice; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Tumor Cells, Cultured | 1995 |
Lipopolysaccharide-induced changes in plasma nitrite and nitrate concentrations in rats and mice: pharmacological evaluation of nitric oxide synthase inhibitors.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Dexamethasone; Dose-Response Relationship, Drug; Guanidines; Lipopolysaccharides; Male; Mice; Mice, Inbred Strains; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Time Factors | 1995 |
Nitric oxide synthase inhibitor and lipopolysaccharide effects on reactivity of guinea pig airways.
Topics: Airway Resistance; Amino Acid Oxidoreductases; Animals; Arginine; Epithelium; Guanidines; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Lipopolysaccharides; Male; Methacholine Chloride; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Penicillamine; Respiration; S-Nitroso-N-Acetylpenicillamine; Trachea | 1995 |
Nitric oxide synthesis in rat mesangial cells induced by cytokines.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Oxidoreductases; Animals; Arginine; Cells, Cultured; Chemotactic Factors; Cyclic GMP; Cycloheximide; Cytokines; Dactinomycin; Dexamethasone; Dose-Response Relationship, Drug; Gene Expression; Glomerular Mesangium; Interleukin-1; Interleukin-6; Interleukin-8; Kinetics; Male; Monocyte Chemoattractant Proteins; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Transcription, Genetic; Transforming Growth Factor beta | 1994 |
Effects of NMDA receptor blockade and nitric oxide synthase inhibition on the acute and chronic actions of delta 9-tetrahydrocannabinol in mice.
Topics: Amino Acid Oxidoreductases; Analgesia; Animals; Arginine; Dizocilpine Maleate; Dronabinol; Drug Tolerance; Hypothermia, Induced; Male; Mice; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Receptors, N-Methyl-D-Aspartate | 1994 |
Co-localization of inducible-nitric oxide synthase and Plasmodium berghei in hepatocytes from rats immunized with irradiated sporozoites.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Female; Fluorescent Antibody Technique; Guanidines; Liver; Malaria Vaccines; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Plasmodium berghei; Primaquine; Rats; Rats, Inbred BN; Vaccines, Attenuated | 1995 |
Endotoxin-induced nonendothelial nitric oxide activates the Ca(2+)-activated K+ channel in cultured vascular smooth muscle cells.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Calcium; Cells, Cultured; Cyclic N-Oxides; Endotoxins; Enzyme Induction; Imidazoles; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Patch-Clamp Techniques; Potassium Channels; Swine | 1994 |
Amino acids differentially inhibit the L-[3H]arginine transport and nitric oxide synthase in rat brain synaptosomes.
Topics: Amino Acid Oxidoreductases; Amino Acids; Animals; Arginine; Biological Transport; Brain; Chick Embryo; Cytosol; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Wistar; Synaptosomes; Tritium | 1994 |
Effect of opioid receptor agonists on nitric oxide synthase activity in rat cerebral cortex homogenate.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cerebral Cortex; Citrulline; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Receptors, Opioid | 1994 |
Pulmonary alveolar epithelial inducible NO synthase gene expression: regulation by inflammatory mediators.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood; Cells, Cultured; Cytokines; Epithelium; Female; Fluorescent Antibody Technique; Gene Expression Regulation, Enzymologic; Lipopolysaccharides; Nitrates; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Pregnancy; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Zymosan | 1995 |
In vivo treatment with endotoxin induces nitric oxide synthase in rat main pulmonary artery.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Base Sequence; Cyclic GMP; Dexamethasone; Endothelium, Vascular; Guanidines; Lipopolysaccharides; Male; Molecular Sequence Data; Muscle Contraction; Nitric Oxide Synthase; omega-N-Methylarginine; Phenylephrine; Phosphatidylethanolamines; Potassium Chloride; Pulmonary Artery; Rats; Rats, Wistar; RNA, Messenger | 1995 |
Critical role of endothelium in sustained arterial contraction during prolonged hypoxia.
Topics: Adenosine Triphosphate; Amino Acid Oxidoreductases; Animals; Aorta, Thoracic; Arginine; Endothelium, Vascular; Glyburide; Hypoxia; In Vitro Techniques; Indomethacin; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Oxyhemoglobins; Potassium Channel Blockers; Potassium Channels; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasodilation | 1995 |
Role of nitric oxide in the relationship of pancreatic blood flow and exocrine secretion in cats.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cats; Cholecystokinin; Female; Male; Microcirculation; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Pancreas; Regional Blood Flow; Secretin | 1995 |
Transfection with the inducible nitric oxide synthase gene suppresses tumorigenicity and abrogates metastasis by K-1735 murine melanoma cells.
Topics: Amino Acid Oxidoreductases; Animals; Apoptosis; Arginine; Enzyme Induction; Female; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Nude; Neoplasm Metastasis; Neoplasm Transplantation; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Recombinant Fusion Proteins; Specific Pathogen-Free Organisms; Transfection; Tumor Cells, Cultured | 1995 |
Amplification of nitric oxide synthase expression by nitric oxide in interleukin 1 beta-stimulated rat mesangial cells.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blotting, Northern; Cell Nucleus; Citrulline; Gene Expression Regulation, Enzymologic; Glomerular Mesangium; Interleukin-1; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroprusside; omega-N-Methylarginine; Penicillamine; Rats; RNA, Messenger; S-Nitroso-N-Acetylpenicillamine; Time Factors; Transcription, Genetic | 1995 |
Bidirectional regulation of osteoclast function by nitric oxide synthase isoforms.
Topics: Adult; Amino Acid Oxidoreductases; Animals; Animals, Newborn; Arginine; Base Sequence; Calcium; Cell Differentiation; Cell Division; Cell Line; Cells, Cultured; Clone Cells; Dihydrolipoamide Dehydrogenase; DNA Primers; Female; Filaggrin Proteins; Gene Expression; Humans; Immunohistochemistry; Interferon-gamma; Isoenzymes; Lipopolysaccharides; Molecular Sequence Data; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Osteoclasts; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tetradecanoylphorbol Acetate | 1995 |
Aminoguanidine inhibits both constitutive and inducible nitric oxide synthase isoforms in rat intestinal microvasculature in vivo.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Capillary Permeability; Guanidines; Intestines; Male; Microcirculation; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Wistar | 1995 |
Evidence that acetylcholine mediates increased cerebral blood flow velocity in crucian carp through a nitric oxide-dependent mechanism.
Topics: Acetylcholine; Amino Acid Oxidoreductases; Animals; Arginine; Blood Flow Velocity; Carps; Cerebrovascular Circulation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine | 1995 |
Natriuretic peptide-augmented induction of nitric oxide synthase through cyclic guanosine 3',5'-monophosphate elevation in vascular smooth muscle cells.
Topics: Amino Acid Oxidoreductases; Animals; Antihypertensive Agents; Aorta; Arginine; Atrial Natriuretic Factor; Cells, Cultured; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Induction; Humans; Interleukin-1; Kinetics; Muscle, Smooth, Vascular; Natriuretic Peptide, C-Type; Nerve Tissue Proteins; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Proteins; Rats; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1995 |
Novel potent and selective inhibitors of inducible nitric oxide synthase.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Enzyme Induction; Isoenzymes; Isothiuronium; Mice; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Thiazines | 1995 |
Rapid induction of mRNA for nitric oxide synthase II in rat alveolar macrophages by intratracheal administration of Mycobacterium tuberculosis and Mycobacterium avium.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Base Sequence; Bronchoalveolar Lavage Fluid; Humans; Lung; Macrophages, Alveolar; Male; Molecular Sequence Data; Mycobacterium avium Complex; Mycobacterium tuberculosis; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tumor Necrosis Factor-alpha | 1995 |
Administration of nitric oxide synthase inhibitors in experimental autoimmune neuritis and experimental autoimmune encephalomyelitis.
Topics: Acetates; Amino Acid Oxidoreductases; Animals; Arginine; Encephalomyelitis, Autoimmune, Experimental; Female; Guanidines; Mice; Mice, Inbred Strains; Myelin Basic Protein; Neuritis, Autoimmune, Experimental; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Inbred Lew | 1995 |
Nitric oxide and the cyclooxygenase pathway.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Bradykinin; Dinoprostone; Enzyme Induction; Escherichia coli; Guanidines; Hydronephrosis; Indomethacin; Inflammation; Lipopolysaccharides; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Prostaglandin-Endoperoxide Synthases; Rabbits; Rats | 1995 |
Cyclic nucleotides and vasoactive intestinal peptide production in a rabbit model of Escherichia coli septicemia.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Bacteremia; Blood Pressure; Cyclic AMP; Cyclic GMP; Disease Models, Animal; Escherichia coli Infections; Heart Rate; Lactates; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rabbits; Reference Values; Vasoactive Intestinal Peptide | 1995 |
Colchicine induces apoptosis in cerebellar granule cells.
Topics: Amino Acid Oxidoreductases; Animals; Apoptosis; Arginine; Calcium; Cell Survival; Cells, Cultured; Cerebellum; Colchicine; Cyclosporine; Dizocilpine Maleate; DNA; Kinetics; Neurons; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Paclitaxel; Rats; Rats, Sprague-Dawley; tau Proteins; Time Factors; Tubulin | 1995 |
IL-1-induced nitric oxide inhibits chondrocyte proliferation via PGE2.
Topics: Amino Acid Oxidoreductases; Arginine; Cartilage; Cell Division; Cells, Cultured; Culture Media; Dinoprostone; Humans; Indomethacin; Interleukin-1; Kinetics; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Thymidine; Transforming Growth Factor beta | 1995 |
Role of nitric oxide in ischemia/reperfusion of the rat kidney.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Kidney; Lipid Peroxidation; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Survival Rate | 1994 |
Augmentation of cancer chemotherapy by preinjection of human macrophage colony-stimulating factor in L1210 leukemic cell-inoculated mice.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Doxorubicin; Kinetics; Leukemia L1210; Liver; Macrophage Colony-Stimulating Factor; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Nitric Oxide Synthase; omega-N-Methylarginine; Spleen; Survival Rate | 1995 |
Dysmorphogenic effects of nitric oxide (NO) and NO-synthase inhibition: studies with intra-amniotic injections of sodium nitroprusside and NG-monomethyl-L-arginine.
Topics: Amino Acid Oxidoreductases; Amnion; Animals; Arginine; Culture Techniques; Embryonic and Fetal Development; Hemoglobins; Light; Microinjections; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Protein Binding; Rats; Rats, Sprague-Dawley | 1994 |
Effect of pentoxifylline on nitric oxide released by murine macrophages.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cells, Cultured; Endotoxins; Interferon-gamma; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Mice, Inbred CBA; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Pentoxifylline; Staphylococcus epidermidis; Tumor Necrosis Factor-alpha | 1995 |
Role of cyclic nucleotides and nitric oxide in blood mononuclear cell IgE production stimulated by IL-4.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Arginine; B-Lymphocytes; Cholera Toxin; Cyclic AMP; Cyclic GMP; Drug Synergism; Epinephrine; Gene Expression Regulation; Humans; Immunoglobulin E; Interleukin-4; Leukocytes, Mononuclear; Molsidomine; Nitric Oxide; omega-N-Methylarginine; Receptors, IgE; Recombinant Fusion Proteins | 1995 |
Cerebral blood flow during inhibition of brain nitric oxide synthase activity in normal, hypertensive, and stroke-prone rats.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Brain; Cerebrovascular Circulation; Female; Male; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reference Values; Regional Blood Flow; Species Specificity; Structure-Activity Relationship; Vascular Resistance | 1995 |
Particulate and soluble forms of the inducible nitric oxide synthase are distinguishable at the amino terminus in RAW 264.7 macrophage cells.
Topics: Amino Acid Oxidoreductases; Amino Acid Sequence; Animals; Arginine; Blotting, Western; Cell Line; Cell Membrane; Cytosol; Drug Synergism; Enzyme Induction; Escherichia coli; Interferon-gamma; Isoenzymes; Lipopolysaccharides; Macrophages; Mice; Molecular Sequence Data; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Ornithine; Sequence Deletion | 1995 |
Further characterization and comparison of inducible nitric oxide synthase in mouse, rat, and human hepatocytes.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Oxidoreductases; Animals; Arginine; Cells, Cultured; Cyclic GMP; Dexamethasone; Enzyme Induction; Gene Expression; Humans; Interferon-gamma; Interleukin-1; Interleukins; Isoenzymes; Lipopolysaccharides; Liver; Mice; Nitrates; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Rats; Recombinant Proteins; RNA, Messenger; Species Specificity; Tumor Necrosis Factor-alpha | 1995 |
Capillary hydraulic conductivity is decreased by nitric oxide synthase inhibition.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Capillary Permeability; Male; Nitric Oxide Synthase; omega-N-Methylarginine; Perfusion; Rana pipiens; Splanchnic Circulation | 1995 |
Platelet-activating factor: the effector of protein-rich plasma extravasation and nitric oxide synthase induction in rat immune complex peritonitis.
Topics: Amino Acid Oxidoreductases; Analysis of Variance; Animals; Antibody Formation; Arginine; Arthus Reaction; Blotting, Northern; Cells, Cultured; Enzyme Induction; Extravasation of Diagnostic and Therapeutic Materials; Leucine; Male; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Peritoneal Cavity; Peritonitis; Phagocytes; Piperazines; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Specific Pathogen-Free Organisms | 1995 |
Reversal of refractory hypotension in septic shock by inhibitor of nitric oxide synthase.
Topics: Amino Acid Oxidoreductases; Arginine; Cardiac Output, High; Fatal Outcome; Humans; Hypotension; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Shock, Septic | 1994 |
Nitric oxide synthase inhibition irreversibly decreases perfusion in the R3230Ac rat mammary adenocarcinoma.
Topics: Adenocarcinoma; Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Female; Mammary Neoplasms, Experimental; Microcirculation; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Perfusion; Rats; Rats, Inbred F344; Regional Blood Flow; Venules | 1995 |
Nitric oxide synthase activity in molluscan hemocytes.
Topics: Amino Acid Oxidoreductases; Animals; Antibodies; Arginine; Citrulline; Hemocytes; Kinetics; Nitrates; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Rabbits; Snails | 1995 |
Met-enkephalin receptor-mediated increase of membrane fluidity modulates nitric oxide (NO) and cGMP production in rat brain synaptosomes.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cerebral Cortex; Cyclic GMP; Enkephalin, Methionine; Fluorescence Polarization; Kinetics; Membrane Fluidity; Naloxone; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Receptors, Opioid; Synaptosomes; Thermodynamics | 1995 |
Expression and functional role of nitric oxide synthase in osteoblast-like cells.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Base Sequence; Bone Neoplasms; Calcitriol; Calcium; Cell Division; Cytokines; DNA Primers; Dose-Response Relationship, Drug; Humans; Interleukin-6; Lipopolysaccharides; Molecular Sequence Data; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Osteoblasts; Osteosarcoma; Polymerase Chain Reaction; Rats; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured | 1995 |
Interleukin-1 beta suppresses apoptosis in rat ovarian follicles by increasing nitric oxide production.
Topics: Amino Acid Oxidoreductases; Animals; Apoptosis; Arginine; Chorionic Gonadotropin; Culture Techniques; Cyclic AMP; Cyclic GMP; DNA; Female; Gonadotropins, Equine; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Ovarian Follicle; Rats; Rats, Sprague-Dawley; Sialoglycoproteins | 1995 |
The nitric oxide synthase inhibitor, L-NG-monomethylarginine, reduces carrageenan-induced pleurisy in the rat.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Carrageenan; Male; Nitric Oxide Synthase; omega-N-Methylarginine; Pleurisy; Rats; Rats, Sprague-Dawley | 1995 |
Blockade of nitric oxide synthase differentially influences background activity and electrical excitability in rat dorsal horn neurones.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Electrophysiology; Neurons; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Spinal Cord | 1995 |
N-nitro-L-arginine and N-monomethyl-L-arginine exhibit a different pattern of inactivation toward the three nitric oxide synthases.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Binding Sites; Biopterins; Brain; In Vitro Techniques; Isoenzymes; Kinetics; Male; Models, Biological; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley | 1995 |
Mechanisms controlling nitric oxide synthesis in osteoblasts.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Benzoquinones; Bone Remodeling; Cell Line; Cytokines; Dexamethasone; Enzyme Induction; Estradiol; Gene Expression Regulation; Hematopoietic Cell Growth Factors; Lactams, Macrocyclic; Lipopolysaccharides; Mice; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Osteoblasts; Parathyroid Hormone; Peptide Fragments; Protein-Tyrosine Kinases; Quinones; Rifabutin; RNA, Messenger; Sodium Nitrite; Teriparatide; Vitamin D | 1995 |
Nitric oxide enhances resistance of SCID mice to mucosal candidiasis.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Candida albicans; Candidiasis; Cells, Cultured; Dose-Response Relationship, Drug; Female; Gastric Mucosa; Guanidines; Immunity, Innate; Interferon-gamma; Lipopolysaccharides; Macrophage Activation; Macrophages, Peritoneal; Male; Mice; Mice, SCID; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Recombinant Proteins | 1995 |
Involvement of nitric oxide in bone marrow-derived natural suppressor activity. Its dependence on IFN-gamma.
Topics: Acetylcysteine; Amino Acid Oxidoreductases; Animals; Antibodies, Monoclonal; Arginine; Bone Marrow; Cell Line; Immunity, Innate; Interferon-gamma; Lipopolysaccharides; Lymphocyte Activation; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Polymerase Chain Reaction; RNA, Messenger; T-Lymphocytes, Regulatory | 1995 |
Direct correlation between expression of endogenous inducible nitric oxide synthase and regression of M5076 reticulum cell sarcoma hepatic metastases in mice treated with liposomes containing lipopeptide CGP 31362.
Topics: Adjuvants, Immunologic; Amino Acid Oxidoreductases; Animals; Apoptosis; Arginine; Drug Carriers; Drug Interactions; Enzyme Activation; Enzyme Induction; Female; Interferon-gamma; Liposomes; Liver Neoplasms, Experimental; Lymphoma, Non-Hodgkin; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Oligopeptides; omega-N-Methylarginine; Peptide Fragments; Recombinant Proteins; RNA, Messenger | 1995 |
Renal actions of endothelin-1 and endothelin-3: interactions with the prostaglandin system and nitric oxide.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Diuresis; Dogs; Endothelins; Epoprostenol; Indomethacin; Kidney; Meclofenamic Acid; Natriuresis; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Prostaglandins; Renal Circulation; Thromboxane A2; Vasoconstriction; Vasodilation | 1995 |
TNF-alpha and IL-1 beta upregulate nitric oxide-dependent ciliary motility in bovine airway epithelium.
Topics: Amino Acid Oxidoreductases; Animals; Antibodies; Arginine; Bronchi; Cattle; Cell Survival; Cells, Cultured; Cilia; Culture Media, Conditioned; Epithelial Cells; Epithelium; Humans; Interleukin-1; Isoproterenol; Kinetics; Macrophages, Alveolar; Movement; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Recombinant Proteins; Time Factors; Tumor Necrosis Factor-alpha; Videotape Recording | 1995 |
Nitric oxide alters cytosolic potassium in cultured glomerular mesangial cells.
Topics: Acetylcholine; Amino Acid Oxidoreductases; Animals; Arginine; Cells, Cultured; Cytosol; Fluorescent Dyes; Glomerular Mesangium; Kinetics; Male; Membrane Potentials; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Potassium; Pyridinium Compounds; Rats | 1995 |
Endotoxin-induced contractile dysfunction in guinea pig hearts is not mediated by nitric oxide.
Topics: Adenine Nucleotides; Amino Acid Oxidoreductases; Animals; Arginine; Cerebellum; Chromatography, High Pressure Liquid; Citrulline; Coronary Circulation; Endotoxins; Energy Metabolism; Enzyme Induction; Guinea Pigs; Heart; Lipopolysaccharides; Magnetic Resonance Spectroscopy; Myocardial Contraction; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phosphocreatine; Vascular Resistance; Ventricular Function, Left | 1995 |
The inter-relationship between polyamines and the L-arginine nitric oxide pathway in the human placenta.
Topics: Amino Acid Oxidoreductases; Arginine; Cadaverine; Cell Line; Chorionic Villi; Female; Fetal Growth Retardation; Humans; Lipopolysaccharides; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Placenta; Polyamines; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, First; Pregnancy Trimester, Third; Putrescine; Reference Values; Spermidine; Spermine | 1995 |
Acute blockade of nitric oxide synthase inhibits renal vasodilation and hyperfiltration during pregnancy in chronically instrumented conscious rats.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cyclic GMP; Female; Glomerular Filtration Rate; Kidney; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Pregnancy; Pregnancy, Animal; Rats; Renal Circulation; Vasodilation | 1995 |
Role of macrophage-derived nitric oxide in suppression of lymphocyte proliferation during blood-stage malaria.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Base Sequence; DNA Primers; Female; Guanidines; Immune Tolerance; Lymphocyte Activation; Macrophages, Peritoneal; Malaria; Male; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Plasmodium chabaudi; Prostaglandins; Spleen | 1995 |
Elevated platelet calcium mobilization and nitric oxide synthase activity may reflect abnormalities in schizophrenic brain.
Topics: Adult; Amino Acid Oxidoreductases; Arginine; Blood Platelets; Brain; Calcium; Female; Humans; Kinetics; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Schizophrenia; Thrombin | 1995 |
Opioids inhibit the induction of nitric oxide synthase in J774 macrophages.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Amino Acid Oxidoreductases; Animals; Arginine; Cell Line; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Enzyme Induction; Lipopolysaccharides; Macrophages; Mice; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Nitric Oxide; Nitric Oxide Synthase; Oligopeptides; omega-N-Methylarginine; Pyrrolidines; Receptors, Opioid | 1995 |
Nitric oxide is important for mouse beta-cell line killing by peritoneal exudate cells obtained from cyclophosphamide treated non-obese diabetic mice.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Death; Cell Line; Cyclophosphamide; Cytotoxicity, Immunologic; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Female; Islets of Langerhans; Macrophages, Peritoneal; Mice; Mice, Inbred NOD; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine | 1995 |
Role of nitric oxide in penile erection and yawning induced by 5-HT1c receptor agonists in male rats.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Guanylate Cyclase; Injections; Injections, Intraventricular; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Paraventricular Hypothalamic Nucleus; Penile Erection; Piperazines; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists; Yawning | 1995 |
Leukotoxin, 9,10-epoxy-12-octadecenoate causes edematous lung injury via activation of vascular nitric oxide synthase.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Vessels; Enzyme Activation; Exotoxins; L-Lactate Dehydrogenase; Linoleic Acids; Lung; Male; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Oxyhemoglobins; Perfusion; Pulmonary Edema; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 1995 |
Endothelium-dependent relaxation of small arteries from essential hypertensive patients: mechanisms and comparison with normotensive subjects and with responses of vessels from spontaneously hypertensive rats.
Topics: Acetylcholine; Adult; Animals; Apamin; Arginine; Arterioles; Charybdotoxin; Endothelium, Vascular; Humans; Hypertension; In Vitro Techniques; Indomethacin; Male; Methylene Blue; Middle Aged; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Ouabain; Potassium Chloride; Rats; Rats, Inbred SHR; Scorpion Venoms; Tolbutamide; Vasoconstriction | 1995 |
Nitric oxide suppression of human hematopoiesis in vitro. Contribution to inhibitory action of interferon-gamma and tumor necrosis factor-alpha.
Topics: Amino Acid Oxidoreductases; Apoptosis; Arginine; Base Sequence; Benzamides; Bone Marrow Cells; Cells, Cultured; Colony-Forming Units Assay; Enzyme Induction; Hematopoiesis; Hematopoietic Stem Cells; Humans; Interferon-gamma; Molecular Sequence Data; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha | 1995 |
Nitric oxide production by Sertoli cells in response to cytokines and lipopolysaccharide.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cells, Cultured; Cytokines; Drug Interactions; Guanidines; Humans; Interferon-gamma; Interleukin-1; Lipopolysaccharides; Male; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Recombinant Proteins; RNA, Messenger; Sertoli Cells; Tumor Necrosis Factor-alpha | 1995 |
The killing of Leishmania major by human macrophages is mediated by nitric oxide induced after ligation of the Fc epsilon RII/CD23 surface antigen.
Topics: Amino Acid Oxidoreductases; Animals; Antibodies, Monoclonal; Antigens, CD; Arginine; Base Sequence; Cells, Cultured; Cytokines; DNA Primers; Gene Expression; Humans; Interferon-gamma; Interleukin-4; Leishmania major; Lipopolysaccharides; Macrophages; Molecular Sequence Data; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phagocytosis; Polymerase Chain Reaction; Receptors, IgE; Recombinant Proteins; RNA, Messenger; Superoxides; Tumor Necrosis Factor-alpha | 1995 |
Evidence of autocrine modulation of macrophage nitric oxide synthase by alpha-melanocyte-stimulating hormone.
Topics: alpha-MSH; Amino Acid Oxidoreductases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Base Sequence; Cell Line; DNA Primers; Gene Expression; Humans; Interferon-gamma; Lipopolysaccharides; Macrophages; Mice; Models, Biological; Molecular Sequence Data; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Polymerase Chain Reaction; Pro-Opiomelanocortin; Receptors, Corticotropin; Receptors, Melanocortin; Recombinant Proteins; RNA, Messenger; Salmonella typhi | 1995 |
Modulation of extraluminally induced vasoconstrictions by endothelium-derived nitric oxide in the canine basilar artery.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Basilar Artery; Dinoprost; Dogs; Endothelium, Vascular; Female; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Potassium; Vasoconstriction | 1995 |
Calcitonin gene-related peptide mediated neurogenic vasorelaxation in the isolated canine lingual artery.
Topics: Animals; Arginine; Benzopyrans; Calcitonin Gene-Related Peptide; Capsaicin; Cromakalim; Dogs; Electric Stimulation; Female; Glyburide; Humans; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Peptide Fragments; Potassium Channel Blockers; Potassium Channels; Propranolol; Pyrroles; Substance P; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Vasoconstriction; Vasodilator Agents | 1995 |
NG-methyl-L-arginine protects the guinea pig cochlea from the cytotoxic effects of pneumolysin.
Topics: Action Potentials; Amino Acid Oxidoreductases; Animals; Arginine; Bacterial Proteins; Cochlea; Cochlear Microphonic Potentials; Cytotoxins; Dizocilpine Maleate; Enzyme Inhibitors; Guinea Pigs; Microscopy, Electron, Scanning; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Receptors, N-Methyl-D-Aspartate; Streptolysins | 1995 |
Nitric oxide-mediated inactivation of mammalian ferrochelatase in vivo and in vitro: possible involvement of the iron-sulphur cluster of the enzyme.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Line; Cloning, Molecular; Enzyme Inhibitors; Escherichia coli; Ferrochelatase; Humans; Immunoblotting; Interferon-gamma; Iron-Sulfur Proteins; Lipopolysaccharides; Macrophages; Mammals; Mice; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Penicillamine; Recombinant Proteins; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents | 1995 |
Effects of nitric oxide synthase inhibition on myocardial capillary permeability and reactive hyperaemic response.
Topics: Acetylcholine; Amino Acid Oxidoreductases; Animals; Arginine; Capillary Permeability; Coronary Circulation; Dogs; Heart; Hyperemia; Myocardial Ischemia; NADPH Dehydrogenase; Nitric Oxide Synthase; omega-N-Methylarginine; Technetium Tc 99m Pentetate | 1995 |
Alpha 2-macroglobulin functions as a cytokine carrier to induce nitric oxide synthesis and cause nitric oxide-dependent cytotoxicity in the RAW 264.7 macrophage cell line.
Topics: alpha-Macroglobulins; Amino Acid Oxidoreductases; Animals; Apoptosis; Arginine; Carrier Proteins; Cell Line; Cell Membrane; Cell Survival; Cytokines; Cytoplasm; DNA; Enzyme Induction; Gene Expression; Gene Expression Regulation, Enzymologic; Genetic Techniques; Humans; Interferon-gamma; Kinetics; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Organelles; Recombinant Proteins; RNA, Messenger; Thymidine; Transforming Growth Factor beta | 1995 |
Protection against ischemic injury by nonvasoactive concentrations of nitric oxide synthase inhibitors in the perfused rabbit heart.
Topics: Adenosine Triphosphate; Amino Acid Oxidoreductases; Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glucose; Glycolysis; Magnetic Resonance Spectroscopy; Male; Myocardial Reperfusion Injury; Myocardium; NADPH Dehydrogenase; Nitric Oxide Synthase; omega-N-Methylarginine; Perfusion; Phosphocreatine; Rabbits; Time Factors | 1995 |
Effect of superoxide dismutase on nitric oxide production by RAW264 macrophages.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Line; Interferon-gamma; Lipopolysaccharides; Macrophage Activation; Macrophages; Mast-Cell Sarcoma; Mice; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Superoxide Dismutase | 1995 |
Interferon-gamma/tumour necrosis factor-alpha synergism as a mechanism for enhanced nitric oxide production following in vivo administration of muramyl dipeptide (MDP) to mice.
Topics: Acetylmuramyl-Alanyl-Isoglutamine; Amino Acid Oxidoreductases; Animals; Arginine; Female; Injections, Subcutaneous; Interferon Inducers; Interferon-gamma; Lymphocytes; Lymphokines; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Recombinant Proteins; Specific Pathogen-Free Organisms; Spleen; Tumor Necrosis Factor-alpha | 1995 |
Effects of inhibition of nitric oxide synthesis on TNF alpha serum levels in E. coli endotoxemic rats.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Escherichia coli Infections; Guanidines; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Toxemia; Tumor Necrosis Factor-alpha | 1995 |
Nitric oxide synthase activity is inducible in rat, but not rabbit alveolar macrophages, with a concomitant reduction in arginase activity.
Topics: Amino Acid Oxidoreductases; Animals; Arginase; Arginine; Citrulline; Cytokines; Dexamethasone; Enzyme Induction; Female; In Vitro Techniques; Lipopolysaccharides; Macrophages, Alveolar; Male; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Ornithine; Rabbits; Rats; Rats, Sprague-Dawley | 1995 |
Evidence for bidirectional changes in nitric oxide synthase activity in the rat striatum after excitotoxically (quinolinic acid) induced degeneration.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Glutamate Decarboxylase; Immunohistochemistry; Male; Microscopy, Electron; NADP; NADPH Dehydrogenase; Neostriatum; Nerve Degeneration; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Quinolinic Acid; Rats; Rats, Wistar; Subcellular Fractions | 1995 |
Modulation of cerebral arteriolar diameter by intraluminal flow and pressure.
Topics: Animals; Arginine; Arterioles; Cerebrovascular Circulation; Enzyme Inhibitors; In Vitro Techniques; Indomethacin; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Stress, Mechanical; Vascular Resistance | 1995 |
Endogenous and exogenous nitric oxide inhibits norepinephrine release from rat heart sympathetic nerves.
Topics: Animals; Arginine; Enzyme Inhibitors; Female; Heart; Immunohistochemistry; In Vitro Techniques; Male; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System | 1995 |
Endothelial release of nitric oxide contributes to the vasodilator effect of adenosine in humans.
Topics: Adenosine; Arginine; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Female; Forearm; Humans; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Plethysmography; Potassium Channels; Quinidine; Regional Blood Flow; Tolbutamide; Vasodilation; Vasodilator Agents; Verapamil | 1995 |
Nitric oxide inhibits the positive inotropic response to beta-adrenergic stimulation in humans with left ventricular dysfunction.
Topics: Adrenergic beta-Agonists; Arginine; Dobutamine; Enzyme Inhibitors; Female; Humans; Male; Middle Aged; Myocardial Contraction; Myocardium; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Stimulation, Chemical; Ventricular Dysfunction, Left | 1995 |
Antifungal mechanisms of activated murine bronchoalveolar or peritoneal macrophages for Histoplasma capsulatum.
Topics: Animals; Arginine; Histoplasma; Macrophage Activation; Macrophages; Macrophages, Alveolar; Macrophages, Peritoneal; Male; Mice; Mice, Inbred BALB C; Nitric Oxide; omega-N-Methylarginine | 1995 |
Nitric oxide modulates pepsinogen secretion induced by calcium-mediated agonist in guinea pig gastric chief cells.
Topics: Animals; Arginine; Calcium; Calmodulin; Carbachol; Cells, Cultured; Cholecystokinin; Citrulline; Cyclic GMP; Egtazic Acid; Gastric Mucosa; Gastrins; Guinea Pigs; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Pepsinogens; Terpenes; Thapsigargin | 1995 |
Attenuation of tolerance to, and physical dependence on, morphine in the rat by inhibition of nitric oxide synthase.
Topics: Animals; Arginine; Drug Implants; Drug Tolerance; Enzyme Inhibitors; Male; Morphine; Morphine Dependence; Naltrexone; Nitric Oxide Synthase; omega-N-Methylarginine; Pain Measurement; Rats; Rats, Sprague-Dawley | 1995 |
Production of reactive nitrogen intermediates (RNI) by peritoneal macrophages from rats with experimental autoimmune prostatitis (EAP).
Topics: Animals; Arginine; Autoimmune Diseases; Genitalia, Male; Immunization; Kidney; Lipopolysaccharides; Macrophages, Peritoneal; Male; Nitric Oxide; Nitrogen; omega-N-Methylarginine; Oxidants; Oxidative Stress; Prostatitis; Rats; Rats, Wistar; Tissue Extracts | 1995 |
Nitric oxide production during murine Lyme disease: lack of involvement in host resistance or pathology.
Topics: Animals; Arginine; Base Sequence; Female; Lyme Disease; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Molecular Sequence Data; Nitric Oxide; omega-N-Methylarginine; Species Specificity | 1995 |
Chronic transection of post-ganglionic parasympathetic and nasociliary nerves does not affect local cerebral blood flow in the rat.
Topics: Animals; Arginine; Autoradiography; Blood Gas Analysis; Blood Pressure; Cerebrovascular Circulation; Denervation; Enzyme Inhibitors; Male; Nasal Mucosa; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Sympathetic Fibers, Postganglionic; Vasodilation | 1995 |
Nebivolol vasodilates human forearm vasculature: evidence for an L-arginine/NO-dependent mechanism.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Antagonists; Adult; Arginine; Benzopyrans; Brachial Artery; Ethanolamines; Forearm; Humans; Infusions, Intravenous; Male; Nebivolol; Nitric Oxide; omega-N-Methylarginine; Regional Blood Flow; Stereoisomerism; Vasodilator Agents | 1995 |
Roles of prostaglandins, nitric oxide and the capsaicin-sensitive sensory nerves in gastroprotection produced by ecabet sodium.
Topics: 16,16-Dimethylprostaglandin E2; Abietanes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arginine; Capsaicin; Dinoprostone; Diterpenes; Drug Interactions; Ethanol; Gastric Mucosa; Indomethacin; Intestinal Mucosa; Male; Neurons, Afferent; Nitric Oxide; omega-N-Methylarginine; Prostaglandins; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity | 1995 |
Impaired endothelial function in patients with nephrotic range proteinuria.
Topics: Adult; Arginine; Endothelium, Vascular; Female; Forearm; Glomerulonephritis; Humans; Male; Nephrosis; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Plethysmography; Proteinuria; Reference Values; Regional Blood Flow; Serotonin | 1995 |
Endothelium-dependent vasorelaxation caused by various plant extracts.
Topics: Animals; Aorta; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Fruit; In Vitro Techniques; Magnoliopsida; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nuts; omega-N-Methylarginine; Phenylephrine; Plant Extracts; Radioimmunoassay; Rats; Spices; Tea; Vasoconstrictor Agents; Vegetables | 1995 |
Role of reactive nitrogen intermediates in the regulation of allogeneic skin graft survival in mice after portal vein pretransplant transfusion.
Topics: Animals; Arginine; Base Sequence; Cell Transplantation; Cytokines; Enzyme Activation; Enzyme Induction; Graft Survival; Isoantigens; Mice; Mice, Inbred Strains; Molecular Sequence Data; Nitric Oxide; Nitric Oxide Synthase; Nitrogen; omega-N-Methylarginine; Portal Vein; RNA, Messenger; Skin Transplantation; Spleen; Th2 Cells; Time Factors | 1995 |
Evidence of a role for endothelium-derived nitric oxide in the regulation of vascular tone during acute haemorrhage.
Topics: Acute Disease; Animals; Arginine; Cats; Endothelium, Vascular; Enzyme Inhibitors; Hemorrhage; Muscle Tonus; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Vascular Resistance | 1995 |
Induction of NG-monomethyl-L-arginine uptake: a mechanism for differential inhibition of NO synthases?
Topics: Animals; Arginine; Biological Transport; Cell Line; Citrulline; Cytokines; Endothelium, Vascular; Endotoxins; Humans; Kinetics; Macrophages; Mice; Nitric Oxide Synthase; omega-N-Methylarginine; Time Factors | 1995 |
Nitric oxide does not mediate autoregulation of retinal blood flow in newborn pig.
Topics: Animals; Animals, Newborn; Arginine; Arterioles; Female; Homeostasis; Hypercapnia; Hypotension; Hypoxia; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Retinal Vessels; Swine; Vasodilation; Vasomotor System | 1995 |
Effect of L-NMMA, cromakalim, and glibenclamide on cerebral blood flow in hypercapnia and hypoxia.
Topics: Animals; Arginine; Arteries; Benzopyrans; Cerebrovascular Circulation; Cromakalim; Glyburide; Hypercapnia; Hypoxia; Nitric Oxide Synthase; omega-N-Methylarginine; Pyrroles; Rats; Theophylline; Vasodilator Agents | 1995 |
Dependence and reversal of nitric oxide production on NF-kappa B in silica and lipopolysaccharide-induced macrophages.
Topics: Acetylcysteine; Alkaloids; Animals; Arginine; Base Sequence; Cell Line; Cell Nucleus; Enzyme Inhibitors; Indomethacin; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Molecular Sequence Data; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Oligonucleotide Probes; omega-N-Methylarginine; Protein Kinase C; Silicon Dioxide; Staurosporine; Tosylphenylalanyl Chloromethyl Ketone; Tyrosine | 1995 |
Essential role of NF-kappa B activation in silica-induced inflammatory mediator production in macrophages.
Topics: Animals; Arginine; Base Sequence; Cell Line; Consensus Sequence; DNA; Enzyme Induction; Gene Expression; Inflammation; Interleukin-1; Isoenzymes; Lipopolysaccharides; Macrophages, Alveolar; Mice; Molecular Sequence Data; NF-kappa B; Nitric Oxide Synthase; Oligodeoxyribonucleotides; omega-N-Methylarginine; Prostaglandin-Endoperoxide Synthases; Protease Inhibitors; RNA, Messenger; Silicon Dioxide; Tosylphenylalanyl Chloromethyl Ketone; Transcription, Genetic; Tumor Necrosis Factor-alpha; Tyrosine | 1995 |
Spin trapping agent, phenyl N-tert-butyl nitrone, inhibits induction of nitric oxide synthase in endotoxin-induced shock in mice.
Topics: Animals; Arginine; Blotting, Western; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Enzyme Induction; Enzyme Inhibitors; Lipopolysaccharides; Liver; Male; Mice; Mice, Inbred BALB C; Nitric Oxide; Nitric Oxide Synthase; Nitrogen Oxides; omega-N-Methylarginine; Shock, Septic; Spin Labels | 1995 |
Inhibition of nitric oxide (NO.) production in murine macrophages by flavones.
Topics: Animals; Arginine; Cell Survival; Concanavalin A; Enzyme Inhibitors; Flavonoids; Genistein; Isoflavones; Lipopolysaccharides; Macrophages; Macrophages, Peritoneal; Male; Mice; Mice, Inbred BALB C; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine | 1995 |
Inhibition of carbonic anhydrase by nitric oxide.
Topics: Acetazolamide; Animals; Arginine; Carbonic Anhydrase Inhibitors; Cattle; Enzyme Activation; Enzyme Inhibitors; Erythrocytes; Humans; In Vitro Techniques; Kinetics; Male; Nitric Oxide; omega-N-Methylarginine; Parietal Cells, Gastric; Rabbits | 1995 |
Hypersecretion of mucin in response to inflammatory mediators by guinea pig tracheal epithelial cells in vitro is blocked by inhibition of nitric oxide synthase.
Topics: Animals; Arginine; Cells, Cultured; Enzyme Inhibitors; Guinea Pigs; Histamine; Inflammation Mediators; Mucins; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Activating Factor; Secretory Rate; Superoxides; Trachea; Tumor Necrosis Factor-alpha | 1995 |
Nitric oxide-dependent killing of Candida albicans by murine peritoneal cells during an experimental infection.
Topics: Animals; Arginine; Candida albicans; Candidiasis; Female; In Vitro Techniques; Mice; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Peritoneal Cavity; Phagocytes; Phagocytosis; Reactive Oxygen Species | 1995 |
Characterization of the effects of two new arginine/citrulline analogues on constitutive and inducible nitric oxide synthases in rat aorta.
Topics: Acetylcholine; Adenosine Diphosphate; Analysis of Variance; Animals; Aorta, Thoracic; Arginine; Calcimycin; Citrulline; Dose-Response Relationship, Drug; Enzyme Induction; Enzyme Inhibitors; Ionophores; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phenylephrine; Rats; Rats, Wistar; Thiourea; Vasoconstrictor Agents | 1995 |
Polydeoxyribonucleotides and nitric oxide release from guinea-pig hearts during ischaemia and reperfusion.
Topics: Acetylcholine; Animals; Arginine; Arrhythmias, Cardiac; Chemical Fractionation; Coronary Circulation; Disease Models, Animal; DNA; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibrinolytic Agents; Guinea Pigs; Male; Molecular Weight; Myocardial Reperfusion Injury; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Polydeoxyribonucleotides | 1995 |
Accumulation of endogenous inhibitors for nitric oxide synthesis and decreased content of L-arginine in regenerated endothelial cells.
Topics: Acetylcholine; Animals; Arginine; Carotid Arteries; Chromatography; Dose-Response Relationship, Drug; Endothelium; Enzyme Inhibitors; Fluorescence; Male; Microscopy, Electron, Scanning; Nitric Oxide; omega-N-Methylarginine; Rabbits | 1995 |
Role of nitric oxide in disruption of the blood-brain barrier during acute hypertension.
Topics: Acute Disease; Animals; Arginine; Blood-Brain Barrier; Brain; Enzyme Inhibitors; Fluorescein-5-isothiocyanate; Hypertension; Male; Metabolic Clearance Rate; Microcirculation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phenylephrine; Rats | 1995 |
Role of nitric oxide in hemostatic system activation in vivo in humans.
Topics: Administration, Inhalation; Adult; Arginine; beta-Thromboglobulin; Bleeding Time; Enzyme Inhibitors; Hemostasis; Humans; Male; Nitric Oxide; omega-N-Methylarginine; Prothrombin; Thromboxane B2 | 1995 |
L-arginine reverses low coronary reflow and enhances postischaemic recovery of cardiac mechanical function.
Topics: Animals; Arginine; Coronary Circulation; Heart; Heart Arrest, Induced; Male; Myocardial Ischemia; Myocardial Reperfusion; Nitric Oxide; omega-N-Methylarginine; Perfusion; Rats; Rats, Sprague-Dawley; Regional Blood Flow | 1995 |
L-NMMA blocks carbachol-induced increases in cGMP levels but not decreases in tension in the presence of forskolin in rabbit papillary muscles.
Topics: Animals; Arginine; Carbachol; Colforsin; Cyclic GMP; Female; Guanylate Cyclase; In Vitro Techniques; Male; Muscarinic Agonists; Myocardial Contraction; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Papillary Muscles; Rabbits | 1995 |
Inhibition of nitric oxide synthesis protects the isolated working rabbit heart from ischaemia-reperfusion injury.
Topics: Animals; Arginine; Glycogen; Heart; Lactates; Lactic Acid; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Perfusion; Rabbits | 1995 |
Effect of insulin on acetylcholine-induced vasodilation in normotensive subjects and patients with essential hypertension.
Topics: Acetylcholine; Arginine; Case-Control Studies; Endothelium, Vascular; Enzyme Inhibitors; Female; Forearm; Humans; Hypertension; Insulin; Male; Middle Aged; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Ouabain; Regional Blood Flow; Sodium-Potassium-Exchanging ATPase; Time Factors; Vasodilation; Vasodilator Agents | 1995 |
Endothelin at pathophysiological concentrations mediates coronary vasoconstriction via the endothelin-A receptor.
Topics: Animals; Arginine; Azepines; Coronary Vessels; Dogs; Endothelin Receptor Antagonists; Endothelins; Enzyme Inhibitors; Indoles; Nitric Oxide Synthase; omega-N-Methylarginine; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Vasoconstriction; Viper Venoms | 1995 |
Inhibition of nitric oxide synthesis in the forearm arterial bed of patients with advanced cirrhosis.
Topics: Arginine; Enzyme Inhibitors; Female; Forearm; Humans; Infusions, Intra-Arterial; Liver Cirrhosis, Alcoholic; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; omega-N-Methylarginine; Regional Blood Flow; Vasoconstriction; Vasoconstrictor Agents | 1995 |
Chronic angiotensin-converting enzyme inhibition and endothelial function of rat aorta.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Arginine; Bradykinin; Cyclic GMP; Drug Synergism; Endothelium, Vascular; Hydralazine; Male; Nitric Oxide; omega-N-Methylarginine; Peptidyl-Dipeptidase A; Ramipril; Rats; Rats, Wistar; Vasodilation | 1995 |
Does nitric oxide synthesis really contribute to systemic blood pressure control?
Topics: Adult; Arginine; Blood Pressure; Humans; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine | 1995 |
Does the antiarrhythmic effect of ischemic preconditioning in rats involve the L-arginine nitric oxide pathway?
Topics: Animals; Arginine; Arrhythmias, Cardiac; Blood Pressure; Coronary Vessels; Electrocardiography; Male; Myocardial Ischemia; Myocardial Reperfusion; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Wistar | 1995 |
Platelet rap1B phosphorylation is a sensitive marker for the action of cyclic AMP- and cyclic GMP-increasing platelet inhibitors and vasodilators.
Topics: Arginine; Autoradiography; Biomarkers; Blood Platelets; Blood Protein Electrophoresis; Blotting, Western; Cells, Cultured; Cyclic AMP; Cyclic GMP; Epoprostenol; GTP-Binding Proteins; Humans; In Vitro Techniques; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Phosphorylation; Platelet Aggregation Inhibitors; rap GTP-Binding Proteins; Signal Transduction; Vasodilator Agents | 1995 |
A role for gamma interferon-induced nitric oxide in pulmonary clearance of Cryptococcus neoformans.
Topics: Animals; Arginine; Cells, Cultured; Cryptococcosis; Immunocompetence; Interferon-gamma; Leukocytes; Lung; Lymphocyte Activation; Macrophages; Mice; Mice, SCID; Nitrates; Nitric Oxide; Nitrites; omega-N-Methylarginine; Stem Cells | 1995 |
Direct measurement of nitric oxide in human beings.
Topics: Acetylcholine; Adult; Arginine; Bradykinin; Dose-Response Relationship, Drug; Electrochemistry; Humans; Male; Nitric Oxide; omega-N-Methylarginine; Veins | 1995 |
Role of nitric oxide in restitution of injured guinea pig gastric mucosa in vitro.
Topics: Animals; Arginine; Bicarbonates; Cyclic GMP; Dibutyryl Cyclic GMP; Gastric Mucosa; Guinea Pigs; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Mannitol; Methylene Blue; Microscopy, Electron; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Saline Solution, Hypertonic; Stereoisomerism; Time Factors | 1995 |
Role of nitric oxide in regulation of vascular resistance in postnatal intestine.
Topics: Aging; Analysis of Variance; Animals; Animals, Newborn; Arginine; Blood Pressure; Cyclic GMP; Endothelium, Vascular; In Vitro Techniques; Infusions, Intra-Arterial; Intestines; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Oxygen; Partial Pressure; Potassium Chloride; Regional Blood Flow; Swine; Vascular Resistance | 1995 |
Glomerular and tubular interactions between renal adrenergic activity and nitric oxide.
Topics: Analysis of Variance; Angiotensin II; Animals; Arginine; Capillaries; Cyclic GMP; Denervation; Glomerular Filtration Rate; Kidney; Kidney Glomerulus; Kidney Tubules; Male; Models, Biological; Models, Theoretical; Nephrons; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Wistar; Renal Circulation | 1995 |
5-Hydroxytryptamine-induced NO-dependent relaxation in isolated strips of monkey popliteal lymph nodes.
Topics: Animals; Arginine; Aspirin; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Ketanserin; Lymph Nodes; Macaca; Male; Methiothepin; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; omega-N-Methylarginine; Serotonin; Serotonin Receptor Agonists | 1995 |
Endothelial-dependent vasodilation is preserved in non-insulin-dependent Zucker fatty diabetic rats.
Topics: Acetylcholine; Adenosine Diphosphate; Animals; Arginine; Arterioles; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; In Vitro Techniques; Intestines; Least-Squares Analysis; Male; Nitric Oxide; Nitroprusside; Obesity; omega-N-Methylarginine; Rats; Rats, Zucker; Thinness; Vasodilation | 1995 |
On-line measurement of nitric oxide generation in buffer-perfused rabbit lungs.
Topics: Animals; Arginine; Calcimycin; Female; In Vitro Techniques; Luminescent Measurements; Lung; Male; Nitrates; Nitric Oxide; Nitrites; omega-N-Methylarginine; Oxygen; Perfusion; Rabbits; Vanadium Compounds | 1995 |
Nitric oxide generation and hypoxic vasoconstriction in buffer-perfused rabbit lungs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Angiotensin II; Animals; Arginine; Female; Hypoxia; In Vitro Techniques; Lung; Male; Nitric Oxide; omega-N-Methylarginine; Perfusion; Prostaglandin Endoperoxides, Synthetic; Pulmonary Circulation; Rabbits; Thromboxane A2; Vasoconstriction | 1995 |
Role of hippocampal nitric oxide in memory retention in rats.
Topics: Adenosine Diphosphate Ribose; Animals; Arginine; Hippocampus; Male; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Retention, Psychology | 1995 |
Selective inhibition of nitric oxide production during cardiac allograft rejection causes a small increase in graft survival.
Topics: Animals; Arginine; Graft Rejection; Graft Survival; Heart Transplantation; Myocardium; Nitrates; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred BN; Rats, Inbred Lew; Transplantation, Homologous | 1995 |
Arginine enhances glycogen synthesis in response to insulin in 3T3-L1 adipocytes.
Topics: 3T3 Cells; Adenosine Triphosphate; Adipocytes; Animals; Arginine; Biological Transport; Cell Line; Glucose; Glutamic Acid; Glycogen; Insulin; Lysine; Mice; Nitric Oxide; omega-N-Methylarginine | 1995 |
Role of renal nerves in natriuresis of L-NMMA infusion in SHR and WKY rats.
Topics: Animals; Arginine; Denervation; Hypertension; Kidney; Male; Natriuresis; Nephrectomy; Nervous System; Nitric Oxide; omega-N-Methylarginine; Phosphates; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1995 |
Role of basal and stimulated release of nitric oxide in the regulation of radial artery caliber in humans.
Topics: Acetylcholine; Adolescent; Adult; Arginine; Blood Pressure; Female; Heart Rate; Humans; Male; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Radial Artery; Vascular Resistance | 1995 |
Insulin-mediated skeletal muscle vasodilation contributes to both insulin sensitivity and responsiveness in lean humans.
Topics: Adult; Arginine; Body Composition; Body Mass Index; Fasting; Glucose; Glucose Clamp Technique; Humans; Insulin; Insulin Resistance; Leg; Muscle, Skeletal; omega-N-Methylarginine; Regional Blood Flow; Vasodilation | 1995 |
Transforming growth factor-beta stimulates arginase activity in macrophages. Implications for the regulation of macrophage cytotoxicity.
Topics: Animals; Arginase; Arginine; Cells, Cultured; Cytotoxicity, Immunologic; Macrophages; Male; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta | 1995 |
Vascular function in the forearm of hypercholesterolaemic patients off and on lipid-lowering medication.
Topics: Adult; Arginine; Blood Pressure; Cholesterol; Cholestyramine Resin; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Forearm; Humans; Hyperlipoproteinemia Type II; Hypolipidemic Agents; Infusions, Intravenous; Lovastatin; Male; Nitroprusside; omega-N-Methylarginine; Regional Blood Flow; Serotonin; Simvastatin; Vasodilation | 1995 |
Direct in vivo observation of subendocardial arteriolar response during reactive hyperemia.
Topics: Adenosine; Animals; Arginine; Arterioles; Coronary Circulation; Coronary Vessels; Dogs; Female; Glyburide; Hyperemia; Male; Nitric Oxide; omega-N-Methylarginine; Potassium Channels; Theophylline; Vasodilation | 1995 |
In vivo regulation of replicative Legionella pneumophila lung infection by endogenous tumor necrosis factor alpha and nitric oxide.
Topics: Animals; Arginine; Female; Legionella pneumophila; Legionnaires' Disease; Lung; Mice; Nitric Oxide; omega-N-Methylarginine; Tumor Necrosis Factor-alpha | 1995 |
Killing of Histoplasma capsulatum by macrophage colony stimulating factor-treated human monocyte-derived macrophages: role for reactive oxygen intermediates.
Topics: Arginine; Catalase; Dose-Response Relationship, Immunologic; Free Radical Scavengers; Histoplasma; Humans; Macrophage Colony-Stimulating Factor; Macrophages; Monocytes; Nitric Oxide; omega-N-Methylarginine; Reactive Oxygen Species; Recombinant Proteins; Superoxide Dismutase | 1995 |
Adenosine enhances nitric oxide production by vascular endothelial cells.
Topics: Adenosine; Animals; Arginine; Carotid Arteries; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Nitric Oxide; omega-N-Methylarginine; Saphenous Vein; Swine; Theophylline | 1995 |
Hypoxia decreases endothelin-1 synthesis by rat lung endothelial cells.
Topics: Animals; Arginine; Carbon Monoxide; Endothelins; Endothelium, Vascular; Hypoxia; Nitric Oxide; omega-N-Methylarginine; Pulmonary Artery; Rats | 1995 |
Oestrogen relaxes human epicardial coronary arteries through non-endothelium-dependent mechanisms.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adolescent; Adult; Arginine; Child; Child, Preschool; Coronary Vessels; Endothelium, Vascular; Enzyme Inhibitors; Estradiol; Estrogen Replacement Therapy; Female; Humans; In Vitro Techniques; Indomethacin; Infant; Male; Middle Aged; Myocardial Ischemia; omega-N-Methylarginine; Prostaglandin Endoperoxides, Synthetic; Sex Factors; Thromboxane A2; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 1995 |
Basal release of endothelium-derived nitric oxide plays an important role in the prevention of afterload mismatch in acute left ventricular dysfunction.
Topics: Acute Disease; Analysis of Variance; Animals; Arginine; Blood Pressure Determination; Coronary Thrombosis; Dogs; Echocardiography; Endothelium, Vascular; Enzyme Inhibitors; Hemodynamics; Microspheres; Nitric Oxide; omega-N-Methylarginine; Time Factors; Ventricular Dysfunction, Left | 1995 |
Detection of nitric oxide production in mice by spin-trapping electron paramagnetic resonance spectroscopy.
Topics: Animals; Arginine; Chelating Agents; Electron Spin Resonance Spectroscopy; Female; Ferrous Compounds; Kidney; Lipopolysaccharides; Liver; Mice; Mice, Inbred ICR; Nitrates; Nitric Oxide; Nitrites; Nitrogen Isotopes; omega-N-Methylarginine; Shock, Septic; Sorbitol; Spin Labels; Thiocarbamates | 1995 |
NG-nitro L-arginine methyl ester and other alkyl esters of arginine are muscarinic receptor antagonists.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Binding, Competitive; Brain; Colon; Coronary Vessels; Dogs; Female; Guinea Pigs; Heart Atria; In Vitro Techniques; Male; Muscarinic Antagonists; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Rabbits; Radioligand Assay; Submandibular Gland | 1993 |
Control of cardiac muscle cell function by an endogenous nitric oxide signaling system.
Topics: Aging; Amino Acid Oxidoreductases; Animals; Animals, Newborn; Arginine; Carbachol; Cells, Cultured; Cyclic GMP; Heart; Heart Rate; Heart Ventricles; Isoproterenol; Methylene Blue; Myocardial Contraction; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Oxyhemoglobins; Rats; Signal Transduction | 1993 |
Pharmacologic intervention of skin vasospasm and ischemic necrosis in pigs.
Topics: Adrenergic alpha-Antagonists; Animals; Arginine; Dose-Response Relationship, Drug; Ergolines; In Vitro Techniques; Ischemia; Ketanserin; Necrosis; omega-N-Methylarginine; Prostaglandin H2; Prostaglandins H; Regional Blood Flow; Serotonin; Serotonin Antagonists; Skin; Surgical Flaps; Swine; Thromboxane A2; Vasoconstriction | 1993 |
Ca2+/calmodulin-dependent nitric oxide synthase activity in the human cervix carcinoma cell line ME-180.
Topics: Amino Acid Oxidoreductases; Arginine; Calcium; Calmodulin; Cyclic GMP; Female; Humans; Interferon-gamma; Kinetics; Lipopolysaccharides; Nitric Oxide Synthase; omega-N-Methylarginine; Pteridines; Recombinant Proteins; Tumor Cells, Cultured; Uterine Cervical Neoplasms | 1993 |
Prevention of diabetic vascular dysfunction by guanidines. Inhibition of nitric oxide synthase versus advanced glycation end-product formation.
Topics: Aldehyde Reductase; Amino Acid Oxidoreductases; Animals; Arginine; Benzothiazoles; Blood Pressure; Body Weight; Capillary Permeability; Citrulline; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Glycation End Products, Advanced; Guanidines; Imidazoles; Imidazolidines; Inositol; Iodine Radioisotopes; Male; Methylguanidine; Naphthalenes; Nitric Oxide Synthase; omega-N-Methylarginine; Phthalazines; Rats; Rats, Sprague-Dawley; Retina; Sciatic Nerve; Serum Albumin, Bovine; Sorbitol; Thiazoles; Uvea | 1993 |
Marked regional heterogeneity in the magnitude of EDRF/NO-mediated vascular tone in awake rats.
Topics: Animals; Arginine; Blood Gas Analysis; Cardiac Output; Hemodynamics; In Vitro Techniques; Male; Muscle Tonus; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Wistar; Regional Blood Flow; Vascular Resistance | 1993 |
Adaptation to increased dietary salt intake in the rat. Role of endogenous nitric oxide.
Topics: Adaptation, Physiological; Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Glomerular Filtration Rate; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Renal Circulation; Sodium, Dietary | 1993 |
Anti-nociceptive activity of nitric oxide synthase inhibitors in the mouse: dissociation between the effect of L-NAME and L-NMMA.
Topics: Amino Acid Oxidoreductases; Analgesics; Animals; Arginine; Brain; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Injections, Intraventricular; Male; Mice; Mice, Inbred Strains; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine | 1993 |
Role of NO on pressure-natriuresis in Wistar-Kyoto and spontaneously hypertensive rats.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Hypertension; Male; Natriuresis; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Circulation | 1993 |
Cytotoxicity of activated rat macrophages against syngeneic islet cells is arginine-dependent, correlates with citrulline and nitrite concentrations and is identical to lysis by the nitric oxide donor nitroprusside.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Cells, Cultured; Citrulline; Cyclic GMP; Female; Islets of Langerhans; Kinetics; Macrophage Activation; Macrophages; Male; Nitric Oxide; Nitrites; Nitroprusside; omega-N-Methylarginine; Rats; Rats, Wistar; Thionucleotides | 1993 |
IL-1 beta-induced inhibition of beta-cell function is mediated through nitric oxide.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cells, Cultured; Insulin; Insulin Secretion; Interleukin-1; Islets of Langerhans; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Inbred Lew | 1993 |
Endogenous vasoactive intestinal peptide and nitric oxide modulate cholinergic neurotransmission in guinea-pig trachea.
Topics: Acetylcholine; Amino Acid Oxidoreductases; Animals; Arginine; Bronchi; Chymotrypsin; Electric Stimulation; Guinea Pigs; Male; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Synaptic Transmission; Trachea; Vasoactive Intestinal Peptide | 1993 |
Nitric oxide synthase inhibition reverses arteriolar hyporesponsiveness to catecholamines in septic rats.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Arterioles; Infections; Male; Muscles; Nitric Oxide Synthase; Norepinephrine; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley | 1993 |
Modulation of airway epithelial cell ciliary beat frequency by nitric oxide.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Bradykinin; Bronchi; Cattle; Cilia; Epithelium; In Vitro Techniques; Isomerism; Isoproterenol; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Substance P | 1993 |
Endothelin-1 in the rabbit: interactions with cyclo-oxygenase and NO-synthase products.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Cyclooxygenase Inhibitors; Endothelins; Female; Glomerular Filtration Rate; Indomethacin; Male; Methylene Blue; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Pulse; Rabbits; Renal Circulation | 1993 |
The antioxidant properties of an inhibitor of nitric oxide synthase.
Topics: Amino Acid Oxidoreductases; Animals; Antioxidants; Arginine; Cells, Cultured; Free Radicals; Lipoproteins, LDL; Mice; Nitric Oxide Synthase; omega-N-Methylarginine | 1993 |
Cytokine toxicity and induction of NO synthase activity in cultured mouse hepatocytes.
Topics: Adenosine Triphosphate; Amino Acid Oxidoreductases; Animals; Arginine; Carmustine; Cell Survival; Cells, Cultured; Enzyme Induction; Glutathione; Interferon-gamma; Liver; Male; Mice; Nitric Oxide Synthase; omega-N-Methylarginine; Tumor Necrosis Factor-alpha | 1993 |
Irreversible inactivation of macrophage and brain nitric oxide synthase by L-NG-methylarginine requires NADPH-dependent hydroxylation.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Brain; Cell Line; Chromatography, High Pressure Liquid; Citrulline; Humans; Hydroxylation; Kinetics; Macrophages; Mice; NADP; Nitric Oxide Synthase; omega-N-Methylarginine; Oxidation-Reduction; Recombinant Proteins | 1993 |
L-NG-nitro arginine p-nitroanilide (L-NAPNA) is anti-nociceptive in the mouse.
Topics: Amino Acid Oxidoreductases; Analgesics; Anilides; Animals; Aorta, Thoracic; Arginine; Blood Pressure; Brain; Formaldehyde; In Vitro Techniques; Male; Mice; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Pain; Rabbits; Rats; Rats, Sprague-Dawley | 1993 |
Involvement of nitric oxide in long-term potentiation in the dentate gyrus in vivo.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Hippocampus; Male; Neuronal Plasticity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Inbred Strains | 1993 |
Inhibitors of nitric oxide synthetase prevent castor-oil-induced diarrhoea in the rat.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Body Fluids; Castor Oil; Diarrhea; Electrolytes; Gastrointestinal Transit; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Wistar | 1993 |
IL1 and TNF alpha induce cGMP formation in C6 astrocytoma cells via the nitridergic pathway.
Topics: 1-Methyl-3-isobutylxanthine; Arginine; Astrocytoma; Cyclic GMP; Interleukin-1; Nitrites; omega-N-Methylarginine; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1993 |
Induction by endotoxin of nitric oxide synthase in the rat mesentery: lack of effect on action of vasoconstrictors.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amino Acid Oxidoreductases; Animals; Arginine; Brain; Calcium; Endothelins; Endotoxins; Enzyme Induction; In Vitro Techniques; Lipopolysaccharides; Male; Mesentery; NADP; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Phenylephrine; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Sprague-Dawley; Rats, Wistar; Serotonin; Vasoconstrictor Agents | 1993 |
Nifedipine inhibits the induction of nitric oxide synthase by bacterial lipopolysaccharide.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Line; Cycloheximide; Dexamethasone; Enzyme Induction; Hemodynamics; Lipopolysaccharides; Lung; Macrophages; Male; Mice; Muscle, Smooth; Nifedipine; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Rats; Rats, Wistar | 1993 |
Nitric oxide synthase inhibitors attenuate human monocyte chemotaxis in vitro.
Topics: Amino Acid Oxidoreductases; Arginine; Canavanine; Cells, Cultured; Chemotaxis; Dibutyryl Cyclic GMP; Humans; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine | 1993 |
Vasoactive intestinal peptide stimulation of cyclic guanosine monophosphate formation: further evidence for a role of nitric oxide synthase and cytosolic guanylate cyclase in rat pinealocytes.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cyclic GMP; Cytosol; Drug Synergism; Guanylate Cyclase; Methylene Blue; Nitric Oxide Synthase; omega-N-Methylarginine; Phenylephrine; Pineal Gland; Rats; Vasoactive Intestinal Peptide | 1993 |
Nerve mediated relaxation of the human internal anal sphincter: the role of nitric oxide.
Topics: Aged; Aged, 80 and over; Amino Acid Oxidoreductases; Anal Canal; Arginine; Dose-Response Relationship, Drug; Electric Stimulation; Female; Humans; Male; Middle Aged; Muscle Contraction; Neurotransmitter Agents; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Oxyhemoglobins | 1993 |
Activated human polymorphonuclear leukocytes elicit endothelium-dependent contraction in isolated pig coronary arteries.
Topics: Animals; Arginine; Benzoquinones; Coronary Vessels; Endothelium, Vascular; Free Radicals; Humans; In Vitro Techniques; Indomethacin; Lipoxygenase Inhibitors; Luminescent Measurements; Muscle, Smooth, Vascular; Neutrophils; Nitric Oxide; omega-N-Methylarginine; Oxygen Consumption; Superoxide Dismutase; Swine; Zymosan | 1993 |
Evidence for induction of nonendothelial NO synthase in aortas of cholesterol-fed rabbits.
Topics: Amino Acid Oxidoreductases; Animals; Aorta; Arginine; Cholesterol, Dietary; Endothelium, Vascular; Enzyme Induction; Male; Muscle Contraction; Nitric Oxide Synthase; Nitroarginine; Norepinephrine; omega-N-Methylarginine; Rabbits; Serotonin | 1993 |
Central inhibition of nitric oxide synthase preferentially augments release of oxytocin during dehydration.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Dehydration; Male; Nerve Tissue Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Oxytocin; Paraventricular Hypothalamic Nucleus; Pituitary Gland, Posterior; Rats; Rats, Sprague-Dawley; Supraoptic Nucleus; Vasopressins | 1993 |
What are the types and cellular sources of free radicals in the pathogenesis of type 1 (insulin-dependent) diabetes mellitus?
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cyclic GMP; Diabetes Mellitus, Type 1; Free Radicals; Humans; Insulinoma; Interferon-gamma; Interleukin-1; Islets of Langerhans; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Pancreatic Neoplasms; Rats; Tumor Cells, Cultured | 1993 |
Nitric oxide-generating system as an autocrine mechanism in human polymorphonuclear leucocytes.
Topics: 1-Methyl-3-isobutylxanthine; Arginine; Biological Transport; Citrulline; Cyclic GMP; Endothelins; Humans; In Vitro Techniques; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitric Oxide; Nitroprusside; omega-N-Methylarginine | 1993 |
Nitric oxide synthase inhibitors prevent apomorphine- and oxytocin-induced penile erection and yawning in male rats.
Topics: Amino Acid Oxidoreductases; Animals; Apomorphine; Arginine; Cerebral Ventricles; Dose-Response Relationship, Drug; Injections, Intravenous; Injections, Intraventricular; Male; Nitric Oxide Synthase; omega-N-Methylarginine; Oxytocin; Penile Erection; Rats; Rats, Sprague-Dawley; Stereoisomerism; Stereotaxic Techniques; Yawning | 1993 |
Induction of nitric oxide synthase gene by interleukin in vascular smooth muscle cells.
Topics: Alkaloids; Amino Acid Oxidoreductases; Animals; Arginine; Base Sequence; Blotting, Northern; Calmodulin; Cells, Cultured; Cycloheximide; Dactinomycin; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Induction; Interleukin-1; Molecular Sequence Data; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Polymerase Chain Reaction; Protein Kinase C; Rats; Recombinant Proteins; RNA, Messenger; Staurosporine; Sulfonamides | 1993 |
Endothelium-dependent effects of substance P and calcitonin gene-related peptide on mouse pial arterioles.
Topics: Animals; Arginine; Arterioles; Calcitonin Gene-Related Peptide; Endothelium, Vascular; Evans Blue; Indomethacin; Lasers; Male; Mice; Mice, Inbred ICR; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Pia Mater; Substance P; Vasodilation | 1993 |
Regional differences in the vasodilator response to vasopressin in canine cerebral arteries in vivo.
Topics: Angiography; Animals; Arginine; Cerebral Arteries; Circle of Willis; Dogs; Dose-Response Relationship, Drug; Female; Male; Nitric Oxide; omega-N-Methylarginine; Regional Blood Flow; Substance P; Vasoactive Intestinal Peptide; Vasodilation; Vasopressins; Vertebral Artery | 1993 |
Induction of nitric oxide synthase in human mesangial cells.
Topics: Amino Acid Oxidoreductases; Arginine; Cell Survival; Cells, Cultured; Cycloheximide; Cytokines; Dexamethasone; Enzyme Induction; Glomerular Mesangium; Humans; Interferon-gamma; Interleukin-1; Kinetics; Lipopolysaccharides; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Tumor Necrosis Factor-alpha | 1993 |
Nitric oxide synthase activity in ulcerative colitis and Crohn's disease.
Topics: Adult; Aged; Amino Acid Oxidoreductases; Arginine; Capillary Permeability; Colitis, Ulcerative; Colon; Crohn Disease; Egtazic Acid; Female; Humans; In Vitro Techniques; Intestinal Mucosa; Male; Middle Aged; Nitric Oxide Synthase; omega-N-Methylarginine; Vasodilation | 1993 |
Suppression of arthritis by an inhibitor of nitric oxide synthase.
Topics: Acute Disease; Amino Acid Oxidoreductases; Animals; Arginine; Arthritis; Cell Wall; Culture Techniques; Female; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Streptococcus; Synovial Membrane | 1993 |
Regulation of gall bladder motility by the arginine-nitric oxide pathway in guinea pigs.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Bethanechol Compounds; Cholecystokinin; Endotoxins; Gallbladder; Guinea Pigs; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Pressure; Second Messenger Systems | 1993 |
Nitric oxide activates cyclooxygenase enzymes.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Line; Cyclic GMP; Dinoprostone; Enzyme Activation; Guanidines; Humans; Indomethacin; Mice; Nitrates; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Prostaglandin-Endoperoxide Synthases; Recombinant Proteins | 1993 |
Tumor necrosis factor alpha inhibits contractions to sympathetic nerve stimulation by a nitric oxide-dependent mechanism.
Topics: Acetylcholine; Adrenal Glands; Amino Acid Oxidoreductases; Animals; Arginine; Cattle; Cells, Cultured; Chromaffin System; Electric Stimulation; Muscle Contraction; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Pulmonary Artery; Sympathetic Nervous System; Tumor Necrosis Factor-alpha | 1993 |
Interactions of nitric oxide synthase inhibitors and dexamethasone with alpha-adrenoceptor-mediated responses in rat aorta.
Topics: Adrenergic alpha-Antagonists; Amino Acid Oxidoreductases; Animals; Aorta, Thoracic; Arginine; Dexamethasone; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Norepinephrine; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha | 1993 |
Impairment of pulmonary-artery endothelium-dependent relaxation in chronic obstructive lung disease is not due to dysfunction of endothelial cell membrane receptors nor to L-arginine deficiency.
Topics: Acetylcholine; Adenosine Diphosphate; Adult; Aged; Amino Acid Oxidoreductases; Arginine; Blood Gas Analysis; Calcimycin; Cell Membrane; Endothelium, Vascular; Female; Humans; In Vitro Techniques; Lung Diseases, Obstructive; Male; Middle Aged; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide Synthase; omega-N-Methylarginine; Pulmonary Artery; Respiratory Function Tests | 1993 |
Prevention of nitric oxide synthase induction in vascular smooth muscle cells by microtubule depolymerizing agents.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Colchicine; Cyclic GMP; Cytoskeleton; Enzyme Induction; In Vitro Techniques; Interleukin-1; Lipopolysaccharides; Microtubules; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitroprusside; Nocodazole; omega-N-Methylarginine; Rats; Rats, Wistar | 1993 |
Involvement of nitric oxide synthase in the delayed vasodilator response to ultraviolet light irradiation of rat skin in vivo.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Canavanine; Clobetasol; Cyclooxygenase Inhibitors; Indomethacin; Laser-Doppler Flowmetry; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Skin; Ultraviolet Rays; Vasodilation | 1993 |
Nitric oxide modulates lymphocyte proliferation but not secretion of IL-2.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Division; Cells, Cultured; Concanavalin A; Interleukin-1; Interleukin-2; Lymphocyte Activation; Lymphocytes; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Spleen | 1993 |
Nitric oxide modulates the release of vasopressin from rat hypothalamic explants.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Arginine Vasopressin; Hypothalamus; Male; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Potassium Chloride; Rats; Rats, Wistar | 1993 |
A new approach in the treatment of hypotension in human septic shock by NG-monomethyl-L-arginine, an inhibitor of the nitric oxide synthetase.
Topics: Adult; Amino Acid Oxidoreductases; Arginine; Blood Pressure; Cardiac Output; Combined Modality Therapy; Critical Care; Dose-Response Relationship, Drug; Humans; Hypotension; Male; Necrosis; Nitric Oxide Synthase; omega-N-Methylarginine; Pancreatitis; Pseudomonas aeruginosa; Pseudomonas Infections; Recurrence; Shock, Septic; Staphylococcal Infections | 1993 |
Serotonin-induced vasodilatation in the human forearm is mediated by the "nitric oxide-pathway": no evidence for involvement of the 5-HT3-receptor.
Topics: Adult; Amino Acid Oxidoreductases; Arginine; Forearm; Free Radical Scavengers; Granisetron; Guanylate Cyclase; Humans; Indazoles; Male; Methylene Blue; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Ondansetron; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Vasodilation | 1993 |
Inhibition of viral replication by interferon-gamma-induced nitric oxide synthase.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Line; Cells, Cultured; Ectromelia virus; Ectromelia, Infectious; Enzyme Induction; Female; Humans; Interferon-gamma; Macrophages; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Simplexvirus; Transfection; Vaccinia virus; Virus Replication | 1993 |
Tumor necrosis factor inhibits stimulated but not basal release of nitric oxide.
Topics: Acetylcholine; Amino Acid Oxidoreductases; Animals; Arginine; Biological Assay; Bradykinin; Cattle; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Luminescent Measurements; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Prostaglandin Endoperoxides, Synthetic; Pulmonary Artery; Tumor Necrosis Factor-alpha | 1993 |
Characterization of endothelial cell amino acid transport systems involved in the actions of nitric oxide synthase inhibitors.
Topics: Amino Acid Oxidoreductases; Amino Acids; Animals; Arginine; Biological Transport; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Leucine; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Swine | 1993 |
NG-methyl-L-arginine functions as an alternate substrate and mechanism-based inhibitor of nitric oxide synthase.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Catalase; Citrulline; Formaldehyde; Hydrogen Peroxide; In Vitro Techniques; Macrophages; Mice; NADP; Nitric Oxide Synthase; omega-N-Methylarginine; Structure-Activity Relationship; Superoxide Dismutase | 1993 |
Effects of NG-substituted arginines on coronary vascular function after endotoxin.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Coronary Vessels; Dogs; Escherichia coli; Female; In Vitro Techniques; Lipopolysaccharides; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Thrombin | 1993 |
Optical difference spectrophotometry as a probe of rat brain nitric oxide synthase heme-substrate interaction.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Brain; Cell Line; Heme; Humans; Kidney; Kinetics; Nitric Oxide Synthase; omega-N-Methylarginine; Protein Binding; Rats; Spectrophotometry; Transfection | 1993 |
Involvement of NK receptors and beta-adrenoceptors in nitric oxide-dependent relaxation of rabbit aorta rings following electrical-field stimulation.
Topics: Adrenergic beta-Antagonists; Animals; Aorta; Arginine; Benzalkonium Compounds; Electric Stimulation; In Vitro Techniques; Male; Morphine; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Phenylephrine; Rabbits; Receptors, Adrenergic, beta; Receptors, Tachykinin; Substance P; Vasodilation | 1993 |
Tetrahydrobiopterin-dependent nitrite oxidation to nitrate in isolated rat hepatocytes.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Biopterins; Cells, Cultured; Cytosol; Humans; Interleukin-1; Kinetics; Lipopolysaccharides; Liver; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1993 |
Role of the nitric oxide synthase pathway in inhibition of growth of interferon-sensitive and interferon-resistant Rickettsia prowazekii strains in L929 cells treated with tumor necrosis factor alpha and gamma interferon.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; In Vitro Techniques; Interferon Type I; Interferon-gamma; L Cells; Mice; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Recombinant Proteins; Rickettsia prowazekii; Tryptophan; Tumor Necrosis Factor-alpha | 1993 |
Nitric oxide and prostacyclin influence coronary vasomotor tone in perfused rabbit heart and modulate endothelin-1 activity.
Topics: Animals; Arginine; Blood Pressure; Coronary Vessels; Endothelins; Epoprostenol; Heart; In Vitro Techniques; Indomethacin; Male; Muscle Relaxation; Muscle Tonus; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Platelet Aggregation Inhibitors; Polydeoxyribonucleotides; Rabbits | 1993 |
Nitric oxide mediates IL-1 beta-induced islet dysfunction and destruction: prevention by dexamethasone.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cyclic GMP; Dexamethasone; Guanidines; Insulin; Insulin Secretion; Interleukin-1; Islets of Langerhans; Male; NADPH Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley | 1993 |
Evidence for the role of nitric oxide in kappa-opiate tolerance in mice.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Amino Acid Oxidoreductases; Analgesics; Animals; Arginine; Drug Tolerance; Male; Mice; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Pyrrolidines; Receptors, Opioid, kappa | 1993 |
Inhibition of nitric oxide synthase delays healing of chronic gastric ulcers.
Topics: Acetates; Acetic Acid; Amino Acid Oxidoreductases; Animals; Arginine; Gastric Mucosa; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroglycerin; omega-N-Methylarginine; Rats; Rats, Wistar; Regional Blood Flow; Stomach; Stomach Ulcer | 1993 |
Reversible inactivation of endothelial nitric oxide synthase by NG-nitro-L-arginine.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Line; Endothelium, Vascular; Kinetics; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Swine | 1993 |
Inhibitors of nitric oxide synthase attenuate human neutrophil chemotaxis in vitro.
Topics: Amino Acid Oxidoreductases; Arginine; Canavanine; Chemotaxis, Leukocyte; Complement C5a, des-Arginine; Cyclic GMP; Humans; In Vitro Techniques; Kinetics; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Stereoisomerism | 1993 |
The nitric oxide synthase inhibitor, N-monomethyl-L-arginine blocks induction of a long-term potentiation-like phenomenon in rat medial frontal cortical neurons in vitro.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Frontal Lobe; In Vitro Techniques; Long-Term Potentiation; Membrane Potentials; Neurons; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley | 1993 |
Endogenous nitric oxide blocks calcium influx induced by glutamate in neurons containing NADPH diaphorase.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Calcium; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Antagonists; Fluorescence; Glutamates; Glutamic Acid; NADPH Dehydrogenase; Neurons; Neurotransmitter Agents; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats | 1993 |
Factors regulating natural transmission of Plasmodium berghei to the mosquito vector, and the cloning of a transmission-blocking immunogen.
Topics: Amino Acid Oxidoreductases; Amino Acid Sequence; Animals; Anopheles; Antigens, Protozoan; Arginine; Base Sequence; Cloning, Molecular; Consensus Sequence; DNA, Complementary; DNA, Protozoan; Female; Host-Parasite Interactions; Insect Vectors; Lipopolysaccharides; Malaria; Male; Mice; Mice, Inbred BALB C; Mice, SCID; Molecular Sequence Data; Nitric Oxide Synthase; omega-N-Methylarginine; Open Reading Frames; Plasmodium; Plasmodium berghei; Protozoan Proteins; Reproduction; Severe Combined Immunodeficiency; Species Specificity | 1993 |
Role of nitric oxide in the control of luteinizing hormone-releasing hormone release in vivo and in vitro.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cerebral Ventricles; Gonadotropin-Releasing Hormone; Hypothalamus, Middle; Injections, Intraventricular; Interneurons; Kinetics; Luteinizing Hormone; Male; Microinjections; Models, Neurological; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Norepinephrine; omega-N-Methylarginine; Orchiectomy; Rats; Rats, Sprague-Dawley; Time Factors | 1993 |
Inhibition of the production of nitric oxide and vasodilator prostaglandins attenuates the cardiovascular response to bacterial endotoxin in adrenalectomized rats.
Topics: Adrenalectomy; Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Calcium; Dexamethasone; Escherichia coli; Glucocorticoids; Indomethacin; Lipopolysaccharides; Male; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; omega-N-Methylarginine; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Shock, Septic; Time Factors | 1993 |
Modulation of neuroeffector transmission by endogenous nitric oxide: a role for acetylcholine receptor-activated nitric oxide formation, as indicated by measurements of nitric oxide/nitrite release.
Topics: Acetylcholine; Amino Acid Oxidoreductases; Animals; Arginine; Atropine; Electric Stimulation; Female; Guinea Pigs; Ileum; Iris; Luminescent Measurements; Male; Muscle Contraction; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Rabbits; Receptors, Cholinergic; Substance P; Synaptic Transmission | 1993 |
Role of nitric oxide in regulation of cerebral microvascular tone and autoregulation of cerebral blood flow in cats.
Topics: Animals; Arginine; Blood Flow Velocity; Blood Pressure; Blood Volume; Cats; Cerebral Arteries; Cerebral Cortex; Cerebrovascular Circulation; Endothelium, Vascular; Female; Homeostasis; Male; Microcirculation; Nitric Oxide; omega-N-Methylarginine | 1994 |
Nitric oxide suppresses IFN-gamma production in the spleen of mercuric chloride-exposed brown Norway rats.
Topics: Animals; Arginine; Cells, Cultured; Erythrocyte Count; Erythrocytes; Female; Interferon-gamma; Lymphocyte Subsets; Mercuric Chloride; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred BN; Rats, Inbred Lew; Spleen | 1995 |
Nitric oxide activity in the human coronary circulation. Impact of risk factors for coronary atherosclerosis.
Topics: Acetylcholine; Adenosine; Adult; Arginine; Arteriosclerosis; Coronary Circulation; Coronary Vessels; Dose-Response Relationship, Drug; Female; Humans; Male; Microcirculation; Middle Aged; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Rest; Risk Factors; Vascular Resistance; Vasodilation | 1995 |
An experimental study of gastric mucosal blood flow in endotoxemia of the rat, with special reference to the vagus nerve and EDRF.
Topics: Acetylcholine; Animals; Arginine; Electric Stimulation; Endothelium, Vascular; Endotoxins; Gastric Mucosa; Gossypol; Laser-Doppler Flowmetry; Lipopolysaccharides; Male; Microscopy, Electron; Nitric Oxide; omega-N-Methylarginine; Rats; Regional Blood Flow; Vagus Nerve | 1995 |
Effects of angiotensin II on isolated rabbit afferent arterioles.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Arterioles; Aspirin; Biphenyl Compounds; Imidazoles; In Vitro Techniques; Indomethacin; Losartan; Lysine; Male; Nitric Oxide; omega-N-Methylarginine; Prostaglandin Antagonists; Prostaglandins; Rabbits; Renal Circulation; Tetrazoles; Vascular Resistance | 1994 |
Ginsenosides of the protopanaxatriol group cause endothelium-dependent relaxation in the rat aorta.
Topics: Animals; Aorta, Thoracic; Arginine; Cyclic GMP; Endothelium, Vascular; Ginsenosides; In Vitro Techniques; Male; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Sapogenins; Saponins; Triterpenes; Vasodilation | 1995 |
Nitric oxide inhibits hypothalamic luteinizing hormone-releasing hormone release by releasing gamma-aminobutyric acid.
Topics: Animals; Arginine; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Hemoglobins; Hypothalamus, Middle; In Vitro Techniques; Male; Models, Neurological; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Potassium; Rats; Rats, Wistar | 1995 |
Differential susceptibility of yeast and hyphal forms of Candida albicans to macrophage-derived nitrogen-containing compounds.
Topics: Animals; Arginine; Candida albicans; Interferon-gamma; Lipopolysaccharides; Macrophages; Mice; Morphogenesis; Nitric Oxide; Nitrogen Compounds; Nitroprusside; omega-N-Methylarginine | 1995 |
Endotoxin-induced desensitization of mouse macrophages is mediated in part by nitric oxide production.
Topics: Animals; Arginine; Cells, Cultured; Desensitization, Immunologic; Dose-Response Relationship, Drug; Endotoxins; Glycolipids; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Nitric Oxide; omega-N-Methylarginine; Time Factors; Tumor Necrosis Factor-alpha | 1995 |
Intracellular killing of Listeria monocytogenes in the J774.1 macrophage-like cell line and the lipopolysaccharide (LPS)-resistant mutant LPS1916 cell line defective in the generation of reactive oxygen intermediates after LPS treatment.
Topics: Animals; Arginine; Cell Division; Cells, Cultured; Drug Interactions; Drug Resistance, Microbial; Hemolysis; Interferon-gamma; Lipopolysaccharides; Listeria monocytogenes; Macrophage Activation; Macrophages; Mice; Mutation; Nitric Oxide; omega-N-Methylarginine; Reactive Oxygen Species; Species Specificity | 1995 |
Role of nitric oxide and melanogenesis in the accomplishment of anticryptococcal activity by the BV-2 microglial cell line.
Topics: Animals; Arginine; Cell Line; Cryptococcus neoformans; Genes, myc; Interferon-gamma; Mice; Microglia; Nitric Oxide; omega-N-Methylarginine; Oncogene Proteins v-raf; Phagocytosis; Protein-Tyrosine Kinases; Recombinant Proteins; Retroviridae; Retroviridae Proteins, Oncogenic; Transfection | 1995 |
Differential hemodynamic effects of L-NMMA in endotoxemic and normal dogs.
Topics: Animals; Arginine; Dogs; Endotoxins; Hemodynamics; Nitric Oxide; omega-N-Methylarginine; Reference Values; Shock, Septic | 1995 |
Nitric oxide up-regulates the release of inflammatory mediators by mouse macrophages.
Topics: Animals; Arginine; Cells, Cultured; Free Radicals; Interleukin-1; Interleukin-6; Luminescent Measurements; Macrophages, Peritoneal; Male; Mice; Mice, Inbred CBA; Nitric Oxide; omega-N-Methylarginine; Tumor Necrosis Factor-alpha; Up-Regulation | 1995 |
Endothelium-derived relaxing factors in the kidney of spontaneously hypertensive rats.
Topics: Acetylcholine; Animals; Arginine; Kidney; Luminescent Measurements; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasodilation | 1995 |
Increased nitric oxide biosynthesis in leukotoxin,9,10-epoxy-12-octadecenoate injured lung.
Topics: Animals; Arginine; Edema; Linoleic Acids; Lung; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Time Factors | 1995 |
Increased nitric oxide synthesis during the development of endotoxin tolerance.
Topics: 6-Ketoprostaglandin F1 alpha; Analysis of Variance; Animals; Arachidonic Acids; Arginine; Cells, Cultured; Drug Tolerance; Endotoxins; Lethal Dose 50; Lipopolysaccharides; Macrophages, Peritoneal; Male; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Rats; Reference Values; Salmonella enteritidis | 1995 |
Nitric oxide dose-response study in the isolated perfused rat kidney after inhibition of endothelium-derived relaxing factor synthesis: the role of serum albumin.
Topics: Animals; Arginine; Diethylamines; Dose-Response Relationship, Drug; In Vitro Techniques; Kidney; Male; Nitric Oxide; Nitroso Compounds; omega-N-Methylarginine; Perfusion; Rats; Rats, Sprague-Dawley; Serum Albumin; Sodium Nitrite; Sulfhydryl Compounds; Vascular Resistance | 1995 |
Renal hemodynamics in acute unilateral ureteral obstruction: contribution of endothelium-derived relaxing factor.
Topics: Acute Disease; Animals; Arginine; Dogs; Female; Hemodynamics; Hyperemia; Kidney; Kidney Diseases; Nitric Oxide; omega-N-Methylarginine; Regional Blood Flow; Ureteral Obstruction | 1995 |
Role of endothelium in hyperpolarization of coronary smooth muscle by adenosine and its analogues.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Arginine; Coronary Vessels; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; In Vitro Techniques; Indomethacin; Membrane Potentials; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Swine; Theophylline; Vasodilator Agents | 1995 |
Possible involvement of nitric oxide in carbachol-induced activation of transglutaminase in rat superior cervical sympathetic ganglia.
Topics: Animals; Arginine; Calcium; Carbachol; Cyclic GMP; Enzyme Activation; Female; Hemoglobins; In Vitro Techniques; Male; Methylene Blue; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Wistar; Superior Cervical Ganglion; Transglutaminases | 1995 |
Effects of intravenous arginine administration on cerebral circulation in the rat.
Topics: Animals; Arginine; Cerebrovascular Circulation; Infusions, Intravenous; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Wistar | 1995 |
Effects of pyridoxalated hemoglobin polyoxyethylene conjugate and other hemoglobin-related substances on arterial blood pressure in anesthetized and conscious rats.
Topics: Adrenergic Antagonists; Anesthesia; Animals; Arginine; Blood Pressure; Cyclooxygenase Inhibitors; Dogs; Dose-Response Relationship, Drug; Female; Guinea Pigs; Heart Rate; Hemoglobins; Injections, Intravenous; Male; Nitric Oxide; omega-N-Methylarginine; Polyethylene Glycols; Rabbits; Rats; Rats, Sprague-Dawley | 1995 |
Role of nitric oxide in immunological liver damage in mice.
Topics: Animals; Arginine; Female; Lipopolysaccharides; Liver; Mice; Monocytes; Mycobacterium bovis; Necrosis; Nitric Oxide; omega-N-Methylarginine; Transaminases | 1995 |
Leukotrienes stimulate pepsinogen secretion from guinea pig gastric chief cells by a nitric oxide-dependent pathway.
Topics: Animals; Arginine; Calcium; Cyclic GMP; Gastric Mucosa; Guinea Pigs; Inositol 1,4,5-Trisphosphate; L-Lactate Dehydrogenase; Leukotrienes; Male; Nitric Oxide; omega-N-Methylarginine; Pepsinogens | 1995 |
Influence of the vascular endothelium on angiotensin II-induced contractions in rabbit renal artery.
Topics: Angiotensin II; Animals; Arginine; Endothelium, Vascular; Indomethacin; Male; Methylene Blue; omega-N-Methylarginine; Phenylephrine; Rabbits; Renal Artery; Vasoconstriction | 1995 |
The role of nitric oxide in endotoxin-elicited hypodynamic circulatory failure.
Topics: Animals; Arginine; Blood Pressure; Cardiac Output; Endotoxins; Hemodynamics; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Shock, Septic; Vascular Resistance; Vasoconstriction | 1994 |
Immunosuppression induced by Salmonella infection is correlated with augmentation of interleukin-2 receptor alpha chain expression in murine splenic lymphocytes.
Topics: Animals; Antibodies, Monoclonal; Arginine; Dose-Response Relationship, Immunologic; Flow Cytometry; Immune Tolerance; Interferon-gamma; Interleukin-4; Lymphocyte Activation; Lymphocytes; Male; Mice; Mice, Inbred BALB C; omega-N-Methylarginine; Receptors, Interleukin-2; Salmonella Infections; Salmonella typhimurium; Spleen; T-Lymphocytes; Time Factors | 1995 |
Effects of portal hypertension on responsiveness of rat mesenteric artery and aorta.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Aorta; Arginine; Blood Pressure; Decerebrate State; Endothelium, Vascular; Hypertension, Portal; Male; Mesenteric Arteries; Microspheres; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; omega-N-Methylarginine; Portal Vein; Potassium Chloride; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Wistar; Thromboxane A2; Vasoconstrictor Agents | 1995 |
The role of nitric oxide in lipoxin A4-induced polymorphonuclear neutrophil-dependent cytotoxicity to human vascular endothelium in vitro.
Topics: Arginine; Cell Communication; Cell Death; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Hydroxyeicosatetraenoic Acids; Lipoxins; Neutrophil Activation; Neutrophils; Nitric Oxide; omega-N-Methylarginine; Superoxides; Tetradecanoylphorbol Acetate; Umbilical Veins | 1995 |
L-arginine depletion by arginase reduces nitric oxide production in endotoxic shock: an electron paramagnetic resonance study.
Topics: Animals; Arginase; Arginine; Ditiocarb; Electron Spin Resonance Spectroscopy; Ferrous Compounds; Kidney; Lipopolysaccharides; Liver; Lung; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Lew; Shock, Septic; Spleen | 1995 |
Relationship between granulocyte macrophage-colony stimulating factor, tumour necrosis factor-alpha and Trypanosoma cruzi infection of murine macrophages.
Topics: Animals; Arginine; Cell Line, Transformed; Cells, Cultured; Granulocyte-Macrophage Colony-Stimulating Factor; Hydrogen Peroxide; Interferon-gamma; Macrophage Activation; Macrophages, Peritoneal; Male; Mice; Mice, Inbred BALB C; Nitric Oxide; Nitrites; omega-N-Methylarginine; Rats; Rats, Inbred F344; Recombinant Proteins; Trypanosoma cruzi; Tumor Necrosis Factor-alpha; Up-Regulation | 1995 |
Simultaneous generation of nitric oxide and superoxide by inflammatory cells in rats.
Topics: Animals; Arginine; Carrageenan; Cell Survival; Granuloma; In Vitro Techniques; Inflammation; Kinetics; Leukocytes; Male; Nitric Oxide; omega-N-Methylarginine; Ornithine; Rats; Rats, Sprague-Dawley; Superoxides; Time Factors; Zymosan | 1995 |
Comparison of the hemodynamic effects of urapidil and flesinoxan in healthy volunteers.
Topics: Adult; Antihypertensive Agents; Arginine; Dose-Response Relationship, Drug; Doxazosin; Hemodynamics; Humans; Male; Methoxamine; omega-N-Methylarginine; Piperazines; Regional Blood Flow; Serotonin; Vascular Resistance | 1994 |
The effects of administration of nitric oxide inhibitors during small bowel preservation and reperfusion.
Topics: Animals; Arginine; Blood Urea Nitrogen; Glutaminase; Graft Survival; Intestinal Mucosa; Intestine, Small; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; omega-N-Methylarginine; Organ Preservation; Rats; Rats, Inbred Lew; Reperfusion; Reperfusion Injury; Transplantation, Heterotopic | 1994 |
Enhancement of endothelium-dependent contraction of the canine coronary artery by UW solution.
Topics: Acetylcholine; Adenosine; Allopurinol; Animals; Arginine; Cell Communication; Coronary Vessels; Dinoprost; Dogs; Endothelium, Vascular; Female; Glutathione; Hypoxia; Insulin; Isoproterenol; Male; Nitric Oxide; omega-N-Methylarginine; Organ Preservation; Organ Preservation Solutions; Potassium; Raffinose; Time Factors; Vasoconstriction; Vasodilation | 1994 |
Effects of endothelium-derived nitric oxide on skin and digital blood flow in humans.
Topics: Adult; Arginine; Blood Flow Velocity; Endothelium, Vascular; Female; Fingers; Humans; Laser-Doppler Flowmetry; Male; Nitric Oxide; omega-N-Methylarginine; Plethysmography; Skin; Vasoconstriction | 1994 |
LPC in oxidized LDL elicits vasocontraction and inhibits endothelium- dependent relaxation.
Topics: Animals; Arginine; Copper; Coronary Vessels; Dinoprost; Endothelium, Vascular; Humans; Indomethacin; Lipoproteins, LDL; Lysophosphatidylcholines; Male; Nitroglycerin; omega-N-Methylarginine; Oxidation-Reduction; Superoxide Dismutase; Swine; Thrombin; Vasoconstriction; Vasodilation | 1994 |
NG-monomethyl-L-arginine inhibits Arbacia fertilization and differentiation.
Topics: Animals; Arginine; Cell Differentiation; Female; Fertilization; Hydrogen Peroxide; omega-N-Methylarginine; Ovum; Sea Urchins | 1994 |
Endothelium-dependent, nitric oxide-mediated inhibition of angiotensin II-induced contractions in rabbit aorta.
Topics: Acetylcholine; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta; Arginine; Dose-Response Relationship, Drug; Endothelium, Vascular; Imidazoles; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Pyridines; Rabbits | 1994 |
Cyclophosphamide uncovers two separate macrophage subpopulations with opposite immunogenic potential and different patterns of monokine production.
Topics: Animals; Arginine; Cell Division; Cell Line; Cells, Cultured; Cyclophosphamide; Cytokines; Dinoprostone; Hybridomas; Interleukin-6; L Cells; Lipopolysaccharides; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Monokines; Nitrites; omega-N-Methylarginine; Tumor Necrosis Factor-alpha | 1994 |
Selective loss of microvascular endothelial function.
Topics: Arginine; Endothelium, Vascular; Humans; Hypercholesterolemia; Microcirculation; Nitric Oxide; omega-N-Methylarginine; Vasodilation | 1995 |
Inhalation exposure to isobutyl nitrite inhibits macrophage tumoricidal activity and modulates inducible nitric oxide.
Topics: Administration, Inhalation; Animals; Arginine; Cell Adhesion; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Cytotoxicity, Immunologic; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Female; Interferon-gamma; Killer Cells, Natural; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitrites; omega-N-Methylarginine; Sarcoma, Kaposi; Tumor Necrosis Factor-alpha; Vasodilator Agents | 1995 |
Ligation of CD23 activates soluble guanylate cyclase in human monocytes via an L-arginine-dependent mechanism.
Topics: Antibodies, Monoclonal; Antigen-Antibody Complex; Arginine; Cells, Cultured; Cyclic AMP; Cyclic GMP; Enzyme Activation; Guanylate Cyclase; Humans; Immunoglobulin E; Interleukin-4; Monocytes; Nitric Oxide; omega-N-Methylarginine; Receptors, IgE | 1995 |
Dilatation of cerebral microvessels mediated by endothelin ETB receptor and nitric oxide in cats.
Topics: Animals; Arginine; Blood Pressure; Blood Volume; Brain; Capillaries; Carotid Arteries; Cats; Dose-Response Relationship, Drug; Endothelins; Injections, Intra-Arterial; Nitric Oxide; omega-N-Methylarginine; Peptide Fragments; Receptors, Endothelin; Vasodilation | 1994 |
Potentiation of nitric oxide-mediated vascular relaxation by SC52608, a superoxide dismutase mimic.
Topics: Animals; Antioxidants; Aorta, Thoracic; Arginine; Blood Pressure; Chlorides; Cyclic GMP; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Male; Manganese Compounds; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Organometallic Compounds; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Vasodilation | 1995 |
Identification of a specific transport system for L-arginine in human platelets.
Topics: Arginine; Biological Transport; Blood Platelets; Carrier Proteins; Humans; Kinetics; Lysine; Nitric Oxide; omega-N-Methylarginine; Ornithine; Sodium | 1995 |
Fibronectin activates murine peritoneal macrophages for tumor cell destruction in the presence of IFN-gamma.
Topics: Animals; Arginine; Cytotoxicity, Immunologic; Fibronectins; Interferon-gamma; Lipopolysaccharides; Macrophage Activation; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Nitric Oxide; omega-N-Methylarginine; Recombinant Proteins; Sarcoma, Experimental; Tumor Necrosis Factor-alpha | 1995 |
The action of amyl nitrite and isosorbide dinitrate on the contractility of sphincter of Oddi of guinea-pigs.
Topics: Acetylcholine; Amyl Nitrite; Animals; Arginine; Female; Guinea Pigs; In Vitro Techniques; Isosorbide Dinitrate; Male; Methylene Blue; Muscle Contraction; Nitric Oxide; omega-N-Methylarginine; Potassium Chloride; Sphincter of Oddi | 1994 |
Cerebral vasodilatory effect of high-dose, intravascular endothelin-1: inhibition by NG-monomethyl-L-arginine.
Topics: Animals; Arginine; Blood Pressure; Blood Volume; Carotid Arteries; Cats; Cerebrovascular Circulation; Endothelin Receptor Antagonists; Endothelins; Injections, Intra-Arterial; Microcirculation; omega-N-Methylarginine; Peptides, Cyclic; Vasodilation | 1994 |
Vasopressin mediated vasodilation of cerebral arteries.
Topics: Anesthesia; Animals; Arginine; Blood Pressure; Cerebral Angiography; Cerebral Arteries; Circle of Willis; Dogs; Injections, Intra-Arterial; Nitric Oxide; omega-N-Methylarginine; Vasodilation; Vasopressins; Vertebral Artery | 1994 |
Effects of vasopressin on regional cerebral blood flow in dogs.
Topics: Animals; Arginine; Blood Volume; Cerebrovascular Circulation; Cisterna Magna; Dogs; Injections; omega-N-Methylarginine; Parietal Lobe; Regional Blood Flow; Vasopressins | 1994 |
A role of nitric oxide in vasomotor control of cerebral parenchymal arterioles in rats.
Topics: Animals; Arginine; Arginine Vasopressin; Arterioles; Cerebrovascular Circulation; In Vitro Techniques; Male; Muscle Tonus; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Oxyhemoglobins; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 1994 |
Dysfunction of nitric oxide in the spastic basilar arteries after subarachnoid hemorrhage.
Topics: Animals; Arginine; Basilar Artery; Blood Pressure; Cerebral Angiography; Cisterna Magna; Dogs; Injections; Ischemic Attack, Transient; Nitric Oxide; omega-N-Methylarginine; Subarachnoid Hemorrhage; Superoxide Dismutase; Vasodilation; Vasopressins | 1994 |
Nitric oxide mediates immunologic injury to kidney mesangium in experimental glomerulonephritis.
Topics: Animals; Antilymphocyte Serum; Arginine; Culture Techniques; Glomerular Mesangium; Glomerulonephritis; Macrophages; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta | 1995 |
N-methyl-D-aspartate-induced excessive formation of nitric oxide in CHP100 neuroblastoma cells produces death of BMEL melanoma cells in co-culture.
Topics: Arginine; Cell Death; Dizocilpine Maleate; Histocytochemistry; Humans; Melanoma, Experimental; N-Methylaspartate; NADPH Dehydrogenase; Neuroblastoma; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Tumor Cells, Cultured | 1994 |
Role of the endothelium in regulation of vascular functions in two teleosts.
Topics: Acetylcholine; Animals; Aorta; Arginine; Endothelins; Endothelium, Vascular; Epinephrine; Fishes; In Vitro Techniques; Indomethacin; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Potassium; Salmon; Species Specificity; Vasoconstriction; Vasodilation | 1994 |
Nitric oxide causes hyporeactivity to phenylephrine in isolated perfused livers from endotoxin-treated rats.
Topics: Animals; Arginine; Blood Pressure; Endotoxins; Escherichia coli; Glucose; In Vitro Techniques; Liver; Male; Nitric Oxide; omega-N-Methylarginine; Penicillamine; Perfusion; Phenylephrine; Portal System; Rats; Rats, Sprague-Dawley; Regional Blood Flow; S-Nitroso-N-Acetylpenicillamine; Tromethamine; Vasoconstriction; Vasodilator Agents | 1995 |
Leukotoxin, 9,10-epoxy-12-octadecenoate causes pulmonary vasodilation in rats.
Topics: Animals; Arginine; Endothelins; Exotoxins; In Vitro Techniques; Linoleic Acids; Male; Methylene Blue; omega-N-Methylarginine; Perfusion; Potassium Chloride; Pulmonary Artery; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Vasodilation | 1995 |
Targets of nitric oxide in a mouse model of liver inflammation by Corynebacterium parvum.
Topics: Animals; Arginine; Blood; Blotting, Western; Disease Models, Animal; Electron Spin Resonance Spectroscopy; Heme; Hemoglobins; Inflammation; Liver; Liver Diseases; Male; Mice; Nitric Oxide; omega-N-Methylarginine; Propionibacterium acnes | 1995 |
Inhibition by lithium of cyclic GMP formation without inhibition of nitric oxide generation in the mouse neuroblastoma cell (N1E-115).
Topics: Animals; Arginine; Brain Neoplasms; Carbachol; Cyclic GMP; Guanylate Cyclase; Lithium; Mice; Muscarinic Antagonists; Neuroblastoma; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Tumor Cells, Cultured | 1994 |
Nitric oxide modulates rhythmic slow activity in rat hippocampal slices.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Arginine; Carbachol; Cyclic GMP; Electrophysiology; Hemoglobins; Hippocampus; In Vitro Techniques; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley | 1994 |
Role of nitric oxide in the peripheral vessels of patients with familial amyloidotic polyneuropathy (FAP) type I.
Topics: Adult; Amyloidosis; Arginine; Blood Vessels; Body Temperature; Female; Humans; Leg; Male; Middle Aged; Muscles; Nitrates; Nitric Oxide; Nitrites; omega-N-Methylarginine; Peripheral Nervous System Diseases; Regional Blood Flow | 1994 |
Human astrocytes inhibit intracellular multiplication of Toxoplasma gondii by a nitric oxide-mediated mechanism.
Topics: Animals; Arginine; Astrocytes; Cells, Cultured; Humans; Nitric Oxide; omega-N-Methylarginine; Toxoplasma | 1995 |
Nitric oxide production and heart failure.
Topics: Arginine; Heart Failure; Humans; Nitrates; Nitric Oxide; omega-N-Methylarginine; Vascular Resistance; Vasoconstriction | 1995 |
Generation of nitric oxide inhibits formation of superoxide in macrophages during activation.
Topics: Adenosine Diphosphate; Animals; Arginine; Cells, Cultured; Cytoplasm; Electrophoresis, Polyacrylamide Gel; Interferon-gamma; Lipopolysaccharides; Luminescent Measurements; Macrophage Activation; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Molecular Weight; Mycobacterium bovis; Nitric Oxide; Nitrites; Nitroprusside; omega-N-Methylarginine; Recombinant Proteins; Superoxides; Tetradecanoylphorbol Acetate | 1994 |
Interleukin-2 (IL-2) induces corticotropin-releasing factor (CRF) release from the amygdala and involves a nitric oxide-mediated signaling; comparison with the hypothalamic response.
Topics: Acetylcholine; Adrenocorticotropic Hormone; Amygdala; Animals; Arginine; Corticosterone; Corticotropin-Releasing Hormone; Hypothalamus; Interleukin-2; Male; Nitric Oxide; Nitroprusside; Norepinephrine; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley | 1995 |
Regulatory role of nitric oxide in the IL-4-induced IgE production by normal human peripheral blood mononuclear cells.
Topics: Arginine; Humans; Immunoglobulin E; In Vitro Techniques; Interleukin-4; Leukocytes, Mononuclear; Molsidomine; Nitric Oxide; Nitrites; omega-N-Methylarginine; Oxidants; Receptors, IgE | 1994 |
Decreased macrophage-mediated cytotoxicity in mammary-tumor-bearing mice is related to alteration of nitric-oxide production and/or release.
Topics: Animals; Arginine; Cytotoxicity, Immunologic; Endotoxins; Hydrogen Peroxide; Immunoglobulin Fab Fragments; Interferon-gamma; Lipopolysaccharides; Macrophages, Peritoneal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Nitric Oxide; omega-N-Methylarginine; Receptors, Cell Surface; Tumor Necrosis Factor-alpha | 1995 |
Modulation of glutamate and aspartate release from slices of hippocampal area CA1 by inhibitors of arachidonic acid metabolism.
Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arginine; Aspartic Acid; Female; Flavanones; Flavonoids; gamma-Aminobutyric Acid; Glutamates; Hippocampus; In Vitro Techniques; Indoles; Indomethacin; Masoprocol; omega-N-Methylarginine; Platelet Activating Factor; Potassium; Prostaglandin-Endoperoxide Synthases; Quinacrine; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Taurine | 1995 |
Forearm blood flow response to NO synthase inhibitor in essential hypertension.
Topics: Animals; Arginine; Forearm; Humans; Hypertension; Nitric Oxide; omega-N-Methylarginine | 1994 |
Nitric oxide is responsible for flow-dependent dilatation of human peripheral conduit arteries in vivo.
Topics: Adult; Arginine; Aspirin; Blood Pressure; Epoprostenol; Female; Forearm; Heart Rate; Humans; Hyperemia; Male; Nitric Oxide; omega-N-Methylarginine; Radial Artery; Regional Blood Flow; Ultrasonography, Doppler; Vasodilation | 1995 |
Roles of gamma interferon and other cytokines in suppression of the spleen cell proliferative response to concanavalin A and toxoplasma antigen during acute toxoplasmosis.
Topics: Acute Disease; Animals; Antibodies, Monoclonal; Antigens, Protozoan; Arginine; Cell Division; Cells, Cultured; Concanavalin A; Cytokines; Female; Immune Tolerance; Interferon-gamma; Interleukin-10; Lymphocytes; Mice; Mice, Inbred CBA; Nitric Oxide; Nitrites; omega-N-Methylarginine; Spleen; Toxoplasmosis, Animal | 1995 |
Atrial natriuretic peptide inhibits nitric oxide synthesis in mouse macrophages.
Topics: Animals; Arginine; Atrial Natriuretic Factor; Cells, Cultured; Female; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred BALB C; Nitric Oxide; omega-N-Methylarginine; Rats | 1995 |
Evidence to suggest nitric oxide is an interstitial regulator of Leydig cell steroidogenesis.
Topics: Animals; Arginine; Cells, Cultured; Chorionic Gonadotropin; Cyclic GMP; Leydig Cells; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Testosterone | 1995 |
Acute normovolaemic anaemia prevents ethanol-induced gastric damage in rats through a blood flow related mechanism.
Topics: Anemia; Animals; Arginine; Blood Flow Velocity; Ethanol; Gastric Mucosa; Gastrointestinal Diseases; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Vasopressins | 1994 |
Reduction in human neutrophil superoxide anion generation by n-3 polyunsaturated fatty acids: role of cyclooxygenase products and endothelium-derived relaxing factor.
Topics: Arachidonic Acid; Arginine; Aspirin; Depression, Chemical; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids, Omega-3; Humans; Indomethacin; Neutrophils; Nitric Oxide; omega-N-Methylarginine; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Respiratory Burst; Superoxides | 1994 |
Arginine-dependent generation of reactive nitrogen intermediates is instrumental in the in vitro killing of protoscoleces of Echinococcus multilocularis by activated macrophages.
Topics: Animals; Arginine; Cytotoxicity, Immunologic; Echinococcus; Female; Interferon-gamma; Larva; Lipopolysaccharides; Macrophage Activation; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Nitric Oxide; omega-N-Methylarginine; Reactive Oxygen Species; Superoxide Dismutase | 1993 |
Trypanosoma cruzi upregulates nitric oxide release by IFN-gamma-preactivated macrophages, limiting cell infection independently of the respiratory burst.
Topics: Animals; Arginine; Catalase; Cells, Cultured; Interferon-gamma; Macrophage Activation; Macrophages, Peritoneal; Male; Mice; Mice, Inbred BALB C; Nitric Oxide; omega-N-Methylarginine; Recombinant Proteins; Respiratory Burst; Superoxide Dismutase; Trypanosoma cruzi; Up-Regulation | 1993 |
Administration of NG-monomethyl-L-arginine in a marginal renal subcapsular mouse islet transplant model.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Drug Administration Schedule; Infusions, Parenteral; Injections, Intraperitoneal; Islets of Langerhans Transplantation; Mice; Mice, Inbred C57BL; Nitric Oxide; omega-N-Methylarginine; Transplantation, Heterotopic; Transplantation, Isogeneic | 1995 |
S14080, a peripheral analgesic acting by release of an endogenous circulating opioid-like substance.
Topics: Adrenalectomy; Analgesics; Animals; Arginine; Dipyrone; Drug Tolerance; Edema; Endorphins; Fever; Hyperalgesia; Indomethacin; Male; Methylene Blue; Nitric Oxide; omega-N-Methylarginine; Pain Measurement; Rats; Rats, Wistar; Thiazoles; Yohimbine | 1995 |
Nitric oxide mediates activity-dependent synaptic suppression at developing neuromuscular synapses.
Topics: Action Potentials; Animals; Arginine; Cells, Cultured; Cyclic GMP; Hemoglobins; Neuromuscular Junction; Neuronal Plasticity; Nitric Oxide; omega-N-Methylarginine; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Synapses; Xenopus | 1995 |
Pharmacological reactivity of human epicardial coronary arteries: characterization of relaxation responses to endothelium-derived relaxing factor.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adult; Aged; Arginine; Coronary Vessels; Female; Humans; In Vitro Techniques; Indomethacin; Male; Middle Aged; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Prostaglandin Endoperoxides, Synthetic; Thromboxane A2; Vasoconstrictor Agents | 1994 |
Evidence for reduction of bradykinin-induced bronchoconstriction in guinea-pigs by release of nitric oxide.
Topics: Aerosols; Animals; Arginine; Blood Pressure; Bradykinin; Bronchoconstriction; Capillary Permeability; Capsaicin; Guinea Pigs; Hemodynamics; In Vitro Techniques; Injections, Intravenous; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Pulmonary Circulation; Vagotomy; Vascular Resistance | 1994 |
Modulation of morphine antinociception in the mouse by endogenous nitric oxide.
Topics: Acetates; Acetic Acid; Analgesics; Animals; Arginine; Hot Temperature; Male; Mice; Morphine; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Pain Measurement; Psychomotor Performance; Reaction Time | 1994 |
Loss and degradation of enzyme-bound heme induced by cellular nitric oxide synthesis.
Topics: Arginine; Catalase; Cells, Cultured; Cytochrome P-450 Enzyme System; Cytokines; Heme; Iron; Liver; Microsomes, Liver; Nitric Oxide; omega-N-Methylarginine; Penicillamine; RNA, Messenger; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents | 1995 |
Nitric oxide release is present from incubated skeletal muscle preparations.
Topics: Animals; Arginine; Biological Transport; Deoxyglucose; Electric Stimulation; Male; Muscle, Skeletal; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley | 1994 |
Inhibition of T-cell proliferation induced by a cell-free Salmonella typhimurium extract does not involve a nitric oxide-mediated mechanism.
Topics: Animals; Arginine; Cell-Free System; Cells, Cultured; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Nitric Oxide; omega-N-Methylarginine; Receptors, Interleukin-2; Salmonella typhimurium; T-Lymphocytes | 1994 |
Monocyte chemoattractant protein 1 inhibits growth of rat vascular smooth muscle cells.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arginine; Arteriosclerosis; Cell Division; Cells, Cultured; Chemokine CCL2; Chemotactic Factors; Cyclic AMP; Cyclic GMP; DNA; Gene Expression; Humans; Indomethacin; Lipopolysaccharides; Muscle, Smooth, Vascular; omega-N-Methylarginine; Rats; Recombinant Proteins; Thymidine | 1995 |
Inducible L-arginine/nitric oxide pathway in human internal mammary artery and saphenous vein.
Topics: Aged; Arginine; Endothelium, Vascular; Female; Humans; In Vitro Techniques; Indomethacin; Interleukin-1; Lipopolysaccharides; Male; Mammary Arteries; Middle Aged; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Phenylephrine; Potassium Chloride; Saphenous Vein; Vasoconstriction | 1995 |
Vasorelaxant mechanism of the new vasodilator, FK409.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Arginine; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Guanylate Cyclase; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitro Compounds; Nitroglycerin; omega-N-Methylarginine; Oxyhemoglobins; Rabbits; Rats; Rats, Sprague-Dawley; Solubility; Vasodilator Agents | 1993 |
Inhibition of nitric oxide synthesis.
Topics: Arginine; Blood Pressure; Coronary Circulation; Heart Rate; Hemodynamics; Humans; Nitric Oxide; omega-N-Methylarginine; Shock, Septic | 1993 |
Bradykinin and capsaicin stimulate cyclic GMP production in cultured rat dorsal root ganglion neurons via a nitrosyl intermediate.
Topics: Animals; Arginine; Bradykinin; Bradykinin Receptor Antagonists; Calcium; Capsaicin; Cells, Cultured; Cyclic GMP; Ganglia, Spinal; Guanylate Cyclase; Methylene Blue; Neurons; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Receptors, Bradykinin | 1993 |
Increased nitric oxide in exhaled air of asthmatic patients.
Topics: Adrenal Cortex Hormones; Adult; Arginine; Asthma; Breath Tests; Female; Humans; Luminescent Measurements; Male; Nitric Oxide; omega-N-Methylarginine; Reproducibility of Results; Respiration; Spirometry | 1994 |
Role of nitric oxide in eicosanoid synthesis and uterine motility in estrogen-treated rat uteri.
Topics: Animals; Arginine; Eicosanoids; Estradiol; Female; Guanylate Cyclase; In Vitro Techniques; Lipoxygenase; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Wistar; Uterine Contraction; Uterus | 1994 |
Growth hormone-releasing factor increases somatostatin release and mRNA levels in the rat periventricular nucleus via nitric oxide by activation of guanylate cyclase.
Topics: Animals; Arginine; Cyclic GMP; Cycloheximide; Dibutyryl Cyclic GMP; Enzyme Activation; Gonadotropin-Releasing Hormone; Guanylate Cyclase; In Vitro Techniques; Male; Models, Biological; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; RNA, Messenger; Somatostatin | 1994 |
Endothelium-mediated and direct actions of acetylcholine on rabbit aortic baroreceptors.
Topics: Acetylcholine; Animals; Antihypertensive Agents; Aorta; Arginine; Atropine; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Hexamethonium; Hexamethonium Compounds; Male; Norepinephrine; omega-N-Methylarginine; Pressoreceptors; Rabbits; Vasoconstriction | 1994 |
Mechanism of diclofenac analgesia: direct blockade of inflammatory sensitization.
Topics: Analgesia; Animals; Arginine; Carrageenan; Diclofenac; Dinoprostone; Drug Interactions; Enzyme Activation; Guanylate Cyclase; Hyperalgesia; Indomethacin; Inflammation; Injections, Intra-Articular; Knee Injuries; Male; Methylene Blue; Nitric Oxide; Nociceptors; omega-N-Methylarginine; Pain Measurement; Rats; Rats, Wistar | 1994 |
Nitric oxide accounts for histamine-induced increases in macromolecular extravasation.
Topics: Aminoquinolines; Animals; Arginine; Capillary Permeability; Cheek; Cricetinae; Drug Synergism; Enzyme Activation; Guanylate Cyclase; Histamine; Macromolecular Substances; Male; Mesocricetus; Nitric Oxide; omega-N-Methylarginine; Venules | 1994 |
An obligatory role for nitric oxide in autonomic control of mammalian heart rate.
Topics: Acetylcholine; Adrenergic beta-Antagonists; Animals; Arginine; Autonomic Nervous System; Biological Clocks; Calcium; Calcium Channels; Carbachol; Heart Rate; In Vitro Techniques; Membrane Potentials; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Parasympatholytics; Rabbits | 1994 |
Enhanced basal nitric oxide production in heart failure: another failed counter-regulatory vasodilator mechanism?
Topics: Aged; Arginine; Cardiac Output, Low; Female; Heart Failure; Heart Function Tests; Hemodynamics; Humans; Male; Middle Aged; Nitric Oxide; omega-N-Methylarginine; Vasodilation | 1994 |
Enhanced basal nitric oxide production in heart failure.
Topics: Arginine; Heart Failure; Hemodynamics; Humans; Nitric Oxide; omega-N-Methylarginine | 1994 |
Consequences of acute nitric oxide synthesis inhibition in experimental glomerulonephritis.
Topics: Animals; Arginine; Disease Models, Animal; Glomerulonephritis; Male; Neutrophils; Nitric Oxide; omega-N-Methylarginine; Proteinuria; Rats; Rats, Wistar; Renal Circulation | 1994 |
Modulation of rat peripheral polymorphonuclear leukocyte response by nitric oxide and arginine.
Topics: Animals; Arachidonic Acid; Arginine; Free Radicals; Hydroxyl Radical; Luminescent Measurements; Luminol; Male; Malondialdehyde; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Peroxidase; Rats; Rats, Sprague-Dawley; Superoxides; Tetradecanoylphorbol Acetate | 1994 |
Perfusion pressure and volume status determine the microvascular response of the rat kidney to NG-monomethyl-L-arginine.
Topics: Animals; Arginine; Arterioles; Blood Pressure; Blood Volume; Capillaries; Hemodynamics; In Vitro Techniques; Kidney; Microcirculation; Microscopy, Video; Nitric Oxide; omega-N-Methylarginine; Perfusion; Rats; Rats, Wistar; Renal Circulation | 1994 |
Nitric oxide and proteoglycan biosynthesis by human articular chondrocytes in alginate culture.
Topics: Adult; Alginates; Arginine; Cartilage, Articular; Cells, Cultured; Culture Techniques; Dose-Response Relationship, Drug; Glucuronic Acid; Hexuronic Acids; Humans; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Kinetics; Middle Aged; Nitric Oxide; omega-N-Methylarginine; Penicillamine; Proteoglycans; Recombinant Proteins; S-Nitroso-N-Acetylpenicillamine; Sialoglycoproteins | 1994 |
Nitric oxide produced by macrophages mediates suppression of ConA-induced proliferative responses of splenic leukocytes in the diabetes-prone BB rat.
Topics: Analysis of Variance; Animals; Arginine; Cells, Cultured; Concanavalin A; Diabetes Mellitus, Type 1; Lymphocyte Activation; Lymphocytes; Macrophages; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred BB; Rats, Inbred Lew; Rats, Inbred WF; Rats, Sprague-Dawley; Rats, Wistar; Species Specificity; Spleen | 1994 |
Tumor necrosis factor-alpha regulates in vivo nitric oxide synthesis and induces liver injury during endotoxemia.
Topics: Animals; Arginine; Endotoxins; Female; Lipopolysaccharides; Liver; Mice; Mice, Inbred BALB C; Nitrates; Nitric Oxide; Nitrites; omega-N-Methylarginine; Ornithine Carbamoyltransferase; Propionibacterium acnes; Tumor Necrosis Factor-alpha | 1994 |
Endogenous nitric oxide attenuates ethanol-induced perturbation of hepatic circulation in the isolated perfused rat liver.
Topics: Analysis of Variance; Animals; Arginine; Ethanol; In Vitro Techniques; L-Lactate Dehydrogenase; Liver; Liver Circulation; Male; Microcirculation; Nitric Oxide; omega-N-Methylarginine; Perfusion; Portal Pressure; Rats; Rats, Sprague-Dawley; Vasoconstriction | 1994 |
Is there a role for nitric oxide in contrast material toxicity?
Topics: Animals; Arginine; Immunization; Immunoglobulin E; Iothalamate Meglumine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Ovalbumin; Rats; Rats, Inbred BN; Rats, Sprague-Dawley; Rats, Wistar | 1994 |
Effect of NG-monomethyl-L-arginine on regional vascular resistance in rats.
Topics: Animals; Arginine; Hemodynamics; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Wistar; Vascular Resistance | 1994 |
Nitric oxide is an important mediator for tumoricidal activity in vivo.
Topics: Animals; Antibodies; Arginine; Cell Line; Cell Survival; Cytokines; Female; Humans; Immunity, Innate; Interferon-gamma; Lipopolysaccharides; Mice; Mice, Inbred C3H; Mice, Nude; Mycobacterium bovis; Nitric Oxide; omega-N-Methylarginine; Ovarian Neoplasms; Teratocarcinoma; Transplantation, Heterologous; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1994 |
Interleukin 12 induction of interferon gamma-dependent protection against malaria.
Topics: Animals; Antibodies, Monoclonal; Arginine; B-Lymphocytes; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Female; Interferon-gamma; Interleukin-12; Killer Cells, Natural; Lymphocyte Depletion; Malaria; Mice; Mice, Inbred BALB C; Mice, SCID; Nitric Oxide; omega-N-Methylarginine; Plasmodium yoelii; Rats; Recombinant Proteins; T-Lymphocytes | 1994 |
Tumor necrosis factor-alpha decreases pulmonary artery endothelial nitrovasodilator via protein kinase C.
Topics: Animals; Arginine; Calcimycin; Cattle; Endothelium, Vascular; Nitrites; Nitro Compounds; Nitroso Compounds; omega-N-Methylarginine; Peroxides; Protein Kinase C; Pulmonary Artery; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Vasodilator Agents | 1994 |
Acute endothelial reperfusion injury after coronary artery bypass grafting.
Topics: Acute Disease; Animals; Arginine; Cell Hypoxia; Coronary Artery Bypass; Coronary Vessels; Dinoprost; Dogs; Endothelium, Vascular; Female; Male; Microscopy, Electron, Scanning; Microscopy, Electron, Scanning Transmission; Models, Biological; Muscle, Smooth, Vascular; Myocardial Contraction; Myocardial Revascularization; Nitric Oxide; omega-N-Methylarginine; Platelet Adhesiveness; Platelet Aggregation; Reperfusion Injury | 1994 |
Estrogen augments the contribution of nitric oxide to blood pressure regulation in transgenic hypertensive rats expressing the mouse Ren-2 gene.
Topics: Animals; Animals, Genetically Modified; Arginine; Blood Pressure; Estrogens; Female; Gene Expression; Hemodynamics; Hypertension; Mice; Nitric Oxide; omega-N-Methylarginine; Ovariectomy; Rats; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System | 1994 |
Involvement of Fc epsilon RII/CD23 and L-arginine-dependent pathway in IgE-mediated stimulation of human monocyte functions.
Topics: Arginine; Cells, Cultured; Cytokines; Humans; Immunoglobulin E; Molsidomine; Monocytes; Nitric Oxide; omega-N-Methylarginine; Receptors, IgE; Signal Transduction; Superoxides; Thromboxane B2 | 1994 |
Role of nitric oxide in reactive hyperemia in human forearm vessels.
Topics: Adult; Arginine; Forearm; Humans; Hyperemia; Male; Nitric Oxide; omega-N-Methylarginine; Regional Blood Flow; Vasodilation | 1994 |
NG-methyl-L-arginine, an inhibitor of nitric oxide formation, acts synergistically with dobutamine to improve cardiovascular performance in endotoxemic dogs.
Topics: Animals; Arginine; Cardiovascular System; Dobutamine; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Synergism; Drug Therapy, Combination; Male; Nitric Oxide; omega-N-Methylarginine; Prospective Studies; Random Allocation; Shock, Septic; Time Factors | 1994 |
A nitric oxide synthase inhibitor reduces inflammation, down-regulates inflammatory cytokines and enhances interleukin-10 production in carrageenin-induced oedema in mice.
Topics: Animals; Arginine; Carrageenan; Down-Regulation; Drug Hypersensitivity; Edema; Female; Hypersensitivity, Delayed; Inflammation; Interferon-gamma; Interleukin-10; Interleukins; Mice; Mice, Inbred BALB C; Nitric Oxide; omega-N-Methylarginine | 1994 |
Nitrite production by macrophages derived from BCG-resistant and -susceptible congenic mouse strains in response to IFN-gamma and infection with BCG.
Topics: Animals; Arginine; Base Sequence; Blotting, Northern; Cell Line; Disease Susceptibility; Female; Interferon-gamma; Macrophages; Male; Mice; Mice, Inbred Strains; Molecular Sequence Data; Mycobacterium bovis; Nitric Oxide; Nitrogen Oxides; omega-N-Methylarginine; Recombinant Proteins; Species Specificity; Tuberculosis | 1994 |
Difference in Legionella pneumophila growth permissiveness between J774.1 murine macrophage-like JA-4 cells and lipopolysaccharide (LPS)-resistant mutant cells, LPS1916, after stimulation with LPS.
Topics: Animals; Arginine; Cell Line; Dose-Response Relationship, Drug; Interferon-gamma; Iron; Legionella pneumophila; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Mutation; omega-N-Methylarginine; Receptors, Transferrin; Respiratory Burst | 1994 |
Human pancreatic islet beta-cell destruction by cytokines is independent of nitric oxide production.
Topics: Arginine; Cell Survival; Cells, Cultured; Cytokines; DNA; Humans; Insulin; Interferon-gamma; Interleukin-1; Islets of Langerhans; Nitric Oxide; omega-N-Methylarginine; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1994 |
Macrophages in mice acutely infected with lymphocytic choriomeningitis virus are primed for nitric oxide synthesis.
Topics: Animals; Arginine; Cell Division; Cells, Cultured; Concanavalin A; Female; Immune Tolerance; Interferon-gamma; Interleukin-2; Lipopolysaccharides; Lymphocytic Choriomeningitis; Lymphocytic choriomeningitis virus; Macrophage Activation; Macrophages; Mice; Mice, Inbred BALB C; Nitric Oxide; omega-N-Methylarginine; Spleen; T-Lymphocytes | 1994 |
Human monocytes cultured with and without interferon-gamma inhibit Plasmodium falciparum parasite growth in vitro via secretion of reactive nitrogen intermediates.
Topics: Animals; Arginine; Cells, Cultured; Humans; Interferon-gamma; Monocytes; Nitric Oxide; omega-N-Methylarginine; Plasmodium falciparum; Recombinant Proteins | 1994 |
Nitric oxide regulates cerebral arteriolar tone in rats.
Topics: Animals; Arginine; Arterioles; Cerebrovascular Circulation; Indomethacin; Male; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Perfusion; Rats; Rats, Sprague-Dawley; Vasomotor System | 1994 |
Effects of endothelin, calcium channel blockade and EDRF inhibition on the contractility of human uteroplacental arteries.
Topics: Adult; Arginine; Arteries; Calcium Channel Blockers; Dose-Response Relationship, Drug; Endothelins; Female; Humans; Nitric Oxide; omega-N-Methylarginine; Placenta; Pregnancy; Serotonin; Uterus; Vasoconstriction | 1994 |
Lack of contribution of nitric oxide to basal vasomotor tone in heart failure.
Topics: Adult; Aged; Arginine; Female; Forearm; Heart Failure; Humans; Male; Middle Aged; Nitric Oxide; omega-N-Methylarginine; Plethysmography; Regional Blood Flow; Vascular Resistance | 1994 |
Endothelium-dependent regulation of coronary tone in the neonatal pig.
Topics: Acetylcholine; Animals; Animals, Newborn; Arginine; Coronary Vessels; Endothelium, Vascular; Indomethacin; Muscle Tonus; Muscle, Smooth, Vascular; Myocardial Ischemia; Myocardial Reperfusion; Nitric Oxide; omega-N-Methylarginine; Perfusion; Swine; Vascular Resistance; Vasodilation | 1994 |
Sex differences in nitric oxide-mediated attenuation of vascular reactivity to vasopressin are abolished by gonadectomy.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Orchiectomy; Ovariectomy; Phenylephrine; Potassium Chloride; Rats; Rats, Sprague-Dawley; Sex Characteristics; Vasopressins | 1994 |
Pulmonary microvascular responses to protamine and histamine. Effects of cardiopulmonary bypass.
Topics: Animals; Arginine; Cardiopulmonary Bypass; Female; Heparin; Histamine; In Vitro Techniques; Indomethacin; Lung; Microcirculation; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Protamines; Sheep; Vascular Resistance | 1994 |
Nitric oxide inhibition normalizes splenocyte interleukin-10 synthesis in murine thermal injury.
Topics: Alcoholism; Animals; Arginine; Burns; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Interferon-gamma; Interleukin-10; Lymphocyte Activation; Male; Mice; Mice, Inbred BALB C; Nitric Oxide; Nitrites; omega-N-Methylarginine; Random Allocation; Spleen | 1994 |
Endotoxin-induced nitric oxide production in pulmonary artery endothelial cells is regulated by cytokines.
Topics: Animals; Arginine; Endothelium, Vascular; Escherichia coli; Interleukin-1; Lipopolysaccharides; Nitric Oxide; omega-N-Methylarginine; Pulmonary Artery; Swine; Time Factors; Tumor Necrosis Factor-alpha | 1994 |
Effect of Intralipid on hypoxic and angiotensin-II induced pulmonary vasoconstriction in the isolated rat lung.
Topics: Analysis of Variance; Angiotensin II; Animals; Arginine; Blood Pressure; Drug Interactions; Fat Emulsions, Intravenous; Hypoxia; In Vitro Techniques; Indomethacin; Male; Nitric Oxide; omega-N-Methylarginine; Prostaglandins; Pulmonary Artery; Pulmonary Gas Exchange; Rats; Rats, Wistar; Vasoconstriction | 1994 |
Nitric oxide release accounts for insulin's vascular effects in humans.
Topics: Acetylcholine; Adult; Arginine; Brachial Artery; Calorimetry, Indirect; Forearm; Glucose; Glucose Clamp Technique; Humans; Infusions, Intra-Arterial; Insulin; Male; Nitric Oxide; Nitroprusside; Norepinephrine; omega-N-Methylarginine; Regional Blood Flow; Vascular Resistance; Vasodilation | 1994 |
Effects of L-NMMA and indomethacin on arteriolar vasomotion in skeletal muscle microcirculation of conscious and anesthetized hamsters.
Topics: Acetylcholine; Anesthetics; Animals; Arginine; Arterioles; Cricetinae; Endothelium, Vascular; Indomethacin; Male; Mesocricetus; Microcirculation; Muscle, Skeletal; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Reference Values; Vasomotor System | 1994 |
Enhanced basal nitric oxide production in heart failure.
Topics: Arginine; Heart Failure; Humans; Nitric Oxide; omega-N-Methylarginine; Vascular Resistance | 1994 |
Contribution of endothelium-derived nitric oxide to exercise-induced vasodilation.
Topics: Acetylcholine; Adult; Arginine; Endothelium, Vascular; Female; Forearm; Humans; Male; Middle Aged; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Physical Exertion; Rest; Vasodilation; Vasomotor System | 1994 |
Role of nitric oxide in exercise-induced vasodilation of the forearm.
Topics: Adult; Angiotensin II; Arginine; Forearm; Humans; Injections, Intra-Arterial; Male; Nitric Oxide; omega-N-Methylarginine; Physical Exertion; Regional Blood Flow; Vasodilation | 1994 |
Administration of L-GN-monomethyl-arginine in a mouse islet transplant model.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Islets of Langerhans Transplantation; Mice; Mice, Inbred C57BL; Nitric Oxide; omega-N-Methylarginine; Transplantation, Heterotopic | 1994 |
Nitric oxide production increases with intraportal islet xenograft transplantation.
Topics: Animals; Arginine; Cell Separation; Humans; Islets of Langerhans; Islets of Langerhans Transplantation; Male; Nitrates; Nitric Oxide; Nitrites; omega-N-Methylarginine; Portal System; Rats; Rats, Inbred F344; Transplantation, Heterologous | 1994 |
Woodchuck hepatitis virus surface antigen induces nitric oxide synthesis in hepatocytes: possible role in hepatocarcinogenesis.
Topics: Animals; Antigens, Surface; Antigens, Viral; Arginine; Cells, Cultured; DNA Damage; Hepatitis B Virus, Woodchuck; Liver; Liver Neoplasms; Marmota; Models, Biological; Nitric Oxide; omega-N-Methylarginine; Rodent Diseases | 1994 |
Endothelin receptors mediating functional responses in human small arteries and veins.
Topics: Arginine; Arteries; Endothelin Receptor Antagonists; Endothelins; Humans; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Peptide Fragments; Peptides, Cyclic; Prostaglandin Antagonists; Receptors, Endothelin; Vasodilator Agents; Veins; Viper Venoms | 1994 |
NG-methyl-L-arginine, an inhibitor of nitric oxide formation, reverses IL-2-mediated hypotension in dogs.
Topics: Animals; Antineoplastic Agents; Arginine; Blood Pressure; Blood Urea Nitrogen; Cell Division; Creatinine; Dogs; Enzymes; Glioma; Hypotension; Interleukin-2; Killer Cells, Lymphokine-Activated; Leukocyte Count; Lymphocytes; Male; Monocytes; Nitric Oxide; omega-N-Methylarginine; Thrombocytopenia; Tumor Cells, Cultured | 1994 |
Human astrocytes inhibit Cryptococcus neoformans growth by a nitric oxide-mediated mechanism.
Topics: Arginine; Astrocytes; Cells, Cultured; Cryptococcus neoformans; Humans; Leucine; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine | 1994 |
Nitric oxide pathway-mediated relaxant effect of bradykinin in the guinea-pig isolated trachea.
Topics: Animals; Arginine; Bradykinin; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Female; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Trachea | 1994 |
Evidence for nicotine-induced skin flap ischemic necrosis in the pig.
Topics: Animals; Arginine; Blood Pressure; Body Temperature; Cardiac Output; Catecholamines; Dermatologic Surgical Procedures; Ischemia; Microcirculation; Necrosis; Nicotine; Nitric Oxide; Nitroarginine; Norepinephrine; omega-N-Methylarginine; Regional Blood Flow; Skin; Surgical Flaps; Swine | 1994 |
Nitric oxide influences neuronal activity in the nucleus tractus solitarius of rat brainstem slices.
Topics: Animals; Arginine; Brain Stem; In Vitro Techniques; Male; Medulla Oblongata; Neurons; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Rats; Rats, Inbred WKY | 1994 |
Nitric oxide decreases oxidant-mediated hepatocyte injury.
Topics: Acetaminophen; Animals; Arginine; Cytokines; Dose-Response Relationship, Drug; Glutathione; Liver; Male; Nitric Oxide; omega-N-Methylarginine; Oxidants; Rats; Rats, Sprague-Dawley | 1994 |
Modulation of lymphatic spontaneous contractions by EDRF.
Topics: Animals; Arginine; Dinoprost; Female; In Vitro Techniques; Lymphatic System; Male; Muscle Contraction; Nitric Oxide; omega-N-Methylarginine; Swine | 1994 |
Inhibition of hypoxia-induced relaxation of rabbit isolated coronary arteries by NG-monomethyl-L-arginine but not glibenclamide.
Topics: Adenosine; Adenosine Triphosphate; Animals; Arginine; Capsaicin; Coronary Vessels; Endothelium, Vascular; Glyburide; Hypoxia; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Potassium Channels; Rabbits; Tetrodotoxin; Theophylline | 1994 |
Interleukin-1 beta-induced nitric oxide production activates apoptosis in pancreatic RINm5F cells.
Topics: Animals; Apoptosis; Arginine; Cell Line; Cell Survival; DNA; DNA Damage; Interleukin-1; Islets of Langerhans; Kinetics; L-Lactate Dehydrogenase; Nitric Oxide; omega-N-Methylarginine; Recombinant Proteins; Time Factors | 1994 |
Hypertension and ageing impair acetylcholine-induced vasodilation in rats.
Topics: Acetylcholine; Aging; Animals; Arginine; Blood Pressure; Hemodynamics; Hypertension; Male; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vascular Resistance; Vasodilation | 1994 |
Contribution of nitric oxide to the endothelium-dependent hyperpolarization in rat aorta.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Carbachol; Cyclic GMP; Endothelium, Vascular; In Vitro Techniques; Membrane Potentials; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroglycerin; omega-N-Methylarginine; Rats; Rats, Wistar | 1994 |
Nitric oxide and prostaglandins interact to prevent hepatic damage during murine endotoxemia.
Topics: Animals; Arginine; Aspirin; Endotoxins; Female; Liver; Liver Diseases; Mice; Mice, Inbred BALB C; Nitric Oxide; omega-N-Methylarginine; Propionibacterium acnes; Prostaglandins | 1994 |
Diminished vascular response to inhibition of endothelium-derived nitric oxide and enhanced vasoconstriction to exogenously administered endothelin-1 in clinically healthy smokers.
Topics: Adult; Arginine; Blood Vessels; Endothelins; Endothelium, Vascular; Humans; Male; Middle Aged; Nitric Oxide; omega-N-Methylarginine; Reference Values; Smoking; Time Factors; Vasoconstriction; Vasomotor System | 1994 |
Selective loss of microvascular endothelial function in human hypercholesterolemia.
Topics: Acetylcholine; Adolescent; Adult; Aged; Arginine; Blood Vessels; Bradykinin; Endothelium, Vascular; Female; Forearm; Humans; Hypercholesterolemia; Male; Microcirculation; Middle Aged; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Regional Blood Flow; Vasodilation | 1994 |
L-arginine induces relaxation of human uterine artery with both intact and denuded endothelium.
Topics: Arginine; Arteries; Calmodulin; Dexamethasone; Endothelium, Vascular; Female; Humans; Imidazoles; In Vitro Techniques; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Regional Blood Flow; Stereoisomerism; Uterus | 1994 |
Reduced endothelium-dependent vasodilation by acetylcholine and bradykinin in isolated nitroglycerin-tolerant blood vessels.
Topics: Acetylcholine; Animals; Arginine; Bradykinin; Drug Tolerance; Endothelium, Vascular; In Vitro Techniques; Kinetics; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroglycerin; omega-N-Methylarginine; Pulmonary Artery; Swine; Vasodilation; Vasodilator Agents | 1994 |
Inhibition of macrophage Ia expression by nitric oxide.
Topics: Animals; Arginine; Cell Death; Female; Histocompatibility Antigens Class II; Interferon-gamma; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred C3H; Nitric Oxide; omega-N-Methylarginine; Penicillamine; Recombinant Proteins; S-Nitroso-N-Acetylpenicillamine | 1994 |
Heterogeneous spontaneous and interleukin-4-induced nitric oxide production by human monocytes.
Topics: Arginine; Cells, Cultured; Humans; Interleukin-4; Monocytes; Nitric Oxide; Nitrites; omega-N-Methylarginine; Recombinant Proteins | 1994 |
Selective Mycobacterium avium-induced production of nitric oxide by human monocyte-derived macrophages.
Topics: Arginine; Cell Differentiation; Cells, Cultured; Humans; Interferon-gamma; Macrophages; Monocytes; Mycobacterium avium; Nitric Oxide; omega-N-Methylarginine; Thromboxane A2; Tumor Necrosis Factor-alpha | 1994 |
Inhibition of spontaneous and mitogen-induced lymphocyte proliferation by murine bone marrow-derived macrophages: role of prostaglandins, nitric oxides and cell-to-cell contact.
Topics: Animals; Arginine; Bone Marrow Cells; Cell Adhesion; Cells, Cultured; Concanavalin A; Culture Media, Conditioned; Female; Indomethacin; Lipopolysaccharides; Lymphocyte Activation; Macrophages; Mice; Mice, Inbred Strains; Nitric Oxide; omega-N-Methylarginine; Prostaglandins | 1994 |
Function of nitric oxide during reperfusion of cold preserved small bowel grafts.
Topics: Analysis of Variance; Animals; Arginine; Cold Temperature; Glutaminase; Graft Survival; Guanidines; Intestinal Mucosa; Intestine, Small; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Organ Preservation; Rats; Rats, Inbred Lew; Reperfusion | 1994 |
Asbestos-induced nitric oxide production: synergistic effect with interferon-gamma.
Topics: Animals; Arginine; Asbestos, Crocidolite; Asbestos, Serpentine; Cells, Cultured; Drug Synergism; Interferon-gamma; Macrophages, Alveolar; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 1994 |
Cyclic GMP-independent relaxation and hyperpolarization with acetylcholine in guinea-pig coronary artery.
Topics: Acetylcholine; Animals; Arginine; Biological Factors; Coronary Vessels; Cyclic GMP; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Nitric Oxide; omega-N-Methylarginine; Oxyhemoglobins; Scorpion Venoms; Vasodilation | 1994 |
Nitric oxide production and neurotoxicity mediated by activated microglia from human versus mouse brain.
Topics: Aged; Aging; Animals; Animals, Newborn; Arginine; Brain; Cells, Cultured; gamma-Aminobutyric Acid; Humans; Interferon-gamma; L-Lactate Dehydrogenase; Lipopolysaccharides; Mice; Mice, Inbred BALB C; Microglia; Middle Aged; Neurons; Nitric Oxide; omega-N-Methylarginine; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1994 |
Dexamethasone blocks the interferon-gamma-mediated downregulation of the macrophage mannose receptor.
Topics: Animals; Arginine; Bone Marrow Cells; Dexamethasone; Dose-Response Relationship, Drug; Down-Regulation; Horseradish Peroxidase; Interferon-gamma; Lectins, C-Type; Macrophages; Mannose Receptor; Mannose-Binding Lectins; Nitric Oxide; omega-N-Methylarginine; Rats; Receptors, Cell Surface; RNA, Messenger | 1994 |
Nitric oxide increases renal blood flow by interacting with the sympathetic nervous system.
Topics: Animals; Arginine; Citrulline; Female; Kidney; Nitric Oxide; omega-N-Methylarginine; Rabbits; Renal Circulation; Sympathetic Nervous System | 1994 |
Nitric oxide inhibition in the treatment of the sepsis syndrome is detrimental to tissue oxygenation.
Topics: Animals; Arginine; Blood Pressure; Cardiac Output; Dogs; Endotoxins; Escherichia coli Infections; Hemodynamics; Nitric Oxide; omega-N-Methylarginine; Oxygen Consumption; Syndrome; Vascular Resistance | 1994 |
Modulation of cyclic guanosine monophosphate production during Escherichia coli septic shock.
Topics: Animals; Arginine; Bacteremia; Carbon Dioxide; Cyclic GMP; Escherichia coli Infections; Lactates; Lactic Acid; Male; Nitric Oxide; omega-N-Methylarginine; Rabbits; Shock, Septic | 1994 |
Bacteriostatic activity of BCG/PPD-activated macrophages against Mycobacterium fortuitum does not involve reactive nitrogen or oxygen intermediates.
Topics: Animals; Arginine; Cell Division; Macrophage Activation; Male; Mice; Mycobacterium bovis; Nitric Oxide; Nontuberculous Mycobacteria; omega-N-Methylarginine; Phagocytosis; Reactive Oxygen Species; Tuberculin | 1994 |
Capsaicin-induced gastric mucosal hyperemia and protection: the role of calcitonin gene-related peptide.
Topics: Animals; Arginine; Calcitonin Gene-Related Peptide; Capsaicin; Dinoprostone; DNA; Gastric Mucosa; Hyperemia; Male; Nitric Oxide; omega-N-Methylarginine; Peptide Fragments; Rats; Rats, Sprague-Dawley; Regional Blood Flow | 1994 |
Effect of endogenous and inhaled nitric oxide on the ventilation-perfusion relationships in oleic-acid lung injury.
Topics: Animals; Arginine; Dogs; Female; Male; Nitric Oxide; Oleic Acid; Oleic Acids; omega-N-Methylarginine; Respiratory Distress Syndrome; Ventilation-Perfusion Ratio | 1994 |
Experimental microsporidiosis in immunocompetent and immunodeficient mice and monkeys.
Topics: Animals; Antibodies, Protozoan; Arginine; Cytokines; Disease Models, Animal; Encephalitozoon; Encephalitozoonosis; Female; Immunocompetence; Interferon-gamma; Lipopolysaccharides; Macaca mulatta; Macrophages, Peritoneal; Mice; Mice, Inbred Strains; Microsporidiosis; Nitric Oxide; Nosema; omega-N-Methylarginine; Opportunistic Infections; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus | 1994 |
Effects of pyridoxalated hemoglobin polyoxyethylene conjugate and stroma-free hemoglobin on renal vascular responsiveness to vasoactive substances in isolated perfused rat kidney.
Topics: Acetylcholine; Angiotensin II; Animals; Arginine; Blood Substitutes; Hemoglobins; In Vitro Techniques; Male; Nitric Oxide; Nitroglycerin; Norepinephrine; omega-N-Methylarginine; Perfusion; Polyethylene Glycols; Rats; Rats, Wistar; Renal Circulation; Vasoconstrictor Agents; Vasodilator Agents | 1994 |
Altered nitric oxide production and exogenous nitric oxide do not affect the proliferation of rat mesangial cells.
Topics: Animals; Arginine; Cell Division; Cells, Cultured; Cyclic GMP; Glomerular Mesangium; Interleukin-1; Lipopolysaccharides; Molsidomine; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley | 1994 |
Generation of lymphokine-activated killer activity in rodents but not in humans is nitric oxide dependent.
Topics: Animals; Arginine; Cells, Cultured; Female; Hemoglobins; Humans; In Vitro Techniques; Killer Cells, Lymphokine-Activated; Leucine; Lysosomes; Mice; Mice, Inbred C57BL; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred F344; Time Factors | 1994 |
Coinduction of nitric oxide synthesis and intracellular nonheme iron-nitrosyl complexes in murine cytokine-treated fibroblasts.
Topics: Animals; Arginine; Biopterins; Cytokines; Electron Spin Resonance Spectroscopy; Escherichia coli; Ferric Compounds; Fibroblasts; Hypoxanthines; Interferon-gamma; Iron; Lipopolysaccharides; Mice; Nitric Oxide; omega-N-Methylarginine; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1994 |
Possible role of nitric oxide in malarial immunosuppression.
Topics: Animals; Arginine; Cell Division; Cells, Cultured; Concanavalin A; Erythrocytes; Humans; Immune Tolerance; Lymphocyte Activation; Malaria; Male; Mice; Mice, Inbred CBA; Nitric Oxide; omega-N-Methylarginine; Plasmodium chabaudi; Spleen | 1994 |
Involvement of Fc epsilon RII/CD23 and L-arginine dependent pathway in IgE-mediated activation of human eosinophils.
Topics: Antibodies, Monoclonal; Antihypertensive Agents; Arginine; Bone Marrow Cells; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Eosinophils; Hematopoietic Stem Cells; Humans; Immunoglobulin E; Kinetics; Molsidomine; omega-N-Methylarginine; Peroxides; Receptors, IgE; Superoxides; Tumor Necrosis Factor-alpha | 1994 |
Insulin-mediated skeletal muscle vasodilation is nitric oxide dependent. A novel action of insulin to increase nitric oxide release.
Topics: Adult; Analysis of Variance; Arginine; Blood Pressure; Body Mass Index; Dose-Response Relationship, Drug; Female; Femoral Artery; Humans; Infusions, Intra-Arterial; Insulin; Male; Methacholine Chloride; Muscles; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Regional Blood Flow; Time Factors; Vascular Resistance; Vasodilation | 1994 |
Nitric oxide and endothelium-dependent relaxation in tracheobronchial lymph vessels.
Topics: Animals; Arginine; Bronchi; Endothelium, Lymphatic; Female; Histamine; In Vitro Techniques; Lymphatic System; Male; Muscle Relaxation; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Perfusion; Trachea | 1994 |
Is nitric oxide involved in the tonic inhibition of central sympathetic outflow in humans?
Topics: Adult; Arginine; Blood Pressure; Heart Rate; Humans; Infusions, Intravenous; Microelectrodes; Muscles; Nitric Oxide; omega-N-Methylarginine; Peroneal Nerve; Phenylephrine; Sympathetic Nervous System | 1994 |
Non-classical glutamate receptors, blocked by both NMDA and non-NMDA antagonists, stimulate nitric oxide production in neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Arginine; Cells, Cultured; Corpus Striatum; Cyclic GMP; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Mice; N-Methylaspartate; Neurons; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Pregnancy; Quinoxalines; Quisqualic Acid; Receptors, Glutamate | 1993 |
Increased nitric oxide synthesis in ulcerative colitis.
Topics: Amino Acids; Arginine; Colitis, Ulcerative; Culture Techniques; Humans; Intestinal Mucosa; Nitric Oxide; omega-N-Methylarginine; Rectum | 1993 |
Adrenergic stimulation of cyclic GMP formation requires NO-dependent activation of cytosolic guanylate cyclase in rat pinealocytes.
Topics: Animals; Arginine; Cells, Cultured; Cyclic GMP; Cytosol; Enzyme Activation; Guanylate Cyclase; Methylene Blue; Nitric Oxide; omega-N-Methylarginine; Pineal Gland; Rats; Sympathomimetics | 1993 |
The role of TH1 and TH2 cells in a rodent malaria infection.
Topics: Animals; Antibodies, Protozoan; Arginine; CD4-Positive T-Lymphocytes; Cell Line; Female; Immunoglobulin G; Lymphocyte Depletion; Malaria; Mice; Mice, Inbred Strains; Nitrates; Nitric Oxide; omega-N-Methylarginine; Plasmodium chabaudi; T-Lymphocyte Subsets | 1993 |
Endothelium-derived nitric oxide reduces baseline venous tone in awake instrumented rats.
Topics: Animals; Arginine; Blood Pressure; Coronary Circulation; Dose-Response Relationship, Drug; Endothelium, Vascular; Ganglionic Blockers; Hexamethonium; Hexamethonium Compounds; Injections, Intravenous; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Vascular Resistance; Veins | 1993 |
Induction by endothelin-1 of epithelium-dependent relaxation of guinea-pig trachea in vitro: role for nitric oxide.
Topics: Animals; Arginine; Endothelins; Epithelium; Guanylate Cyclase; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; omega-N-Methylarginine; Oxyhemoglobins; Prostaglandins; Trachea | 1993 |
Notes on the acetylcholine-induced relaxation of porcine coronary arteries.
Topics: Acetylcholine; Animals; Arginine; Coronary Vessels; Cyclic GMP; Dose-Response Relationship, Drug; Drug Synergism; Endothelium, Vascular; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Radioimmunoassay; Swine; Vasoconstriction; Vasodilation | 1994 |
Furosemide and bumetanide, but not nedocromil sodium, modulate nonadrenergic relaxation in guinea pig trachea in vitro.
Topics: Animals; Arginine; Atropine; Bumetanide; Chymotrypsin; Drug Therapy, Combination; Electric Stimulation; Female; Furosemide; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle Relaxation; Nedocromil; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Premedication; Propranolol; Trachea; Vasoactive Intestinal Peptide | 1994 |
Combined effect of L-arginine and superoxide dismutase on the spastic basilar artery after subarachnoid hemorrhage in dogs.
Topics: Animals; Arginine; Basilar Artery; Dogs; Female; Ischemic Attack, Transient; Male; Nitric Oxide; omega-N-Methylarginine; Subarachnoid Hemorrhage; Superoxide Dismutase; Vasodilation | 1994 |
Nitric oxide mediates cat hindlimb cholinergic vasodilation induced by stimulation of posterior hypothalamus.
Topics: Animals; Arginine; Atropine; Cats; Cholinergic Fibers; Electric Stimulation; Hemodynamics; Hindlimb; Hypothalamus, Posterior; Isoproterenol; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Receptors, Adrenergic, beta; Vasodilation | 1993 |
Arginine analogues suppress antigen-specific and -nonspecific T lymphocyte proliferation.
Topics: Animals; Antigens, Bacterial; Arginine; Canavanine; Female; Guanidines; Listeria monocytogenes; Lymphocyte Activation; Mice; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; T-Lymphocytes | 1994 |
Mechanisms of cytokine-induced destruction of rat insulinoma cells: the role of nitric oxide.
Topics: Animals; Arginine; Cytokines; DNA; Insulinoma; Nitric Oxide; omega-N-Methylarginine; Pancreatic Neoplasms; Rats; Tumor Cells, Cultured | 1994 |
Contribution of endothelium-derived relaxing factor to exercise-induced vasodilation in humans.
Topics: Acetylcholine; Adult; Arginine; Endothelium, Vascular; Exercise; Female; Forearm; Humans; Male; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Plethysmography; Regional Blood Flow; Vasodilation | 1993 |
Disturbances in ex vivo vascular smooth muscle responses following exposure to Pasteurella haemolytica vaccines.
Topics: Animals; Arginine; Bacterial Vaccines; Carbachol; Ditiocarb; Endothelium, Vascular; Male; Mannheimia haemolytica; Muscle Relaxation; Muscle, Smooth, Vascular; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley | 1993 |
Arginine vasopressin induces endothelium-dependent vasodilatation of the pulmonary artery. V1-receptor-mediated production of nitric oxide.
Topics: Animals; Arginine; Arginine Vasopressin; Dogs; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Pulmonary Artery; Receptors, Vasopressin; Vasodilation | 1993 |
Endothelium dependency of contractile activity differs in infant and adult vertebral arteries.
Topics: Adult; Age Factors; Aged; Arginine; Child, Preschool; Endothelins; Endothelium, Vascular; Female; Humans; In Vitro Techniques; Infant; Infant, Newborn; Male; Middle Aged; omega-N-Methylarginine; Serotonin; Vasoconstriction; Vertebral Artery | 1994 |
Association between protective efficacy of antibodies to tumor necrosis factor and suppression of nitric oxide production in neonatal rats with fatal infection.
Topics: Animals; Animals, Newborn; Arginine; Bacteremia; Depression, Chemical; Dexamethasone; Isoantibodies; Nitrates; Nitric Oxide; Nitrites; omega-N-Methylarginine; Pseudomonas Infections; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 1993 |
Effects of nitric oxide on red blood cells: changes in erythrocyte resistance to hypotonic hemolysis and potassium efflux by experimental maneuvers that decrease nitric oxide.
Topics: Adult; Animals; Arginine; Cyclic GMP; Erythrocytes; Female; Hemolysis; Humans; Hypotonic Solutions; Kinetics; Male; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Potassium; Rats; Rats, Wistar | 1994 |
Effects of NG-monomethyl-L-arginine, indomethacin, and aspirin on the vasodepressor response to low doses of endothelin-1 and endothelin-3 in rats.
Topics: Animals; Arginine; Aspirin; Blood Pressure; Endothelins; Indomethacin; Male; Nitric Oxide; omega-N-Methylarginine; Prostaglandins; Rats; Rats, Wistar; Vascular Resistance | 1994 |
Endothelin-1 production by rat inner medullary collecting duct: effect of nitric oxide, cGMP, and immune cytokines.
Topics: Animals; Arginine; Atrial Natriuretic Factor; Base Sequence; Cells, Cultured; Cyclic GMP; Dibutyryl Cyclic GMP; DNA Primers; Endothelins; Interferon-gamma; Kidney Medulla; Kidney Tubules, Collecting; Kinetics; Male; Molecular Sequence Data; Nitric Oxide; omega-N-Methylarginine; Penicillamine; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; RNA, Messenger; S-Nitroso-N-Acetylpenicillamine; Time Factors; Tumor Necrosis Factor-alpha; Vasodilator Agents | 1994 |
Endothelium-dependent relaxation by angiotensin-converting enzyme inhibitors in canine femoral arteries.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Aspirin; Captopril; Dinoprost; Dipeptides; Dogs; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Femoral Artery; In Vitro Techniques; Indans; Isometric Contraction; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; omega-N-Methylarginine; Oxyhemoglobins; Superoxide Dismutase | 1994 |
Effect of potassium on vasodilation to acetylcholine in essential hypertension.
Topics: Acetylcholine; Adult; Arginine; Dose-Response Relationship, Drug; Drug Synergism; Female; Humans; Hypertension; Infusions, Intra-Arterial; Male; Middle Aged; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Potassium; Vasodilation | 1994 |
Regulation of hepatic endothelial cell and macrophage proliferation and nitric oxide production by GM-CSF, M-CSF, and IL-1 beta following acute endotoxemia.
Topics: Acute Disease; Animals; Arginine; Cell Division; Endothelium, Vascular; Endotoxins; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Interferon-gamma; Interleukin-1; Lipopolysaccharides; Liver; Macrophage Colony-Stimulating Factor; Macrophages; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley | 1994 |
Regulation of the immune response by nitric oxide differentially produced by T helper type 1 and T helper type 2 cells.
Topics: Animals; Arginine; Base Sequence; Cells, Cultured; Female; Interferon-gamma; Lymphocyte Activation; Mice; Molecular Sequence Data; Nitric Oxide; omega-N-Methylarginine; T-Lymphocytes, Helper-Inducer | 1994 |
Differing effects of vasopressin on regional cerebral blood flow of dogs following intracisternal vs. intra-arterial administration.
Topics: Animals; Arginine; Cerebrovascular Circulation; Cisterna Magna; Dogs; Female; Injections; Injections, Intra-Arterial; Male; Nitric Oxide; omega-N-Methylarginine; Vasopressins | 1994 |
cAMP analogues and cholera toxin stimulate the accumulation of nitrite in rat peritoneal macrophage cultures.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Arginine; Cells, Cultured; Cholera Toxin; Cyclic AMP; Cycloheximide; Dexamethasone; Lipopolysaccharides; Macrophages; Male; Nitric Oxide; omega-N-Methylarginine; Peritoneal Cavity; Rats; Rats, Wistar | 1994 |
Cigarette smoke extract contracts isolated porcine coronary arteries by superoxide anion-mediated degradation of EDRF.
Topics: Animals; Anions; Arginine; Arteries; Calcimycin; Catalase; Coronary Vessels; In Vitro Techniques; Isometric Contraction; Methylene Blue; Nicotine; Nitric Oxide; omega-N-Methylarginine; Smoke; Superoxide Dismutase; Superoxides; Swine; Vasoconstriction | 1994 |
EDRF in pulmonary resistance vessels from fetal lamb: stimulation by oxygen and bradykinin.
Topics: Animals; Arginine; Blood Vessels; Bradykinin; Indomethacin; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Oxygen; Pulmonary Circulation; Sheep; Vascular Resistance; Vasodilation | 1994 |
Prior episode of anoxia attenuates vasorelaxation in response to subsequent episode of anoxia.
Topics: Adenosine; Animals; Aorta; Arginine; Calcium; Endothelium, Vascular; Free Radicals; Hypoxia; In Vitro Techniques; Nitric Oxide; omega-N-Methylarginine; Prostaglandin-Endoperoxide Synthases; Purinergic P1 Receptor Antagonists; Rats; Recurrence; Vasodilation | 1994 |
Nitric oxide and energy production in articular chondrocytes.
Topics: Animals; Arginine; Cartilage, Articular; Cells, Cultured; Cytokines; Energy Metabolism; Humans; Interleukin-1; Lactates; Lactic Acid; Nitric Oxide; omega-N-Methylarginine; Penicillamine; Rabbits; Recombinant Proteins; S-Nitroso-N-Acetylpenicillamine; Transforming Growth Factor beta | 1994 |
Inducible production of nitric oxide in osteoblast-like cells and in fetal mouse bone explants is associated with suppression of osteoclastic bone resorption.
Topics: Animals; Arginine; Bone Resorption; Cells, Cultured; Female; Interferon-gamma; Interleukin-1; Lipopolysaccharides; Mice; Nitric Oxide; omega-N-Methylarginine; Osteoblasts; Osteoclasts; Pregnancy; Tumor Necrosis Factor-alpha | 1994 |
Nitric oxide and superoxide radical are involved in both initiation and development of adjuvant arthritis in rats.
Topics: Administration, Oral; Animals; Arginine; Arthritis, Experimental; Diclofenac; Female; Injections, Intraperitoneal; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Rats; Superoxide Dismutase; Superoxides | 1994 |
Nitric oxide production regulates cGMP formation and calcium influx in pancreatic acinar cells.
Topics: Animals; Arginine; Calcium; Carbachol; Cyclic GMP; Guinea Pigs; Indomethacin; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Pancreas; Rats | 1994 |
Light-activated release of nitric oxide from vascular smooth muscle of normotensive and hypertensive rats.
Topics: Animals; Aorta; Arginine; Hypertension; In Vitro Techniques; Kinetics; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Phenylephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reference Values; Systole; Time Factors; Ultraviolet Rays | 1994 |
Antihistoplasma effect of activated mouse splenic macrophages involves production of reactive nitrogen intermediates.
Topics: Animals; Arginine; Female; Histoplasma; Interferon-gamma; Macrophage Activation; Macrophages; Mice; Mice, Inbred C57BL; Nitrites; omega-N-Methylarginine; Recombinant Proteins; Spleen | 1994 |
Mitogen- and antigen-specific proliferation of T cells in murine toxoplasmosis is inhibited by reactive nitrogen intermediates.
Topics: Animals; Antigens, Protozoan; Arginine; Lymphocyte Activation; Lymphocyte Depletion; Macrophages; Mice; Mice, Inbred BALB C; Mice, Inbred CBA; Nitrites; omega-N-Methylarginine; Spleen; T-Lymphocytes; Toxoplasma; Toxoplasmosis, Animal | 1994 |
Inhibition of nitric oxide synthesis leads to reduced parasitemia in murine Trypanosoma brucei infection.
Topics: Animals; Arginine; Male; Mice; Mice, Inbred C3H; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Trypanosoma brucei brucei; Trypanosomiasis, African | 1994 |
Possible involvement of L-arginine-nitric oxide pathway in modulating regional blood flow to brown adipose tissue of rats.
Topics: Adipose Tissue, Brown; Animals; Arginine; Dose-Response Relationship, Drug; Laser-Doppler Flowmetry; Male; Microcirculation; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Wistar; Regional Blood Flow; Vascular Resistance | 1994 |
Nitric oxide generation following intrahepatic human-to-rat islet transplantation is blocked by NG-monomethyl-L-arginine.
Topics: Animals; Arginine; Humans; Interleukin-1; Islets of Langerhans Transplantation; Liver; Macrophages; Nitric Oxide; omega-N-Methylarginine; Rats; Transplantation, Heterologous; Transplantation, Heterotopic | 1994 |
Nitric oxide mediates Bordetella pertussis tracheal cytotoxin damage to the respiratory epithelium.
Topics: Aconitate Hydratase; Animals; Arginine; Cells, Cultured; Cricetinae; Cytotoxins; Epithelium; Interleukin-1; Iron; Mesocricetus; Nitric Oxide; omega-N-Methylarginine; Peptidoglycan; Trachea; Virulence Factors, Bordetella | 1993 |
Inhibitory nerve distribution and mediation of NANC relaxation by nitric oxide in horse airways.
Topics: Animals; Arginine; Atropine; Autonomic Nervous System; Bronchi; Electric Stimulation; Horses; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; omega-N-Methylarginine; Parasympathetic Nervous System; Propranolol; Respiratory Physiological Phenomena; Respiratory System; Trachea | 1994 |
Evidence of direct interaction between Kupffer cells and colon cancer cells: an ultrastructural study of the co-culture.
Topics: Animals; Arginine; Colonic Neoplasms; Free Radicals; Humans; In Vitro Techniques; Kupffer Cells; Male; Microscopy, Electron; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Wistar; Superoxide Dismutase; Time Factors; Tumor Cells, Cultured | 1994 |
The role of nitric oxide in IL-1 beta-mediated dysfunction of rodent islets of Langerhans. Implications for the function of intrahepatic islet grafts.
Topics: Animals; Arginine; Cells, Cultured; Glucose; Insulin; Interleukin-1; Islets of Langerhans; Islets of Langerhans Transplantation; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Lew; Time Factors | 1994 |
Role of endothelium in the maintenance of low pulmonary vascular tone in normal children.
Topics: Arginine; Blood Flow Velocity; Cardiac Catheterization; Child; Endothelium, Vascular; Female; Heart Defects, Congenital; Humans; Male; Nitric Oxide; omega-N-Methylarginine; Pulmonary Artery; Pulmonary Circulation; Vascular Resistance | 1994 |
Inhibitors of nitric oxide synthesis antagonize nitrous oxide antinociception in mice and rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Arginine; Cerebral Ventricles; Male; Mice; Morphine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrous Oxide; omega-N-Methylarginine; Pyrrolidines; Rats; Rats, Sprague-Dawley | 1994 |
Effects of regional inhibition of nitric oxide synthesis in intact porcine hearts.
Topics: Adenosine; Adenosine Diphosphate; Animals; Arginine; Coronary Circulation; Female; Hemodynamics; Hyperemia; Male; Myocardial Ischemia; Myocardium; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Oxygen Consumption; Swine; Time Factors | 1994 |
Mechanisms of hypertension in transgenic rats expressing the mouse Ren-2 gene.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Antihypertensive Agents; Arginine; Biphenyl Compounds; Blood Pressure; Endothelins; Female; Gene Expression; Hemodynamics; Hypertension; Imidazoles; Lisinopril; Losartan; Mice; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Reference Values; Tetrazoles | 1994 |
The macrophage-activating tetrapeptide tuftsin induces nitric oxide synthesis and stimulates murine macrophages to kill Leishmania parasites in vitro.
Topics: Animals; Arginine; Dexamethasone; Female; Interferon-gamma; Leishmania major; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Mice, Inbred BALB C; Nitric Oxide; omega-N-Methylarginine; Tuftsin | 1994 |
Mechanisms of CBF augmentation during hypoxia in cats: probable participation of prostacyclin, nitric oxide and adenosine.
Topics: Adenosine; Animals; Arginine; Caffeine; Cats; Cerebrovascular Circulation; Epoprostenol; Hypoxia; Indomethacin; Nitric Oxide; omega-N-Methylarginine | 1994 |
Enhanced production of nitric oxide by bone marrow cells and increased sensitivity to macrophage colony-stimulating factor (CSF) and granulocyte-macrophage CSF after benzene treatment of mice.
Topics: Animals; Arginine; Benzene; Bone Marrow; Bone Marrow Cells; Cell Division; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Lipopolysaccharides; Macrophage Colony-Stimulating Factor; Mice; Mice, Inbred BALB C; Nitric Oxide; omega-N-Methylarginine | 1994 |
Nonendothelial-derived nitric oxide activates the ATP-sensitive K+ channel of vascular smooth muscle cells.
Topics: Adenosine Triphosphate; Animals; Arginine; Cells, Cultured; Coronary Vessels; Endotoxins; Glyburide; Microelectrodes; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Potassium Channels; Swine | 1994 |
Spin trapping of nitric oxide produced in vivo in septic-shock mice.
Topics: Animals; Arginine; Chelating Agents; Electron Spin Resonance Spectroscopy; Female; Kidney; Lipopolysaccharides; Liver; Mice; Mice, Inbred ICR; Nitric Oxide; omega-N-Methylarginine; Organ Specificity; Shock, Septic; Sorbitol; Spin Labels; Thiocarbamates; Time Factors | 1994 |
Inhibition of nitric oxide causes exaggerated natriuresis in spontaneously hypertensive rats.
Topics: Animals; Arginine; Blood Pressure; Glomerular Filtration Rate; Hydrostatic Pressure; Infusions, Intravenous; Injections, Intravenous; Kidney; Male; Natriuresis; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reference Values; Species Specificity; Time Factors | 1994 |
EDRF suppresses chaotic pressure oscillations in isolated resistance artery without influencing intrinsic complexity.
Topics: Acetylcholine; Animals; Arginine; Arteries; Blood Pressure; Ear; Endothelium, Vascular; Fourier Analysis; Histamine; In Vitro Techniques; Male; Mathematics; Models, Cardiovascular; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nonlinear Dynamics; omega-N-Methylarginine; Oscillometry; Rabbits; Time Factors; Vascular Resistance | 1994 |
Influence of aortic baroreceptor denervation on adenosine receptor-mediated relaxation of isolated rat aorta.
Topics: Acetylcholine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Aorta, Thoracic; Arginine; Blood Pressure; Endothelium, Vascular; Heart Rate; In Vitro Techniques; Male; Muscle Denervation; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Phenylephrine; Pressoreceptors; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Theophylline | 1994 |
Macrophage-derived nitric oxide is involved in the depressed concanavalin A responsiveness of splenic lymphocytes from rats administered morphine in vivo.
Topics: Animals; Arginine; Concanavalin A; Immune Tolerance; In Vitro Techniques; Lymphocyte Activation; Lymphocytes; Macrophages; Male; Morphine; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Lew; Receptors, Adrenergic, beta; Spleen | 1994 |
Stimulation of HIV replication in mononuclear phagocytes by leukemia inhibitory factor.
Topics: Acetylcysteine; Arginine; Base Sequence; Cell Line; Cytokines; DNA Primers; Dose-Response Relationship, Drug; Gene Products, gag; Growth Inhibitors; HIV; HIV Core Protein p24; Humans; Interleukin-6; Kinetics; Leukemia Inhibitory Factor; Lymphokines; Molecular Sequence Data; Monocytes; NF-kappa B; Nitric Oxide; omega-N-Methylarginine; RNA, Messenger; Signal Transduction; Transcription, Genetic; Virus Replication | 1994 |
Gou-teng (from Uncaria rhynchophylla Miquel)-induced endothelium-dependent and -independent relaxations in the isolated rat aorta.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Atropine; Drugs, Chinese Herbal; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; omega-N-Methylarginine; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1994 |
Interferon-gamma and tumor necrosis factor-alpha exert their antirickettsial effect via induction of synthesis of nitric oxide.
Topics: Animals; Arginine; Cell Division; Cell Line; Cycloheximide; Drug Synergism; Fibroblasts; Interferon-gamma; Kinetics; Nitric Oxide; Nitrites; Nitroprusside; omega-N-Methylarginine; Osmolar Concentration; Rickettsia; Rickettsia Infections; Tumor Necrosis Factor-alpha | 1993 |
Nitric oxide does not mediate the attenuated pulmonary vascular reactivity of chronic pneumonia.
Topics: Acetylcholine; Animals; Arginine; Chronic Disease; Male; Nitric Oxide; omega-N-Methylarginine; Pneumonia; Pseudomonas Infections; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents | 1993 |
Nitric oxide and long-term synaptic depression in the rat hippocampus.
Topics: Animals; Arginine; Carbon Monoxide; Electric Stimulation; Hemoglobins; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Nitric Oxide; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Rats; Receptors, N-Methyl-D-Aspartate; Synapses | 1993 |
Bradykinin-induced release of PGI2 from aortic endothelial cell lines: responses mediated selectively by Ca2+ ions or a staurosporine-sensitive kinase.
Topics: 6-Ketoprostaglandin F1 alpha; Alkaloids; Animals; Aorta, Thoracic; Arginine; Bradykinin; Calcium; Cattle; Cell Line; Endothelium, Vascular; Epoprostenol; Ionomycin; Nitric Oxide; omega-N-Methylarginine; Phosphotransferases; Signal Transduction; Staurosporine | 1993 |
In vivo reactivity of resistance arterioles to activation of ATP-sensitive K+ channels.
Topics: Animals; Antihypertensive Agents; Arginine; Benzopyrans; Cheek; Cricetinae; Cromakalim; Male; Mesocricetus; Microcirculation; Muscle, Smooth, Vascular; Nitric Acid; omega-N-Methylarginine; Picolines; Potassium Channels; Pyrans; Pyrroles | 1993 |
Endogenous nitric oxide induced by interleukin-1 beta in rat islets of Langerhans and HIT-T15 cells causes significant DNA damage as measured by the 'comet' assay.
Topics: Animals; Arginine; Cell Line, Transformed; Cricetinae; DNA Damage; Humans; In Vitro Techniques; Interleukin-1; Islets of Langerhans; Kinetics; Nitrates; Nitric Oxide; Nitrites; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Recombinant Proteins | 1993 |
Endothelium-dependent vasodilator effects of the extract from Salviae Miltiorrhizae radix. A study on the identification of lithospermic acid B in the extracts.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Chromatography, Thin Layer; Drugs, Chinese Herbal; Endothelium, Vascular; In Vitro Techniques; Magnetic Resonance Spectroscopy; Methylene Blue; Muscle, Smooth, Vascular; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Plant Extracts; Rats; Spectrometry, Mass, Fast Atom Bombardment; Vasodilation | 1993 |
NG-monomethyl-L-arginine does not restore loss of hypoxic pulmonary vasoconstriction induced by TNF-alpha.
Topics: Animals; Arginine; Blood Cell Count; Blood Gas Analysis; Blood Pressure; Dogs; Epoprostenol; Filtration; Granulocytes; Hypoxia; Nitric Oxide; omega-N-Methylarginine; Perfusion; Pulmonary Circulation; Pulmonary Wedge Pressure; Respiration, Artificial; Tumor Necrosis Factor-alpha; Vascular Resistance; Vasoconstriction | 1993 |
Exercise increases inflammatory macrophage antitumor cytotoxicity.
Topics: Animals; Arginine; Body Weight; Cell Survival; Cytotoxicity Tests, Immunologic; Cytotoxins; Eating; Hydrocortisone; Inflammation; Leukocyte Count; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Nitric Oxide; omega-N-Methylarginine; Physical Conditioning, Animal | 1993 |
Suppressor macrophages in African trypanosomiasis inhibit T cell proliferative responses by nitric oxide and prostaglandins.
Topics: Animals; Arginine; Female; Immune Tolerance; Indomethacin; Interferon-gamma; Lymphocyte Activation; Macrophages; Mice; Nitric Oxide; omega-N-Methylarginine; Prostaglandins; T-Lymphocytes; Trypanosoma brucei rhodesiense; Trypanosomiasis, African; Tumor Necrosis Factor-alpha | 1993 |
Inhibition of endothelial derived relaxing factor (EDRF) aggravates ischemic acute renal failure in anesthetized rats.
Topics: Acute Kidney Injury; Animals; Arginine; Blood Pressure; Glomerular Filtration Rate; Ischemia; Kidney; Male; Nitric Oxide; omega-N-Methylarginine; Organ Size; Proteinuria; Rats; Reperfusion Injury; Sodium | 1993 |
Spinal nitric oxide synthesis inhibition blocks NMDA-induced thermal hyperalgesia and produces antinociception in the formalin test in rats.
Topics: Analgesics; Animals; Arginine; Behavior, Animal; Formaldehyde; Hot Temperature; Injections, Spinal; Male; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Spinal Cord | 1993 |
Nitric oxide-mediated, endothelium-dependent vasodilation is selectively attenuated in the postischemic extremity.
Topics: Acetylcholine; Animals; Arginine; Extremities; Ischemia; Male; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Reperfusion; Vascular Resistance; Vasodilation | 1993 |
Loss of hypoxic pulmonary vasoconstriction in chronic pneumonia is not mediated by nitric oxide.
Topics: Animals; Arginine; Blood Pressure; Cardiac Output; Hemodynamics; Hypoxia; Inflammation; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Pneumonia; Pseudomonas aeruginosa; Pseudomonas Infections; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Vascular Resistance; Vasoconstriction | 1993 |
Differential inhibition by NG-monomethyl-L-arginine of vasodilator effects of acetylcholine and methacholine in human forearm vasculature.
Topics: Acetylcholine; Adult; Arginine; Forearm; Humans; Infant, Newborn; Infusions, Intravenous; Methacholine Compounds; Middle Aged; omega-N-Methylarginine; Plethysmography; Regional Blood Flow; Vasodilator Agents | 1993 |
The role of nitric oxide in cholinergic neurotransmission in rat trachea.
Topics: Acetylcholine; Animals; Arginine; Bucladesine; Electric Stimulation; In Vitro Techniques; Male; Methylene Blue; Muscle Contraction; Muscle, Smooth; Neuropeptides; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Parasympathetic Nervous System; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Trachea; Vasoactive Intestinal Peptide | 1993 |
Involvement of alpha-adrenoceptors in the endothelium-dependent depression of noradrenaline-induced contraction in rat aorta.
Topics: Animals; Aorta, Thoracic; Arginine; Clonidine; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Norepinephrine; omega-N-Methylarginine; Phenylephrine; Rats; Rats, Inbred WKY; Receptors, Adrenergic, alpha; Yohimbine | 1993 |
Differential regulation of cytokine production by nitric oxide.
Topics: Animals; Arginine; Cells, Cultured; Cytokines; Interleukin-2; Interleukin-3; Lymph Nodes; Macrophages; Male; Mice; Mice, Inbred CBA; Nitric Oxide; omega-N-Methylarginine; Picryl Chloride; Spleen; T-Lymphocytes | 1993 |
Determination of kainic acid-induced release of nitric oxide using a novel hemoglobin trapping technique with microdialysis.
Topics: Animals; Arginine; Hippocampus; Kainic Acid; Kinetics; Male; Microdialysis; Nitric Oxide; omega-N-Methylarginine; Oxyhemoglobins; Rats; Time Factors | 1993 |
Endothelial control of the pulmonary circulation in normal and chronically hypoxic rats.
Topics: Almitrine; Animals; Arginine; Atrial Natriuretic Factor; Blood Pressure; Chronic Disease; Endothelins; Endothelium, Vascular; Hypoxia; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Pulmonary Circulation; Rats; Rats, Wistar; Respiration; Vasoconstriction | 1993 |
Macrophage-generated nitric oxide as cytotoxic factor in destruction of alginate-encapsulated islets. Protection by arginine analogs and/or coencapsulated erythrocytes.
Topics: Alginates; Animals; Arginine; Culture Techniques; Cytotoxicity, Immunologic; Erythrocytes; Female; Glucuronic Acid; Hexuronic Acids; Islets of Langerhans; Islets of Langerhans Transplantation; Macrophage Activation; Macrophages; Male; Membranes; Nitric Oxide; omega-N-Methylarginine; Penicillamine; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine | 1993 |
Possible involvement of nitric oxide in arginine-induced analgesia.
Topics: Analgesics; Animals; Arginine; Cyclic GMP; Injections, Intraventricular; Male; Mice; Nitric Oxide; Nitroprusside; Nociceptors; omega-N-Methylarginine; Pain Threshold | 1993 |
The role of nitric oxide in endothelium-dependent vasodilation of hypercholesterolemic patients.
Topics: Acetylcholine; Adult; Aged; Arginine; Blood Flow Velocity; Endothelium, Vascular; Female; Forearm; Humans; Hypercholesterolemia; Male; Middle Aged; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Vascular Resistance; Vasodilation | 1993 |
In vitro femoral arterial responses to vasoconstrictor and vasodilator agents in endotoxin shock.
Topics: Acetylcholine; Animals; Arginine; Arginine Vasopressin; Bradykinin; Femoral Artery; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Phenylephrine; Potassium Chloride; Rats; Rats, Wistar; Shock, Septic; Vasoconstrictor Agents; Vasodilator Agents | 1994 |
Nitric oxide production from a macrophage cell line: interaction with autologous and allogeneic lymphocytes.
Topics: Animals; Antibodies; Arginine; Ascitic Fluid; CD3 Complex; Cell Count; Cell Division; Cell Line; Concanavalin A; Enterotoxins; Macrophages; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Nitric Oxide; omega-N-Methylarginine; Spleen; T-Lymphocytes | 1993 |
Constriction/dilatation of the cerebral microvessels by intravascular endothelin-1 in cats.
Topics: Animals; Arginine; Blood Pressure; Blood Volume; Carotid Arteries; Cats; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Endothelins; Female; Injections, Intra-Arterial; Male; Microcirculation; Nitric Oxide; omega-N-Methylarginine; Peptides, Cyclic; Time Factors; Vasoconstriction; Vasodilation | 1994 |
Responses of cerebral arterioles to activation of beta-adrenergic receptors during diabetes mellitus.
Topics: Animals; Arginine; Arterioles; Cerebrovascular Circulation; Colforsin; Diabetes Mellitus, Experimental; Isoproterenol; Nitric Oxide; Nitroglycerin; omega-N-Methylarginine; Pia Mater; Rats; Receptors, Adrenergic, beta; Vasodilation | 1994 |
Autocrine regulation of the production of the gaseous messenger nitric oxide in a glioblastoma cell line.
Topics: Arginine; Cytokines; Dexamethasone; Glioblastoma; In Vitro Techniques; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Time Factors; Tumor Cells, Cultured | 1994 |
Comparative studies with 15(R)-15-methylprostaglandin E2 (arbaprostil) in rat femoral arterial preparations in vivo and in vitro.
Topics: Acetylcholine; Animals; Arbaprostil; Arginine; Dinoprostone; Endothelium, Vascular; Femoral Artery; Hemodynamics; In Vitro Techniques; Injections, Intra-Arterial; Male; Methylene Blue; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley | 1993 |
Mechanisms of endothelin-1-induced pulmonary vasodilatation in neonatal pigs.
Topics: Animals; Animals, Newborn; Arginine; Endothelins; Female; Glyburide; Hemoglobins; In Vitro Techniques; Indomethacin; Male; Nitric Oxide; omega-N-Methylarginine; Peptide Fragments; Perfusion; Potassium Channels; Pulmonary Circulation; Receptors, Endothelin; Swine; Vasodilation | 1993 |
Endothelium-derived relaxing factor inhibition and the pressor response to norepinephrine in the pregnant rat.
Topics: Analysis of Variance; Animals; Arginine; Blood Pressure; Dose-Response Relationship, Drug; Female; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley | 1994 |
MDHM, a macrophage-activating product of Mycoplasma fermentans, stimulates murine macrophages to synthesize nitric oxide and become tumoricidal.
Topics: Animals; Arginine; Cytotoxicity, Immunologic; Female; Interferon-gamma; Lipopolysaccharides; Macrophage Activation; Macrophages, Peritoneal; Mast-Cell Sarcoma; Mice; Mice, Inbred C3H; Mycoplasma fermentans; Nitric Oxide; omega-N-Methylarginine; Recombinant Proteins; Tumor Cells, Cultured | 1993 |
Inhibition of nitric oxide formation does not protect murine cortical cell cultures from N-methyl-D-aspartate neurotoxicity.
Topics: Animals; Arginine; Cell Death; Cells, Cultured; Cerebral Cortex; Cyclic GMP; Dextrorphan; Mice; N-Methylaspartate; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Rats | 1993 |
The effects of nitric oxide on chondrocytes and lymphocytes.
Topics: Animals; Arginine; Cartilage, Articular; Cell Division; Cells, Cultured; Concanavalin A; Culture Media, Conditioned; Kinetics; Lipopolysaccharides; Lymphocyte Activation; Lymphocytes; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred F344; Spleen; Time Factors | 1993 |
Nitric oxide increases dopamine and serotonin release in the medial preoptic area.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Arginine; Dopamine; Homovanillic Acid; Male; Microdialysis; Nitric Oxide; omega-N-Methylarginine; Preoptic Area; Rats; Serotonin; Stereoisomerism | 1993 |
Nitric oxide participates in calcium-mediated regulation of renin release.
Topics: Angiotensin II; Animals; Arginine; Calcium; Calmodulin; Egtazic Acid; In Vitro Techniques; Isoproterenol; Kidney Cortex; Kinetics; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Renin; Sulfonamides | 1994 |
Increased production of nitric oxide in coronary arteries during congestive heart failure.
Topics: Acetylcholine; Adenosine Diphosphate; Animals; Arginine; Atrial Natriuretic Factor; Azepines; Blood Pressure; Calcimycin; Cardiac Output; Coronary Vessels; Dinoprost; Dogs; Endothelium, Vascular; Femoral Artery; Heart Failure; Hemodynamics; In Vitro Techniques; Indomethacin; Isometric Contraction; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Pertussis Toxin; Reference Values; Renal Artery; Renin; Vascular Resistance; Virulence Factors, Bordetella | 1994 |
Relaxation of vascular smooth muscle induced by low-power laser radiation.
Topics: Animals; Aorta; Arginine; Dose-Response Relationship, Radiation; Indomethacin; Light; Models, Chemical; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Protoporphyrins; Rabbits; Ultraviolet Rays; Vasodilation | 1993 |
Role of endothelium in sexual dimorphism in vasopressin-induced contraction of rat aorta.
Topics: Animals; Aorta; Arginine; Arginine Vasopressin; Endothelium, Vascular; Female; Indomethacin; Male; Nitric Oxide; omega-N-Methylarginine; Osmolar Concentration; Phenylephrine; Rats; Rats, Sprague-Dawley; Sex Characteristics; Vasoconstriction | 1993 |
Role of L-arginine-derived nitric oxide in cholinergic dilation of gastric arterioles.
Topics: Acetylcholine; Administration, Topical; Animals; Arginine; Arterioles; Injections, Intravenous; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Stomach; Vasodilation | 1993 |
Inhibition of nitric oxide synthesis in forearm vasculature of insulin-dependent diabetic patients: blunted vasoconstriction in patients with microalbuminuria.
Topics: Adult; Albuminuria; Arginine; Carbachol; Diabetes Mellitus, Type 1; Female; Forearm; Humans; Male; Middle Aged; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Regional Blood Flow; Vasodilation | 1993 |
Characterization of endothelin receptors and localization of 125I-endothelin-1 binding sites in human umbilical artery.
Topics: Arginine; Binding Sites; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelins; Endothelium, Vascular; Humans; Iodine Radioisotopes; Muscle Contraction; Muscle, Smooth, Vascular; Nicardipine; omega-N-Methylarginine; Peptides, Cyclic; Receptors, Endothelin; Umbilical Arteries; Vasoconstriction; Vasoconstrictor Agents; Verapamil; Viper Venoms | 1993 |
Vascular responses to endothelin-1 following inhibition of nitric oxide synthesis in the conscious rat.
Topics: Animals; Arginine; Blood Pressure; Capillary Permeability; Consciousness; Dose-Response Relationship, Drug; Endothelins; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Wistar | 1993 |
Human monocytes are stimulated for nitric oxide release in vitro by some tumor cells but not by cytokines and lipopolysaccharide.
Topics: Animals; Arginine; Cells, Cultured; Cytokines; Emetine; Humans; In Vitro Techniques; Interferon-gamma; Lipopolysaccharides; Male; Mice; Mice, Inbred CBA; Monocytes; Nitric Oxide; omega-N-Methylarginine; Tumor Cells, Cultured | 1994 |
The role of endogenous nitric oxide and platelet-activating factor in hypoxia-induced intestinal injury in rats.
Topics: Animals; Arginine; Hypoxia; Intestines; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Peroxidase; Platelet Activating Factor; Rats; Rats, Sprague-Dawley | 1994 |
Evidence for the involvement of macrophage-derived nitric oxide in the modulation of immune status by a conditioned aversive stimulus.
Topics: Animals; Arginine; Concanavalin A; Conditioning, Psychological; Electroshock; Interferon-gamma; Lymphocyte Activation; Macrophages; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Lew | 1994 |
Does a general alteration in nitric oxide synthesis system occur in spontaneously hypertensive rats?
Topics: Animals; Arginine; Cell Division; Hypertension; Lymphocytes; Macrophages; Male; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1994 |
Modulation by nitric oxide of platelet-activating factor-induced albumin extravasation in the conscious rat.
Topics: Albumins; Animals; Arginine; Blood Pressure; Capillary Permeability; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Platelet Activating Factor; Rats; Rats, Wistar | 1993 |
Regional and cardiac haemodynamic effects of NG, NG,dimethyl-L-arginine and their reversibility by vasodilators in conscious rats.
Topics: Animals; Arginine; Glutathione; Hemodynamics; Hydralazine; Male; Nitroprusside; Nitroso Compounds; omega-N-Methylarginine; Penicillamine; Rats; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione; Vasodilator Agents | 1993 |
EDRF release from canine coronary artery by lectins.
Topics: Animals; Arginine; Atropine; Coronary Vessels; Dogs; Endothelium, Vascular; In Vitro Techniques; Lectins; Nitric Oxide; omega-N-Methylarginine; Wheat Germ Agglutinins | 1993 |
Drugs which modulate nitric oxide homeostasis are likely to provide therapeutic benefit in cardiovascular disease.
Topics: Animals; Arginine; Cardiovascular Diseases; Homeostasis; Humans; Mice; Nitric Oxide; omega-N-Methylarginine; Rats; Shock, Septic; Vasodilation | 1993 |
Protection against gastric ischemia-reperfusion injury by nitric oxide generators.
Topics: Acetylcholine; Animals; Arginine; Blood Pressure; Cell Movement; Gastric Mucosa; Male; Neutrophils; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Papaverine; Rats; Reperfusion Injury | 1994 |
Endothelium-dependent vasoregulation of coronary artery diameter and blood flow.
Topics: Acetylcholine; Animals; Arginine; Coronary Circulation; Coronary Vessels; Endothelium, Vascular; Humans; Myocardial Ischemia; Nitric Oxide; omega-N-Methylarginine; Vasodilation | 1993 |
Effect of inhibition of nitric oxide synthesis on epicardial coronary artery caliber and coronary blood flow in humans.
Topics: Acetylcholine; Arginine; Coronary Angiography; Coronary Circulation; Coronary Vessels; Female; Humans; Male; Middle Aged; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Vasodilation | 1993 |
Role of endothelium-derived nitric oxide in hemodynamic adaptations after graded renal mass reduction.
Topics: Adaptation, Physiological; Animals; Arginine; Endothelium, Vascular; Hemodynamics; Homeostasis; Male; Nephrectomy; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Renal Circulation | 1993 |
NG-methyl-L-arginine restores arterial pressure in hemorrhaged rats.
Topics: Animals; Arginine; Arteries; Blood Pressure; Disease Models, Animal; Hypotension; Male; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Shock, Hemorrhagic; Vascular Resistance | 1993 |
Involvement of nitric oxide on the cytokine induced growth of glial cell.
Topics: Animals; Arginine; Cell Division; Cytokines; Glioma; Humans; Interferon-gamma; Interleukin-6; Isoquinolines; Kinetics; Lymphotoxin-alpha; Neuroglia; Nitric Oxide; omega-N-Methylarginine; Protein Kinase Inhibitors; Rats; Recombinant Proteins; Stereoisomerism; Sulfonamides; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1993 |
Tumor necrosis factor-alpha inhibits endothelium-dependent relaxation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Arginine; Cattle; Endothelium, Vascular; Histamine; Ibuprofen; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; omega-N-Methylarginine; Pentoxifylline; Potassium Chloride; Prostaglandin Endoperoxides, Synthetic; Pulmonary Artery; Pulmonary Veins; Tumor Necrosis Factor-alpha; Vasoconstrictor Agents | 1993 |
Effect of in vivo inhibition of nitric oxide production in murine leishmaniasis.
Topics: Animals; Arginine; Cachexia; Female; Immunity, Innate; Leishmaniasis; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Nitric Oxide; omega-N-Methylarginine | 1993 |
Characterization of the immunosuppressive effects of nitric oxide in graft vs host disease.
Topics: Animals; Arginine; Concanavalin A; Female; Graft vs Host Disease; Immune Tolerance; Lipopolysaccharides; Lymphocyte Activation; Macrophages; Mice; Mice, Inbred Strains; Nitrates; Nitric Oxide; Nitrites; omega-N-Methylarginine; Peritoneal Cavity; Trinitrobenzenes | 1993 |
Nitric oxide mediates lipopolysaccharide-induced alteration of mitochondrial function in cultured hepatocytes and isolated perfused liver.
Topics: Animals; Arginine; Cells, Cultured; Fluorescence; Image Processing, Computer-Assisted; In Vitro Techniques; Kupffer Cells; Lipopolysaccharides; Liver; Male; Microscopy, Fluorescence; Mitochondria; NAD; Nitric Oxide; omega-N-Methylarginine; Perfusion; Rats; Rats, Wistar; Rhodamine 123; Rhodamines | 1993 |
Responses of cerebral arterioles in diabetic rats to activation of ATP-sensitive potassium channels.
Topics: Adenosine Triphosphate; Animals; Arginine; Arterioles; Cerebrovascular Circulation; Diabetes Mellitus, Experimental; Male; Nitroglycerin; omega-N-Methylarginine; Pia Mater; Picolines; Potassium Channels; Pyrans; Rats; Rats, Sprague-Dawley | 1993 |
Increasing oxygen tension dilates fetal pulmonary circulation via endothelium-derived relaxing factor.
Topics: Animals; Arginine; Fetus; Hemodynamics; Hyperbaric Oxygenation; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Oxygen; Pulmonary Circulation; Sheep; Vasodilation | 1993 |
Role of nitric oxide in leukotriene C4-induced increases in microvascular transport.
Topics: Animals; Arginine; Biological Transport; Capillary Permeability; Cheek; Cricetinae; Male; Mesocricetus; Nitric Oxide; omega-N-Methylarginine; SRS-A; Venules | 1993 |
Direct electrochemical measurement of nitric oxide released from human platelets.
Topics: Arginine; Blood Platelets; Collagen; Electrochemistry; Humans; In Vitro Techniques; Kinetics; Nitric Oxide; omega-N-Methylarginine; Platelet Aggregation; Thrombin | 1993 |
Plasmodium berghei: is nitric oxide involved in the pathogenesis of mouse cerebral malaria?
Topics: Animals; Arginine; Disease Susceptibility; Malaria, Cerebral; Mice; Mice, Inbred Strains; Nitrates; Nitric Oxide; Nitrites; Nitroarginine; omega-N-Methylarginine; Plasmodium berghei; Plasmodium chabaudi | 1993 |
Protection of islet cells from inflammatory cell death in vitro.
Topics: Animals; Arachidonic Acid; Arginine; Benzamides; Cell Death; Cells, Cultured; Cytotoxicity, Immunologic; DNA Repair; Islets of Langerhans; Macrophages; omega-N-Methylarginine; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar; Reactive Oxygen Species | 1993 |
Modulation of cholinergic neural bronchoconstriction by endogenous nitric oxide and vasoactive intestinal peptide in human airways in vitro.
Topics: Acetylcholine; Adolescent; Adult; Arginine; Atropine; Bronchi; Child; Child, Preschool; Choline; Electric Stimulation; Female; Humans; In Vitro Techniques; Isomerism; Lung; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Tetrodotoxin; Trachea; Vasoactive Intestinal Peptide | 1993 |
Induction of endothelium-dependent relaxation in the rat aorta by IRL 1620, a novel and selective agonist at the endothelin ETB receptor.
Topics: Animals; Aorta, Thoracic; Arginine; Calcium; Carbachol; Endothelins; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; omega-N-Methylarginine; Peptide Fragments; Potassium Chloride; Rats; Rats, Wistar; Receptors, Endothelin; Verapamil | 1993 |
Lanthanide "blockade" of antigen-presenting cells suppresses lymphocyte proliferation by inducing nitric oxide synthesis.
Topics: Animals; Antigen-Presenting Cells; Arginine; B-Lymphocytes; Dinoprostone; Edetic Acid; Gadolinium; Lymphocyte Activation; Macrophages; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Lew | 1993 |
Endothelium-dependent relaxation and interaction between indomethacin and L-NG-monomethylarginine in coronary bypass grafts.
Topics: Arginine; Coronary Artery Bypass; Coronary Circulation; Drug Synergism; Humans; Indomethacin; Nitric Oxide; omega-N-Methylarginine; Vasodilation | 1993 |
The schistosomulicidal activity and the production of IL-1 and TNF-alpha by peritoneal macrophages from infected mice and their potentiation by muramyl tripeptide-phosphatidyl ethanolamine (MTP-PE) treatment.
Topics: Acetylmuramyl-Alanyl-Isoglutamine; Adjuvants, Immunologic; Animals; Arginine; Biological Assay; Cells, Cultured; Drug Carriers; Immunity, Cellular; Interleukin-1; Interleukin-2; Liposomes; Macrophages; Male; Mice; Mice, Inbred ICR; omega-N-Methylarginine; Peritoneum; Phosphatidylethanolamines; Schistosoma mansoni; Schistosomiasis mansoni; Spleen; Time Factors; Tumor Necrosis Factor-alpha | 1993 |
Nitric oxide synthesis inhibitors induce airway hyperresponsiveness in the guinea pig in vivo and in vitro. Role of the epithelium.
Topics: Analysis of Variance; Animals; Arginine; Bronchi; Bronchial Hyperreactivity; Dose-Response Relationship, Drug; Drug Interactions; Epithelium; Guinea Pigs; Histamine; In Vitro Techniques; Male; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine | 1993 |
Rat splenocytes inhibit antigen-specific lymphocyte proliferation through a reactive nitrogen intermediate (RNI)-dependent mechanism and exhibit increased RNI production in response to IFN-gamma.
Topics: Animals; Antigens; Arginine; Cells, Cultured; Dose-Response Relationship, Drug; Female; Interferon-gamma; Lymphocyte Activation; Nitric Oxide; Nitrites; omega-N-Methylarginine; Rats; Rats, Inbred Lew; Spleen; T-Lymphocytes, Regulatory | 1993 |
Vasodilatory effect of arginine vasopressin is mediated by nitric oxide in human forearm vessels.
Topics: Adult; Arginine; Arginine Vasopressin; Dose-Response Relationship, Drug; Forearm; Humans; Male; Nitric Oxide; omega-N-Methylarginine; Regional Blood Flow; Vasodilation | 1993 |
Autoinhibition of murine macrophage-mediated oxidation of low-density lipoprotein by nitric oxide synthesis.
Topics: Animals; Arginine; Cells, Cultured; Interferon-gamma; Lipopolysaccharides; Lipoproteins, LDL; Macrophage Activation; Macrophages; Mice; Nitric Oxide; omega-N-Methylarginine; Onium Compounds; Oxidation-Reduction | 1993 |
Actions and interactions of NG-substituted analogues of L-arginine on NANC neurotransmission in the bovine retractor penis and rat anococcygeus muscles.
Topics: Animals; Arginine; Autonomic Nervous System; Cattle; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitroarginine; omega-N-Methylarginine; Penis; Rats; Synaptic Transmission | 1993 |
Nitric oxide mediates cytokine-induced inhibition of insulin secretion by human islets of Langerhans.
Topics: Arginine; Cyclic GMP; Diabetes Mellitus, Type 1; Electron Spin Resonance Spectroscopy; Humans; In Vitro Techniques; Insulin; Insulin Secretion; Interferon-gamma; Interleukin-1; Islets of Langerhans; Nitric Oxide; Nitrites; omega-N-Methylarginine; Recombinant Proteins; Secretory Rate; Tumor Necrosis Factor-alpha | 1993 |
Ouabain enhances basal release of nitric oxide from carotid artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arginine; Bradykinin; Calcium; Carotid Arteries; In Vitro Techniques; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Ouabain; Prostaglandin Endoperoxides, Synthetic; Sodium-Potassium-Exchanging ATPase; Swine; Vasodilation | 1993 |
Endothelium-dependent vasorelaxation evoked by desmopressin and involvement of nitric oxide in rat aorta.
Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Aorta; Arginine; Cyclic GMP; Deamino Arginine Vasopressin; Endothelium, Vascular; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Wistar; Superoxide Dismutase; Vasodilation | 1993 |
Involvement of endothelium-derived relaxing factor in the pressure control of renin secretion from isolated perfused kidney.
Topics: Acetylcholine; Angiotensin I; Animals; Arginine; Atrial Natriuretic Factor; Cyclic GMP; Diuresis; In Vitro Techniques; Isoproterenol; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Perfusion; Pressure; Rats; Rats, Inbred Strains; Renin | 1993 |
The calmodulin antagonist calmidazolium stimulates release of nitric oxide in neuroblastoma N1E-115 cells.
Topics: Animals; Arginine; Calmodulin; Cyclic GMP; Dose-Response Relationship, Drug; Hemoglobins; Imidazoles; Kinetics; Mice; Neuroblastoma; Nitric Oxide; omega-N-Methylarginine; Tumor Cells, Cultured | 1993 |
Role of nitric oxide and angiotensin II in the regulation of sympathetic nerve activity in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Biphenyl Compounds; Blood Pressure; Dipeptides; Heart Rate; Imidazoles; Lisinopril; Losartan; Male; Nitric Oxide; Oligopeptides; omega-N-Methylarginine; Pressoreceptors; Rats; Rats, Inbred SHR; Reflex; Tetrazoles | 1993 |
Role of endothelium in biphasic hypoxic response of the isolated pulmonary artery in the rat.
Topics: Animals; Arginine; Cyclic GMP; Endothelium, Vascular; Hypoxia; Male; Nitric Oxide; omega-N-Methylarginine; Pulmonary Artery; Rats; Rats, Sprague-Dawley | 1993 |
Effect of NG-monomethyl-L-arginine on the beta-adrenoceptor-mediated relaxation of rat mesenteric resistance arteries.
Topics: Animals; Arginine; In Vitro Techniques; Isoproterenol; Male; Mesenteric Arteries; Muscle Relaxation; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred WKY; Receptors, Adrenergic, beta | 1993 |
Changes in mechanisms of monocyte/macrophage-mediated cytotoxicity during culture. Reactive oxygen intermediates are involved in monocyte-mediated cytotoxicity, whereas reactive nitrogen intermediates are employed by macrophages in tumor cell killing.
Topics: Arginine; Cells, Cultured; Cytotoxicity, Immunologic; DNA, Neoplasm; Humans; Leukemia, Erythroblastic, Acute; Luminescent Measurements; Macrophages; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Nitric Oxide; Nitrites; omega-N-Methylarginine; Reactive Oxygen Species; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Nonheme iron-nitrosyl complex formation in rat hepatocytes: detection by electron paramagnetic resonance spectroscopy.
Topics: Animals; Arginine; Electron Spin Resonance Spectroscopy; Interferon-gamma; Interleukin-1; Iron; Lipopolysaccharides; Liver; Male; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Propionibacterium acnes; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 1993 |
Influence of endothelium on induction of the L-arginine-nitric oxide pathway in rat aortas.
Topics: Animals; Aorta; Arginine; Cyclic GMP; Cycloheximide; Endothelium, Vascular; Male; Methylene Blue; Neural Pathways; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Rats; Rats, Wistar; Time Factors | 1993 |
Resistance to nitric oxide in Mycobacterium avium complex and its implication in pathogenesis.
Topics: Animals; Arginine; Drug Resistance, Microbial; Hydrogen-Ion Concentration; Immunity, Cellular; Interferon-gamma; Macrophage Activation; Macrophages, Alveolar; Male; Mycobacterium avium; Nitric Oxide; Nitrites; omega-N-Methylarginine; Phagocytosis; Rats; Rats, Inbred F344; Rats, Wistar; Recombinant Proteins; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate; Tuberculosis | 1993 |
Nitric oxide affects mammalian distal colonic smooth muscle by tonic neural inhibition.
Topics: Acetylcholine; Animals; Arginine; Colon; Cyclic GMP; In Vitro Techniques; Isometric Contraction; Male; Muscle Contraction; Muscle, Smooth; Neural Inhibition; Neurons; Nitric Oxide; omega-N-Methylarginine; Radioimmunoassay; Rats; Rats, Wistar; Tetrodotoxin | 1993 |
Acetylcholine-induced relaxation in bovine isolated mesenteric arteries is suppressed by polymorphonuclear leukocytes.
Topics: Acetylcholine; Animals; Arginine; Catalase; Cattle; Endothelium, Vascular; Free Radical Scavengers; In Vitro Techniques; Indomethacin; Mesenteric Arteries; Muscle Relaxation; Muscle, Smooth, Vascular; Neutrophils; Nitroprusside; omega-N-Methylarginine; Superoxide Dismutase; Superoxides | 1993 |
Role of nitric oxide as an inhibitory neurotransmitter in the canine pyloric sphincter.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Arginine; Cyclic GMP; Dogs; Duodenum; Electric Stimulation; Female; Gastric Mucosa; In Vitro Techniques; Intercellular Junctions; Intestinal Mucosa; Male; Membrane Potentials; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Oxyhemoglobins; Phentolamine; Propranolol; Purinones; Pylorus; Stomach; Tetrodotoxin | 1993 |
Nitric oxide promotes DNA synthesis and cyclic GMP formation in endothelial cells from postcapillary venules.
Topics: Animals; Arginine; Cattle; Cells, Cultured; Coronary Vessels; Cyclic GMP; DNA; DNA Replication; Endothelium, Vascular; Fibroblast Growth Factor 2; Isosorbide Dinitrate; Kinetics; Nitric Oxide; Nitroglycerin; Nitroprusside; omega-N-Methylarginine; Thymidine; Venules | 1993 |
Evidence for altered platelet nitric oxide synthesis in essential hypertension.
Topics: Adult; Aged; Arginine; Blood Platelets; Collagen; Female; Humans; Hypertension; In Vitro Techniques; Male; Middle Aged; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Platelet Aggregation | 1993 |
Nitric oxide mediates interleukin-1-induced prostaglandin E2 production by vascular smooth muscle cells.
Topics: Animals; Aorta; Arginine; Cells, Cultured; Cyclic GMP; Dinoprostone; Humans; Interleukin-1; Kinetics; Muscle, Smooth, Vascular; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Rats; Recombinant Proteins; Superoxide Dismutase; Time Factors | 1993 |
Evidence of L-arginine/nitric oxide pathway in endothelium and smooth muscle of human internal mammary artery.
Topics: Acetylcholine; Aged; Arginine; Calcimycin; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Humans; In Vitro Techniques; Kinetics; Male; Mammary Arteries; Middle Aged; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; omega-N-Methylarginine | 1993 |
Pharmacological action of (-)-(2S,3aR,7aS)-1-[(S)-N-[(S)-1-carbonyl-3- phenylpropyl]alanyl]hexahydro-2-indolinecarboxylic acid (trandolaprilat) in isolated smooth muscle preparations.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Arginine; Bradykinin; Enalaprilat; Endothelium, Vascular; Guinea Pigs; Ileum; In Vitro Techniques; Indoles; Male; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; omega-N-Methylarginine; Rats; Rats, Wistar | 1993 |
Endothelium-dependent vasorelaxing activity of wine and other grape products.
Topics: Animals; Aorta; Arginine; Cyclic GMP; Endothelium, Vascular; Fruit; In Vitro Techniques; Male; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Plant Extracts; Rats; Rats, Sprague-Dawley; Vasodilation; Wine | 1993 |
Insulin attenuates agonist-mediated calcium mobilization in cultured rat vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Arginine; Calcium; Cells, Cultured; Cyclic GMP; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Insulin; Male; Muscle, Smooth, Vascular; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin | 1993 |
IL-6 down-modulates the cytokine-enhanced antileishmanial activity in human macrophages.
Topics: Animals; Arginine; Cells, Cultured; Cytokines; Down-Regulation; Humans; Interferon-gamma; Interleukin-3; Interleukin-6; Leishmania; Macrophages; Nitric Oxide; omega-N-Methylarginine; Superoxides; Tumor Necrosis Factor-alpha | 1993 |
Flavone acetic acid and 5,6-dimethylxanthenone-4-acetic acid: relationship between plasma nitrate elevation and the induction of tumour necrosis.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Arginine; Canavanine; Colonic Neoplasms; Flavonoids; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Necrosis; Nitrates; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Xanthenes; Xanthones | 1993 |
The effect of endothelins on nitric oxide and prostacyclin production from human umbilical vein, porcine aorta and bovine carotid artery endothelial cells in culture.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aorta; Arginine; Bradykinin; Carotid Arteries; Cattle; Cells, Cultured; Cyclic GMP; Endothelins; Endothelium, Vascular; Epoprostenol; Female; Hemoglobins; Histamine; Humans; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Pregnancy; Swine; Umbilical Veins | 1993 |
Nitric oxide synthesis inhibition induces leukocyte adhesion via superoxide and mast cells.
Topics: Animals; Arginine; Cell Adhesion; Cell Degranulation; Cells, Cultured; Humans; Leukocytes; Male; Mast Cells; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Superoxides | 1993 |
Effects of psychosocial stress on endothelium-mediated dilation of atherosclerotic arteries in cynomolgus monkeys.
Topics: Acetylcholine; Animals; Arginine; Arteriosclerosis; Calcimycin; Diet, Atherogenic; Dose-Response Relationship, Drug; Iliac Artery; In Vitro Techniques; Indomethacin; Macaca fascicularis; Male; Muscle, Smooth, Vascular; Nitroprusside; omega-N-Methylarginine; Social Behavior; Stress, Psychological; Vasodilation | 1993 |
Arginine feeding modifies cyclosporine nephrotoxicity in rats.
Topics: Administration, Oral; Angiotensin II; Animals; Arginine; Capillaries; Cyclosporine; Glomerular Filtration Rate; Hydrostatic Pressure; Kidney; Kidney Glomerulus; Male; Nephrons; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Wistar; Regional Blood Flow; Vascular Resistance | 1993 |
Heparin regulates endothelin production through endothelium-derived nitric oxide in human endothelial cells.
Topics: Analysis of Variance; Arginine; Blotting, Northern; Cells, Cultured; Cyclic GMP; Dactinomycin; Endothelins; Endothelium, Vascular; Heparin; Humans; Kinetics; Nitric Oxide; omega-N-Methylarginine; RNA, Messenger; Thrombin; Time Factors; Umbilical Veins | 1993 |
A single exogenous stimulus activates resident rat macrophages for nitric oxide production and tumor cytotoxicity.
Topics: Animals; Arginine; Cytotoxicity, Immunologic; Female; Humans; Interferon-gamma; Leukemia, Basophilic, Acute; Lipopolysaccharides; Macrophage Activation; Macrophages, Alveolar; Mast-Cell Sarcoma; Mice; Mice, Inbred DBA; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Rats, Wistar; Recombinant Proteins; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1993 |
Nitric oxide is not involved in the effects induced by non-adrenergic non-cholinergic stimulation and calcitonin gene-related peptide in the rat mesenteric vascular bed.
Topics: Acetylcholine; Animals; Arginine; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Guanethidine; Mesentery; Methoxamine; Methylene Blue; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Perfusion; Rats; Tetrodotoxin; Vasodilation | 1993 |
Coexistence of heterogeneous populations of Toxoplasma gondii parasites within parasitophorous vacuoles of murine macrophages as revealed by a bradyzoite-specific monoclonal antibody.
Topics: Animals; Antibodies, Monoclonal; Antigens, Protozoan; Arginine; Bone Marrow Cells; Cells, Cultured; Interferon-gamma; Macrophage Activation; Macrophages; Mice; omega-N-Methylarginine; Toxoplasma; Vacuoles | 1993 |
Neutralization of gamma interferon and tumor necrosis factor alpha blocks in vivo synthesis of nitrogen oxides from L-arginine and protection against Francisella tularensis infection in Mycobacterium bovis BCG-treated mice.
Topics: Animals; Antibodies, Monoclonal; Arginine; Interferon-gamma; Macrophage Activation; Male; Mice; Mice, Inbred C3H; Mycobacterium bovis; Nitric Oxide; omega-N-Methylarginine; Specific Pathogen-Free Organisms; Tularemia; Tumor Necrosis Factor-alpha | 1993 |
Vasomotor responses of canine coronary arterial rings to NG-monomethyl-L-arginine and N omega nitro L-arginine methyl ester.
Topics: Animals; Aorta, Abdominal; Arginine; Biotransformation; Coronary Vessels; Cycloheximide; Dogs; Drug Interactions; Endothelium, Vascular; Female; In Vitro Techniques; Indomethacin; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Rats; Vasomotor System | 1993 |
Nitric oxide mediates inhibitory nerve input in human and canine jejunum.
Topics: Animals; Arginine; Dogs; Electric Stimulation; Female; Humans; In Vitro Techniques; Jejunum; Male; Membrane Potentials; Muscle, Smooth; Neural Inhibition; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Species Specificity | 1993 |
Differential mechanisms of intracellular killing of Mycobacterium avium and Listeria monocytogenes by activated human and murine macrophages. The role of nitric oxide.
Topics: Animals; Arginase; Arginine; Cells, Cultured; Humans; Interferon-gamma; Listeria monocytogenes; Macrophage Activation; Macrophages; Mice; Mycobacterium avium; Nitric Oxide; omega-N-Methylarginine; Tumor Necrosis Factor-alpha | 1993 |
Studies on the glomerular microcirculatory actions of manidipine and its modulation of the systemic and renal effects of endothelin.
Topics: Animals; Arginine; Calcium Channel Blockers; Dihydropyridines; Drug Interactions; Endothelins; Glomerular Filtration Rate; Hemodynamics; Kidney Glomerulus; Male; Microcirculation; Nitric Oxide; Nitrobenzenes; omega-N-Methylarginine; Piperazines; Rats; Rats, Wistar; Vasodilation; Verapamil | 1993 |
Inhibition of nitric oxide formation in the nucleus tractus solitarius increases renal sympathetic nerve activity in rabbits.
Topics: Animals; Arginine; Arteries; Blood Pressure; Cerebellum; Denervation; Heart Rate; Kidney; Male; Nitric Oxide; omega-N-Methylarginine; Pressoreceptors; Rabbits; Sympathetic Nervous System | 1993 |
Coronary venular responses to flow and pressure.
Topics: Animals; Arginine; Blood Flow Velocity; Blood Pressure; Coronary Vessels; Endothelium, Vascular; Female; Male; omega-N-Methylarginine; Swine; Vasodilation; Venules | 1993 |
A 1-hour pulse with IL-1 beta induces formation of nitric oxide and inhibits insulin secretion by rat islets of Langerhans: evidence for a tyrosine kinase signaling mechanism.
Topics: Animals; Arginine; Cells, Cultured; Humans; Insulin; Insulin Secretion; Interleukin-1; Islets of Langerhans; Male; Nitric Oxide; omega-N-Methylarginine; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Signal Transduction | 1993 |
Endogenous nitric oxide inhibits the synthesis of cyclooxygenase products and interleukin-6 by rat Kupffer cells.
Topics: Animals; Arginine; Cell Survival; Cells, Cultured; Cyclooxygenase Inhibitors; Dinoprostone; Interferon-gamma; Interleukin-1; Interleukin-6; Kinetics; Kupffer Cells; Lipopolysaccharides; Male; Nitric Oxide; omega-N-Methylarginine; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Thromboxane B2; Tumor Necrosis Factor-alpha | 1993 |
Locally produced EDRF controls preglomerular resistance and ultrafiltration coefficient.
Topics: Animals; Arginine; Glomerular Filtration Rate; Hemodynamics; Kidney Glomerulus; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Renal Circulation; Vascular Resistance | 1993 |
Endothelium-dependent response of human internal mammary artery to hypoxia.
Topics: 6-Ketoprostaglandin F1 alpha; Arginine; Endothelium, Vascular; Humans; Hypoxia; Indomethacin; Mammary Arteries; Norepinephrine; omega-N-Methylarginine; Vasoconstriction; Vasodilation | 1993 |
Effect of arginine analogues on hemodynamic responses in conscious rats.
Topics: Animals; Arginine; Blood Pressure; Drug Synergism; Nitroarginine; omega-N-Methylarginine; Rats; Vasoconstrictor Agents | 1993 |
Neurogenic and non-neurogenic mechanisms of plasma extravasation in the rat.
Topics: Animals; Arginine; Blood Physiological Phenomena; Bradykinin; Dose-Response Relationship, Drug; Joints; Male; Models, Biological; omega-N-Methylarginine; Oxidopamine; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Sympathectomy, Chemical; Time Factors | 1993 |
Nitric oxide-dependent and -independent neurogenic relaxation of isolated dog urethra.
Topics: Animals; Arginine; Autonomic Nervous System; Dogs; Electric Stimulation; Electrodes; Female; Histamine; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Urethra; Vasoactive Intestinal Peptide | 1993 |
Steroid hormones inhibit induction of spontaneous nitric oxide production in cultured hepatocytes without changes in arginase activity or urea production.
Topics: Animals; Arginase; Arginine; Cells, Cultured; Cycloheximide; Dactinomycin; Dexamethasone; Estradiol; Glucocorticoids; Hormones; Kinetics; Liver; Mineralocorticoids; Nitric Oxide; omega-N-Methylarginine; Progesterone; Rats; Steroids; Urea | 1993 |
Nitric oxide production by mouse sponge matrix allograft-infiltrating cells. Comparison with the rat species.
Topics: Animals; Arginine; Cell Division; Extracellular Matrix; Female; Lymphocytes; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Nitric Oxide; omega-N-Methylarginine; Porifera; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Species Specificity; T-Lymphocytes, Cytotoxic; Transplantation, Homologous | 1993 |
Role of renal interstitial hydrostatic pressure in natriuresis of systemic nitric oxide inhibition.
Topics: Animals; Arginine; Blood Pressure; Diuresis; Glomerular Filtration Rate; Hydrostatic Pressure; Kidney; Male; Natriuresis; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley | 1993 |
Endothelium-dependent contractions to oxygen-derived free radicals in the canine basilar artery.
Topics: Animals; Arginine; Basilar Artery; Cattle; Dogs; Endothelium, Vascular; Free Radicals; Hydrogen Peroxide; Indomethacin; Meclofenamic Acid; Muscle Contraction; Muscle, Smooth, Vascular; omega-N-Methylarginine; Oxygen; Prostaglandins; Superoxide Dismutase; Thromboxane B2; Xanthine; Xanthine Oxidase; Xanthines | 1993 |
NG-monomethyl-L-arginine paradoxically relaxes preconstricted canine intrapulmonary arteries.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arginine; Cyclooxygenase Inhibitors; Dinoprostone; Dogs; Endothelium, Vascular; Epoprostenol; Immunoenzyme Techniques; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Phenylephrine; Potassium Chloride; Pulmonary Artery; Serotonin; Vasodilation | 1993 |
Role of nitric oxide pathway in the protection against lethal endotoxemia afforded by low doses of lipopolysaccharide.
Topics: Animals; Arginine; Dose-Response Relationship, Drug; Lipopolysaccharides; Male; Mice; Mice, Inbred BALB C; Nitric Oxide; omega-N-Methylarginine; Sepsis; Tumor Necrosis Factor-alpha | 1993 |
Involvement of nitric oxide in the blastogenic response deficiency in splenocytes from spontaneously hypertensive rats.
Topics: Animals; Arginine; Concanavalin A; Hypertension; Interleukin-2; Lymphocyte Activation; Lymphocytes; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Spleen; Thymus Gland | 1993 |
Malaria antigen and cytokine-induced production of reactive nitrogen intermediates by murine macrophages: no relevance to the development of experimental cerebral malaria.
Topics: Animals; Antigens, Protozoan; Arginine; Cytokines; Female; Interferon-gamma; Macrophages; Malaria, Cerebral; Mice; Mice, Inbred BALB C; Mice, Inbred CBA; Nitrogen; omega-N-Methylarginine; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1993 |
Roles of endothelin-1 and nitric oxide in the mechanism for ethanol-induced vasoconstriction in rat liver.
Topics: Animals; Arginine; Blood Pressure; Endothelins; Ethanol; Immune Sera; Liver; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Vasoconstriction | 1993 |
Picolinic acid, a catabolite of L-tryptophan, is a costimulus for the induction of reactive nitrogen intermediate production in murine macrophages.
Topics: Animals; Arginine; Cell Line; Drug Synergism; Interferon-gamma; Interleukin-4; Macrophage Activation; Macrophages; Mice; Mice, Inbred C57BL; Nitrites; omega-N-Methylarginine; Picolinic Acids; RNA, Messenger; Tryptophan; Tumor Necrosis Factor-alpha | 1993 |
Role of nitric oxide in interleukin 2-induced corticotropin-releasing factor release from incubated hypothalami.
Topics: Animals; Arginine; Carbachol; Corticotropin-Releasing Hormone; Dose-Response Relationship, Drug; Hypothalamus, Middle; In Vitro Techniques; Interleukin-2; Interneurons; Kinetics; Male; Models, Neurological; Neurons; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Recombinant Proteins | 1993 |
Prostanoids promote pial arteriolar dilation and mask constriction to oxytocin in piglets.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Animals, Newborn; Arginine; Arterioles; Blood Pressure; Dinoprostone; Dose-Response Relationship, Drug; Drug Interactions; Indomethacin; Microscopy; omega-N-Methylarginine; Oxytocin; Pia Mater; Radioimmunoassay; Swine; Vasoconstriction; Vasodilation | 1993 |
Endothelium-derived relaxing factor inhibits norepinephrine contraction of fetal guinea pig arteries.
Topics: Animals; Arginine; Arteries; Carotid Arteries; Endothelium, Vascular; Epithelium; Female; Fetus; Guinea Pigs; Indomethacin; Methylene Blue; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Oxyhemoglobins; Phenylephrine; Pregnancy; Pulmonary Artery; Vasoconstriction | 1993 |
Spontaneous contractions of isolated bat wing venules are inhibited by luminal flow.
Topics: Adenosine Triphosphate; Animals; Arachidonic Acids; Arginine; Chiroptera; Endothelium, Vascular; Female; Indomethacin; Male; omega-N-Methylarginine; Regional Blood Flow; Superoxide Dismutase; Vasoconstriction; Venules; Wings, Animal | 1993 |
L-arginine analogues blunt prostaglandin-related dilation of arterioles.
Topics: Acetylcholine; Adenosine; Animals; Arachidonic Acids; Arginine; Arterioles; Blood Pressure; Dinoprostone; Dose-Response Relationship, Drug; Male; Nitric Oxide; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Prostaglandins; Rats; Rats, Wistar; Vasodilation | 1993 |
Inhibition of nitric oxide synthesis impairs autoregulation of local cerebral blood flow in the rat.
Topics: Animals; Arginine; Autoradiography; Blood Gas Analysis; Blood Pressure; Brain; Brain Chemistry; Cerebral Hemorrhage; Cerebrovascular Circulation; Hypotension; Injections, Intravenous; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Wistar; Vascular Resistance | 1993 |
Interleukin-4 and interleukin-10 inhibit nitric oxide-dependent macrophage killing of Candida albicans.
Topics: Animals; Arginine; Candida albicans; Dose-Response Relationship, Drug; Down-Regulation; Female; Interferon-gamma; Interleukin-10; Interleukin-4; Macrophages; Male; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Nitric Oxide; omega-N-Methylarginine; Recombinant Proteins | 1993 |
Sustained hypertension induced by orally administered nitro-L-arginine.
Topics: Administration, Oral; Animals; Arginine; Blood Pressure; Heart Rate; Male; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley | 1993 |
Muramyldipeptide and granulocyte-macrophage colony-stimulating factor enhance interferon-gamma-induced nitric oxide production by rat alveolar macrophages.
Topics: Acetylmuramyl-Alanyl-Isoglutamine; Animals; Arginine; Drug Synergism; Granulocyte-Macrophage Colony-Stimulating Factor; Interferon-gamma; Macrophages, Alveolar; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Wistar; Specific Pathogen-Free Organisms | 1993 |
Nitric oxide modulates the release of corticotropin-releasing hormone from the rat hypothalamus in vitro.
Topics: Animals; Arginine; Basal Metabolism; Corticotropin-Releasing Hormone; Hypothalamus; In Vitro Techniques; Interleukin-1; Male; Molsidomine; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Potassium Chloride; Rats; Rats, Wistar | 1993 |
Action of carbon dioxide on hypoxic pulmonary vasoconstriction in the rat lung: evidence against specific endothelium-derived relaxing factor-mediated vasodilation.
Topics: Angiotensin II; Animals; Arginine; Blood Gas Analysis; Carbon Dioxide; Constriction, Pathologic; Disease Models, Animal; Drug Evaluation, Preclinical; Hypercapnia; Hypoxia; Male; Nitric Oxide; omega-N-Methylarginine; Pulmonary Circulation; Pulmonary Wedge Pressure; Random Allocation; Rats; Rats, Wistar; Respiration, Artificial; Vascular Resistance | 1993 |
Endothelium-derived relaxing factor activity in rat lung during hypoxic pulmonary vascular remodeling.
Topics: Angiotensin II; Animals; Arginine; Hypoxia; In Vitro Techniques; Lung; Male; Nitric Oxide; omega-N-Methylarginine; Perfusion; Pulmonary Circulation; Rats; Rats, Wistar; Vasoconstriction | 1993 |
Abundant production of nitric oxide from murine macrophages by direct stimulation of tumor cells.
Topics: Animals; Arginine; Cell Death; Cells, Cultured; Cytotoxicity, Immunologic; Macrophages; Mice; Mice, Inbred DBA; Nitric Oxide; omega-N-Methylarginine; Tumor Cells, Cultured | 1993 |
Abnormal contractile function due to induction of nitric oxide synthesis in rat cardiac myocytes follows exposure to activated macrophage-conditioned medium.
Topics: Animals; Arginine; Cell Line; Cells, Cultured; Culture Media, Conditioned; Heart; Heart Ventricles; Kinetics; Lipopolysaccharides; Macrophage Activation; Macrophages, Alveolar; Male; Myocardial Contraction; Myocardium; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley | 1993 |
Role of endothelium-derived nitric oxide in the abnormal endothelium-dependent vascular relaxation of patients with essential hypertension.
Topics: Acetylcholine; Adult; Arginine; Blood Flow Velocity; Endothelium, Vascular; Female; Humans; Hypertension; Male; Middle Aged; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Regional Blood Flow; Vascular Resistance; Vasodilation | 1993 |
Transient cerebral vasodilatory effect of neuropeptide Y mediated by nitric oxide.
Topics: Animals; Arginine; Blood Pressure; Brain Chemistry; Carotid Arteries; Cats; Cerebrovascular Circulation; Female; Injections, Intra-Arterial; Male; Neuropeptide Y; Nitric Oxide; omega-N-Methylarginine; Oxygen Consumption; Vasodilation | 1993 |
Cytokine-mediated inactivation of malarial gametocytes is dependent on the presence of white blood cells and involves reactive nitrogen intermediates.
Topics: Animals; Anopheles; Antigens, Protozoan; Arginine; Cells, Cultured; Cytokines; Humans; Leukocytes, Mononuclear; Malaria; Nitric Oxide; omega-N-Methylarginine; Plasmodium falciparum; Plasmodium vivax | 1993 |
Effects of acetylcholine on spontaneous contractions in isolated bovine mesenteric lymphatics.
Topics: Acetylcholine; Animals; Arginine; Aspirin; Atropine; Cattle; Histological Techniques; In Vitro Techniques; Lymphatic System; Mesentery; omega-N-Methylarginine; Reference Values | 1993 |
A stable L-arginine-dependent relaxing factor released from cytotoxic-activated macrophages.
Topics: Animals; Aorta; Arginine; Cells, Cultured; Drug Stability; Macrophages; omega-N-Methylarginine; Rabbits; Stereoisomerism; Vasoconstriction; Vasodilator Agents | 1993 |
Mechanisms for altered endothelium-dependent vasorelaxation in isolated kidneys from experimental hypertensive rats.
Topics: Acetylcholine; Animals; Arginine; Desoxycorticosterone; Endothelium, Vascular; Glyburide; Hypertension; In Vitro Techniques; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar; Renal Circulation; Sodium Chloride; Vascular Resistance; Vasodilation | 1993 |
Endothelium-derived factors modulate contraction of bronchial smooth muscle.
Topics: Animals; Arginine; Bronchi; Dogs; Endothelium, Vascular; Female; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; omega-N-Methylarginine; Pulmonary Artery | 1993 |
Nitric oxide mediates vasoactive effects of endothelin-3 on rat mesenteric microvascular beds in vivo.
Topics: Animals; Arginine; Arterioles; Dose-Response Relationship, Drug; Drug Interactions; Endothelins; Hemodynamics; Male; Mesenteric Arteries; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Wistar; Time Factors; Vasoconstriction | 1993 |
Pulmonary thromboembolism-induced alterations in nitric oxide release from rat circulating neutrophils.
Topics: Adenosine Deaminase; Animals; Arginine; Haplorhini; Hemoglobins; Hydrogen-Ion Concentration; Male; Methylene Blue; Neutrophils; Nitric Oxide; omega-N-Methylarginine; Platelet Aggregation; Pulmonary Embolism; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 1993 |
Relaxin inhibits histamine release from mast cells: involvement of nitric oxide production.
Topics: Animals; Arginine; Calcimycin; Enzyme Inhibitors; Exocytosis; Histamine Release; Mast Cells; Mesentery; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Relaxin; Vasodilation | 1995 |
Inhibition of nitric oxide synthase attenuates primed microvascular permeability in the in vivo microcirculation.
Topics: Animals; Arginine; Capillary Permeability; Cheek; Cricetinae; Cromolyn Sodium; Dextrans; Enzyme Inhibitors; Fluorescein-5-isothiocyanate; Histamine; Inflammation; Macrophage-1 Antigen; Male; Mast Cells; Mesocricetus; Microcirculation; Microscopy, Video; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Activating Factor | 1995 |
Direct modulation of enterocyte growth by activated macrophages.
Topics: Animals; Arginine; Celiac Disease; Cell Division; Cell Line; Indomethacin; Interferon-gamma; Intestinal Mucosa; Intestine, Small; Lipopolysaccharides; Macrophage Activation; Macrophages, Peritoneal; Nitric Oxide; omega-N-Methylarginine; Penicillamine; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Stem Cells; Tumor Necrosis Factor-alpha | 1995 |
Stimulation of glyceraldehyde-3-phosphate dehydrogenase mRNA levels by endogenous nitric oxide in cytokine-activated endothelium.
Topics: Animals; Arginine; Cells, Cultured; Endothelium, Vascular; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycolysis; Humans; Interferon-gamma; Mice; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Recombinant Proteins; RNA, Messenger; Tumor Necrosis Factor-alpha | 1995 |
Mechanism of bradykinin-induced cyclic GMP accumulation in bovine tracheal smooth muscle.
Topics: Animals; Arginine; Bradykinin; Calcium; Cattle; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Immunohistochemistry; In Vitro Techniques; Methylene Blue; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Pyrogallol; Superoxide Dismutase; Trachea | 1995 |
Regional differences in cerebral vasomotor control by nitric oxide.
Topics: Animals; Arginine; Arterioles; Cerebral Arteries; Cerebrovascular Circulation; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Hydrogen-Ion Concentration; Male; Microcirculation; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats | 1995 |
Capillary reperfusion after L-arginine, L-NMMA, and L-NNA treatment in cheek pouch microvasculature.
Topics: Animals; Arginine; Capillary Permeability; Cheek; Cricetinae; Enzyme Inhibitors; Ischemia; Male; Mesocricetus; Microcirculation; Microscopy, Fluorescence; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Reperfusion | 1995 |
Platelet activating factor modulates microvascular permeability through nitric oxide synthesis.
Topics: Animals; Arginine; Capillary Permeability; Cheek; Cricetinae; Male; Mesocricetus; Microcirculation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Activating Factor; Signal Transduction | 1995 |
Evidence that the L-arginine pathway plays a role in the regulation of pumping activity in bovine mesenteric lymphatic vessels.
Topics: Animals; Arginine; Cattle; Enzyme Inhibitors; Lymphatic System; Mesentery; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Oxyhemoglobins; Signal Transduction; Vasoconstriction | 1995 |
Production of nitric oxide (NO) is not essential for protection against acute Toxoplasma gondii infection in IRF-1-/- mice.
Topics: Animals; Arginine; CD4-Positive T-Lymphocytes; DNA-Binding Proteins; Female; Genetic Predisposition to Disease; Immunologic Factors; Interferon Regulatory Factor-1; Interferon-gamma; Interleukin-10; Interleukin-12; Lymphocyte Activation; Lymphocyte Depletion; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phosphoproteins; T-Lymphocyte Subsets; Toxoplasma; Toxoplasmosis, Animal; Transforming Growth Factor beta | 1996 |
Degradation of bovine cartilage proteoglycan in vitro is enhanced by inhibition of nitric oxide synthase.
Topics: Animals; Arginine; Cartilage; Cattle; Enzyme Inhibitors; Glycosaminoglycans; In Vitro Techniques; Indicators and Reagents; Interleukin-1; Metalloendopeptidases; Nitric Oxide Synthase; omega-N-Methylarginine; Phenylalanine; Protease Inhibitors; Proteoglycans; Thiophenes | 1995 |
Modulation of chondrocyte proteoglycan synthesis by endogeneously produced nitric oxide.
Topics: Animals; Arginine; Autoradiography; Cartilage, Articular; Dinoprostone; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; In Vitro Techniques; Interleukin-1; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Penicillamine; Proteoglycans; Rabbits; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents | 1995 |
Physical training improves endothelial function in patients with chronic heart failure.
Topics: Adult; Arginine; Chronic Disease; Endothelium, Vascular; Female; Forearm; Heart Failure; Humans; Male; Middle Aged; Nitroprusside; omega-N-Methylarginine; Physical Education and Training; Regional Blood Flow | 1996 |
Role of nitric oxide in the local regulation of pulmonary vascular resistance in humans.
Topics: Acetylcholine; Adult; Aged; Arginine; Female; Humans; Male; Middle Aged; Nitric Oxide; omega-N-Methylarginine; Pulmonary Circulation; Vascular Resistance; Vasodilation | 1996 |
Enhancement of platelet deposition by cross-linked hemoglobin in a rat carotid endarterectomy model.
Topics: Animals; Arginine; Aspirin; Blood Platelets; Endarterectomy; Hemodynamics; Hemoglobins; Humans; Male; Nitric Oxide; omega-N-Methylarginine; Platelet Count; Rats; Rats, Sprague-Dawley | 1996 |
The effect of nitric oxide synthase inhibition on portal pressure and azygos blood flow in patients with cirrhosis.
Topics: Adult; Aged; Aged, 80 and over; Arginine; Enzyme Inhibitors; Female; Humans; Infusions, Intravenous; Liver Cirrhosis; Male; Middle Aged; Nitric Oxide Synthase; omega-N-Methylarginine; Portal Pressure; Splanchnic Circulation; Thermography | 1995 |
Flow-induced dilation in newborn intestine.
Topics: Animals; Animals, Newborn; Arginine; Hemodynamics; In Vitro Techniques; Intestines; Mesenteric Arteries; omega-N-Methylarginine; Perfusion; Phenylephrine; Regional Blood Flow; Rheology; Swine; Vasodilation | 1995 |
The insulin secretory response to intravenous glucose in the rat is independent of NO formation.
Topics: Animals; Arginine; Blood Glucose; Blood Pressure; Enzyme Inhibitors; Glucose; Infusions, Intravenous; Insulin; Insulin Secretion; Islets of Langerhans; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Wistar | 1995 |
Interleukin-1 enhances pancreatic islet arachidonic acid 12-lipoxygenase product generation by increasing substrate availability through a nitric oxide-dependent mechanism.
Topics: Animals; Arachidonate 12-Lipoxygenase; Arginine; Base Sequence; Cells, Cultured; Enzyme Inhibitors; Interleukin-1; Islets of Langerhans; Male; Mass Spectrometry; Molecular Sequence Data; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substrate Specificity | 1996 |
Flow-mediated vasodilation of human epicardial coronary arteries: effect of inhibition of nitric oxide synthesis.
Topics: Acetylcholine; Adenosine; Arginine; Blood Flow Velocity; Cardiac Catheterization; Coronary Angiography; Coronary Circulation; Coronary Vessels; Enzyme Inhibitors; Female; Humans; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Vasodilation; Vasodilator Agents | 1996 |
Effect of diadenosine phosphates on human umbilical vessels: novel platelet-derived vasoconstrictors.
Topics: Arginine; Blood Platelets; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle, Smooth, Vascular; omega-N-Methylarginine; Theophylline; Umbilical Arteries; Vasoconstrictor Agents | 1995 |
Nitric oxide and peripheral adrenergic neuromodulation.
Topics: Animals; Antihypertensive Agents; Arginine; Electric Stimulation; Enzyme Inhibitors; Guinea Pigs; Heart; In Vitro Techniques; Male; Mesenteric Arteries; Myocardial Reperfusion Injury; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Norepinephrine; omega-N-Methylarginine; Peripheral Nervous System; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Synaptic Transmission; Synaptosomes | 1995 |
The mechanisms of the renal effects of neutral endopeptidase inhibitor in rats.
Topics: Adrenergic beta-Antagonists; Animals; Arginine; Atrial Natriuretic Factor; Bradykinin; Cyclic GMP; Cyclohexanecarboxylic Acids; Kidney; Kinins; Male; Neprilysin; Nitric Oxide; omega-N-Methylarginine; Protease Inhibitors; Rats; Rats, Sprague-Dawley | 1995 |
Effect of interleukin-4 and interleukin-10 on leucocyte migration and nitric oxide production in the mouse.
Topics: Animals; Arginine; CD11 Antigens; Chemotaxis, Leukocyte; Enzyme Inhibitors; Interleukin-1; Interleukin-10; Interleukin-4; Interleukin-8; Lipopolysaccharides; Macrophages, Peritoneal; Male; Mice; Neutrophils; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Up-Regulation | 1995 |
Zonal differences in nitric oxide synthesis by bovine chondrocytes exposed to interleukin-1.
Topics: Animals; Arginine; Cartilage, Articular; Cattle; Enzyme Inhibitors; Female; In Vitro Techniques; Interleukin-1; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Proteoglycans | 1995 |
Impaired protein catabolism in Trypanosoma cruzi-infected macrophages: possible involvement in antigen presentation.
Topics: Animals; Antigen Presentation; Arginine; CD4-Positive T-Lymphocytes; Cell Culture Techniques; Cellular Senescence; Chagas Disease; DNA-Binding Proteins; Indomethacin; Interferon-gamma; Macrophages, Peritoneal; Male; Mice; Mice, Inbred BALB C; omega-N-Methylarginine; Peptide Fragments; Receptors, Interleukin-2; Recombinant Proteins; Repressor Proteins; Tumor Necrosis Factor-alpha; Viral Proteins; Viral Regulatory and Accessory Proteins | 1995 |
Role of nitric oxide in exercise hyperaemia during prolonged rhythmic handgripping in humans.
Topics: Acetylcholine; Adolescent; Adult; Arginine; Enzyme Inhibitors; Forearm; Hand Strength; Humans; Hyperemia; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Periodicity; Physical Exertion; Regional Blood Flow; Time Factors | 1995 |
[Role of nitric oxide in the regulation of the mechanical properties of peripheral muscular arteries in man].
Topics: Adult; Arginine; Compliance; Enzyme Inhibitors; Female; Hemodynamics; Humans; Male; Nitric Oxide; omega-N-Methylarginine; Radial Artery; Ultrasonography | 1995 |
[Hemodynamic effects of sub-chronic NO synthase inhibition in conscious dogs: role of EDRF/NO in muscular exertion].
Topics: Acetylcholine; Animals; Arginine; Consciousness; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hemodynamics; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Physical Exertion | 1995 |
Suppression of cytokine production in T helper type 2 cells by nitric oxide in comparison with T helper type 1 cells.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; CD4-Positive T-Lymphocytes; Cell Line; Cells, Cultured; Cytokines; DNA; DNA Replication; Drug Combinations; Enzyme Inhibitors; Female; Indomethacin; Interferon-gamma; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Spleen; Th1 Cells; Th2 Cells | 1995 |
Nitric oxide synthase inhibitors decrease human polymorphonuclear leukocyte luminol-dependent chemiluminescence.
Topics: Animals; Arginine; Enzyme Inhibitors; Humans; Luminescent Measurements; Luminol; Macrophages; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Nitrates; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Ornithine; Oxidation-Reduction; Oxyhemoglobins; Rats; Superoxide Dismutase; Superoxides | 1995 |
Evidence against a role of nitric oxide in the indirect negative inotropic-effect of M-cholinoceptor stimulation in human ventricular myocardium.
Topics: Arginine; Carbachol; Cyclic GMP; Humans; Isoproterenol; Myocardial Contraction; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Papillary Muscles; Receptors, Cholinergic | 1995 |
Nitric oxide mediates mitochondrial dysfunction in hepatoma cells induced by non-activated Kupffer cells: evidence implicating ICAM-1-dependent process.
Topics: Animals; Antibodies, Monoclonal; Arginine; Cell Adhesion; Coculture Techniques; Dexamethasone; Fluorescent Dyes; Intercellular Adhesion Molecule-1; Kupffer Cells; Liver Neoplasms, Experimental; Male; Microscopy, Fluorescence; Mitochondria, Liver; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Wistar; Rhodamine 123; Rhodamines; Tumor Cells, Cultured | 1995 |
Cardiovascular effects of nitric oxide in the brain stem nuclei of rats.
Topics: Animals; Arginine; Brain Stem; Cardiovascular Physiological Phenomena; Cardiovascular System; Enzyme Induction; Hemodynamics; Male; Medulla Oblongata; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Solitary Nucleus | 1996 |
Inhibition of local nitric oxide synthase increases homeostatic efficiency of tubuloglomerular feedback.
Topics: Absorption; Animals; Arginine; Feedback; Glomerular Filtration Rate; Homeostasis; Kidney Glomerulus; Kidney Tubules; Male; Nephrons; Nitric Oxide Synthase; omega-N-Methylarginine; Perfusion; Punctures; Rats; Rats, Wistar | 1995 |
Endotoxin-induced myocardial dysfunction: is there a role for nitric oxide?
Topics: Animals; Arginine; Enzyme Inhibitors; Guanidines; Guinea Pigs; Heart Atria; Immunoenzyme Techniques; Lipopolysaccharides; Male; Myocardial Contraction; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Shock, Septic | 1995 |
Regulation of energy metabolism by interleukin-1beta, but not by interleukin-6, is mediated by nitric oxide in primary cultured rat hepatocytes.
Topics: Adenine Nucleotides; Animals; Arginine; Cells, Cultured; Enzyme Inhibitors; Insulin; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Interleukin-6; Ketone Bodies; Lactates; Lactic Acid; Liver; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Oxidation-Reduction; Rats; Rats, Wistar; Recombinant Proteins; Sialoglycoproteins; Tumor Necrosis Factor-alpha | 1996 |
Relaxant effect of nitric oxide and prostacyclin on serotonin-induced vasocontraction of human umbilical artery.
Topics: Arginine; Drug Interactions; Enzyme Inhibitors; Epoprostenol; Female; Humans; Methylene Blue; Monoamine Oxidase Inhibitors; Nitric Oxide; omega-N-Methylarginine; Platelet Aggregation Inhibitors; Pregnancy; Receptors, Serotonin; Serotonin; Tranylcypromine; Umbilical Arteries; Vasoconstriction; Vasodilation | 1996 |
Nitric oxide relaxes rabbit corpus cavernosum smooth muscle via a potassium-conductive pathway.
Topics: Acetylcholine; Animals; Arginine; Cells, Cultured; Cyclic AMP; Enzyme Inhibitors; Kinetics; Male; Membrane Potentials; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Penis; Potassium; Potassium Channels; Rabbits; Tetraethylammonium; Tetraethylammonium Compounds; Time Factors; Vasodilator Agents | 1996 |
Interactive control of renal function by alpha 2-adrenergic system and nitric oxide: role of angiotensin II.
Topics: Angiotensin II; Animals; Arginine; Biphenyl Compounds; Hemodynamics; Imidazoles; Kidney; Losartan; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Tetrazoles | 1995 |
Enhancing effect of oxygen radical scavengers on murine macrophage anticryptococcal activity through production of nitric oxide.
Topics: Animals; Antibodies, Fungal; Arginine; Catalase; Cryptococcus neoformans; Enzyme Inhibitors; Female; Free Radical Scavengers; Interferon-gamma; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Nitric Oxide; Nitrogen Compounds; omega-N-Methylarginine; Reactive Oxygen Species; Superoxide Dismutase | 1996 |
Induction of nitric oxide and nitric oxide synthase mRNA by silica and lipopolysaccharide in PMA-primed THP-1 cells.
Topics: Allopurinol; Antimetabolites; Arginine; Cycloheximide; Dactinomycin; Enzyme Induction; Enzyme Inhibitors; Gene Expression Regulation, Leukemic; Humans; Leukemia, Monocytic, Acute; Lipopolysaccharides; Monocytes; Neoplasm Proteins; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Protein Synthesis Inhibitors; RNA, Messenger; Silicon Dioxide; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Xanthine Oxidase | 1996 |
Nitric oxide induced poly(ADP-ribose) polymerase cleavage in RAW 264.7 macrophage apoptosis is blocked by Bcl-2.
Topics: Animals; Apoptosis; Arginine; Cell Line; Chromatin; Glutathione; Interferon-gamma; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; Nitroso Compounds; omega-N-Methylarginine; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; S-Nitrosoglutathione; Spermine; Tumor Suppressor Protein p53 | 1996 |
Nitric oxide induces upregulation of Fas and apoptosis in vascular smooth muscle.
Topics: Animals; Apoptosis; Arginine; Cells, Cultured; Enzyme Inhibitors; fas Receptor; Humans; Interleukin-1; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Rats; Up-Regulation | 1996 |
Nitric oxide mediation of chemoregulation but not autoregulation of cerebral blood flow in primates.
Topics: Animals; Arginine; Cerebrovascular Circulation; Homeostasis; Hypercapnia; Macaca mulatta; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine | 1996 |
Tyrosine phosphorylation of inducible nitric oxide synthase: implications for potential post-translational regulation.
Topics: Animals; Arginine; Base Sequence; Calcium; Cell Line; DNA Primers; Enzyme Induction; Enzyme Inhibitors; Gene Expression; Interferon-gamma; Isoenzymes; Kinetics; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Molecular Sequence Data; Nitric Oxide Synthase; omega-N-Methylarginine; Phosphorylation; Phosphotyrosine; Polymerase Chain Reaction; Protein Processing, Post-Translational; Time Factors | 1996 |
Endogenous basal nitric oxide production does not control myocardial oxygen consumption or function.
Topics: Acetylcholine; Analysis of Variance; Animals; Arginine; Biomechanical Phenomena; Coronary Circulation; Cyclic GMP; Dogs; Enzyme Inhibitors; Hemodynamics; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Oxygen Consumption | 1996 |
Nitric oxide production in cells derived from the human joint.
Topics: Arginine; Cartilage, Articular; Cells, Cultured; Cytokines; Dexamethasone; Drug Combinations; Humans; Joints; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Osteoblasts; Synovial Fluid; Synovial Membrane; Tumor Necrosis Factor-alpha | 1996 |
N-monomethyl-arginine and nicotinamide prevent streptozotocin-induced double strand DNA break formation in pancreatic rat islets.
Topics: Animals; Arginine; Cell Survival; DNA Damage; Enzyme Inhibitors; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Male; Niacinamide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Wistar; Streptozocin | 1996 |
Contribution of sustained Ca2+ elevation for nitric oxide production in endothelial cells and subsequent modulation of Ca2+ transient in vascular smooth muscle cells in coculture.
Topics: Animals; Aorta; Arginine; Bradykinin; Calcium; Calcium-Transporting ATPases; Cattle; Cells, Cultured; Chelating Agents; Coculture Techniques; Endothelium, Vascular; Enzyme Inhibitors; Glyburide; Indomethacin; Ionomycin; Kinetics; Muscle, Smooth, Vascular; Nickel; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Terpenes; Thapsigargin; Time Factors | 1996 |
Nitric oxide inhibits viral replication in murine myocarditis.
Topics: Amino Acid Sequence; Animals; Antibodies; Arginine; Cell Line; Cells, Cultured; Coxsackievirus Infections; Enterovirus B, Human; Enzyme Induction; Enzyme Inhibitors; Immunohistochemistry; Isoenzymes; Macrophage Activation; Macrophages; Mice; Mice, Inbred Strains; Molecular Sequence Data; Myocarditis; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Peptide Fragments; Rabbits; Spleen; Transcription, Genetic; Virus Replication | 1996 |
Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone.
Topics: Acetylcholine; Angiotensin II; Animals; Antihypertensive Agents; Aorta; Arginine; Biphenyl Compounds; Calcimycin; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Hypertension; Imidazoles; In Vitro Techniques; Losartan; Male; Muscle Relaxation; Muscle Tonus; Muscle, Smooth, Vascular; NADH, NADPH Oxidoreductases; Nitric Oxide Synthase; Nitroglycerin; Norepinephrine; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Superoxides; Tetrazoles | 1996 |
Inhibitors of the proteasome pathway interfere with induction of nitric oxide synthase in macrophages by blocking activation of transcription factor NF-kappa B.
Topics: Amino Acid Sequence; Animals; Arginine; Base Sequence; Calpain; Cell Line; Cycloheximide; Cysteine Endopeptidases; DNA; Enzyme Induction; Lipopolysaccharides; Macrophage Activation; Macrophages, Alveolar; Molecular Sequence Data; Multienzyme Complexes; NF-kappa B; Nitric Oxide Synthase; Oligopeptides; omega-N-Methylarginine; Protease Inhibitors; Proteasome Endopeptidase Complex; Rats; RNA, Messenger | 1996 |
Glutamate-induced disruption of the blood-brain barrier in rats. Role of nitric oxide.
Topics: Animals; Arginine; Arterioles; Blood-Brain Barrier; Dextrans; Fluorescein-5-isothiocyanate; Glutamic Acid; Kinetics; Male; Microcirculation; Nitric Oxide; omega-N-Methylarginine; Penicillamine; Pia Mater; Rats; Rats, Inbred WF; Reference Values; S-Nitroso-N-Acetylpenicillamine; Time Factors; Vasodilator Agents | 1996 |
Nitric oxide and endothelins are effector agents of hyperacute vascular rejection.
Topics: Animals; Arginine; Dogs; Egtazic Acid; Endothelins; Enzyme Inhibitors; Graft Rejection; Kidney Transplantation; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Renal Circulation; Swine; Transplantation, Autologous; Transplantation, Heterologous | 1996 |
Effects of N(g)-methyl-L-arginine, an inhibitor of nitric oxide synthesis, on interleukin-2-induced capillary leakage and antitumor responses in healthy and tumor-bearing mice.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Arginine; Capillary Permeability; Cell Division; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Female; Interleukin-12; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Pleural Effusion; Pulmonary Edema | 1996 |
Murine epidermal Langerhans cells do not express inducible nitric oxide synthase.
Topics: Animals; Arginine; Enzyme Induction; Epidermal Cells; Epidermis; Female; Host-Parasite Interactions; Langerhans Cells; Leishmania major; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Penicillamine; Rats; RNA, Messenger; S-Nitroso-N-Acetylpenicillamine | 1996 |
Basal release of endothelium-derived nitric oxide at site of spasm in patients with variant angina.
Topics: Aged; Angina Pectoris, Variant; Arginine; Coronary Vasospasm; Coronary Vessels; Endothelium, Vascular; Enzyme Inhibitors; Female; Humans; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine | 1996 |
J774 murine macrophage-like cell interactions with Cryptococcus neoformans in the presence and absence of opsonins.
Topics: Animals; Antibodies, Fungal; Antibodies, Monoclonal; Arginine; Blood; Cell Line; Cryptococcus neoformans; Enzyme Inhibitors; Free Radical Scavengers; Macrophages; Mice; Mice, Inbred BALB C; Nitric Oxide Synthase; omega-N-Methylarginine; Opsonin Proteins; Phagocytosis; Polysaccharides | 1996 |
Differential regulation of intracellular signaling systems by sodium fluoride in rat glioma cells.
Topics: Animals; Arginine; Calcium; Chelating Agents; Cyclic GMP; Egtazic Acid; Enzyme Inhibitors; Glioma; omega-N-Methylarginine; Rats; Serotonin; Signal Transduction; Sodium Fluoride; Sulfonamides; Time Factors; Tumor Cells, Cultured; Vasodilator Agents | 1996 |
Evidence that epithelium-derived relaxing factor released by bradykinin in the guinea pig trachea is nitric oxide.
Topics: Adrenergic beta-Antagonists; Animals; Arginine; Bradykinin; Culture Techniques; Cyclic GMP; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelium; Guinea Pigs; Indomethacin; Isomerism; Male; Muscle Contraction; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Trachea | 1996 |
Apoptotic death of human leukemic cells induced by vascular cells expressing nitric oxide synthase in response to gamma-interferon and tumor necrosis factor-alpha.
Topics: Animals; Aorta; Apoptosis; Arginine; Cell Line; Cell Survival; Cells, Cultured; Coculture Techniques; DNA, Neoplasm; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Flow Cytometry; Gene Expression; Humans; Interferon-gamma; Isoenzymes; Leukemia, Erythroblastic, Acute; Mitochondria; Muscle, Smooth, Vascular; Nitric Oxide Synthase; omega-N-Methylarginine; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1996 |
Interleukin 1 alpha and gamma-interferon induction of nitric oxide production from murine tumor-derived endothelial cells.
Topics: Animals; Arginine; Drug Interactions; Endothelium, Vascular; Enzyme Inhibitors; Female; Fibrosarcoma; Interferon-gamma; Interleukin-1; Kinetics; Male; Mice; Mice, Inbred C3H; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Recombinant Proteins; Time Factors | 1996 |
Differential sensitivity of venular and arteriolar alpha-adrenergic receptor constriction to inhibition by hypoxia. Role of receptor subtype and coupling heterogeneity.
Topics: Animals; Arginine; Arterioles; Calcium Channels; Cell Hypoxia; Male; omega-N-Methylarginine; Potassium Channels; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Vasoconstriction; Venules | 1996 |
Nitric oxide synthase (NOS3)-mediated cholinergic modulation of Ca2+ current in adult rabbit atrioventricular nodal cells.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Action Potentials; Animals; Arginine; Atrioventricular Node; Calcium Channels; Carbachol; Cyclic GMP; Immunohistochemistry; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rabbits; Receptors, Muscarinic | 1996 |
The insulin-induced increase of guanosine-3',5'-cyclic monophosphate in human platelets is mediated by nitric oxide.
Topics: Adult; Analysis of Variance; Arginine; Blood Platelets; Cyclic GMP; Enzyme Inhibitors; Female; Humans; Insulin; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Recombinant Proteins | 1996 |
NG-monomethyl-L-arginine inhibits the blood flow but not the insulin-like response of forearm muscle to IGF- I: possible role of nitric oxide in muscle protein synthesis.
Topics: Adult; Arginine; Female; Forearm; Humans; Insulin-Like Growth Factor I; Lactates; Lactic Acid; Male; Muscle Proteins; Muscle, Skeletal; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Oxygen Consumption; Phenylalanine; Regional Blood Flow | 1996 |
Gender differences in atherosclerosis: possible role of nitric oxide.
Topics: Acetylcholine; Animals; Arginine; Arteriosclerosis; Calcimycin; Estradiol; Estrone; Female; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Rabbits; Sex Factors; Vasodilation | 1995 |
Pathogenesis of influenza virus-induced pneumonia: involvement of both nitric oxide and oxygen radicals.
Topics: Animals; Arginine; Electron Spin Resonance Spectroscopy; Enzyme Induction; Enzyme Inhibitors; Free Radicals; Influenza A virus; Interferon-gamma; Lung; Male; Mice; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Pneumonia, Viral; Reactive Oxygen Species; Superoxides | 1996 |
Nitric oxide: a modulator for the epidermal growth factor receptor expression in developing ovarian granulosa cells.
Topics: Animals; Arginine; Cells, Cultured; Cyclic AMP; Cyclic GMP; Diethylstilbestrol; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Female; Follicle Stimulating Hormone; Granulosa Cells; Kinetics; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Rats; Rats, Wistar; Sexual Maturation | 1996 |
Cardiac and regional haemodynamics, inducible nitric oxide synthase (NOS) activity, and the effects of NOS inhibitors in conscious, endotoxaemic rats.
Topics: Animals; Arginine; Cardiac Output; Disease Models, Animal; Enzyme Induction; Hemodynamics; Hypotension; Lipopolysaccharides; Lung; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Reproducibility of Results; Stroke Volume; Tachycardia | 1995 |
Endothelial nitric oxide production and insulin sensitivity. A physiological link with implications for pathogenesis of cardiovascular disease.
Topics: Acetylcholine; Adult; Arginine; Blood Pressure; Body Mass Index; Cardiovascular Diseases; Endothelium, Vascular; Humans; Insulin; Insulin Resistance; Male; Nitric Acid; Nitric Oxide Synthase; Nitroprusside; Norepinephrine; omega-N-Methylarginine; Plethysmography, Impedance; Vasodilation | 1996 |
Cigarette smoking potentiates endothelial dysfunction of forearm resistance vessels in patients with hypercholesterolemia. Role of oxidized LDL.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Arginine; Arteriosclerosis; Autoantibodies; Cardiovascular Diseases; Endothelium, Vascular; Female; Forearm; Humans; Hypercholesterolemia; Lipid Peroxidation; Lipoproteins, LDL; Male; Middle Aged; Muscle, Smooth, Vascular; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Oxidation-Reduction; Phentolamine; Risk Factors; Smoking; Vascular Resistance; Vasodilation; Vasodilator Agents; Vasomotor System | 1996 |
Evaluation of the relative contribution of nitric oxide and peroxynitrite to the suppression of mitochondrial respiration in immunostimulated macrophages using a manganese mesoporphyrin superoxide dismutase mimetic and peroxynitrite scavenger.
Topics: Animals; Aorta, Thoracic; Arginine; Cell Line; Diethylamines; Escherichia coli; Free Radical Scavengers; In Vitro Techniques; Kinetics; Lipopolysaccharides; Macrophages; Manganese; Metalloporphyrins; Mitochondria; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; omega-N-Methylarginine; Oxidation-Reduction; Oxygen Consumption; Penicillamine; Rabbits; S-Nitroso-N-Acetylpenicillamine; Superoxide Dismutase; Vasodilation | 1996 |
Adrenomedullin increases inducible nitric oxide synthase in rat vascular smooth muscle cells stimulated with interleukin-1.
Topics: Adrenomedullin; Animals; Arginine; Cells, Cultured; Cyclic AMP; Enzyme Inhibitors; Interleukin-1; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Peptides; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 1996 |
Spontaneously increased production of nitric oxide and aberrant expression of the inducible nitric oxide synthase in vivo in the transforming growth factor beta 1 null mouse.
Topics: Amino Acid Sequence; Animals; Arginine; Blotting, Northern; Enzyme Induction; Gene Expression; Genotype; Immunohistochemistry; Isoenzymes; Kidney; Mice; Mice, Knockout; Molecular Sequence Data; Myocardium; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Peptide Fragments; Polymerase Chain Reaction; Reference Values; RNA, Messenger; Transforming Growth Factor beta | 1996 |
Nitric oxide inhibition attenuates systemic hypotension produced by protamine.
Topics: Animals; Arginine; Blood Pressure; Cardiac Output; Cyclic GMP; Dogs; Endothelium, Vascular; Enzyme Inhibitors; Female; Hemodynamics; Heparin; Hypotension; In Vitro Techniques; Male; Methylene Blue; Models, Cardiovascular; Myocardial Contraction; Nitric Oxide; omega-N-Methylarginine; Protamines; Rabbits | 1996 |
Nitric oxide production by coronary conductance and resistance vessels in hypercholesterolemia patients.
Topics: Acetylcholine; Adult; Aged; Analysis of Variance; Arginine; Blood Flow Velocity; Coronary Angiography; Coronary Circulation; Coronary Vessels; Echocardiography, Doppler; Enzyme Inhibitors; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Vascular Resistance; Vasodilation | 1996 |
Regulation of the mouse inducible-type nitric oxide synthase gene promoter by interferon-gamma, bacterial lipopolysaccharide and NG-monomethyl-L-arginine.
Topics: Animals; Arginine; Base Sequence; Cell Line; Chloramphenicol O-Acetyltransferase; DNA Primers; Enzyme Induction; Enzyme Inhibitors; Escherichia coli; Gene Expression Regulation, Enzymologic; Interferon-gamma; Isoenzymes; Lipopolysaccharides; Macrophages; Mice; Molecular Sequence Data; Nitric Oxide Synthase; Oligonucleotides, Antisense; omega-N-Methylarginine; Promoter Regions, Genetic; Recombinant Proteins; RNA, Messenger; Transcription, Genetic; Transfection | 1996 |
A nitric oxide-sensitive electrode: requirement of lower oxygen concentration for detecting nitric oxide from the tissue.
Topics: Animals; Aorta, Thoracic; Arginine; Carbachol; Electrodes; Guinea Pigs; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Norepinephrine; omega-N-Methylarginine; Oxygen; Partial Pressure; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents | 1996 |
Human dermal fibroblasts produce nitric oxide and express both constitutive and inducible nitric oxide synthase isoforms.
Topics: Animals; Arginine; Base Sequence; DNA, Complementary; Enzyme Induction; Enzyme Inhibitors; Fibroblasts; Gene Expression; Humans; Immunohistochemistry; Interferon-gamma; Isoenzymes; Lipopolysaccharides; Molecular Sequence Data; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Recombinant Proteins; RNA, Messenger; Skin | 1996 |
Constitutive nitric oxide synthase is present in normal human keratinocytes.
Topics: Arginine; Calcium; Calmodulin; Canavanine; Cells, Cultured; Cytosol; Enzyme Inhibitors; Humans; Isoenzymes; Keratinocytes; Kinetics; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine | 1996 |
Transcriptional regulation of LDL receptor-related protein by IFN-gamma and the antagonistic activity of TGF-beta(1) in the RAW 264.7 macrophage-like cell line.
Topics: Animals; Antigens, CD; Arginine; Cell Line; Gene Expression Regulation; Humans; Interferon gamma Receptor; Interferon-gamma; Low Density Lipoprotein Receptor-Related Protein-1; Macrophages; Mice; omega-N-Methylarginine; Receptors, Immunologic; Receptors, Interferon; RNA, Messenger; Transcription, Genetic; Transforming Growth Factor beta | 1996 |
Endothelin-1 synthesis and receptor-mediated activity in porcine lymph vessels.
Topics: Analysis of Variance; Animals; Arginine; Bronchi; Endothelin Receptor Antagonists; Endothelins; Endothelium, Lymphatic; Enzyme Inhibitors; Immunohistochemistry; In Vitro Techniques; Lymphatic System; Mediastinum; Muscle Contraction; Muscle, Smooth; Nitric Oxide Synthase; Oligopeptides; omega-N-Methylarginine; Piperidines; Receptor, Endothelin A; Receptors, Endothelin; Swine; Trachea | 1996 |
Ca(2+)-mediated damage to rabbit gastric mucosal cells: modulation by nitric oxide.
Topics: Animals; Arginine; Calcimycin; Calcium; Cell Survival; Cytosol; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Free Radical Scavengers; Gastric Mucosa; Ionophores; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Oxidative Stress; Penicillamine; Rabbits; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents | 1995 |
Nitric oxide mediates the inhibitory action of platelet-activating factor on angiotensin II-induced renal vasoconstriction, in vivo.
Topics: Angiotensin II; Animals; Arginine; Blood Pressure; Enzyme Inhibitors; Kidney; Linear Models; Male; Nitric Oxide; omega-N-Methylarginine; Platelet Activating Factor; Rats; Rats, Wistar; Vasoconstriction | 1996 |
Nitric oxide mediates hepatic cytochrome P450 dysfunction induced by endotoxin.
Topics: Animals; Arginine; Cytochrome P-450 Enzyme Inhibitors; Guanidines; Lipopolysaccharides; Male; Microsomes, Liver; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley | 1996 |
Reversibility of inhibition of human type II nitric oxide synthase.
Topics: Adenosine Diphosphate; Animals; Arginine; Cell Line; Colonic Neoplasms; Enzyme Inhibitors; Humans; Isoenzymes; Isothiuronium; Kinetics; Macrophages; Mice; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Onium Compounds; Tumor Cells, Cultured | 1996 |
Platelet-activating factor augments lipopolysaccharide-induced nitric oxide formation by rat Kupffer cells.
Topics: Animals; Arginine; Biological Transport, Active; Cells, Cultured; Cyclic GMP; Cycloheximide; Dactinomycin; Drug Synergism; Enzyme Induction; Enzyme Inhibitors; Kinetics; Kupffer Cells; Lipopolysaccharides; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Activating Factor; Protein Synthesis Inhibitors; Rats; RNA, Messenger; Shock, Septic | 1996 |
Influence of nitric oxide on renal function in toxic acute renal failure in the rat.
Topics: Acute Kidney Injury; Animals; Arginine; Blood Pressure; Creatinine; Enzyme Inhibitors; Female; Glomerular Filtration Rate; Kidney; Models, Biological; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Reference Values; Renal Circulation; Sodium; Time Factors; Uranyl Nitrate; Urination | 1996 |
Localized administration of sodium nitroprusside enhances its protection against platelet aggregation in stenosed and injured coronary arteries.
Topics: Administration, Topical; Animals; Arginine; Coronary Circulation; Coronary Disease; Dogs; Endothelium, Vascular; Enzyme Inhibitors; Hemodynamics; Injections, Intravenous; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Pericardium; Platelet Aggregation; Platelet Aggregation Inhibitors; Time Factors; Vasodilator Agents | 1996 |
The multiple organ dysfunction syndrome caused by endotoxin in the rat: attenuation of liver dysfunction by inhibitors of nitric oxide synthase.
Topics: Animals; Arginine; beta-Aminoethyl Isothiourea; Cardiovascular Diseases; Chemical and Drug Induced Liver Injury; Enzyme Induction; Enzyme Inhibitors; Kidney Diseases; Lipopolysaccharides; Male; Multiple Organ Failure; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Wistar | 1995 |
Comparative effects of angiotensin II and its degradation products angiotensin III and angiotensin IV in rat aorta.
Topics: Angiotensin II; Angiotensin III; Animals; Aorta; Arginine; Endothelium, Vascular; Enzyme Inhibitors; In Vitro Techniques; Male; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Wistar; Tachyphylaxis; Vasoconstrictor Agents | 1995 |
Enhancement of the haemodynamic effects of NG-monomethyl-L-arginine by transforming growth factor-beta 1 in conscious, normal, but not endotoxaemic, rats.
Topics: Animals; Arginine; Drug Synergism; Enzyme Inhibitors; Hemodynamics; Indans; Infusions, Intravenous; Lipopolysaccharides; Male; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Reference Values; Sodium Chloride; Transforming Growth Factor beta | 1995 |
The ineffectiveness of the NO-cyclic GMP signaling pathway in the atrial myocardium.
Topics: Acetylcholine; Animals; Arginine; Atrial Function; Carbachol; Enzyme Inhibitors; Female; Guanosine Monophosphate; Guinea Pigs; Heart Atria; Humans; Male; Myocardial Contraction; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rabbits; Ranidae; Rats; Rats, Sprague-Dawley; Signal Transduction; Vasodilator Agents | 1995 |
Induction of L-arginine-dependent production of nitric oxide in bovine monocytes by interferon gamma and lipopolysaccharide.
Topics: Animals; Arginine; Cattle; Cells, Cultured; Enzyme Inhibitors; Female; Interferon-gamma; Kinetics; Lipopolysaccharides; Monocytes; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Recombinant Proteins; Time Factors | 1996 |
Nitric oxide mediates early dysfunction of rat and mouse islets after transplantation.
Topics: Animals; Arginine; Base Sequence; Enzyme Induction; Islets of Langerhans; Islets of Langerhans Transplantation; Leukocytes, Mononuclear; Liver; Male; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Nitrates; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Inbred Lew; Rats, Wistar; RNA, Messenger | 1996 |
Studies on nitric oxide free radicals generated from polymorphonuclear leukocytes (PMN) stimulated by phorbol myristate acetate (PMA).
Topics: Arginine; Cyclic N-Oxides; Enzyme Inhibitors; Free Radicals; Humans; Luminescent Measurements; Luminol; Neutrophils; Nitric Oxide; omega-N-Methylarginine; Spin Labels; Tetradecanoylphorbol Acetate; Xanthine; Xanthine Oxidase; Xanthines | 1996 |
Effects of three inhibitors of nitric oxide synthase on host resistance to bacterial infection.
Topics: Animals; Arginine; Disease Models, Animal; Enzyme Inhibitors; Escherichia coli Infections; Female; Mice; Mice, Inbred BALB C; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Ornithine; Prospective Studies; Random Allocation | 1996 |
Cardiac and regional hemodynamic interactions between halothane and nitric oxide synthase activity in dogs.
Topics: Anesthetics, Inhalation; Animals; Arginine; Dogs; Enzyme Inhibitors; Female; Halothane; Hemodynamics; Male; Nitric Oxide Synthase; omega-N-Methylarginine | 1996 |
Interleukin-12 gene-expression of macrophages is regulated by nitric oxide.
Topics: Animals; Arginine; Cell Line; Enzyme Inhibitors; Gene Expression Regulation; Interferon-gamma; Interleukin-12; Macrophage Activation; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Penicillamine; Rats; Recombinant Proteins; RNA, Messenger; S-Nitroso-N-Acetylpenicillamine; Transcription, Genetic | 1996 |
Superficial hand vein responses to NG-monomethyl-L-arginine in post-partum and non-pregnant women.
Topics: Adult; Arginine; Female; Hand; Humans; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Postpartum Period; Pregnancy; Time Factors; Vasoconstriction; Vasodilation; Veins | 1996 |
Peroxynitrite formation from activated human leukocytes.
Topics: Animals; Arginine; Enzyme Inhibitors; Humans; Luminescent Measurements; Macrophages, Alveolar; Neutrophils; Nitrates; Nitrites; Nitrophenols; omega-N-Methylarginine; Peroxidase; Phenylacetates; Rats; Superoxides; Tetradecanoylphorbol Acetate | 1996 |
Interferon-gamma-dependent expression of inducible nitric oxide synthase, interleukin-12, and interferon-gamma-inducing factor in macrophages elicited by allografted tumor cells.
Topics: Animals; Apoptosis; Arginine; Base Sequence; Cell Line; Cell Survival; Cells, Cultured; Cytokines; DNA; DNA Primers; Enzyme Induction; Enzyme Inhibitors; Fibrosarcoma; Gene Expression; Interferon-gamma; Interleukin-12; Interleukin-18; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Molecular Sequence Data; Mycobacterium bovis; Neoplasm Transplantation; Nitric Oxide Synthase; omega-N-Methylarginine; Polymerase Chain Reaction; Time Factors; Transplantation, Homologous | 1996 |
Interferon-gamma suppresses T-cell proliferation to mitogen via the nitric oxide pathway during experimental acute graft-versus-host disease.
Topics: Acute Disease; Animals; Arginine; Bone Marrow Transplantation; Concanavalin A; Enzyme Activation; Enzyme Inhibitors; Female; Graft vs Host Disease; Interferon-gamma; Interleukin-4; Isoantigens; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Mitogens; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Radiation Chimera; Spleen; T-Lymphocytes | 1996 |
Nitric oxide synthase inhibition versus norepinephrine for the treatment of hyperdynamic sepsis in sheep.
Topics: Animals; Arginine; Disease Models, Animal; Drug Evaluation, Preclinical; Enzyme Inhibitors; Female; Hemodynamics; Nitric Oxide Synthase; Norepinephrine; omega-N-Methylarginine; Oxygen Consumption; Prospective Studies; Sepsis; Sheep; Time Factors; Vasoconstrictor Agents | 1996 |
Role in nitric oxide in Kupffer cell-mediated hepatoma cell cytotoxicity in vitro and ex vivo.
Topics: Animals; Arginine; Cell Survival; Cells, Cultured; Coculture Techniques; Enzyme Inhibitors; Fluorescent Dyes; Isoenzymes; Kinetics; Kupffer Cells; Liver; Liver Neoplasms, Experimental; Male; Mitochondria; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Wistar; Rhodamine 123; Rhodamines; Tumor Cells, Cultured | 1996 |
Molecular mechanism of T-cell control of Chlamydia in mice: role of nitric oxide in vivo.
Topics: Animals; Arginine; Chlamydia Infections; Chlamydia trachomatis; Clone Cells; Immunity, Cellular; Mice; Mice, Inbred BALB C; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; T-Lymphocytes, Helper-Inducer | 1996 |
Flow-induced modulation of the permeability of endothelial cells cultured on microcarrier beads.
Topics: Animals; Arginine; Capillary Permeability; Cattle; Cells, Cultured; Coloring Agents; Cyclooxygenase Inhibitors; Cytochalasin D; Dextrans; Endothelium, Vascular; Epoprostenol; Fluorescein; Fluoresceins; Hemorheology; Indicator Dilution Techniques; Indomethacin; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Stress, Mechanical; Vitamin B 12 | 1996 |
Effect of multiple cytokines plus bacterial endotoxin on glucose and nitric oxide production by cultured hepatocytes.
Topics: Animals; Arginine; Cells, Cultured; Cytokines; Drug Interactions; Enzyme Inhibitors; Glucose; Lipopolysaccharides; Liver; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Shock, Septic; Time Factors | 1996 |
Further observations on the role of nitric oxide in the feline lateral geniculate nucleus.
Topics: Afferent Pathways; Animals; Arginine; Cats; Electric Stimulation; Electroencephalography; Enzyme Inhibitors; gamma-Aminobutyric Acid; Geniculate Bodies; Iontophoresis; Models, Neurological; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Paralysis; Penicillamine; Photic Stimulation; S-Nitroso-N-Acetylpenicillamine; Synapses; Time Factors; Visual Fields; Visual Perception | 1996 |
Oxytocin-induced penile erection. Role of nitric oxide.
Topics: Animals; Arginine; Cyclic GMP; Enzyme Inhibitors; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Oxytocin; Paraventricular Hypothalamic Nucleus; Penile Erection; Rats; Rats, Sprague-Dawley | 1995 |
Amidines are potent inhibitors of nitric oxide synthases: preferential inhibition of the inducible isoform.
Topics: Amidines; Animals; Aorta; Arginine; Blood Pressure; Cattle; Cells, Cultured; Isoenzymes; Male; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Wistar | 1995 |
Nitric oxide modulation of Ca2+ responses in cow tracheal epithelium.
Topics: Adenosine Triphosphate; Animals; Arginine; Bradykinin; Calcium; Cattle; Epithelium; In Vitro Techniques; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Trachea | 1995 |
Activation of nitric oxide synthesis in vascular smooth muscle cells and macrophages during development in spontaneously hypertensive rats.
Topics: Aging; Animals; Arginine; Blood Pressure; Cell Division; Cells, Cultured; Concanavalin A; Enzyme Inhibitors; Hypertension; Lymphocytes; Macrophages; Male; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Species Specificity; Spleen | 1996 |
Vasodilator responses of rat isolated tail artery enhanced by oxygen- dependent, photochemical release of nitric oxide from iron-sulphur-nitrosyls.
Topics: Animals; Arginine; Arteries; Enzyme Inhibitors; In Vitro Techniques; Iron Chelating Agents; Lasers; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitroso Compounds; omega-N-Methylarginine; Oxygen; Oxyhemoglobins; Photolysis; Rats; Rats, Wistar; Superoxide Dismutase; Vasodilation; Vasodilator Agents | 1996 |
Increasing nitric oxide production improves survival in experimental hemorrhagic shock.
Topics: Analysis of Variance; Animals; Arginine; Blood Pressure; Disease Models, Animal; Enzyme Inhibitors; Male; Nitric Oxide; omega-N-Methylarginine; Prospective Studies; Random Allocation; Rats; Rats, Sprague-Dawley; Resuscitation; Shock, Hemorrhagic | 1996 |
Nitric oxide as a mediator of cocaine-induced penile erection in the rat.
Topics: Anesthetics, Local; Animals; Arginine; Cocaine; Dopamine; Enzyme Inhibitors; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; omega-N-Methylarginine; Penile Erection; Penis; Rats; Rats, Sprague-Dawley; Synaptic Transmission | 1996 |
Pharmacological characterization of nitric oxide production in a rat model of meningitis.
Topics: Animals; Arginine; Cells, Cultured; Cerebellum; Choroid Plexus; Escherichia coli; Leukocytes; Lipopolysaccharides; Male; Meninges; Meningitis; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley | 1996 |
Effects of the non-peptide, non-selective endothelin antagonist, bosentan, on regional haemodynamic responses to NG-monomethyl-L-arginine in conscious rats.
Topics: Animals; Arginine; Bosentan; Endothelin Receptor Antagonists; Enzyme Inhibitors; Hemodynamics; Male; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Sulfonamides | 1996 |
Ageing is associated with reduced basal and stimulated release of nitric oxide by the coronary endothelium.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aging; Animals; Arginine; Coronary Circulation; Coronary Vessels; Endothelium, Vascular; Enzyme Inhibitors; Male; Nitric Oxide; omega-N-Methylarginine; Perfusion; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Sprague-Dawley; Thromboxane A2; Vasoconstrictor Agents | 1996 |
The influence of ammonium persulfate on guinea pig tracheal muscle tone: release of nitric oxide.
Topics: Acetylcholine; Ammonium Sulfate; Animals; Arginine; Enzyme Inhibitors; Female; Guinea Pigs; In Vitro Techniques; Muscle, Smooth; Nitric Oxide; omega-N-Methylarginine; Trachea | 1996 |
Exogenous nitric oxide stimulates mucin secretion from LS174T colonic adenocarcinoma cells.
Topics: Adenocarcinoma; Animals; Arginine; Carcinoid Tumor; Cell Survival; Colonic Neoplasms; Epithelial Cells; Epithelium; Humans; Isotope Labeling; Mice; Mice, Inbred BALB C; Mice, Nude; Mucins; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Tumor Cells, Cultured; Vasodilator Agents | 1996 |
Effects of the naturally occurring arginine analogues indospicine and canavanine on nitric oxide mediated functions in aortic endothelium and peritoneal macrophages.
Topics: Animals; Aorta; Arginine; BCG Vaccine; Canavanine; Cells, Cultured; Cytochrome c Group; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Induction; Enzyme Inhibitors; Macrophages, Peritoneal; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Norleucine; omega-N-Methylarginine; Oxidation-Reduction; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate | 1996 |
Indirect evidence for stimulation of nitric oxide release by tumour necrosis factor-alpha in human veins in vivo.
Topics: Adult; Arginine; Dose-Response Relationship, Drug; Humans; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phenylephrine; Shock, Septic; Tumor Necrosis Factor-alpha; Vasodilation; Veins | 1995 |
Mechanism of hypertension induced by chronic inhibition of nitric oxide in rats.
Topics: Animals; Arginine; Blood Pressure; Catecholamines; Enzyme Inhibitors; Heart Rate; Hemodynamics; Hypertension; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Rats; Rats, Wistar; Time Factors | 1995 |
Cyclic GMP generation mediated by 5-HT-2 receptors via nitric oxide-dependent pathway and its effect on the desensitization of 5-HT-2 receptors in C6 glioma cells.
Topics: Animals; Arginine; Calcium; Chelating Agents; Cyclic GMP; Dopamine Antagonists; Edetic Acid; Egtazic Acid; Glioma; Haloperidol; Ketanserin; Nitric Oxide; omega-N-Methylarginine; Rats; Receptors, Serotonin; Risperidone; Serotonin Antagonists; Tropanes; Tumor Cells, Cultured | 1995 |
L-N6-(1-iminoethyl)-lysine potently inhibits inducible nitric oxide synthase and is superior to NG-monomethyl-arginine in vitro and in vivo.
Topics: Animals; Arginine; Cells, Cultured; Enzyme Inhibitors; Female; Leishmaniasis; Lysine; Macrophages; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase; omega-N-Methylarginine | 1995 |
Nitric oxide regulates insulin secretion in the isolated perfused human pancreas via a cholinergic mechanism.
Topics: Acetylcholine; Adolescent; Adult; Arginine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Glucose; Humans; In Vitro Techniques; Infusion Pumps; Insulin; Insulin Secretion; Islets of Langerhans; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Pancreas | 1996 |
Attenuated Salmonella vaccine-induced suppression of murine spleen cell responses to mitogen is mediated by macrophage nitric oxide: quantitative aspects.
Topics: Animals; Arginine; Bacterial Vaccines; Concanavalin A; Enzyme Inhibitors; Female; Immunosuppression Therapy; Interferon-gamma; Lymphocyte Activation; Mice; Mice, Inbred C3H; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Salmonella typhimurium; Spleen; Vaccines, Attenuated | 1996 |
Development of NADPH-diaphorase in the avian retina: regulation by calcium ions and relation to nitric oxide synthase.
Topics: Animals; Arginine; Calcium; Chick Embryo; Enzyme Activation; Enzyme Inhibitors; Histocytochemistry; Ions; NADPH Dehydrogenase; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Retina | 1996 |
L-[3H]nitroarginine and L-[3H]arginine uptake into rat cerebellar synaptosomes: kinetics and pharmacology.
Topics: Amino Acids; Animals; Arginine; Biological Transport; Cerebellum; Enzyme Inhibitors; Kinetics; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Synaptosomes; Tritium | 1996 |
[The mechanism of the action of low doses of thyroid hormones on the stressor-induced changes in rat vascular tonus].
Topics: Animals; Antithyroid Agents; Arginine; Blood Pressure; Coronary Vessels; Dose-Response Relationship, Drug; Drug Interactions; Female; In Vitro Techniques; Muscle Tonus; Muscle, Smooth, Vascular; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Restraint, Physical; Stress, Physiological; Thyroid Hormones; Time Factors | 1995 |
Human monocytes induce a carcinoma cell line to secrete high amounts of nitric oxide.
Topics: Arginine; Carcinoma, Transitional Cell; Coculture Techniques; Drug Combinations; Humans; Interleukin-1; Kidney Medulla; Leucine; Macrophage Activation; Monocytes; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Solubility; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Urinary Bladder Neoplasms | 1996 |
Counterprotective effect of erythrocytes in experimental bacterial peritonitis is due to scavenging of nitric oxide and reactive oxygen intermediates.
Topics: Animals; Antioxidants; Arginine; Enzyme Inhibitors; Enzymes; Erythrocytes; Escherichia coli Infections; Free Radical Scavengers; Macrophages, Peritoneal; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Oxidation-Reduction; Peritoneal Cavity; Peritonitis; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Rhodamines; RNA, Messenger | 1996 |
Roles for tumor necrosis factor alpha and nitric oxide in resistance of rat alveolar macrophages to Legionella pneumophila.
Topics: Animals; Arginine; Colony Count, Microbial; Endotoxins; Immunity, Innate; Interferon-gamma; Legionella pneumophila; Legionnaires' Disease; Lipopolysaccharides; Macrophage Activation; Macrophages, Alveolar; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Stereoisomerism; Tumor Necrosis Factor-alpha | 1996 |
Nitric oxide activity is deficient in spasm arteries of patients with coronary spastic angina.
Topics: Acetylcholine; Adult; Aged; Angina Pectoris; Arginine; Coronary Vasospasm; Diltiazem; Female; Humans; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Nitroglycerin; omega-N-Methylarginine; Sodium Chloride; Vasoconstrictor Agents; Vasodilator Agents | 1996 |
Ca(2+)-dependent nitric oxide release in endothelial but not R3230Ac rat mammary adenocarcinoma cells.
Topics: Adenocarcinoma; Animals; Arginine; Calcium; Calcium-Transporting ATPases; Cell Line; Endothelium, Vascular; Female; Fibroblasts; Humans; Immunoblotting; Isoenzymes; Mammary Neoplasms, Experimental; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Thapsigargin | 1996 |
Dengue virus-induced cytotoxin releases nitrite by spleen cells.
Topics: Animals; Arginase; Arginine; Calcium; Cell Culture Techniques; Cytokines; Cytotoxicity, Immunologic; Cytotoxins; Dengue Virus; Dose-Response Relationship, Immunologic; Immune Sera; Mice; Mice, Inbred Strains; Nitric Oxide; Nitrites; omega-N-Methylarginine; Proteins; Spleen; Sulfates; Zinc Compounds; Zinc Sulfate | 1996 |
Tyrosine kinase inhibitors prevent cytokine-induced expression of iNOS and COX-2 by human islets.
Topics: Arginine; Base Sequence; Benzoquinones; Cyclooxygenase Inhibitors; Cytokines; Enzyme Induction; Enzyme Inhibitors; Genistein; Humans; Interferon-gamma; Interleukin-1; Islets of Langerhans; Isoenzymes; Isoflavones; Lactams, Macrocyclic; Molecular Probes; Molecular Sequence Data; Nitric Oxide Synthase; omega-N-Methylarginine; Protein-Tyrosine Kinases; Quinones; Recombinant Proteins; Rifabutin; Tumor Necrosis Factor-alpha | 1996 |
Enhanced vasodilation to acetylcholine in athletes is associated with lower plasma cholesterol.
Topics: Acetylcholine; Adult; Angiotensin II; Arginine; Cholesterol; Endothelium, Vascular; Enzyme Inhibitors; Exercise; Forearm; Humans; Male; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; omega-N-Methylarginine; Regional Blood Flow; Vasoconstrictor Agents; Vasodilation | 1996 |
Local 24-h hyperglycemia does not affect endothelium-dependent or -independent vasoreactivity in humans.
Topics: Acetylcholine; Adult; Arginine; Endothelium, Vascular; Enzyme Inhibitors; Hemodynamics; Hormones; Humans; Hyperglycemia; Male; Nitric Oxide Synthase; Nitroprusside; Norepinephrine; omega-N-Methylarginine; Time Factors; Vasoconstrictor Agents; Vasodilator Agents; Vasomotor System | 1996 |
Endothelin induces vasoconstriction in the bone vasculature in vitro: an effect mediated by a single receptor population.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Arteries; Bone and Bones; Dogs; Dose-Response Relationship, Drug; Endothelins; Enzyme Inhibitors; Female; Indomethacin; Male; omega-N-Methylarginine; Organ Culture Techniques; Receptors, Endothelin; Regional Blood Flow; Vasoconstriction | 1996 |
Cerebral blood flow decreases following microinjection of sodium nitroprusside into the nucleus tractus solitarii of anesthetized rats.
Topics: Animals; Arginine; Cerebrovascular Circulation; Enzyme Inhibitors; Laser-Doppler Flowmetry; Male; Microinjections; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Rats; Rats, Wistar; Solitary Nucleus | 1996 |
Exercise-induced vasodilation in forearm circulation of normal subjects and patients with congestive heart failure: role of endothelium-derived nitric oxide.
Topics: Adult; Aged; Arginine; Blood Flow Velocity; Blood Pressure; Exercise Test; Female; Forearm; Hand Strength; Heart Failure; Humans; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Plethysmography; Regional Blood Flow; Vasodilation | 1996 |
Endothelium-derived nitric oxide regulates systemic and pulmonary vascular resistance during acute hypoxia in humans.
Topics: Acute Disease; Adult; Arginine; Blood Pressure; Female; Hemodynamics; Humans; Hypoxia; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Pulmonary Circulation; Vascular Resistance; Vasoconstriction; Vasodilation | 1996 |
Smooth muscle-derived nitric oxide is elevated in isolated forearm veins in human alcoholic cirrhosis.
Topics: Acetylcholine; Animals; Arginine; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Forearm; Humans; Liver Cirrhosis, Alcoholic; Male; Middle Aged; Muscle, Smooth, Vascular; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Plethysmography; Rats; Regional Blood Flow; Vascular Resistance; Veins | 1996 |
Quantitation of nitric oxide using 2-phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl 3-oxide (PTIO).
Topics: Animals; Arginine; Cell Line; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Imidazoles; Indicators and Reagents; Interferon-gamma; Kinetics; Lipopolysaccharides; Liposomes; Macrophages; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Spin Labels | 1996 |
Nitric oxide synthase inhibitors: amino acids.
Topics: Amino Acids; Animals; Arginine; Citrulline; Enzyme Inhibitors; Isoenzymes; Kinetics; Macrophages; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rodentia; Structure-Activity Relationship; Thiourea | 1996 |
Selective inhibition of inducible nitric oxide synthase by aminoguanidine.
Topics: Animals; Arginine; Brain; Cell Line; Endothelium, Vascular; Enzyme Induction; Enzyme Inhibitors; Guanidines; Iliac Artery; Insulinoma; Interleukin-1; Isoenzymes; Kinetics; Male; Molecular Structure; Nitric Oxide Synthase; omega-N-Methylarginine; Pancreatic Neoplasms; Rats; Rats, Sprague-Dawley; Recombinant Proteins | 1996 |
Human pancreatic islet beta-cell destruction by cytokines involves oxygen free radicals and aldehyde production.
Topics: Aldehydes; Antioxidants; Arginine; Autoimmune Diseases; Cytokines; Diabetes Mellitus, Type 1; DNA; Enzyme Inhibitors; Ethylamines; Free Radicals; Humans; Insulin; Interferon-gamma; Interleukin-1; Islets of Langerhans; Malondialdehyde; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Piperazines; Pyridines; Reactive Oxygen Species; Tumor Necrosis Factor-alpha | 1996 |
Bacterial superantigen-induced human lymphocyte responses are nitric oxide dependent and mediated by IL-12 and IFN-gamma.
Topics: Animals; Antibodies, Monoclonal; Arginine; Bacterial Proteins; Base Sequence; DNA Primers; Enzyme Inhibitors; Exotoxins; Humans; In Vitro Techniques; Interferon-gamma; Interleukin-12; Kinetics; Lymphocyte Activation; Lymphocytes; Lymphotoxin-alpha; Membrane Proteins; Mice; Molecular Sequence Data; Neutralization Tests; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Superantigens | 1996 |
Effects L-NG-nitro arginine methyl ester (L-NAME), L-NG-monomethyl arginine (L-NMMA) and L-arginine on the antinociceptive effects of morphine in mice.
Topics: Animals; Arginine; Enzyme Inhibitors; Male; Mice; Mice, Inbred Strains; Morphine; NG-Nitroarginine Methyl Ester; omega-N-Methylarginine; Pain Measurement | 1995 |
NG-methyl-L-arginine and somatostatin decrease glucose and insulin and block endothelin-1 (ET-1)-induced insulin release but not ET-1-induced hypoglycemia.
Topics: Animals; Arginine; Blood Glucose; Endothelins; Hypoglycemia; Insulin; Insulin Antagonists; Male; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Somatostatin | 1995 |
The effect of methylmercury (CH3HgCl) on the production of endothelium-derived relaxing factor (EDRF) by cultured human umbilical vascular endothelial cells based on its anti-aggregatory effect on human platelets.
Topics: Arginine; Bradykinin; Cells, Cultured; Endothelium, Vascular; Humans; Indomethacin; Methylmercury Compounds; Nitric Oxide; omega-N-Methylarginine; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombin; Umbilical Arteries | 1995 |
Cytokine-treated human neutrophils contain inducible nitric oxide synthase that produces nitration of ingested bacteria.
Topics: Arginine; Bacteria; Blood Bactericidal Activity; Blotting, Western; Enzyme Induction; Enzyme Inhibitors; Humans; In Situ Hybridization; Interferon-gamma; Interleukin-1; Monokines; Neutrophils; Nitric Oxide Synthase; omega-N-Methylarginine; Peroxidase; Phagocytosis; RNA, Messenger; Superoxides; Tumor Necrosis Factor-alpha; Tyrosine | 1996 |
Nitric oxide synthase in cat brain: cofactors--enzyme-substrate interaction.
Topics: Animals; Arginine; Brain; Calcium; Cats; Edetic Acid; Egtazic Acid; Female; Kinetics; Male; NADP; Nitric Oxide Synthase; omega-N-Methylarginine; Organ Specificity; Sulfonamides; Vasodilator Agents | 1996 |
A nitric oxide synthesis inhibitor prevents the ACTH-stimulated production of aldosterone in rat adrenal gland.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Arginine; Male; Nitric Oxide Synthase; omega-N-Methylarginine; Perfusion; Rats; Rats, Wistar | 1996 |
Binding of intermediate, product, and substrate analogs to neuronal nitric oxide synthase: ferriheme is sensitive to ligand-specific effects in the L-arginine binding site.
Topics: Animals; Arginine; Binding Sites; Cell Line; Citrulline; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Heme; Kidney; Neurons; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Ornithine; Rats | 1996 |
Role of basal release of nitric oxide in the presence of acute left ventricular dysfunction: comparative study with normal condition.
Topics: Acetylcholine; Acute Disease; Animals; Arginine; Blood Flow Velocity; Dogs; Enzyme Inhibitors; Femoral Artery; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Random Allocation; Ventricular Dysfunction, Left; Ventricular Function, Left | 1996 |
Nitric oxide inhibition of basal and neurogenic mucus secretion in ferret trachea in vitro.
Topics: Animals; Arginine; Ferrets; In Vitro Techniques; Male; Mucus; Nitric Oxide; Nitric Oxide Synthase; Nitro Compounds; omega-N-Methylarginine; Trachea | 1996 |
Activation of the arginine-nitric oxide pathway in primary sensory neurons contributes to dipyrone-induced spinal and peripheral analgesia.
Topics: Analysis of Variance; Anesthesia, Spinal; Animals; Anti-Infective Agents, Urinary; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Dinoprostone; Dipyrone; Enzyme Inhibitors; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Spinal; Male; Methylene Blue; Neurons, Afferent; Nitric Oxide; omega-N-Methylarginine; Pain; Rats; Rats, Wistar | 1996 |
Attenuation of human nasal airway responses to bradykinin and histamine by inhibitors of nitric oxide synthase.
Topics: Adult; Albumins; Arginine; Bradykinin; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Enzyme Inhibitors; Female; Histamine; Histamine Antagonists; Humans; Male; Middle Aged; Nasal Cavity; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Vasoconstriction | 1996 |
Inhibitory effect of interferon-gamma activated ovine umbilical vein endothelial cells on the intracellular replication of Toxoplasma gondii.
Topics: Amino Acids; Animals; Arginine; Cattle; Cells, Cultured; Endothelium, Vascular; Fibroblasts; Humans; Immunity, Innate; Interferon-gamma; Macrophages; Mice; omega-N-Methylarginine; Recombinant Proteins; RNA, Protozoan; Sheep; Sheep Diseases; Toxoplasma; Toxoplasmosis, Animal; Tryptophan; Umbilical Veins; Uracil | 1996 |
[Effect of nitric oxide and cyclic guanosine monophosphate on desensitization of cholinergic neurons in Helix lucorum].
Topics: Aminoquinolines; Animals; Arginine; Cholinergic Antagonists; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Helix, Snails; In Vitro Techniques; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Second Messenger Systems | 1996 |
Neural barriers affect the action of nitric oxide synthase inhibitors in the intact chicken retina.
Topics: Animals; Arginine; Blood-Retinal Barrier; Chickens; Citrulline; Enzyme Inhibitors; In Vitro Techniques; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Ornithine; Pigment Epithelium of Eye; Retina | 1995 |
Attenuation of intrinsic active tone by endothelium-derived nitric oxide in aortae of spontaneously hypertensive rats with different levels of blood pressure.
Topics: Animals; Aorta, Thoracic; Arginine; Blood Pressure; Calcium; Endothelium, Vascular; Enzyme Inhibitors; Hypertension; In Vitro Techniques; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Potassium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasoconstriction | 1996 |
Alveolar macrophages autoregulate IL-1 and IL-6 production by endogenous nitric oxide.
Topics: Animals; Arginine; Cells, Cultured; Enzyme Inhibitors; Homeostasis; Interleukin-1; Interleukin-6; Lipopolysaccharides; Macrophages, Alveolar; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Penicillamine; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Sodium Nitrite; Tumor Necrosis Factor-alpha | 1996 |
Cyanide toxicity in mice pretreated with diethylamine nitric oxide complex.
Topics: Animals; Antidotes; Arginine; Cyanides; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydrazines; Lethal Dose 50; Male; Methemoglobin; Mice; Mice, Inbred ICR; Nitric Oxide Synthase; Nitrogen Oxides; omega-N-Methylarginine; Oxyhemoglobins; Rats | 1996 |
Endogenous endothelium-derived relaxing factor inhibits platelet adhesion under whole blood flow conditions ex vivo.
Topics: Animals; Arginine; Blood Circulation; Blood Platelets; Blood Pressure; Carbachol; Cyclic AMP; Cyclic GMP; Enzyme Inhibitors; Fibrinogen; Hemoglobins; In Vitro Techniques; Indicators and Reagents; Injections, Intravenous; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Parasympathomimetics; Platelet Adhesiveness; Rats; Rats, Sprague-Dawley | 1995 |
Is nitric oxide involved in 5-HT2B receptor-mediated contraction in the rat stomach fundus?
Topics: Animals; Arginine; Cyclic GMP; Gastric Fundus; In Vitro Techniques; Male; Muscle Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Wistar; Receptors, Serotonin | 1995 |
5,6-Dihydroxyindole-2-carboxylic acid, a diffusible melanin precursor, is a potent stimulator of lipopolysaccharide-induced production of nitric oxide by J774 macrophages.
Topics: Animals; Arginine; Cell Line; Cells, Cultured; Diffusion; Enzyme Inhibitors; Indoles; Lipopolysaccharides; Macrophage Activation; Macrophages; Melanins; Melanocytes; Mice; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Protein Precursors; Salmonella typhi | 1995 |
The role of nitric oxide in the metabolism of labeled glucose in isolated rat uterus. Influence of 17 beta-estradiol.
Topics: Animals; Arginine; Carbon Dioxide; Carbon Radioisotopes; Enzyme Inhibitors; Estradiol; Female; Glucose; Hemoglobins; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Ovariectomy; Rats; Rats, Wistar; Uterus | 1995 |
A nitric oxide synthesis inhibitor decreased prostaglandin production in rat mesenteric vasculature.
Topics: Animals; Arginine; Blood Pressure; Eicosanoids; Enzyme Inhibitors; In Vitro Techniques; Male; Mesenteric Arteries; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; Nucleotides, Cyclic; omega-N-Methylarginine; Perfusion; Prostaglandins; Rats; Rats, Wistar | 1996 |
Transport of nitric oxide synthase inhibitors through cationic amino acid carriers in human erythrocytes.
Topics: Arginine; Biological Transport; Cations; Erythrocytes; Ethylmaleimide; Humans; Kinetics; Lysine; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine | 1995 |
Role of nitric oxide in the induction and expression of morphine tolerance and dependence in mice.
Topics: Animals; Arginine; Drug Interactions; Male; Mice; Morphine Dependence; Naloxone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Pain Measurement; Substance Withdrawal Syndrome | 1996 |
Vasodilation by intrathecal lipopolysaccharide of the cerebral arteries after subarachnoid haemorrhage in dogs.
Topics: Analysis of Variance; Angiography; Animals; Arginine; Basilar Artery; Bradykinin; Citrulline; Cytokines; Dogs; Enzyme Inhibitors; Female; Injections, Spinal; Lipopolysaccharides; Male; Microscopy, Electron; Nitric Oxide Synthase; omega-N-Methylarginine; Subarachnoid Hemorrhage; Vasoconstrictor Agents; Vasodilation; Vasopressins | 1996 |
Attenuation of human chorionic gonadotropin release by nitric oxide in choriocarcinoma cell lines.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Arginine; Blotting, Western; Choriocarcinoma; Chorionic Gonadotropin; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Female; Hemoglobin A; Humans; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Tumor Cells, Cultured; Uterine Neoplasms | 1996 |
The effect of NG-monomethyl-L-arginine on bladder function.
Topics: Animals; Arginine; Cats; Enzyme Inhibitors; Female; Hypogastric Plexus; Male; Muscle Contraction; Muscle, Smooth; Nitric Oxide Synthase; omega-N-Methylarginine; Purinergic Antagonists; Sympathetic Nervous System; Urinary Bladder; Urination; Urodynamics | 1996 |
Arginine analogues inhibit responses mediated by ATP-sensitive K+ channels.
Topics: Adenosine Triphosphate; Animals; Arginine; Arterioles; Cats; Guanylate Cyclase; Hypercapnia; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Pia Mater; Potassium Channel Blockers; Potassium Channels; Rats; Vasodilation | 1996 |
Stimulation of nitric oxide-cyclic GMP pathway by L-arginine increases the release of hepatic lipase from cultured rat hepatocytes.
Topics: Alkaloids; Animals; Arginine; Carbazoles; Cyclic GMP; Enzyme Inhibitors; Indoles; Lipase; Liver; Methylene Blue; Nitric Oxide; omega-N-Methylarginine; Protein Kinase Inhibitors; Rats | 1996 |
Role of endothelium in control of forearm blood flow in patients with heart failure.
Topics: Acetylcholine; Adult; Aged; Arginine; Endothelium, Vascular; Forearm; Heart Failure; Humans; Male; Middle Aged; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Substance P; Vascular Resistance; Vasodilator Agents; Vasomotor System | 1996 |
Cytostasis is required for IL-1 induced nitric oxide production in transformed hamster fibroblasts.
Topics: Animals; Arginine; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Cytokines; Dose-Response Relationship, Drug; Growth Inhibitors; Indomethacin; Interleukin-1; Mesocricetus; Nitric Oxide; omega-N-Methylarginine | 1996 |
Nitric oxide synthase does not participate in negative inotropic effect of acetylcholine in frog heart.
Topics: Acetylcholine; Animals; Arginine; Calcium; Electric Conductivity; Isoproterenol; Kinetics; Muscarine; Myocardial Contraction; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Patch-Clamp Techniques; Rana catesbeiana; Rana esculenta | 1996 |
Microbial killing by human neutrophil cytokineplasts: similar suppressive effects of reversible and irreversible inhibitors of nitric oxide synthase.
Topics: Arginine; Blood Bactericidal Activity; Cytotoxicity, Immunologic; Enzyme Inhibitors; Humans; Neutrophils; Nitric Oxide Synthase; omega-N-Methylarginine; Onium Compounds; Ornithine; Serratia marcescens; Staphylococcus aureus | 1996 |
Presence of nitric oxide synthase activity in roots and nodules of Lupinus albus.
Topics: Arginine; Citrulline; Enzyme Inhibitors; NADPH Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Plant Roots; Plants; Rhizobiaceae | 1996 |
Long-term smoking impairs platelet-derived nitric oxide release.
Topics: Adult; Arginine; Blood Platelets; Collagen; Cyclic GMP; Electric Conductivity; Humans; In Vitro Techniques; Male; Membrane Potentials; Nitric Oxide; omega-N-Methylarginine; Penicillamine; Platelet Aggregation; Reference Values; Regression Analysis; S-Nitroso-N-Acetylpenicillamine; Smoking; Vasodilator Agents | 1996 |
Role of cyclic nucleotides in contraction induced by oxytocin in the testicular capsule of the rat in vitro.
Topics: Animals; Arginine; Caffeine; Cyclic AMP; Cyclic GMP; Guanylate Cyclase; Male; omega-N-Methylarginine; Oxytocin; Phosphodiesterase Inhibitors; Rats; Rats, Wistar; Testis; Theophylline | 1996 |
Zymosan-activated plasma induces paw oedema by nitric oxide and prostaglandin production.
Topics: Animals; Arginine; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Edema; Enzyme Inhibitors; Foot Diseases; Hemoglobins; Indomethacin; Inflammation; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Prostaglandins; Rats; Zymosan | 1997 |
Bacterial infection induces nitric oxide synthase in human neutrophils.
Topics: Adult; Aged; Anti-Bacterial Agents; Arginine; Bacterial Infections; Blotting, Western; Canavanine; Cell Membrane; Citrulline; Female; Guanidines; Humans; Immunohistochemistry; Isoenzymes; Leukocyte Common Antigens; Male; Middle Aged; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Ornithine; Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Thiourea; Trifluoperazine; Urinary Tract Infections | 1997 |
Insulin and the arginine paradox.
Topics: Animals; Arginine; Arteriosclerosis; Cell Adhesion; Cells, Cultured; Endothelium; Humans; Insulin; Macrophages; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rabbits; Vasodilation | 1997 |
L-arginine reduces human monocyte adhesion to vascular endothelium and endothelial expression of cell adhesion molecules.
Topics: Arginine; Blotting, Northern; Cell Adhesion; Cells, Cultured; Drug Combinations; Endothelium, Vascular; Humans; Intercellular Adhesion Molecule-1; Molsidomine; Monocytes; omega-N-Methylarginine; Vascular Cell Adhesion Molecule-1 | 1997 |
Role of endogenous nitric oxide in airway microvascular leakage induced by inflammatory mediators.
Topics: Aminoquinolines; Animals; Arginine; Asthma; Capillary Permeability; Coloring Agents; Dipeptides; Enzyme Inhibitors; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Guanylate Cyclase; Guinea Pigs; Histamine; Indoles; Inflammation Mediators; Injections, Intravenous; Leukotriene D4; Lung; Male; Microcirculation; Neurokinin-1 Receptor Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Organometallic Compounds; Substance P | 1997 |
Differential effects of nitric oxide synthase modulation on porcine systemic and pulmonary circulation in vivo.
Topics: Acetylcholine; Animals; Arginine; Blood Pressure; Cyclooxygenase Inhibitors; Drug Interactions; Enzyme Inhibitors; Indomethacin; Infusions, Intravenous; Nitric Oxide Synthase; omega-N-Methylarginine; Pulmonary Circulation; Swine | 1997 |
NO modulates autonomic effects on sinus discharge rate and AV nodal conduction in open-chest dogs.
Topics: Acetylcholine; Animals; Arginine; Atrioventricular Node; Autonomic Nervous System; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Male; Neural Conduction; Nitric Oxide; omega-N-Methylarginine; Osmolar Concentration; Sinoatrial Node; Sympathetic Nervous System; Time Factors; Vagus Nerve | 1997 |
Cyclooxygenase inhibition restores nitric oxide activity in essential hypertension.
Topics: Acetylcholine; Arginine; Cyclooxygenase Inhibitors; Female; Forearm; Humans; Hypertension; Indomethacin; Male; Middle Aged; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Regional Blood Flow; Vasodilation; Vasodilator Agents | 1997 |
Vascular endothelial growth factor/vascular permeability factor augments nitric oxide release from quiescent rabbit and human vascular endothelium.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Calcium Chloride; Cells, Cultured; Endothelial Growth Factors; Endothelium, Vascular; Humans; In Vitro Techniques; Kinetics; Lymphokines; Male; Neovascularization, Physiologic; Nitric Oxide; omega-N-Methylarginine; Polarography; Pulmonary Artery; Rabbits; Umbilical Veins; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Vena Cava, Inferior | 1997 |
Evidence that nitric oxide inhibits steroidogenesis in cultured rat granulosa cells.
Topics: Animals; Arginine; Cells, Cultured; Coculture Techniques; Dose-Response Relationship, Drug; Female; Granulosa Cells; Guanidines; Macrophages; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroprusside; omega-N-Methylarginine; Penicillamine; Progesterone; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents | 1997 |
Endogenous NO-synthase is effective as a modulator of spinal thermosensitive neurons.
Topics: Action Potentials; Animals; Arginine; Body Temperature Regulation; Hot Temperature; In Vitro Techniques; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Rats; Spinal Cord; Thermoreceptors | 1997 |
Influence of basal release of nitric oxide on systolic and diastolic function of both ventricles.
Topics: Animals; Arginine; Diastole; Enzyme Inhibitors; Female; In Vitro Techniques; Male; Nitric Oxide; omega-N-Methylarginine; Oxygen Consumption; Swine; Systole; Ventricular Function, Left; Ventricular Function, Right | 1997 |
Vascular effects of acute hyperglycemia in humans are reversed by L-arginine. Evidence for reduced availability of nitric oxide during hyperglycemia.
Topics: Acute Disease; Adult; Arginine; Blood Viscosity; Catecholamines; Female; Free Radicals; Glucose; Glutathione; Hemodynamics; Humans; Hyperglycemia; Insulin; Lysine; Male; Nitric Oxide; omega-N-Methylarginine; Platelet Aggregation; Vasoconstriction | 1997 |
Mechanisms of arginine-induced increase in cytosolic calcium concentration in the beta-cell line NIT-1.
Topics: Animals; Arginine; Calcium; Cell Line; Cytosol; Diazoxide; Homoarginine; Insulin; Insulin Secretion; Insulinoma; Kinetics; Mice; Mice, Transgenic; Molsidomine; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Pancreatic Neoplasms; Potassium Channels; Potassium Chloride; Tumor Cells, Cultured; Verapamil | 1997 |
Impairment of osteoblast growth by nitric oxide synthase inhibitors: an effect independent of nitric oxide and arginine transport inhibition.
Topics: Animals; Arginine; Cell Division; Cells, Cultured; Humans; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Ornithine; Osteoblasts; Rats | 1996 |
Effect of nitric oxide synthase inhibition on renal hemodynamics in humans: reversal by L-arginine.
Topics: Adult; Arginine; Enzyme Inhibitors; Hemodynamics; Humans; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Renal Circulation; Respiration | 1997 |
High-performance liquid chromatographic determination of nitric oxide synthase-related arginine derivatives in vitro and in vivo.
Topics: Animals; Arginine; Cells, Cultured; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Female; Humans; In Vitro Techniques; Macrophages, Alveolar; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Reference Values; Reproducibility of Results; Sensitivity and Specificity | 1997 |
Electrogenic arginine transport mediates stimulus-secretion coupling in mouse pancreatic beta-cells.
Topics: Alternative Splicing; Aniline Compounds; Animals; Arginine; Biological Transport; Calcium; Carrier Proteins; Electric Conductivity; Enzyme Inhibitors; Exocytosis; Fluorescent Dyes; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Membrane Glycoproteins; Membrane Potentials; Membrane Proteins; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Receptors, Virus; RNA, Messenger; Xanthenes | 1997 |
Cytotoxic action of alpha-linolenic and eicosapentaenoic acids on myeloma cells in vitro.
Topics: alpha-Linolenic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Arginine; Calmodulin; Cell Division; Cell Survival; Cyclooxygenase Inhibitors; Eicosapentaenoic Acid; Fatty Acids, Unsaturated; Glutathione; Indomethacin; Lipoxygenase Inhibitors; Mice; Multiple Myeloma; omega-N-Methylarginine; Prostaglandins; Tumor Cells, Cultured; Vitamin E | 1997 |
Role of endogenous nitric oxide in the control of exocrine and endocrine pancreatic secretion in humans.
Topics: Adult; Amylases; Arginine; Ceruletide; Chymotrypsin; Gastrointestinal Agents; Humans; Islets of Langerhans; Lipase; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Pancreatic Hormones; Pancreatic Juice; Secretin; Trypsin | 1997 |
Inhibition of NO synthesis minimally affects the dynamic baroreflex regulation of sympathetic nerve activity.
Topics: Animals; Arginine; Baroreflex; Carotid Sinus; Enzyme Inhibitors; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rabbits; Sympathetic Nervous System | 1997 |
Agmatine affects glomerular filtration via a nitric oxide synthase-dependent mechanism.
Topics: Agmatine; Animals; Arginine; Cyclic GMP; Enzyme Activation; Enzyme Inhibitors; Glomerular Filtration Rate; Nitric Oxide Synthase; omega-N-Methylarginine; Perfusion; Rats; Receptors, Adrenergic, alpha-2; Signal Transduction | 1997 |
Effect of nicotine on the intimal hyperplasia after endothelial removal of the rabbit carotid artery.
Topics: Animals; Arginine; Body Weight; Carotid Arteries; Endothelin-1; Endothelium, Vascular; Hyperplasia; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nicotine; Nitric Oxide Synthase; omega-N-Methylarginine; Rabbits; Tunica Intima | 1997 |
Nitric oxide regulatory role in sensitized guinea pig trachea.
Topics: Acetylcholine; Animals; Arginine; Enzyme Inhibitors; Guinea Pigs; In Vitro Techniques; Isomerism; Male; Muscle Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Ovalbumin; Serine Proteinase Inhibitors; Trachea | 1997 |
Citrulline-argininosuccinate-arginine cycle coupled to Ca2+-signaling in rat pancreatic beta-cells.
Topics: Animals; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Argininosuccinic Acid; Calcium; Cells, Cultured; Citrulline; Cytosol; Immunohistochemistry; Insulinoma; Islets of Langerhans; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Pancreatic Neoplasms; Polymerase Chain Reaction; Rats; Rats, Wistar; RNA, Messenger; Signal Transduction; Transcription, Genetic; Tumor Cells, Cultured | 1997 |
An arginine analog inhibits responses of both the endothelium and smooth muscle of canine in situ vein grafts.
Topics: Adrenergic alpha-Agonists; Animals; Arginine; Brimonidine Tartrate; Calcimycin; Dogs; Endothelium, Vascular; Enzyme Inhibitors; Femoral Artery; Femoral Vein; Graft Occlusion, Vascular; Ionophores; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Organ Culture Techniques; Quinoxalines; Vascular Resistance; Veins | 1997 |
Nitric oxide formation lowers norepinephrine-induced intrahepatic resistance without major effects on the metabolism in the perfused rat liver.
Topics: Animals; Arginine; Bile; Blotting, Western; Dose-Response Relationship, Drug; Glucose; In Vitro Techniques; Lactic Acid; Lipopolysaccharides; Liver; Male; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; omega-N-Methylarginine; Portal Pressure; Rats; Rats, Wistar; Time Factors | 1997 |
Nitric oxide inhibits IgE-mediated degranulation of mast cells and is the principal intermediate in IFN-gamma-induced suppression of exocytosis.
Topics: Animals; Arginine; Cell Degranulation; Cell Separation; Exocytosis; Female; Gene Deletion; Glutathione; Immunoglobulin E; Immunosuppressive Agents; Interferon gamma Receptor; Interferon-gamma; Mast Cells; Mice; Mice, Knockout; Nitric Oxide; Nitrites; Nitroprusside; Nitroso Compounds; omega-N-Methylarginine; Receptors, Interferon; S-Nitrosoglutathione | 1997 |
Endogenously produced nitric oxide increases tumor necrosis factor-alpha production in transfected human U937 cells.
Topics: Animals; Arginine; Cell Differentiation; Citrulline; Cyclic GMP; DNA, Complementary; Enzyme Induction; Gene Expression Regulation, Neoplastic; Genetic Vectors; Humans; Lymphoma, Large B-Cell, Diffuse; Mice; Neoplasm Proteins; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Recombinant Fusion Proteins; Second Messenger Systems; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1997 |
A possible role of endogenous inhibitor for nitric oxide synthesis in the bovine ciliary muscle.
Topics: Animals; Arginine; Calcimycin; Cattle; Ciliary Body; Ionophores; Muscle Relaxation; Nitric Oxide; Nitroprusside; omega-N-Methylarginine | 1997 |
Role of nitric oxide in skeletal muscle blood flow at rest and during dynamic exercise in humans.
Topics: Adult; Analysis of Variance; Arginine; Exercise; Humans; Male; Microdialysis; Muscle, Skeletal; Nitric Oxide; omega-N-Methylarginine; Regional Blood Flow; Rest | 1997 |
Persistence of effects of nitric oxide synthase inhibitors: comparisons on blood flow and plasma exudation in guinea pig skin.
Topics: Animals; Arginine; Enzyme Inhibitors; Exudates and Transudates; Guinea Pigs; Iodine Radioisotopes; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Phenylephrine; Regional Blood Flow; Serum Albumin; Skin; Stereoisomerism; Vasoconstrictor Agents | 1997 |
NG-methyl-L-arginine, an inhibitor of nitric oxide synthase, affects the central nervous system to produce peripheral hyperglycemia in conscious rats.
Topics: Adrenalectomy; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Arginine; Biogenic Monoamines; Blood Glucose; Central Nervous System; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hyperglycemia; Injections, Intraventricular; Male; Narcotic Antagonists; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Wistar | 1997 |
Transport of L-arginine and the nitric oxide inhibitor NG-monomethyl-L-arginine in human erythrocytes in chronic renal failure.
Topics: Adult; Arginine; Biological Transport; Chromatography, High Pressure Liquid; Erythrocyte Membrane; Erythrocytes; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Renal Dialysis; Uremia | 1997 |
Nitric oxide synthase inhibitors and hypertension in children and adolescents.
Topics: Adolescent; Animals; Arginine; Child; Endothelium, Vascular; Enzyme Inhibitors; Female; Glomerular Filtration Rate; Humans; Hypertension; Hypertension, Renal; Hypertension, Renovascular; In Vitro Techniques; Male; Mice; Muscle Contraction; Nitric Oxide Synthase; omega-N-Methylarginine; Phenylephrine; Renin; Vasoconstrictor Agents | 1997 |
Basal release of nitric oxide augments the Frank-Starling response in the isolated heart.
Topics: Animals; Arginine; Cardiac Output; Coronary Circulation; Diastole; Female; Guinea Pigs; Hemoglobins; Male; Myocardium; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Organ Culture Techniques; Ventricular Pressure | 1997 |
Serum levels of NG, NG-dimethyl-L-arginine, a potential endogenous nitric oxide inhibitor in dialysis patients.
Topics: Arginine; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Humans; Nitric Oxide; omega-N-Methylarginine; Peritoneal Dialysis, Continuous Ambulatory; Renal Dialysis | 1997 |
Arginine metabolism in keratinocytes and macrophages during nitric oxide biosynthesis: multiple modes of action of nitric oxide synthase inhibitors.
Topics: Animals; Arginine; Cell Line; Citrulline; Dose-Response Relationship, Drug; Guanidines; Interferon-gamma; Keratinocytes; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Tumor Cells, Cultured | 1997 |
Substrate and substrate analog binding to endothelial nitric oxide synthase: electron paramagnetic resonance as an isoform-specific probe of the binding mode of substrate analogs.
Topics: Animals; Arginine; Cattle; Electron Spin Resonance Spectroscopy; Endothelium, Vascular; Enzyme Inhibitors; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Protein Binding; Substrate Specificity | 1997 |
L-arginine for testing endothelium-dependent vascular functions in health and disease.
Topics: Adenosine Diphosphate; Adult; Age Factors; Arginine; Blood Glucose; Blood Pressure; Blood Viscosity; Cholesterol; Diabetes Mellitus, Type 2; Diastole; Female; Humans; Hypercholesterolemia; Hypertension; Infusions, Intravenous; Male; Middle Aged; omega-N-Methylarginine; Platelet Aggregation; Reference Values; Regression Analysis; Smoking; Stereoisomerism; Systole | 1997 |
Adenosine receptor-mediated relaxation of rabbit airway smooth muscle: a role for nitric oxide.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Arginine; Bronchi; Dose-Response Relationship, Drug; Epithelium; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Phenethylamines; Potassium Chloride; Purinergic P1 Receptor Agonists; Rabbits; Receptors, Purinergic P1 | 1997 |
The role of nitric oxide as an effector of macrophage-mediated cytotoxicity against Trichomonas vaginalis.
Topics: Animals; Arginase; Arginine; Cells, Cultured; Cytotoxicity, Immunologic; Ferric Compounds; Interferon-gamma; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Nitric Oxide; omega-N-Methylarginine; Trichomonas vaginalis | 1997 |
Macrophage inflammatory protein-1 alpha production in lipopolysaccharide-stimulated human adherent blood mononuclear cells is inhibited by the nitric oxide synthase inhibitor N(G)-monomethyl-L-arginine.
Topics: Animals; Arginine; Cell Adhesion; Cell Line; Chemokine CCL2; Chemokine CCL4; Chemokine CCL5; Gene Expression Regulation; Humans; Interleukin-1; Interleukin-10; Interleukin-8; Leukocytes, Mononuclear; Lipopolysaccharides; Macrophage Inflammatory Proteins; Mice; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Substrate Specificity; Tumor Necrosis Factor-alpha | 1997 |
Role of nitric oxide in gut ischemia-reperfusion-induced hepatic microvascular dysfunction.
Topics: Alanine Transaminase; Animals; Arginine; Biological Availability; Intestines; Ischemia; Leukocytes; Liver Circulation; Mesenteric Arteries; Mesenteric Vascular Occlusion; Mice; Mice, Inbred C57BL; Microcirculation; NAD; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Triazenes | 1997 |
Nitric oxide contributes to substance P-induced increases in lung rapidly adapting receptor activity in guinea-pigs.
Topics: Adaptation, Physiological; Animals; Arginine; Blood Pressure; Enzyme Inhibitors; Guinea Pigs; Lung; Male; Microcirculation; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Respiratory Function Tests; Sensory Receptor Cells; Substance P; Substrate Specificity; Vagus Nerve | 1997 |
Inhibition of virulent Mycobacterium tuberculosis by Bcg(r) and Bcg(s) macrophages correlates with nitric oxide production.
Topics: Animals; Arginine; Carrier Proteins; Cation Transport Proteins; Cell Line; Disease Susceptibility; Immunity, Innate; Interferon-gamma; Iron-Binding Proteins; Macrophage Activation; Macrophages; Membrane Proteins; Mice; Mycobacterium tuberculosis; Nitric Oxide; omega-N-Methylarginine; Tuberculosis; Virulence | 1997 |
Cardiovascular effects of nitric oxide and N-methyl-D-aspartate receptors in the nucleus tractus solitarii of rats.
Topics: Animals; Arginine; Blood Pressure; Brain Mapping; Brain Stem; Excitatory Amino Acid Antagonists; Glutamic Acid; Heart Rate; Male; Microinjections; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Solitary Nucleus | 1997 |
Intrapericardial delivery of L-arginine reduces the increased severity of ventricular arrhythmias during sympathetic stimulation in dogs with acute coronary occlusion: nitric oxide modulates sympathetic effects on ventricular electrophysiological properti
Topics: Animals; Arginine; Confounding Factors, Epidemiologic; Disease Models, Animal; Dogs; Electric Stimulation; Enzyme Inhibitors; Myocardial Contraction; Myocardial Infarction; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; omega-N-Methylarginine; Pericardium; Severity of Illness Index; Tachycardia, Ventricular | 1997 |
Colocalization of demethylating enzymes and NOS and functional effects of methylarginines in rat kidney.
Topics: Amidohydrolases; Animals; Arginine; Blotting, Western; Enzyme Inhibitors; Hydrolases; Kidney Glomerulus; Loop of Henle; Male; Methylation; Microscopy, Immunoelectron; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Tritium | 1997 |
L-arginine decreases alveolar macrophage proinflammatory monokine production during acute lung injury by a nitric oxide synthase-dependent mechanism.
Topics: Analysis of Variance; Animals; Arginine; Bronchoalveolar Lavage Fluid; Drug Evaluation, Preclinical; Endotoxins; Enzyme Inhibitors; Interleukin-1; Macrophages, Alveolar; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Premedication; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome; Time Factors; Tumor Necrosis Factor-alpha | 1997 |
Possible role of nitric oxide in IgE-mediated allergic cutaneous reaction in mice.
Topics: Animals; Arginine; Dinitrofluorobenzene; Dinitrophenols; Edema; Female; Immunization, Passive; Immunoglobulin E; Interleukin-1; Mice; Mice, Inbred BALB C; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Tumor Necrosis Factor-alpha; Vasculitis, Leukocytoclastic, Cutaneous | 1998 |
Superoxide generation by renal proximal tubule nitric oxide synthase.
Topics: Analysis of Variance; Animals; Arginine; In Vitro Techniques; Kidney Tubules, Proximal; L-Lactate Dehydrogenase; Lipid A; Lipid Peroxidation; Male; Malondialdehyde; Nitrates; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Stereoisomerism; Superoxides | 1997 |
Effect of the nitric oxide level in the medial preoptic area on male copulatory behavior in rats.
Topics: Animals; Arginine; Copulation; Ejaculation; Female; Infusions, Parenteral; Male; Microdialysis; Nitrates; Nitric Oxide; Nitrites; omega-N-Methylarginine; Posture; Preoptic Area; Rats; Rats, Wistar; Time Factors | 1998 |
Influence of hyperthyroidism on the activity of liver nitric oxide synthase in the rat.
Topics: Animals; Arginine; Body Temperature; Enzyme Inhibitors; Female; Gadolinium; Hyperthyroidism; Kupffer Cells; Liver; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Triiodothyronine | 1997 |
Arginine in burn injury improves cardiac performance and prevents bacterial translocation.
Topics: Animals; Arginine; Bacterial Translocation; Burns; Coronary Circulation; Cyclic GMP; Fluid Therapy; Hemodynamics; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Resuscitation; Stereoisomerism; Ventricular Function | 1998 |
Role of nitric oxide in acetaminophen-induced hepatotoxicity in the rat.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Arginine; Cytochrome P-450 CYP2E1; Guanidines; Liver; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Rats | 1998 |
Increased L-arginine transport in human erythrocytes in chronic heart failure.
Topics: Amino Acids; Arginine; Biological Transport; Chromatography, High Pressure Liquid; Erythrocytes; Ethylmaleimide; Heart Failure; Humans; Nitric Oxide Synthase; omega-N-Methylarginine | 1998 |
Direct evidence for the role of nitric oxide on the glutamate-induced neuronal death in cultured cortical neurons.
Topics: Animals; Arginine; Cell Death; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Ketamine; Neurons; Nitric Oxide; omega-N-Methylarginine; Penicillamine; Rats; Rats, Wistar | 1998 |
Pharmacological manipulation of hippocampal nitric oxide synthesis affects the power of theta recorded from the dorsal hippocampus of urethane-anesthetized rat.
Topics: Anesthetics, Intravenous; Animals; Arginine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hippocampus; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Wistar; Theta Rhythm; Urethane | 1998 |
L-arginine inhibits smooth muscle cell proliferation of vein graft intimal thickness in hypercholesterolemic rabbits.
Topics: Acetylcholine; Analysis of Variance; Animals; Arginine; Bromodeoxyuridine; Cell Division; Citrulline; Graft Rejection; Hypercholesterolemia; In Vitro Techniques; Jugular Veins; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; omega-N-Methylarginine; Rabbits; Tunica Intima | 1997 |
Killing of blood stage Plasmodium vinckei petteri by spleen macrophages through L-arginine dependent mechanism.
Topics: Animals; Arginine; BCG Vaccine; Cells, Cultured; Disease Models, Animal; Female; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Mice, Inbred BALB C; omega-N-Methylarginine; Plasmodium; Rodentia; Spleen; Time Factors | 1997 |
Generation of nitric oxide by lapine meniscal cells and its effect on matrix metabolism: stimulation of collagen production by arginine.
Topics: Animals; Arginine; Cells, Cultured; Collagen; Dinoprostone; Interleukin-1; Lactic Acid; Menisci, Tibial; Nitric Oxide; omega-N-Methylarginine; Proteoglycans; Rabbits | 1998 |
Inhibition of nitric oxide synthase slows heart rate recovery from cholinergic activation.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Animals; Arginine; Calcium Channel Blockers; Cardiovascular Agents; Cesium; Electric Stimulation; Enzyme Inhibitors; Guinea Pigs; Heart Atria; Heart Rate; Male; Nifedipine; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; omega-N-Methylarginine; Pyrimidines; Vagus Nerve | 1998 |
Downregulation of nitric oxide synthase in chronic renal insufficiency: role of excess PTH.
Topics: Animals; Antihypertensive Agents; Arginine; Blood Platelets; Blood Pressure; Calcium; Calcium Channel Blockers; Cytosol; Enzyme Inhibitors; Kidney Failure, Chronic; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroprusside; omega-N-Methylarginine; Osmolar Concentration; Parathyroid Hormone; Parathyroidectomy; Rats; Rats, Sprague-Dawley | 1998 |
The inhibition by dantrolene of L-arginine transport and nitric oxide synthase in rat alveolar macrophages.
Topics: Animals; Arginine; Biological Transport; Calcium; Dantrolene; Interferon-gamma; Lipopolysaccharides; Macrophages, Alveolar; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley | 1998 |
Acid-induced duodenal mucosal nitric oxide output parallels bicarbonate secretion in the anaesthetized pig.
Topics: Anesthetics, Combined; Animals; Arginine; Bicarbonates; Duodenum; Enzyme Inhibitors; Female; Guanethidine; Hydrochloric Acid; In Vitro Techniques; Intestinal Mucosa; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Perfusion; Swine; Sympatholytics | 1998 |
Nitric oxide synthase inhibitors alter ventilation in isoflurane anesthetized rats.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Arginine; Carbon Dioxide; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hemodynamics; Indazoles; Isoflurane; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Respiration | 1998 |
Interaction of L-arginine analogs with L-arginine uptake in rat renal brush border membrane vesicles.
Topics: Animals; Arginine; Binding, Competitive; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Kidney Tubules, Proximal; Male; Microvilli; NG-Nitroarginine Methyl Ester; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley | 1998 |
Direct and continuous electrochemical measurement of noradrenaline-induced nitric oxide production in C6 glioma cells.
Topics: Animals; Arginine; Biosensing Techniques; Brain; Electrochemistry; Glioma; Interferon-gamma; Lipopolysaccharides; Neurons; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Signal Transduction; Tumor Cells, Cultured | 1998 |
Induction of nitric oxide synthase and nitric oxide-mediated apoptosis in neuronal PC12 cells after stimulation with tumor necrosis factor-alpha/lipopolysaccharide.
Topics: Animals; Apoptosis; Arginine; Biotin; Cell Differentiation; Deoxyuracil Nucleotides; DNA Fragmentation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Guanidines; Lipopolysaccharides; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; PC12 Cells; Rats; RNA, Messenger; Staining and Labeling; Thiazines; Transcription, Genetic; Tumor Necrosis Factor-alpha | 1998 |
Effect of atherosclerosis on endothelium-dependent inhibition of platelet activation in humans.
Topics: Acetylcholine; Arginine; Arteriosclerosis; Endothelium, Vascular; Female; Humans; In Vitro Techniques; Male; Middle Aged; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Platelet Activation; Platelet Aggregation | 1998 |
Contribution of nitric oxide to reactive hyperemia: impact of endothelial dysfunction.
Topics: Acetylcholine; Adult; Aged; Analysis of Variance; Arginine; Arteriosclerosis; Endothelium, Vascular; Female; Humans; Hyperemia; Hypertension; Leg; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Regression Analysis; Reproducibility of Results; Risk Factors; Sensitivity and Specificity; Time Factors; Vascular Resistance; Vasodilation; Vasodilator Agents | 1998 |
Calcium-dependent nitric oxide synthase activity in rat thymocytes.
Topics: Animals; Arginine; Calcium; CD2 Antigens; Citrulline; Immunohistochemistry; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Wistar; T-Lymphocytes; Thymus Gland | 1998 |
Reduction by tetrahydrobiopterin of H2O2-induced endothelial cell injury.
Topics: Animals; Arginine; Biopterins; Cattle; Cells, Cultured; Endothelium, Vascular; Hydrogen Peroxide; Ionomycin; omega-N-Methylarginine; Pteridines; Pterins; Rats; Serotonin | 1998 |
Nitric oxide synthase activity in human renal cell carcinoma.
Topics: Analysis of Variance; Anticarcinogenic Agents; Arginine; Calcium; Carcinogens; Carcinoma, Renal Cell; Cell Division; Cells, Cultured; Citrulline; DNA; Enzyme Inhibitors; Humans; Interleukin-2; Kidney Neoplasms; Kidney Tubules, Proximal; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Penicillamine; Thymidine; Tumor Cells, Cultured | 1998 |
The activation of eNOS by copper ion (Cu2+) in human pulmonary arterial endothelial cells (HPAEC).
Topics: Arginine; Calcium; Cations, Divalent; Cells, Cultured; Citrulline; Copper; Edetic Acid; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Humans; Luminescent Measurements; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Pulmonary Artery | 1998 |
Nitric oxide modulates gut ischemia-reperfusion-induced P-selectin expression in murine liver.
Topics: Animals; Antibodies, Monoclonal; Arginine; Crosses, Genetic; DEET; Intestinal Mucosa; Intestines; Ischemia; Leukocytes; Liver; Lung; Mesenteric Artery, Superior; Mice; Mice, Inbred C57BL; Nitric Oxide; omega-N-Methylarginine; P-Selectin; Rats; Reperfusion; Splanchnic Circulation | 1998 |
L-Arginine inhibits vasopressin-stimulated mesangial cell Ca2+.
Topics: Animals; Arginine; Arginine Vasopressin; Calcium; Cell Line, Transformed; Cells, Cultured; Glomerular Mesangium; Guanidine; Mice; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Spermidine; Spermine | 1998 |
Nitric oxide modulates cardiac contractility and oxygen consumption without changing contractile efficiency.
Topics: Animals; Arginine; Blood Pressure; Coronary Circulation; Dogs; Electrocardiography; Fiber Optic Technology; Heart; Myocardial Contraction; Myocardium; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Optical Fibers; Oximetry; Oxygen Consumption; Reproducibility of Results; Systole; Ventricular Function, Left | 1998 |
Molecular cloning and expression of inducible nitric oxide synthase in chick embryonic ventricular myocytes.
Topics: Amino Acid Sequence; Animals; Arginine; Blotting, Northern; Calcium; Cell Size; Chick Embryo; Cloning, Molecular; Conserved Sequence; Cyclic GMP; Enzyme Inhibitors; Gene Expression; Humans; Lipopolysaccharides; Molecular Sequence Data; Myocardial Contraction; Myocardium; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; RNA, Messenger; Sequence Homology, Amino Acid | 1998 |
iNOS expression in human intestinal microvascular endothelial cells inhibits leukocyte adhesion.
Topics: Arginine; Cell Adhesion; Cells, Cultured; DNA Primers; Endothelium, Vascular; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Humans; Intestinal Mucosa; Leukocytes; Lipopolysaccharides; Lysine; Microcirculation; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Polymerase Chain Reaction; Tumor Necrosis Factor-alpha; Umbilical Veins | 1998 |
Arginine-induced insulin release is decreased and glucagon increased in parallel with islet NO production.
Topics: Animals; Arginine; Diazoxide; Dose-Response Relationship, Drug; Female; Glucagon; Homoarginine; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Mice; Mice, Inbred Strains; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; omega-N-Methylarginine | 1998 |
L-arginine uptake in rat cerebral mitochondria.
Topics: Animals; Arginine; Biological Transport; Brain; Carbon Radioisotopes; Enzyme Inhibitors; Female; Kinetics; Lysine; Mitochondria; Nitric Oxide Synthase; omega-N-Methylarginine; Ornithine; Rats; Rats, Wistar | 1998 |
The role of nitric oxide in striatal acetylcholine release induced by N-methyl-D-aspartate.
Topics: Acetylcholine; Animals; Arginine; Corpus Striatum; Dibutyryl Cyclic GMP; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Piperazines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1998 |
The negative inotropic effect of beta3-adrenoceptor stimulation is mediated by activation of a nitric oxide synthase pathway in human ventricle.
Topics: Adrenergic beta-Agonists; Arginine; Cyclic GMP; Ethanolamines; Female; Heart; Heart Ventricles; Humans; Isoproterenol; Kinetics; Male; Middle Aged; Myocardial Contraction; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroarginine; Norepinephrine; omega-N-Methylarginine; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3 | 1998 |
Relationship between constitutive nitric oxide synthase activity and mucus level in the gastric mucosa of rats with stress.
Topics: Animals; Arginine; Enzyme Inhibitors; Gastric Mucosa; Guanidines; Male; Mucus; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Rats; Rats, Wistar; Stress, Physiological | 1998 |
Effect of nitric oxide synthase inhibition on the sympatho-vagal contol of heart rate.
Topics: Adrenergic Fibers; Animals; Arginine; Enzyme Inhibitors; Guinea Pigs; Heart Atria; Heart Rate; Indazoles; Isoproterenol; Male; Neural Inhibition; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Polymethacrylic Acids; Propranolol; Rabbits; Sympatholytics; Sympathomimetics; Vagus Nerve | 1998 |
Effects of changing the availability of the substrate for nitric oxide synthase by L-arginine administration on coronary vasomotor tone in angina patients with angiographically narrowed and in patients with normal coronary arteries.
Topics: Aged; Angina Pectoris; Arginine; Coronary Angiography; Coronary Artery Disease; Coronary Vessels; Endothelium, Vascular; Enzyme Inhibitors; Female; Humans; Male; Middle Aged; Nitric Oxide Synthase; Nitroglycerin; omega-N-Methylarginine; Substance P; Vasoconstriction | 1998 |
Effect of L-arginine-nitric oxide system on chemical-induced diabetes mellitus.
Topics: Alloxan; Animals; Antioxidants; Arginine; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Insulin; Ketone Bodies; Lactic Acid; Lipid Peroxides; Male; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Rats; Rats, Wistar | 1998 |
Decreased nitric oxide-mediated natural killer cell activation in chronic fatigue syndrome.
Topics: Adjuvants, Immunologic; Adult; Arginine; Base Sequence; Case-Control Studies; DNA Primers; Enzyme Inhibitors; Fatigue Syndrome, Chronic; Female; Humans; In Vitro Techniques; Killer Cells, Natural; Lymphocyte Subsets; Male; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Penicillamine; S-Nitroso-N-Acetylpenicillamine | 1998 |
Effect of inhibition of nitric oxide synthase on Pseudomonas aeruginosa infection of respiratory mucosa in vitro.
Topics: Arginine; Bacterial Adhesion; Enzyme Inhibitors; Gene Expression; Humans; Microscopy, Electron, Scanning; Mucous Membrane; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; omega-N-Methylarginine; Organ Culture Techniques; Pseudomonas aeruginosa; Respiratory System; RNA, Messenger | 1998 |
Relationship between mouse uterine contractility, nitric oxide and prostaglandin production in early pregnancy.
Topics: Animals; Arginine; Citrulline; Dinoprost; Enzyme Inhibitors; Female; Mice; Mice, Inbred Strains; Muscle Contraction; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Pregnancy; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Prostaglandins E; Uterus | 1998 |
Cardiovascular effects of nitric oxide and adenosine in the nucleus tractus solitarii of rats.
Topics: Adenosine; Animals; Arginine; Blood Pressure; Cardiovascular Agents; Enzyme Inhibitors; Heart Rate; Male; Microinjections; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Sodium Chloride; Solitary Nucleus; Xanthines | 1998 |
Escherichia coli lipopolysaccharide downregulates soluble guanylate cyclase in pulmonary artery smooth muscle.
Topics: Animals; Arginine; Cells, Cultured; Cyclic GMP; Down-Regulation; Enzyme Inhibitors; Escherichia coli; Guanylate Cyclase; Lipopolysaccharides; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Pulmonary Artery; Rats; RNA, Messenger | 1998 |
Role of endogenous nitric oxide in the nucleus tratus solitarii on baroreflex control of heart rate in spontaneously hypertensive rats.
Topics: Animals; Arginine; Baroreflex; Blood Pressure; Brain Stem; Enzyme Inhibitors; Heart Rate; Hypertension; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Solitary Nucleus | 1998 |
Role of nitric oxide and cGMP in human septic serum-induced depression of cardiac myocyte contractility.
Topics: Animals; Arginine; Blood Physiological Phenomena; Cyclic GMP; Drug Combinations; Enzyme Inhibitors; Humans; Interleukin-1; Methylene Blue; Myocardial Contraction; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nucleotides, Cyclic; omega-N-Methylarginine; Rats; Shock, Septic; Tumor Necrosis Factor-alpha | 1999 |
Non-enzymatic production of nitric oxide (NO) from NO synthase inhibitors.
Topics: Animals; Arginine; Mollusca; Nerve Tissue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Ornithine | 1998 |
Autoxidation rates of neuronal nitric oxide synthase: effects of the substrates, inhibitors, and modulators.
Topics: Animals; Arginine; Biopterins; Flow Injection Analysis; Kinetics; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Onium Compounds; Oxidation-Reduction; Rats; Spectrophotometry | 1998 |
Gamma interferon stimulates rat alveolar macrophages to kill Pneumocystis carinii by L-arginine- and tumor necrosis factor-dependent mechanisms.
Topics: Animals; Arginine; Female; Interferon-gamma; Macrophages, Alveolar; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Pneumocystis; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 1999 |
Inhibition of transforming growth factor beta production by nitric oxide-treated chondrocytes: implications for matrix synthesis.
Topics: Animals; Arginine; Cartilage, Articular; Cells, Cultured; Chondrocytes; Enzyme Inhibitors; Extracellular Matrix; Interleukin-1; Nitric Oxide; omega-N-Methylarginine; Penicillamine; Proteoglycans; Rabbits; S-Nitroso-N-Acetylpenicillamine; Transforming Growth Factor beta | 1999 |
A study on the effects of endogenous nitric oxide on coronary blood flow, myocardial oxygen extraction and cardiac contractility.
Topics: Animals; Arginine; Coronary Circulation; Dogs; Enzyme Inhibitors; Hemodynamics; Myocardial Contraction; Myocardium; Nitric Oxide; omega-N-Methylarginine; Oxygen Consumption; Papaverine; Systole; Vasodilation; Vasodilator Agents | 1999 |
Nitric oxide-dependent and -independent mechanisms in the relaxation elicited by acetylcholine in fetal rat aorta.
Topics: Acetylcholine; Animals; Aorta; Apamin; Arginine; Biological Factors; Dinoprost; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Nitric Oxide; omega-N-Methylarginine; Ouabain; Potassium Channel Blockers; Potassium Channels; Potassium Chloride; Rats; Rats, Wistar; Tetraethylammonium; Thiopental; Vasodilation | 1999 |
The NO synthase inhibitors L-Name and L-NMMA, but not L-arginine, block the mammalian nicotinic acetylcholine receptor channel.
Topics: Animals; Arginine; Cells, Cultured; Electric Stimulation; Enzyme Inhibitors; Ion Channel Gating; Ligands; Mice; Microtubules; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nicotinic Antagonists; Nitric Oxide Synthase; omega-N-Methylarginine; Patch-Clamp Techniques; Receptors, Nicotinic; Synaptic Transmission | 1998 |
Accelerated intimal hyperplasia and increased endogenous inhibitors for NO synthesis in rabbits with alloxan-induced hyperglycaemia.
Topics: Alloxan; Animals; Arginine; Blood Glucose; Body Weight; Carotid Arteries; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Hyperglycemia; Hyperplasia; In Vitro Techniques; Male; Nitric Oxide; omega-N-Methylarginine; Rabbits; Tunica Intima; Tunica Media; Weight Gain | 1999 |
Renal vasoconstriction induced by oxidized LDL is inhibited by scavengers of reactive oxygen species and L-arginine.
Topics: Animals; Arginine; Catalase; Cyclic GMP; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Free Radical Scavengers; Glomerular Filtration Rate; Indomethacin; Lipoproteins, LDL; Male; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Renal Artery; Superoxide Dismutase; Vasoconstriction | 1999 |
Relative roles of cyclooxygenase and nitric oxide synthase pathways in ischemia-induced increased contraction of cavernosal smooth muscle.
Topics: Animals; Arginine; Arteriosclerosis; Electric Stimulation; Enzyme Inhibitors; Hypercholesterolemia; Indomethacin; Ischemia; Male; Muscle Contraction; Muscle, Smooth; Nitric Oxide Synthase; omega-N-Methylarginine; Penis; Prostaglandin-Endoperoxide Synthases; Rabbits; Regional Blood Flow | 1999 |
Mechanism of superoxide generation by neuronal nitric-oxide synthase.
Topics: Arginine; Cell Line; Enzyme Inhibitors; Humans; Kidney; Kinetics; Models, Chemical; Nerve Tissue Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; omega-N-Methylarginine; Superoxides; Transfection | 1999 |
The role of nitric oxide in aloe-induced diarrhoea in the rat.
Topics: Aloe; Animals; Arginine; Body Water; Chelating Agents; Defecation; Diarrhea; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Feces; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Plants, Medicinal; Rats; Rats, Wistar | 1999 |
Hypoxia inhibits increased ETB receptor-mediated NO synthesis in hypertensive rat lungs.
Topics: Animals; Arginine; Biopterins; Egtazic Acid; Enzyme Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; In Vitro Techniques; Luminescent Measurements; Lung; Lysine; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Receptor, Endothelin B; Receptors, Endothelin; Time Factors | 1999 |
[The modulating effect of endothelial relaxing factor on the reactivity of the myocardium and of arterial vascular strips].
Topics: Animals; Arginine; Atrial Function; Carotid Arteries; Enzyme Inhibitors; Guinea Pigs; Heart; Heart Atria; In Vitro Techniques; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Norepinephrine; omega-N-Methylarginine; Perfusion; Rabbits; Vasoconstrictor Agents; Vasodilator Agents | 1999 |
L-arginine-induced growth hormone secretion is not influenced by co-infusion of the nitric oxide synthase inhibitor N-monomethyl-L-arginine in healthy men.
Topics: Adult; Analysis of Variance; Arginine; Drug Interactions; Human Growth Hormone; Humans; Infusions, Intravenous; Male; Nitric Oxide Synthase; omega-N-Methylarginine; Reference Values; Time Factors | 1999 |
Cardiovascular responses to muscle contraction following microdialysis of nitric oxide precursor into ventrolateral medulla.
Topics: Animals; Arginine; Blood Pressure; Brain Chemistry; Cardiovascular Physiological Phenomena; Enzyme Inhibitors; Female; gamma-Aminobutyric Acid; Glutamic Acid; Heart Rate; Male; Medulla Oblongata; Microdialysis; Muscle Contraction; Muscle, Skeletal; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley | 1999 |
Nitric oxide in the regulation of vasomotor tone in human skeletal muscle.
Topics: Acetylcholine; Adult; Arginine; Blood Pressure; Drug Interactions; Enzyme Inhibitors; Exercise; Femoral Artery; Heart Rate; Humans; Leg; Male; Muscle, Skeletal; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Oxygen Consumption; Regional Blood Flow; Vasomotor System | 1999 |
An enhancement of nitric oxide production regulates energy metabolism in rat hepatocytes after a partial hepatectomy.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Arginine; Cells, Cultured; Energy Metabolism; Hepatectomy; Humans; Interferon-gamma; Interleukin-1; Ketone Bodies; Kinetics; Liver; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Wistar; Recombinant Proteins | 1999 |
Stimulation of NO synthase activity in the immune-competent lepidopteran Estigmene acraea hemocyte line.
Topics: Animals; Arginine; Cell Line; Citrulline; Enzyme Activation; Enzyme Inhibitors; Hemocytes; Immunocompetence; Kinetics; Lepidoptera; NADP; Nitrates; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Superoxide Dismutase | 1999 |
L-arginine modulates aggregation and intracellular cyclic 3,5-guanosine monophosphate levels in human platelets: direct effect and interplay with antioxidative thiol agent.
Topics: Acetylcysteine; Antioxidants; Arginine; Blood Platelets; Drug Interactions; Enzyme Inhibitors; Free Radical Scavengers; Guanosine Monophosphate; Humans; Nitric Oxide; omega-N-Methylarginine; Platelet Aggregation; Platelet Aggregation Inhibitors | 1999 |
Substrate and inhibitor for nitric oxide synthase during peritoneal dialysis in rabbits.
Topics: Albumins; Animals; Arginine; Biological Transport; Creatinine; Dialysis Solutions; Enzyme Inhibitors; Female; Glucose; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Peritoneal Dialysis; Peritoneum; Permeability; Rabbits; Urea | 1999 |
Human NK cells express endothelial nitric oxide synthase, and nitric oxide protects them from activation-induced cell death by regulating expression of TNF-alpha.
Topics: Adjuvants, Immunologic; Apoptosis; Arginine; Cell Line; Coculture Techniques; Culture Media; Dose-Response Relationship, Immunologic; Endothelium, Vascular; Humans; Killer Cells, Natural; Lymphocyte Activation; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Penicillamine; Receptors, IgG; RNA, Messenger; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1999 |
Endothelin-1 modulates intrahepatic resistance in a rat model of noncirrhotic portal hypertension.
Topics: Animals; Arginine; Endothelin-1; Hypertension, Portal; In Vitro Techniques; Male; Nitric Oxide; omega-N-Methylarginine; Peptides, Cyclic; Perfusion; Rats; Rats, Inbred F344; Vascular Resistance; Vasoconstriction | 1999 |
Cytokine-induced venodilatation in humans in vivo: eNOS masquerading as iNOS.
Topics: Adult; Arginine; Biopterins; Bradykinin; Endothelium, Vascular; Enzyme Inhibitors; Female; Gene Expression; Guanidines; Humans; Interleukin-1; Interleukin-6; Intracellular Signaling Peptides and Proteins; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Norepinephrine; omega-N-Methylarginine; Proteins; Reverse Transcriptase Polymerase Chain Reaction; Shock, Septic; Tumor Necrosis Factor-alpha; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 1999 |
Nitric oxide modulates the gastrointestinal plasma extravasation following intraabdominal surgical manipulation in rats.
Topics: Anesthesia; Animals; Arginine; Capillary Permeability; Digestive System; Digestive System Surgical Procedures; Drug Interactions; Endothelium; Glutathione; Laparotomy; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroso Compounds; omega-N-Methylarginine; Rats; Rats, Wistar | 1999 |
Exhaled nitric oxide does not provide a marker of vascular endothelial function in healthy humans.
Topics: Administration, Inhalation; Adult; Analysis of Variance; Arginine; Biomarkers; Blood Pressure; Endothelium, Vascular; Enzyme Inhibitors; Heart Rate; Hemodynamics; Humans; Infusions, Intravenous; Luminescent Measurements; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine | 1999 |
Production of nitric oxide in mouse peritoneal macrophages after priming with interferon-gamma by the stem of Sinomenium acutum.
Topics: Animals; Antibodies; Arginine; Cells, Cultured; Interferon-gamma; Macrophages, Peritoneal; Mice; Neutralization Tests; Nitrates; Nitric Oxide; Nitrites; omega-N-Methylarginine; Plant Extracts; Protein Kinase Inhibitors; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1999 |
Hepatocyte growth factor regulates human trophoblast motility and invasion: a role for nitric oxide.
Topics: Arginine; Cell Division; Cell Line; Cell Movement; Cell Size; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Induction; Female; Fibrin; Hepatocyte Growth Factor; Humans; Integrins; Interleukin-1; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; RNA, Messenger; Transfection; Trophoblasts; Tumor Necrosis Factor-alpha | 1999 |
NO mediates postjunctional inhibitory effect of neurogenic ACh in guinea pig small intestinal microcirculation.
Topics: Acetylcholine; Animals; Arginine; Arterioles; Electric Stimulation; Endothelium, Vascular; Enzyme Inhibitors; Female; Ganglia; Guinea Pigs; Intestine, Small; Iontophoresis; Male; Microcirculation; Nervous System; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Pirenzepine; Vasoconstriction | 1999 |
The effects of alterations in nitric oxide levels in the paraventricular nucleus on copulatory behavior and reflexive erections in male rats.
Topics: Animals; Arginine; Female; Male; Nitric Oxide; omega-N-Methylarginine; Paraventricular Hypothalamic Nucleus; Penile Erection; Rats; Rats, Wistar; Reflex; Sexual Behavior, Animal | 1999 |
Expression of citrulline-nitric oxide cycle in lipopolysaccharide and cytokine-stimulated rat astroglioma C6 cells.
Topics: Animals; Arginine; Astrocytoma; Citrulline; Cytokines; Enzyme Induction; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Interferon-gamma; Kinetics; Lipopolysaccharides; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Rats; Recombinant Proteins; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1999 |
Cardioprotective activity of endogenous and exogenous nitric oxide on ischaemia reperfusion injury in isolated guinea pig hearts.
Topics: Animals; Arginine; Arrhythmias, Cardiac; Calcium; Cell Degranulation; Coronary Vessels; Enzyme Inhibitors; Guinea Pigs; Histamine Release; Image Processing, Computer-Assisted; In Vitro Techniques; Lipid Peroxidation; Male; Mast Cells; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Reperfusion Injury; Vasodilator Agents | 1999 |
Effects of dietary L-arginine on the reactivity of canine coronary arteries.
Topics: Adrenergic alpha-Agonists; Animals; Arginine; Brimonidine Tartrate; Calcimycin; Coronary Vessels; Dietary Supplements; Dinoprost; Dogs; Endothelium, Vascular; Ionophores; Male; Muscle Contraction; Muscle, Smooth; Nitric Oxide; omega-N-Methylarginine; Quinoxalines; Tetraethylammonium | 1999 |
[Role of L-arginine--endogenous NOS inhibitors--endothelin-1 pathway for the vascular remodelling].
Topics: Animals; Arginine; Carotid Arteries; Cell Division; Endothelin-1; Endothelium, Vascular; Enzyme Inhibitors; Male; Muscle, Smooth, Vascular; Neovascularization, Physiologic; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rabbits; Regeneration | 1999 |
A microtiter-plate assay of nitric oxide synthase activity.
Topics: Animals; Arginine; Enzyme Inhibitors; Humans; Isoenzymes; Methemoglobin; Molecular Biology; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Oxyhemoglobins; Recombinant Proteins; Spectrophotometry | 1999 |
The role of nitric oxide in testicular ischemia-reperfusion injury.
Topics: Animals; Arginine; Enzyme Inhibitors; Male; Malondialdehyde; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Spermatic Cord Torsion; Testis | 2000 |
Nitric oxide affects angiotensin II pressor response: possible mechanism of attenuated pressor response during pregnancy and etiology of pregnancy-induced hypertension.
Topics: Angiotensin II; Animals; Arginine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enzyme Inhibitors; Female; Hypertension; Injections, Intraperitoneal; Nitric Oxide; omega-N-Methylarginine; Pregnancy; Pregnancy Complications, Cardiovascular; Pressoreceptors; Probability; Rats; Rats, Wistar; Reference Values; Sensitivity and Specificity; Software; Vasoconstrictor Agents | 2000 |
Enhanced coronary vasoconstriction to oxidative stress product, 8-epi-prostaglandinF2 alpha, in experimental hypercholesterolemia.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Analysis of Variance; Animals; Arginine; Arteries; Bridged Bicyclo Compounds, Heterocyclic; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Coronary Vessels; Dinoprost; Dinoprostone; Endothelium, Vascular; Enzyme Inhibitors; Fatty Acids, Unsaturated; Female; Hydrazines; Hypercholesterolemia; Immunohistochemistry; In Vitro Techniques; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitro Compounds; omega-N-Methylarginine; Oxidative Stress; Random Allocation; Swine; Thromboxane A2; Vasoconstriction; Vasoconstrictor Agents | 1999 |
Changes in extracellular pH mediate the chronotropic responses to L-arginine.
Topics: Analysis of Variance; Animals; Arginine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Erythrocytes; Extracellular Space; Guinea Pigs; Heart Rate; Hydrogen-Ion Concentration; Isomerism; Lysine; Nitric Oxide Synthase; omega-N-Methylarginine; Perfusion; Stimulation, Chemical | 1999 |
Sympathectomy potentiates the vasoconstrictor response to nitric oxide synthase inhibition in humans.
Topics: Adult; Arginine; Case-Control Studies; Enzyme Inhibitors; Female; Forearm; Humans; Hyperhidrosis; Leg; Male; Nitric Oxide Synthase; omega-N-Methylarginine; Phenylephrine; Regional Blood Flow; Sympathectomy; Vascular Resistance; Vasoconstrictor Agents | 1999 |
Chemical hypoxia-induced increases in dopamine D1A receptor mRNA in renal epithelial cells are mediated by nitric oxide.
Topics: Animals; Arginine; Cyclic GMP; Deoxyglucose; Enzyme Inhibitors; Epithelial Cells; Hypoxia; Kidney; LLC-PK1 Cells; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; omega-N-Methylarginine; Receptors, Dopamine D1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium Cyanide; Swine | 2000 |
delta-opioid receptors and nitric oxide mediate the analgesic effect of Crotalus durissus terrificus snake venom.
Topics: Analgesics, Non-Narcotic; Animals; Arginine; Carrageenan; Crotalid Venoms; Cyclic GMP; Edema; Enzyme Inhibitors; Hyperalgesia; Male; Methylene Blue; Motor Activity; Narcotic Antagonists; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2000 |
Nitric oxide synthesised from L-arginine mediates endothelium dependent dilatation in human veins in vivo.
Topics: Arginine; Bibliometrics; Endothelium, Vascular; History, 20th Century; Humans; Nitric Oxide; omega-N-Methylarginine; Publishing; Shock; Veins | 2000 |
Nitric oxide regulates nucleoside transport in activated B lymphocytes.
Topics: Arginine; B-Lymphocytes; Biological Transport; Carrier Proteins; Equilibrative Nucleoside Transporter 1; Gene Expression Regulation; Humans; Lymphocyte Activation; Lysine; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroso Compounds; Nucleoside Transport Proteins; Nucleosides; omega-N-Methylarginine; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2000 |
Interaction of L-arginine and phosphodiesterase inhibitors in vasodilation of the porcine internal mammary artery.
Topics: Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Drug Synergism; Mammary Arteries; omega-N-Methylarginine; Phosphodiesterase Inhibitors; Swine; Vasodilation | 2000 |
[Experimental study on the effect of nitric oxide on cochleas of guinea pigs].
Topics: Action Potentials; Animals; Arginine; Cochlea; Cochlear Microphonic Potentials; Guinea Pigs; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Random Allocation | 1997 |
Expression of a functional inducible nitric oxide synthase in hairy cell leukaemia and ESKOL cell line.
Topics: Amidines; Antibodies, Monoclonal; Apoptosis; Arginine; Benzylamines; Blotting, Western; Enzyme Induction; Enzyme Inhibitors; Fluorescent Dyes; Gene Expression Regulation, Leukemic; Humans; Leukemia, Hairy Cell; Microscopy, Fluorescence; Neoplasm Proteins; Neoplastic Stem Cells; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; omega-N-Methylarginine; Receptors, IgE; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured | 2000 |
Effect of L-arginine-nitric oxide system on the metabolism of essential fatty acids in chemical-induced diabetes mellitus.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arginine; Delta-5 Fatty Acid Desaturase; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Fatty Acid Desaturases; Fatty Acids, Essential; gamma-Linolenic Acid; Linoleic Acid; Linoleoyl-CoA Desaturase; Lipid Peroxides; Male; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Phospholipids; Rats; Rats, Wistar | 2000 |
Role of nitric oxide on insulin induced seizures in mice.
Topics: Animals; Arginine; Dose-Response Relationship, Drug; Hypoglycemia; Insulin; Male; Mice; Mice, Inbred ICR; Nitric Oxide; Nitric Oxide Donors; omega-N-Methylarginine; Receptors, N-Methyl-D-Aspartate; Seizures | 1999 |
Mechanisms responsible for endothelial dysfunction associated with acute estrogen deprivation in normotensive women.
Topics: Acetylcholine; Adult; Arginine; Ascorbic Acid; Blood Pressure; Cardiovascular Agents; Endothelium, Vascular; Enzyme Inhibitors; Estrogen Replacement Therapy; Estrogens; Female; Forearm; Humans; Indomethacin; Leiomyoma; Middle Aged; omega-N-Methylarginine; Ovariectomy; Postoperative Period; Reference Values; Regional Blood Flow; Uterine Neoplasms; Vasodilation; Vasodilator Agents | 2000 |
Effects of a nitric oxide synthase inhibitor on pressor response to angiotensin II in conscious rats.
Topics: Acetylglucosaminidase; Angiotensin II; Animals; Arginine; Blood Pressure; Consciousness; Dose-Response Relationship, Drug; Drug Synergism; Endothelium, Vascular; Enzyme Inhibitors; Female; Infusions, Parenteral; Injections, Intravenous; Natriuresis; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Proteinuria; Rats; Rats, Wistar | 1998 |
Characterization of L-arginine transporters in rat renal inner medullary collecting duct.
Topics: Amino Acid Transport Systems; Animals; Arginine; beta-Alanine; Biological Transport; Carrier Proteins; Cations; Citrulline; Enzyme Inhibitors; Gene Expression; Homeostasis; Kidney Medulla; Kidney Tubules, Collecting; Lysine; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Ornithine; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substrate Specificity; Tritium; Water-Electrolyte Balance | 2000 |
[The role of nitric oxide in changes in the oxygen consumption and the oxygen cost of the work of the cardiac muscle].
Topics: Animals; Arginine; Coronary Vessels; Endothelium, Vascular; Energy Metabolism; Enzyme Inhibitors; Guinea Pigs; Heart; In Vitro Techniques; Myocardial Contraction; Myocardium; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Oxygen Consumption; Vasodilator Agents | 2000 |
L-NAME causes antinociception by stimulation of the arginine-NO-cGMP pathway.
Topics: Analgesics; Animals; Arginine; Carrageenan; Cyclic GMP; Dinoprostone; Hyperalgesia; Male; Methylene Blue; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Oxadiazoles; Phosphodiesterase Inhibitors; Phthalazines; Quinoxalines; Rats; Rats, Wistar; Signal Transduction | 2000 |
Critical dependence of the NO-mediated component of cyclic AMP-induced vasorelaxation on extracellular L-arginine in pulmonary arteries of the rat.
Topics: Animals; Arginine; Cyclic AMP; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Isoproterenol; Lysine; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Pulmonary Artery; Rats; Rats, Wistar; Vasodilation | 2000 |
Measurement of NOS activity by conversion of radiolabeled arginine to citrulline using ion-exchange separation.
Topics: Animals; Arginine; Carbon Radioisotopes; Cell Fractionation; Chromatography, Ion Exchange; Citrulline; Enzyme Inhibitors; Nitric Oxide Synthase; omega-N-Methylarginine; Radioisotope Dilution Technique; Tritium | 1998 |
Use of arginine analogs as inhibitors of nitric oxide synthase in rat-aortic rings.
Topics: Animals; Aorta, Thoracic; Arginine; Enzyme Inhibitors; Guanidines; In Vitro Techniques; Kinetics; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroarginine; omega-N-Methylarginine; Ornithine; Phenylephrine; Rats; Rats, Wistar | 1998 |
Nitric oxide induces apoptosis in the human corpus luteum in vitro.
Topics: Adult; Apoptosis; Arginine; Aromatase; Chorionic Gonadotropin; Corpus Luteum; Enzyme Inhibitors; Estradiol; Female; Humans; In Situ Nick-End Labeling; In Vitro Techniques; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Proto-Oncogene Proteins c-bcl-2 | 2000 |
Regulation of ciliary beat frequency by the nitric oxide-cyclic guanosine monophosphate signaling pathway in rat airway epithelial cells.
Topics: Alkaloids; Animals; Arginine; Carbazoles; Cells, Cultured; Cilia; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Glutathione; Indoles; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; omega-N-Methylarginine; Oxadiazoles; Purinones; Quinoxalines; Rats; S-Nitrosoglutathione; Signal Transduction; Trachea | 2000 |
Endogenous nitric oxide synthase inhibitors are responsible for the L-arginine paradox.
Topics: Animals; Arginine; Binding, Competitive; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Meta-Analysis as Topic; Models, Biological; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Thermodynamics | 2000 |
Intracarotid infusion of the nitric oxide synthase inhibitor, L-NMMA, modestly decreases cerebral blood flow in human subjects.
Topics: Adult; Aged; Arginine; Carotid Arteries; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Humans; Infusions, Intra-Arterial; Male; Middle Aged; Nitric Oxide Synthase; omega-N-Methylarginine | 2000 |
Antiproliferative effect of L-NAME on rat vascular smooth muscle cells.
Topics: Animals; Arginine; Becaplermin; Cell Division; Culture Media; DNA; Drug Interactions; Enzyme Inhibitors; Growth Inhibitors; Guanidines; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phosphorylation; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Rats; Rats, Sprague-Dawley; Thymidine | 2000 |
Exogenous hyaluronidase induces release of nitric oxide from the coronary endothelium.
Topics: Analysis of Variance; Animals; Arginine; Coronary Vessels; Dogs; Endothelium, Vascular; Enzyme Inhibitors; Hemoglobins; Hyaluronoglucosaminidase; Nitric Oxide; omega-N-Methylarginine; Prostaglandins F; Vasodilator Agents | 2000 |
The modulation of oxygen radical production by nitric oxide in mitochondria.
Topics: Animals; Arginine; Cytochrome b Group; Dose-Response Relationship, Drug; Electron Transport; Electron Transport Complex IV; Enzyme Inhibitors; Free Radicals; Glutathione; Hydrogen Peroxide; Mitochondria, Liver; Models, Chemical; Myoglobin; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitroso Compounds; omega-N-Methylarginine; Oxygen; Oxygen Consumption; Rats; Rats, Wistar; S-Nitrosoglutathione | 2001 |
Induction of inducible nitric oxide synthase by ginsenosides in cultured porcine endothelial cells.
Topics: Animals; Aorta; Arginine; Calcium; Cells, Cultured; Drug Combinations; Endothelium, Vascular; Enzyme Induction; Enzyme Inhibitors; Ginsenosides; Immunohistochemistry; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Saponins; Swine | 2000 |
Influence of insulin on the metabolism of glucose in uteri isolated from ovariectomized and non ovariectomized underfed rats.
Topics: Amenorrhea; Animals; Arachidonic Acid; Arginine; Aspirin; Diestrus; Dose-Response Relationship, Drug; Eicosanoids; Energy Metabolism; Enzyme Inhibitors; Female; Food Deprivation; Glucose; Hemoglobins; Insulin; Myometrium; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; omega-N-Methylarginine; Ovariectomy; Rats; Rats, Wistar; Uterus | 2000 |
Tacrolimus in acute renal failure: does L-arginine-infusion prevent changes in renal hemodynamics?
Topics: Acute Kidney Injury; Animals; Arginine; Blood Pressure; Calcineurin Inhibitors; Constriction; Diuresis; Enzyme Inhibitors; Female; Glomerular Filtration Rate; Immunosuppressive Agents; Ischemia; Kidney; Kidney Glomerulus; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Renal Artery; Renal Circulation; Tacrolimus; Vascular Resistance; Vasoconstriction | 2000 |
In vivo on-line detection of no distribution in endotoxin-treated mice by l-band ESR.
Topics: Animals; Arginine; Chelating Agents; Ditiocarb; Electron Spin Resonance Spectroscopy; Endotoxins; Enzyme Inhibitors; Female; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Transgenic; Models, Biological; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Protein Isoforms; Sorbitol; Spin Labels; Thiocarbamates; Time Factors | 2000 |
Nitric oxide generation by hemocytes of the mussel Mytilus galloprovincialis.
Topics: Animals; Arginine; Bivalvia; Citrulline; Enzyme Inhibitors; Hemocytes; Latex; Luminescent Measurements; Microspheres; NADPH Oxidases; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Ornithine; Phagocytosis; Superoxide Dismutase; Superoxides | 2001 |
Dose- and time-dependence of radiation-induced nitric oxide formation in mice as quantified with electron paramagnetic resonance.
Topics: Animals; Arginine; Dose-Response Relationship, Radiation; Electron Spin Resonance Spectroscopy; Enzyme Induction; Enzyme Inhibitors; Female; Inflammation; Liver; Mice; Mice, Inbred ICR; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Radiation Dosage; Radiation Injuries, Experimental; Sorbitol; Spin Labels; Thiocarbamates; Time Factors; Whole-Body Irradiation | 2001 |
NO/cGMP signaling modulates regulation of Na+-K+-ATPase activity by angiotensin II in rat proximal tubules.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arginine; Calcium; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Intracellular Membranes; Kidney Tubules, Proximal; Male; Nitric Oxide; omega-N-Methylarginine; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Signal Transduction; Sodium-Potassium-Exchanging ATPase; Solubility | 2001 |
Beneficial effects of nitric oxide synthase inhibition on the recovery of neurological function after spinal cord injury in rats.
Topics: Animals; Arginine; Blood Pressure; Enzyme Inhibitors; Evoked Potentials, Motor; Immunohistochemistry; Male; Motor Activity; Nervous System; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Wistar; Spinal Cord; Spinal Cord Injuries; Stereoisomerism | 2001 |
Nitric oxide in unilateral ureteral obstruction: effect on regional renal blood flow.
Topics: Animals; Arginine; Enzyme Inhibitors; Kidney Tubules; Male; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroprusside; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Renal Circulation; Ureteral Obstruction | 2001 |
Involvement of the perferryl complex of nitric oxide synthase in the catalysis of secondary free radical formation.
Topics: Arginine; Catalysis; Cell Line; Electron Spin Resonance Spectroscopy; Ethanol; Free Radicals; Iron; Models, Chemical; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; omega-N-Methylarginine; Signal Transduction; Spin Trapping; Superoxides; Transfection | 2001 |
Regulation of cardiac calcium current by NO and cGMP-modulating agents.
Topics: Adenine; Animals; Arginine; Biological Transport; Calcium Channels, L-Type; Carbachol; Cholinergic Agonists; Cyclic GMP; Cyclic N-Oxides; Enzyme Inhibitors; Exonucleases; Free Radical Scavengers; Guinea Pigs; Imidazoles; In Vitro Techniques; Myocardium; Nitric Oxide; omega-N-Methylarginine; Orchiectomy; Oxadiazoles; Quinoxalines; Receptors, Muscarinic | 2001 |
Nitric oxide production by murine spleen cells stimulated with Porphyromonas gingivalis-derived lipopolysaccharide.
Topics: Animals; Antineoplastic Agents; Arginine; Cells, Cultured; Enzyme Inhibitors; Female; Interferon-gamma; Lipopolysaccharides; Mice; Mice, Inbred BALB C; Nitric Oxide; omega-N-Methylarginine; Porphyromonas gingivalis; Salmonella typhi; Spleen | 2000 |
Nitric oxide modulates cardiac performance in the heart of Anguilla anguilla.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Anguilla; Animals; Arginine; Atropine; Detergents; Enzyme Inhibitors; Female; Free Radical Scavengers; Heart; Heart Rate; Hemodynamics; In Vitro Techniques; Male; Molsidomine; Muscarinic Antagonists; Myocardial Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Octoxynol; omega-N-Methylarginine; Ornithine; Oxadiazoles; Parasympatholytics; Pirenzepine; Quinoxalines; Superoxide Dismutase | 2001 |
L-arginine effects on Na+ transport in M-1 mouse cortical collecting duct cells--a cationic amino acid absorbing epithelium.
Topics: Amiloride; Animals; Arginine; Cell Line; Cell Polarity; Diuretics; Electrophysiology; Enzyme Inhibitors; Epithelial Cells; Histidine; Ion Transport; Kidney Tubules, Collecting; Lysine; Mice; omega-N-Methylarginine; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Sodium; Urothelium | 2001 |
Role of nitric oxide in the control of cerebral microcirculation under physiological and pathological conditions.
Topics: Animals; Antioxidants; Arginine; Arterioles; Cerebral Revascularization; Cerebrovascular Circulation; Collateral Circulation; Dose-Response Relationship, Drug; Humans; Male; Microcirculation; Moyamoya Disease; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Vasoconstrictor Agents; Vasomotor System | 2000 |
Methylation of histone H3 by coactivator-associated arginine methyltransferase 1.
Topics: Amino Acid Sequence; Amino Acids; Animals; Arginine; Catalysis; Cattle; Chickens; Chromatography, High Pressure Liquid; Enzyme Activation; Histones; Kinetics; Methylation; Molecular Sequence Data; Oligopeptides; omega-N-Methylarginine; Protein-Arginine N-Methyltransferases; Recombinant Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity | 2001 |
Uremic levels of urea inhibit L-arginine transport in cultured endothelial cells.
Topics: Animals; Aorta; Arginine; Biological Transport; Capillaries; Cattle; Cells, Cultured; Endothelium, Vascular; Enzyme Inhibitors; Humans; Hypertension, Renal; Kidney Failure, Chronic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Urea; Uremia | 2001 |
Tetrahydrobiopterin: a critical cofactor for eNOS and a strategy in the treatment of endothelial dysfunction?
Topics: Animals; Arginine; Biopterins; Cardiovascular Diseases; Clinical Trials as Topic; Coronary Vessels; Dogs; Endothelium, Vascular; Enzyme Inhibitors; Histamine; Humans; Hypercholesterolemia; In Vitro Techniques; Infusions, Intra-Arterial; Ionophores; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Pteridines; Pterins; Reactive Oxygen Species; Species Specificity; Substance P; Swine; Vasoconstrictor Agents; Vasodilator Agents | 2001 |
Nitric oxide synthase in porcine heart mitochondria: evidence for low physiological activity.
Topics: Animals; Arginine; Cell Respiration; Citrulline; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Mitochondria, Heart; Mitochondria, Liver; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Oxidative Phosphorylation; Oxygen Consumption; Swine | 2001 |
Metabolism of S-nitrosoglutathione in intact mitochondria.
Topics: Animals; Arginine; Glutathione; Glutathione Disulfide; Hydrogen Peroxide; In Vitro Techniques; Kinetics; Mitochondria, Liver; Nitric Oxide; Nitroso Compounds; omega-N-Methylarginine; Oxygen Consumption; Rats; Rats, Wistar; S-Nitrosoglutathione; Signal Transduction | 2001 |
Short-acting calcium antagonist clevidipine protects against reperfusion injury via local nitric oxide-related mechanisms in the jeopardised myocardium.
Topics: Analysis of Variance; Animals; Arginine; Calcium Channel Blockers; Endothelium, Vascular; Enzyme Inhibitors; Female; Male; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Pyridines; Random Allocation; Substance P; Swine; Vascular Resistance | 2001 |
Nitric oxide formation in macrophages detected by spin trapping with iron-dithiocarbamate complex: effect of purified flavonoids and plant extracts.
Topics: Animals; Arginine; Cell Line; Ferrous Compounds; Flavonoids; Kinetics; Lysine; Macrophages; Mice; Nitric Oxide; omega-N-Methylarginine; Plant Extracts; Spin Labels; Superoxide Dismutase; Thiocarbamates | 2001 |
The human internal thoracic artery releases more nitric oxide in response to vascular endothelial growth factor than the human saphenous vein.
Topics: Analysis of Variance; Arginine; Coronary Artery Bypass; Endothelial Growth Factors; Enzyme Inhibitors; Female; Humans; Immunoenzyme Techniques; Lymphokines; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Saphenous Vein; Thoracic Arteries; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2001 |
Expression of nitric oxide synthases and effects of L-arginine and L-NMMA on nitric oxide production and fluid transport in collagenous colitis.
Topics: Adult; Aged; Arginine; Blotting, Western; Body Fluids; Case-Control Studies; Colitis, Ulcerative; Confidence Intervals; Female; Humans; Intestinal Absorption; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Statistics, Nonparametric; Tyrosine; Up-Regulation | 2001 |
Mitochondrial control of inducible nitric oxide production in stimulated RAW 264.7 macrophages.
Topics: Animals; Antimycin A; Arginine; Cell Line; Drug Synergism; Electron Spin Resonance Spectroscopy; Electron Transport; Electron Transport Complex I; Electron Transport Complex III; Enzyme Inhibitors; Glucose; Macrophage Activation; Macrophages; Membrane Potentials; Mice; Mitochondria; NADH, NADPH Oxidoreductases; NADP; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Rotenone; Spin Trapping; Superoxide Dismutase | 2001 |
Effects of the reactive oxygen species hydrogen peroxide and hypochlorite on endothelial nitric oxide production.
Topics: Adenosine Diphosphate; Animals; Arginine; Bradykinin; Calcimycin; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Hydrogen Peroxide; Hypochlorous Acid; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroprusside; omega-N-Methylarginine; Oxidants; Swine | 2001 |
Nitric oxide modulates sympathoexcitatory cardiac-cardiovascular reflexes elicited by bradykinin.
Topics: Animals; Arginine; Baroreflex; Blood Pressure; Bradykinin; Cats; Denervation; Enzyme Inhibitors; Female; Heart Rate; Indazoles; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; omega-N-Methylarginine; Sympathetic Nervous System; Vagotomy | 2001 |
The nitric oxide pathway is amplified in venular vs arteriolar cultured rat mesenteric endothelial cells.
Topics: Animals; Arginine; Arterioles; Biological Transport; Blotting, Western; Cells, Cultured; Endothelium, Vascular; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Splanchnic Circulation; Venules | 2001 |
Effects of nebivolol on human platelet aggregation.
Topics: Adenosine Diphosphate; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Arginine; Benzopyrans; Blood Platelets; Carbazoles; Carvedilol; Collagen; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Ethanolamines; Humans; Male; Nebivolol; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Aggregation; Platelet Aggregation Inhibitors; Propanolamines; Propranolol; Vasodilator Agents | 2001 |
Acute administration of L-arginine does not improve arterial endothelial function in chronic renal failure.
Topics: Adult; Arginine; Arteries; Brachial Artery; Endothelium, Vascular; Enzyme Inhibitors; Humans; Kidney Failure, Chronic; Middle Aged; Nitric Oxide Synthase; omega-N-Methylarginine; Radial Artery; Regional Blood Flow; Renal Dialysis; Vascular Resistance; Vasodilation | 2001 |
Citrulline is not the major product using the standard "NOS activity" assay on renal cortical homogenates.
Topics: Animals; Antioxidants; Arginine; Biopterins; Calcium; Carbon Radioisotopes; Chelating Agents; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Citrulline; Egtazic Acid; Enzyme Inhibitors; Female; Guanidines; Humans; Kidney Cortex; Male; Mice; Mice, Inbred Strains; NADP; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Placenta; Rats; Rats, Long-Evans; Tritium | 2002 |
Effects of nitric oxide and GABA interaction within ventrolateral medulla on cardiovascular responses during static muscle contraction.
Topics: Afferent Pathways; Animals; Arginine; Cardiovascular Physiological Phenomena; Electric Stimulation; Enzyme Inhibitors; Extracellular Space; Female; gamma-Aminobutyric Acid; Medulla Oblongata; Microdialysis; Muscle Contraction; Neural Conduction; Neural Inhibition; Neurons; Nitric Oxide; omega-N-Methylarginine; Physical Exertion; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Tibial Nerve | 2001 |
Activation of cardiac endothelium as a compensatory component in endotoxin-induced cardiomyopathy: role of endothelin, prostaglandins, and nitric oxide.
Topics: Animals; Arginine; Binding, Competitive; Cardiomyopathies; Cyclooxygenase 2; Dose-Response Relationship, Drug; Endothelin-1; Endothelins; Endothelium, Vascular; Enzyme Inhibitors; Hemodynamics; Immunohistochemistry; Isoenzymes; Lipopolysaccharides; Male; Muscle Contraction; Myocardial Contraction; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Papillary Muscles; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rabbits; Receptor, Endothelin A; Receptors, Endothelin; Superoxide Dismutase; Time Factors | 2001 |
Analysis of protein arginine methylation and protein arginine-methyltransferase activity.
Topics: Animals; Antibodies, Monoclonal; Arginine; DNA-Binding Proteins; Enzyme Activation; Humans; Immunoblotting; Methylation; Mice; omega-N-Methylarginine; Precipitin Tests; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases; Proteins; Signal Transduction; STAT1 Transcription Factor; Trans-Activators; Tumor Cells, Cultured | 2001 |
[Effects of relative imbalance between endothlin-1 and nitric oxide on pathogenesis of the ascaris-induced asthma in dogs].
Topics: Animals; Arginine; Ascaris; Asthma; Disease Models, Animal; Dogs; Endothelin-1; Enzyme Inhibitors; Female; Infusions, Intravenous; Male; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine | 1999 |
The effect of nitric oxide on acetylcholine release in the rabbit bladder.
Topics: Acetylcholine; Animals; Arginine; Atropine; Electric Stimulation; Enzyme Inhibitors; Female; In Vitro Techniques; Microdialysis; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Potassium Chloride; Rabbits; Urinary Bladder; Vasodilator Agents | 2001 |
Partial inhibition of nitric oxide synthesis in vivo does not inhibit glucose production in man.
Topics: Adult; Arginine; Cross-Over Studies; Endocrine Glands; Enzyme Inhibitors; Glucose; Hemodynamics; Humans; Infusions, Intravenous; Male; Nitrates; Nitric Oxide; omega-N-Methylarginine | 2002 |
Endogenous nitric oxide synthase inhibitors in endothelial cells, endothelin-1 within the vessel wall, and intimal hyperplasia in perimenopausal human uterine arteries.
Topics: Adult; Arginine; Arteries; Chromatography, High Pressure Liquid; Climacteric; Cyclic GMP; Endothelin-1; Endothelium, Vascular; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Female; Humans; Hyperplasia; In Vitro Techniques; Middle Aged; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Tunica Intima; Tunica Media; Uterus | 2002 |
Role of L-arginine/nitric oxide pathway in the antinociceptive activities of morphine and mepyramine in mice.
Topics: Abdomen; Analgesics, Opioid; Animals; Arginine; Benzoquinones; Drug Interactions; Enzyme Inhibitors; Histamine H1 Antagonists; Male; Mice; Morphine; Muscle Contraction; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Pain Measurement; Pyrilamine; Signal Transduction | 2001 |
[The role of nitric oxide in hyperdynamic circulation in portal hypertensive rats].
Topics: Animals; Arginine; Carbon Tetrachloride; Disease Models, Animal; Enzyme Inhibitors; Hemodynamics; Hypertension, Portal; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Portasystemic Shunt, Surgical; Rats; Rats, Sprague-Dawley | 1998 |
L-arginine rescues decreased erythropoietin gene expression by stimulating GATA-2 with L-NMMA.
Topics: Anemia; Animals; Arginine; Cell Hypoxia; Cells, Cultured; Cyclic GMP; DNA-Binding Proteins; Enzyme Inhibitors; Erythropoietin; GATA2 Transcription Factor; Gene Expression; Humans; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Oxygen; Promoter Regions, Genetic; RNA, Messenger; Transcription Factors; Uremia | 2002 |
Diesel particles increase phosphatidylcholine release through a NO pathway in alveolar type II cells.
Topics: Animals; Arginine; Cells, Cultured; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Male; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Penicillamine; Phosphatidylcholines; Pulmonary Alveoli; Pulmonary Surfactants; Rats; Rats, Sprague-Dawley; Specific Pathogen-Free Organisms; Vehicle Emissions | 2002 |
Accumulated endogenous NOS inhibitors, decreased NOS activity, and impaired cavernosal relaxation with ischemia.
Topics: Animals; Arginine; Calcium; Carbachol; Cholinergic Agonists; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Endothelium, Vascular; Enzyme Inhibitors; Iliac Artery; Impotence, Vasculogenic; In Vitro Techniques; Ischemia; Male; Nitric Oxide Synthase; omega-N-Methylarginine; Penis; Rabbits; Vasoconstrictor Agents; Vasodilator Agents | 2002 |
GATA suppresses erythropoietin gene expression through GATA site in mouse erythropoietin gene promoter.
Topics: Animals; Arginine; Binding Sites; Catalase; DNA-Binding Proteins; Down-Regulation; Erythroid-Specific DNA-Binding Factors; Erythropoietin; GATA2 Transcription Factor; GATA3 Transcription Factor; Hydrogen Peroxide; Mice; omega-N-Methylarginine; Promoter Regions, Genetic; Trans-Activators; Transcription Factors; Transfection; Tumor Cells, Cultured | 2002 |
Evaluation of basic performance and applicability of a newly developed in vivo nitric oxide sensor.
Topics: Acetylcholine; Animals; Antioxidants; Arginine; Biopterins; Calibration; Electrodes; Enzyme Inhibitors; Equipment Design; Nitric Oxide; Nitric Oxide Synthase; Nitroglycerin; omega-N-Methylarginine; Oxygen; Permeability; Rats; Rats, Inbred WKY; Vasodilator Agents | 2002 |
Endogenous methylarginines regulate neuronal nitric-oxide synthase and prevent excitotoxic injury.
Topics: Animals; Arginine; Cell Survival; Cells, Cultured; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; omega-N-Methylarginine; Rats | 2002 |
Nitric oxide synthase inhibitors affect nitric oxide synthesis in normoxic but not in ischemic organs during intestinal ischemia and early reperfusion.
Topics: Animals; Arginine; Disease Models, Animal; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Intestines; Liver; Lung; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2002 |
Down-regulation of spontaneous Epstein-Barr virus reactivation in the P3HR-1 cell line by L-arginine.
Topics: Arginine; Blotting, Northern; Blotting, Western; Cell Division; Cells, Cultured; DNA-Binding Proteins; Enzyme Inhibitors; Gene Expression; Herpesvirus 4, Human; Humans; Immediate-Early Proteins; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Trans-Activators; Viral Proteins | 2002 |
The production of nitric oxide in EL4 lymphoma cells overexpressing growth hormone.
Topics: Animals; Arginine; Carbocyanines; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cells, Cultured; Dose-Response Relationship, Drug; Drug Resistance; Growth Hormone; Immune System; Lymphocytes; Lymphoma; Membrane Potentials; Methyl Methanesulfonate; Mice; Mitochondria; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Protein Transport; Receptors, Somatotropin; Stress, Physiological | 2003 |
Cardiac performance in Salmo salar with infectious salmon anaemia (ISA): putative role of nitric oxide.
Topics: Animals; Arginine; Enzyme Induction; Enzyme Inhibitors; Fish Diseases; Heart; Lysine; Myocardial Contraction; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Orthomyxoviridae; Orthomyxoviridae Infections; Salmo salar | 2002 |
Influence of nitric oxide on neurogenic contraction and relaxation of the human gastroepiploic artery.
Topics: Aged; Aged, 80 and over; Anesthetics, Local; Arginine; Autonomic Nervous System; Endothelium, Vascular; Enzyme Inhibitors; Female; Gastroepiploic Artery; Humans; In Vitro Techniques; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Tetrodotoxin; Vasoconstriction; Vasodilation | 2003 |
Platelet-activating factor synthesis by neutrophils, monocytes, and endothelial cells is modulated by nitric oxide production.
Topics: Adult; Arginine; Cells, Cultured; Cyclic GMP; Drug Synergism; Endothelium, Vascular; Enzyme Inhibitors; Humans; Lipopolysaccharides; Monocytes; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Platelet Activating Factor; Stereoisomerism; Tumor Necrosis Factor-alpha | 2003 |
Hepatocellular dysfunction induced by nitric oxide production in hepatocytes isolated from rats with sepsis.
Topics: Adenosine Triphosphate; Animals; Arginine; Cecum; Disease Models, Animal; Enzyme Inhibitors; Hepatocytes; Humans; Interleukin-1; Intestinal Perforation; Ketone Bodies; Ligation; Liver Diseases; Male; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Wistar; Recombinant Proteins; Systemic Inflammatory Response Syndrome | 2003 |
Regulation of human cutaneous circulation evaluated by laser Doppler flowmetry, iontophoresis, and spectral analysis: importance of nitric oxide and prostaglandines.
Topics: Acetylcholine; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Aspirin; Cyclooxygenase Inhibitors; Endothelium; Female; Humans; Iontophoresis; Laser-Doppler Flowmetry; Male; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Oscillometry; Prostaglandins; Regional Blood Flow; Signal Transduction; Skin; Skin Physiological Phenomena; Temperature; Time Factors; Vasodilation | 2003 |
Opposite nociceptive effects of the arginine/NO/cGMP pathway stimulation in dermal and subcutaneous tissues.
Topics: Animals; Arginine; Bucladesine; Cyclic GMP; Dermis; Dinoprostone; Dose-Response Relationship, Drug; Hyperalgesia; Injections, Subcutaneous; Male; Molsidomine; Nitric Oxide; Nociceptors; omega-N-Methylarginine; Oxadiazoles; Pain Measurement; Quinoxalines; Rats; Rats, Wistar; Subcutaneous Tissue; Time Factors | 2003 |
Vaccinia virus-induced inhibition of nitric oxide production.
Topics: Animals; Arginine; Cell Line; Cell Survival; Enzyme Inhibitors; Interferon-gamma; Interleukin-1; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; omega-N-Methylarginine; Tumor Necrosis Factor-alpha; Ultraviolet Rays; Vaccinia virus | 2003 |
Release of nitric oxide in the central nervous system mediates tonic and phasic contraction of the cat lower oesophageal sphincter.
Topics: Animals; Arginine; Cats; Central Nervous System; Deglutition; Enzyme Inhibitors; Esophagogastric Junction; Female; Injections, Intraventricular; Male; Muscle Contraction; Muscle Relaxation; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Peristalsis; Physical Stimulation; Stereoisomerism | 2003 |
Vitamin C augments the renal response to L-arginine in smokers.
Topics: Adolescent; Adult; Antioxidants; Arginine; Ascorbic Acid; Blood Pressure; Drug Synergism; Heart Rate; Humans; Infusions, Intravenous; Kidney; Male; omega-N-Methylarginine; Regional Blood Flow; Smoking; Vasodilation | 2003 |
Roles of accumulated endogenous nitric oxide synthase inhibitors and decreased nitric oxide synthase activity for impaired trigonal relaxation with ischemia.
Topics: Animals; Arginine; Electric Stimulation; Ischemia; Male; Muscle Relaxation; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Rabbits; Urinary Bladder | 2003 |
Neuropeptide Y enhances permeability across a rat aortic endothelial cell monolayer.
Topics: Animals; Anti-Anxiety Agents; Aorta; Arginine; Bradykinin; Bradykinin B2 Receptor Antagonists; Capillary Permeability; Cells, Cultured; Cyclic AMP; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Histamine; Indomethacin; Male; Neuropeptide Y; Nitric Oxide; omega-N-Methylarginine; Peptide Fragments; Peptide YY; Rats; Rats, Wistar; Receptors, Neuropeptide Y; Receptors, Vascular Endothelial Growth Factor; Vascular Endothelial Growth Factor A | 2004 |
A novel antioxidant, EPC-K1, stimulates endothelial nitric oxide production and scavenges hydroxyl radicals.
Topics: Animals; Antioxidants; Arginine; Ascorbic Acid; Coronary Vessels; Dinoprost; Dogs; Endothelium, Vascular; Female; Free Radical Scavengers; Hydroxyl Radical; Male; Models, Animal; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Vasodilation; Vitamin E | 2003 |
Spectrophotometric and steady-state kinetic analysis of the biosynthetic arginine decarboxylase of Yersinia pestis utilizing arginine analogues as inhibitors and alternative substrates.
Topics: Amino Acid Sequence; Arginine; Canavanine; Carboxy-Lyases; Catalysis; Enzyme Inhibitors; Kinetics; Molecular Sequence Data; omega-N-Methylarginine; Recombinant Proteins; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Substrate Specificity; Yersinia pestis | 2003 |
L-arginine-dependent nitric oxide production of a murine macrophage-like RAW 264.7 cell line stimulated with Porphyromonas gingivalis lipopolysaccharide.
Topics: Analysis of Variance; Animals; Antibodies; Arginine; Cell Line; Enzyme Inhibitors; Interferon-gamma; Interleukin-10; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Porphyromonas gingivalis; Salmonella typhi; Time Factors | 2004 |
Impairment of fetal endothelium-dependent relaxation in a rat model of preeclampsia by chronic nitric oxide synthase inhibition.
Topics: Acetylcholine; Animals; Arginine; Dinoprost; Disease Models, Animal; Enzyme Inhibitors; Female; Fetus; Muscle Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroprusside; omega-N-Methylarginine; Potassium Chloride; Pre-Eclampsia; Pregnancy; Rats; Rats, Wistar; Vasodilation | 2004 |
Paraventricular nucleus activation of renal sympathetic neurones is synaptically depressed by nitric oxide and glycine acting at a spinal level.
Topics: Action Potentials; Animals; Arginine; Blood Pressure; Bronchodilator Agents; Drug Interactions; Enzyme Inhibitors; Glutamic Acid; Glycine; Glycine Agents; Homocysteine; Hydrazines; Injections, Spinal; Kidney; Male; Neurons; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; omega-N-Methylarginine; Paraventricular Hypothalamic Nucleus; Rats; Rats, Wistar; Spinal Cord; Strychnine; Sympathetic Nervous System; Synapses | 2004 |
Peripheral analgesic blockade of hypernociception: activation of arginine/NO/cGMP/protein kinase G/ATP-sensitive K+ channel pathway.
Topics: Adenosine Triphosphate; Analgesics; Animals; Arginine; Carbazoles; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dinoprostone; Indoles; Male; Nitric Oxide; Nociceptors; omega-N-Methylarginine; Oxadiazoles; Potassium Channels; Quinoxalines; Rats; Rats, Wistar; Signal Transduction | 2004 |
Prevention of doxorubicin-induced damage to rat heart myocytes by arginine analog nitric oxide synthase inhibitors and their enantiomers.
Topics: Animals; Animals, Newborn; Antibiotics, Antineoplastic; Arginine; Ascorbic Acid; Benzoquinones; Doxorubicin; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Free Radical Scavengers; L-Lactate Dehydrogenase; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Stereoisomerism | 2003 |
L-arginine transport in the human coronary and peripheral circulation.
Topics: Acetylcholine; Aged; Arginine; Biological Transport; Blood Vessels; Cardiac Catheterization; Coronary Vessels; Endothelium, Vascular; Female; Humans; Male; Middle Aged; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrogen Isotopes; omega-N-Methylarginine; Organ Specificity | 2004 |
Arginine and Leucine regulate p70 S6 kinase and 4E-BP1 in intestinal epithelial cells.
Topics: Androstadienes; Animals; Arginine; Carrier Proteins; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Immunoblotting; Intestines; Intracellular Signaling Peptides and Proteins; Leucine; Nitric Oxide Synthase; omega-N-Methylarginine; Ornithine; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Kinases; Rats; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Sirolimus; Time Factors; TOR Serine-Threonine Kinases; Wortmannin | 2004 |
Inactivated tumor suppressor Rb by nitric oxide promotes mitosis in human breast cancer cells.
Topics: Arginine; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Female; Humans; Mitosis; Nitric Oxide; omega-N-Methylarginine; Phosphorylation; Retinoblastoma Protein; Serine; Tumor Suppressor Protein p53 | 2004 |
Endothelium-dependent relaxation of canine pulmonary artery after prolonged lung graft preservation in University of Wisconsin solution: role of L-arginine supplementation.
Topics: Acetylcholine; Adenosine; Adenosine Diphosphate; Allopurinol; Animals; Arginine; Dogs; Endothelium, Vascular; Female; Glutathione; Insulin; Lung; Lung Transplantation; Male; Molsidomine; omega-N-Methylarginine; Organ Preservation Solutions; Pulmonary Artery; Raffinose; Sodium Fluoride; Tissue Preservation | 2004 |
NO stimulation of ATP-sensitive potassium channels: Involvement of Ras/mitogen-activated protein kinase pathway and contribution to neuroprotection.
Topics: Adenosine Triphosphate; Animals; Arginine; Humans; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Neurons; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Potassium Channels; ras Proteins; Rats | 2004 |
Roles of endogenous nitric oxide synthase inhibitors and endothelin-1 for regulating myometrial contractions during gestation in the rat.
Topics: Animals; Arginine; Cyclic GMP; Endothelin-1; Enzyme Inhibitors; Female; Isoenzymes; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Uterine Contraction | 2004 |
Involvement of increased arginase activity in impaired cavernous relaxation with aging in the rabbit.
Topics: Aging; Animals; Arginase; Arginine; Carbachol; Cholinergic Agonists; Endothelium, Vascular; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide Synthase; omega-N-Methylarginine; Penis; Rabbits | 2004 |
The effect of L-arginine on Porphyromonas gingivalis-induced phagocytosis of a murine macrophage-like RAW264.7 cell line.
Topics: Animals; Arginine; Cell Line; Macrophages; Mice; omega-N-Methylarginine; Phagocytosis; Porphyromonas gingivalis | 2004 |
Asymmetric dimethylarginine produces vascular lesions in endothelial nitric oxide synthase-deficient mice: involvement of renin-angiotensin system and oxidative stress.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Coronary Disease; Enzyme Induction; Homocysteine; Imidazoles; Infusion Pumps, Implantable; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microcirculation; Myocardium; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Olmesartan Medoxomil; omega-N-Methylarginine; Oxidative Stress; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Superoxides; Tetrazoles; Thiazepines | 2004 |
Increased response of renal perfusion to the antioxidant vitamin C in type 2 diabetes.
Topics: Aged; Antioxidants; Arginine; Ascorbic Acid; Case-Control Studies; Diabetes Mellitus, Type 2; Drug Combinations; Enzyme Inhibitors; Female; Humans; Hypertension; Infusions, Intravenous; Male; Middle Aged; omega-N-Methylarginine; Renal Circulation | 2004 |
Pathophysiology of unilateral ureteral obstruction: studies from Charlottesville to New York.
Topics: Animals; Arginine; Dogs; Enzyme Inhibitors; Genetic Therapy; Glomerular Filtration Rate; Kidney; Kidney Glomerulus; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Regional Blood Flow; Renin-Angiotensin System; Transforming Growth Factor beta; Ultrasonography; Ureter; Ureteral Obstruction; Vasoconstrictor Agents; Vasodilator Agents | 2004 |
Inhibition of l-arginine transport in platelets by asymmetric dimethylarginine and N-monomethyl-l-arginine: effects of arterial hypertension.
Topics: Adult; Arginine; Arteries; Biological Transport, Active; Blood Platelets; Enzyme Inhibitors; Female; Humans; Hypertension; Male; Middle Aged; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Oocytes; p-Chloromercuribenzoic Acid | 2004 |
Endogenous methylarginines modulate superoxide as well as nitric oxide generation from neuronal nitric-oxide synthase: differences in the effects of monomethyl- and dimethylarginines in the presence and absence of tetrahydrobiopterin.
Topics: Animals; Arginine; Biopterins; Calcium; Calmodulin; Cell Line; Citrulline; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Humans; Magnetics; Nitric Oxide Synthase; omega-N-Methylarginine; Oxygen; Rats; Spin Trapping; Superoxides; Time Factors; Transfection | 2005 |
eNOS, nNOS, cGMP and protein kinase G mediate the inhibitory effect of pancreastatin, a chromogranin A-derived peptide, on growth and proliferation of hepatoma cells.
Topics: Aminoquinolines; Animals; Arginine; Calcium; Carbazoles; Carcinoma, Hepatocellular; Cell Enlargement; Cell Proliferation; Chromogranin A; Chromogranins; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; DNA; Enzyme Inhibitors; Guanylate Cyclase; Indoles; Isoenzymes; Leucine; Liver; MAP Kinase Signaling System; Nerve Tissue Proteins; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Ornithine; Pancreatic Hormones; Peptides; Phospholipase C beta; Protein Isoforms; Rats; Receptors, Atrial Natriuretic Factor; Spermidine; Thymidine; Time Factors; Type C Phospholipases | 2005 |
Nitric oxide synthase inhibitors and nitric oxide donors modulate the biosynthesis of thaxtomin A, a nitrated phytotoxin produced by Streptomyces spp.
Topics: Arginine; Enzyme Inhibitors; Free Radical Scavengers; Guanidines; Indazoles; Indoles; Molecular Structure; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Piperazines; Streptomyces | 2005 |
Bradykinin down-regulates, whereas arginine analogs up-regulates, endothelial nitric-oxide synthase expression in coronary endothelial cells.
Topics: Arginine; Blotting, Western; Bradykinin; Cells, Cultured; Coronary Vessels; Down-Regulation; Endothelial Cells; Enzyme Inhibitors; Humans; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Up-Regulation | 2005 |
The role of NO in macrophage dysfunction at early stage after burn injury.
Topics: Animals; Arginine; Burns; Cell Division; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Lymphocytes; Macrophages; Mice; Mice, Inbred BALB C; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Prostaglandin-Endoperoxide Synthases; Spleen; Tumor Necrosis Factor-alpha | 2005 |
The transport of cationic amino acids in human airway cells: expression of system y+L activity and transepithelial delivery of NOS inhibitors.
Topics: Adenocarcinoma; Amino Acid Transport System y+L; Amino Acids; Animals; Arginine; Biological Transport; Cations; Cell Line; Cell Line, Tumor; Cell Membrane Permeability; Culture Media, Conditioned; Epithelial Cells; Gene Expression; Humans; Lung Neoplasms; Lysine; Macrophages; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; omega-N-Methylarginine; Respiratory System; Reverse Transcriptase Polymerase Chain Reaction | 2005 |
High-performance liquid chromatographic assay of N(G)-monomethyl-L-arginine, N(G),N(G)-dimethyl-L-arginine, and N(G),N(G)'-dimethyl-L-arginine using 4-fluoro-7-nitro-2, 1,3-benzoxadiazole as a fluorescent reagent.
Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Arginine; Chromatography, High Pressure Liquid; Drug Stability; Fluorescent Dyes; Male; omega-N-Methylarginine; Quality Control; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity | 2005 |
Retinal toxicity of commercial tissue plasminogen activator is mediated by the induction of nitric oxide in the mouse retinal primary cells.
Topics: Animals; Arginine; Bisbenzimidazole; Cell Culture Techniques; Cell Death; Commerce; Enzyme Inhibitors; Fibrinolytic Agents; Fluorescent Dyes; L-Lactate Dehydrogenase; Mice; Mice, Inbred ICR; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Retina; Time Factors; Tissue Plasminogen Activator | 2005 |
L-Arginine modulates CXC chemokines in the human intestinal epithelial cell line HCT-8 by the NO pathway.
Topics: Adenocarcinoma; Arginine; Cell Line, Tumor; Cell Survival; Chemokines, CXC; Humans; Intestinal Mucosa; Nitric Oxide; Nitric Oxide Donors; omega-N-Methylarginine; RNA, Messenger | 2005 |
Determination of methylated arginines by column-switching high-performance liquid chromatography-fluorescence detection.
Topics: Animals; Arginine; Calibration; Chromatography, High Pressure Liquid; Homoarginine; Male; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley | 2005 |
Elevations of plasma methylarginines in obesity and ageing are related to insulin sensitivity and rates of protein turnover.
Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Blood Glucose; Body Composition; Female; Glucose; Glucose Clamp Technique; Humans; Insulin; Insulin Resistance; Lipids; Male; Metabolic Syndrome; Middle Aged; Obesity; omega-N-Methylarginine; Proteins; Regression Analysis; Sex Characteristics | 2006 |
Biphasic effect of IL-1beta on the activity of argininosuccinate synthetase in Caco-2 cells. Involvement of nitric oxide production.
Topics: Arginine; Argininosuccinate Synthase; Caco-2 Cells; Humans; Interleukin-1beta; Nitric Oxide; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Protein Processing, Post-Translational | 2006 |
Low-frequency oscillations of the laser Doppler perfusion signal in human skin.
Topics: Acetylcholine; Adult; Arginine; Aspirin; Blood Flow Velocity; Enzyme Inhibitors; Fourier Analysis; Humans; Infusions, Intra-Arterial; Iontophoresis; Laser-Doppler Flowmetry; Male; Microcirculation; Nitroprusside; omega-N-Methylarginine; Regional Blood Flow; Skin; Vasodilator Agents | 2006 |
The antinociceptive activity of Muntingia calabura aqueous extract and the involvement of L-arginine/nitric oxide/cyclic guanosine monophosphate pathway in its observed activity in mice.
Topics: Acetic Acid; Analgesics; Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Elaeocarpaceae; Enzyme Inhibitors; Guanylate Cyclase; Male; Methylene Blue; Mice; Mice, Inbred BALB C; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Pain; Pain Measurement; Plant Extracts; Plant Leaves; Signal Transduction | 2006 |
Cyclo-oxygenase inhibition restores the attenuated vasodilation in manganese-deficient rat aorta.
Topics: Acetylcholine; Animals; Aorta; Arginine; Cyclooxygenase Inhibitors; Diet; Endothelium, Vascular; Enzyme Inhibitors; Male; Manganese; Muscle Contraction; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Phenylephrine; Rats; Rats, Sprague-Dawley; Vasodilation | 2006 |
Peripheral antinociceptive effect of pertussis toxin: activation of the arginine/NO/cGMP/PKG/ ATP-sensitive K channel pathway.
Topics: Adenosine Triphosphate; Analgesia; Analgesics; Animals; Arginine; Bucladesine; Carbazoles; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dinoprostone; Enzyme Inhibitors; Ganglia, Spinal; Glyburide; Indoles; KATP Channels; Male; Neurons; Nitric Oxide; omega-N-Methylarginine; Oxadiazoles; Pain; Pain Measurement; Pertussis Toxin; Potassium Channels, Inwardly Rectifying; Quinoxalines; Rats; Rats, Wistar; Signal Transduction; Tolbutamide | 2006 |
Evidence for the pathophysiological role of endogenous methylarginines in regulation of endothelial NO production and vascular function.
Topics: Animals; Aorta; Arginine; Carotid Artery Injuries; Catheterization; Cattle; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Humans; Kinetics; Male; Methylation; Nitric Oxide; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Rats; Rats, Wistar; Vasodilation | 2007 |
Effects of hydroxyurea and L-arginine on the production of nitric oxide metabolites in cultures of normal and sickle erythrocytes.
Topics: Adolescent; Adult; Anemia, Sickle Cell; Arginine; Cells, Cultured; Erythrocytes; Erythrocytes, Abnormal; Female; Hemoglobin A; Hemoglobin, Sickle; Humans; Hydrogen Peroxide; Hydroxyurea; Male; Middle Aged; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Oxidative Stress; Sampling Studies | 2006 |
Differential effects of nitric oxide synthase inhibitors on endothelium-dependent and nitrergic nerve-mediated vasodilatation in the bovine ciliary artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arginine; Bradykinin; Ciliary Arteries; Dogs; Electric Stimulation; Endothelium, Vascular; Enzyme Inhibitors; Myography; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Vasoconstrictor Agents; Vasodilation | 2007 |
Nitric oxide decreases ammonium release in tadpoles of the clawed frog, Xenopus laevis, Daudin.
Topics: Animals; Arginine; Cyclic GMP; Enzyme Inhibitors; Epidermis; Fluorescein; Gills; Handling, Psychological; Immunohistochemistry; Indicators and Reagents; Larva; Mitochondria; NADPH Dehydrogenase; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; omega-N-Methylarginine; Quaternary Ammonium Compounds; S-Nitroso-N-Acetylpenicillamine; Stress, Physiological; Xenopus laevis | 2007 |
Disruption of methylarginine metabolism impairs vascular homeostasis.
Topics: Acetylcholine; Amidohydrolases; Animals; Arginine; Blood Pressure; Blood Vessels; Blotting, Northern; Blotting, Western; Calcimycin; Cardiovascular Physiological Phenomena; Chromatography, High Pressure Liquid; Crystallography; Dose-Response Relationship, Drug; Echocardiography; Endothelium; Gene Deletion; Homeostasis; Humans; Mice; Models, Molecular; Muscle Contraction; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Phenylephrine; Rats; Rats, Sprague-Dawley; Signal Transduction; Vascular Resistance | 2007 |
Role of nitric oxide in the development of distant metastasis from squamous cell carcinoma.
Topics: Animals; Arginine; Carcinoma, Squamous Cell; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Shape; Disease Models, Animal; Endothelium-Dependent Relaxing Factors; Enzyme Inhibitors; Fluorescent Dyes; Head and Neck Neoplasms; Humans; Interleukin-1; Liver Circulation; Mice; Mice, Inbred BALB C; Mice, Nude; Microcirculation; Microscopy, Video; Muscle, Skeletal; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Nude | 2007 |
Differential signalling pathways involved in cholinoceptor-dependent stimulation of nitric oxide isoforms in dental pulp.
Topics: Animals; Arginine; Calmodulin; Dental Pulp; Enzyme Inhibitors; Guanidines; Male; Muscarinic Agonists; Neurotransmitter Agents; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Ornithine; Pilocarpine; Protein Kinase C; Rats; Rats, Wistar; Receptors, Muscarinic; Signal Transduction; Type C Phospholipases | 2007 |
Nitric oxide modulates ionic transport in the isolated intestine of the eel, Anguilla anguilla.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Anguilla; Animals; Arginine; Bicarbonates; Chlorides; Cyclic GMP; Diffusion Chambers, Culture; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Intestinal Absorption; Intestinal Mucosa; Intestines; Membrane Potentials; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Oxadiazoles; Permeability; Quinoxalines; Time Factors | 2007 |
Role of nitric oxide system in hydroxyl radical generation in rat striatum due to carbon monoxide poisoning, as determined by microdialysis.
Topics: Administration, Inhalation; Animals; Antimetabolites; Arginine; Carbon Monoxide; Carbon Monoxide Poisoning; Drug Interactions; Enzyme Inhibitors; Hydroxyl Radical; Inhalation Exposure; Male; Microdialysis; Neostriatum; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley | 2007 |
Developmental effects of perinatal exposure to extremely weak 7 Hz magnetic fields and nitric oxide modulation in the Wistar albino rat.
Topics: Animals; Animals, Newborn; Arginine; Body Weight; Defecation; Dose-Response Relationship, Radiation; Electromagnetic Fields; Enzyme Inhibitors; Female; Grooming; Motor Activity; Nervous System; Nitric Oxide; Nitric Oxide Synthase Type I; omega-N-Methylarginine; Pregnancy; Rats; Rats, Wistar; Sex Characteristics | 2007 |
[Effects of interleukin-1beta on nitric oxide production and ATP synthesis in rat surplus hepatocytes after partial hepatectomy].
Topics: Adenosine Triphosphate; Animals; Arginine; Cells, Cultured; Hepatectomy; Hepatocytes; Interleukin-1beta; Ketone Bodies; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats | 2007 |
Neuronal nitric oxide synthase regulates basal microvascular tone in humans in vivo.
Topics: Acetylcholine; Adult; Arginine; Brachial Artery; Citrulline; Forearm; Humans; Male; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Stress, Psychological; Thiourea; Vasodilation; Vasomotor System | 2008 |
Symmetric dimethylarginine is an independent predictor of intradialytic hypotension.
Topics: Aged; Arginine; Biomarkers; Blood Pressure; Female; Humans; Hypotension; Kidney Failure, Chronic; Male; Middle Aged; omega-N-Methylarginine; Predictive Value of Tests; Renal Dialysis | 2008 |
Regulation of eNOS-derived superoxide by endogenous methylarginines.
Topics: Arginine; Biopterins; Electron Spin Resonance Spectroscopy; Heme; Humans; NADP; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Superoxides | 2008 |
Nitric oxide modulates the frog heart ventricle morphodynamics.
Topics: Animals; Anura; Arginine; Cyclic GMP; Female; Heart Ventricles; In Vitro Techniques; Indazoles; Male; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Perfusion; Serine; Software; Ventricular Function | 2008 |
Impact of the endothelial nitric oxide synthase gene G894T polymorphism on renal endothelial function in patients with type 2 diabetes.
Topics: Alleles; Analysis of Variance; Arginine; Ascorbic Acid; Body Mass Index; Cholesterol, HDL; Diabetes Mellitus, Type 2; Endothelium; Female; Genotype; Guanine; Hemodynamics; Homozygote; Humans; Kidney; Male; Middle Aged; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Polymorphism, Single Nucleotide; Renal Plasma Flow; Thymine; Triglycerides | 2008 |
Determination of protein-incorporated methylated arginine reference values in healthy subjects whole blood and evaluation of factors affecting protein methylation.
Topics: Adult; Aged; Aged, 80 and over; Arginine; Female; Health; Humans; Male; Methylation; Middle Aged; omega-N-Methylarginine; Proteins; Reference Values; Regression Analysis | 2008 |
Mechanisms underlying erythrocyte and endothelial nitrite reduction to nitric oxide in hypoxia: role for xanthine oxidoreductase and endothelial nitric oxide synthase.
Topics: Allopurinol; Animals; Aorta; Arginine; Cell Hypoxia; Cells, Cultured; Endothelial Cells; Enzyme Inhibitors; Erythrocytes; Fluorometry; Humans; Hydrogen-Ion Concentration; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrite Reductases; Nitrites; omega-N-Methylarginine; Oxidation-Reduction; Rats; Rats, Wistar; Xanthine; Xanthine Dehydrogenase | 2008 |
Nitric oxide upregulates dimethylarginine dimethylaminohydrolase-2 via cyclic GMP induction in endothelial cells.
Topics: Amidohydrolases; Animals; Arginine; Carbazoles; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Male; Natriuretic Peptide, C-Type; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitro Compounds; omega-N-Methylarginine; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; RNA, Messenger; S-Nitroso-N-Acetylpenicillamine; Up-Regulation | 2008 |
Endogenous nitric oxide synthase inhibitors, arterial hemodynamics, and subclinical vascular disease: the PREVENCION Study.
Topics: Aged; Aged, 80 and over; Arginine; Biomarkers; Blood Flow Velocity; Blood Pressure; Carotid Artery Diseases; Female; Humans; Hypertension; Male; Middle Aged; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Predictive Value of Tests; Prognosis; Pulsatile Flow; Regression Analysis; Risk Factors | 2008 |
Investigating the biosynthetic origin of the nitro group in pyrrolomycins.
Topics: Actinomyces; Arginine; Atmosphere; Molecular Structure; Nitric Oxide Synthase; Nitrogen; Nitrogen Fixation; omega-N-Methylarginine; Pyrroles | 2008 |
Morphological and physiological study of the cardiac NOS/NO system in the Antarctic (Hb-/Mb-) icefish Chaenocephalus aceratus and in the red-blooded Trematomus bernacchii.
Topics: Animals; Antarctic Regions; Arginine; Blotting, Western; Cyclic GMP; Endocardium; Female; Fluorescent Antibody Technique; Heart Ventricles; Hemodynamics; Male; Molsidomine; Myocardium; NADPH Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Perciformes; Signal Transduction; Stroke Volume | 2009 |
ADMA injures the glomerular filtration barrier: role of nitric oxide and superoxide.
Topics: Albumins; Animals; Anthracenes; Arginine; Free Radical Scavengers; Glomerular Basement Membrane; Guanylate Cyclase; Male; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Oxidation-Reduction; Permeability; Propane; Rats; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Superoxides | 2009 |
Endogenous nitric oxide synthase inhibitors in sickle cell disease: abnormal levels and correlations with pulmonary hypertension, desaturation, haemolysis, organ dysfunction and death.
Topics: Anemia, Sickle Cell; Arginine; Case-Control Studies; Citrulline; Follow-Up Studies; Hemolysis; Humans; Hypertension, Pulmonary; Kidney Diseases; Linear Models; Nitric Oxide Synthase; omega-N-Methylarginine; Oxygen; Proportional Hazards Models; Risk; Survival Rate | 2009 |
Augmentation of platelet and endothelial cell eNOS activity decreases sepsis-related neutrophil-endothelial cell interactions.
Topics: Adult; Aged; Arginine; Endothelial Cells; Humans; Imines; Middle Aged; Neutrophils; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Platelet Activation; Platelet Aggregation; Shock, Septic | 2010 |
Targeted metabolomic evaluation of arginine methylation and cardiovascular risks: potential mechanisms beyond nitric oxide synthase inhibition.
Topics: Aged; Arginine; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Citrulline; Coronary Artery Disease; Creatinine; Female; Humans; Lysine; Male; Metabolomics; Methylation; Middle Aged; Nitric Oxide Synthase; Odds Ratio; omega-N-Methylarginine; Ornithine; Prognosis; Prospective Studies; Protein Processing, Post-Translational; Risk Assessment; Risk Factors; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Time Factors | 2009 |
Gonadal hormones decrease temporomandibular joint kappa-mediated antinociception through a down-regulation in the expression of kappa opioid receptors in the trigeminal ganglia.
Topics: Analgesics; Animals; Arginine; Cyclic GMP; Down-Regulation; Female; Gonadal Hormones; Humans; Male; Nitric Oxide; omega-N-Methylarginine; Oxadiazoles; Pain; Quinoxalines; Rats; Rats, Wistar; Receptors, Opioid, kappa; Sex Characteristics; Signal Transduction; Temporomandibular Joint; Trigeminal Ganglion | 2009 |
Analysis of arginine and methylated metabolites in human plasma by field amplified sample injection capillary electrophoresis tandem mass spectrometry.
Topics: Acetonitriles; Arginine; Electrophoresis, Capillary; Flow Injection Analysis; Humans; Linear Models; Methylation; omega-N-Methylarginine; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry | 2010 |
Differential sensitivity of basal and acetylcholine-induced activity of nitric oxide to blockade by asymmetric dimethylarginine in the rat aorta.
Topics: Acetylcholine; Animals; Aorta; Arginine; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Nitric Oxide; omega-N-Methylarginine; Phenylephrine; Rats; Rats, Wistar | 2010 |
L-arginine promotes DNA repair in cultured bronchial epithelial cells exposed to ozone: involvement of the ATM pathway.
Topics: Arginine; Ataxia Telangiectasia Mutated Proteins; Bronchi; Cell Cycle Proteins; Cell Line; Comet Assay; DNA Breaks, Double-Stranded; DNA Repair; DNA-Binding Proteins; Epithelial Cells; G1 Phase; Humans; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Ozone; Protein Serine-Threonine Kinases; Signal Transduction; Time Factors; Tumor Suppressor Proteins | 2011 |
Nitric oxide synthase inhibitors and cerebral vasospasm.
Topics: Animals; Arginine; Citrulline; Enzyme Inhibitors; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; S-Adenosylmethionine; Vasospasm, Intracranial | 2011 |
Bosentan and improved pulmonary endothelial function in pulmonary arterial hypertension.
Topics: Acetylcholine; Aged; Antihypertensive Agents; Arginine; Bosentan; Endothelium, Vascular; Familial Primary Pulmonary Hypertension; Female; Humans; Hypertension, Pulmonary; Lung; Male; Middle Aged; Nitroprusside; omega-N-Methylarginine; Pulmonary Artery; Sulfonamides; Ultrasonography | 2010 |
Arginase inhibition restores in vivo coronary microvascular function in type 2 diabetic rats.
Topics: Amino Acids; Animals; Arginase; Arginine; Blood Flow Velocity; Blood Glucose; Coronary Circulation; Diabetes Mellitus, Type 2; Disease Models, Animal; Enzyme Inhibitors; Insulin; Male; Microvessels; Nitrites; omega-N-Methylarginine; Rats; Rats, Wistar | 2011 |
Dimethylarginine dimethylaminohydrolase-1 is the critical enzyme for degrading the cardiovascular risk factor asymmetrical dimethylarginine.
Topics: Amidohydrolases; Animals; Arginine; Blood Pressure; Cardiovascular Diseases; Cells, Cultured; Endothelial Cells; Enzyme Inhibitors; Female; Genotype; Hypertension; Infusion Pumps, Implantable; Male; Mice; Mice, 129 Strain; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phenotype; Risk Factors; RNA Interference; Substrate Specificity; Time Factors; Transfection | 2011 |
A calcium-insensitive attenuated nitrosative stress response contributes significantly in the radioresistance of Sf9 insect cells.
Topics: Animals; Arginine; Calcium; Calcium Signaling; Calmodulin; Cell Line; Hemin; Humans; Insect Proteins; Lepidoptera; Membrane Potential, Mitochondrial; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Oxidative Stress; Radiation Tolerance; Reactive Nitrogen Species; Reactive Oxygen Species | 2011 |
DDAH says NO to ADMA.
Topics: Amidohydrolases; Animals; Arginine; Cardiovascular Diseases; Endothelial Cells; Humans; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Risk Factors; Substrate Specificity | 2011 |
Site-specific incorporation of arginine analogs into proteins using arginyl-tRNA synthetase.
Topics: Amino Acid Sequence; Aminoacylation; Arginine; Arginine-tRNA Ligase; Catalysis; Citrulline; Homoarginine; Methylation; Molecular Sequence Data; omega-N-Methylarginine; Protein Biosynthesis | 2011 |
Stimulus-specific blockade of nitric oxide-mediated dilatation by asymmetric dimethylarginine (ADMA) and monomethylarginine (L-NMMA) in rat aorta and carotid artery.
Topics: Animals; Aorta; Arginine; Carotid Arteries; Female; Male; Naphthyridines; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Phenylephrine; Pyrimidines; Rats; Rats, Wistar; Superoxide Dismutase; Vasodilation | 2011 |
Nitric oxide activity in platelets of dengue haemorrhagic fever patients: the apparent paradoxical role of ADMA and l-NMMA.
Topics: Adult; Arginine; Blood Platelets; Brazil; Enzyme Inhibitors; Female; Humans; Male; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Aggregation; Severe Dengue; Thrombocytopenia | 2012 |
Sex differences in renal responses to hyperglycemia, L-arginine, and L-NMMA in humans with uncomplicated type 1 diabetes.
Topics: Adult; Arginine; Blood Pressure; Diabetes Mellitus, Type 1; Female; Glomerular Filtration Rate; Hemodynamics; Humans; Hyperglycemia; Male; Nitric Oxide; omega-N-Methylarginine; Sex Characteristics; Young Adult | 2013 |
Heat-assisted extraction for the determination of methylarginines in serum by CE.
Topics: Arginine; Cardiovascular Diseases; Electrophoresis, Capillary; Hot Temperature; Humans; omega-N-Methylarginine; Solid Phase Extraction | 2013 |
L-arginine metabolism in early-onset and late-onset pre-eclamptic pregnancies.
Topics: Adult; Arginine; Biomarkers; Case-Control Studies; Female; Fetal Blood; Humans; omega-N-Methylarginine; Ornithine; Pre-Eclampsia; Pregnancy; Young Adult | 2013 |
Effects of medullary administration of a nitric oxide precursor on cardiovascular responses and neurotransmission during static exercise following ischemic stroke.
Topics: Animals; Arginine; Cardiovascular System; Female; gamma-Aminobutyric Acid; Glutamic Acid; Infarction, Middle Cerebral Artery; Microdialysis; Muscle Contraction; Muscle, Skeletal; Nitric Oxide; omega-N-Methylarginine; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley; Reperfusion; Stroke; Synaptic Transmission | 2013 |
Lactate is a possible mediator of the glucose effect on platelet inhibition.
Topics: Adult; Aged; Arginine; Aspirin; Blood Glucose; Blood Platelets; Dichloroacetic Acid; Female; Glucose; Glucose Transport Proteins, Facilitative; Humans; Lactic Acid; Male; Middle Aged; Nitroprusside; omega-N-Methylarginine; Platelet Aggregation; Platelet Aggregation Inhibitors; S-Nitrosoglutathione; Young Adult | 2014 |
Asymmetric dimethylarginine does not inhibit arginase activity and is pro-proliferative in pulmonary endothelial cells.
Topics: Animals; Arginase; Arginine; Cattle; Cell Proliferation; Endothelial Cells; Lung; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Substrate Specificity; Urea | 2014 |
Simultaneous determination of N(G)-monomethyl-L-arginine, N(G),N(G)-dimethyl-L-arginine, N(G),N(G')-dimethyl-L-arginine, and L-arginine using monolithic silica disk-packed spin columns and a monolithic silica column.
Topics: Arginine; Calibration; Chromatography, High Pressure Liquid; Fluorescent Dyes; Healthy Volunteers; Humans; Linear Models; omega-N-Methylarginine; Reproducibility of Results; Silicon Dioxide; Solid Phase Extraction | 2014 |
The ability of asymmetric dimethylarginine (ADMA) or monomethylarginine (L-NMMA) to block endothelium-dependent, nitric oxide-mediated relaxation in rat aorta is inversely related to the efficacy of the relaxant stimulus.
Topics: Animals; Aorta; Arginine; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Wistar; Vasodilation | 2014 |
Increased arginase levels contribute to impaired perfusion after cardiopulmonary resuscitation.
Topics: Adult; Arginase; Arginine; Capillaries; Cardiopulmonary Resuscitation; Enzyme Inhibitors; Female; Heart Arrest; Humans; Hypoxia; Male; Microcirculation; Nitric Oxide; omega-N-Methylarginine | 2014 |
Glucose uptake during contraction in isolated skeletal muscles from neuronal nitric oxide synthase μ knockout mice.
Topics: AMP-Activated Protein Kinases; Animals; Arginine; Biological Transport; Enzyme Inhibitors; Female; Glucose; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle Contraction; Muscle, Skeletal; Nitric Oxide; Nitric Oxide Synthase Type I; omega-N-Methylarginine; Physical Conditioning, Animal | 2015 |
Arginine methylation in yeast proteins during stationary-phase growth and heat shock.
Topics: Arginine; Gene Deletion; Heat-Shock Response; Hot Temperature; Mass Spectrometry; Methylation; omega-N-Methylarginine; Protein-Arginine N-Methyltransferases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2015 |
Myeloid-derived suppressor cells inhibit T cell proliferation in human extranodal NK/T cell lymphoma: a novel prognostic indicator.
Topics: Acetylcysteine; Adolescent; Adult; Aged; Arginine; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Proliferation; Cytokines; Enzyme Inhibitors; Female; Free Radical Scavengers; Gene Expression Regulation, Neoplastic; Humans; Lymphocyte Activation; Lymphoma, Extranodal NK-T-Cell; Male; Middle Aged; Myeloid Cells; Nitric Oxide; omega-N-Methylarginine; Reactive Oxygen Species; Young Adult | 2015 |
ADMA, subclinical changes and atrial fibrillation in the general population.
Topics: Adult; Aged; Arginine; Atrial Fibrillation; Biomarkers; Chromatography, Liquid; Echocardiography; Electrocardiography; Female; Germany; Humans; Male; Middle Aged; Morbidity; omega-N-Methylarginine; Oxidative Stress; Population Surveillance; Tandem Mass Spectrometry | 2016 |
Methylarginines in Mice with Experimental Atherosclerosis.
Topics: Animals; Arginine; Atherosclerosis; Cholesterol; Endothelium, Vascular; Male; Mice; Mice, Inbred CBA; Nitric Oxide Synthase; omega-N-Methylarginine; Poloxamer; Triglycerides | 2015 |
Whole-body synthesis of L-homoarginine in pigs and rats supplemented with L-arginine.
Topics: Animal Feed; Animals; Arginine; Body Weight; Creatinine; Dietary Supplements; Female; Glycine max; Homoarginine; Male; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Swine; Zea mays | 2016 |
Plasma concentrations of three methylated arginines, endogenous nitric oxide synthase inhibitors, in schizophrenic patients undergoing antipsychotic drug treatment.
Topics: Adult; Aged; Aged, 80 and over; Antipsychotic Agents; Arginine; Female; Humans; Male; Middle Aged; Nitric Oxide Synthase; omega-N-Methylarginine; Schizophrenia; Treatment Outcome; Young Adult | 2016 |
DdaR (PA1196) Regulates Expression of Dimethylarginine Dimethylaminohydrolase for the Metabolism of Methylarginines in Pseudomonas aeruginosa PAO1.
Topics: Amidohydrolases; Arginine; Bacterial Proteins; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; omega-N-Methylarginine; Pseudomonas aeruginosa; RNA Polymerase Sigma 54 | 2017 |
Inhibition of Rho kinase protects from ischaemia-reperfusion injury via regulation of arginase activity and nitric oxide synthase in type 1 diabetes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arginase; Arginine; Cytoprotection; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Drug Therapy, Combination; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide Synthase; omega-N-Methylarginine; Protein Kinase Inhibitors; Rats, Sprague-Dawley; rho GTP-Binding Proteins; rho-Associated Kinases; Signal Transduction | 2017 |
Plasma Arginine/Asymmetric Dimethylarginine Ratio and Incidence of Cardiovascular Events: A Case-Cohort Study.
Topics: Aged; Arginine; Cardiovascular Diseases; Case-Control Studies; Chromatography, Liquid; Citrulline; Cohort Studies; Female; Humans; Incidence; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; omega-N-Methylarginine; Ornithine; Proportional Hazards Models; Prospective Studies; Risk Factors; Stroke; Tandem Mass Spectrometry | 2017 |
The asymmetric dimethylarginine-mediated inhibition of nitric oxide in the rostral ventrolateral medulla contributes to regulation of blood pressure in hypertensive rats.
Topics: Amidohydrolases; Angiotensin II; Animals; Arginine; Blood Pressure; Heart Rate; Kidney; Losartan; Male; Medulla Oblongata; Nitric Oxide; omega-N-Methylarginine; Protein-Arginine N-Methyltransferases; Rats, Inbred WKY; Rats, Sprague-Dawley; Sympathetic Nervous System | 2017 |
Long-Term Intermittent Exposure to High Altitude Elevates Asymmetric Dimethylarginine in First Exposed Young Adults.
Topics: Acclimatization; Adolescent; Altitude; Altitude Sickness; Arginine; Chile; Humans; Hypoxia; Male; Military Personnel; Occupational Diseases; omega-N-Methylarginine; Young Adult | 2017 |
Metabolomic profiling of amines in sepsis predicts changes in NOS canonical pathways.
Topics: Adult; Aged; Amines; Animals; Arginine; Cell Line; Chromatography, Liquid; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Mass Spectrometry; Metabolomics; Mice; Middle Aged; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Sepsis | 2017 |
Symmetric dimethylarginine (SDMA) outperforms asymmetric dimethylarginine (ADMA) and other methylarginines as predictor of renal and cardiovascular outcome in non-dialysis chronic kidney disease.
Topics: Aged; Arginine; Biomarkers; Cardiovascular Diseases; Chromatography, Liquid; Disease Progression; Female; Germany; Humans; Incidence; Male; Middle Aged; omega-N-Methylarginine; Prognosis; Renal Dialysis; Renal Insufficiency, Chronic; Risk Assessment; Risk Factors | 2018 |
Changes in arginine are inversely associated with type 2 diabetes: A case-cohort study in the PREDIMED trial.
Topics: Aged; Aged, 80 and over; Arginine; Case-Control Studies; Citrulline; Cohort Studies; Diabetes Mellitus, Type 2; Diet, Fat-Restricted; Diet, Mediterranean; Female; Humans; Incidence; Insulin Resistance; Male; Middle Aged; omega-N-Methylarginine; Ornithine; Risk Factors | 2019 |
Total methylated arginine load as a risk parameter in subjects with masked hypertension.
Topics: Arginine; Biomarkers; Blood Pressure Determination; Female; Humans; Hypertension; Male; Masked Hypertension; Middle Aged; Nitric Oxide; omega-N-Methylarginine; Risk Factors | 2020 |
Negative Ion Mode Collision-Induced Dissociation for Analysis of Protein Arginine Methylation.
Topics: Amino Acid Sequence; Arginine; omega-N-Methylarginine; Peptides; Protein Processing, Post-Translational; Proteins; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2019 |
L-NAME releases nitric oxide and potentiates subsequent nitroglycerin-mediated vasodilation.
Topics: Animals; Arginine; Enzyme Inhibitors; Female; Mesenteric Arteries; Mice; Myography; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroglycerin; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; RAW 264.7 Cells; Reactive Oxygen Species; Sheep; Stereoisomerism; Vasodilation; Vasodilator Agents | 2019 |
The Role of Reactive Oxygen Species and Nitric Oxide in the Inhibition of
Topics: Arginine; Catecholamines; Cell Line; Enzyme Inhibitors; Humans; Imidazolines; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Peptide Hydrolases; Reactive Oxygen Species; Trichophyton | 2020 |
Methylarginine metabolites are associated with attenuated muscle protein synthesis in cancer-associated muscle wasting.
Topics: Animals; Arginine; Cachexia; Female; Heterografts; Humans; Male; Mice; Mice, Inbred C57BL; Mitochondria, Muscle; Muscle Proteins; Neoplasms; omega-N-Methylarginine | 2020 |
Altered methylarginine levels after surgery in subjects with multinodular goiter.
Topics: Adult; Arginine; Biomarkers; Case-Control Studies; Chromatography, High Pressure Liquid; Female; Goiter, Nodular; Humans; Male; Middle Aged; omega-N-Methylarginine; Postoperative Period; Sensitivity and Specificity | 2021 |
The Relationship of Methylated Arginines with Urine Cadmium Levels.
Topics: Arginine; Atherosclerosis; Cadmium; Creatinine; Humans; omega-N-Methylarginine | 2022 |
Evaluation of salivary and serum methylated arginine metabolites and nitric oxide synthase in advanced periodontitis patients.
Topics: Arginine; Humans; Inflammation; Interleukin-6; Nitric Oxide Synthase; omega-N-Methylarginine; Periodontal Diseases; Periodontitis; Tandem Mass Spectrometry | 2022 |
Effects of L-arginine on impaired blood fluidity after high-intensity exercise: An in vitro evaluation.
Topics: Arginine; Exercise; Humans; Leukocytes; Male; Nitric Oxide; omega-N-Methylarginine; Platelet Aggregation | 2022 |
Methylarginine efflux in nutrient-deprived yeast mitigates disruption of nitric oxide synthesis.
Topics: Arginine; Humans; Nitric Oxide; Nitric Oxide Synthase; Nutrients; omega-N-Methylarginine; Saccharomyces cerevisiae | 2023 |
Association of serum ADMA, SDMA and L-NMMA concentrations with disease progression in COVID-19 patients.
Topics: Arginine; COVID-19; Disease Progression; Humans; omega-N-Methylarginine | 2023 |
Effect of cigarette smoking on serum methylarginine and α-klotho levels.
Topics: Aging, Premature; Arginine; Cardiovascular Diseases; Cardiovascular System; Cigarette Smoking; Humans; omega-N-Methylarginine | 2023 |
Eight-Day Fast and a Single Bout of Exercise: The Effect on Serum Methylarginines and Amino Acids in Men.
Topics: Amino Acids; Arginine; Chromatography, Liquid; Humans; Male; omega-N-Methylarginine; Tandem Mass Spectrometry | 2023 |