arginine has been researched along with nitrites in 779 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 31 (3.98) | 18.7374 |
| 1990's | 348 (44.67) | 18.2507 |
| 2000's | 250 (32.09) | 29.6817 |
| 2010's | 136 (17.46) | 24.3611 |
| 2020's | 14 (1.80) | 2.80 |
| Authors | Studies |
|---|---|
| Bult, H; Herman, AG; Jorens, PG; Van Overveld, FJ; Vermeire, PA | 4 |
| Busse, R; Hauschildt, S; Mordvintcev, P; Mülsch, A; Vanin, A | 1 |
| Gross, SS; Levi, R | 1 |
| Moncada, S; Nava, E; Palmer, RM | 1 |
| Hishikawa, K; Kato, R; Nakaki, T; Saruta, T; Suzuki, H | 1 |
| Anggard, E; Mollace, V; Pistelli, A; Salvemini, D; Vane, J | 1 |
| Esumi, H; Hishikawa, K; Kato, R; Nakaki, T; Ohshima, H; Saruta, T; Suzuki, H; Tsuda, M | 1 |
| Hishikawa, K; Ikenaga, H; Kato, R; Nakaki, T; Saruta, T; Suzuki, H | 1 |
| Park, J; Rikihisa, Y | 1 |
| Eguchi, S; Emori, T; Hirata, Y; Imai, T; Kanno, K; Marumo, F; Ohta, K | 2 |
| Hacker, MP; Huot, AE; Kruszyna, H; Kruszyna, R; Smith, RP | 1 |
| Bassetti, S; Keist, R; Keller, R; Klauser, S; Mülsch, A | 1 |
| Farhood, A; Jaeschke, H; Schini, VB | 1 |
| Billiar, TR; Di Silvio, M; Geller, DA; Hoffman, RA; Madariaga, J; Nussler, AK; Selby, R; Simmons, RL | 1 |
| Courtois, Y; Goureau, O; Lepoivre, M | 1 |
| Arora, PK; Boje, KM | 1 |
| Corbett, JA; Hughes, JH; Lancaster, JR; McDaniel, ML; Sweetland, MA; Wang, JL; Wolf, BA | 1 |
| Flaman, JM; Henry, Y; Lepoivre, M | 1 |
| McGuigan, F; Sternberg, J | 1 |
| Assreuy, J; Moncada, S | 1 |
| Buster, BL; Miller, RD; Powell, LA; Ramirez, JA; Summersgill, JT | 1 |
| Aggarwal, BB; Awburn, MM; Clark, IA; Cowden, WB; Rockett, KA | 1 |
| Kalafut, F; Klobusická, M; Kusenda, J; Novotná, L | 1 |
| Bloom, BR; Chan, J; Magliozzo, RS; Xing, Y | 1 |
| Hartung, HP; Tausch, M; Toyka, KV; Zielasek, J | 1 |
| Baydoun, AR; Bogle, RG; Mann, GE; Moncada, S; Pearson, JD | 1 |
| Hoffman, RA; Langrehr, JM; Lee, TK; Müller, AR; Schraut, WH; Simmons, RL | 1 |
| Ryoyama, K | 1 |
| Junquero, DC; Schini, VB; Scott-Burden, T; Vanhoutte, PM | 1 |
| Hotchkiss, JH; Jacob, JR; Liu, RH; Tennant, BC | 1 |
| Arai, H; Igarashi, Y; Kodama, T | 1 |
| Corbett, JA; Lancaster, JR; McDaniel, ML; Sweetland, MA | 1 |
| Beasley, D; Brenner, BM; Schwartz, JH | 1 |
| Hattori, R; Kadota, K; Kawai, C; Uchizumi, H; Yui, Y | 1 |
| Hacker, MP; Huot, AE | 1 |
| Kwon, NS; Nathan, CF; Stuehr, DJ | 1 |
| Moncada, S; O'Connor, KJ | 1 |
| Fuchs, D; Hausen, A; Reibnegger, G; Wachter, H; Werner, ER; Werner-Felmayer, G | 1 |
| Klostergaard, J; Lopez-Berestein, G; Sivaramakrishnan, MR; Tucker, SD | 1 |
| Buchmüller-Rouiller, Y; Mauël, J; Ransijn, A | 1 |
| Corradin, SB; Mauël, J | 1 |
| Denis, M | 2 |
| Amber, IJ; Hibbs, JB; Johnson, BB; Parker, CJ; Taintor, RR; Vavrin, Z | 1 |
| Daulouède, S; Vincendeau, P | 1 |
| Befus, AD; Bissonnette, EY; Hogaboam, CM; Wallace, JL | 1 |
| Cook, HT; Sullivan, R | 1 |
| Bassenge, E; Bessler, W; Busse, R; Hauschildt, S; Mülsch, A | 1 |
| Ballermann, BJ; Marsden, PA | 1 |
| Drapier, JC; Gentilini, M; Mazier, D; Miltgen, F; Nüssler, A; Pied, S; Rénia, L | 1 |
| Gehri, R; Huf, E; Kayser, FH; Keist, R; Keller, R | 1 |
| Albina, JE; Henry, WL | 1 |
| Austic, RE; Dietert, RR; Hotchkiss, JH; Sung, YJ | 1 |
| Green, SJ; Hibbs, JB; Meltzer, MS; Nacy, CA | 1 |
| Belloni, P; Kilbourn, RG | 1 |
| Baeblich, S; Böhme, E; Schmidt, HH; Zernikow, B | 1 |
| Chenais, B; Lemaire, G; Lepoivre, M; Tenu, JP; Thelander, L; Yapo, A | 1 |
| Cameron, ML; Granger, DL; Koren, HS; Kozumbo, WJ; Weinberg, JB | 1 |
| Crawford, RM; Green, SJ; Hockmeyer, JT; Meltzer, MS; Nacy, CA | 1 |
| Li, Y; Liew, FY; Millott, S | 1 |
| Barbul, A; Kirk, SJ; Regan, MC | 1 |
| Billiar, TR; Curran, RD; Demetris, AJ; Harbrecht, BG; Simmons, RL; Stuehr, DJ | 1 |
| Aebischer, T; Balzer, M; De Libero, G; Erb, P; Groscurth, P; Keist, R; Keller, HU; Keller, R | 1 |
| Baeblich, SE; Böhme, E; Klein, MM; Schmidt, HH; Zernikow, BC | 1 |
| Geiges, M; Keist, R; Keller, R | 1 |
| Higashi, N; Higuchi, M; Osawa, T; Taki, H | 1 |
| Adams, LB; Hibbs, JB; Krahenbuhl, JL; Taintor, RR | 1 |
| Albina, JE; Caldwell, MD; Henry, WL; Mills, CD | 2 |
| Durack, DT; Granger, DL; Hibbs, JB; Perfect, JR | 1 |
| Kosaka, H; Leaf, CD; Miwa, M; Tannenbaum, SR; Wishnok, JS | 1 |
| Boudbid, H; Lepoivre, M; Petit, JF | 1 |
| Marletta, MA; Tayeh, MA | 1 |
| Billiar, TR; Curran, RD; Hofmann, K; Simmons, RL; West, MA | 1 |
| Glaven, J; James, SL | 1 |
| Billiar, TR; Curran, RD; Ferrari, FK; Simmons, RL; Stuehr, DJ | 1 |
| Gross, SS; Levi, R; Nathan, CF; Sakuma, I; Stuehr, DJ | 1 |
| Iyengar, R; Marletta, MA; Stuehr, DJ | 1 |
| Bentz, BG; Billiar, TR; Curran, RD; Simmons, RL; Stuehr, DJ; West, MA | 1 |
| Drapier, JC; Hibbs, JB; Wietzerbin, J | 1 |
| Iyengar, R; Leaf, CD; Marletta, MA; Wishnok, JS; Yoon, PS | 1 |
| Amber, IJ; Hibbs, JB; Taintor, RR; Vavrin, Z | 1 |
| Buttlaire, DH; Cohn, M | 2 |
| Nishikimi, M; Yagi, K | 1 |
| Radford, A | 1 |
| Purnell, DM | 1 |
| Greenblatt, M; Kommineni, VR; Lijinsky, W | 1 |
| Carbon, J; Curry, JB | 1 |
| Hamilton, PB; Sheeley, G | 1 |
| Greenblatt, M; Lijinsky, W | 1 |
| Mirvish, SS | 1 |
| Hariharasubramanian, V; Siegel, A | 1 |
| Ramsey, HH | 1 |
| Alkaitis, AA; Shafer, PR; Smith, RP | 1 |
| Ali, AM | 1 |
| Haas, D; Mercenier, A; Simon, JP; Stalon, V; Vander Wauven, C | 1 |
| Kassell, NF; Lee, KS; Suzuki, S | 1 |
| Giles, TD; Greenberg, SS; Grisham, MB; Lancaster, J; Powers, DR; Spitzer, JJ; Wang, JF; Xie, J | 1 |
| Acimovic, S; Andel, H; Függer, R; Längle, F; Mühlbacher, F; Roth, R; Steininger, R; Winkler, S | 1 |
| Colasanti, M; Lauro, GM; Mollace, V; Nistico, G; Rodino, P; Rotiroti, D | 1 |
| Adler, G; Beckh, K; Günthör, M; Lerch, MM; Weidenbach, H | 1 |
| Abebe, W; Hussain, T; Mustafa, SJ; Olanrewaju, H | 1 |
| Drapier, JC; Hirling, H; Kaldy, P; Kühn, LC; Wietzerbin, J | 1 |
| Beasley, D; McGuiggin, M | 1 |
| Allison, W; Chang, K; Corbett, JA; Hasan, K; Heesen, BJ; McDaniel, ML; Tilton, RG; Williamson, JR; Wolffenbuttel, BH | 1 |
| Courtois, Y; Goureau, O; Hicks, D | 1 |
| Gilkeson, GS; Granger, DL; Mason, SN; Misukonis, MA; Pippen, AM; Pisetsky, DS; Ruiz, P; Seldin, MF; Weinberg, JB; Wood, ER | 1 |
| Byam-Smith, M; Garfield, RE; Izumi, H; Yallampalli, C | 1 |
| Adler, H; Jungi, TW; Nicolet, J; Peterhans, E | 1 |
| Carpenter, A; Cohen, J; Evans, T; Silva, A | 1 |
| Adcock, IM; Buttery, LD; Kwon, OJ; Moncada, S; Polak, J; Riveros-Moreno, V; Robbins, RA; Springall, DR; Warren, JB; Wilson, AJ | 1 |
| Boeynaems, JM; Buurman, W; Preiser, JC; Vincent, JL; Wachel, D; Zhang, H | 1 |
| Berton, CC; Bogen, CM; Schott, CA; Stoclet, JC; Vetrovsky, P | 1 |
| Choi, DW; Corbett, JA; Hewett, SJ; McDaniel, ML | 1 |
| Smith, SD; Weiss, RM; Wheeler, MA | 1 |
| Currie, MG; Masferrer, JL; Misko, TP; Needleman, P; Salvemini, D; Seibert, K | 1 |
| Hevel, JM; Marletta, MA | 1 |
| Coffey, JW; Evans, CH; Hoffman, RA; Meschter, C; Meyers, K; Stefanovic-Racic, M | 1 |
| Inoue, M; Kida, T; Kobayashi, K; Kuroki, T | 1 |
| Currie, MG; Herman, LE; Wrenn, RW | 1 |
| Fischer, JE; Hasselgren, PO; Ogle, C; Rafferty, J; Tiao, G | 1 |
| Barnes, PJ; Buttery, LD; Geller, DA; Kwon, OJ; Polak, JM; Robbins, RA; Springall, DR; Warren, JB; Wilson, AJ | 1 |
| Colasanti, M; Lauro, GM; Mollace, V; Nistico, G; Rodino, P | 1 |
| Cunha, FQ; Silva, JS; Vespa, GN | 1 |
| Adashi, EY; Ben-Shlomo, I; Payne, DW | 1 |
| Shultz, PJ; Tolins, JP | 2 |
| Cattell, V; Cook, HT; Jansen, A; Largen, P; Lewis, S; O'Donnell, M; Reaveley, D | 1 |
| Adashi, EY; Ben-Shlomo, I; Jackson, MJ; Kokia, E; Payne, DW | 1 |
| Damais, C; Dugas, B; Kolb, JP; Paul-Eugène, N | 1 |
| Raij, L; Shultz, PJ; Tolins, JP; Westberg, G | 1 |
| Marletta, MA; Pufahl, RA; Wishnok, JS | 1 |
| Brahmbhatt, HP; Dawson, TM; Dawson, VL; Mong, JA | 1 |
| Henning, R; Klemm, P; Martorana, PA; Thiemermann, C; Winklmaier, G | 1 |
| Carter, G; Tracey, WR; Tse, J | 1 |
| Chen, LY; Kone, BC; Mehta, JL; Mehta, P; Turner, P | 1 |
| Caniggia, I; Chumley, P; Freeman, BA; Gutierrez, HH; Lowenstein, C; Pitt, BR; Schwarz, M; Watkins, SC | 1 |
| Bernatowicz, A; Fontana, A; Frei, K; Koedel, U; Paul, R; Pfister, HW | 1 |
| Mühl, H; Pfeilschifter, J | 1 |
| Godfrey, M; Grisham, MB; Majid, DS; Navar, LG | 1 |
| Didier, P; Greenberg, SS; Kolls, J; Mason, C; Xie, J | 1 |
| Arabolos, NS; Byrns, RE; Cederbaum, SD; Griscavage, JM; Ignarro, LJ; Jenkinson, CP; Kern, RM; Wang, WW | 1 |
| Bartoli, F; Billiar, TR; Di Silvio, M; Dorko, K; Freeswick, P; Geller, DA; Liu, ZZ; Nussler, AK | 1 |
| Bucher, B; Busse, R; Hecker, M; Schott, C; Stoclet, JC | 1 |
| Conte, A; Ottaviani, E | 1 |
| Dong, Z; Fidler, IJ; Gutman, M; Huang, S; Xie, K | 1 |
| Das, I; Sooranna, SR | 1 |
| Chang, SW; Ishizaki, T; Miyabo, S; Nakai, T; Ozawa, T; Shigemori, K; Voelkel, NF | 1 |
| Cahill, PA; Foster, C; Gingalewski, C; Redmond, EM; Sitzmann, JV; Wu, Y | 1 |
| Bauché, F; Guillemois, C; Jégou, B; Stéphan, JP | 1 |
| Kassell, NF; Sakai, N; Suzuki, S; Takenaka, K; Yamada, H | 1 |
| Bosia, A; Bussolino, F; Costamagna, C; Deharo, E; Gabrielli, G; Gautret, P; Ghigo, D; Ginsburg, H; Giribaldi, G; Pescarmona, G; Todde, R; Ulliers, D | 1 |
| al-Mehdi, AB; Fisher, AB; Ischiropoulos, H | 1 |
| Hey, C; Racké, K; Wessler, I | 1 |
| Cunningham, BD; Czuba, ZP; Król, W; Pietsz, G; Threadgill, MD | 1 |
| Lupini, M; Mannaioni, PF; Masini, E; Mugnai, L; Raspanti, S | 1 |
| Blum, M; Bogomolny, N; Chernichowsky, T; Finkelstein, A; Iaina, A; Koifman, B; Laniado, S; Peer, G; Scherez, J; Wollman, Y | 1 |
| Lipscomb, MF; Lovchik, JA; Lyons, CR | 1 |
| Hintze, TH; Nasjletti, A; Seyedi, N; Xu, X | 1 |
| Grimminger, F; Seeger, W; Spriestersbach, R; Walmrath, D; Weissmann, N | 1 |
| Criado-Jiménez, M; López-Novoa, JM; Martín-Oterino, JA; Rivas-Cabañero, L; Sánchez-Rodríguez, A | 1 |
| Akhtar, S; Buja, LM; Casscells, W; Golino, P; Ober, JC; Scott-Burden, T; Willerson, JT; Yao, SK | 1 |
| Bernatowicz, A; Fontana, A; Frei, K; Ködel, U; Pfister, HW | 1 |
| Ashab, I; Blum, M; Cabili, S; Chernihovsky, T; Hassner, A; Iaina, A; Peer, G; Schwartz, D; Silverberg, D; Wollman, Y | 1 |
| Komarov, AM; Lai, CS | 1 |
| Davis, S; Fischer, JE; Frederick, JA; Hasselgren, PO; Higashiguchi, T; Jacob, TD | 1 |
| Currie, MG; Kato, J; Misko, TP | 1 |
| Kolb, H; Kolb-Bachofen, V; Kröncke, KD; Rodriguez, ML | 1 |
| Corbett, JA; Currie, MG; Kasten, TP; McDaniel, ML; Misko, TP; Moore, WM; Nickols, GA; Tilton, RG; Williamson, JR | 1 |
| Damais, C; Frelin, C; Vigne, P | 1 |
| Gross, SS; Mitchell, JA; Szabó, C; Thiemermann, C; Vane, JR | 1 |
| Bagetta, G; Colasanti, M; Lauro, GM; Mollace, V; Nistico, G; Persichini, T | 1 |
| Byrns, RE; Fukuto, JM; Griscavage, JM; Ignarro, LJ; Rogers, NE | 1 |
| Kim, YM; Lancaster, JR | 1 |
| Turco, J; Winkler, HH | 1 |
| Frazzini, VI; Kader, A; Solomon, RA; Trifiletti, RR | 1 |
| Gustafsson, LE; Wiklund, CU; Wiklund, NP | 1 |
| Bijlsma, JA; Kaasjager, KA; Koomans, HA; Rabelink, AJ | 1 |
| Heuschling, P | 1 |
| Czarnecka, D; Dembinska-Kiec, A; Goldsztajn, P; Kawecka-Jaszcz, K; Malczewska-Malec, M; Siedlecki, A; Siemienska, T | 1 |
| Border, WA; Ketteler, M; Narita, I; Noble, NA; Ruoslahti, E | 1 |
| Distrutti, E; Fiorucci, S; Gulla, N; Morelli, A; Quintieri, A; Sarpi, L; Spirchez, Z | 1 |
| Olivares Fontt, E; Vray, B | 1 |
| Hori, M; Inoue, M; Kamada, T; Kitakaze, M; Komamura, K; Kosaka, H; Minamino, T; Node, K; Tada, M | 1 |
| Francis, PL; Leone, AM; Moncada, S; Rhodes PM [corrected to Rhodes, P]; Rhodes, P; Struthers, AD | 1 |
| Billiar, TR; Hoffman, RA; Langrehr, JM; Mueller, AR; Nalesnik, M; Nussler, AK; Platz, KP; Schraut, WH | 1 |
| Bryniarski, K; Marcinkiewicz, J; Ptak, W | 1 |
| Barnett, JB; Soderberg, LS | 1 |
| Diéguez, G; Fernández, N; García, JL; García-Villalón, AL; Gómez, B; Monge, L | 1 |
| Chang, KC; Chung, BH | 1 |
| Ando, M; Ando, Y; Gotoh, T; Sakashita, N; Tanaka, Y; Tashima, K; Uchino, M; Yamashita, T; Yonehara, T | 1 |
| Choi, BM; Chung, HT; Jl, KY; Jun, CD; Kim, HM; Kwak, HJ; Lee, BS; Lee, JY; Um, JY | 1 |
| Futterweit, S; Singhal, P; Trachtman, H | 1 |
| Damais, C; Dugas, B; Kolb, JP; Paul-Eugène, N; Yamaoka, K | 1 |
| Gómez-Jiménez, J; Martín, MC; Moncada, S; Mourelle, M; Peracaula, R; Salgado, A; Segura, RM | 1 |
| Candolfi, E; Hunter, CA; Remington, JS | 2 |
| Carnuccio, R; Di Rosa, M; Iuvone, T | 1 |
| Billiar, TR; Demetris, AJ; Di Silvio, M; Harbrecht, BG; Simmons, RL | 1 |
| Ferro, TJ; Johnson, A; Phelps, DT | 1 |
| Amaha, K; Emori, T; Hirata, Y; Ichikawa, K; Kanno, K; Mitaka, C; Yokoyama, K | 1 |
| Alexander, K; Bode-Böger, SM; Böger, RH; Creutzig, A; Frölich, JC; Gutzki, FM; Tsikas, D | 1 |
| Murata, K; Nakamura, T; Ono, Z; Sakamaki, T; Sato, K; Sawada, Y | 1 |
| Kassell, NF; Lee, KS; Suzuki, S; Takenaka, K | 1 |
| Campbell, C; Napolitano, LM | 1 |
| Bacon, EE; Blanchard, EJ; Kellum, JA; Kruckeberg, WC; Reckelhoff, JF; Wesley, AJ | 1 |
| Behboo, R; Korbanic, C; Lancaster, JR; Nussler, AK; Rao, AS; Ricordi, C | 1 |
| Damoulis, PD; Hauschka, PV | 1 |
| Dietz, KJ; Klughammer, B; Lang, B; Thume, M | 1 |
| Futami, Y; Maki, T; Sonaka, I | 1 |
| Bousquet, J; Chanez, P; Dugas, B; Kolb, JP; Mautino, G; Paul-Eugène, N; Vignola, AM | 1 |
| Blum, M; Cabili, S; Grosskopf, I; Iaina, A; Levo, Y; Maree, A; Peer, G; Schwartz, D; Serban, I; Wollman, Y | 1 |
| Li, HQ; Liu, R; Pan, J; Qin, SW; Shen, CK; Shi, Y; Wang, JH | 1 |
| Hayakawa, T; Kosaka, H; Kumura, E; Shiga, T; Yoshimine, T | 1 |
| Howard, DH; Lane, TE; Wu-Hsieh, BA | 1 |
| Huisman, E; Mulder, MF; Thijs, LG; van den Bos, GC; van Lambalgen, AA; Visser, JJ | 1 |
| Raij, L | 1 |
| Feng, HM; Walker, DH | 1 |
| Delaney, CA; Green, IC; Green, MH; Lowe, JE | 1 |
| Murphy, S; Simmons, ML | 1 |
| Cech, A; Daly, JM; Gallagher, H; Minnard, EA; Naama, H; Shou, J | 1 |
| Aynedjian, HS; Bank, N | 1 |
| Baydoun, AR; Bogle, RG; Mann, GE; Pearson, JD | 1 |
| Dull, KE; Hoffman, RA; Ildstad, ST; Langrehr, JM; McCarthy, SA; Simmons, RL; Wren, SM | 1 |
| Asensio, VC; Falanga, PB; Oshima, H | 1 |
| Stein, CS; Strejan, GH | 1 |
| Corbett, JA; Lancaster, JR; McDaniel, ML; Sweetland, MA; Wang, JL | 1 |
| Edwards, SW; Martin, JH | 1 |
| Akaike, T; Ando, M; Doi, T; Maeda, H; Sato, K; Suga, M | 1 |
| Hauschildt, S; Mordvintcev, PI; Mülsch, A; Vanin, AF | 1 |
| Byam-Smith, M; Garfield, RE; Yallampalli, C | 1 |
| Shibano, T; Vanhoutte, PM | 1 |
| Cox, GW; Melillo, G; Radzioch, D; Varesio, L | 1 |
| Baig, S; Bednar, I; Forsberg, G; Qureshi, GA; Siden, A; Södersten, P | 1 |
| Barton, CH; Blackwell, JM; Whitehead, SH | 1 |
| Guaza, C; Lledó, A; Molina-Holgado, F | 1 |
| Baylis, C; Charon, N; Hill, C; Losonczy, G; Qiu, C; Ruby, J; Samsell, L; Sütö, T; Venuto, R | 1 |
| Dubey, RK; Imthurn, B; Keller, PJ; Macas, E; Rosselli, M | 1 |
| Hentall, ID | 1 |
| Facchinetti, F; Galassi, MC; Mazza, V; Neri, I; Volpe, A | 1 |
| Gill, DJ; Grigor, MR; Low, BC | 1 |
| Duffy, C; Garthwaite, J; Salter, M; Strijbos, PJ | 1 |
| Fryburg, DA | 1 |
| Dong, YL; Yallampalli, C | 1 |
| Ikeda, U; Kanbe, T; Shimada, K | 1 |
| Campbell, A; Chesler, L; Geiser, AG; Letterio, JJ; Lucia, MS; Roberts, AB; Sporn, MB; Vodovotz, Y | 1 |
| O'Connor, M; Salzman, AL; Southan, GJ; Szabó, C; Zingarelli, B | 1 |
| Figliuzzi, M; Gaspari, F; Macconi, D; Noris, M; Paris, S; Remuzzi, G; Ruggenenti, P; Todeschini, M; Zoja, C | 1 |
| de Groot, R; Hoekman, K; Hop, WC; Huijmans, JG; Kornelisse, RF; Neijens, HJ; Sukhai, RN; van der Heijden, AJ; van der Straaten, PJ; Visser, JJ | 1 |
| Aihara, T; Ikeda, Y; Koyama, Y; Kusano, T; Muto, Y; Shiraishi, M | 1 |
| Monshouwer, M; Nujmeijer, SM; Van Amsterdam, JG; Van Miert, AS; Witkamp, RF | 1 |
| Cañada, FJ; Lamas, S; Pérez-Sala, D; Saura, M | 1 |
| Abe, K; Bannai, S; Fujiwara, K; Fujiwara, M; Sato, H; Shibazaki, T | 1 |
| Blum, M; Cabili, S; Csernihovsky, T; Iaina, A; Maree, A; Peer, G; Silverberg, DS; Wollman, Y | 1 |
| Cote, CG; Hassoun, PM; Liao, JK; Peng, HB; Yu, FS; Zulueta, JJ | 1 |
| Cattell, V; Cook, HT; Jansen, A; Reaveley, D; Waddington, S | 1 |
| Dennis, MF; Everett, SA; Patel, KB; Stratford, MR; Wardman, P | 1 |
| Han, SW; Kim, H | 1 |
| Fukuyama, N; Ichimori, K; Ishida, H; Nakazawa, H; Su, Z | 1 |
| Ceppi, ED; Smith, FS; Titheradge, MA | 1 |
| Bode-Boger, SM; Boger, RH; Frolich, JC; Gerecke, U; Gutzki, FM; Tsikas, D | 1 |
| Abeles, AJ; Block, ER; Patel, JM | 1 |
| López-Novoa, JM; Rivas-Cabañero, L; Valdivielso, JM | 1 |
| Maupoil, V; Paya, D; Rochette, L; Schott, C; Stoclet, JC | 1 |
| Hara, K; Komiyama, Y; Masuda, M; Murakami, T; Nambu, A; Nishimura, M; Takahashi, H; Yoshimura, M | 1 |
| Eisenstein, TK; Huang, D; Schwacha, MG | 1 |
| Andreesen, R; Konur, A; Krause, SW; Kreutz, M; Rehli, M | 1 |
| Chaturvedi, UC; Misra, A; Mukerjee, R | 1 |
| Cohen, J; Evans, TJ; Sriskandan, S | 1 |
| Kelly, RA; Simmons, WW; Smith, GK; Smith, TW; Ungureanu-Longrois, D | 1 |
| Facchinetti, F; Genazzani, AR; Neri, I | 1 |
| Ballèvre, L; Guignard, JP; Thonney, M | 1 |
| Jirillo, E; Mansi, G; Mitolo-Chieppa, D; Montagnani, M; Pece, S; Potenza, MA; Serio, M; Stoclet, JC | 1 |
| Ajami, AM; Beaumier, L; Castillo, L; Young, VR | 1 |
| Blum, M; Cabili, S; Chernihovsky, T; Goor, Y; Iaina, A; Peer, G; Silverberg, D; Wollman, Y | 1 |
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| Kayan-Tapan, T; Koçak, H; Öner-İyidoğan, Y; Seyithanoğlu, M; Tanrikulu-Küçük, S; Topparmak, E | 1 |
| Gambaryan, S; Tsikas, D | 1 |
| Balijepalli, AS; Comstock, AT; Hershenson, MB; Jensen, GC; Meyerhoff, ME; Sajjan, US; Wang, X; Zacharek, MA | 1 |
| Beckmann, B; Gold, R; Haghikia, A; Hanff, E; Kayacelebi, AA; Tsikas, D | 1 |
| Andre, T; McKinley-Barnard, S; Morita, M; Willoughby, DS | 1 |
| Frölich, JC; Huneau, JF; Langen, J; Lücke, T; Mariotti, F; Rothmann, S; Schneider, JY; Schröder, F; Tsikas, D | 1 |
| Chaturapanich, G; Lukkhananan, P; Sibmooh, N; Srihirun, S; Swaddiwudhipong, W; Thawonrachat, N; Unchern, S; Visoottiviseth, P; Vivithanaporn, P | 1 |
| Leung, SW; Vanhoutte, PM; Zhao, Y | 1 |
| Barchowsky, A; Bibby, KJ; Dheer, R; Dudash, M; Hazen, SL; Patterson, J; Shiva, S; Stachler, EN; Stolz, DB; Stolz, JF; Wang, Z | 1 |
| Abkhoo, A; Amiri, S; Boojar, MM; Dehpour, AR; Delazar, S; Hassanipour, M; Ostadhadi, S; Rahimi, N; Shirzadian, A | 1 |
| De Mia, M; Di Giacinto, N; Lemaire, SD; Maes, A; Marchand, CH; Morisse, S; Trost, P; Zaffagnini, M | 1 |
| Bhargava, K; Bhaumik, G; Gangwar, A; Himashree, G; Padhy, G; Sethy, NK; Sharma, M; Singh, K | 1 |
| Huang, FH; Hung, CY; Lee, CH; Lo, HC; Su, TC | 1 |
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| Azizi, F; Bahadoran, Z; Ghasemi, A; Mirmiran, P | 1 |
| Bárány, P; Békássy, Z; Cananau, C; Carlström, M; Checa, A; Hansson, S; Krmar, RT; Lundberg, JO; Sartz, L; Svensson, A; Weitzberg, E; Westphal, S; Wheelock, CE; Wide, K | 1 |
| Giam, B; Head, GA; Kaye, DM; Kuruppu, S; Rajapakse, NW | 1 |
| Boruc, O; Lambden, S; Lee, B; Leiper, J; Martin, D; Mythen, M; Piper, S; Tomlinson, J; Vanezis, K | 1 |
| Bailey, SJ; Blackwell, JR; Jones, AM; Vanhatalo, A; Williams, E; Winyard, PG; Wylie, LJ | 1 |
| Matsuura, C; Meirelles, CM | 1 |
| Elnazir, B; Greally, P; Kerley, CP; Kilbride, E | 1 |
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| Gertsen, M; Grasemann, C; Grasemann, H; Herrmann, R; Palmert, MR; Starschinova, J | 1 |
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| Fung, HL; Shin, S; Thapa, SK | 1 |
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| Garred, P; Hansen, MB; Hedegaard, ER; Hyldegaard, O; Madsen, MB; Perner, A; Pilely, K; Rasmussen, LS; Simonsen, U; Wahl, AM | 1 |
| Bedhomme, M; Collin, S; Conte, M; Corre, E; Dolch, LJ; Fourage, L; Jouhet, J; Laeuffer, F; Lupette, J; Magneschi, L; Maréchal, E; McGinn, P; Rébeillé, F; Reith, M; Richard, C; Richards, R; Seddiki, K; Tourcier, G | 1 |
| Hirayama, S; Iijima, K; Ishida, A; Miida, T; Morioka, I; Nagasaka, H; Nakacho, M; Takuwa, M; Tsukahara, H; Yorifuji, T; Yoshida, M | 1 |
| Dsilva, B; Joseph, A; Krishna, MB; Laloraya, M; Pillai, SM; Thomas, PL | 1 |
| Azevedo, AMM; Brites-Anselmi, G; Coeli-Lacchini, FB; de Almeida Belo, V; de Andrade, MF; Hirsch, E; Lacchini, R; Molina, CAF; Pinheiro, LC; Tanus-Santos, JE; Tucci, S | 1 |
| Li, A; Li, B; Liu, M; Wang, B; Wu, Q; Xiu, R; Zhang, H; Zhang, X | 1 |
| Bollenbach, A; Savvidou, MD; Tsikas, D | 1 |
| Kolpakov, IY; Kondrashova, VH; Kryzhanivska, VV; Leonovich, OS; Stepanova, YI; Vdovenko, VY; Zygalo, VM | 1 |
| Gao, Z; Li, H; Ma, L; Yang, Z; Zhang, P | 1 |
| Amini-Khoei, H; Amiri, S; Balali-Dehkordi, S; Dehpour, AR; Haj-Mirzaian, A; Hasanvand, A; Hassanipour, M; Kordjazy, N; Shirzadian, A | 1 |
| Buttice, S; Kisic, B; Kocic, G; Kocic, H; Miric, D; Nickovic, VP; Stojanovic, M | 1 |
| Chamanara, M; Dehpour, AR; Nikoui, V; Norouzi-Javidan, A; Ostadhadi, S; Shakiba, S; Zolfaghari, S | 1 |
| Bollenbach, A; Hanff, E; Tsikas, D | 1 |
| Fayh, APT; Krause, M; Rocha, IMGD; Rodrigues-Krause, J; Umpierre, D | 1 |
| Fernandes, GG; Frias, AT; Pinheiro, LC; Spiacci, A; Tanus-Santos, JE; Zangrossi, H | 1 |
| Abraham, A; Artaza, JN; Ferrini, MG; Flores, M; Graciano, L; Luna, R; Nguyen, S; Rajfer, J | 1 |
| Gómez, B; Rivera-Toledo, E; Santiago-Olivares, C | 1 |
| Béquet-Romero, M; Berlanga Acosta, J; Fabelo-Martínez, A; Fernández-Mayola, M; Figueroa-Martínez, A; García-Ojalvo, A; Guillén-Nieto, G; Mendoza-Marí, Y | 1 |
| Cao, Y; Feng, J; Guo, Y; Huang, C; Leng, J; Liu, Y; Tang, Y; Wang, Y; Yin, B; Zhao, Y | 1 |
| Matolinets, N | 1 |
| Desai, K; Martin, S | 1 |
| Feng, J; Geng, B; Huang, D; Tian, W; Zhang, Q; Zhu, S | 1 |
| Antoine, S; Cossenza, M; Domith, I; Duarte-Silva, AT; Gladulich, LFH; Hofmann, F; Khatri, L; Mejía-García, TA; Paes-de-Carvalho, R; Portugal, CC; Socodato, R; Ziff, EB | 1 |
| Bollenbach, A; Craig, A; Kruger, R; Mels, CMC; Schutte, AE; Schwedhelm, E; Tsikas, D | 1 |
| Amini-Khoei, H; Badi, AG; Omidi-Ardali, H; Saghaei, E | 1 |
| Chatterjee, D; Chrzanowska, M; Katafias, A; van Eldik, R | 1 |
| Djinović-Carugo, K; Furtmüller, PG; García-Rubio, I; Hofbauer, S; Mlynek, G; Obinger, C; Pfanzagl, V; Schmidt, D; Serra, I; Van Doorslaer, S | 1 |
| Aldubayan, M; Behera, RK; Behl, T; Bhatia, S; Bungau, S; Chauhan, M; Chigurupati, S; Farasani, A; Felemban, SG; Pal, G; Sharma, N; Singh, S | 1 |
| Beresewicz, A; Duda, M; Gajos-Draus, A | 1 |
| Beckmann, B; Brinkmann, F; Dillenhöfer, S; Frank, M; Hamelmann, E; Hanusch, B; Holtmann, M; Jöckel, KH; Koerner-Rettberg, C; Langrock, C; Legenbauer, T; Lücke, T; Maasjosthusmann, P; Reinehr, T; Sinningen, K; Tsikas, D | 1 |
| He, ZG; Hu, L; Zhang, H; Zhang, J | 1 |
| Beckmann, B; Blau, LS; Dimina, L; Finkel, A; Jantz, M; Lützow, M; Maassen, N; Mariotti, F; Röhrig, MA; Shushakov, V; Thorns, A; Tsikas, D | 1 |
| Araújo, NRA; Bezerra, GL; Lima, LKF; Lopes, LS; Pereira, SKS; Silva, SF; Silva-Néto, RP; Soares, AA | 1 |
| Beckmann, B; Böhme, P; Emons, B; Hanusch, B; Juckel, G; Lücke, T; Sinningen, K; Tsikas, D | 1 |
17 review(s) available for arginine and nitrites
| Article | Year |
|---|---|
On multiple forms of NO synthase and their occurrence in human cells.
Topics: Adjuvants, Immunologic; Amino Acid Oxidoreductases; Arginine; Calcium; Humans; Isoenzymes; Nitric Oxide Synthase; Nitrites; Nitrogen Oxides; Pteridines | 1991 |
[Measurement by in vivo brain dialysis of nitrite and nitrate levels as indices of nitric oxide production].
Topics: Animals; Arginine; Brain; Dialysis; Free Radicals; Kindling, Neurologic; Lipopolysaccharides; Neuroglia; Nitrates; Nitric Oxide; Nitrites; Pentylenetetrazole; Rats; Receptors, Glutamate; Signal Transduction | 2000 |
Nitric oxide synthase-independent generation of nitric oxide in muscle ischemia--reperfusion injury.
Topics: Animals; Arginine; Citrulline; Enzyme Inhibitors; Isoenzymes; Mice; Muscle, Skeletal; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Reperfusion Injury | 2000 |
Isotopic investigation of nitric oxide metabolism in disease.
Topics: Arginine; Biomarkers; Citrulline; Humans; Isotope Labeling; Nitrates; Nitric Oxide; Nitrites; Nitrogen Isotopes | 2003 |
Roles of nitric oxide and superoxide in inflammation.
Topics: 2-Naphthylamine; Animals; Arginine; Blotting, Western; Capillary Permeability; Chemotaxis, Leukocyte; Citrulline; Fluorescent Dyes; Fluorometry; Inflammation; Nitrates; Nitric Oxide; Nitrites; Oxidation-Reduction; Oxidative Stress; Peroxynitrous Acid; Rats; Superoxides; Tyrosine | 2003 |
The existence and significance of a mitochondrial nitrite reductase.
Topics: Animals; Antimycin A; Arginine; Cytosol; Electron Transport Complex IV; Endothelium-Dependent Relaxing Factors; Mitochondria; Models, Biological; Nitrite Reductases; Nitrites; Oxidants; Oxidation-Reduction; Oxidative Stress; Oxygen; Submitochondrial Particles | 2005 |
Analysis of nitrite and nitrate in biological fluids by assays based on the Griess reaction: appraisal of the Griess reaction in the L-arginine/nitric oxide area of research.
Topics: Animals; Arginine; Biological Assay; Body Fluids; Humans; Nitrates; Nitric Oxide; Nitrites | 2007 |
Recent methodological advances in the analysis of nitrite in the human circulation: nitrite as a biochemical parameter of the L-arginine/NO pathway.
Topics: Arginine; Clinical Laboratory Techniques; Humans; Luminescent Measurements; Nitric Oxide; Nitrites | 2007 |
Nitric oxide in plants: production and cross-talk with Ca2+ signaling.
Topics: Animals; Arabidopsis; Arginine; Calcium; Calcium-Transporting ATPases; Citrulline; Genome, Plant; Mammals; Nitrate Reductase; Nitric Oxide; Nitric Oxide Synthase; Nitriles; Nitrites; Plant Physiological Phenomena; Protein Kinases; Signal Transduction | 2008 |
Nitrate-nitrite-nitric oxide pathway: implications for anesthesiology and intensive care.
Topics: Administration, Inhalation; Anesthesia; Anesthesiology; Arginine; Cardiovascular Physiological Phenomena; Critical Care; Diet; Gastric Mucosa; Humans; Mitochondria; Nitrates; Nitric Oxide; Nitrites; Organ Transplantation; Oxygen Consumption; Saliva; Signal Transduction | 2010 |
Nitrite in pulmonary arterial hypertension: therapeutic avenues in the setting of dysregulated arginine/nitric oxide synthase signalling.
Topics: Arginine; Familial Primary Pulmonary Hypertension; Humans; Hypertension, Pulmonary; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Signal Transduction | 2011 |
The biochemistry of asthma.
Topics: Aldehyde Oxidoreductases; Animals; Arginase; Arginine; Asthma; Humans; Hydrogen-Ion Concentration; Nitrites | 2011 |
A review and discussion of platelet nitric oxide and nitric oxide synthase: do blood platelets produce nitric oxide from L-arginine or nitrite?
Topics: Animals; Arginine; Blood Platelets; Humans; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitrites | 2015 |
Vascular nitric oxide: Beyond eNOS.
Topics: Animals; Arginine; Cardiovascular Diseases; Cell Physiological Phenomena; Cyclic GMP; Endothelium, Vascular; Guanylate Cyclase; Humans; Muscle Contraction; Muscle Tonus; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; S-Nitrosothiols; Signal Transduction | 2015 |
Protein S-nitrosylation in photosynthetic organisms: A comprehensive overview with future perspectives.
Topics: Arginine; Nitric Oxide; Nitrites; Plant Proteins; Plants; Protein Processing, Post-Translational; Proteomics | 2016 |
Association of l-Arginine Supplementation with Markers of Endothelial Function in Patients with Cardiovascular or Metabolic Disorders: A Systematic Review and Meta-Analysis.
Topics: Adult; Aged; Arginine; Cardiovascular Diseases; Diabetes Mellitus; Dietary Supplements; Endothelium, Vascular; Female; Humans; Hyperemia; Male; Middle Aged; Nitrates; Nitrites; Obesity; Treatment Outcome | 2018 |
Reaction mechanisms relevant to the formation and utilization of [Ru(edta)(NO)] complexes in aqueous media.
Topics: Arginine; Azides; Catalysis; Coordination Complexes; Free Radical Scavengers; Iron; Nitric Oxide; Nitrites; Oxidation-Reduction; Ruthenium; S-Nitrosothiols | 2021 |
49 trial(s) available for arginine and nitrites
| Article | Year |
|---|---|
Improvement of cardiac performance by intravenous infusion of L-arginine in patients with moderate congestive heart failure.
Topics: Aged; Arginine; Coronary Disease; Female; Heart Failure; Hemodynamics; Humans; Injections, Intravenous; Male; Middle Aged; Nitrates; Nitrites | 1995 |
L-arginine/nitric oxide pathway modulates gastric motility and gallbladder emptying induced by erythromycin and liquid meal in humans.
Topics: Adult; Analysis of Variance; Arginine; Double-Blind Method; Drug Interactions; Erythromycin; Fasting; Feeding Behavior; Female; Gallbladder Emptying; Gastrointestinal Motility; Humans; Male; Nitric Oxide; Nitrites | 1995 |
L-arginine infusion decreases peripheral arterial resistance and inhibits platelet aggregation in healthy subjects.
Topics: Adult; Arginine; Cyclic GMP; Double-Blind Method; Gas Chromatography-Mass Spectrometry; Heart Rate; Humans; Male; Nitrates; Nitrites; Platelet Aggregation; Platelet Aggregation Inhibitors; Vascular Resistance | 1994 |
Effects of L-arginine on utero-placental circulation in growth-retarded fetuses.
Topics: Adult; Arginine; Blood Flow Velocity; Female; Fetal Growth Retardation; Humans; Infusions, Parenteral; Maternal Age; Neurotransmitter Agents; Nitric Acid; Nitric Oxide; Nitrites; Parity; Placental Circulation; Pregnancy | 1996 |
The role of nitric oxide in bacterial meningitis in children.
Topics: Adolescent; Anti-Inflammatory Agents; Arginine; Blood-Brain Barrier; Case-Control Studies; Child; Child, Preschool; Dexamethasone; Female; Humans; Infant; Male; Meningitis, Bacterial; Nitrates; Nitric Oxide; Nitrites; Tumor Necrosis Factor-alpha | 1996 |
L-arginine infusion decreases platelet aggregation through an intraplatelet nitric oxide release.
Topics: Adenosine Diphosphate; Adult; Arginine; Blood Pressure; Citrulline; Collagen; Diastole; Female; Humans; Infusions, Intravenous; Nitric Oxide; Nitrites; Placebos; Platelet Aggregation; Systole; Time Factors | 1997 |
Angiotensin-converting enzyme inhibition, but not calcium antagonism, improves a response of the renal vasculature to L-arginine in patients with essential hypertension.
Topics: Adult; Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Arginine; Calcium Channel Blockers; Data Interpretation, Statistical; Double-Blind Method; Endothelium, Vascular; Female; Humans; Hypertension; Imidazoles; Imidazolidines; Infusions, Intravenous; Kidney; Male; Middle Aged; Nitrates; Nitric Oxide; Nitrites; Renal Circulation; Time Factors; Vascular Resistance | 1998 |
Serum nitrite sensitively reflects endothelial NO formation in human forearm vasculature: evidence for biochemical assessment of the endothelial L-arginine-NO pathway.
Topics: Acetylcholine; Adult; Analysis of Variance; Arginine; Arteriosclerosis; Biomarkers; Endothelium, Vascular; Female; Forearm; Humans; Male; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Papaverine; Regional Blood Flow; Regression Analysis; Vasodilator Agents | 1999 |
Transient improvement of acetylcholine responses after short-term oral L-arginine in forearms of human heart failure.
Topics: Acetylcholine; Administration, Oral; Adult; Analysis of Variance; Arginine; Blood Pressure; Cross-Over Studies; Double-Blind Method; Female; Forearm; Heart Failure; Humans; Ischemia; Male; Middle Aged; Nitrates; Nitrites; Nitroprusside; Norepinephrine; Vasoconstrictor Agents; Vasodilator Agents | 2000 |
Early alteration in glomerular reserve in humans at genetic risk of essential hypertension: mechanisms and consequences.
Topics: Adult; Amino Acids; Arginine; Cyclic GMP; Female; Genetic Markers; Glomerular Filtration Rate; Humans; Hypertension; Infusions, Intravenous; Insulin; Insulin Resistance; Kidney Glomerulus; Kidney Tubules, Proximal; Lithium Carbonate; Male; Middle Aged; Nitrates; Nitrites; Phenotype; Risk Factors; Second Messenger Systems | 2001 |
Adjuvant L-arginine treatment in controlled ovarian hyperstimulation: a double-blind, randomized study.
Topics: Adjuvants, Pharmaceutic; Administration, Oral; Adult; Arginine; Chorionic Gonadotropin, beta Subunit, Human; Double-Blind Method; Drug Therapy, Combination; Embryo Transfer; Embryo, Mammalian; Female; Fertilization in Vitro; Follicle Stimulating Hormone; Follicular Fluid; Gonadotropin-Releasing Hormone; Humans; Nitrates; Nitrites; Ovarian Follicle; Ovulation Induction; Pregnancy; Pregnancy Rate; Prospective Studies; Reference Values | 2002 |
Paradoxical decrease in plasma NOx by L-arginine load in diabetic and non-diabetic subjects.
Topics: Arginine; Blood Glucose; Blood Pressure; Cyclic GMP; Diabetes Mellitus, Type 2; Endothelium, Vascular; Female; Humans; Hypertension; Male; Middle Aged; Nitrates; Nitric Oxide; Nitrites | 2002 |
L-arginine infusion decreases plasma total homocysteine concentrations through increased nitric oxide production and decreased oxidative status in Type II diabetic patients.
Topics: Arginine; Blood Pressure; Cross-Over Studies; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Homocysteine; Humans; Infusions, Intravenous; Male; Middle Aged; Nitrates; Nitric Oxide; Nitrites; Osmolar Concentration; Oxidative Stress; Reference Values; Sulfhydryl Compounds | 2002 |
Relationship between salt intake, nitric oxide and asymmetric dimethylarginine and its relevance to patients with end-stage renal disease.
Topics: Arginine; Blood Pressure; Cardiovascular Diseases; Female; Humans; Hypertension; Kidney Failure, Chronic; Male; Middle Aged; Nitrates; Nitric Oxide; Nitrites; Renal Dialysis; Risk Factors; Sodium Chloride | 2002 |
Effects of simvastatin and L-arginine on vasodilation, nitric oxide metabolites and endogenous NOS inhibitors in hypercholesterolemic subjects.
Topics: Anticholesteremic Agents; Arginine; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Free Radicals; Humans; Hypercholesterolemia; Lipids; Male; Middle Aged; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; S-Nitrosothiols; Simvastatin; Time Factors; Vasodilation | 2003 |
Sulfhydryl angiotensin-converting enzyme inhibition induces sustained reduction of systemic oxidative stress and improves the nitric oxide pathway in patients with essential hypertension.
Topics: Angiotensin-Converting Enzyme Inhibitors; Arginine; Captopril; Enalapril; Female; Humans; Hypertension; Lipid Peroxidation; Lipoproteins, LDL; Male; Middle Aged; Nitrates; Nitric Oxide; Nitrites; Oxidative Stress | 2004 |
Elevated plasma concentration of asymmetric dimethylarginine that is reduced by single dose testosterone administration in idiopathic hypogonadotropic hypogonadism patients.
Topics: Adult; Androgens; Arginine; Humans; Hypogonadism; Male; Nitrates; Nitric Oxide; Nitrites; Testosterone | 2005 |
Amelioration of vascular endothelial dysfunction in obstructive sleep apnea syndrome by nasal continuous positive airway pressure--possible involvement of nitric oxide and asymmetric NG, NG-dimethylarginine.
Topics: Adult; Aged; Arginine; Brachial Artery; Continuous Positive Airway Pressure; Endothelium, Vascular; Humans; Male; Middle Aged; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Sleep Apnea, Obstructive; Vasodilation | 2005 |
Home-based exercise training modulates pro-oxidant substrates in patients with chronic heart failure.
Topics: Adult; Arginine; Cross-Over Studies; Exercise; Female; Heart Failure; Humans; Hypoxanthine; Male; Middle Aged; Nitrates; Nitrites; Xanthine | 2005 |
Plasma markers of NO synthase activity in women after ovarian hyperstimulation: influence of estradiol on ADMA.
Topics: Adult; Arginine; Cells, Cultured; Endothelial Cells; Estradiol; Female; Follicle Stimulating Hormone; Follicular Phase; Humans; Luteinizing Hormone; Nitrates; Nitric Oxide Synthase; Nitrites; Ovulation Induction; Recombinant Proteins | 2006 |
Daily consumption for six weeks of a lignan complex isolated from flaxseed does not affect endothelial function in healthy postmenopausal women.
Topics: 4-Butyrolactone; Aged; Arginine; Blood Pressure; Body Weight; Cross-Over Studies; Diet; Double-Blind Method; Endothelin-1; Endothelium, Vascular; Female; Flax; Humans; Lignans; Middle Aged; Nitrates; Nitrites; Nitroglycerin; Patient Compliance; Placebos; Postmenopause; Vasodilation | 2006 |
Effects of normalization of plasma testosterone levels in hypogonadal men on plasma levels and urinary excretion of asymmetric dimethylarginine (ADMA).
Topics: Adult; Aged; Arginine; Body Mass Index; Humans; Hypogonadism; Male; Middle Aged; Nitrates; Nitrites; Testosterone | 2008 |
Enhanced concentrations of relevant markers of nitric oxide formation after exercise training in patients with metabolic syndrome.
Topics: Adult; Arginine; Biomarkers; Cyclic GMP; Exercise Therapy; Humans; Lipid Peroxides; Metabolic Syndrome; Middle Aged; Nitric Oxide; Nitrites; Oxidative Stress; Thiobarbituric Acid Reactive Substances | 2008 |
Effects of L-citrulline oral supplementation on polymorphonuclear neutrophils oxidative burst and nitric oxide production after exercise.
Topics: Administration, Oral; Arginine; Bicycling; Citrulline; Creatine Kinase; Dietary Supplements; DNA Damage; Double-Blind Method; Exercise; Humans; L-Lactate Dehydrogenase; Malates; Male; Malondialdehyde; Neutrophil Activation; Neutrophils; Nitric Oxide; Nitrites; Respiratory Burst; Time Factors; Young Adult | 2009 |
Effects of an exercise intervention using Dance Dance Revolution on endothelial function and other risk factors in overweight children.
Topics: Arginine; Biomarkers; Blood Glucose; Blood Pressure; Body Height; Body Mass Index; Body Weight; Brachial Artery; Child; Dance Therapy; Endothelium, Vascular; Exercise Therapy; Female; Humans; Inflammation Mediators; Insulin; Lipids; Male; Nitrates; Nitrites; Overweight; Oxygen Consumption; Patient Compliance; Physical Fitness; Risk Factors; Time Factors; Treatment Outcome; Ultrasonography; Vasodilation; Video Games | 2009 |
L-arginine supplemented nondiluted blood cardioplegia: a clinical trial.
Topics: Aged; Arginine; Biomarkers; Cardioplegic Solutions; Chi-Square Distribution; Coronary Artery Bypass; Dose-Response Relationship, Drug; Female; Heart Arrest, Induced; Heart Diseases; Humans; Lactic Acid; Male; Middle Aged; Nitrates; Nitrites; Time Factors; Treatment Outcome | 2010 |
L-citrulline-malate influence over branched chain amino acid utilization during exercise.
Topics: Administration, Oral; Amino Acids, Branched-Chain; Arginine; Bicycling; Biomarkers; Citrulline; Creatinine; Dietary Proteins; Dietary Supplements; Double-Blind Method; Exercise; Human Growth Hormone; Humans; Insulin; Malates; Male; Muscle, Skeletal; Nitrites; Ornithine; Time Factors; Urea; Young Adult | 2010 |
Acute L-arginine supplementation reduces the O2 cost of moderate-intensity exercise and enhances high-intensity exercise tolerance.
Topics: Administration, Oral; Adult; Arginine; Beverages; Blood Pressure; Cross-Over Studies; Dietary Supplements; Double-Blind Method; England; Exercise; Exercise Tolerance; Humans; Male; Muscle Contraction; Muscle, Skeletal; Nitric Oxide; Nitrites; Oxygen Consumption; Pulmonary Gas Exchange; Time Factors; Young Adult | 2010 |
Effect of oral arginine supplementation on exhaled nitric oxide concentration in sickle cell anemia and acute chest syndrome.
Topics: Acute Chest Syndrome; Acute Disease; Administration, Oral; Adolescent; Anemia, Sickle Cell; Arginine; Aspartic Acid; Breath Tests; Child; Citrulline; Female; Glutamic Acid; Humans; Male; Nitrates; Nitric Oxide; Nitrites; Ornithine; Young Adult | 2010 |
No arguments for increased endothelial nitric oxide synthase activity in migraine based on peripheral biomarkers.
Topics: Area Under Curve; Arginine; Biomarkers; Citrulline; Cyclic GMP; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites | 2010 |
Bolus arginine supplementation affects neither muscle blood flow nor muscle protein synthesis in young men at rest or after resistance exercise.
Topics: Arginine; Dietary Supplements; Endothelin-1; Exercise; Femoral Artery; Human Growth Hormone; Humans; Male; Muscle Proteins; Muscle, Skeletal; Myofibrils; Nitrates; Nitric Oxide; Nitrites; Protein Biosynthesis; Regional Blood Flow; Resistance Training; Rest; Young Adult | 2011 |
Influence of dietary fat ingestion on asymmetrical dimethylarginine in lean and obese human subjects.
Topics: Adult; Arginine; Chromatography, Gas; Cross-Over Studies; Diet; Dietary Fats; Eating; Energy Intake; Female; Humans; Male; Meals; Nitrates; Nitrites; Obesity; Tandem Mass Spectrometry | 2012 |
The acute effects of a low and high dose of oral L-arginine supplementation in young active males at rest.
Topics: Administration, Oral; Adult; Arginine; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Growth Hormone; Humans; Insulin-Like Growth Factor I; Male; Nitrates; Nitrites; Rest; Young Adult | 2011 |
The impact of pioglitazone on ADMA and oxidative stress markers in patients with type 2 diabetes.
Topics: Academic Medical Centers; Arginine; Biomarkers; Cross-Over Studies; Diabetes Mellitus, Type 2; Dinoprost; F2-Isoprostanes; Female; Humans; Hypoglycemic Agents; Male; Middle Aged; Nitrates; Nitrites; Oxidative Stress; Pioglitazone; Prospective Studies; South Carolina; Thiazolidinediones; Time Factors; Treatment Outcome | 2012 |
Effects of 7 days of arginine-alpha-ketoglutarate supplementation on blood flow, plasma L-arginine, nitric oxide metabolites, and asymmetric dimethyl arginine after resistance exercise.
Topics: Adolescent; Adult; Arginine; Blood Pressure; Dietary Supplements; Double-Blind Method; Heart Rate; Hemodynamics; Humans; Ketoglutaric Acids; Male; Nitrates; Nitric Oxide; Nitrites; Resistance Training; Young Adult | 2011 |
Acute l-arginine supplementation increases muscle blood volume but not strength performance.
Topics: Adult; Analysis of Variance; Arginine; Biomarkers; Biomechanical Phenomena; Blood Volume; Brazil; Dietary Supplements; Double-Blind Method; Humans; Male; Muscle Contraction; Muscle Strength; Muscle, Skeletal; Nitrates; Nitric Oxide; Nitrites; Oxygen Consumption; Recovery of Function; Regional Blood Flow; Resistance Training; Spectroscopy, Near-Infrared; Time Factors; Torque; Upper Extremity; Vasodilation; Young Adult | 2012 |
Vascular effects of nebivolol added to hydrochlorothiazide in African Americans with hypertension and echocardiographic evidence of diastolic dysfunction: the NASAA study.
Topics: Adult; Aged; Antihypertensive Agents; Arginine; Benzopyrans; Black or African American; Dose-Response Relationship, Drug; Drug Therapy, Combination; Echocardiography; Ethanolamines; Female; Heart Failure, Diastolic; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nebivolol; Nitrates; Nitric Oxide; Nitrites | 2012 |
No effect of acute L-arginine supplementation on O₂ cost or exercise tolerance.
Topics: Adult; Arginine; Carbohydrates; Dietary Supplements; Double-Blind Method; Exercise Tolerance; Humans; Male; Nitrites; Oxygen Consumption; Running | 2013 |
Hypothermia decreases cerebrospinal fluid asymmetric dimethylarginine levels in children with traumatic brain injury.
Topics: Adolescent; Arginine; Brain Injuries; Case-Control Studies; Cerebrospinal Fluid; Child; Child, Preschool; Chromatography, Liquid; Female; Humans; Hypothermia, Induced; Infant; Male; Nitrates; Nitrites; Tandem Mass Spectrometry | 2013 |
Altered nitric oxide bioavailability contributes to diesel exhaust inhalation-induced cardiovascular dysfunction in man.
Topics: Adult; Air Pollutants; Arginine; Biological Availability; Blood Pressure; Cardiac Output; Cardiovascular Diseases; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Enzyme Inhibitors; Female; Forearm; Hemodynamics; Humans; Inhalation Exposure; Male; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrites; Time Factors; Vascular Resistance; Vascular Stiffness; Vasoconstriction; Vasodilation; Vasodilator Agents; Vehicle Emissions; Young Adult | 2013 |
L-arginine does not improve biochemical and hormonal response in trained runners after 4 weeks of supplementation.
Topics: Adult; Ammonia; Arginine; Cyclic GMP; Dietary Supplements; Double-Blind Method; Exercise; Female; Hormones; Human Growth Hormone; Humans; Hydrocortisone; Insulin; Insulin-Like Growth Factor I; Lactic Acid; Male; Nitrates; Nitric Oxide; Nitrites; Placebos; Running | 2014 |
Effects of acute supplementation of L-arginine and nitrate on endurance and sprint performance in elite athletes.
Topics: Adolescent; Arginine; Athletes; Athletic Performance; Blood Pressure; Dietary Supplements; Double-Blind Method; Humans; Male; Nitrates; Nitric Oxide; Nitrites; Running | 2015 |
Serum and cerebrospinal fluid concentrations of homoarginine, arginine, asymmetric and symmetric dimethylarginine, nitrite and nitrate in patients with multiple sclerosis and neuromyelitis optica.
Topics: Adult; Arginine; Female; Homoarginine; Humans; Male; Middle Aged; Multiple Sclerosis; Neuromyelitis Optica; Nitrates; Nitrites | 2015 |
Combined L-citrulline and glutathione supplementation increases the concentration of markers indicative of nitric oxide synthesis.
Topics: Adolescent; Adult; Animals; Arginine; Biomarkers; Body Mass Index; Citrulline; Cyclic GMP; Dietary Supplements; Double-Blind Method; Glutathione; Healthy Volunteers; Human Umbilical Vein Endothelial Cells; Humans; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Resistance Training; Young Adult | 2015 |
Effects of chronic oral L-arginine administration on the L-arginine/NO pathway in patients with peripheral arterial occlusive disease or coronary artery disease: L-Arginine prevents renal loss of nitrite, the major NO reservoir.
Topics: Adult; Aged; Arginine; Double-Blind Method; Female; Humans; Kidney Tubules, Proximal; Male; Middle Aged; Nitrates; Nitric Oxide; Nitrites; Peripheral Arterial Disease | 2015 |
Acute supplementation of L-arginine affects neither strength performance nor nitric oxide production.
Topics: Adult; Arginine; Athletic Performance; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Exercise; Humans; Male; Muscle, Skeletal; Nitric Oxide; Nitrites; Resistance Training; Young Adult | 2018 |
Dietary Plant Sterols Supplementation Increases In Vivo Nitrite and Nitrate Production in Healthy Adults: A Randomized, Controlled Study.
Topics: Adult; Arginine; Cholesterol; Cross-Over Studies; Dietary Supplements; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Middle Aged; Nitrates; Nitrites; Phytosterols; Young Adult | 2017 |
Associations of Plasma Nitrite, L-Arginine and Asymmetric Dimethylarginine With Morbidity and Mortality in Patients With Necrotizing Soft Tissue Infections.
Topics: Adult; Aged; Arginine; Biomarkers; Disease-Free Survival; Female; Hospital Mortality; Humans; Male; Middle Aged; Nitrites; Prospective Studies; Severity of Illness Index; Shock, Septic; Soft Tissue Infections; Survival Rate; Time Factors | 2018 |
Short-Term Supplementation of Sodium Nitrate vs. Sodium Chloride Increases Homoarginine Synthesis in Young Men Independent of Exercise.
Topics: Arginine; Citrulline; Creatine; Creatinine; Dietary Supplements; Glutamates; Glutamine; Glycine; Homoarginine; Humans; Lysine; Male; Malondialdehyde; Methyltransferases; Nitrates; Nitrites; Ornithine; Phenylalanine; Sarcosine; Sodium Chloride; Tryptophan; Tyrosine | 2022 |
713 other study(ies) available for arginine and nitrites
| Article | Year |
|---|---|
Synergism between interleukin-1 beta and interferon-gamma, an inducer of nitric oxide synthase, in rat lung fibroblasts.
Topics: Amino Acid Oxidoreductases; Analysis of Variance; Animals; Arginine; Cells, Cultured; Drug Synergism; Enzyme Induction; Fibroblasts; Interferon-gamma; Interleukin-1; Lipopolysaccharides; Lung; Male; Nitric Oxide Synthase; Nitrites; Rats; Rats, Wistar; Recombinant Proteins | 1992 |
NO accounts completely for the oxygenated nitrogen species generated by enzymic L-arginine oxygenation.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell-Free System; Cysteine; Electron Spin Resonance Spectroscopy; Endothelium, Vascular; Hydroxylamine; Hydroxylamines; In Vitro Techniques; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitrites; S-Nitrosothiols; Swine | 1992 |
Tetrahydrobiopterin synthesis. An absolute requirement for cytokine-induced nitric oxide generation by vascular smooth muscle.
Topics: Amino Acid Oxidoreductases; Animals; Aorta; Arginine; Biopterins; Cells, Cultured; Cytosol; Hypoxanthines; Interferon-gamma; Kinetics; Lipopolysaccharides; Male; Methotrexate; Muscle, Smooth, Vascular; Myoglobin; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Oxidation-Reduction; Oxygen Consumption; Pteridines; Pterins; Rats; Rats, Inbred F344; Recombinant Proteins | 1992 |
Pterins inhibit nitric oxide synthase activity in rat alveolar macrophages.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Biopterins; Cells, Cultured; Citrulline; Hypoxanthines; Interferon-gamma; Macrophages, Alveolar; Male; Nitric Oxide Synthase; Nitrites; Pteridines; Pterins; Rats; Rats, Wistar; Recombinant Proteins | 1992 |
The role of nitric oxide in endotoxic shock: effects of NG-monomethyl-L-arginine.
Topics: Alanine Transaminase; Animals; Arginine; Blood Pressure; Dexamethasone; Lipopolysaccharides; Male; Nitrates; Nitric Oxide; Nitrites; omega-N-Methylarginine; Penicillamine; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Shock, Septic | 1992 |
L-arginine as an antihypertensive agent.
Topics: Antihypertensive Agents; Arginine; Blood Pressure; Cardiac Output; Citrulline; Cushing Syndrome; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renovascular; Injections, Intravenous; Nitrates; Nitrites | 1992 |
Metabolism of glyceryl trinitrate to nitric oxide by endothelial cells and smooth muscle cells and its induction by Escherichia coli lipopolysaccharide.
Topics: Animals; Arginine; Blood Pressure; Cattle; Cells, Cultured; Cyclic GMP; Cycloheximide; Endothelium, Vascular; Escherichia coli; Hemodynamics; Humans; In Vitro Techniques; Lipopolysaccharides; Muscle, Smooth, Vascular; Nitric Oxide; Nitrites; Nitroglycerin; omega-N-Methylarginine; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats | 1992 |
Effect of systemic L-arginine administration on hemodynamics and nitric oxide release in man.
Topics: Adult; Amino Acids; Arginine; Blood Pressure; Cyclic GMP; Heart Rate; Hemodynamics; Hormones; Humans; Male; Nitric Oxide; Nitrites | 1992 |
Increases in NO2-/NO3- excretion in the urine as an indicator of the release of endothelium-derived relaxing factor during elevation of blood pressure.
Topics: Animals; Aorta, Thoracic; Arginine; Blood Pressure; Constriction; Male; Nitrates; Nitric Oxide; Nitrites; omega-N-Methylarginine; Rats; Rats, Inbred WKY; Time Factors | 1992 |
L-arginine-dependent killing of intracellular Ehrlichia risticii by macrophages treated with gamma interferon.
Topics: Animals; Arginine; Cyclic GMP; Deferoxamine; Ehrlichia; Female; Interferon-gamma; Macrophages; Mice; Nitric Oxide; Nitrites; Nitroprusside; omega-N-Methylarginine | 1992 |
L-arginine infusion induces hypotension and diuresis/natriuresis with concomitant increased urinary excretion of nitrite/nitrate and cyclic GMP in humans.
Topics: Adult; Arginine; Blood Pressure; Cyclic GMP; Diuresis; Heart Rate; Humans; Male; Natriuresis; Nitrates; Nitrites; Nitrogen Oxides; Vasodilation | 1992 |
Formation of nitric oxide hemoglobin in erythrocytes co-cultured with alveolar macrophages taken from bleomycin treated rats.
Topics: Animals; Arginine; Bleomycin; Cell Communication; Cells, Cultured; Erythrocytes; Hemoglobins; Inflammation; Leukemia L1210; Macrophages, Alveolar; Male; Mice; Nitric Oxide; Nitrites; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Spectrophotometry | 1992 |
Induction of nitric oxide synthase is a necessary precondition for expression of tumor necrosis factor-independent tumoricidal activity by activated macrophages.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Bone Marrow; Cell Line; Cell Survival; Cells, Cultured; Citrulline; Drug Resistance; Enterococcus faecalis; Escherichia coli; Kinetics; Lipopolysaccharides; Macrophage Activation; Macrophages; Male; Mast-Cell Sarcoma; Moraxella catarrhalis; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Onium Compounds; Peptidoglycan; Phagocytes; Rats; Rats, Inbred Strains; Tumor Necrosis Factor-alpha | 1992 |
Role of nitric oxide in the oxidant stress during ischemia/reperfusion injury of the liver.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Kupffer Cells; Liver; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Oxidants; Rats; Rats, Inbred F344; Reperfusion Injury; Stress, Physiological; Superoxides | 1992 |
Stimulation of the nitric oxide synthase pathway in human hepatocytes by cytokines and endotoxin.
Topics: Amino Acid Oxidoreductases; Arginine; Cyclic GMP; Cytokines; Endotoxins; Humans; Lipopolysaccharides; Liver; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Recombinant Proteins | 1992 |
Lipopolysaccharide and cytokines induce a macrophage-type of nitric oxide synthase in bovine retinal pigmented epithelial cells.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cattle; Cycloheximide; Dexamethasone; Enzyme Induction; Interferon-gamma; Interleukin-1; Kinetics; Lipopolysaccharides; Macrophages; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Pigment Epithelium of Eye; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1992 |
Microglial-produced nitric oxide and reactive nitrogen oxides mediate neuronal cell death.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Death; Cells, Cultured; Cerebellum; Cytokines; Female; Immunization; Immunohistochemistry; Neuroglia; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitrogen Oxides; Pregnancy; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1992 |
Nitric oxide and cyclic GMP formation induced by interleukin 1 beta in islets of Langerhans. Evidence for an effector role of nitric oxide in islet dysfunction.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Biological Transport; Cyclic GMP; Cycloheximide; Glucose; Interleukin-1; Islets of Langerhans; Male; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Oxidation-Reduction; Rats; Rats, Sprague-Dawley | 1992 |
Early loss of the tyrosyl radical in ribonucleotide reductase of adenocarcinoma cells producing nitric oxide.
Topics: Adenocarcinoma; Amino Acid Oxidoreductases; Animals; Arginine; Blotting, Western; Citrulline; Electron Spin Resonance Spectroscopy; Enzyme Induction; Free Radicals; Kinetics; Mammary Neoplasms, Experimental; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Ribonucleotide Reductases; Tumor Cells, Cultured; Tyrosine | 1992 |
Soybean trypsin inhibitor and beta-amylase induce alveolar macrophages to release nitrogen oxides.
Topics: Animals; Arginine; beta-Amylase; Cells, Cultured; Dexamethasone; Dose-Response Relationship, Drug; Hypoxanthines; Limulus Test; Macrophages, Alveolar; Male; Nitrites; Nitrogen Oxides; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Time Factors; Trypsin Inhibitors | 1992 |
Nitric oxide mediates suppression of T cell responses in murine Trypanosoma brucei infection.
Topics: Animals; Arginine; Concanavalin A; Immune Tolerance; Lymphocyte Activation; Mice; Mice, Inbred C3H; Nitric Oxide; Nitrites; omega-N-Methylarginine; Spleen; T-Lymphocytes; Trypanosoma brucei brucei; Trypanosomiasis, African | 1992 |
A perfusion system for the long term study of macrophage activation.
Topics: Animals; Arginine; Cell Line; Dexamethasone; Dose-Response Relationship, Drug; Interferon-gamma; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Nitrites; Ornithine; Perfusion | 1992 |
Killing of Legionella pneumophila by nitric oxide in gamma-interferon-activated macrophages.
Topics: Animals; Arginine; Cell Line; Humans; Infant; Interferon-gamma; Iron; Legionella pneumophila; Leukemia, Promyelocytic, Acute; Macrophage Activation; Macrophages; Mice; Nitric Oxide; Nitrites; Nitroprusside; omega-N-Methylarginine; Recombinant Proteins; Tumor Cells, Cultured | 1992 |
In vivo induction of nitrite and nitrate by tumor necrosis factor, lymphotoxin, and interleukin-1: possible roles in malaria.
Topics: Animals; Arginine; Female; Interleukin-1; Lymphotoxin-alpha; Malaria; Male; Mice; Mice, Inbred CBA; Nitrates; Nitric Oxide; Nitrites; omega-N-Methylarginine; Tumor Necrosis Factor-alpha | 1992 |
Tumoricidal properties of rat peritoneal macrophages activated with various activators depend on nitrogen oxid synthesis.
Topics: Animals; Arginine; Cells, Cultured; Chromium Radioisotopes; Culture Media; Female; Immunotherapy; Interferon-gamma; Interleukin-2; Lipopolysaccharides; Macrophage Activation; Macrophages; Neoplasms, Experimental; Nitrites; Peritoneal Cavity; Rats; Rats, Inbred Lew; Recombinant Proteins; Tetradecanoylphorbol Acetate; Zymosan | 1992 |
Killing of virulent Mycobacterium tuberculosis by reactive nitrogen intermediates produced by activated murine macrophages.
Topics: Animals; Arginine; Blood Bactericidal Activity; Cytotoxicity, Immunologic; Female; Hydrogen Peroxide; Interferon-gamma; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Mice, Inbred BALB C; Mycobacterium tuberculosis; Nitrites; Nitrogen Dioxide; Nitrogen Oxides; Tumor Necrosis Factor-alpha | 1992 |
Production of nitrite by neonatal rat microglial cells/brain macrophages.
Topics: Animals; Animals, Newborn; Arginine; Brain; Cells, Cultured; Cytotoxicity, Immunologic; Interferon-gamma; Lipopolysaccharides; Macrophages; Nitric Oxide; Nitrites; omega-N-Methylarginine; Rats | 1992 |
L-arginine transport is increased in macrophages generating nitric oxide.
Topics: Animals; Arginine; Biological Transport; Cells, Cultured; Extracellular Space; Interferon-gamma; Kinetics; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; Nitrites; Recombinant Proteins | 1992 |
Serum NO2-/NO3- from oxidative L-arginine metabolism: a possible marker for small bowel allograft rejection.
Topics: Animals; Arginine; Biomarkers; Cyclosporine; Graft Rejection; Intestine, Small; Nitrates; Nitrites; Rats; Rats, Inbred ACI; Rats, Inbred Lew; Transplantation, Homologous; Transplantation, Isogeneic | 1992 |
Effector molecules from antitumor macrophages induced with OK-432 and cyclophosphamide.
Topics: Animals; Arginine; Cell Adhesion; Cell Division; Culture Media; Cyclophosphamide; Immunity, Cellular; In Vitro Techniques; Lymphoma; Macrophage Activation; Macrophages; Mice; Nitric Oxide; Nitrites; Picibanil; Tumor Cells, Cultured | 1992 |
Transforming growth factor-beta 1 inhibits L-arginine-derived relaxing factor(s) from smooth muscle cells.
Topics: Animals; Arginine; Biological Assay; Interleukin-1; Muscle, Smooth; Nitrites; Nitroarginine; Stereoisomerism; Transforming Growth Factor beta; Vasodilator Agents | 1992 |
Nitrite and nitrosamine synthesis by hepatocytes isolated from normal woodchucks (Marmota monax) and woodchucks chronically infected with woodchuck hepatitis virus.
Topics: Animals; Arginine; Carcinogens; Cells, Cultured; Female; Hepadnaviridae; Hepatitis, Viral, Animal; Indomethacin; Kinetics; Lipopolysaccharides; Liver; Male; Marmota; Nitrites; Nitrosamines; omega-N-Methylarginine; Rats | 1992 |
Nitrite activates the transcription of the Pseudomonas aeruginosa nitrite reductase and cytochrome c-551 operon under anaerobic conditions.
Topics: Anaerobiosis; Arginine; Bacterial Proteins; Cytochrome c Group; Gene Expression Regulation, Bacterial; Nitrate Reductase; Nitrate Reductases; Nitrates; Nitrites; Operon; Promoter Regions, Genetic; Pseudomonas aeruginosa; Transcription, Genetic | 1991 |
Interleukin-1 beta-induced formation of EPR-detectable iron-nitrosyl complexes in islets of Langerhans. Role of nitric oxide in interleukin-1 beta-induced inhibition of insulin secretion.
Topics: Animals; Arginine; Cells, Cultured; Electron Spin Resonance Spectroscopy; Interleukin-1; Iron-Sulfur Proteins; Islets of Langerhans; Kinetics; Male; Nitric Oxide; Nitrites; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Recombinant Proteins | 1991 |
Interleukin 1 induces prolonged L-arginine-dependent cyclic guanosine monophosphate and nitrite production in rat vascular smooth muscle cells.
Topics: Aminoquinolines; Animals; Arginine; Cells, Cultured; Cyclic GMP; Enzyme Activation; Guanylate Cyclase; Hemoglobins; Interleukin-1; Methylene Blue; Muscle, Smooth, Vascular; Nitrites; omega-N-Methylarginine; Protein Synthesis Inhibitors; Rats | 1991 |
A new relaxing factor in supernatant of incubated rat peritoneal neutrophils.
Topics: Animals; Aorta; Arginine; Drug Stability; Guanylate Cyclase; Neutrophils; Nitric Oxide; Nitrites; omega-N-Methylarginine; Peritoneal Cavity; Rats; Vasoconstriction; Vasodilation | 1991 |
Role of reactive nitrogen intermediate production in alveolar macrophage-mediated cytostatic activity induced by bleomycin lung damage in rats.
Topics: Aconitate Hydratase; Animals; Arginine; Bleomycin; Cytotoxicity, Immunologic; DNA Replication; Kinetics; Leukemia L1210; Lung; Macrophage Activation; Macrophages; Male; Mice; Nitriles; Nitrites; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Reference Values | 1990 |
Inhibition of tumor cell ribonucleotide reductase by macrophage-derived nitric oxide.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Line; Copper; Copper Sulfate; Ferredoxins; Gas Chromatography-Mass Spectrometry; Hydroxyurea; Interferon-gamma; Kinetics; Leukemia L1210; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Ribonucleotide Reductases | 1991 |
Glucocorticoids inhibit the induction of nitric oxide synthase and the related cell damage in adenocarcinoma cells.
Topics: Amino Acid Oxidoreductases; Arginine; Cell Survival; Cortodoxone; Dexamethasone; Enzyme Induction; Humans; Hydrocortisone; Kinetics; Lipopolysaccharides; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Progesterone; Tumor Cells, Cultured | 1991 |
Independence of the pattern of early cytokine release from autoregulation by nitric oxide.
Topics: Adenocarcinoma; Animals; Arginine; Culture Media; Cytokines; Female; Homeostasis; Interferon-gamma; L Cells; Lipopolysaccharides; Macrophage Activation; Macrophages; Male; Mammary Neoplasms, Experimental; Mice; Nitric Oxide; Nitrites; omega-N-Methylarginine; Peritoneal Cavity; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1991 |
L-arginine-dependent production of nitrogen oxides by rat pulmonary macrophages.
Topics: Animals; Arginine; Cells, Cultured; Cycloheximide; Interferon-gamma; Lipopolysaccharides; Macrophages, Alveolar; Male; Nitric Oxide; Nitrites; Nitrogen Oxides; Rats; Rats, Inbred Strains; Recombinant Proteins; Time Factors; Zymosan | 1991 |
Killing of Leishmania parasites in activated murine macrophages is based on an L-arginine-dependent process that produces nitrogen derivatives.
Topics: Animals; Arginine; Iron; Leishmania; Macrophage Activation; Macrophages; Mice; Nitrites; Nitrogen Oxides; Superoxides | 1991 |
Phagocytosis of Leishmania enhances macrophage activation by IFN-gamma and lipopolysaccharide.
Topics: Animals; Arginine; Cytotoxicity, Immunologic; Dinoprostone; Immunity, Cellular; Interferon-gamma; Leishmania; Leishmaniasis; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Mice, Inbred C3H; Mice, Inbred CBA; Nitrites; Pentose Phosphate Pathway; Phagocytosis; Recombinant Proteins | 1991 |
Tumor necrosis factor and granulocyte macrophage-colony stimulating factor stimulate human macrophages to restrict growth of virulent Mycobacterium avium and to kill avirulent M. avium: killing effector mechanism depends on the generation of reactive nitr
Topics: Arginase; Arginine; Drug Synergism; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Immunity, Cellular; Interferon-gamma; Macrophages; Mycobacterium avium; Nitrites; omega-N-Methylarginine; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 1991 |
Activated macrophage conditioned medium: identification of the soluble factors inducing cytotoxicity and the L-arginine dependent effector mechanism.
Topics: Aconitate Hydratase; Adenocarcinoma; Animals; Arginine; Blotting, Western; Chromatography, Gel; Culture Media; DNA; Dose-Response Relationship, Drug; Female; Immunity, Cellular; Interferon-gamma; Lipopolysaccharides; Macrophage Activation; Macrophages; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Nitrites; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1991 |
Macrophage cytostatic effect on Trypanosoma musculi involves an L-arginine-dependent mechanism.
Topics: Animals; Arginine; Female; Interferon-gamma; Iron; Macrophages; Mice; Mice, Inbred C57BL; Mycobacterium bovis; Nitric Oxide; Nitrites; omega-N-Methylarginine; Trypanosoma; Tumor Necrosis Factor-alpha | 1991 |
Interferon-gamma-treated murine macrophages inhibit growth of tubercle bacilli via the generation of reactive nitrogen intermediates.
Topics: Animals; Arginine; Interferon-gamma; Macrophage Activation; Macrophages; Mice; Mice, Inbred BALB C; Mycobacterium tuberculosis; Nitrites; Nitrogen Oxides; Oxygen; Peritoneal Cavity; Recombinant Proteins | 1991 |
Potentiation of tumor necrosis factor-alpha-mediated cytotoxicity of mast cells by their production of nitric oxide.
Topics: Animals; Arginine; Cytotoxicity, Immunologic; Drug Synergism; Immunity, Cellular; Mast Cells; Nitrates; Nitric Oxide; Nitrites; Platelet Aggregation; Rats; Rats, Inbred Strains; Tumor Necrosis Factor-alpha | 1991 |
Glomerular nitrite synthesis in in situ immune complex glomerulonephritis in the rat.
Topics: Animals; Antigen-Antibody Complex; Arginine; Cells, Cultured; Dexamethasone; Glomerulonephritis; Hemodynamics; Immunoglobulin G; Kidney Glomerulus; Lipopolysaccharides; Macrophages; Male; Nitrites; omega-N-Methylarginine; Perfusion; Rats; Rats, Inbred Lew | 1991 |
L-arginine-dependent nitric oxide formation and nitrite release in bone marrow-derived macrophages stimulated with bacterial lipopeptide and lipopolysaccharide.
Topics: Animals; Arginine; Bone Marrow Cells; Cells, Cultured; Cytosol; Enzyme Activation; Guanylate Cyclase; Lipopolysaccharides; Lipoproteins; Macrophage Activation; Macrophages; Mice; Mice, Inbred BALB C; Nitric Oxide; Nitrites | 1990 |
Tumor necrosis factor alpha activates soluble guanylate cyclase in bovine glomerular mesangial cells via an L-arginine-dependent mechanism.
Topics: Animals; Arginine; Cattle; Cells, Cultured; Cyclic GMP; Cycloheximide; Dactinomycin; Enzyme Activation; Glomerular Mesangium; Guanylate Cyclase; Humans; Interferon-gamma; Interleukin-1; Kinetics; Nitrates; Nitrites; omega-N-Methylarginine; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1990 |
L-arginine-dependent destruction of intrahepatic malaria parasites in response to tumor necrosis factor and/or interleukin 6 stimulation.
Topics: Animals; Arginine; Cells, Cultured; In Vitro Techniques; Interleukin-6; Liver; Nitrites; omega-N-Methylarginine; Plasmodium yoelii; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1991 |
The interaction of macrophages and bacteria: a comparative study of the induction of tumoricidal activity and of reactive nitrogen intermediates.
Topics: Animals; Arginine; Blood Bactericidal Activity; Cytotoxicity, Immunologic; Gram-Negative Bacteria; Immunity, Cellular; Macrophage Activation; Macrophages; Nitrites; Rats; Tumor Cells, Cultured | 1991 |
Suppression of lymphocyte proliferation through the nitric oxide synthesizing pathway.
Topics: Animals; Arginase; Arginine; Cell Adhesion; Cells, Cultured; Concanavalin A; Hemoglobins; In Vitro Techniques; Lymphocyte Activation; Lymphocytes; Mice; Nitric Oxide; Nitrites; omega-N-Methylarginine; Rats; Spleen; Urea | 1991 |
L-arginine-dependent production of a reactive nitrogen intermediate by macrophages of a uricotelic species.
Topics: Animals; Arginine; Cell Line; Chickens; Female; Immunity; Macrophages; Nitric Oxide; Nitrites; omega-N-Methylarginine | 1991 |
Activated macrophages destroy intracellular Leishmania major amastigotes by an L-arginine-dependent killing mechanism.
Topics: Animals; Arginine; Cytotoxicity, Immunologic; Immunity, Cellular; Interferon-gamma; Leishmania tropica; Macrophage Activation; Macrophages; Male; Mice; Mice, Inbred C3H; Nitric Oxide; Nitrites; omega-N-Methylarginine | 1990 |
Endothelial cell production of nitrogen oxides in response to interferon gamma in combination with tumor necrosis factor, interleukin-1, or endotoxin.
Topics: Animals; Arginine; Cells, Cultured; Endothelium, Vascular; Hypotension; Interferon-gamma; Interleukin-1; Mice; Monokines; Nitric Oxide; Nitrites; Tumor Necrosis Factor-alpha | 1990 |
Basal and stimulated formation and release of L-arginine-derived nitrogen oxides from cultured endothelial cells.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Arginine; Bradykinin; Calcimycin; Canavanine; Cattle; Cells, Cultured; Endothelium; Nitrates; Nitric Oxide; Nitrites; Nitrogen Oxides | 1990 |
Alterations of ribonucleotide reductase activity following induction of the nitrite-generating pathway in adenocarcinoma cells.
Topics: Adenocarcinoma; Animals; Arginine; Cell Line; Dactinomycin; DNA Replication; Interferon-gamma; Interleukin-1; Kinetics; Lipopolysaccharides; Mammary Neoplasms, Experimental; Mice; Nitrites; omega-N-Methylarginine; Recombinant Proteins; Ribonucleotide Reductases; Thymidine; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1990 |
Human alveolar and peritoneal macrophages mediate fungistasis independently of L-arginine oxidation to nitrite or nitrate.
Topics: Arginine; Cells, Cultured; Cryptococcus neoformans; Endotoxins; Escherichia coli; Humans; In Vitro Techniques; Interferon-gamma; Macrophages; Nitrates; Nitrites; Oxidation-Reduction; Peritoneal Cavity; Pulmonary Alveoli; Recombinant Proteins | 1990 |
Leishmania major amastigotes initiate the L-arginine-dependent killing mechanism in IFN-gamma-stimulated macrophages by induction of tumor necrosis factor-alpha.
Topics: Animals; Antibodies, Monoclonal; Arginine; Cytotoxicity, Immunologic; Interferon-gamma; Leishmania tropica; Leishmaniasis; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Mice, Inbred C3H; Nitrites; Signal Transduction; Time Factors; Tumor Necrosis Factor-alpha | 1990 |
Tumor necrosis factor-alpha synergizes with IFN-gamma in mediating killing of Leishmania major through the induction of nitric oxide.
Topics: Animals; Arginine; Cytotoxicity, Immunologic; Drug Synergism; Hydrogen Peroxide; Immunity, Cellular; Interferon-gamma; Leishmania tropica; Leishmaniasis; Macrophages; Mice; Mice, Inbred CBA; Nitric Oxide; Nitrites; omega-N-Methylarginine; Superoxides; Tumor Necrosis Factor-alpha | 1990 |
Cloned murine T lymphocytes synthesize a molecule with the biological characteristics of nitric oxide.
Topics: Animals; Arginine; Cell Line; Clone Cells; Cyclic GMP; Nitric Oxide; Nitrites; Platelet Aggregation; Rats; T-Lymphocytes; Thrombin | 1990 |
Modulation of nitrogen oxide synthesis in vivo: NG-monomethyl-L-arginine inhibits endotoxin-induced nitrate/nitrate biosynthesis while promoting hepatic damage.
Topics: Animals; Arginine; Female; Lipopolysaccharides; Liver; Mice; Mice, Inbred BALB C; Nitrates; Nitrites; Nitrogen Oxides; omega-N-Methylarginine; Propionibacterium acnes | 1990 |
Expression of cellular effector functions and production of reactive nitrogen intermediates: a comparative study including T lymphocytes, T-like cells, neutrophil granulocytes, and mononuclear phagocytes.
Topics: Animals; Arginine; Clone Cells; Humans; In Vitro Techniques; Macrophages; Mice; Neutrophils; Nitric Oxide; Nitrites; Nitrogen; Rats; T-Lymphocytes | 1990 |
L-arginine and arginine analogues: effects on isolated blood vessels and cultured endothelial cells.
Topics: Animals; Arginine; Cattle; Citrulline; Endothelium, Vascular; Guanethidine; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nitrites; Nitrogen Oxides; omega-N-Methylarginine; Ornithine; Rabbits; Rats; Rats, Inbred Strains; Stereoisomerism; Swine | 1990 |
L-arginine-dependent reactive nitrogen intermediates as mediators of tumor cell killing by activated macrophages.
Topics: Animals; Arginine; Bone Marrow Cells; Cell Survival; Culture Media; Macrophage Activation; Macrophages; Male; Nitrites; Phagocytosis; Rats; Tumor Cells, Cultured | 1990 |
Cytolytic mechanisms of activated macrophages. Tumor necrosis factor and L-arginine-dependent mechanisms act synergistically as the major cytolytic mechanisms of activated macrophages.
Topics: Animals; Arginine; Catalase; Clone Cells; Cytotoxicity, Immunologic; Drug Synergism; In Vitro Techniques; Macrophage Activation; Macrophages; Mice; Mice, Inbred DBA; Nitrites; Peritoneal Cavity; Trypsin Inhibitors; Tumor Necrosis Factor-alpha | 1990 |
Microbiostatic effect of murine-activated macrophages for Toxoplasma gondii. Role for synthesis of inorganic nitrogen oxides from L-arginine.
Topics: Animals; Arginine; Citrulline; Macrophage Activation; Macrophages; Mice; Mice, Inbred BALB C; Nitrates; Nitrites; Nitrogen Oxides; omega-N-Methylarginine; Toxoplasma | 1990 |
Temporal expression of different pathways of 1-arginine metabolism in healing wounds.
Topics: Animals; Arginase; Arginine; Cells, Cultured; Citrulline; Hydrolases; In Vitro Techniques; Macrophages; Male; Neutrophils; Nitrites; Ornithine; Rats; Urea; Wound Healing | 1990 |
Metabolic fate of L-arginine in relation to microbiostatic capability of murine macrophages.
Topics: Animals; Arginine; Carbon Radioisotopes; Cells, Cultured; Cryptococcus neoformans; Escherichia coli; Kinetics; Macrophages; Mice; Mycobacterium bovis; Nitrates; Nitrites; Phagocytosis; Radioisotope Dilution Technique; Urea | 1990 |
Nitrosation by stimulated macrophages. Inhibitors, enhancers and substrates.
Topics: Arginine; Ascorbic Acid; Cell Line; Hydrogen-Ion Concentration; Interferon-gamma; Lipopolysaccharides; Macrophages; Nitrates; Nitrites; Nitroso Compounds | 1989 |
Antiproliferative activity of gamma-interferon combined with lipopolysaccharide on murine adenocarcinoma: dependence on an L-arginine metabolism with production of nitrite and citrulline.
Topics: Adenocarcinoma; Animals; Arginine; Cell Division; Citrulline; Interferon-gamma; Kinetics; Lipopolysaccharides; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Nitrites; Recombinant Proteins; Tumor Cells, Cultured | 1989 |
Macrophage oxidation of L-arginine to nitric oxide, nitrite, and nitrate. Tetrahydrobiopterin is required as a cofactor.
Topics: Animals; Arginine; Biopterins; Cell Line; Chromatography, High Pressure Liquid; Citrulline; Cytosol; Kinetics; Macrophages; NADP; Nitrates; Nitric Oxide; Nitrites; Oxidation-Reduction | 1989 |
Regulation of macrophage physiology by L-arginine: role of the oxidative L-arginine deiminase pathway.
Topics: Animals; Arginine; Cell Survival; Cells, Cultured; Electron Transport; Hydrolases; Macrophages; Male; Mice; Nitrites; omega-N-Methylarginine; Peritoneal Cavity; Rats; Rats, Inbred F344 | 1989 |
Kupffer cell cytotoxicity to hepatocytes in coculture requires L-arginine.
Topics: Animals; Arginine; Aspartate Aminotransferases; Cell Survival; Cells, Cultured; Citrulline; Infections; Kupffer Cells; Lipopolysaccharides; Liver; Male; Nitrates; Nitrites; omega-N-Methylarginine; Protein Biosynthesis; Rats; Rats, Inbred Strains | 1989 |
Macrophage cytotoxicity against schistosomula of Schistosoma mansoni involves arginine-dependent production of reactive nitrogen intermediates.
Topics: Animals; Arginine; Cell-Free System; Cytotoxicity, Immunologic; Female; Iron; Larva; Macrophage Activation; Mice; Mice, Inbred C57BL; Mitochondria; Nitrites; Oxygen Consumption; Schistosoma mansoni | 1989 |
Evidence that activation of Kupffer cells results in production of L-arginine metabolites that release cell-associated iron and inhibit hepatocyte protein synthesis.
Topics: Animals; Arginine; Citrulline; Culture Media; Iron; Kupffer Cells; Lipopolysaccharides; Liver; Male; Nitrates; Nitrites; Protein Biosynthesis; Proteins; Rats | 1989 |
Activated murine macrophages secrete a metabolite of arginine with the bioactivity of endothelium-derived relaxing factor and the chemical reactivity of nitric oxide.
Topics: Animals; Aorta; Arginine; Biological Assay; Biological Factors; Chemical Phenomena; Chemistry; Endothelium, Vascular; Ferredoxins; Macrophage Activation; Macrophages; Mice; Mice, Inbred C3H; Muscle Relaxation; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitrites; Nitrogen Dioxide; Rabbits; Spectrophotometry | 1989 |
Macrophage synthesis of nitrite, nitrate, and N-nitrosamines: precursors and role of the respiratory burst.
Topics: Arginine; Citrulline; Humans; Hydrogen Peroxide; Macrophage Activation; Macrophages; Morpholines; Nitrates; Nitrites; Nitrosamines; Superoxides | 1987 |
An L-arginine-dependent mechanism mediates Kupffer cell inhibition of hepatocyte protein synthesis in vitro.
Topics: Animals; Arginine; Citrulline; In Vitro Techniques; Kupffer Cells; Lipopolysaccharides; Liver; Nitrates; Nitrites; Protein Biosynthesis; Rats; Rats, Inbred Strains | 1989 |
Interferon-gamma and tumor necrosis factor induce the L-arginine-dependent cytotoxic effector mechanism in murine macrophages.
Topics: Acetylmuramyl-Alanyl-Isoglutamine; Aconitate Hydratase; Animals; Antigen-Antibody Reactions; Arginine; Cell Line; Cytotoxicity, Immunologic; Drug Synergism; In Vitro Techniques; Interferon-gamma; Iron-Sulfur Proteins; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Nitrates; Nitrites; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1988 |
Macrophage oxidation of L-arginine to nitrite and nitrate: nitric oxide is an intermediate.
Topics: Animals; Arginine; Cell Line; Cytosol; Isotope Labeling; Macrophage Activation; Macrophages; Nitrates; Nitric Oxide; Nitrites; Nitrogen Isotopes; Oxidation-Reduction | 1988 |
Cytokines induce an L-arginine-dependent effector system in nonmacrophage cells.
Topics: Animals; Arginine; Biological Products; Citrulline; Cytokines; Humans; Lipopolysaccharides; Mammary Neoplasms, Experimental; Nitrates; Nitrites; Tumor Cells, Cultured; Urea | 1988 |
Characterization of the active site structures of arginine kinase-substrate complexes. Water proton magnetic relaxation rates and electron paramagnetic resonance spectra of manganous-enzyme complexes with substrates and of a transition state analog.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arginine; Binding Sites; Creatine Kinase; Electron Spin Resonance Spectroscopy; Formates; Ligands; Magnetic Resonance Spectroscopy; Manganese; Muscles; Nephropidae; Nitrates; Nitrites; Osmolar Concentration; Phosphotransferases; Protein Conformation; Stereoisomerism; Structure-Activity Relationship; Temperature; Thiocyanates; Water | 1974 |
Interaction of manganous ion, substrates, and anions with arginine kinase. Magnetic relaxation rate studies of water protons and kinetic anion effects.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Anions; Arginine; Binding Sites; Creatine Kinase; Electron Spin Resonance Spectroscopy; Formates; Kinetics; Manganese; Muscles; Nephropidae; Nitrates; Nitrites; Phosphotransferases; Protein Binding; Stereoisomerism; Structure-Activity Relationship; Thiocyanates; Water | 1974 |
Reaction of reduced flavins with tetranitromethane.
Topics: Alkanes; Arginine; Catalysis; D-Amino-Acid Oxidase; Flavin Mononucleotide; Nitrites; Oxidation-Reduction; Oxygen Consumption; Spectrophotometry | 1971 |
Restoration of a single enzyme function in bifunctionally defective non-polar pyrimidine-3 mutants of Neurospora.
Topics: Acridines; Alleles; Arginine; Aspartic Acid; Bacteriological Techniques; Carbamates; Genetic Code; Genetic Complementation Test; Hydroxylamines; Models, Biological; Mutagens; Mutation; Neurospora; Nitrites; Nitrosoguanidines; Phosphotransferases; Pyrimidines; Transferases | 1972 |
The effects of specific auxotrophic mutations on the virulence of Aspergillus nidulans for mice.
Topics: Adenine; Amino Acids; Aminobenzoates; Animals; Arginine; Aspergillus; Aspergillus nidulans; Biotin; Hypoxanthines; Male; Methionine; Mice; Mutation; Nicotinic Acids; Nitrites; Ornithine; Proline; Purines; Pyridoxine; Riboflavin; Thiamine; Virulence; Vitamin B Complex | 1973 |
Null effect of concurrent feeding of sodium nitrite and amino acids to MRC rats.
Topics: Amino Acids; Animals; Arginine; Diet; Female; Hydroxyproline; Male; Neoplasms, Experimental; Nitrites; Nitrosamines; Nitroso Compounds; Proline; Pyrrolidines; Rats; Sodium | 1973 |
A change in the specificity of transfer RNA after partial deamination with nitrous acid.
Topics: Acids; Arginine; Binding Sites; Carbon Isotopes; Chromatography; Escherichia coli; Genetic Code; Glycine; Nitrites; RNA, Bacterial; RNA, Transfer | 1968 |
Chemotactic response to amino acids by Pseudomonas aeruginosa in a semisolid nitrate medium.
Topics: Agar; Alanine; Amino Acids; Arginine; Carbon Dioxide; Chemotaxis; Chromatography, Thin Layer; Culture Media; Densitometry; Electron Transport; Glutamates; Indicators and Reagents; Nitrates; Nitrites; Nitrogen; Pseudomonas aeruginosa | 1971 |
Failure to induce tumors in Swiss mice after concurrent administration of amino acids and sodium nitrite.
Topics: Adenoma; Animals; Arginine; Carcinogens; Female; Hydroxyproline; Lung Neoplasms; Male; Mice; Neoplasms, Experimental; Nitrites; Nitroso Compounds; Piperidines; Proline; Pyrrolidines | 1972 |
Kinetics of nitrosamide formation from alkylureas, N-alkylurethans, and alkylguanidines: possible implications for the etiology of human gastric cancer.
Topics: Arginine; Carcinogens; Chemical Phenomena; Chemistry; Citrulline; Diet; Guanidines; Humans; Kinetics; Nitrites; Nitroso Compounds; Nitrosoguanidines; Nitrosourea Compounds; Sodium; Spectrophotometry; Stomach Neoplasms; Urea; Urethane | 1971 |
Characterization of a new defective strain of TMV.
Topics: Amino Acid Sequence; Arginine; Chromatography, Ion Exchange; Chromatography, Paper; Cysteine; Defective Viruses; Methods; Microscopy, Electron; Nitrites; Tobacco Mosaic Virus; Trypsin; Viral Proteins | 1969 |
Stimulation of staphylococcal nitrate reductase production by chloramphenicol.
Topics: Arginine; Chloramphenicol; Nitrites; Oxidoreductases; Staphylococcus | 1966 |
Chemically induced methemoglobinemias in the mouse.
Topics: Acetophenones; Aniline Compounds; Animals; Arginine; Azides; Erythrocytes; Female; Hydroxylamines; In Vitro Techniques; Iproniazid; Methemoglobin; Methemoglobinemia; Methylene Blue; Mice; Nitrites; Nitrobenzenes; Phenols; Proadifen; Propiophenones; Rats; Toluene | 1967 |
Biochemical characterization of arginine muants in Schizosaccharomyces pombe and the possibility of repression.
Topics: Arginine; Ascomycota; Citrulline; Culture Media; Enzyme Repression; Mutation; Neurospora; Nitrites; Ornithine; Proline; Radiation Genetics; Succinates | 1967 |
Regulation of enzyme synthesis in the arginine deiminase pathway of Pseudomonas aeruginosa.
Topics: Arginine; Carbamates; Enzyme Induction; Hydrolases; Nitrates; Nitrites; Ornithine Carbamoyltransferase; Oxygen; Phosphotransferases; Phosphotransferases (Carboxyl Group Acceptor); Pseudomonas aeruginosa | 1980 |
Hemin activation of an inducible isoform of nitric oxide synthase in vascular smooth-muscle cells.
Topics: Analysis of Variance; Animals; Arginine; Cells, Cultured; Cycloheximide; Enzyme Activation; Enzyme Inhibitors; Hemin; Isoenzymes; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Protein Synthesis Inhibitors; Rats; Stimulation, Chemical | 1995 |
Nitro containing L-arginine analogs interfere with assays for nitrate and nitrite.
Topics: Animals; Arginine; Enzyme Inhibitors; Evaluation Studies as Topic; Guanidines; Luminescent Measurements; Macrophages, Alveolar; Male; Mice; Mice, Inbred BALB C; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrites; Nitroarginine; Ornithine; Rats; Rats, Sprague-Dawley; Triazines | 1995 |
L-arginine deficiency and hemodynamic changes as a result of arginase efflux following orthotopic liver transplantation.
Topics: Adult; Arginase; Arginine; Blood Pressure; Citrulline; Diastole; Female; Humans; Liver Transplantation; Male; Monitoring, Intraoperative; Nitrates; Nitrites; Ornithine; Pulmonary Wedge Pressure; Reperfusion | 1995 |
NMDA-dependent prostaglandin E2 release by human cultured astroglial cells is driven by nitric oxide.
Topics: Arachidonic Acid; Arginine; Astrocytes; Astrocytoma; Cell Line; Cyclic GMP; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Kinetics; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroprusside; Oxyhemoglobins; Receptors, N-Methyl-D-Aspartate; Tumor Cells, Cultured | 1995 |
The role of nitric oxide in hemodynamic and metabolic alterations induced by prostaglandin F2 alpha in the perfused rat liver.
Topics: Animals; Arginine; Bile; Dinoprost; Endotoxins; Enzyme Inhibitors; Escherichia coli; Glucose; Hemodynamics; Kinetics; Lactates; Lactic Acid; Liver; Male; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Perfusion; Rats; Rats, Wistar; Urea | 1995 |
Role of nitric oxide in adenosine receptor-mediated relaxation of porcine coronary artery.
Topics: Aminoquinolines; Animals; Arginine; Coronary Vessels; Cyclic GMP; Male; Nitric Oxide; Nitrites; omega-N-Methylarginine; Receptors, Purinergic P1; Swine; Vasodilation; Vasodilator Agents | 1995 |
Biosynthesis of nitric oxide activates iron regulatory factor in macrophages.
Topics: Aconitate Hydratase; Adenocarcinoma; Amino Acid Oxidoreductases; Animals; Arginine; Cell Line; Cells, Cultured; Enzyme Induction; Interferon-gamma; Iron-Regulatory Proteins; Kinetics; Leukemia L1210; Lipopolysaccharides; Macrophage Activation; Macrophages, Peritoneal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mitochondria; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Recombinant Proteins; RNA-Binding Proteins; Tumor Cells, Cultured | 1993 |
Interleukin 1 activates soluble guanylate cyclase in human vascular smooth muscle cells through a novel nitric oxide-independent pathway.
Topics: Amino Acid Oxidoreductases; Aminoquinolines; Animals; Arginine; Base Sequence; Catecholamines; Cells, Cultured; Cyclic GMP; DNA Primers; Enzyme Activation; Guanylate Cyclase; Humans; Imidazolines; Interferon-gamma; Interleukin-1; Lipopolysaccharides; Methylene Blue; Molecular Sequence Data; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Polymerase Chain Reaction; Rats; RNA, Messenger; Tumor Necrosis Factor-alpha | 1994 |
Inhibition of nitric oxide formation by guanidines.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Cell Line; Guanidines; In Vitro Techniques; Interleukin-1; Male; Mesenteric Arteries; Methylguanidine; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Vasoconstriction | 1993 |
Human retinal pigmented epithelial cells produce nitric oxide in response to cytokines.
Topics: Amino Acid Oxidoreductases; Arginine; Cells, Cultured; Cycloheximide; Cytokines; Fibroblast Growth Factor 2; Humans; Interferon-gamma; Interleukin-1; Kinetics; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; omega-N-Methylarginine; Pigment Epithelium of Eye; Recombinant Proteins; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 1994 |
The role of nitric oxide in the pathogenesis of spontaneous murine autoimmune disease: increased nitric oxide production and nitric oxide synthase expression in MRL-lpr/lpr mice, and reduction of spontaneous glomerulonephritis and arthritis by orally admi
Topics: Administration, Oral; Amino Acid Oxidoreductases; Animals; Arginine; Arthritis; Autoimmune Diseases; Chromosome Mapping; Crosses, Genetic; Female; Glomerulonephritis; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine | 1994 |
An L-arginine-nitric oxide-cyclic guanosine monophosphate system exists in the uterus and inhibits contractility during pregnancy.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Citrulline; Culture Techniques; Cyclic GMP; Dose-Response Relationship, Drug; Female; Labor, Obstetric; Methylene Blue; NADP; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroprusside; Pregnancy; Progesterone; Rats; Rats, Sprague-Dawley; Uterine Contraction; Uterus | 1994 |
Inducible L-arginine-dependent nitric oxide synthase activity in bovine bone marrow-derived macrophages.
Topics: Amino Acid Oxidoreductases; Animals; Arginase; Arginine; Bacterial Physiological Phenomena; Bone Marrow Cells; Cattle; Enzyme Induction; Interferon-gamma; Macrophage Activation; Macrophages; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Tumor Necrosis Factor-alpha | 1994 |
Inhibition of nitric oxide synthase in experimental gram-negative sepsis.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Escherichia coli; Escherichia coli Infections; Liver; Mice; Nitrates; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Shock, Septic; Tumor Necrosis Factor-alpha | 1994 |
Inducible nitric oxide synthase is increased in murine lung epithelial cells by cytokine stimulation.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Line; Citrulline; Cytokines; Dexamethasone; Enzyme Induction; Epithelium; Guanidines; Interferon-gamma; Interleukin-1; Kinetics; Lung; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitrites; Recombinant Proteins; RNA, Messenger; Tumor Necrosis Factor-alpha | 1994 |
Is endotoxin-induced hypotension related to nitric oxide formation?
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Dogs; Endotoxins; Hemodynamics; Hypotension; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Oxygen; Random Allocation; Shock, Septic; Tumor Necrosis Factor-alpha | 1994 |
Exogenous NG-hydroxyl-L-arginine causes nitrite production in vascular smooth muscle cells in the absence of nitric oxide synthase activity.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Carrier Proteins; Cells, Cultured; Enzyme Induction; Male; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitrites; Rats; Rats, Wistar | 1994 |
Interferon-gamma and interleukin-1 beta induce nitric oxide formation from primary mouse astrocytes.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Astrocytes; Cerebral Cortex; Cycloheximide; Interferon-gamma; Interleukin-1; Lipopolysaccharides; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Precipitin Tests; Tumor Necrosis Factor-alpha | 1993 |
Nitric oxide synthase: an endogenous source of elevated nitrite in infected urine.
Topics: Amino Acid Oxidoreductases; Arginine; Chromatography, Thin Layer; Escherichia coli Infections; Female; Female Urogenital Diseases; Filtration; Humans; Infections; Male; Male Urogenital Diseases; NADP; Nitrates; Nitric Oxide Synthase; Nitrites; Osmolar Concentration; Reference Values; Urinary Tract Infections | 1994 |
Endogenous nitric oxide enhances prostaglandin production in a model of renal inflammation.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cholic Acids; Dinoprostone; Disease Models, Animal; Hydronephrosis; In Vitro Techniques; Indomethacin; Kidney; Male; Models, Biological; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Perfusion; Prostaglandin-Endoperoxide Synthases; Rabbits; Ureter | 1994 |
Nitric-oxide synthase assays.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Chromatography, Ion Exchange; Citrulline; Dithiothreitol; Hemoglobins; Indicators and Reagents; Mammals; NADP; Nitrates; Nitric Oxide Synthase; Nitrites; Pterins; Sensitivity and Specificity; Spectrophotometry | 1994 |
N-monomethyl arginine, an inhibitor of nitric oxide synthase, suppresses the development of adjuvant arthritis in rats.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Arthritis, Experimental; Disease Models, Animal; Male; Nitrates; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Rats; Rats, Inbred Lew | 1994 |
Role of vascular nitric oxide synthase in endotoxin shock of Propionibacterium acnes-sensitized rats.
Topics: Amino Acid Oxidoreductases; Animals; Aorta; Arginine; Blood Pressure; Cyclic GMP; Dexamethasone; Enzyme Induction; Heart Rate; Hepatectomy; Hypersensitivity; Lipopolysaccharides; Male; Nitrates; Nitric Oxide Synthase; Nitrites; Nitroarginine; Propionibacterium acnes; Rats; Rats, Wistar; Shock, Septic; Splenectomy; Survival Analysis; Tissue Distribution | 1994 |
Nitric oxide participates in the regulation of pancreatic acinar cell secretion.
Topics: Amino Acid Oxidoreductases; Amylases; Animals; Arginine; Carbachol; Cyclic AMP; In Vitro Techniques; Male; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; omega-N-Methylarginine; Pancreas; Rats; Rats, Wistar | 1994 |
Detrimental effect of nitric oxide synthase inhibition during endotoxemia may be caused by high levels of tumor necrosis factor and interleukin-6.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Endotoxins; Interleukin-6; Male; Nitrates; Nitric Oxide Synthase; Nitrites; Nitroarginine; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 1994 |
Expression of inducible nitric oxide in human lung epithelial cells.
Topics: Amino Acid Oxidoreductases; Arginine; Blotting, Northern; Bronchi; Cell Line; Cells, Cultured; Cytokines; Dexamethasone; Enzyme Induction; Epithelium; Gene Expression; Humans; Kinetics; Lung; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Recombinant Proteins; Trachea; Tumor Necrosis Factor-alpha | 1994 |
HIV coating gp 120 glycoprotein-dependent prostaglandin E2 release by human cultured astrocytoma cells is regulated by nitric oxide formation.
Topics: Amino Acid Oxidoreductases; Arginine; Astrocytoma; Cell Line; Dinoprostone; Dose-Response Relationship, Drug; HIV Envelope Protein gp120; Humans; Indomethacin; Kinetics; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroprusside; Tumor Cells, Cultured | 1994 |
Nitric oxide is involved in control of Trypanosoma cruzi-induced parasitemia and directly kills the parasite in vitro.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Chagas Disease; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; omega-N-Methylarginine; Spleen; Trypanosoma cruzi | 1994 |
The morphogenic/cytotoxic and prostaglandin-stimulating activities of interleukin-1 beta in the rat ovary are nitric oxide independent.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cells, Cultured; Dinoprostone; Female; Guanidines; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; L-Lactate Dehydrogenase; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroprusside; omega-N-Methylarginine; Ovary; Rats; Rats, Sprague-Dawley; Sialoglycoproteins; Transforming Growth Factor beta | 1994 |
Endogenous nitric oxide synthesis determines sensitivity to the pressor effect of salt.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Hypertension; Kidney Glomerulus; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitrogen Dioxide; Proteinuria; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary | 1994 |
Arginine metabolism in experimental glomerulonephritis: interaction between nitric oxide synthase and arginase.
Topics: Amino Acid Oxidoreductases; Animals; Arginase; Arginine; Cells, Cultured; Glomerular Mesangium; Glomerulonephritis; Humans; Immunoglobulin G; Kidney Glomerulus; Kinetics; Lipopolysaccharides; Macrophages; Male; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Rats; Rats, Inbred Lew; Reference Values; Urea | 1994 |
Interleukin-1 beta stimulates nitrite production in the rat ovary: evidence for heterologous cell-cell interaction and for insulin-mediated regulation of the inducible isoform of nitric oxide synthase.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Communication; Cell Count; Culture Media; Culture Techniques; Female; Insulin; Interleukin-1; Kinetics; Nitric Oxide Synthase; Nitrites; Ovary; Rats; Receptors, Interleukin-1 | 1994 |
Heterogenous nitrite production by IL-4-stimulated human monocytes and peripheral blood mononuclear cells.
Topics: Amino Acid Oxidoreductases; Arginine; Cells, Cultured; Humans; Interferon-gamma; Interleukin-4; Leukocytes, Mononuclear; Monocytes; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Recombinant Proteins | 1994 |
Renal hemodynamic effects of dietary protein in the rat: role of nitric oxide.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cyclic GMP; Dietary Proteins; Glomerular Filtration Rate; Hemodynamics; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Sprague-Dawley; Vascular Resistance; Vasodilation | 1995 |
Hydrogen peroxide-supported oxidation of NG-hydroxy-L-arginine by nitric oxide synthase.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Benzene Derivatives; Cell Line; Citrulline; Hydrogen Peroxide; Kinetics; Macrophages; Mice; NADP; Nitrates; Nitric Oxide Synthase; Nitrites; Oxygen; Peroxides; tert-Butylhydroperoxide | 1995 |
Expression of inducible nitric oxide synthase causes delayed neurotoxicity in primary mixed neuronal-glial cortical cultures.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cells, Cultured; Cerebral Cortex; Interferon-gamma; Lipopolysaccharides; Nerve Degeneration; Nervous System Diseases; Neuroglia; Neurons; Nitric Oxide Synthase; Nitrites; Nitroarginine; Rats; Tacrolimus | 1994 |
Effects of nitric oxide synthase inhibition combined with nitric oxide inhalation in a porcine model of endotoxin shock.
Topics: Administration, Inhalation; Amino Acid Oxidoreductases; Animals; Arginine; Blood Gas Analysis; Escherichia coli; Hemodynamics; Hydrogen-Ion Concentration; Leukocyte Count; Lipopolysaccharides; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Platelet Count; Shock, Septic; Swine; Tumor Necrosis Factor-alpha | 1995 |
Lipopolysaccharide-induced changes in plasma nitrite and nitrate concentrations in rats and mice: pharmacological evaluation of nitric oxide synthase inhibitors.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Dexamethasone; Dose-Response Relationship, Drug; Guanidines; Lipopolysaccharides; Male; Mice; Mice, Inbred Strains; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Time Factors | 1995 |
Identification of constitutive and inducible forms of nitric oxide synthase in human platelets.
Topics: Amino Acid Oxidoreductases; Arginine; Blood Platelets; Citrulline; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Humans; Nitric Oxide Synthase; Nitrites; Nitroarginine; Platelet Aggregation; Polymerase Chain Reaction; RNA, Messenger; Transcription, Genetic | 1995 |
Pulmonary alveolar epithelial inducible NO synthase gene expression: regulation by inflammatory mediators.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood; Cells, Cultured; Cytokines; Epithelium; Female; Fluorescent Antibody Technique; Gene Expression Regulation, Enzymologic; Lipopolysaccharides; Nitrates; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Pregnancy; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Zymosan | 1995 |
Experimental pneumococcal meningitis: cerebrovascular alterations, brain edema, and meningeal inflammation are linked to the production of nitric oxide.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Arterioles; Brain Edema; Cells, Cultured; Cerebral Arteries; Cerebrospinal Fluid; Cerebrovascular Circulation; Endothelium, Vascular; Inflammation; Intracranial Pressure; Leukocyte Count; Male; Meningitis, Pneumococcal; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Rats; Rats, Wistar; Superoxide Dismutase | 1995 |
Amplification of nitric oxide synthase expression by nitric oxide in interleukin 1 beta-stimulated rat mesangial cells.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blotting, Northern; Cell Nucleus; Citrulline; Gene Expression Regulation, Enzymologic; Glomerular Mesangium; Interleukin-1; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroprusside; omega-N-Methylarginine; Penicillamine; Rats; RNA, Messenger; S-Nitroso-N-Acetylpenicillamine; Time Factors; Transcription, Genetic | 1995 |
Relation between pressure natriuresis and urinary excretion of nitrate/nitrite in anesthetized dogs.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Diuresis; Dogs; Natriuresis; Nitrates; Nitric Oxide Synthase; Nitrites; Nitroarginine; Renal Artery | 1995 |
Rapid induction of mRNA for nitric oxide synthase II in rat alveolar macrophages by intratracheal administration of Mycobacterium tuberculosis and Mycobacterium avium.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Base Sequence; Bronchoalveolar Lavage Fluid; Humans; Lung; Macrophages, Alveolar; Male; Molecular Sequence Data; Mycobacterium avium Complex; Mycobacterium tuberculosis; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tumor Necrosis Factor-alpha | 1995 |
Co-induction of arginase and nitric oxide synthase in murine macrophages activated by lipopolysaccharide.
Topics: Amino Acid Oxidoreductases; Animals; Antioxidants; Arginase; Arginine; Cell Line; Enzyme Induction; Interferon-gamma; Kinetics; Macrophages, Peritoneal; Mice; NF-kappa B; Nitrates; Nitric Oxide Synthase; Nitrites; Pyrrolidines; Recombinant Proteins; Thiocarbamates; Urea | 1995 |
Further characterization and comparison of inducible nitric oxide synthase in mouse, rat, and human hepatocytes.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Oxidoreductases; Animals; Arginine; Cells, Cultured; Cyclic GMP; Dexamethasone; Enzyme Induction; Gene Expression; Humans; Interferon-gamma; Interleukin-1; Interleukins; Isoenzymes; Lipopolysaccharides; Liver; Mice; Nitrates; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Rats; Recombinant Proteins; RNA, Messenger; Species Specificity; Tumor Necrosis Factor-alpha | 1995 |
Increase in serum NG-hydroxy-L-arginine in rats treated with bacterial lipopolysaccharide.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Citrulline; Escherichia coli; Lipopolysaccharides; Male; Nitrates; Nitric Oxide Synthase; Nitrites; Rats; Rats, Wistar; Stereoisomerism | 1995 |
Nitric oxide synthase activity in molluscan hemocytes.
Topics: Amino Acid Oxidoreductases; Animals; Antibodies; Arginine; Citrulline; Hemocytes; Kinetics; Nitrates; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Rabbits; Snails | 1995 |
Direct correlation between expression of endogenous inducible nitric oxide synthase and regression of M5076 reticulum cell sarcoma hepatic metastases in mice treated with liposomes containing lipopeptide CGP 31362.
Topics: Adjuvants, Immunologic; Amino Acid Oxidoreductases; Animals; Apoptosis; Arginine; Drug Carriers; Drug Interactions; Enzyme Activation; Enzyme Induction; Female; Interferon-gamma; Liposomes; Liver Neoplasms, Experimental; Lymphoma, Non-Hodgkin; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Oligopeptides; omega-N-Methylarginine; Peptide Fragments; Recombinant Proteins; RNA, Messenger | 1995 |
The inter-relationship between polyamines and the L-arginine nitric oxide pathway in the human placenta.
Topics: Amino Acid Oxidoreductases; Arginine; Cadaverine; Cell Line; Chorionic Villi; Female; Fetal Growth Retardation; Humans; Lipopolysaccharides; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Placenta; Polyamines; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, First; Pregnancy Trimester, Third; Putrescine; Reference Values; Spermidine; Spermine | 1995 |
Leukotoxin, 9,10-epoxy-12-octadecenoate causes edematous lung injury via activation of vascular nitric oxide synthase.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Vessels; Enzyme Activation; Exotoxins; L-Lactate Dehydrogenase; Linoleic Acids; Lung; Male; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Oxyhemoglobins; Perfusion; Pulmonary Edema; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 1995 |
Enhanced nitric oxide synthase activity in portal hypertensive rabbits.
Topics: Amino Acid Oxidoreductases; Animals; Aorta, Thoracic; Arginine; Calcium; Cyclic GMP; Endothelium, Vascular; Hemodynamics; Hypertension, Portal; Ligation; Male; Mesenteric Artery, Superior; NADPH Dehydrogenase; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Portal Vein; Rabbits | 1995 |
Nitric oxide production by Sertoli cells in response to cytokines and lipopolysaccharide.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cells, Cultured; Cytokines; Drug Interactions; Guanidines; Humans; Interferon-gamma; Interleukin-1; Lipopolysaccharides; Male; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Recombinant Proteins; RNA, Messenger; Sertoli Cells; Tumor Necrosis Factor-alpha | 1995 |
Transferrin induces nitric oxide synthase mRNA in rat cultured aortic smooth muscle cells.
Topics: Amino Acid Oxidoreductases; Animals; Aorta; Arginine; Base Sequence; Cells, Cultured; Culture Media; Cycloheximide; Humans; Molecular Sequence Data; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; RNA-Directed DNA Polymerase; RNA, Messenger; Transferrin | 1995 |
Erythrocyte stages of Plasmodium falciparum exhibit a high nitric oxide synthase (NOS) activity and release an NOS-inducing soluble factor.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Biological Factors; Canavanine; Cell Adhesion; Cells, Cultured; Citrulline; Culture Media, Conditioned; Cyclic GMP; Endothelium, Vascular; Enzyme Induction; Erythrocytes; Host-Parasite Interactions; Humans; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Plasmodium; Plasmodium falciparum; Protozoan Proteins; Species Specificity; Umbilical Veins | 1995 |
Reactive species in ischemic rat lung injury: contribution of peroxynitrite.
Topics: Animals; Arginine; Immunohistochemistry; Ischemia; Lung; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitrites; Perfusion; Pressure; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Staining and Labeling; Tyrosine | 1995 |
Nitric oxide synthase activity is inducible in rat, but not rabbit alveolar macrophages, with a concomitant reduction in arginase activity.
Topics: Amino Acid Oxidoreductases; Animals; Arginase; Arginine; Citrulline; Cytokines; Dexamethasone; Enzyme Induction; Female; In Vitro Techniques; Lipopolysaccharides; Macrophages, Alveolar; Male; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Ornithine; Rabbits; Rats; Rats, Sprague-Dawley | 1995 |
Inhibition of nitric oxide (NO.) production in murine macrophages by flavones.
Topics: Animals; Arginine; Cell Survival; Concanavalin A; Enzyme Inhibitors; Flavonoids; Genistein; Isoflavones; Lipopolysaccharides; Macrophages; Macrophages, Peritoneal; Male; Mice; Mice, Inbred BALB C; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine | 1995 |
Polydeoxyribonucleotides and nitric oxide release from guinea-pig hearts during ischaemia and reperfusion.
Topics: Acetylcholine; Animals; Arginine; Arrhythmias, Cardiac; Chemical Fractionation; Coronary Circulation; Disease Models, Animal; DNA; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibrinolytic Agents; Guinea Pigs; Male; Molecular Weight; Myocardial Reperfusion Injury; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Polydeoxyribonucleotides | 1995 |
A role for gamma interferon-induced nitric oxide in pulmonary clearance of Cryptococcus neoformans.
Topics: Animals; Arginine; Cells, Cultured; Cryptococcosis; Immunocompetence; Interferon-gamma; Leukocytes; Lung; Lymphocyte Activation; Macrophages; Mice; Mice, SCID; Nitrates; Nitric Oxide; Nitrites; omega-N-Methylarginine; Stem Cells | 1995 |
Coronary kinin generation mediates nitric oxide release after angiotensin receptor stimulation.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Arginine; Coronary Vessels; Data Interpretation, Statistical; Dogs; In Vitro Techniques; Kinins; Microcirculation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Peptide Fragments; Receptors, Angiotensin; Stimulation, Chemical | 1995 |
On-line measurement of nitric oxide generation in buffer-perfused rabbit lungs.
Topics: Animals; Arginine; Calcimycin; Female; In Vitro Techniques; Luminescent Measurements; Lung; Male; Nitrates; Nitric Oxide; Nitrites; omega-N-Methylarginine; Oxygen; Perfusion; Rabbits; Vanadium Compounds | 1995 |
Nitric oxide production by mononuclear leukocytes in alcoholic cirrhosis.
Topics: Alanine Transaminase; Arginine; Aspartate Aminotransferases; Bilirubin; Cells, Cultured; Female; Hepatitis, Alcoholic; Humans; Leukocytes, Mononuclear; Liver Cirrhosis, Alcoholic; Male; Middle Aged; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites | 1995 |
Endogenous and exogenous nitric oxide protect against intracoronary thrombosis and reocclusion after thrombolysis.
Topics: Animals; Arginine; Coronary Circulation; Coronary Thrombosis; Dogs; Electric Stimulation; Hematocrit; Nitric Oxide; Nitrites; Nitroarginine; Nitroprusside; Platelet Aggregation; Recurrence; Thrombolytic Therapy; Whole Blood Coagulation Time | 1995 |
Production of nitrite by primary rat astrocytes in response to pneumococci.
Topics: Animals; Animals, Newborn; Arginine; Astrocytes; Cells, Cultured; Cerebral Cortex; Nitric Oxide; Nitrites; Rats; Rats, Inbred Lew; Rats, Wistar; Streptococcus pneumoniae; Superoxide Dismutase | 1995 |
Oral administration of L-arginine and captopril in rats prevents chronic renal failure by nitric oxide production.
Topics: Administration, Oral; Animals; Arginine; Blood Pressure; Captopril; Creatinine; Female; Kidney Failure, Chronic; Male; Natriuresis; Nitrates; Nitric Oxide; Nitrites; Proteinuria; Rats; Rats, Sprague-Dawley | 1995 |
Detection of nitric oxide production in mice by spin-trapping electron paramagnetic resonance spectroscopy.
Topics: Animals; Arginine; Chelating Agents; Electron Spin Resonance Spectroscopy; Female; Ferrous Compounds; Kidney; Lipopolysaccharides; Liver; Mice; Mice, Inbred ICR; Nitrates; Nitric Oxide; Nitrites; Nitrogen Isotopes; omega-N-Methylarginine; Shock, Septic; Sorbitol; Spin Labels; Thiocarbamates | 1995 |
Nitric oxide may upregulate in vivo hepatic protein synthesis during endotoxemia.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Aspartate Aminotransferases; Carbon Radioisotopes; Endotoxins; Leucine; Liver; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Up-Regulation | 1993 |
Induction of nitric oxide synthase regulates atrial natriuretic peptide receptors in vascular smooth muscle cells.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Atrial Natriuretic Factor; Autoradiography; Cells, Cultured; Cross-Linking Reagents; Cyclic GMP; Enzyme Induction; In Vitro Techniques; Interleukin-1; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitrites; Nitroarginine; Nitroprusside; Peptide Fragments; Rabbits; Receptors, Atrial Natriuretic Factor | 1993 |
Adaptation to increased dietary salt intake in the rat. Role of endogenous nitric oxide.
Topics: Adaptation, Physiological; Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Glomerular Filtration Rate; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Renal Circulation; Sodium, Dietary | 1993 |
Cytotoxicity of activated rat macrophages against syngeneic islet cells is arginine-dependent, correlates with citrulline and nitrite concentrations and is identical to lysis by the nitric oxide donor nitroprusside.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Cells, Cultured; Citrulline; Cyclic GMP; Female; Islets of Langerhans; Kinetics; Macrophage Activation; Macrophages; Male; Nitric Oxide; Nitrites; Nitroprusside; omega-N-Methylarginine; Rats; Rats, Wistar; Thionucleotides | 1993 |
Selective inhibition of the inducible nitric oxide synthase by aminoguanidine.
Topics: Amino Acid Oxidoreductases; Animals; Aorta, Thoracic; Arginine; Cells, Cultured; Citrulline; Cyclic GMP; Guanidines; Macrophages; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Sprague-Dawley; Spectrometry, Fluorescence | 1993 |
Endothelin receptor subtype B mediates synthesis of nitric oxide by cultured bovine endothelial cells.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blotting, Northern; Calcium; Calmodulin; Cattle; Cyclic GMP; Endothelins; Endothelium, Vascular; Enzyme Activation; GTP-Binding Proteins; Inosine Triphosphate; Iodine Radioisotopes; Nitrates; Nitric Oxide Synthase; Nitrites; Peptide Fragments; Pertussis Toxin; Receptors, Endothelin; Virulence Factors, Bordetella | 1993 |
IL1 and TNF alpha induce cGMP formation in C6 astrocytoma cells via the nitridergic pathway.
Topics: 1-Methyl-3-isobutylxanthine; Arginine; Astrocytoma; Cyclic GMP; Interleukin-1; Nitrites; omega-N-Methylarginine; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1993 |
Nifedipine inhibits the induction of nitric oxide synthase by bacterial lipopolysaccharide.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Line; Cycloheximide; Dexamethasone; Enzyme Induction; Hemodynamics; Lipopolysaccharides; Lung; Macrophages; Male; Mice; Muscle, Smooth; Nifedipine; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Rats; Rats, Wistar | 1993 |
HIV gp120 glycoprotein stimulates the inducible isoform of no synthase in human cultured astrocytoma cells.
Topics: Amino Acid Oxidoreductases; Antibodies, Monoclonal; Arginine; Astrocytoma; Egtazic Acid; Enzyme Induction; HIV Envelope Protein gp120; HIV-1; Humans; Isoenzymes; Kinetics; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitrites; Recombinant Proteins; Tumor Cells, Cultured | 1993 |
Oxidation of nitric oxide in aqueous solution to nitrite but not nitrate: comparison with enzymatically formed nitric oxide from L-arginine.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Hemeproteins; Humans; Kinetics; Methemoglobin; Myoglobin; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Oxidation-Reduction; Oxyhemoglobins; Solutions | 1993 |
Tetrahydrobiopterin-dependent nitrite oxidation to nitrate in isolated rat hepatocytes.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Biopterins; Cells, Cultured; Cytosol; Humans; Interleukin-1; Kinetics; Lipopolysaccharides; Liver; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1993 |
Role of the nitric oxide synthase pathway in inhibition of growth of interferon-sensitive and interferon-resistant Rickettsia prowazekii strains in L929 cells treated with tumor necrosis factor alpha and gamma interferon.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; In Vitro Techniques; Interferon Type I; Interferon-gamma; L Cells; Mice; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Recombinant Proteins; Rickettsia prowazekii; Tryptophan; Tumor Necrosis Factor-alpha | 1993 |
Nitric oxide production during focal cerebral ischemia in rats.
Topics: Amino Acid Oxidoreductases; Analysis of Variance; Animals; Arginine; Arterial Occlusive Diseases; Brain; Cerebellum; Cerebral Arterial Diseases; Cerebral Cortex; Cyclic GMP; Functional Laterality; Ischemic Attack, Transient; Male; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Rats; Rats, Wistar | 1993 |
Modulation of neuroeffector transmission by endogenous nitric oxide: a role for acetylcholine receptor-activated nitric oxide formation, as indicated by measurements of nitric oxide/nitrite release.
Topics: Acetylcholine; Amino Acid Oxidoreductases; Animals; Arginine; Atropine; Electric Stimulation; Female; Guinea Pigs; Ileum; Iris; Luminescent Measurements; Male; Muscle Contraction; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Rabbits; Receptors, Cholinergic; Substance P; Synaptic Transmission | 1993 |
L-arginine does not prevent the renal effects of endothelin in humans.
Topics: Adult; Arginine; Atrial Natriuretic Factor; Electrolytes; Endothelins; Hemodynamics; Humans; Kidney; Male; Nitrites; Renin | 1995 |
Nitric oxide modulates gamma-interferon-induced MHC class II antigen expression on rat astrocytes.
Topics: Animals; Arginine; Astrocytes; Cyclic AMP; Cyclic GMP; Histocompatibility Antigens Class II; Interferon-gamma; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Nitroprusside; Rats; Rats, Inbred Lew; Rats, Wistar | 1995 |
Effects of prolonged L-arginine administration on blood pressure in patients with essential hypertension (EH).
Topics: Adult; Arginine; Blood Pressure; Cyclic GMP; Fibrinolysis; Heart Rate; Humans; Hypertension; Injections, Intravenous; Male; Middle Aged; Nitrates; Nitrites; Radioimmunoassay | 1995 |
L-arginine may mediate the therapeutic effects of low protein diets.
Topics: Animals; Arginine; Blood Pressure; Body Weight; Diet, Protein-Restricted; Dietary Proteins; Gene Expression; Glomerular Mesangium; Glomerulonephritis; Immune Sera; Kidney Glomerulus; Nitrites; Proteinuria; Proteoglycans; Rats; RNA, Messenger; Thy-1 Antigens; Time Factors; Transforming Growth Factor beta | 1995 |
Relationship between granulocyte macrophage-colony stimulating factor, tumour necrosis factor-alpha and Trypanosoma cruzi infection of murine macrophages.
Topics: Animals; Arginine; Cell Line, Transformed; Cells, Cultured; Granulocyte-Macrophage Colony-Stimulating Factor; Hydrogen Peroxide; Interferon-gamma; Macrophage Activation; Macrophages, Peritoneal; Male; Mice; Mice, Inbred BALB C; Nitric Oxide; Nitrites; omega-N-Methylarginine; Rats; Rats, Inbred F344; Recombinant Proteins; Trypanosoma cruzi; Tumor Necrosis Factor-alpha; Up-Regulation | 1995 |
Plasma nitric oxide end products are increased in the ischemic canine heart.
Topics: Animals; Arginine; Coronary Circulation; Coronary Vessels; Dogs; Hemodynamics; Myocardial Ischemia; Myocardium; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitrites; Oxygen Consumption; Time Factors | 1995 |
The L-arginine:nitric oxide pathway is the major source of plasma nitrite in fasted humans.
Topics: Adult; Arginine; Fasting; Gas Chromatography-Mass Spectrometry; Humans; Male; Nitric Oxide; Nitrites | 1995 |
The effects of administration of nitric oxide inhibitors during small bowel preservation and reperfusion.
Topics: Animals; Arginine; Blood Urea Nitrogen; Glutaminase; Graft Survival; Intestinal Mucosa; Intestine, Small; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; omega-N-Methylarginine; Organ Preservation; Rats; Rats, Inbred Lew; Reperfusion; Reperfusion Injury; Transplantation, Heterotopic | 1994 |
Cyclophosphamide uncovers two separate macrophage subpopulations with opposite immunogenic potential and different patterns of monokine production.
Topics: Animals; Arginine; Cell Division; Cell Line; Cells, Cultured; Cyclophosphamide; Cytokines; Dinoprostone; Hybridomas; Interleukin-6; L Cells; Lipopolysaccharides; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Monokines; Nitrites; omega-N-Methylarginine; Tumor Necrosis Factor-alpha | 1994 |
Inhalation exposure to isobutyl nitrite inhibits macrophage tumoricidal activity and modulates inducible nitric oxide.
Topics: Administration, Inhalation; Animals; Arginine; Cell Adhesion; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Cytotoxicity, Immunologic; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Female; Interferon-gamma; Killer Cells, Natural; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitrites; omega-N-Methylarginine; Sarcoma, Kaposi; Tumor Necrosis Factor-alpha; Vasodilator Agents | 1995 |
Cooling effects on nitric oxide production by rabbit ear and femoral arteries during cholinergic stimulation.
Topics: Animals; Arginine; Arteries; Atropine; Cold Temperature; Ear; Endothelium, Vascular; Female; Femoral Artery; In Vitro Techniques; Male; Methacholine Chloride; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Parasympathetic Nervous System; Rabbits; Regional Blood Flow; Stimulation, Chemical | 1994 |
Photo-induced adequate nitric oxide (PIANO)-mediated relaxation in isolated rabbit corpus cavernosum.
Topics: Animals; Arginine; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Penis; Photolysis; Rabbits; Streptozocin; Ultraviolet Rays | 1994 |
Role of nitric oxide in the peripheral vessels of patients with familial amyloidotic polyneuropathy (FAP) type I.
Topics: Adult; Amyloidosis; Arginine; Blood Vessels; Body Temperature; Female; Humans; Leg; Male; Middle Aged; Muscles; Nitrates; Nitric Oxide; Nitrites; omega-N-Methylarginine; Peripheral Nervous System Diseases; Regional Blood Flow | 1994 |
Generation of nitric oxide inhibits formation of superoxide in macrophages during activation.
Topics: Adenosine Diphosphate; Animals; Arginine; Cells, Cultured; Cytoplasm; Electrophoresis, Polyacrylamide Gel; Interferon-gamma; Lipopolysaccharides; Luminescent Measurements; Macrophage Activation; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Molecular Weight; Mycobacterium bovis; Nitric Oxide; Nitrites; Nitroprusside; omega-N-Methylarginine; Recombinant Proteins; Superoxides; Tetradecanoylphorbol Acetate | 1994 |
Nitric oxide modulates the synthesis of extracellular matrix proteins in cultured rat mesangial cells.
Topics: Animals; Arginine; Cells, Cultured; Collagen; Extracellular Matrix Proteins; Fibronectins; Glomerular Mesangium; Interferon-gamma; Laminin; Lipopolysaccharides; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Rats; Recombinant Proteins | 1995 |
Regulatory role of nitric oxide in the IL-4-induced IgE production by normal human peripheral blood mononuclear cells.
Topics: Arginine; Humans; Immunoglobulin E; In Vitro Techniques; Interleukin-4; Leukocytes, Mononuclear; Molsidomine; Nitric Oxide; Nitrites; omega-N-Methylarginine; Oxidants; Receptors, IgE | 1994 |
L-arginine: nitric oxide pathway in endotoxemia and human septic shock.
Topics: Arginine; Cardiac Output; Creatinine; Endotoxins; Female; Humans; Kidney; Male; Nitrates; Nitric Oxide; Nitrites; Shock, Septic | 1995 |
Roles of gamma interferon and other cytokines in suppression of the spleen cell proliferative response to concanavalin A and toxoplasma antigen during acute toxoplasmosis.
Topics: Acute Disease; Animals; Antibodies, Monoclonal; Antigens, Protozoan; Arginine; Cell Division; Cells, Cultured; Concanavalin A; Cytokines; Female; Immune Tolerance; Interferon-gamma; Interleukin-10; Lymphocytes; Mice; Mice, Inbred CBA; Nitric Oxide; Nitrites; omega-N-Methylarginine; Spleen; Toxoplasmosis, Animal | 1995 |
Modulation of granuloma formation by endogenous nitric oxide.
Topics: Animals; Arginine; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Implants; Granuloma; Inflammation; Macrophages; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Polymers; Prostheses and Implants; Rats; Rats, Wistar; Stereoisomerism | 1994 |
Tumor necrosis factor-alpha regulates in vivo nitric oxide synthesis and induces liver injury during endotoxemia.
Topics: Animals; Arginine; Endotoxins; Female; Lipopolysaccharides; Liver; Mice; Mice, Inbred BALB C; Nitrates; Nitric Oxide; Nitrites; omega-N-Methylarginine; Ornithine Carbamoyltransferase; Propionibacterium acnes; Tumor Necrosis Factor-alpha | 1994 |
Tumor necrosis factor-alpha decreases pulmonary artery endothelial nitrovasodilator via protein kinase C.
Topics: Animals; Arginine; Calcimycin; Cattle; Endothelium, Vascular; Nitrites; Nitro Compounds; Nitroso Compounds; omega-N-Methylarginine; Peroxides; Protein Kinase C; Pulmonary Artery; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Vasodilator Agents | 1994 |
Effects of TNF-alpha on hemodynamic changes and circulating endothelium-derived vasoactive factors in dogs.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arginine; Blood Pressure; Cardiac Output; Dogs; Endothelins; Endothelium, Vascular; Female; Hemodynamics; Humans; Indomethacin; Male; Nitrates; Nitrites; Nitroarginine; Pulmonary Circulation; Reference Values; Time Factors; Tumor Necrosis Factor-alpha; Vascular Resistance | 1994 |
Release of nitric oxide in response to acetylcholine is unaltered in spontaneously hypertensive rats.
Topics: Acetylcholine; Animals; Arginine; Creatinine; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitrites; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1994 |
Hemoglobin augmentation of interleukin-1 beta-induced production of nitric oxide in smooth-muscle cells.
Topics: Animals; Aorta, Thoracic; Arginine; Cell Hypoxia; Cells, Cultured; Cycloheximide; Guanidines; Hemoglobins; Humans; Hydrocortisone; Interleukin-1; Iron; Muscle, Smooth, Vascular; Nitric Oxide; Nitrites; Nitroarginine; Rats | 1994 |
Nitric oxide inhibition normalizes splenocyte interleukin-10 synthesis in murine thermal injury.
Topics: Alcoholism; Animals; Arginine; Burns; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Interferon-gamma; Interleukin-10; Lymphocyte Activation; Male; Mice; Mice, Inbred BALB C; Nitric Oxide; Nitrites; omega-N-Methylarginine; Random Allocation; Spleen | 1994 |
Changes in nitric oxide precursor, L-arginine, and metabolites, nitrate and nitrite, with aging.
Topics: Aging; Animals; Arginine; Fasting; Glomerular Filtration Rate; Male; Nitrates; Nitric Oxide; Nitrites; Proteinuria; Rats; Rats, Sprague-Dawley | 1994 |
Nitric oxide production increases with intraportal islet xenograft transplantation.
Topics: Animals; Arginine; Cell Separation; Humans; Islets of Langerhans; Islets of Langerhans Transplantation; Male; Nitrates; Nitric Oxide; Nitrites; omega-N-Methylarginine; Portal System; Rats; Rats, Inbred F344; Transplantation, Heterologous | 1994 |
Cytokines induce nitric oxide production in mouse osteoblasts.
Topics: 3T3 Cells; Animals; Arginine; Cell Line; Cell Survival; Citrulline; Cycloheximide; Cytokines; Dactinomycin; Dexamethasone; Egtazic Acid; Escherichia coli; Humans; Indomethacin; Interferon-gamma; Interleukin-1; Kinetics; Lipopolysaccharides; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Osteoblasts; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1994 |
Solute transport across the tonoplast of barely mesophyll vacuoles: Mg2+ determines the specificity, and ATP lipophilic amino acids the activity of the amino acid carrier.
Topics: Adenosine Triphosphate; Alanine; Amino Acids; Arginine; Biological Transport; Hordeum; Leucine; Magnesium; Nitrites; Phenylalanine; Potassium; Potassium Channels; Vacuoles | 1994 |
L-arginine-nitric oxide pathway and chronic nephropathy in aged rats.
Topics: Aging; Amino Acids; Animals; Arginine; Blood Urea Nitrogen; Chronic Disease; Creatinine; Dietary Proteins; Dilatation, Pathologic; Guanidines; Kidney Diseases; Kidney Glomerulus; Kidney Tubules; Male; Nitrates; Nitric Oxide; Nitrites; Rats; Rats, Inbred F344; Sclerosis; Specific Pathogen-Free Organisms | 1994 |
Heterogeneous spontaneous and interleukin-4-induced nitric oxide production by human monocytes.
Topics: Arginine; Cells, Cultured; Humans; Interleukin-4; Monocytes; Nitric Oxide; Nitrites; omega-N-Methylarginine; Recombinant Proteins | 1994 |
Role of nitric oxide (EDRF) in radiocontrast acute renal failure in rats.
Topics: Acute Kidney Injury; Animals; Arginine; Blood Pressure; Cyclic GMP; Diatrizoate; Female; Nitrates; Nitric Oxide; Nitrites; Nitroarginine; Rats; Rats, Sprague-Dawley; Sodium; Time Factors | 1994 |
Association between protective efficacy of antibodies to tumor necrosis factor and suppression of nitric oxide production in neonatal rats with fatal infection.
Topics: Animals; Animals, Newborn; Arginine; Bacteremia; Depression, Chemical; Dexamethasone; Isoantibodies; Nitrates; Nitric Oxide; Nitrites; omega-N-Methylarginine; Pseudomonas Infections; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 1993 |
Elevation of plasma nitric oxide end products during focal cerebral ischemia and reperfusion in the rat.
Topics: Animals; Arginine; Blood Pressure; Brain Ischemia; Drug Combinations; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitrites; Rats; Rats, Sprague-Dawley; Reperfusion; Time Factors | 1994 |
Antihistoplasma effect of activated mouse splenic macrophages involves production of reactive nitrogen intermediates.
Topics: Animals; Arginine; Female; Histoplasma; Interferon-gamma; Macrophage Activation; Macrophages; Mice; Mice, Inbred C57BL; Nitrites; omega-N-Methylarginine; Recombinant Proteins; Spleen | 1994 |
Mitogen- and antigen-specific proliferation of T cells in murine toxoplasmosis is inhibited by reactive nitrogen intermediates.
Topics: Animals; Antigens, Protozoan; Arginine; Lymphocyte Activation; Lymphocyte Depletion; Macrophages; Mice; Mice, Inbred BALB C; Mice, Inbred CBA; Nitrites; omega-N-Methylarginine; Spleen; T-Lymphocytes; Toxoplasma; Toxoplasmosis, Animal | 1994 |
Protective role of NO in the regional hemodynamic changes during acute endotoxemia in rats.
Topics: Acute Disease; Animals; Arginine; Blood Pressure; Cardiac Output; Endotoxins; Hemodynamics; Male; Nitrates; Nitric Oxide; Nitrites; Nitroarginine; Rats; Rats, Wistar; Regional Blood Flow; Vascular Resistance | 1994 |
Glomerular thrombosis in pregnancy: role of the L-arginine-nitric oxide pathway.
Topics: Animals; Arginine; Endothelins; Escherichia coli; Female; Glomerular Mesangium; Lipopolysaccharides; Nitrates; Nitric Oxide; Nitrites; Pregnancy; Pregnancy Complications, Cardiovascular; Rats; Rats, Sprague-Dawley; Thrombosis | 1994 |
Interferon-gamma and tumor necrosis factor-alpha exert their antirickettsial effect via induction of synthesis of nitric oxide.
Topics: Animals; Arginine; Cell Division; Cell Line; Cycloheximide; Drug Synergism; Fibroblasts; Interferon-gamma; Kinetics; Nitric Oxide; Nitrites; Nitroprusside; omega-N-Methylarginine; Osmolar Concentration; Rickettsia; Rickettsia Infections; Tumor Necrosis Factor-alpha | 1993 |
Endogenous nitric oxide induced by interleukin-1 beta in rat islets of Langerhans and HIT-T15 cells causes significant DNA damage as measured by the 'comet' assay.
Topics: Animals; Arginine; Cell Line, Transformed; Cricetinae; DNA Damage; Humans; In Vitro Techniques; Interleukin-1; Islets of Langerhans; Kinetics; Nitrates; Nitric Oxide; Nitrites; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Recombinant Proteins | 1993 |
Cytokines regulate L-arginine-dependent cyclic GMP production in rat glial cells.
Topics: Animals; Arginine; Astrocytes; Cells, Cultured; Cyclic GMP; Cytokines; Dexamethasone; Lipopolysaccharides; Neuroglia; Nitrites; Rats; Tumor Cells, Cultured | 1993 |
Inhibition of nitric oxide synthesis is detrimental during endotoxemia.
Topics: Animals; Arginine; Endotoxins; Escherichia coli; Female; Lipopolysaccharides; Lung; Macrophages; Macrophages, Peritoneal; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Peroxidase; Superoxides; Survival Rate | 1994 |
Role of EDRF (nitric oxide) in diabetic renal hyperfiltration.
Topics: Animals; Arginine; Blood Pressure; Diabetes Mellitus, Experimental; Glomerular Filtration Rate; Male; Nitrates; Nitric Oxide; Nitrites; Nitroarginine; Rats; Rats, Sprague-Dawley; Renal Circulation | 1993 |
Arginine uptake and metabolism in cultured murine macrophages.
Topics: Animals; Arginine; Biological Transport; Cells, Cultured; Extracellular Matrix; Intracellular Fluid; Macrophages; Mice; Nitric Oxide; Nitrites | 1993 |
Characterization of the immunosuppressive effects of nitric oxide in graft vs host disease.
Topics: Animals; Arginine; Concanavalin A; Female; Graft vs Host Disease; Immune Tolerance; Lipopolysaccharides; Lymphocyte Activation; Macrophages; Mice; Mice, Inbred Strains; Nitrates; Nitric Oxide; Nitrites; omega-N-Methylarginine; Peritoneal Cavity; Trinitrobenzenes | 1993 |
Plasmodium berghei: is nitric oxide involved in the pathogenesis of mouse cerebral malaria?
Topics: Animals; Arginine; Disease Susceptibility; Malaria, Cerebral; Mice; Mice, Inbred Strains; Nitrates; Nitric Oxide; Nitrites; Nitroarginine; omega-N-Methylarginine; Plasmodium berghei; Plasmodium chabaudi | 1993 |
Rat splenocytes inhibit antigen-specific lymphocyte proliferation through a reactive nitrogen intermediate (RNI)-dependent mechanism and exhibit increased RNI production in response to IFN-gamma.
Topics: Animals; Antigens; Arginine; Cells, Cultured; Dose-Response Relationship, Drug; Female; Interferon-gamma; Lymphocyte Activation; Nitric Oxide; Nitrites; omega-N-Methylarginine; Rats; Rats, Inbred Lew; Spleen; T-Lymphocytes, Regulatory | 1993 |
Nitric oxide mediates cytokine-induced inhibition of insulin secretion by human islets of Langerhans.
Topics: Arginine; Cyclic GMP; Diabetes Mellitus, Type 1; Electron Spin Resonance Spectroscopy; Humans; In Vitro Techniques; Insulin; Insulin Secretion; Interferon-gamma; Interleukin-1; Islets of Langerhans; Nitric Oxide; Nitrites; omega-N-Methylarginine; Recombinant Proteins; Secretory Rate; Tumor Necrosis Factor-alpha | 1993 |
Changes in mechanisms of monocyte/macrophage-mediated cytotoxicity during culture. Reactive oxygen intermediates are involved in monocyte-mediated cytotoxicity, whereas reactive nitrogen intermediates are employed by macrophages in tumor cell killing.
Topics: Arginine; Cells, Cultured; Cytotoxicity, Immunologic; DNA, Neoplasm; Humans; Leukemia, Erythroblastic, Acute; Luminescent Measurements; Macrophages; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Nitric Oxide; Nitrites; omega-N-Methylarginine; Reactive Oxygen Species; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Resistance to nitric oxide in Mycobacterium avium complex and its implication in pathogenesis.
Topics: Animals; Arginine; Drug Resistance, Microbial; Hydrogen-Ion Concentration; Immunity, Cellular; Interferon-gamma; Macrophage Activation; Macrophages, Alveolar; Male; Mycobacterium avium; Nitric Oxide; Nitrites; omega-N-Methylarginine; Phagocytosis; Rats; Rats, Inbred F344; Rats, Wistar; Recombinant Proteins; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate; Tuberculosis | 1993 |
The relationship between L-arginine-dependent nitric oxide synthesis, nitrite release and dinitrosyl-iron complex formation by activated macrophages.
Topics: Animals; Arginine; Ditiocarb; Electron Spin Resonance Spectroscopy; Iron; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Mice, Inbred BALB C; Nitric Oxide; Nitrites; Nitrogen Oxides | 1993 |
Nitric oxide inhibits uterine contractility during pregnancy but not during delivery.
Topics: Animals; Arginine; Delivery, Obstetric; Dose-Response Relationship, Drug; Female; In Vitro Techniques; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitrites; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Uterine Contraction | 1993 |
Induction of NO production by TNF-alpha and lipopolysaccharide in porcine coronary arteries without endothelium.
Topics: Animals; Arginine; Coronary Vessels; Endothelium, Vascular; In Vitro Techniques; Lipopolysaccharides; Nitric Oxide; Nitrites; Serotonin; Swine; Time Factors; Tumor Necrosis Factor-alpha; Vasodilation | 1993 |
Picolinic acid, a catabolite of L-tryptophan, is a costimulus for the induction of reactive nitrogen intermediate production in murine macrophages.
Topics: Animals; Arginine; Cell Line; Drug Synergism; Interferon-gamma; Interleukin-4; Macrophage Activation; Macrophages; Mice; Mice, Inbred C57BL; Nitrites; omega-N-Methylarginine; Picolinic Acids; RNA, Messenger; Tryptophan; Tumor Necrosis Factor-alpha | 1993 |
Increased cerebrospinal fluid concentration of nitrite in Parkinson's disease.
Topics: Aged; Arginine; Female; Humans; Levodopa; Male; Middle Aged; Nitric Oxide; Nitrites; Parkinson Disease; Treatment Outcome | 1995 |
Nramp transfection transfers Ity/Lsh/Bcg-related pleiotropic effects on macrophage activation: influence on oxidative burst and nitric oxide pathways.
Topics: Animals; Arginine; Base Sequence; Carrier Proteins; Cation Transport Proteins; Cell Line; Electron Transport; Free Radical Scavengers; Interferon-gamma; Iron-Binding Proteins; Lipopolysaccharides; Macrophage Activation; Macrophages; Membrane Proteins; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Mutagenesis; Nitric Oxide; Nitrites; Nucleic Acid Hybridization; Reactive Oxygen Species; Respiratory Burst; Transfection | 1995 |
Evidence for cyclooxygenase activation by nitric oxide in astrocytes.
Topics: Animals; Arachidonic Acid; Arginine; Astrocytes; Cells, Cultured; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Activation; Enzyme Inhibitors; Hemoglobins; Lipopolysaccharides; Mice; Mice, Inbred BALB C; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Nitroprusside; Prostaglandin-Endoperoxide Synthases | 1995 |
Acute changes in urinary excretion of nitrite + nitrate do not necessarily predict renal vascular NO production.
Topics: Acetylcholine; Animals; Arginine; Diuretics; Furosemide; Kidney; Male; Nitrates; Nitric Oxide; Nitrites; Nitroprusside; Rats; Rats, Sprague-Dawley; Vascular Resistance; Vasodilator Agents | 1995 |
Effects of nitric oxide on human spermatozoa: evidence that nitric oxide decreases sperm motility and induces sperm toxicity.
Topics: Arginine; Cell Survival; Humans; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroprusside; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Semen; Sperm Motility; Spermatozoa | 1995 |
Excitation of cells in the rostral medial medulla of the rat by the nitric oxide-cyclic guanosine monophosphate messenger system.
Topics: Animals; Arginine; Cyclic GMP; Electrophysiology; Female; Guanosine Monophosphate; Iron; Medulla Oblongata; Methylene Blue; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Rosaniline Dyes; Second Messenger Systems | 1995 |
Interleukin-1 beta and tumor necrosis factor-alpha stimulate the cat-2 gene of the L-arginine transporter in cultured vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Aorta; Arginine; Biological Transport; Carrier Proteins; Cells, Cultured; Gene Expression; Interleukin-1; Kinetics; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitrites; Rats; RNA, Messenger; Transcription, Genetic; Tumor Necrosis Factor-alpha | 1996 |
Ex vivo measurement of brain tissue nitrite and nitrate accurately reflects nitric oxide synthase activity in vivo.
Topics: Animals; Arginine; Brain; Brain Chemistry; Cerebellum; Enzyme Inhibitors; Injections, Intraventricular; Isoenzymes; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrites; Nitroarginine; Rats; Rats, Wistar | 1996 |
NG-monomethyl-L-arginine inhibits the blood flow but not the insulin-like response of forearm muscle to IGF- I: possible role of nitric oxide in muscle protein synthesis.
Topics: Adult; Arginine; Female; Forearm; Humans; Insulin-Like Growth Factor I; Lactates; Lactic Acid; Male; Muscle Proteins; Muscle, Skeletal; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Oxygen Consumption; Phenylalanine; Regional Blood Flow | 1996 |
Interaction between nitric oxide and prostaglandin E2 pathways in pregnant rat uteri.
Topics: Animals; Arginine; Dinoprostone; Enzyme Inhibitors; Female; Indomethacin; Interleukin-1; Labor, Obstetric; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Pregnancy; Pregnancy, Animal; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Uterus | 1996 |
Adrenomedullin increases inducible nitric oxide synthase in rat vascular smooth muscle cells stimulated with interleukin-1.
Topics: Adrenomedullin; Animals; Arginine; Cells, Cultured; Cyclic AMP; Enzyme Inhibitors; Interleukin-1; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Peptides; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 1996 |
Spontaneously increased production of nitric oxide and aberrant expression of the inducible nitric oxide synthase in vivo in the transforming growth factor beta 1 null mouse.
Topics: Amino Acid Sequence; Animals; Arginine; Blotting, Northern; Enzyme Induction; Gene Expression; Genotype; Immunohistochemistry; Isoenzymes; Kidney; Mice; Mice, Knockout; Molecular Sequence Data; Myocardium; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Peptide Fragments; Polymerase Chain Reaction; Reference Values; RNA, Messenger; Transforming Growth Factor beta | 1996 |
Spontaneous rearrangement of aminoalkylisothioureas into mercaptoalkylguanidines, a novel class of nitric oxide synthase inhibitors with selectivity towards the inducible isoform.
Topics: Animals; Aorta; Arginine; Blood Pressure; Cattle; Cell Line; Enzyme Induction; Enzyme Inhibitors; Guanidines; In Vitro Techniques; Isoenzymes; Macrophages; Mice; Muscle Contraction; Nitric Oxide Synthase; Nitrites; Rats; Sulfhydryl Compounds; Thiourea | 1996 |
Increased nitric oxide formation in recurrent thrombotic microangiopathies: a possible mediator of microvascular injury.
Topics: 3,4-Methylenedioxyamphetamine; Acute Disease; Adolescent; Adult; Arginine; Cells, Cultured; Chromatography, High Pressure Liquid; Endothelium, Vascular; Female; Hemolytic-Uremic Syndrome; Humans; Male; Middle Aged; Neutrophils; Nitrates; Nitric Oxide; Nitrites; Purpura, Thrombotic Thrombocytopenic; Recurrence; Superoxides; Thrombosis; Tumor Necrosis Factor-alpha | 1996 |
Protection against hepatic ischemia/reperfusion injury by exogenous L-arginine.
Topics: Animals; Arginine; Citrulline; Cyclic GMP; Liver; Liver Circulation; Male; Nitrates; Nitric Oxide; Nitrites; Rats; Rats, Wistar; Regional Blood Flow; Reperfusion; Reperfusion Injury | 1996 |
Suppression of cytochrome P450- and UDP glucuronosyl transferase-dependent enzyme activities by proinflammatory cytokines and possible role of nitric oxide in primary cultures of pig hepatocytes.
Topics: Acute-Phase Reaction; Animals; Arginine; Cells, Cultured; Culture Media; Cytochrome P-450 Enzyme System; Cytokines; Gene Expression; Glucuronosyltransferase; Humans; Interleukin-1; Interleukin-6; Liver; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitrites; Swine; Tumor Necrosis Factor-alpha | 1996 |
Role of tetrahydrobiopterin availability in the regulation of nitric-oxide synthase expression in human mesangial cells.
Topics: Arginine; Biopterins; Cells, Cultured; Enzyme Induction; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Glomerular Mesangium; Humans; Interleukin-1; Kinetics; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitrites; Nitroprusside; Pteridines; Pterins; Recombinant Proteins; RNA, Messenger; Sugar Acids; Transcription, Genetic; Tumor Necrosis Factor-alpha | 1996 |
Relevance of the arginine transport activity to the nitric oxide synthesis in mouse peritoneal macrophages stimulated with bacterial lipopolysaccharide.
Topics: Amino Acid Transport Systems; Animals; Arginine; Biological Transport; Carrier Proteins; Cells, Cultured; Culture Media; Extracellular Space; Female; Gene Expression Regulation; Intracellular Fluid; Lipopolysaccharides; Lysine; Macrophages, Peritoneal; Mice; Nitric Oxide; Nitrites | 1996 |
Nitric oxide in streptozotocin-induced diabetes mellitus in rats.
Topics: Alloxan; Animals; Arginine; Creatine; Diabetes Mellitus, Experimental; Metabolic Clearance Rate; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Rats; Rats, Wistar | 1996 |
Regulation of bovine endothelial constitutive nitric oxide synthase by oxygen.
Topics: Aerobiosis; Animals; Aorta; Arginine; Blotting, Northern; Cattle; Cell Hypoxia; Cells, Cultured; DNA, Complementary; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Kinetics; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitrites; Oxygen; Pulmonary Artery; RNA, Messenger; Time Factors; Transcription, Genetic | 1995 |
L-arginine depletion inhibits glomerular nitric oxide synthesis and exacerbates rat nephrotoxic nephritis.
Topics: Animals; Arginase; Arginine; Cell Survival; Globulins; Glomerulonephritis; Kidney Glomerulus; Macrophages, Peritoneal; Male; Nitric Oxide; Nitrites; Proteinuria; Rats; Rats, Inbred Lew; Time Factors | 1996 |
Oxidative denitrification of N omega-hydroxy-L-arginine by the superoxide radical anion.
Topics: Arginine; Hydrogen-Ion Concentration; Models, Chemical; Nitric Oxide; Nitrites; Oxidation-Reduction; Superoxides | 1996 |
Ginsenosides stimulate endogenous production of nitric oxide in rat kidney.
Topics: Animals; Arginine; Cyclic GMP; Enzyme Inhibitors; Evaluation Studies as Topic; Ginsenosides; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Panax; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Saponins; Stimulation, Chemical | 1996 |
Peroxynitrite formation from activated human leukocytes.
Topics: Animals; Arginine; Enzyme Inhibitors; Humans; Luminescent Measurements; Macrophages, Alveolar; Neutrophils; Nitrates; Nitrites; Nitrophenols; omega-N-Methylarginine; Peroxidase; Phenylacetates; Rats; Superoxides; Tetradecanoylphorbol Acetate | 1996 |
Effect of multiple cytokines plus bacterial endotoxin on glucose and nitric oxide production by cultured hepatocytes.
Topics: Animals; Arginine; Cells, Cultured; Cytokines; Drug Interactions; Enzyme Inhibitors; Glucose; Lipopolysaccharides; Liver; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Shock, Septic; Time Factors | 1996 |
Urinary NO3- excretion as an indicator of nitric oxide formation in vivo during oral administration of L-arginine or L-name in rats.
Topics: Animals; Arginine; Creatinine; Cyclic GMP; Enzyme Inhibitors; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Rats; Rats, Wistar; Time Factors; Urination | 1996 |
Nitric oxide exposure and sulfhydryl modulation alter L-arginine transport in cultured pulmonary artery endothelial cells.
Topics: Acetylcysteine; Acrolein; Animals; Arginine; Biological Transport; Cells, Cultured; Dithiothreitol; Endothelium, Vascular; Ethylmaleimide; L-Lactate Dehydrogenase; Lipid Peroxidation; Nitrates; Nitric Oxide; Nitrites; Penicillamine; Pulmonary Artery; S-Nitroso-N-Acetylpenicillamine; Sulfhydryl Compounds; Swine | 1996 |
NG-nitro-L-arginine methyl ester causes glomerular nitrite production in long-term incubations.
Topics: Animals; Arginine; Enzyme Inhibitors; Female; In Vitro Techniques; Kidney Glomerulus; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitrites; Rats; Rats, Wistar | 1996 |
Temporal relationships between levels of circulating NO derivatives, vascular NO production and hyporeactivity to noradrenaline induced by endotoxin in rats.
Topics: Animals; Arginine; Blood Pressure; Cyclic GMP; In Vitro Techniques; Lipopolysaccharides; Male; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Norepinephrine; Rats; Rats, Wistar; Shock, Septic; Time Factors | 1995 |
Mechanism of hypertension induced by chronic inhibition of nitric oxide in rats.
Topics: Animals; Arginine; Blood Pressure; Catecholamines; Enzyme Inhibitors; Heart Rate; Hemodynamics; Hypertension; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Rats; Rats, Wistar; Time Factors | 1995 |
Attenuated Salmonella vaccine-induced suppression of murine spleen cell responses to mitogen is mediated by macrophage nitric oxide: quantitative aspects.
Topics: Animals; Arginine; Bacterial Vaccines; Concanavalin A; Enzyme Inhibitors; Female; Immunosuppression Therapy; Interferon-gamma; Lymphocyte Activation; Mice; Mice, Inbred C3H; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Salmonella typhimurium; Spleen; Vaccines, Attenuated | 1996 |
Human monocytes induce a carcinoma cell line to secrete high amounts of nitric oxide.
Topics: Arginine; Carcinoma, Transitional Cell; Coculture Techniques; Drug Combinations; Humans; Interleukin-1; Kidney Medulla; Leucine; Macrophage Activation; Monocytes; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Solubility; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Urinary Bladder Neoplasms | 1996 |
Dengue virus-induced cytotoxin releases nitrite by spleen cells.
Topics: Animals; Arginase; Arginine; Calcium; Cell Culture Techniques; Cytokines; Cytotoxicity, Immunologic; Cytotoxins; Dengue Virus; Dose-Response Relationship, Immunologic; Immune Sera; Mice; Mice, Inbred Strains; Nitric Oxide; Nitrites; omega-N-Methylarginine; Proteins; Spleen; Sulfates; Zinc Compounds; Zinc Sulfate | 1996 |
Bacterial superantigen-induced human lymphocyte responses are nitric oxide dependent and mediated by IL-12 and IFN-gamma.
Topics: Animals; Antibodies, Monoclonal; Arginine; Bacterial Proteins; Base Sequence; DNA Primers; Enzyme Inhibitors; Exotoxins; Humans; In Vitro Techniques; Interferon-gamma; Interleukin-12; Kinetics; Lymphocyte Activation; Lymphocytes; Lymphotoxin-alpha; Membrane Proteins; Mice; Molecular Sequence Data; Neutralization Tests; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Superantigens | 1996 |
Glucocorticoids regulate inducible nitric oxide synthase by inhibiting tetrahydrobiopterin synthesis and L-arginine transport.
Topics: Animals; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Biological Transport; Biopterins; Cells, Cultured; Cytokines; Dexamethasone; Gene Expression Regulation, Enzymologic; Glucocorticoids; GTP Cyclohydrolase; Interferon-gamma; Interleukin-1; Male; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Sprague-Dawley; Recombinant Proteins | 1996 |
L-arginine infusion reduces preterm uterine contractions.
Topics: Arginine; Female; Human Growth Hormone; Humans; Infusions, Intravenous; Nitrites; Obstetric Labor, Premature; Pilot Projects; Pregnancy; Pregnancy Trimester, Third; Ritodrine; Sodium Chloride; Tocolytic Agents; Uterine Contraction | 1996 |
Role of nitric oxide in the hypoxemia-induced renal dysfunction of the newborn rabbit.
Topics: Animals; Animals, Newborn; Arginine; Blood Gas Analysis; Blood Pressure; Female; Hypoxia; Kidney; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitrites; Rabbits; Renal Circulation | 1996 |
Hyporeactivity of mesenteric vascular bed in endotoxin-treated rats.
Topics: Animals; Arginine; Enzyme Inhibitors; Lipopolysaccharides; Male; Mesentery; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitrites; Norepinephrine; Rats; Rats, Wistar; Vascular Resistance | 1996 |
Whole body nitric oxide synthesis in healthy men determined from [15N] arginine-to-[15N]citrulline labeling.
Topics: Adult; Arginine; Citrulline; Eating; Fasting; Humans; Isotope Labeling; Male; Models, Biological; Nitrates; Nitric Oxide; Nitrites; Nitrogen Isotopes; Time Factors | 1996 |
Nitric oxide in ischaemic acute renal failure of streptozotocin diabetic rats.
Topics: Acute Kidney Injury; Analysis of Variance; Animals; Arginine; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Ischemia; Nephrectomy; Nitrates; Nitric Oxide; Nitrites; Nitroarginine; Rats; Rats, Wistar; Reference Values; Renal Artery; Renal Circulation; Sodium | 1996 |
Role of endothelium-related mechanisms in the pathophysiology of renal ischemia/reperfusion in normal rabbits.
Topics: Animals; Arginine; Endothelium, Vascular; Hemodynamics; Ischemia; Kidney; Male; Neutrophils; Nitric Oxide; Nitrites; Peroxidase; Rabbits; Reference Values; Renal Circulation; Reperfusion; Time Factors; Vasodilation | 1996 |
Nitric oxide in brain death related cardiovascular dysfunction.
Topics: Animals; Arginine; Brain Death; Disease Models, Animal; Dogs; Fourier Analysis; Hemodynamics; Male; Nitric Oxide; Nitrites; Time Factors | 1996 |
Evidence for inducible nitric oxide synthase in spontaneously hypertensive rats.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Animals; Aorta, Thoracic; Arginine; Blood Pressure; Cyclic GMP; Enzyme Induction; Guanidines; In Vitro Techniques; Isoenzymes; Lipopolysaccharides; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitrites; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tumor Necrosis Factor-alpha | 1996 |
Effect of L-arginine on myoglobin-induced acute renal failure in the rabbit.
Topics: Acute Kidney Injury; Animals; Arginine; Creatinine; Cyclic GMP; Male; Myoglobin; Nitrates; Nitrites; Rabbits; Renal Circulation; Vascular Resistance | 1996 |
Inhibition of the catalytic activity of alcohol dehydrogenase by nitric oxide is associated with S nitrosylation and the release of zinc.
Topics: Alcohol Dehydrogenase; Animals; Arginine; Cells, Cultured; Chlorides; Cytokines; Cytosol; Dithiothreitol; Hemoglobins; Horses; Humans; Interferon-gamma; Kinetics; Liver; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Nitroso Compounds; Penicillamine; Rats; Rats, Sprague-Dawley; Recombinant Proteins; S-Nitroso-N-Acetylpenicillamine; Tumor Necrosis Factor-alpha; Zinc Compounds | 1996 |
Nitrite generation in interleukin-4-treated human macrophage cultures does not involve the nitric oxide synthase pathway.
Topics: Amino Acids; Animals; Arginine; Biopterins; Cells, Cultured; Culture Media; Female; Humans; Interferon-gamma; Interleukin-4; Macrophages; Male; Muscle, Smooth, Vascular; Neopterin; Nitrates; Nitric Oxide Synthase; Nitrites; Oxidation-Reduction; Rats; Recombinant Proteins | 1997 |
Inducible nitric oxide synthase in rat brown adipocytes: implications for blood flow to brown adipose tissue.
Topics: Adipocytes; Adipose Tissue, Brown; Animals; Arginine; Cells, Cultured; Citrulline; Dactinomycin; Enzyme Induction; Enzyme Inhibitors; Kinetics; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitrites; Norepinephrine; Rats; Rats, Sprague-Dawley; Regional Blood Flow | 1997 |
Oxidation of N(G)-hydroxyl-L-arginine to nitric oxide mediated by respiratory burst: an alternative pathway to NO synthesis.
Topics: Animals; Arginine; Cells, Cultured; Humans; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Oxidation-Reduction; Phagocytes; Respiratory Burst; Superoxides | 1997 |
Nitric oxide (NO) modulates the neurogenic control of blood pressure in rats with chronic renal failure (CRF).
Topics: Angiotensin II; Animals; Aorta; Arginine; Blood Pressure; Brain; Creatinine; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Hypertension; Hypothalamus; Kidney Failure, Chronic; Locus Coeruleus; Male; Medulla Oblongata; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Norepinephrine; Paraventricular Hypothalamic Nucleus; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sympathetic Nervous System; Synaptic Transmission; Transcription, Genetic | 1997 |
Simultaneous measurement of nitrite and nitrate levels as indices of nitric oxide release in the cerebellum of conscious rats.
Topics: Animals; Arginine; Calcium; Cerebellum; Enzyme Inhibitors; Extracellular Space; Glutamic Acid; Male; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Wistar | 1997 |
Possible mechanism of nitric oxide production from N(G)-hydroxy-L-arginine or hydroxylamine by superoxide ion.
Topics: Animals; Arginine; Cell Line; Hydrogen-Ion Concentration; Hydroxylamine; Hydroxylamines; In Vitro Techniques; Macrophage Activation; Male; Mice; Microsomes, Liver; Nitrates; Nitric Oxide; Nitrites; Oxidation-Reduction; Rats; Rats, Wistar; Solutions; Superoxides; Water | 1996 |
Evidence that nitric oxide inhibits steroidogenesis in cultured rat granulosa cells.
Topics: Animals; Arginine; Cells, Cultured; Coculture Techniques; Dose-Response Relationship, Drug; Female; Granulosa Cells; Guanidines; Macrophages; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroprusside; omega-N-Methylarginine; Penicillamine; Progesterone; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents | 1997 |
L-Arginine and allopurinol protect against cyclosporine nephrotoxicity.
Topics: Allopurinol; Animals; Arginine; Cyclosporine; Enzyme Inhibitors; Glomerular Filtration Rate; Inulin; Kidney Diseases; Male; Nitrates; Nitric Oxide; Nitrites; Potassium; Rats; Xanthine Oxidase | 1997 |
Activation of the L-arginine nitric oxide pathway in severe sepsis.
Topics: Adolescent; Arginine; Biomarkers; Child; Child, Preschool; Female; Humans; Infant; Male; Multiple Organ Failure; Nitrates; Nitrites; Nitrogen Oxides; Shock, Septic; Systemic Inflammatory Response Syndrome | 1997 |
Endogenous nitric oxide limits cytokine-induced damage of murine lung epithelial cells.
Topics: Animals; Arginine; Cytokines; Drug Combinations; Enzyme Inhibitors; Epithelium; Ethidium; Glutathione; Guanylate Cyclase; Interferon-gamma; Interleukin-1; Lung; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroso Compounds; Oxadiazoles; Quinoxalines; S-Nitrosoglutathione; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1997 |
A novel nonenzymatic pathway for the generation of nitric oxide by the reaction of hydrogen peroxide and D- or L-arginine.
Topics: Amino Acids; Arginine; Hydrogen Peroxide; Luminescent Measurements; Nitrates; Nitric Oxide; Nitrites | 1997 |
Improvement of cardiac output and liver blood flow and reduction of pulmonary vascular resistance by intravenous infusion of L-arginine during the early reperfusion period in pig liver transplantation.
Topics: Animals; Arginine; Blood Urea Nitrogen; Cardiac Output; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Infusions, Intravenous; Liver; Liver Circulation; Liver Transplantation; Male; Nitrates; Nitrites; Oxygen; Reperfusion Injury; Swine; Vascular Resistance | 1997 |
Amino acid profile and nitric oxide pathway in patients on continuous ambulatory peritoneal dialysis: L-arginine depletion in acute peritonitis.
Topics: Acute Disease; Adolescent; Adult; Aged; Amino Acids; Analysis of Variance; Arginine; Child; Dialysis Solutions; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Nitric Oxide; Nitrites; Peritoneal Dialysis, Continuous Ambulatory; Peritonitis | 1997 |
Suppression of intestinal and hepatic cytochrome P4503A in murine Toxoplasma infection. Effects of N-acetylcysteine and N(G)-monomethyl-L-arginine on the hepatic suppression.
Topics: Acetylcysteine; Animals; Antibodies, Monoclonal; Arginine; Aryl Hydrocarbon Hydroxylases; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Erythromycin; Interferon-gamma; Intestinal Mucosa; Jejunum; Macrophages, Peritoneal; Male; Mice; Mice, Inbred CBA; Microsomes; Microsomes, Liver; Nitrites; Oxidoreductases, N-Demethylating; Toxoplasmosis, Animal | 1996 |
'Locked-on' and 'locked-off' signal transduction mutations in the periplasmic domain of the Escherichia coli NarQ and NarX sensors affect nitrate- and nitrite-dependent regulation by NarL and NarP.
Topics: Alanine; Amino Acid Sequence; Arginine; Bacterial Proteins; Binding Sites; Cytoplasm; DNA-Binding Proteins; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Lac Operon; Membrane Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Nitrate Reductase; Nitrate Reductases; Nitrates; Nitrites; Phosphoproteins; Protein Kinases; Signal Transduction | 1997 |
Two pathways of nitric oxide production through glutamate receptors in the rat cerebellum in vivo.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arginine; Calcium; Cerebellum; Cycloleucine; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; Male; N-Methylaspartate; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Wistar; Receptors, Glutamate | 1997 |
Role of exogenous L-arginine in hepatic ischemia-reperfusion injury.
Topics: Animals; Arginine; Aspartate Aminotransferases; Blood Pressure; Citrulline; Cyclic GMP; Female; Hemodynamics; Liver; Male; Nitrates; Nitric Oxide; Nitrites; Rats; Rats, Wistar; Reperfusion Injury; Swine; Time Factors | 1997 |
Long-term dietary supplementation with L-arginine prevents age-related reduction in renal function.
Topics: Aging; Animals; Arginine; Body Weight; Cell Movement; Diet; Hemodynamics; Kidney; Kidney Glomerulus; Macrophages; Male; Nitrates; Nitrites; Organ Size; Proteinuria; Rats; Renal Circulation; Sclerosis; Time Factors | 1997 |
Nitric oxide inhibits IgE-mediated degranulation of mast cells and is the principal intermediate in IFN-gamma-induced suppression of exocytosis.
Topics: Animals; Arginine; Cell Degranulation; Cell Separation; Exocytosis; Female; Gene Deletion; Glutathione; Immunoglobulin E; Immunosuppressive Agents; Interferon gamma Receptor; Interferon-gamma; Mast Cells; Mice; Mice, Knockout; Nitric Oxide; Nitrites; Nitroprusside; Nitroso Compounds; omega-N-Methylarginine; Receptors, Interferon; S-Nitrosoglutathione | 1997 |
Post-transcriptional regulation of inducible nitric oxide synthase mRNA in murine macrophages by doxycycline and chemically modified tetracyclines.
Topics: Animals; Arginine; Citrulline; Doxycycline; Hydrocortisone; Macrophages; Mice; Minocycline; Molecular Structure; Nitric Oxide Synthase; Nitrites; RNA Processing, Post-Transcriptional; RNA, Messenger; Tetracyclines | 1997 |
Identification of nitric oxide synthase in human and bovine oviduct.
Topics: Animals; Arginine; Cattle; Cells, Cultured; Citrulline; Epithelial Cells; Epithelium; Fallopian Tubes; Female; Humans; In Vitro Techniques; NADPH Dehydrogenase; Nitrates; Nitric Oxide Synthase; Nitrites | 1996 |
Selective inhibition of inducible nitric oxide synthase inhibits tumor growth in vivo: studies with 1400W, a novel inhibitor.
Topics: Adenocarcinoma; Amidines; Animals; Arginine; Benzylamines; Colonic Neoplasms; Enzyme Inhibitors; Hematopoietic Stem Cells; Humans; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Nitrates; Nitric Oxide Synthase; Nitrites; Transplantation, Heterologous | 1997 |
High glucose inhibits nitric oxide production in cultured rat mesangial cells.
Topics: Amino Acids; Animals; Arginine; Cells, Cultured; Diabetic Nephropathies; Glomerular Mesangium; Glucose; Humans; Hyperglycemia; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats | 1997 |
Nutritional regulation of plasma tumor necrosis factor-alpha and plasma and urinary nitrite/nitrate responses to endotoxin in cattle.
Topics: Animals; Arginine; Blood Urea Nitrogen; Cattle; Dietary Proteins; Escherichia coli; Female; Lipopolysaccharides; Liver; Nitrates; Nitric Oxide Synthase; Nitrites; Tumor Necrosis Factor-alpha | 1997 |
Protection of perfused lung from oxidant injury by inhibitors of anion exchange.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Antiporters; Arginine; Blotting, Western; Buffers; Dipyridamole; Extracellular Space; Hypertension, Pulmonary; Immunohistochemistry; In Vitro Techniques; Lung; Nitrites; Oxidants; Oxygen; Perfusion; Pulmonary Edema; Rabbits; Superoxides | 1997 |
Differential effect of L-NAME and S-methyl-isothiourea on leukocyte emigration in carrageenin-soaked sponge implants in rat.
Topics: Animals; Arginine; Capillary Permeability; Carrageenan; Cell Movement; Enzyme Inhibitors; Epoprostenol; Inflammation; Isothiuronium; Leukocytes; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 1997 |
Ketamine inhibits nitric oxide synthase in lipopolysaccharide-treated rat alveolar macrophages.
Topics: Analysis of Variance; Anesthetics, Dissociative; Animals; Arginine; Blotting, Western; Cell Respiration; Cell Survival; Cells, Cultured; Citrulline; Culture Media; Dose-Response Relationship, Drug; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation, Enzymologic; Ketamine; Lipopolysaccharides; Macrophages, Alveolar; Male; Nitric Oxide Synthase; Nitrites; Radiopharmaceuticals; Rats; Rats, Inbred WKY; Tritium; Tumor Necrosis Factor-alpha | 1997 |
Vascular endothelial cells generate peroxynitrite in response to carbon monoxide exposure.
Topics: Animals; Arginine; Carbon Monoxide; Cattle; Cell Survival; Cells, Cultured; Chromium; Endothelium, Vascular; Nitrates; Nitric Oxide Synthase; Nitrites; Oxidants; Oxidation-Reduction; Oxygen Consumption; Sulfhydryl Compounds; Tetrazolium Salts; Thiazoles; Tyrosine | 1997 |
Tetrahydrobiopterin regulates cyclic GMP-dependent electrogenic Cl- secretion in mouse ileum in vitro.
Topics: Animals; Antioxidants; Arginine; Biopterins; Carbachol; Chloride Channels; Cholinergic Agonists; Cyclic GMP; Ileum; In Vitro Techniques; Intestinal Mucosa; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Muscle, Smooth; Nitric Oxide; Nitrites; Time Factors | 1997 |
Effects of NO synthase inhibitors, arginine-deficient diet, and amiloride in pregnant rats.
Topics: Abnormalities, Drug-Induced; Amiloride; Analysis of Variance; Animals; Arginine; Female; Fetal Death; Fetal Growth Retardation; Gestational Age; Guanidines; Limb Deformities, Congenital; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrites; Ornithine; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 1997 |
Arginine deficiency in bile duct-ligated rats after surgery: the role of plasma arginase and gut endotoxin restriction.
Topics: Animals; Arginase; Arginine; Cholestasis; Cholestyramine Resin; Common Bile Duct; Endotoxemia; Hematocrit; Kidney; Liver; Male; Nitrates; Nitrites; Ornithine; Postoperative Complications; Rats; Rats, Wistar; Regression Analysis; Urea | 1997 |
Nitric oxide synthase activity and mRNA expression in chicken macrophages.
Topics: Animals; Arginine; Blotting, Northern; Cell Line; Cell Line, Transformed; Chickens; Dose-Response Relationship, Drug; Lipopolysaccharides; Lymphokines; Macrophages; Nitric Oxide Synthase; Nitrites; RNA, Messenger; Time Factors | 1997 |
Decreased L-arginine during peritonitis in ESRD patients on peritoneal dialysis.
Topics: Acute Disease; Adolescent; Adult; Aged; Amino Acids; Arginine; Child; Dialysis Solutions; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Nitric Oxide; Nitrites; Peritoneal Dialysis; Peritonitis | 1997 |
Effect of long-term oral L-arginine on the nitric oxide synthase pathway in the urine from patients with interstitial cystitis.
Topics: Administration, Oral; Arginine; Cyclic GMP; Cystitis, Interstitial; Female; Humans; Nitrates; Nitric Oxide Synthase; Nitrites; Time Factors | 1997 |
Nitric oxide accelerates the onset and increases the severity of experimental autoimmune uveoretinitis through an IFN-gamma-dependent mechanism.
Topics: Animals; Arginine; Autoimmune Diseases; Cytokines; Immunohistochemistry; Interferon-gamma; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Inbred Lew; Retinitis; RNA, Messenger; Uveitis | 1997 |
Endotoxin impairs agonist-induced calcium mobilization in rat mesangial cells.
Topics: Animals; Arginine; Bradykinin; Cell Survival; Cells, Cultured; Culture Media, Conditioned; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Endotoxins; Enzyme Inhibitors; Escherichia coli; Glomerular Mesangium; Indomethacin; Lipopolysaccharides; Meclofenamic Acid; Microspectrophotometry; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Thrombin | 1997 |
Superoxide generation by renal proximal tubule nitric oxide synthase.
Topics: Analysis of Variance; Animals; Arginine; In Vitro Techniques; Kidney Tubules, Proximal; L-Lactate Dehydrogenase; Lipid A; Lipid Peroxidation; Male; Malondialdehyde; Nitrates; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Stereoisomerism; Superoxides | 1997 |
Sphingomyelinase and ceramide stimulate the expression of inducible nitric-oxide synthase in rat primary astrocytes.
Topics: Acetylcysteine; Alkyl and Aryl Transferases; Animals; Arginine; Astrocytes; Brain; Cells, Cultured; Ceramides; Cytokines; Drug Interactions; Enzyme Induction; Flavonoids; Lipopolysaccharides; Mitogen-Activated Protein Kinase Kinases; Neuroglia; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Protein Kinase Inhibitors; Pyrrolidines; Rats; Signal Transduction; Sphingomyelin Phosphodiesterase; Thiocarbamates | 1998 |
Inducible nitric oxide synthase augments injury elicited by oxidative stress in rat cardiac myocytes.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Animals, Newborn; Arginine; Cells, Cultured; Cyclic GMP; Enzyme Induction; Glutathione Peroxidase; Heart; Heart Injuries; Kinetics; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Oligonucleotides, Antisense; Oxidative Stress; Penicillamine; Rats; S-Nitroso-N-Acetylpenicillamine | 1998 |
Evidence suggesting that nitric oxide mediates iron-induced toxicity in cultured proximal tubule cells.
Topics: Animals; Arginine; Cell Survival; Cells, Cultured; Enzyme Induction; Enzyme Inhibitors; Guanidines; Iron; Kidney Tubules, Proximal; L-Lactate Dehydrogenase; Lipid Peroxidation; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroprusside; Rats; Rats, Wistar | 1998 |
Effect of the nitric oxide level in the medial preoptic area on male copulatory behavior in rats.
Topics: Animals; Arginine; Copulation; Ejaculation; Female; Infusions, Parenteral; Male; Microdialysis; Nitrates; Nitric Oxide; Nitrites; omega-N-Methylarginine; Posture; Preoptic Area; Rats; Rats, Wistar; Time Factors | 1998 |
The cytotoxicity of nitroxyl: possible implications for the pathophysiological role of NO.
Topics: Animals; Arginine; Buthionine Sulfoximine; Cell Death; Cell Line; Cricetinae; Cricetulus; Cyclic N-Oxides; DNA Damage; Ferricyanides; Fibroblasts; Free Radical Scavengers; Free Radicals; Glutathione; Lung; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitrogen Oxides; Spin Labels | 1998 |
L-arginine suppresses lipopolysaccharide-induced expression of RANTES in glomeruli.
Topics: Animals; Antibodies, Monoclonal; Arginine; Blotting, Northern; Chemokine CCL5; Chemotaxis; Enzyme Inhibitors; Immunohistochemistry; Kidney Glomerulus; Lipopolysaccharides; Macrophages; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Rats; Rats, Wistar | 1998 |
Arginase activity is modulated by IL-4 and HOArg in nephritic glomeruli and mesangial cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginase; Arginine; Cholera Toxin; Cyclic AMP; Glomerular Mesangium; Interleukin-1; Interleukin-4; Isoenzymes; Kidney Glomerulus; Macrophages, Peritoneal; Male; Nephritis; Nitrites; Rats; Rats, Inbred Lew | 1998 |
Upregulation of renal and vascular nitric oxide synthase in young spontaneously hypertensive rats.
Topics: Age Factors; Animals; Aorta, Thoracic; Arginine; Blotting, Western; Body Weight; Creatinine; Data Interpretation, Statistical; Endothelium, Vascular; Hematocrit; Hypertension; In Vitro Techniques; Kidney; Luminescent Measurements; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Up-Regulation | 1998 |
Paradoxical changes in organ blood flow after arginase infusion in the non-stressed rat.
Topics: Animals; Arginase; Arginine; Coronary Circulation; Hemodynamics; Kidney; Liver Circulation; Male; Nitrates; Nitrites; Rats; Rats, Wistar; Regional Blood Flow; Spleen; Vascular Resistance | 1998 |
Role of endothelin and nitric oxide imbalance in the pathogenesis of hypoxia-induced arterial hypertension.
Topics: Acetamides; Animals; Arginine; Blood Pressure; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelins; Hypertension, Renal; Hypoxia; Kidney; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B; Renal Circulation | 1998 |
The involvement of nitric oxide in stress-impaired testicular steroidogenesis.
Topics: Animals; Arginine; Enzyme Inhibitors; Immobilization; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Wistar; Steroids; Stress, Psychological; Testis; Testosterone | 1998 |
Substrate specificity of NO synthases: detailed comparison of L-arginine, homo-L-arginine, their N omega-hydroxy derivatives, and N omega-hydroxynor-L-arginine.
Topics: Animals; Arginine; Catalysis; Cattle; Citrulline; Homoarginine; Kinetics; NADP; Nitric Oxide Synthase; Nitrites; Oxidation-Reduction; Oxygen; Substrate Specificity | 1998 |
Factors contributing to differences in the regulation of cGMP in isolated porcine pulmonary vessels.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Blotting, Western; Carbon Radioisotopes; Citrulline; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Female; Guanylate Cyclase; Male; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Pulmonary Veins; Purinones; Swine | 1998 |
Stimulation of nitric oxide production in macrophages by Babesia bovis.
Topics: Animals; Arginine; Babesia bovis; Cattle; Cell Line; Cells, Cultured; Culture Media, Conditioned; Dose-Response Relationship, Drug; Gene Expression Regulation; Interferon-gamma; Macrophages; Mycoplasma; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; RNA, Messenger; T-Lymphocytes, Helper-Inducer | 1998 |
Importance of glutamine metabolism in murine macrophages and human monocytes to L-arginine biosynthesis and rates of nitrite or urea production.
Topics: Animals; Arginine; Diazooxonorleucine; Enzyme Inhibitors; Glutaminase; Glutamine; Humans; Lipopolysaccharides; Macrophage Activation; Macrophages, Peritoneal; Male; Mice; Mice, Inbred Strains; Monocytes; Mycobacterium bovis; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Urea | 1998 |
Nitric oxide protection of rat liver from lipid peroxidation, collagen accumulation, and liver damage induced by carbon tetrachloride.
Topics: Animals; Arginine; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Collagen; Drug Interactions; Enzyme Inhibitors; Guanidines; Lipid Peroxidation; Liver; Liver Diseases; Liver Glycogen; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Wistar | 1998 |
The nitric oxide system and cortisol-induced hypertension in humans.
Topics: Arginine; Humans; Hydrocortisone; Hypertension; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites | 1998 |
Role of nitric oxide in cyclosporine A-induced hypertension.
Topics: Animals; Aorta; Arginine; Blood Pressure; Bosentan; Cyclic GMP; Cyclosporine; Endothelin Receptor Antagonists; Enzyme Inhibitors; Hypertension; Immunosuppressive Agents; Male; Nitrates; Nitrites; Olive Oil; Penicillamine; Peptides, Cyclic; Plant Oils; Rats; Rats, Sprague-Dawley; Sulfonamides; Vasoconstriction | 1998 |
Effect of exogenous L-arginine for hepatic ischemia-reperfusion injury in an isolated rat liver in vitro.
Topics: Animals; Arginine; In Vitro Techniques; Liver; Male; Nitrates; Nitrites; Organ Preservation; Rats; Rats, Wistar; Reperfusion; Reperfusion Injury; Time Factors | 1998 |
Impairment of nitric oxide-mediated relaxations in anaesthetized autoperfused streptozotocin-induced diabetic rats.
Topics: Acetylcholine; Anesthesia; Animals; Arginine; Blood Glucose; Blood Pressure; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Enzyme Inhibitors; Free Radical Scavengers; Glycated Hemoglobin; Heart Rate; Hindlimb; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitrites; Perfusion; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Vasodilation; Vasodilator Agents | 1998 |
Effect of inhibition of nitric oxide synthase on Pseudomonas aeruginosa infection of respiratory mucosa in vitro.
Topics: Arginine; Bacterial Adhesion; Enzyme Inhibitors; Gene Expression; Humans; Microscopy, Electron, Scanning; Mucous Membrane; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; omega-N-Methylarginine; Organ Culture Techniques; Pseudomonas aeruginosa; Respiratory System; RNA, Messenger | 1998 |
Nitrogen oxides and hydroxyguanidines: formation of donors of nitric and nitrous oxides and possible relevance to nitrous oxide formation by nitric oxide synthase.
Topics: Arginine; Chromatography, High Pressure Liquid; Guanidine; Guanidines; Hydroxylamines; Kinetics; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Nitrogen Oxides; Nitrous Oxide; Spectrophotometry | 1998 |
The utilization of dipeptides containing L-arginine by chicken macrophages.
Topics: Animals; Arginine; Biological Transport; Cell Line; Chickens; Culture Media; Dipeptides; Endopeptidases; Fetal Blood; Leucine; Macrophages; Nitric Oxide; Nitrites | 1998 |
Modulation of nitric oxide improves cyclosporin A-induced hypertension in rats and primates.
Topics: Animals; Antihypertensive Agents; Arginine; Blood Pressure; Bosentan; Callithrix; Cyclosporine; Enzyme Inhibitors; Female; Hypertension; Immunosuppressive Agents; Male; Nitrates; Nitric Oxide; Nitrites; Nitroarginine; Rats; Rats, Wistar; Sulfonamides; Systole | 1998 |
Nitric oxide plays an important role in the diurnal change of tuberoinfundibular dopaminergic neuronal activity and prolactin secretion in ovariectomized, estrogen/progesterone-treated rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Arcuate Nucleus of Hypothalamus; Arginine; Circadian Rhythm; Dopamine; Estrogens; Female; Neurons; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitrites; Ovariectomy; Progesterone; Prolactin; Rats; Rats, Sprague-Dawley | 1999 |
Nitric oxide stimulates cyclic guanosine monophosphate production and electrogenic secretion in Caco-2 colonocytes.
Topics: Arginine; Caco-2 Cells; Cyclic GMP; Cystamine; Enzyme Inhibitors; Humans; Inflammatory Bowel Diseases; Intestinal Mucosa; Ion Transport; Isomerism; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrites; Nitroprusside | 1999 |
Influence of L-arginine, aminoguanidine, and NG-nitro-L-arginine methyl ester (L-name) on the survival rate in a rat model of hemorrhagic shock.
Topics: Animals; Arginine; Aspartate Aminotransferases; Blood Pressure; Creatinine; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanidines; Injections, Intravenous; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitrites; Rats; Rats, Sprague-Dawley; Shock, Hemorrhagic; Survival Rate | 1999 |
Inhibition of astroglial nitric oxide synthase type 2 expression by idazoxan.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Animals, Newborn; Arginine; Astrocytes; Cell Line; Cell-Free System; Chloramphenicol O-Acetyltransferase; Citrulline; Cytokines; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Idazoxan; Lipopolysaccharides; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitrites; Norepinephrine; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins; RNA, Messenger; Time Factors; Tumor Cells, Cultured | 1999 |
Differential expression of renal nitric oxide synthase isoforms during pregnancy in rats.
Topics: Animals; Arginine; Blood Pressure; Female; Gene Expression Regulation, Enzymologic; Hemodynamics; Kidney; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Renal Circulation; Telemetry | 1999 |
Growth of rat mesangial cells on oxidized extracellular matrix increases inducible nitric oxide synthase activity.
Topics: Animals; Arginine; Blotting, Western; Cell Division; Cell Survival; Cells, Cultured; Enzyme Activation; Extracellular Matrix; Extracellular Matrix Proteins; Glomerular Mesangium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Oxidants; Oxidation-Reduction; Rats | 1999 |
Renal vasoconstriction induced by oxidized LDL is inhibited by scavengers of reactive oxygen species and L-arginine.
Topics: Animals; Arginine; Catalase; Cyclic GMP; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Free Radical Scavengers; Glomerular Filtration Rate; Indomethacin; Lipoproteins, LDL; Male; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Renal Artery; Superoxide Dismutase; Vasoconstriction | 1999 |
Porcine endotoxemic shock is associated with increased expired nitric oxide.
Topics: Analysis of Variance; Animals; Arginine; Base Sequence; Blotting, Western; Breath Tests; Disease Models, Animal; DNA Primers; Endotoxemia; Endotoxins; Enzyme Inhibitors; Escherichia coli; Hemodynamics; Molecular Sequence Data; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Polymerase Chain Reaction; Respiration; Shock, Septic; Swine; Time Factors | 1999 |
Mean arterial blood pressure and serum levels of the molar ratio of insulin-like growth factor-1 to its binding protein-3 in healthy centenarians.
Topics: Aged; Aged, 80 and over; Arginine; Blood Flow Velocity; Blood Pressure; Body Constitution; Calcium; Endopeptidases; Erythrocytes; Female; Humans; Insulin-Like Growth Factor I; Magnesium; Male; Nitrates; Nitrites; Radioimmunoassay; Reference Values | 1999 |
Reduced arginine plasma levels are the drive for arginine production by the kidney in the rat.
Topics: Animals; Arginase; Arginine; Blood Chemical Analysis; Cattle; Citrulline; Digestive System; Endotoxemia; Kidney; Liver; Male; Nitrates; Nitrites; Ornithine; Rats; Rats, Wistar; Regional Blood Flow | 1999 |
Nitric oxide metabolites, cyclic guanosine 3,5 monophosphate and dimethylarginines during and after uncomplicated pregnancies: a longitudinal study.
Topics: Adult; Arginine; Chromatography, High Pressure Liquid; Creatinine; Cyclic GMP; Enzyme Inhibitors; Ethylenediamines; Female; Free Radical Scavengers; Humans; Immunoenzyme Techniques; Longitudinal Studies; Male; Nitrates; Nitric Oxide; Nitrites; Postpartum Period; Pregnancy; Reference Values; Sulfanilamides; Time Factors | 1999 |
Effects of ethanol on intraovarian nitric oxide production in the prepubertal rat.
Topics: Animals; Arginine; Blotting, Western; Citrulline; Estradiol; Ethanol; Female; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Ovary; Rats; Rats, Sprague-Dawley; Sexual Maturation | 1999 |
Modulation of stress-induced gastric mucosal lesions by exogenous L-arginine.
Topics: Animals; Arginine; Gastric Mucosa; Guanidines; Lipid Peroxides; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Rats; Rats, Wistar; Stress, Physiological; Thiobarbituric Acid Reactive Substances; Time Factors | 1999 |
Nitric oxide production is low in end-stage renal disease patients on peritoneal dialysis.
Topics: Adult; Aged; Arginine; Citrulline; Creatinine; Cyclic GMP; Female; Humans; Hypertension, Renal; Kidney; Kidney Failure, Chronic; Male; Middle Aged; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Oxidation-Reduction; Peritoneal Dialysis | 1999 |
N(G)-nitro-L-arginine methylester is protective against ethanol-induced gastric damage in cholestatic rats.
Topics: Alkaline Phosphatase; Animals; Arginine; Bile Ducts; Cholestasis; Drug Interactions; Drug Synergism; Ethanol; Gastric Mucosa; Ligation; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitrites; Rats | 1999 |
Stimulation of NO synthase activity in the immune-competent lepidopteran Estigmene acraea hemocyte line.
Topics: Animals; Arginine; Cell Line; Citrulline; Enzyme Activation; Enzyme Inhibitors; Hemocytes; Immunocompetence; Kinetics; Lepidoptera; NADP; Nitrates; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Superoxide Dismutase | 1999 |
No detectable NO synthesis from L-arginine or N(G)-hydroxy-L-arginine in fMLP-stimulated human blood neutrophils despite production of nitrite, nitrate, and citrulline from N(G)-hydroxy-L-arginine.
Topics: Arginine; Cells, Cultured; Citrulline; Cyclic GMP; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitrates; Nitric Oxide; Nitrites; Nitroarginine | 1999 |
Cationic proteins inhibit L-arginine uptake in rat alveolar macrophages and tracheal epithelial cells. Implications for nitric oxide synthesis.
Topics: Animals; Arginase; Arginine; Blood Proteins; Citrulline; Dose-Response Relationship, Drug; Eosinophil Granule Proteins; Epithelial Cells; Female; Fibrinolytic Agents; Gene Expression; Heparin; Lipopolysaccharides; Lung; Lysine; Macrophages, Alveolar; Male; Nitric Oxide; Nitrites; Rats; Rats, Sprague-Dawley; Ribonucleases; Time Factors; Trachea | 1999 |
Effects of L-arginine on endothelial and cardiac function in rats with heart failure.
Topics: Animals; Aorta, Thoracic; Arginine; Endothelium, Vascular; Heart; Heart Failure; Hemodynamics; Male; Myocardial Infarction; Nitrates; Nitrites; Rats; Rats, Sprague-Dawley; Vasodilation | 1999 |
Production of nitric oxide in mouse peritoneal macrophages after priming with interferon-gamma by the stem of Sinomenium acutum.
Topics: Animals; Antibodies; Arginine; Cells, Cultured; Interferon-gamma; Macrophages, Peritoneal; Mice; Neutralization Tests; Nitrates; Nitric Oxide; Nitrites; omega-N-Methylarginine; Plant Extracts; Protein Kinase Inhibitors; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1999 |
Nitric oxide in cyclosporine A-induced hypertension: endothelin receptors gene expression.
Topics: Animals; Aorta; Arginine; Cyclosporine; Gene Expression; Hypertension; Male; Nitrates; Nitric Oxide; Nitrites; Olive Oil; Plant Oils; Rats; Rats, Inbred SHR; Receptors, Endothelin; RNA, Messenger | 1999 |
Induction of nitric oxide production by natural killer cells: its role in tumor cell death.
Topics: Animals; Antibodies, Monoclonal; Apoptosis; Arginine; Cell Death; Cytotoxicity, Immunologic; Enzyme Inhibitors; Killer Cells, Natural; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Wistar; Tumor Cells, Cultured | 1999 |
Effects of daily oral doses of L-arginine on coccidiosis infections in chickens.
Topics: Animals; Arginine; Chickens; Coccidiosis; Eimeria; Eimeria tenella; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Poultry Diseases; Weight Gain | 1999 |
Amniotic fluid nitric oxide metabolites, cyclic guanosine 3',5' monophosphate and dimethylarginine in alloimmunized pregnancies.
Topics: Amniocentesis; Amniotic Fluid; Arginine; Blood Transfusion, Intrauterine; Creatinine; Cyclic GMP; Embryonic and Fetal Development; Erythroblastosis, Fetal; Female; Gestational Age; Humans; Infant, Newborn; Nitric Oxide; Nitrites; Pregnancy; Reference Values; Regression Analysis; Retrospective Studies; Rh Isoimmunization | 1999 |
Amino acid nutrition and immune function in tumour-bearing rats: a comparison of glutamine-, arginine- and ornithine 2-oxoglutarate-supplemented diets.
Topics: Analysis of Variance; Animals; Arginine; Cytokines; Cytotoxicity Tests, Immunologic; Enzyme Inhibitors; Female; Fluorescent Antibody Technique, Indirect; Glutamine; Interferon-gamma; Isothiuronium; Killer Cells, Natural; Liver Neoplasms, Experimental; Lymphocyte Activation; Macrophages, Peritoneal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Ornithine; Rats; Rats, Inbred BUF; Receptors, Interleukin-2; T-Lymphocytes; Tumor Necrosis Factor-alpha | 1999 |
Effects of endothelin-1 and nitric oxide on glucokinase activity in isolated rat hepatocytes.
Topics: Animals; Arginine; Cells, Cultured; Cyclic GMP; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Glucokinase; Glucose; Glycogen; Kinetics; Liver; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Oligopeptides; Piperidines; Rats; Rats, Sprague-Dawley | 2000 |
Possible involvement of nitric oxide in pilocarpine induced seminal emission in rats.
Topics: Animals; Arginine; Atropine; Male; Muscarinic Agonists; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitrites; Nitroprusside; Pilocarpine; Preoptic Area; Rats; Rats, Wistar; Semen | 1999 |
Antisteroidogenic action of nitric oxide on human corpus luteum in vitro: mechanism of action.
Topics: Adult; Arginine; Cells, Cultured; Corpus Luteum; Cyclic GMP; Cytochrome P-450 Enzyme System; Depression, Chemical; Enzyme Inhibitors; Estradiol; Female; Humans; Imidazoles; NADPH Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Steroids | 1999 |
Formation and reactions of the heme-dioxygen intermediate in the first and second steps of nitric oxide synthesis as studied by stopped-flow spectroscopy under single-turnover conditions.
Topics: Animals; Arginine; Catalysis; Citrulline; Ferrous Compounds; Heme; Kinetics; Models, Chemical; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitrites; Oxygen; Rats; Spectrophotometry | 2000 |
Study on the relationship between plasma nitrite and nitrate level and salt sensitivity in human hypertension : modulation of nitric oxide synthesis by salt intake.
Topics: Adult; Aged; Arginine; Blood Pressure; Electrolytes; Female; Humans; Hypertension; Lipids; Male; Middle Aged; Nitrates; Nitric Oxide; Nitrites; Norepinephrine; Renin; Smoking; Sodium Chloride, Dietary; Vascular Resistance | 2000 |
Tandem antifibrotic actions of L-arginine supplementation and low protein diet during the repair phase of experimental glomerulonephritis.
Topics: Animals; Arginine; Culture Techniques; Dietary Proteins; Fibrosis; Glomerulonephritis; Kidney; Kidney Glomerulus; Male; Nitrates; Nitrites; Proteinuria; Rats; Rats, Sprague-Dawley; Time Factors; Wound Healing | 2000 |
Glomerular basement membrane anionic sites in adriamycin nephropathy: effect of saline loading and nitric oxide modulation.
Topics: Animals; Anions; Arginine; Basement Membrane; Binding Sites; Doxorubicin; Enzyme Inhibitors; Female; Gold Colloid; Heparan Sulfate Proteoglycans; Kidney Diseases; Kidney Glomerulus; Male; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrites; Nitroarginine; Rats; Rats, Wistar; Sodium Chloride | 2000 |
Expression of a functional inducible nitric oxide synthase in hairy cell leukaemia and ESKOL cell line.
Topics: Amidines; Antibodies, Monoclonal; Apoptosis; Arginine; Benzylamines; Blotting, Western; Enzyme Induction; Enzyme Inhibitors; Fluorescent Dyes; Gene Expression Regulation, Leukemic; Humans; Leukemia, Hairy Cell; Microscopy, Fluorescence; Neoplasm Proteins; Neoplastic Stem Cells; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; omega-N-Methylarginine; Receptors, IgE; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured | 2000 |
L-Arginine increases nitric oxide production in isolated lungs of chronically hypoxic newborn pigs.
Topics: Animals; Animals, Newborn; Arginine; Chronic Disease; Hypoxia; In Vitro Techniques; Lung; Nitrates; Nitric Oxide; Nitrites; Reference Values; Swine | 2000 |
Pulmonary blast injury increases nitric oxide production, disturbs arginine metabolism, and alters the plasma free amino acid pool in rabbits during the early posttraumatic period.
Topics: Amino Acids; Animals; Arginine; Blast Injuries; Disease Models, Animal; Male; Nitrates; Nitric Oxide; Nitrites; Rabbits; Respiratory Distress Syndrome | 2000 |
Bioactive products of arginine in sepsis: tissue and plasma composition after LPS and iNOS blockade.
Topics: Animals; Arginine; Blood Pressure; Enzyme Inhibitors; Escherichia coli; Gene Expression Regulation, Enzymologic; Kidney; Kinetics; Lipopolysaccharides; Liver; Lung; Lysine; Male; Myocardium; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Ornithine; Rats; Rats, Wistar; RNA, Messenger; Sepsis | 2000 |
Assessment of nitric oxide synthase activity in vitro and in vivo by gas chromatography-mass spectrometry.
Topics: Animals; Arginine; Gas Chromatography-Mass Spectrometry; In Vitro Techniques; Male; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitrites; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity | 2000 |
L-Arginine availability modulates local nitric oxide production and parasite killing in experimental trypanosomiasis.
Topics: Animals; Arginase; Arginine; Macrophages, Peritoneal; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Trypanosoma brucei brucei; Trypanosomiasis, African | 2000 |
Changes of endothelial nitric oxide synthase level and activity during endothelial cell proliferation.
Topics: Animals; Arginine; Cattle; Cell Division; Cells, Cultured; Citrulline; Endothelium, Vascular; Kinetics; Luminescent Measurements; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Superoxide Dismutase; Superoxides | 2000 |
Supplemental dietary arginine enhances wound healing in normal but not inducible nitric oxide synthase knockout mice.
Topics: Amino Acids; Animals; Arginine; Collagen; Dietary Supplements; Hydroxyproline; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Transcription, Genetic; Weight Gain; Wound Healing; Wounds and Injuries | 2000 |
Total nitric oxide production is low in patients with chronic renal disease.
Topics: Adult; Aged; Arginine; Blood Pressure; Creatinine; Female; Humans; Hypertension, Renal; Kidney Failure, Chronic; Male; Middle Aged; Nitrates; Nitric Oxide; Nitrites; Oxidation-Reduction; Regression Analysis; Vasodilation | 2000 |
Modulation of the nitric oxide pathway by copper in glial cells.
Topics: Animals; Arginine; Citrulline; Copper; Cyclic GMP; Gene Expression Regulation, Enzymologic; Interferon-gamma; Isoenzymes; Lipopolysaccharides; Neuroglia; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitrites; Rats; RNA, Messenger; Tumor Cells, Cultured | 2000 |
Nitric oxide production by coelomocytes of Asterias forbesi.
Topics: Animals; Arginine; Blotting, Western; Culture Techniques; Interleukin-1; Mice; Molecular Weight; Nitric Oxide; Nitrites; Phagocytes; Rabbits; Starfish | 2001 |
The effect of L-arginine on intraocular pressure in the human eye.
Topics: Accommodation, Ocular; Adult; Animals; Aqueous Humor; Arginine; Female; Humans; Infusions, Intravenous; Intraocular Pressure; Male; Nitrites; Pupil; Rabbits; Reference Values; Refraction, Ocular; Tonometry, Ocular | 2000 |
Effect of Eimeria acervulina infections on plasma L-arginine.
Topics: Animals; Arginine; Carotenoids; Chickens; Coccidiosis; Eimeria; Male; Nitrates; Nitrites; Poultry Diseases; Regression Analysis; Weight Gain | 2000 |
Electrochemical detection of nitroso-arginine as an intermediate between N-hydroxy-arginine and citrulline. An in vitro versus in vivo study using microcarbon electrodes in neuronal nitric oxide synthase and mice brain.
Topics: Animals; Arginine; Brain; Brain Chemistry; Citrulline; Electrochemistry; Mice; Microelectrodes; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitrites; Nitroso Compounds; Oxidation-Reduction; Surface Properties | 2000 |
The roles played by crucial free radicals like lipid free radicals, nitric oxide, and enzymes NOS and NADPH in CCl(4)-induced acute liver injury of mice.
Topics: Alanine Transaminase; Animals; Arginine; Carbon Tetrachloride; Free Radicals; L-Lactate Dehydrogenase; Lipid Metabolism; Liver; Male; Mice; Mice, Inbred ICR; NADP; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroprusside; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2000 |
Hypercholesterolemia inhibits angiogenesis in response to hindlimb ischemia: nitric oxide-dependent mechanism.
Topics: Administration, Oral; Animals; Arginine; Body Weight; Cholesterol, Dietary; Collateral Circulation; Cyclic GMP; Endothelium, Vascular; Hindlimb; Hypercholesterolemia; Immunohistochemistry; Ischemia; Laser-Doppler Flowmetry; Lipids; Male; Neovascularization, Physiologic; Nitrates; Nitric Oxide; Nitrites; Rats; Rats, Sprague-Dawley; Regional Blood Flow | 2000 |
Hyperhomocysteinemia impairs angiogenesis in response to hindlimb ischemia.
Topics: Angiography; Animals; Arginine; Blood Pressure; Body Weight; Collateral Circulation; Cyclic GMP; Disease Models, Animal; Heart Rate; Hindlimb; Homocysteine; Hyperhomocysteinemia; Immunohistochemistry; Ischemia; Laser-Doppler Flowmetry; Muscle, Skeletal; Neovascularization, Physiologic; Nitrates; Nitrites; Rats; Regional Blood Flow; Time Factors | 2000 |
Relationship between NO synthesis, arginine transport, and intracellular arginine levels in vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Arginine; Aspartic Acid; Biological Transport; Cells, Cultured; Female; Glutamic Acid; Glutamine; Interleukin-1; Lysine; Muscle, Smooth, Vascular; Nitric Oxide; Nitrites; Ornithine; Rats; Rats, Long-Evans | 2000 |
The role of corticosterone in corticotrophin (ACTH)-induced hypertension in the rat.
Topics: Adrenocorticotropic Hormone; Animals; Arginine; Blood Pressure; Body Weight; Corticosterone; Drinking; Eating; Hypertension; Male; Nitrates; Nitrites; Nitroarginine; Rats; Rats, Sprague-Dawley; Stereoisomerism; Urination | 2000 |
Renal response during acute unilateral ureteral obstruction in rats.
Topics: Acute Disease; Animals; Arginine; Enzyme Inhibitors; Female; Glomerular Filtration Rate; Kidney; Kidney Cortex; Microcirculation; Nephrectomy; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Pressure; Rats; Rats, Wistar; Reference Values; Renal Circulation; Ureteral Obstruction | 2001 |
Paradoxical increase in nitric oxide synthase activity in hypercholesterolaemic rats with impaired renal function and decreased activity of nitric oxide.
Topics: Animals; Arginine; Cholesterol, Dietary; Cyclic GMP; Hypercholesterolemia; Kidney; Male; NADPH Dehydrogenase; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Sprague-Dawley; Reference Values | 2001 |
L-arginine attenuates lipopolysaccharide-induced lung chemokine production.
Topics: Animals; Arginine; Chemokine CXCL1; Chemokine CXCL2; Chemokines; Chemokines, CXC; Chemotactic Factors; DNA; Growth Substances; I-kappa B Proteins; Intercellular Signaling Peptides and Proteins; Lipopolysaccharides; Lung; Male; NF-kappa B; Nitrates; Nitrites; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2001 |
Nitric oxide generation by hemocytes of the mussel Mytilus galloprovincialis.
Topics: Animals; Arginine; Bivalvia; Citrulline; Enzyme Inhibitors; Hemocytes; Latex; Luminescent Measurements; Microspheres; NADPH Oxidases; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Ornithine; Phagocytosis; Superoxide Dismutase; Superoxides | 2001 |
L-arginine partially reverses established adrenocorticotrophin-induced hypertension and nitric oxide deficiency in the rat.
Topics: Adrenocorticotropic Hormone; Amino Acids; Animals; Arginine; Citrulline; Cyclic GMP; Drug Evaluation; Hypertension; Male; Nitrates; Nitric Oxide; Nitrites; Random Allocation; Rats; Rats, Sprague-Dawley; Stereoisomerism | 2000 |
Reversible sequestration of nitric oxide by hemoglobin during hemodialysis in end-stage renal disease.
Topics: Anemia; Arginine; Erythropoietin; Hematocrit; Hemoglobins; Humans; Hypotension; Kidney Failure, Chronic; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Renal Dialysis; Skin Temperature | 2001 |
Oxidations of N(omega)-hydroxyarginine analogues and various N-hydroxyguanidines by NO synthase II: key role of tetrahydrobiopterin in the reaction mechanism and substrate selectivity.
Topics: Antioxidants; Arginine; Biopterins; Guanidines; Hydroxylamines; NADP; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Oxidation-Reduction; Substrate Specificity; Superoxide Dismutase | 2001 |
Effect of oral L-arginine administration for three weeks in two kidney-two clip hypertensive rats.
Topics: Acetylcholine; Administration, Oral; Animals; Arginine; Blood Pressure; Body Weight; Epoprostenol; Hypertension; Isotonic Solutions; Kidney; Male; Muscle, Smooth, Vascular; Nitrates; Nitrites; Organ Size; Phorbol 12,13-Dibutyrate; Potassium Chloride; Protein Kinase C; Rats; Rats, Sprague-Dawley; Serotonin; Thromboxane B2; Time Factors | 2000 |
L-Arginine improves endothelial function in renal artery of hypertensive Dahl rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Arginine; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Cyclic GMP; Endothelins; Endothelium, Vascular; Fatty Acids, Unsaturated; Hydralazine; Hydrazines; Hypertension; In Vitro Techniques; Indomethacin; Male; Methacrylates; Natriuresis; Nitrates; Nitrites; Nitroprusside; Rats; Rats, Inbred Dahl; Renal Artery; Thromboxane A2; Vasoconstriction | 2001 |
Indomethacin prevents the induction of inducible nitric oxide synthase in murine peritoneal macrophages and decreases their nitric oxide production.
Topics: Animals; Arginase; Arginine; Blotting, Western; Citrulline; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Induction; Indomethacin; Macrophages, Peritoneal; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Rats; Uridine | 2001 |
Modulation of cerebellar and hepatic nitric oxide synthase by exogenous arginine and endotoxin.
Topics: Animals; Arginine; Cattle; Cerebellum; Down-Regulation; Enzyme Activation; Enzyme Induction; Lipopolysaccharides; Liver; Male; Mice; NADP; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; RNA, Messenger | 2001 |
No parallel relationship between nitric oxide production and wet dog shakes susceptible to nitric oxide synthase inhibitors following systemic administration of paraquat in rats.
Topics: Animals; Arginine; Behavior, Animal; Drug Interactions; Enzyme Inhibitors; Herbicides; Hippocampus; Injections, Subcutaneous; Male; Microinjections; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Paraquat; Rats; Rats, Sprague-Dawley; Reflex; Time Factors | 2001 |
Tetrahydrobiopterin augments arginine transport in rat cardiac myocytes through modulation of CAT-2 mRNA.
Topics: Amino Acid Transport Systems, Basic; Animals; Antioxidants; Arginine; Biological Transport; Biopterins; Carrier Proteins; Cells, Cultured; Dose-Response Relationship, Drug; Extracellular Space; Gene Expression Regulation; Lipopolysaccharides; Membrane Proteins; Myocardium; Nitrites; Protein Isoforms; Rats; Rats, Wistar; RNA, Messenger | 2001 |
Retinoic acid attenuates inducible nitric oxide synthase (NOS2) activation in cultured rat cardiac myocytes and microvascular endothelial cells.
Topics: Animals; Arginine; Blotting, Northern; Blotting, Western; Cells, Cultured; Citrulline; Dactinomycin; Endothelium, Vascular; Enzyme Activation; Interferon-gamma; Interleukin-1; Lipopolysaccharides; Macrophages, Alveolar; Male; Microcirculation; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Protein Synthesis Inhibitors; Rats; Rats, Wistar; RNA, Messenger; Time Factors; Tretinoin | 2001 |
Inhibition of nitric oxide synthase abrogates lipopolysaccharides-induced up-regulation of L-arginine uptake in rat alveolar macrophages.
Topics: Amino Acid Transport Systems, Basic; Animals; Arginine; Biological Transport; Carrier Proteins; Enzyme Inhibitors; Female; Humans; Lipopolysaccharides; Macrophages, Alveolar; Male; Membrane Potentials; Membrane Proteins; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Oocytes; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Thiazines; Xenopus laevis | 2001 |
L-Arginine given after ischaemic preconditioning can enhance cardioprotection in isolated rat hearts.
Topics: Animals; Arginine; Coronary Circulation; Enzyme Inhibitors; Heart; Hemodynamics; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrites; Rats; Rats, Wistar | 2001 |
Protective effect of L-arginine against stress-induced gastric mucosal lesions in rats and its relation to nitric oxide-mediated inhibition of neutrophil infiltration.
Topics: Animals; Arginine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gastric Mucosa; Immersion; Injections, Intraperitoneal; Male; Neutrophil Infiltration; Neutrophils; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Oxidation-Reduction; Peroxidase; Rats; Rats, Wistar; Restraint, Physical; Stress, Physiological; Time Factors | 2001 |
L-arginine polymer mediated inhibition of graft coronary artery disease after cardiac transplantation.
Topics: Animals; Aorta; Arginine; Cell Division; Cells, Cultured; Coronary Disease; Coronary Vessels; Heart Transplantation; Male; Myocardium; Nitric Oxide; Nitrites; Polymers; Rats; Rats, Inbred ACI; Rats, Inbred Strains; Rats, Sprague-Dawley | 2001 |
The role of the interaction between endogenous opioids and nitric oxide in the pathophysiology of ethanol-induced gastric damage in cholestatic rats.
Topics: Alcohol Deterrents; Animals; Arginine; Bile Ducts; Cholestasis; Disease Models, Animal; Enzyme Inhibitors; Ethanol; Gastric Mucosa; Ligation; Male; Naltrexone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitrites; Opioid Peptides; Rats; Stomach Ulcer | 2001 |
Nitric oxide synthase (NOS2) mutation in Dahl/Rapp rats decreases enzyme stability.
Topics: Amino Acid Substitution; Animals; Arginine; Blotting, Northern; COS Cells; Cysteine Endopeptidases; Enzyme Activation; Enzyme Stability; Hypertension; Immunoblotting; Lactones; Multienzyme Complexes; Mutagenesis, Site-Directed; Mutation; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Protein Synthesis Inhibitors; Rats; Rats, Inbred Dahl; RNA, Messenger; Structure-Activity Relationship; Transfection | 2001 |
N-hydroxyl derivatives of guanidine based drugs as enzymatic NO donors.
Topics: Animals; Arginine; Dioxanes; Drug Design; Drug Evaluation, Preclinical; Guanidine; Guanidines; Guinea Pigs; Horseradish Peroxidase; Hydrogen Peroxide; In Vitro Techniques; Mesenteric Arteries; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrites; Structure-Activity Relationship; Vasodilator Agents | 2001 |
Elevated serum endogenous inhibitor of nitric oxide synthase and endothelial dysfunction in aged rats.
Topics: Acetylcholine; Aging; Animals; Aorta, Thoracic; Arginine; Endothelium, Vascular; Kidney; Male; Nitric Oxide Synthase; Nitrites; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 2001 |
Endothelial dysfunction is induced by proinflammatory oxidant hypochlorous acid.
Topics: Acetylcholine; Animals; Aorta; Arginine; Biological Availability; Calcimycin; Cattle; Cells, Cultured; Endothelium, Vascular; Hypochlorous Acid; In Vitro Techniques; Inflammation Mediators; Ionophores; Male; Nitrates; Nitric Oxide; Nitrites; Nitroprusside; Oxidants; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 2001 |
Antisense knockdown of inducible nitric oxide synthase inhibits the relaxant effect of VIP in isolated smooth muscle cells of the mouse gastric fundus.
Topics: Amidines; Animals; Arginine; Benzylamines; Carbachol; Cell Size; DNA, Antisense; Enzyme Inhibitors; Female; Fluorescein-5-isothiocyanate; Gastric Fundus; Glyburide; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Muscle Relaxation; Muscle, Smooth; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Nitroarginine; Pinacidil; Tumor Necrosis Factor-alpha; Vasoactive Intestinal Peptide; Vasodilator Agents | 2001 |
Nitric oxide- and oxygen-derived free radical generation from control and lipopolysaccharide-treated rat polymorphonuclear leukocyte.
Topics: Animals; Antioxidants; Arachidonic Acid; Arginine; Biological Transport; Catalase; Enzyme Inhibitors; Flow Cytometry; Free Radicals; Guanidines; Indazoles; Lipopolysaccharides; Male; Neutrophils; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Oxygen; Peroxidase; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2001 |
Cytokine treatment increases arginine metabolism and uptake in bovine pulmonary arterial endothelial cells.
Topics: Animals; Arginine; Cationic Amino Acid Transporter 2; Cattle; Cells, Cultured; Endothelium, Vascular; Lipopolysaccharides; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitrogen Dioxide; Pulmonary Artery; Tumor Necrosis Factor-alpha; Urea | 2001 |
Nitrite/Nitrate responses to endotoxin in calves.
Topics: Age Factors; Animals; Arginine; Cattle; Endotoxins; Escherichia coli; Iron; Male; Nitrates; Nitric Oxide Synthase; Nitrites; Tumor Necrosis Factor-alpha | 2001 |
L-Arginine is not the limiting factor for nitric oxide synthesis by human alveolar macrophages in vitro.
Topics: Animals; Arginase; Arginine; Cattle; Cell Line; Fetal Blood; Guanidines; Humans; Hydrogen Peroxide; In Vitro Techniques; Macrophages; Macrophages, Alveolar; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitrites | 2001 |
L-citrulline mediated relaxation in the control and lipopolysaccharide-treated rat aortic rings.
Topics: Animals; Aorta; Arginine; Citrulline; Corticosterone; Cyclic GMP; Cycloheximide; Glutamine; Guanidines; In Vitro Techniques; Lipopolysaccharides; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitrites; Potassium Channels; Rats; Rats, Sprague-Dawley; Vasodilation | 2001 |
Two-way arginine transport in human endothelial cells: TNF-alpha stimulation is restricted to system y(+).
Topics: Amino Acid Transport System y+; Amino Acid Transport System y+L; Amino Acid Transport Systems, Basic; Antineoplastic Agents; Arginine; Biological Transport; Carrier Proteins; Cationic Amino Acid Transporter 1; Cationic Amino Acid Transporter 2; Cells, Cultured; DNA Primers; Endothelium, Vascular; Enzyme Inhibitors; Ethylmaleimide; Fusion Regulatory Protein 1, Light Chains; Gene Expression; Humans; Lipopolysaccharides; Membrane Proteins; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Tumor Necrosis Factor-alpha; Umbilical Veins | 2002 |
Effect of nitric oxide on iron-mediated cytotoxicity in primary cultured renal proximal tubules.
Topics: Animals; Arginine; Carcinogens; Cells, Cultured; Drug Interactions; Enzyme Inhibitors; Ferric Compounds; Free Radical Scavengers; Glutathione; Kidney Tubules, Proximal; L-Lactate Dehydrogenase; Lipopolysaccharides; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrilotriacetic Acid; Nitrites; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Thiourea | 2001 |
Low exhaled nitric oxide and a polymorphism in the NOS I gene is associated with acute chest syndrome.
Topics: Acute Disease; Adolescent; Anemia, Sickle Cell; Arginine; Breath Tests; Child; Citrulline; Forced Expiratory Volume; Genotype; Humans; Lung Diseases; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitrites; Polymorphism, Genetic; Syndrome; Trinucleotide Repeats; Vital Capacity | 2001 |
Angiotensin II type 1 receptor blockade ameliorates tubulointerstitial injury induced by chronic potassium deficiency.
Topics: Angiotensin Receptor Antagonists; Animals; Arginine; Chronic Disease; Dinoprostone; Kidney; Losartan; Male; Nitrates; Nitrites; Potassium Deficiency; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1 | 2002 |
A brain nitric oxide synthase study in the rat: production of a nitroso-compound NA and absence of nitric oxide synthesis.
Topics: Animals; Arginine; Brain; Citrulline; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Nitroso Compounds; Rats | 2002 |
Biochemical markers of the L-arginine-nitric oxide pathway in the aqueous humour in glaucoma patients.
Topics: Aged; Aqueous Humor; Arginine; Biomarkers; Blood Pressure; Cataract; Cyclic GMP; Female; Glaucoma; Humans; Intraocular Pressure; Male; Nitrates; Nitric Oxide; Nitrites; Prospective Studies; Signal Transduction | 2002 |
all-trans-Retinoic acid increases nitric oxide synthesis by endothelial cells: a role for the induction of dimethylarginine dimethylaminohydrolase.
Topics: Amidohydrolases; Arginine; Blotting, Northern; Cell Line; Endothelium, Vascular; Enzyme Induction; Enzyme Inhibitors; Genes, Reporter; Isoenzymes; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Promoter Regions, Genetic; RNA, Messenger; Tretinoin | 2002 |
Nitric oxide inhibits the shedding of the glycosylphosphatidylinositol-anchored dipeptidase from porcine renal proximal tubules.
Topics: Animals; Arginine; Blotting, Western; Deferoxamine; Dithiothreitol; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estrenes; Glycosylphosphatidylinositols; Kidney; Kidney Tubules; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitrites; Nitroprusside; Penicillamine; Phosphodiesterase Inhibitors; Protein Binding; Pyrrolidinones; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; Superoxide Dismutase; Swine; Time Factors; Type C Phospholipases | 2002 |
Increased plasma nitrites in migraine and cluster headache patients in interictal period: basal hyperactivity of L-arginine-NO pathway?
Topics: Adult; Arginine; Cluster Headache; Female; Humans; Male; Middle Aged; Migraine Disorders; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Reference Values | 2002 |
Effects of arginine supplementation on antioxidant enzyme activity and macrophage response in burned mice.
Topics: Animals; Arginine; Burns; Dietary Supplements; Macrophage Activation; Macrophages; Male; Mice; Mice, Inbred BALB C; Nitrites; Oxidoreductases; Superoxide Dismutase; Time Factors; Tumor Necrosis Factor-alpha | 2002 |
Inhibition of mesangial iNOS by reduced extracellular pH is associated with uncoupling of NADPH oxidation.
Topics: Animals; Arginine; Cells, Cultured; Extracellular Space; Gene Expression; Glomerular Mesangium; Hydrogen; Hydrogen-Ion Concentration; Mice; NADP; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Oxidation-Reduction; Rats; Species Specificity | 2002 |
Electrochemical and peroxidase oxidation study of N'-hydroxyguanidine derivatives as NO donors.
Topics: Arginine; Cytochrome P-450 Enzyme System; Electrochemistry; Free Radicals; Guanidines; Horseradish Peroxidase; Hydrogen Peroxide; Hydroxylamines; Iron; NADP; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrites; Oxidation-Reduction | 2002 |
Chronic feeding of a nitric oxide synthase inhibitor induces postprandial hypertriglyceridemia in type 2 diabetic model rats, Otsuka Long-Evans Tokushima Fatty rats, but not in nondiabetic rats.
Topics: Animals; Arginine; Blood Glucose; Blood Pressure; Body Weight; Diabetes Mellitus; Diabetes Mellitus, Type 2; Dietary Fats; Disease Models, Animal; Eating; Enzyme Inhibitors; Hypertriglyceridemia; Insulin; Lipid Metabolism; Lipids; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrites; Obesity; Postprandial Period; Rats; Rats, Inbred OLETF; Rats, Long-Evans; Species Specificity; Time | 2002 |
Short-time non-enzymatic nitric oxide synthesis from L-arginine and hydrogen peroxide induced by shock waves treatment.
Topics: Acoustics; Arginine; Fluorometry; Hydrogen Peroxide; Nitric Oxide; Nitrites; Time Factors | 2002 |
Aging-induced phenotypic changes and oxidative stress impair coronary arteriolar function.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Aging; Animals; Arginine; Arterioles; Blotting, Western; Bridged Bicyclo Compounds, Heterocyclic; Coronary Vessels; Enzyme Inhibitors; Fatty Acids, Unsaturated; Hydrazines; Immunohistochemistry; In Vitro Techniques; Male; Multienzyme Complexes; NADH, NADPH Oxidoreductases; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrites; Oxidative Stress; Phenotype; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA, Messenger; Superoxide Dismutase; Tyrosine; Vasodilation; Xanthine Oxidase | 2002 |
Reduced nitric oxide synthase activity in rats with chronic renal disease due to glomerulonephritis.
Topics: Animals; Antibodies; Arginine; Autoantibodies; Blood Urea Nitrogen; Creatinine; Glomerulonephritis; Kidney Failure, Chronic; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitrites; Proteinuria; Rats; Rats, Sprague-Dawley | 2002 |
[Nitric oxide modulates expression of matrix metalloproteinase in asthmatic rats].
Topics: Animals; Arginine; Asthma; Bronchoalveolar Lavage Fluid; Gene Expression Regulation; Lung; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinases; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Wistar; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-1 | 2002 |
The effects of antioxidants and nitric oxide modulators on hepatic ischemic-reperfusion injury in rats.
Topics: Animals; Antioxidants; Arginine; Ascorbic Acid; Catalase; Enzyme Inhibitors; Liver; Male; Malondialdehyde; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Nitroarginine; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tumor Necrosis Factor-alpha; Vitamin E | 2002 |
Blockade of the L-arginine/NO synthase pathway worsens hepatic apoptosis and liver transplant preservation injury.
Topics: Animals; Apoptosis; Arginase; Arginine; Enzyme Inhibitors; Liver; Liver Transplantation; Male; Necrosis; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Rats; Rats, Inbred Lew; Up-Regulation | 2002 |
The molecular site of action of K(ATP) channel inhibitors determines their ability to inhibit iNOS-mediated relaxation in rat aorta.
Topics: 4-Aminopyridine; Adenosine Triphosphate; Aminopyridines; Analysis of Variance; Animals; Aorta; Arginine; Barium; Endothelium, Vascular; Glyburide; Guanidines; Lipopolysaccharides; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley; Tolbutamide; Vasodilator Agents | 2002 |
Inducible nitric oxide synthase is expressed in synovial fluid granulocytes.
Topics: Adult; Aged; Arginine; Arthritis, Rheumatoid; Autoimmune Diseases; Blood Cells; Chromatography, High Pressure Liquid; Citrulline; Colorimetry; Enzyme Induction; Exudates and Transudates; Female; Granulocytes; Humans; Knee; Male; Membrane Proteins; Middle Aged; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Organ Specificity; Synovial Fluid | 2002 |
L-Arginine effects on blood pressure and renal function of intrauterine restricted rats.
Topics: Animals; Arginine; Blood Pressure; Female; Food Deprivation; Glomerular Filtration Rate; Kidney; Kidney Function Tests; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitrites; Organ Size; Placental Insufficiency; Pregnancy; Proteinuria; Rats; Weight Gain | 2002 |
Cerebrospinal fluid and plasma concentrations of nitric oxide metabolites are increased in dementia with Lewy bodies.
Topics: Aged; Arginine; Citrulline; Female; Humans; Lewy Body Disease; Male; Nitrates; Nitrites | 2002 |
Plasma concentration of asymmetric dimethylarginine, an endogenous inhibitor of nitric oxide synthase, is elevated in hyperthyroid patients.
Topics: Adult; Aged; Arginine; Female; Humans; Hyperthyroidism; Hypothyroidism; Male; Middle Aged; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Osmolar Concentration; Reference Values | 2002 |
Effect of L-arginine or nitroglycerine during deep hypothermic circulatory arrest in neonatal lambs.
Topics: Animals; Animals, Newborn; Arginine; Heart Arrest, Induced; Hypothermia, Induced; Lung Compliance; Malondialdehyde; Nitrates; Nitrites; Nitroglycerin; Pulmonary Circulation; Sheep; Stroke Volume; Vascular Resistance | 2003 |
Long-term dietary L-arginine supplementation attenuates proteinuria and focal glomerulosclerosis in experimental chronic renal transplant failure.
Topics: Animals; Arginine; Blood Pressure; Creatine; Dietary Supplements; Disease Models, Animal; Glomerulosclerosis, Focal Segmental; Kidney Failure, Chronic; Kidney Transplantation; Male; Nitrates; Nitrites; Proteinuria; Rats; Rats, Inbred F344 | 2003 |
L-arginine supplementation accelerates renal fibrosis and shortens life span in experimental lupus nephritis.
Topics: Albuminuria; Amino Acids; Animals; Arginine; Autoantibodies; Blood Urea Nitrogen; DNA; Extracellular Matrix; Female; Fibronectins; Fibrosis; Immunoglobulin G; Leukocytes, Mononuclear; Lupus Nephritis; Mice; Mice, Inbred MRL lpr; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Plasminogen Activator Inhibitor 1; RNA, Messenger; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2003 |
Significance of asymmetric dimethylarginine (ADMA) concentrations during coronary circulation in patients with vasospastic angina.
Topics: Aged; Angina Pectoris; Arginine; Case-Control Studies; Coronary Angiography; Coronary Circulation; Coronary Vasospasm; Coronary Vessels; Enzyme Inhibitors; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitrates; Nitrites; Osmolar Concentration; Risk Factors; Vasodilator Agents; Vasomotor System | 2003 |
[The effects of nitric oxide on the survival of a random pattern skin flap].
Topics: Animals; Arginine; Dermatologic Surgical Procedures; Enzyme Inhibitors; Female; Graft Survival; Immunohistochemistry; Male; Microscopy, Electron; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Wistar; Skin; Skin Transplantation; Surgical Flaps | 2002 |
Induction of LOX-1 and iNOS expressions by ischemia-reperfusion of rat kidney and the opposing effect of L-arginine.
Topics: Animals; Arginine; Biopterins; Gene Expression Regulation; Kidney; Male; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Rats; Rats, Wistar; Receptors, LDL; Receptors, Oxidized LDL; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Scavenger Receptors, Class E; Superoxide Dismutase; Time Factors | 2003 |
Acute inhibition of myoglobin impairs contractility and energy state of iNOS-overexpressing hearts.
Topics: Adenosine Triphosphate; Animals; Arginine; Carbon Dioxide; Carbon Monoxide; Enzyme Inhibitors; Genotype; Heart; In Vitro Techniques; Isothiuronium; Magnetic Resonance Spectroscopy; Metmyoglobin; Mice; Mice, Transgenic; Myocardial Contraction; Myocardium; Myoglobin; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Nitrogen; Oxygen; Perfusion; Phosphocreatine; Ventricular Pressure | 2003 |
Characterization of Drosophila nitric oxide synthase: a biochemical study.
Topics: Animals; Arginine; Biopterins; Dose-Response Relationship, Drug; Drosophila; Electrons; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Heme; Hydrogen Peroxide; Hydrolysis; NADP; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Open Reading Frames; Protein Structure, Tertiary; Spectrophotometry; Time Factors; Trypsin; Ultraviolet Rays; Urea | 2003 |
Protective effect of dietary nitrate on experimental gastritis in rats.
Topics: Animals; Arginine; Diet; Gastric Mucosa; Gastritis; Hemoglobins; Iodoacetamide; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrites; Nitroprusside; Potassium Compounds; Rats; Rats, Wistar; Stomach | 2003 |
Vaccinia virus-induced inhibition of nitric oxide production.
Topics: Animals; Arginine; Cell Line; Cell Survival; Enzyme Inhibitors; Interferon-gamma; Interleukin-1; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; omega-N-Methylarginine; Tumor Necrosis Factor-alpha; Ultraviolet Rays; Vaccinia virus | 2003 |
NO mediates antifibrotic actions of L-arginine supplementation following induction of anti-thy1 glomerulonephritis.
Topics: Animals; Arginine; Blood Pressure; Body Weight; Enzyme Inhibitors; Fibronectins; Fibrosis; Gene Expression; Glomerulonephritis; Isoantibodies; Male; Molsidomine; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitrites; Plasminogen Activator Inhibitor 1; Proteinuria; Rats; Rats, Wistar; RNA, Messenger; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2003 |
Characterization of suppression of nitric oxide production by carbon monoxide poisoning in the striatum of free-moving rats, as determined by in vivo brain microdialysis.
Topics: Animals; Arginine; Carbon Monoxide Poisoning; Citrulline; Corpus Striatum; Extracellular Space; Isomerism; Male; Microdialysis; Movement; Nitrates; Nitric Oxide; Nitrites; Rats; Rats, Sprague-Dawley | 2003 |
L-arginine in focal cerebral ischemia.
Topics: Animals; Arginine; Brain Edema; Brain Ischemia; Neuroprotective Agents; Nitrates; Nitric Oxide; Nitrites; Oxygen; Rabbits | 2003 |
Effects of iNOS-related NO on hearts exposed to liposoluble iron.
Topics: Animals; Arginine; Heart; Heart Ventricles; Hydroxybenzoates; Hydroxyl Radical; Immunoblotting; Iron; Lipopolysaccharides; Myocardial Contraction; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Nitroarginine; Oxidative Stress; Perfusion; Rats; Rats, Wistar; Reperfusion Injury; Salicylic Acid; Time Factors | 2003 |
[The effects of L-arginine and NG-nitro-L-arginine methylester on lipopolysaccharide and lipoteichoic acid induced liver injury in the rat].
Topics: Animals; Arginine; Disease Models, Animal; Enzyme Inhibitors; Lipopolysaccharides; Liver; Liver Function Tests; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitrites; Random Allocation; Rats; Rats, Wistar; Shock, Septic; Teichoic Acids | 2003 |
Changes in some indices of the synthesis of nitric oxide during the early stages of hepatocarcinogenesis.
Topics: Administration, Oral; Animals; Arginine; Carcinogens; Catalase; Diethylnitrosamine; Lipid Peroxidation; Liver; Liver Neoplasms; Male; Malondialdehyde; Nitric Oxide; Nitrites; Rats; Rats, Wistar; Superoxide Dismutase; Time Factors | 2003 |
[Role of the L-arginine-NO system in the prevention and treatment of cardiovascular diseases in pregnant women].
Topics: Arginine; Circadian Rhythm; Female; Health Resorts; Humans; Nitrates; Nitric Oxide; Nitrites; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Saliva | 2003 |
Evidence for dysregulation of dimethylarginine dimethylaminohydrolase I in chronic hypoxia-induced pulmonary hypertension.
Topics: Amidohydrolases; Animals; Arginine; Blotting, Western; Chronic Disease; Disease Models, Animal; Enzyme Activation; Hypertension, Pulmonary; Hypoxia; Isoenzymes; Lung; Male; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Rats; Rats, Sprague-Dawley | 2003 |
Endothelial dysfunction and reduced nitric oxide in resistance arteries in autosomal-dominant polycystic kidney disease.
Topics: Adult; Arginine; Arteries; Endothelium, Vascular; Female; Humans; Hypertension; Kidney Failure, Chronic; Male; Middle Aged; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Polycystic Kidney, Autosomal Dominant; Vascular Resistance; Vasodilation | 2003 |
AMINO-ACIDS AND PEPTIDES. XXI. REMOVAL OF THE NITRO-GROUP FROM NITROARGININE AND PEPTIDES OF NITROARGININE BY ELECTROLYTIC REDUCTION.
Topics: Amino Acids; Arginine; Chemical Phenomena; Chemistry; Electrolysis; Nitrites; Nitroarginine; Oxidation-Reduction; Peptides; Research | 1965 |
NEW SAKAGUCHI REACTION.
Topics: Acetates; Amino Acids; Arginine; Colorimetry; Glycine; Indicators and Reagents; Nitrites; Potassium; Research | 1965 |
SIMULTANEOUS INDUCTION AND REPRESSION OF NITRATE REDUCTASE AND TPNH CYTOCHROME REDUCTASE IN NEUROSPORA CRASSA.
Topics: Adenine; Alanine; Ammonia; Arginine; Aspartic Acid; Cytochrome Reductases; Cytochromes; Electron Transport; Enzyme Repression; Flavin-Adenine Dinucleotide; Hot Temperature; Kinetics; Lyases; Molecular Biology; Mutation; NADP; Neurospora; Neurospora crassa; Nitrate Reductase; Nitrate Reductases; Nitrates; Nitrites; Oxidoreductases; Pharmacology; Proteins; Research | 1965 |
Depletion of serum L-arginine in patients with acute pancreatitis.
Topics: Acute Disease; Adolescent; Adult; Aged; Alcoholism; Amylases; Arginine; C-Reactive Protein; Cholecystitis, Acute; Citrulline; Female; Gallstones; Humans; Male; Middle Aged; Nitrates; Nitrites; Pancreatitis; Pancreatitis, Alcoholic; Recurrence; Time Factors | 2003 |
Factors involved in the development of hypertension induced by a low-protein diet in rats with renal injury.
Topics: Animals; Arginine; Blood Pressure; Cyclosporine; Diet, Protein-Restricted; Dietary Supplements; Hypertension; Kidney; Kidney Diseases; Male; Nitrates; Nitric Oxide; Nitrites; Rats; Rats, Sprague-Dawley; Sucrose | 2004 |
Relationship between protective effect of xanthone on endothelial cells and endogenous nitric oxide synthase inhibitors.
Topics: Amidohydrolases; Arginine; Cell Adhesion; Cells, Cultured; Chemokine CCL2; Endothelium, Vascular; Enzyme Inhibitors; L-Lactate Dehydrogenase; Monocytes; Nitrates; Nitric Oxide Synthase; Nitrites; Tumor Necrosis Factor-alpha; Xanthones | 2003 |
Ability of tetrahydrobiopterin analogues to support catalysis by inducible nitric oxide synthase: formation of a pterin radical is required for enzyme activity.
Topics: Amino Acids; Arginine; Binding Sites; Biopterins; Catalysis; Dithionite; Electron Spin Resonance Spectroscopy; Enzyme Activation; Free Radicals; Freezing; Heme; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Oxyhemoglobins; Protein Structure, Tertiary; Pterins; Recombinant Proteins; Time Factors | 2003 |
Activation of nitric oxide-cyclic guanosine monophosphate signaling in kidney by extracorporeal shock wave therapy.
Topics: Animals; Arginine; Cyclic GMP; Enzyme Inhibitors; Kidney; Lithotripsy; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Oxadiazoles; Quinoxalines; Rabbits; Signal Transduction | 2003 |
Myeloperoxidase up-regulates the catalytic activity of inducible nitric oxide synthase by preventing nitric oxide feedback inhibition.
Topics: Animals; Arginine; Catalysis; Chromatography, High Pressure Liquid; Citrulline; Electrochemistry; Escherichia coli; Feedback, Physiological; Hydrogen Peroxide; Inflammation; Kinetics; Mice; Milk; Models, Biological; Models, Chemical; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Oxygen; Peroxidase; Protein Binding; RNA, Messenger; Spectrophotometry; Time Factors; Ultraviolet Rays; Up-Regulation | 2003 |
Plasma arginine and urinary nitrate and nitrite excretion in bronchopulmonary dysplasia.
Topics: Arginine; Blood Flow Velocity; Bronchopulmonary Dysplasia; Chromatography, Ion Exchange; Echocardiography; Gas Chromatography-Mass Spectrometry; Humans; Infant, Newborn; Infant, Premature; Nitrates; Nitrites; Prospective Studies; Pulmonary Artery; Statistics, Nonparametric; Ultrasonography, Doppler | 2004 |
NapGH components of the periplasmic nitrate reductase of Escherichia coli K-12: location, topology and physiological roles in quinol oxidation and redox balancing.
Topics: Arginine; Base Sequence; Electron Transport; Escherichia coli; Escherichia coli Proteins; Genes, Bacterial; Molecular Sequence Data; Mutagenesis, Site-Directed; Nitrate Reductase; Nitrate Reductases; Nitrites; Operon; Oxidation-Reduction; Oxidoreductases; Periplasmic Proteins; Protein Structure, Secondary; Recombinant Fusion Proteins; Subcellular Fractions; Two-Hybrid System Techniques; Ubiquinone | 2004 |
Cytomegalovirus infection impairs the nitric oxide synthase pathway: role of asymmetric dimethylarginine in transplant arteriosclerosis.
Topics: Amidohydrolases; Arginine; Cardiovascular Diseases; Cells, Cultured; Coronary Angiography; Coronary Artery Disease; Cyclic GMP; Cytomegalovirus Infections; Endothelium, Vascular; Female; Heart Transplantation; Humans; Male; Middle Aged; Nitric Oxide Synthase; Nitrites; Oxidative Stress; Risk Factors; Signal Transduction | 2004 |
Arginase inhibition increases nitric oxide production in bovine pulmonary arterial endothelial cells.
Topics: Animals; Arginase; Arginine; Cattle; Cells, Cultured; Dose-Response Relationship, Drug; Drug Combinations; Endothelium, Vascular; Isoenzymes; Lipopolysaccharides; Nitrates; Nitric Oxide; Nitrites; Osmolar Concentration; Pulmonary Artery; RNA, Messenger; Time Factors; Tumor Necrosis Factor-alpha; Urea; Valine | 2004 |
The role of the arginine-nitric oxide pathway in the pathogenesis of bipolar affective disorder.
Topics: Adult; Analysis of Variance; Arginine; Bipolar Disorder; Case-Control Studies; Diagnostic and Statistical Manual of Mental Disorders; Female; Humans; Male; Manganese; Middle Aged; Nitric Oxide; Nitrites; Sex Factors | 2004 |
Nitric oxide synthesis is blocked in the enteral nervous system during dormant periods of the snail Helix lucorum.
Topics: Animals; Arginine; Enteric Nervous System; Helix, Snails; Muscle Contraction; NADPH Dehydrogenase; Neurons; Nitric Oxide; Nitrites; Nitroarginine | 2004 |
Cobalt-60 gamma radiation increased the nitric oxide generation in cultured rat vascular smooth muscle cells.
Topics: Animals; Aorta, Thoracic; Arginine; Cells, Cultured; Cobalt Radioisotopes; Cyclic GMP; DNA Primers; DNA, Complementary; Gamma Rays; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Up-Regulation | 2004 |
Nitric oxide and vascular hypertrophy.
Topics: Animals; Arginine; Carotid Arteries; Cell Cycle; Cell Size; Cells, Cultured; Endothelium, Vascular; G1 Phase; Hypertrophy; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Ploidies; Proteins; Rats; Rats, Inbred SHR; Time Factors | 2004 |
Chronic l-arginine treatment reduces vascular smooth muscle cell hypertrophy through cell cycle modifications in spontaneously hypertensive rats.
Topics: Animals; Arginine; Carotid Arteries; Cell Cycle; Cell Division; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Enzyme Induction; G1 Phase; Hypertrophy; Male; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide Synthase; Nitrites; Ploidies; Rats; Rats, Inbred SHR; Time Factors | 2004 |
Nitration of a peptide phytotoxin by bacterial nitric oxide synthase.
Topics: Arginine; Gene Deletion; Genes, Bacterial; Indoles; Molecular Sequence Data; Nitrates; Nitric Oxide Synthase; Nitrites; Nitrogen; Piperazines; Plants; Streptomyces; Toxins, Biological | 2004 |
Measurement of nitric oxide synthase activity in vivo and in vitro by gas chromatography-mass spectrometry.
Topics: Animals; Arginine; Blood Platelets; Fluorobenzenes; Gas Chromatography-Mass Spectrometry; Humans; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitrogen Isotopes; Peroxynitrous Acid | 2004 |
Increased (E)-4-hydroxy-2-nonenal and asymmetric dimethylarginine concentrations and decreased nitric oxide concentrations in the plasma of patients with major depression.
Topics: Aldehydes; Arginine; Citrulline; Coronary Disease; Depressive Disorder, Major; Female; Glutathione; Humans; Lipid Peroxidation; Male; Middle Aged; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites | 2004 |
Asymmetric dimethylarginine produces vascular lesions in endothelial nitric oxide synthase-deficient mice: involvement of renin-angiotensin system and oxidative stress.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Coronary Disease; Enzyme Induction; Homocysteine; Imidazoles; Infusion Pumps, Implantable; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microcirculation; Myocardium; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Olmesartan Medoxomil; omega-N-Methylarginine; Oxidative Stress; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Superoxides; Tetrazoles; Thiazepines | 2004 |
Plasma concentrations of nitric oxide and asymmetric dimethylarginine in human alcoholic cirrhosis.
Topics: Arginine; Endothelium, Vascular; Female; Humans; Liver Cirrhosis, Alcoholic; Male; Middle Aged; Nitrates; Nitric Oxide; Nitrites; Vasodilation | 2004 |
Different response to exogenous L-arginine in nitric oxide production between hippocampus and striatum of conscious rats: a microdialysis study.
Topics: Analysis of Variance; Animals; Arginine; Chromatography, High Pressure Liquid; Corpus Striatum; Drug Interactions; Enzyme Inhibitors; Hippocampus; Male; Microdialysis; Nitrates; Nitric Oxide; Nitrites; Nitroarginine; Rats; Rats, Sprague-Dawley; Time Factors; Wakefulness | 2004 |
Effect of fenofibrate on LDL-induced endothelial dysfunction in rats.
Topics: Acetylcholine; Animals; Anti-Inflammatory Agents; Aorta, Thoracic; Arginine; Creatinine; Endothelium, Vascular; Fenofibrate; Hypolipidemic Agents; In Vitro Techniques; Male; Malondialdehyde; Muscle, Smooth, Vascular; Nitrates; Nitrites; Phenylephrine; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha; Vasodilation | 2004 |
No hemoglobin but NO: the icefish (Chionodraco hamatus) heart as a paradigm.
Topics: Animals; Antarctic Regions; Arginine; Cardiotonic Agents; Cell Respiration; Cyclic GMP; Electrochemistry; Fluorescent Antibody Technique; Molsidomine; Myocardial Contraction; Myocardium; NADH Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Oceans and Seas; Ornithine; Perciformes | 2004 |
Reducing arginase activity via dietary manganese deficiency enhances endothelium-dependent vasorelaxation of rat aorta.
Topics: Animals; Aorta; Arginase; Arginine; Coronary Vessels; Diet; Endothelium, Vascular; Enzyme Inhibitors; Immunohistochemistry; Manganese; Nitrates; Nitric Oxide Synthase; Nitrites; Rats; Vasodilation | 2004 |
Relationship of asymmetric dimethylarginine to haemodialysis hypotension.
Topics: Aged; Arginine; Female; Humans; Hypotension; Male; Nitrates; Nitrites; Renal Dialysis; Tumor Necrosis Factor-alpha | 2004 |
Dexamethasone suppresses eNOS and CAT-1 and induces oxidative stress in mouse resistance arterioles.
Topics: Acetylcholine; Animals; Antioxidants; Arginine; Arterioles; Ascorbic Acid; Cationic Amino Acid Transporter 1; Cells, Cultured; Dexamethasone; Endothelial Cells; Glucocorticoids; Humans; Mice; Mice, Inbred C57BL; Myocardium; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Oxidative Stress; Vascular Resistance; Vasodilation | 2005 |
A reduction of endogenous asymmetric dimethylarginine contributes to the effect of captopril on endothelial dysfunction induced by homocysteine in rats.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Captopril; Creatinine; Dose-Response Relationship, Drug; Endothelium, Vascular; Homocysteine; In Vitro Techniques; Liver; Male; Malondialdehyde; Nitrates; Nitric Oxide Synthase; Nitrites; Peptidyl-Dipeptidase A; Phenylephrine; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Vasoconstriction; Vasodilator Agents | 2005 |
The transport of cationic amino acids in human airway cells: expression of system y+L activity and transepithelial delivery of NOS inhibitors.
Topics: Adenocarcinoma; Amino Acid Transport System y+L; Amino Acids; Animals; Arginine; Biological Transport; Cations; Cell Line; Cell Line, Tumor; Cell Membrane Permeability; Culture Media, Conditioned; Epithelial Cells; Gene Expression; Humans; Lung Neoplasms; Lysine; Macrophages; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; omega-N-Methylarginine; Respiratory System; Reverse Transcriptase Polymerase Chain Reaction | 2005 |
Asymmetric dimethylarginine is not involved in ovariectomy-induced osteopenia in rats.
Topics: Animals; Arginine; Bone and Bones; Bone Density; Bone Diseases, Metabolic; Estrogens; Female; Nitrates; Nitrites; Ovariectomy; Rats; Rats, Sprague-Dawley | 2005 |
Overexpression of dimethylarginine dimethylaminohydrolase reduces tissue asymmetric dimethylarginine levels and enhances angiogenesis.
Topics: Amidohydrolases; Animals; Arginine; Enzyme Induction; Female; Hindlimb; Humans; Ischemia; Laser-Doppler Flowmetry; Mice; Mice, Transgenic; Microspheres; Muscle, Skeletal; Neovascularization, Physiologic; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Prostheses and Implants; Recombinant Fusion Proteins | 2005 |
[Role of nitric oxide and lipid peroxidation in pathogenesis of acute experimental pancreatitis].
Topics: Animals; Arginine; Disease Models, Animal; Lipid Peroxidation; Lipid Peroxides; Male; Methylene Blue; Nitrates; Nitric Oxide; Nitrites; Pancreatitis, Acute Necrotizing; Rats; Rats, Wistar | 2005 |
Direct single cell determination of nitric oxide synthase related metabolites in identified nitrergic neurons.
Topics: Animals; Arginine; Argininosuccinic Acid; Cells, Cultured; Citrulline; Electric Conductivity; Electrophoresis, Capillary; Ganglia, Invertebrate; Intracellular Fluid; Lymnaea; Microscopy, Fluorescence; Nitrates; Nitrergic Neurons; Nitric Oxide Synthase; Nitrites; Ornithine | 2005 |
Pulmonary vascular dilation induced by L-ARGININE: correlation with induction of endothelial nitric oxide synthase in a rabbit model.
Topics: Administration, Oral; Animals; Arginine; Female; Lung; Models, Animal; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Pulmonary Artery; Rabbits; Tomography, X-Ray Computed; Vasodilation | 2005 |
Dietary arginine supplementation attenuates renal damage after relief of unilateral ureteral obstruction in rats.
Topics: Animals; Arginine; Cyclic GMP; Dietary Supplements; Enzyme Inhibitors; Fibroblasts; Fibrosis; Glomerular Filtration Rate; In Situ Nick-End Labeling; Kidney; Macrophages; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Organ Size; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta; Transforming Growth Factor beta1; Ureteral Obstruction | 2005 |
Protective effects of L-arginine on pulmonary oxidative stress and antioxidant defenses during exhaustive exercise in rats.
Topics: Analysis of Variance; Animals; Antioxidants; Arginine; Catalase; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Lipid Peroxidation; Lung; Male; Malondialdehyde; Nitrates; Nitrites; Oxidative Stress; Peroxidase; Physical Conditioning, Animal; Proteins; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Uric Acid; Xanthine Oxidase | 2005 |
Systemic administration of L-arginine benefits mdx skeletal muscle function.
Topics: Analysis of Variance; Animals; Arginine; Blotting, Western; Calcium-Transporting ATPases; Creatine Kinase; Dystrophin; Evans Blue; Gene Expression Regulation; Immunohistochemistry; Indoles; Male; Mice; Mice, Inbred mdx; Muscle Contraction; Muscle, Skeletal; Muscular Dystrophy, Animal; Nitrates; Nitrites; Sarcoglycans; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Utrophin; Vinculin | 2005 |
Dimethylarginine dimethylaminohydrolase overexpression suppresses graft coronary artery disease.
Topics: Amidohydrolases; Animals; Arginine; Coronary Artery Disease; Cytokines; Enzyme Inhibitors; Female; Heart; Heart Transplantation; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myocarditis; Myocardium; Nitrates; Nitric Oxide Synthase; Nitrites; Osmolar Concentration; Postoperative Period; Pregnancy; Superoxides; Time Factors; Transplantation, Heterotopic; Transplantation, Homologous; Tumor Necrosis Factor-alpha | 2005 |
l-Citrulline and l-arginine supplementation retards the progression of high-cholesterol-diet-induced atherosclerosis in rabbits.
Topics: Animals; Antioxidants; Aorta, Thoracic; Arginine; Arteriosclerosis; Ascorbic Acid; Citrulline; Cyclic AMP Response Element-Binding Protein; Cyclic GMP; Diet, Atherogenic; DNA-Binding Proteins; Endothelium, Vascular; ets-Domain Protein Elk-1; Humans; Male; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Oxidation-Reduction; Proto-Oncogene Proteins; Rabbits; Superoxides; Transcription Factors; Vasodilation; Vitamin E | 2005 |
Modulatory role of green tea extract on antinociceptive effect of morphine in diabetic mice.
Topics: Analgesics; Animals; Arginine; Blood Glucose; Body Weight; Camellia sinensis; Diabetes Mellitus, Experimental; Drug Interactions; Enzyme Inhibitors; Male; Mice; Morphine; NG-Nitroarginine Methyl Ester; Nitrites; Pain Threshold; Plant Extracts; Streptozocin | 2005 |
An association between plasma asymmetric dimethylarginine and membrane fluidity of erythrocytes in hypertensive and normotensive men: an electron paramagnetic resonance investigation.
Topics: Arginine; Electron Spin Resonance Spectroscopy; Erythrocyte Membrane; Humans; Hypertension; Male; Membrane Fluidity; Middle Aged; Nitrates; Nitrites | 2005 |
The role of nitric oxide in the modulation of hepatic microcirculation and tissue oxygenation in an experimental model of hepatic steatosis.
Topics: Alanine Transaminase; Animals; Arginine; Aspartate Aminotransferases; Cholesterol; Electron Transport Complex IV; Fatty Liver; Hemoglobins; Lipid Metabolism; Lipids; Liver; Male; Microcirculation; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitrites; Oxidation-Reduction; Oxygen; Oxyhemoglobins; Rats; Rats, Sprague-Dawley; Time Factors; Triglycerides | 2005 |
Therapeutic treatment with L-arginine rescues mice from heat stroke-induced death: physiological and molecular mechanisms.
Topics: Amino Acids, Essential; Animals; Apoptosis; Arginine; Blotting, Western; Caspase 3; Caspases; Cell Death; Cells, Cultured; Cytokines; DNA Fragmentation; Dose-Response Relationship, Drug; Down-Regulation; Electrophoresis, Polyacrylamide Gel; Heart; Heat Stroke; Hot Temperature; HSP70 Heat-Shock Proteins; Hyperthermia, Induced; Liver; Mice; Myocardium; Nitric Oxide; Nitrites; Proteins; Receptor, Bradykinin B1; RNA, Messenger; Spleen; Time Factors; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53; Up-Regulation | 2005 |
Influence of oxygen, temperature and carbon dioxide on nitric oxide formation from nitrite as measured in expired gas from in situ perfused rabbit lungs.
Topics: Animals; Arginine; Carbon Dioxide; Enzyme Inhibitors; In Vitro Techniques; Lung; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Oxygen; Perfusion; Rabbits; Temperature | 2005 |
Vascular and renal effects of dopamine during extracellular volume expansion: Role of nitric oxide pathway.
Topics: Animals; Aorta; Arginine; Blood Pressure; Citrulline; Diuresis; Dopamine; Dopamine Antagonists; Extracellular Fluid; Haloperidol; Kidney; Male; NADPH Dehydrogenase; Natriuresis; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Wistar; Renal Artery; Renal Plasma Flow | 2006 |
Hemodynamic effects of combined sildenafil and L-arginine during acute pulmonary embolism-induced pulmonary hypertension.
Topics: Acute Disease; Analysis of Variance; Animals; Arginine; Blood Pressure; Cyclic GMP; Dogs; Female; Heart Rate; Hypertension, Pulmonary; Infusions, Intravenous; Male; Nitrates; Nitrites; Piperazines; Pulmonary Artery; Pulmonary Embolism; Purines; Respiration; Sildenafil Citrate; Sulfones; Time Factors; Vasodilator Agents | 2005 |
Increased nitric oxide (NO) pathway metabolites in the vitreous fluid of patients with rhegmatogenous retinal detachment or diabetic traction retinal detachment.
Topics: Aged; Arginine; Chromatography, High Pressure Liquid; Citrulline; Diabetic Retinopathy; Female; Humans; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; Retinal Detachment; Signal Transduction; Vitreous Body | 2006 |
Beneficial effects of concurrent autologous bone marrow cell therapy and metabolic intervention in ischemia-induced angiogenesis in the mouse hindlimb.
Topics: Animals; Antioxidants; Arginine; Bone Marrow Transplantation; Disease Models, Animal; Fluorescent Antibody Technique; Hindlimb; Ischemia; Mice; Neovascularization, Pathologic; Nitrates; Nitrites; Oxidative Stress; Transplantation, Autologous | 2005 |
Nitric oxide and its modulators in chronic constriction injury-induced neuropathic pain in rats.
Topics: Animals; Arginine; Behavior, Animal; Cold Temperature; Constriction, Pathologic; Disease Models, Animal; Hindlimb; Hot Temperature; Hyperalgesia; Injections, Intraperitoneal; Injections, Intraventricular; Male; Neuralgia; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrites; Nitroprusside; Pain Threshold; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Sciatic Nerve; Stress, Mechanical | 2006 |
Blood cell NO synthesis in response to exercise.
Topics: Adult; Arginase; Arginine; Bicycling; Citrulline; Erythrocytes; Exercise; Humans; Lymphocytes; Male; Neutrophils; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Ornithine; Superoxide Dismutase | 2006 |
Abnormal nitric oxide metabolism in systemic sclerosis: increased levels of nitrated proteins and asymmetric dimethylarginine.
Topics: Adult; Arginine; Cells, Cultured; Endothelium, Vascular; Enzyme Inhibitors; Female; Humans; Male; Middle Aged; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Raynaud Disease; Scleroderma, Diffuse; Scleroderma, Limited; Scleroderma, Systemic; Severity of Illness Index | 2006 |
In vitro and in vivo effects of mercuric chloride on thymic endocrine activity, NK and NKT cell cytotoxicity, cytokine profiles (IL-2, IFN-gamma, IL-6): role of the nitric oxide-L-arginine pathway.
Topics: Animals; Arginine; Cells, Cultured; Cytokines; Cytotoxicity, Immunologic; Interferon-gamma; Interleukin-2; Killer Cells, Natural; Kinetics; Male; Mercuric Chloride; Mice; Mice, Inbred BALB C; Nitrates; Nitric Oxide; Nitrites; Organ Culture Techniques; Signal Transduction; Spleen; T-Lymphocytes; Thymic Factor, Circulating; Thymus Gland | 2006 |
Reduction of myocardial infarct size by tetrahydrobiopterin: possible involvement of mitochondrial KATP channels activation through nitric oxide production.
Topics: Animals; Anti-Arrhythmia Agents; Arginine; Biopterins; Cyclic GMP; Decanoic Acids; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydroxy Acids; Male; Malondialdehyde; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitrites; Potassium Channels; Rats; Rats, Sprague-Dawley | 2006 |
Real-time monitoring of nitric oxide and blood flow during ischemia-reperfusion in the rat testis.
Topics: Animals; Arginine; Blood Flow Velocity; Enzyme Inhibitors; Laser-Doppler Flowmetry; Male; Malondialdehyde; Monitoring, Physiologic; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Testis; Time Factors | 2006 |
Discriminating formation of HNO from other reactive nitrogen oxide species.
Topics: Arginine; Dimerization; Glutathione; Hydroxylamine; Nitrites; Nitrogen Dioxide; Nitrogen Oxides; Peroxynitrous Acid; Reactive Nitrogen Species | 2006 |
Involvement of nitric oxide in anti-tumor effects of OK-432, a streptococcal anti-tumor immunotherapeutic agent.
Topics: Animals; Antineoplastic Agents; Arginine; Cell Line, Tumor; Cell Survival; Female; Gene Expression Regulation; Immunization; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; Picibanil; RNA, Messenger; Spleen; Streptococcus pyogenes | 2006 |
Nitric oxide effect on the hemoglobin-oxygen affinity.
Topics: Animals; Arginine; Cells, Cultured; Erythrocytes; Hemoglobins; Hydrogen-Ion Concentration; Methemoglobin; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrites; Oxygen; Oxyhemoglobins; Protein Binding; Rabbits | 2006 |
Asymmetric dimethylarginine in homocystinuria due to cystathionine beta-synthase deficiency: relevance of renal function.
Topics: Adult; Arginine; Creatinine; Cystathionine beta-Synthase; Cystatin C; Cystatins; Female; Homocysteine; Homocystinuria; Humans; Kidney; Male; Middle Aged; Nitrates; Nitrites; Pyridoxine; Renal Insufficiency | 2006 |
Infected chronic wounds show different local and systemic arginine conversion compared with acute wounds.
Topics: Acute Disease; Adult; Amino Acids; Arginase; Arginine; Body Fluids; Chronic Disease; Citrulline; Female; Humans; Male; Middle Aged; Nitrates; Nitrites; Ornithine; Prospective Studies; Wound Healing; Wound Infection; Wounds and Injuries | 2006 |
Chronic inhibition of nitric oxide production aggravates diabetic nephropathy in Otsuka Long-Evans Tokushima Fatty rats.
Topics: Animals; Arginine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Enzyme Inhibitors; Kidney Glomerulus; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Proteinuria; Rats; Rats, Inbred OLETF; Time Factors | 2006 |
Attenuation of morphine tolerance and dependence by aminoguanidine in mice.
Topics: Analgesics; Analgesics, Opioid; Animals; Arginine; Behavior, Animal; Brain; Dizocilpine Maleate; Drug Tolerance; Enzyme Inhibitors; Glutamates; Guanidines; Male; Mice; Morphine; Morphine Dependence; Naloxone; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitrites; Pain; Pain Measurement; Time Factors | 2006 |
Arginine metabolic pathways determine its therapeutic benefit in experimental heatstroke: role of Th1/Th2 cytokine balance.
Topics: Animals; Antibodies; Arginine; Corticosterone; Cytokines; Dexamethasone; Heat Stroke; Liver; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Nitrites; Th1 Cells; Th2 Cells; Transforming Growth Factor beta | 2006 |
NO donors inhibit Na,K-ATPase activity by a protein kinase G-dependent mechanism in the nonpigmented ciliary epithelium of the porcine eye.
Topics: Animals; Aqueous Humor; Arginine; Ciliary Body; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitrites; Peroxynitrous Acid; Sodium-Potassium-Exchanging ATPase; Swine | 2006 |
Relationship between protective effects of rosiglitazone on endothelium and endogenous nitric oxide synthase inhibitor in streptozotocin-induced diabetic rats and cultured endothelial cells.
Topics: Acetylcholine; Animals; Aorta; Arginine; Cells, Cultured; Diabetes Mellitus, Experimental; Endothelium, Vascular; Hypoglycemic Agents; Intercellular Adhesion Molecule-1; Male; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide Synthase; Nitrites; Rats; Rats, Sprague-Dawley; Rosiglitazone; Thiazolidinediones; Tumor Necrosis Factor-alpha; Vasodilation | 2007 |
In vivo arginine production and intravascular nitric oxide synthesis in hypotensive sepsis.
Topics: Adult; Aged; Arginine; Case-Control Studies; Critical Illness; Female; Glomerular Filtration Rate; Humans; Hypotension; Male; Middle Aged; Nitrates; Nitric Oxide; Nitrites; Nitrogen Isotopes; Shock, Septic | 2006 |
L-arginine improves endothelial and myocardial function after brain death.
Topics: Animals; Arginine; Brain Death; Coronary Circulation; Dogs; Endothelium, Vascular; Heart; Hemodynamics; Myocardial Contraction; Myocardium; Nitrates; Nitric Oxide; Nitrites; Nitroprusside; Vasoconstriction; Vasodilator Agents | 2006 |
Galactosyl derivatives of L-arginine and D-arginine: synthesis, stability, cell permeation, and nitric oxide production in pituitary GH3 cells.
Topics: Animals; Arginine; Cattle; Cell Line, Tumor; Cell Membrane Permeability; Cells, Cultured; Chromatography, High Pressure Liquid; Endothelial Cells; Endothelium, Vascular; Galactose; Nitric Oxide; Nitrites; Pituitary Gland; Prodrugs; Rats; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Structure-Activity Relationship | 2006 |
Evidence for nitrite reductase activity in intact mouse Leydig tumor cells.
Topics: Animals; Arginine; Buffers; Cell Line, Tumor; Cyclic AMP; Electron Transport; Enzyme Inhibitors; Humans; Leydig Cell Tumor; Lipopolysaccharides; Male; Mice; Mice, Inbred BALB C; Nitrates; Nitric Oxide Synthase; Nitrite Reductases; Nitrites; Testicular Neoplasms; Testosterone | 2006 |
Salt loading on plasma asymmetrical dimethylarginine and the protective role of potassium supplement in normotensive salt-sensitive asians.
Topics: Adult; Arginine; Asian People; Blood Pressure; Dose-Response Relationship, Drug; Drug Resistance; Female; Humans; Male; Middle Aged; Nitrates; Nitric Oxide; Nitrites; Osmolar Concentration; Potassium, Dietary; Reference Values; Sodium Chloride, Dietary | 2006 |
Liver I/R injury is improved by the arginase inhibitor, N(omega)-hydroxy-nor-L-arginine (nor-NOHA).
Topics: Alanine Transaminase; Animals; Arginase; Arginine; Aspartate Aminotransferases; Biogenic Polyamines; Liver; Liver Transplantation; Male; Nitrates; Nitric Oxide; Nitrites; Ornithine; Putrescine; Rats; Rats, Inbred Lew; Reperfusion Injury; Spermidine; Spermine | 2007 |
Effects of beta-lactam antibiotics and L-arginine in the treatment of experimental sepsis in rats.
Topics: Animals; Arginine; Ascitic Fluid; Aztreonam; beta-Lactams; Ceftriaxone; Drug Therapy, Combination; Interleukin-10; Interleukin-1beta; Male; Nitrates; Nitrites; Rats; Rats, Wistar; Sepsis; Survival Analysis; Treatment Outcome; Tumor Necrosis Factor-alpha | 2006 |
Evaluation of a urinary multi-parameter biomarker set for oxidative stress in children, adolescents and young adults.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acrolein; Adolescent; Adult; Arginine; Biomarkers; Child; Child, Preschool; Deoxyguanosine; Female; Glycation End Products, Advanced; Humans; Infant; Lysine; Male; Nitrates; Nitric Oxide; Nitrites; Oxidative Stress; Reactive Oxygen Species | 2006 |
Arginine supplementation induces myoblast fusion via augmentation of nitric oxide production.
Topics: Animals; Arginine; Calcium Channels; Cell Differentiation; Cell Line; Histocytochemistry; Membrane Fusion; Mice; Myoblasts, Skeletal; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitrites; RNA, Messenger; Time Factors; TRPV Cation Channels | 2006 |
Vaso-occlusion in Schimke-immuno-osseous dysplasia: is the NO pathway involved?
Topics: Adolescent; Adult; Arginine; Arterial Occlusive Diseases; Atherosclerosis; Child; Child, Preschool; Female; Glomerulosclerosis, Focal Segmental; Humans; Male; Nephrotic Syndrome; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Osteochondrodysplasias | 2006 |
Low nitric oxide bioavailability contributes to the genesis of experimental cerebral malaria.
Topics: Alkenes; Animals; Arginine; Blood Pressure; Capillary Permeability; Cyclic GMP; Hemoglobins; Malaria, Cerebral; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Animal; Models, Biological; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; Plasmodium berghei; Tissue Distribution | 2006 |
Asymmetric dimethylarginine induces oxidative and nitrosative stress in murine lung epithelial cells.
Topics: Animals; Arginine; Cell Line; Epithelial Cells; Ethidium; Fluorescence; Interferon-gamma; Lipopolysaccharides; Lung; Mice; Models, Biological; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; Nitrosation; Oxidation-Reduction; Oxidative Stress; Peroxynitrous Acid; Rhodamines; Superoxides; Tumor Necrosis Factor-alpha | 2007 |
Effects of acute and chronic L-arginine treatment in experimental hyperuricemia.
Topics: Animals; Arginine; Arterioles; Endothelium, Vascular; Hypertension; Hyperuricemia; Kidney Glomerulus; Male; Nitrates; Nitrites; Oxonic Acid; Rats; Rats, Sprague-Dawley | 2007 |
[Effect of puerarin on ADMA-DDAH system in human umbilical vein endothelial cells cultured with oxidized free radical].
Topics: Amidohydrolases; Arginine; Blotting, Western; Cells, Cultured; Culture Media; Endothelial Cells; Endothelins; Free Radicals; Humans; Isoflavones; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Oxidation-Reduction; Umbilical Veins | 2006 |
Effect of nitric oxide on phagocytic activity of lipopolysaccharide-induced macrophages: possible role of exogenous L-arginine.
Topics: Animals; Arginine; Guanidines; Lipopolysaccharides; Macrophages, Peritoneal; Male; Nitric Oxide; Nitrites; Phagocytosis; Rats; Rats, Wistar | 2007 |
Asymmetric dimethylarginine (ADMA) induces vascular endothelium impairment and aggravates post-ischemic ventricular dysfunction in rats.
Topics: Acetylcholine; Angiotensin II; Animals; Aorta; Arginine; Blood Pressure; Endothelium, Vascular; Enzyme Inhibitors; Heart Rate; Male; Myocardial Reperfusion Injury; Nitrates; Nitrites; Perfusion; Rats; Rats, Wistar; RNA, Messenger; Vasoconstrictor Agents; Vasodilator Agents; Ventricular Dysfunction | 2007 |
Synergistic therapeutic potential of dexamethasone and L-arginine in lipopolysaccharide-induced septic shock.
Topics: Alanine Transaminase; Animals; Arginase; Arginine; Aspartate Aminotransferases; Cytokines; Dexamethasone; Disease Models, Animal; Drug Synergism; Glucocorticoids; HSP70 Heat-Shock Proteins; Lipopolysaccharides; Liver; Male; Mice; Mice, Inbred Strains; Nitric Oxide Synthase Type II; Nitrites; Shock, Septic; Survival Rate | 2007 |
Asymmetric dimethylarginine (ADMA) in the aqueous humor of diabetic patients.
Topics: Aged; Aqueous Humor; Arginine; Cataract; Cataract Extraction; Diabetes Complications; Diabetes Mellitus; Female; Glycated Hemoglobin; Humans; Male; Middle Aged; Nitrates; Nitrites | 2007 |
Determination of cerebrospinal fluid concentrations of arginine and dimethylarginines in patients with subarachnoid haemorrhage.
Topics: Adult; Aged; Aged, 80 and over; Arginine; Brain; Cerebrospinal Fluid; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Middle Aged; Neurochemistry; Nitrates; Nitric Oxide; Nitrites; Subarachnoid Hemorrhage; Up-Regulation | 2007 |
Receptor-mediated activation of nitric oxide synthesis by arginine in endothelial cells.
Topics: Adrenergic alpha-Antagonists; Agmatine; Aniline Compounds; Arginine; Calcium; Calcium Channel Blockers; Cell Culture Techniques; Cells, Cultured; Culture Media, Serum-Free; Dexmedetomidine; Dose-Response Relationship, Drug; Endothelial Cells; Endothelium, Vascular; Enzyme Activation; Estrenes; Fluorescent Dyes; Humans; Idazoxan; Imidazolines; Lipopolysaccharides; Molecular Structure; NG-Nitroarginine Methyl Ester; Nifedipine; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; Pyrrolidinones; Receptors, Adrenergic, alpha-2; Second Messenger Systems; Type C Phospholipases; Umbilical Veins; Virulence Factors, Bordetella; Xanthenes; Yohimbine | 2007 |
Delayed 24 hours Nomega-nitro-L-arginine methyl ester injection induces pharmacological cardioprotection against reperfusion injury.
Topics: Adenosine; Animals; Arginine; Blood Pressure; Cardiotonic Agents; Disease Models, Animal; Enzyme Inhibitors; Myocardial Ischemia; Myocardial Reperfusion Injury; Nitrates; Nitric Oxide Synthase; Nitrites; Perfusion; Rats; Regional Blood Flow; Theophylline; Time Factors; Troponin I; Ventricular Function, Left | 2007 |
Role of asymmetric dimethylarginine in inflammatory reactions by angiotensin II.
Topics: Amidohydrolases; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Arginine; Cell Adhesion; Cells, Cultured; Culture Media, Conditioned; Endothelial Cells; Endothelium, Vascular; Gene Expression Regulation; Humans; Interleukin-8; Losartan; Monocytes; NF-kappa B; Nitrates; Nitric Oxide; Nitrites; Protein-Arginine N-Methyltransferases; Reactive Oxygen Species; Receptors, Interleukin-8B; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha; Umbilical Veins; Vasculitis; Vasodilation | 2007 |
L-arginine attenuates acute lung injury after smoke inhalation and burn injury in sheep.
Topics: Airway Obstruction; Animals; Arginine; Blood Pressure; Burns; Female; Hematocrit; Lung; Lung Injury; Nitrates; Nitrites; Random Allocation; Sheep; Smoke Inhalation Injury; Survival Analysis; Tyrosine; Urination | 2007 |
Pressure-related increase of asymmetric dimethylarginine caused by hyperbaric oxygen in the rat brain: a possible neuroprotective mechanism.
Topics: Animals; Arginine; Brain; Hyperbaric Oxygenation; Male; Nitrates; Nitrites; Rats; Rats, Sprague-Dawley | 2007 |
The role of nitric oxide in diabetes-induced changes of morphine tolerance in rats.
Topics: Analgesics, Opioid; Animals; Arginine; Diabetes Mellitus, Experimental; Drug Tolerance; Guanidines; Hot Temperature; Male; Morphine; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; Pain; Rats; Rats, Sprague-Dawley | 2007 |
Twenty-four-hour variation of L-arginine/nitric oxide/cyclic guanosine monophosphate pathway demonstrated by the mouse visceral pain model.
Topics: Abdominal Pain; Analgesics; Animals; Arginine; Benzoquinones; Circadian Rhythm; Cyclic GMP; Enzyme Inhibitors; Male; Methylene Blue; Mice; Mice, Inbred Strains; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitrites; Nitroprusside; Pain; Pain Measurement; Signal Transduction | 2007 |
GC-MS assay for hepatic DDAH activity in diabetic and non-diabetic rats by measuring dimethylamine (DMA) formed from asymmetric dimethylarginine (ADMA): evaluation of the importance of S-nitrosothiols as inhibitors of DDAH activity in vitro and in vivo in
Topics: Amidohydrolases; Animals; Arginine; Catalysis; Diabetes Mellitus, Experimental; Dimethylamines; Enzyme Inhibitors; Female; Gas Chromatography-Mass Spectrometry; Humans; Kinetics; Liver; Male; Molecular Structure; Nitrates; Nitrites; Rats; Rats, Wistar; Reproducibility of Results; S-Nitrosothiols | 2007 |
Arginine flux and intravascular nitric oxide synthesis in severe childhood undernutrition.
Topics: Arginine; Case-Control Studies; Edema; Female; Humans; Infant; Infant Nutrition Disorders; Infections; Kwashiorkor; Male; Nitrates; Nitric Oxide; Nitrites; Nitrogen Isotopes; Protein-Energy Malnutrition | 2007 |
11,12-Epoxyeicosatrienoic acid activates the L-arginine/nitric oxide pathway in human platelets.
Topics: 8,11,14-Eicosatrienoic Acid; Adult; Arginine; Biological Transport; Blood Platelets; Calcium Signaling; Collagen; Cyclic GMP; Female; Humans; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Tritium | 2008 |
Association of an endogenous inhibitor of nitric oxide synthase with cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage.
Topics: Adult; Aged; Arginine; Arnold-Chiari Malformation; Citrulline; Enzyme Inhibitors; Female; Humans; Intracranial Aneurysm; Male; Middle Aged; Nitric Oxide Synthase; Nitrites; Subarachnoid Hemorrhage; Vasospasm, Intracranial | 2007 |
Nitric oxide in flow-through venous flaps and effects of L-arginine and nitro-L-arginine methyl ester (L-NAME) on nitric oxide and flap survival in rabbits.
Topics: Animals; Arginine; Enzyme Inhibitors; Graft Survival; Male; Models, Biological; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Rabbits; Skin Transplantation; Surgical Flaps; Veins | 2007 |
The effects of arginine and selective inducible nitric oxide synthase inhibitor on pathophysiology of sepsis in a CLP model.
Topics: Animals; Arginine; Disease Models, Animal; Drug Therapy, Combination; Enzyme Inhibitors; Guanidines; Heme Oxygenase-1; Male; Nitrates; Nitric Oxide Synthase; Nitrites; Oxidative Stress; Rats; Rats, Sprague-Dawley; Sepsis | 2008 |
Therapeutic concentrations of tacrolimus do not interfere with endothelial nitric oxide synthesis in rat thoracic aortas and coronary arteries.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Calcimycin; Cells, Cultured; Coronary Vessels; Endothelial Cells; Immunosuppressive Agents; In Vitro Techniques; Interleukin-1beta; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Nitroprusside; Phenylephrine; Potassium Chloride; Rats; Rats, Wistar; Tacrolimus; Vasoconstriction; Vasodilation | 2007 |
Effects of l-arginine and N(G)-nitro-l-arginine methyl ester treatments on expression of neuronal nitric oxide synthase in the guinea-pig bladder after partial bladder outlet obstruction.
Topics: Analysis of Variance; Animals; Arginine; Cell Count; Colorimetry; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Guinea Pigs; Male; Microscopy, Electron, Transmission; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase Type I; Nitrites; Time Factors; Urinary Bladder; Urinary Bladder Neck Obstruction | 2008 |
Determination of asymmetric dimethylarginine, an endogenous nitric oxide synthase inhibitor, in umbilical blood.
Topics: Adolescent; Adult; Arginine; Child; Child, Preschool; Enzyme Inhibitors; Female; Fetal Blood; Humans; Infant, Newborn; Infant, Premature; Linear Models; Male; Middle Aged; Nitrates; Nitric Oxide Synthase Type III; Nitrites; Pregnancy; Umbilical Veins | 2008 |
Cytoprotective role of nitric oxide associated with Hsp70 expression in neonatal obstructive nephropathy.
Topics: Animals; Animals, Newborn; Apoptosis; Arginine; bcl-2-Associated X Protein; Body Weight; Caspase 3; Cytoprotection; Disease Models, Animal; Female; HSP70 Heat-Shock Proteins; Immunoprecipitation; Kidney; Kidney Diseases; Male; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; Organ Size; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Superoxide Dismutase; Ureteral Obstruction | 2008 |
L-arginine uptake in normal and diabetic rat retina and retinal pigment epithelium.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Nitrates; Nitric Oxide; Nitrites; Pigment Epithelium of Eye; Rats; Rats, Long-Evans; Retina | 2008 |
Measurement of NO and NO synthase.
Topics: Animals; Arginine; Citrulline; Colorimetry; Ethylenediamines; Luminescent Measurements; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Oxidation-Reduction; Sulfanilamides | 2001 |
Possible nitric oxide modulation in protective effect of (Curcuma longa, Zingiberaceae) against sleep deprivation-induced behavioral alterations and oxidative damage in mice.
Topics: Animals; Anxiety; Arginine; Behavior, Animal; Body Weight; Catalase; Curcumin; Dose-Response Relationship, Drug; Lipid Peroxidation; Male; Mice; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Oxidative Stress; Phytotherapy; Sleep Deprivation | 2008 |
Age related differences in stress-induced neurobehavioral responses in rats: modulation by antioxidants and nitrergic agents.
Topics: Aging; alpha-Tocopherol; Animals; Antioxidants; Arginine; Behavior, Animal; Catalase; Enzyme Inhibitors; Exploratory Behavior; Lipid Peroxidation; Male; Malondialdehyde; Maze Learning; NG-Nitroarginine Methyl Ester; Nitrates; Nitrites; Rats; Rats, Wistar; Restraint, Physical; Stress, Psychological; Superoxide Dismutase | 2008 |
Lateralization of hippocampal nitric oxide mediator system in people with Alzheimer disease, multi-infarct dementia and schizophrenia.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Arginine; Citrulline; Dementia, Multi-Infarct; Female; Functional Laterality; Glutamine; Hippocampus; Humans; Isoenzymes; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Schizophrenia; Signal Transduction | 2008 |
The prevention of endothelial dysfunction through endothelial cell apoptosis inhibition in a hypercholesterolemic rabbit model: the effect of L-arginine supplementation.
Topics: Animals; Aorta; Apoptosis; Arginine; Atherosclerosis; Cell Count; Cholesterol; Dietary Supplements; Disease Models, Animal; Endothelial Cells; Hypercholesterolemia; In Situ Nick-End Labeling; Male; Nitrites; Rabbits | 2008 |
Nitric oxide synthase isoforms and NF-kappaB activity in normal and osteoarthritic human chondrocytes: regulation by inducible nitric oxide.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arginine; Blotting, Western; Chondrocytes; Electrophoretic Mobility Shift Assay; Gene Expression Regulation; Humans; I-kappa B Proteins; Interleukin-1beta; Isoenzymes; Middle Aged; NF-kappa B; NF-KappaB Inhibitor alpha; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitrites; Osteoarthritis, Knee | 2008 |
L-arginine supplementation influenced nitrite but not nitrate and total nitrite in rabbit model of hypercholesterolemia.
Topics: Animals; Arginine; Cholesterol; Dietary Supplements; Disease Models, Animal; Hypercholesterolemia; Male; Nitrates; Nitrites; Rabbits | 2008 |
Differences in nitric oxide steady states between arginine, hypoxanthine, uracil auxotrophs (AHU) and non-AHU strains of Neisseria gonorrhoeae during anaerobic respiration in the presence of nitrite.
Topics: Anaerobiosis; Arginine; Autotrophic Processes; Bacterial Proteins; Female; Gonorrhea; Humans; Hypoxanthine; Male; Neisseria gonorrhoeae; Nitric Oxide; Nitrite Reductases; Nitrites; Oxidoreductases; Uracil | 2008 |
The role of nitric oxide on the proliferation of a human osteoblast cell line stimulated with hydroxyapatite.
Topics: Antibodies; Arginine; Benzoates; Biocompatible Materials; Cell Line; Cell Proliferation; Cells, Cultured; Durapatite; Enzyme Inhibitors; Humans; Imidazoles; Integrin alphaV; Lysine; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Ornithine; Osteoblasts | 2008 |
Biomarkers of oxidative stress and endothelial dysfunction in glucose intolerance and diabetes mellitus.
Topics: Arginine; Biomarkers; Body Mass Index; Diabetes Mellitus, Type 2; Endothelium; Female; Glucose Intolerance; Glutathione; Hexosaminidases; Humans; Lipids; Male; Middle Aged; Nitrates; Nitric Oxide; Nitrites; Oxidative Stress | 2008 |
Mechanisms underlying erythrocyte and endothelial nitrite reduction to nitric oxide in hypoxia: role for xanthine oxidoreductase and endothelial nitric oxide synthase.
Topics: Allopurinol; Animals; Aorta; Arginine; Cell Hypoxia; Cells, Cultured; Endothelial Cells; Enzyme Inhibitors; Erythrocytes; Fluorometry; Humans; Hydrogen-Ion Concentration; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrite Reductases; Nitrites; omega-N-Methylarginine; Oxidation-Reduction; Rats; Rats, Wistar; Xanthine; Xanthine Dehydrogenase | 2008 |
The L-arginine/NO pathway in end-stage liver disease and during orthotopic liver and kidney transplantation: biological and analytical ramifications.
Topics: Adult; Aged; Amidohydrolases; Arginine; Dimethylamines; Female; Gas Chromatography-Mass Spectrometry; Humans; Hydrolases; Kidney; Kidney Transplantation; Liver; Liver Diseases; Liver Transplantation; Male; Middle Aged; Nitrates; Nitric Oxide; Nitrites; Ornithine; Peptide Hydrolases; Tandem Mass Spectrometry | 2009 |
Nitric oxide production in the exhaled air of patients with pulmonary tuberculosis in relation to HIV co-infection.
Topics: Adolescent; Adult; Arginine; Blood Donors; Cross-Sectional Studies; Ethiopia; Exhalation; Female; HIV Infections; Humans; Interleukin-12; Lung; Male; Nitrates; Nitric Oxide; Nitrites; Tuberculosis, Pulmonary; Tumor Necrosis Factor-alpha; Young Adult | 2008 |
Nitric oxide production and monoamine oxidase activity in cancer patients during interferon-alpha therapy.
Topics: Adult; Aged; Arginine; Blood Platelets; Carcinoma, Renal Cell; Citrulline; Female; Humans; Interferon-alpha; Kidney Neoplasms; Male; Melanoma; Middle Aged; Monoamine Oxidase; Nitrates; Nitric Oxide; Nitrites; Prospective Studies; Skin Neoplasms | 2009 |
Exogenous L-arginine ameliorates angiotensin II-induced hypertension and renal damage in rats.
Topics: Albuminuria; Angiotensin II; Animals; Arginine; Blood Pressure; Consciousness; Creatinine; Drug Interactions; Glomerular Filtration Rate; Hypertension, Renal; Kidney Glomerulus; Male; Nitrates; Nitric Oxide; Nitrites; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents | 2008 |
Carotid intima-media thickness in patients with cardiac syndrome X and its association with high circulating levels of asymmetric dimethylarginine.
Topics: Adult; Arginine; Carotid Artery Diseases; Carotid Artery, Common; Case-Control Studies; Female; Humans; Male; Microvascular Angina; Middle Aged; Nitrates; Nitrites; Tunica Intima; Tunica Media; Ultrasonography; Up-Regulation | 2009 |
A role for nitrergic system in the antidepressant-like effects of chronic lithium treatment in the mouse forced swimming test.
Topics: Analysis of Variance; Animals; Antimanic Agents; Arginine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Exploratory Behavior; Freezing Reaction, Cataleptic; Lithium Chloride; Male; Mice; Mice, Inbred Strains; Motor Activity; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitrites; Swimming | 2009 |
Asymmetric dimethylarginine and nitric oxide levels in migraine during the interictal period.
Topics: Adult; Arginine; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Middle Aged; Migraine Disorders; Nitrates; Nitric Oxide; Nitrites; Statistics, Nonparametric | 2009 |
Response of blood vessels in vitro to hyperbaric oxygen (HBO): modulation of VEGF and NO(x) release by external lactate or arginine.
Topics: Animals; Aorta; Arginine; Glutathione; Hyperbaric Oxygenation; L-Lactate Dehydrogenase; Male; Nitrates; Nitric Oxide; Nitrites; Organ Culture Techniques; Oxygen; Random Allocation; Rats; Rats, Sprague-Dawley; Time Factors; Vascular Endothelial Growth Factor A | 2009 |
Nebivolol decreases endothelial cell stiffness via the estrogen receptor beta: a nano-imaging study.
Topics: Adenocarcinoma; Adrenergic beta-Antagonists; Antihypertensive Agents; Arginine; Benzopyrans; Breast Neoplasms; Cell Line; Cell Line, Tumor; Cell Size; Dose-Response Relationship, Drug; Drug Combinations; Elasticity; Endothelial Cells; Estradiol; Estrogen Antagonists; Estrogen Receptor beta; Estrogen Receptor Modulators; Estrogens; Ethanolamines; Female; Fulvestrant; Genes, Reporter; Humans; Metoprolol; Nanotechnology; Nebivolol; Nitric Oxide; Nitrites; Tamoxifen; Time Factors; Transfection | 2009 |
Elevation of serum apelin-13 is positively correlated with ADMA in patients on maintenance hemodialysis.
Topics: Adult; Aged; Aged, 80 and over; Arginine; Biomarkers; Female; Humans; Intercellular Signaling Peptides and Proteins; Kidney Failure, Chronic; Male; Middle Aged; Nitrates; Nitrites; Renal Dialysis; Time Factors | 2009 |
Increased nitric oxide formation followed by increased arginase activity induces relative lack of arginine at the wound site and alters whole nutritional status in rats almost within the early healing period.
Topics: Amino Acids; Animals; Arginase; Arginine; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; Nutritional Status; Rats; Rats, Inbred Strains; Urea; Wound Healing | 2009 |
The gastric ulcer-healing action of allylpyrocatechol is mediated by modulation of arginase metabolism and shift of cytokine balance.
Topics: Animals; Anti-Inflammatory Agents; Arginase; Arginine; Catechols; Cytokines; Gene Expression Regulation, Enzymologic; Male; Mice; Mucous Membrane; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Peroxidase; Stomach Ulcer | 2009 |
High glucose-induced changes in steroid production in adrenal cells.
Topics: Analysis of Variance; Animals; Arginine; Cells, Cultured; Clone Cells; Dose-Response Relationship, Drug; Glucose; Heme Oxygenase (Decyclizing); Humans; Hyperglycemia; Mice; Nitrites; Oxidative Stress; Progesterone; Rats; Reactive Oxygen Species; Statistics, Nonparametric; Thiobarbituric Acid Reactive Substances; Transfection; Zona Fasciculata | 2009 |
Effect of a sulfonated azo dye and sulfanilic acid on nitrogen transformation processes in soil.
Topics: Aerobiosis; Analysis of Variance; Arginine; Azo Compounds; Coloring Agents; Hydrogen-Ion Concentration; Kinetics; Minerals; Naphthalenesulfonates; Nitrites; Nitrogen; Nitrogen Fixation; Oxidation-Reduction; Quaternary Ammonium Compounds; Soil; Soil Microbiology; Sulfanilic Acids; Urease | 2009 |
[Nitric oxide synthesis during long-term adaptation to intensive muscular work in female sportsmen].
Topics: Adaptation, Physiological; Adolescent; Adult; Arginine; Athletic Performance; Calcium; Female; Humans; Motor Activity; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Nitrites; Time Factors; Young Adult | 2009 |
Arginine is essential in reversing prostaglandin E(2) T-cell suppression by hypertonic saline.
Topics: Arginase; Arginine; Cell Proliferation; Dinoprostone; Humans; Jurkat Cells; Nitric Oxide Synthase Type II; Nitrites; Saline Solution, Hypertonic; T-Lymphocytes | 2009 |
Increased nitric oxide stress is associated with migraine.
Topics: Adult; Aged; Amidohydrolases; Arginine; Female; Humans; Male; Migraine with Aura; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Polymorphism, Genetic; Risk Factors; Stress, Physiological | 2010 |
Arginase inhibition mediates cardioprotection during ischaemia-reperfusion.
Topics: Amino Acids; Animals; Arginase; Arginine; Blood Pressure; Enzyme Inhibitors; Heart Rate; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Sprague-Dawley | 2010 |
L-arginine augments the antioxidant effect of garlic against acetic acid-induced ulcerative colitis in rats.
Topics: Acetic Acid; Animals; Antioxidants; Arginine; Catalase; Chemistry, Pharmaceutical; Colitis, Ulcerative; Colon; Drug Synergism; Garlic; Glutathione; Male; Nitrites; Organ Size; Plant Extracts; Rats; Rats, Wistar; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2009 |
Role of asymmetric-dimethyl-L-arginine (ADMA) and nitrite/nitrate (NOx) in the pathogenesis of oxidative stress in female subjects with uncomplicated type 1 diabetes mellitus.
Topics: Adult; Arginine; Blood Glucose; Blood Specimen Collection; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 1; Feeding Behavior; Female; Glycated Hemoglobin; Humans; Nitrates; Nitrites; Oxidative Stress; Reference Values; Uric Acid | 2009 |
Regulation of the ADMA-DDAH system in endothelial cells: a novel mechanism for the sterol response element binding proteins, SREBP1c and -2.
Topics: Amidohydrolases; Arginine; Blotting, Western; Cells, Cultured; Chromatin; Chromatography, High Pressure Liquid; DNA Primers; Endothelial Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunoprecipitation; Lentivirus; Nitrites; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Simvastatin; Sterol Regulatory Element Binding Protein 1; Sterol Regulatory Element Binding Protein 2; Transfection | 2010 |
Asymmetric dimethylarginine in angiotensin II-induced hypertension.
Topics: Amidohydrolases; Angiotensin II; Animals; Arginine; Blood Pressure; Fibrosis; Hypertension, Renal; Kidney Cortex; Male; NADPH Oxidases; Nitrates; Nitrites; Oxidative Stress; Protein-Arginine N-Methyltransferases; Rats; Rats, Sprague-Dawley; Thiobarbituric Acid Reactive Substances; Vasoconstrictor Agents | 2010 |
Metabotropic glutamate receptor 5, but not 1, modulates NMDA receptor-mediated activation of neuronal nitric oxide synthase.
Topics: Animals; Arginine; Blotting, Western; Calcium; Cells, Cultured; Cerebellum; Citrulline; Cyclic AMP; Cyclic GMP; Enzyme Activation; Excitatory Amino Acid Agonists; Guanylate Cyclase; N-Methylaspartate; Neurons; Nitrates; Nitric Oxide Synthase Type I; Nitrites; Oncogene Protein v-akt; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate | 2010 |
Impairment of human cell-based vasculogenesis in rats by hypercholesterolemia-induced endothelial dysfunction and rescue with L-arginine supplementation.
Topics: Animals; Arginine; Cytokines; Endothelial Cells; Endothelin-1; Extremities; Humans; Hypercholesterolemia; Neovascularization, Physiologic; Nitrites; Rats; Rats, Nude; Rats, Sprague-Dawley | 2010 |
L-arginine enhances nitrative stress and exacerbates tumor necrosis factor-alpha toxicity to human endothelial cells in culture: prevention by propofol.
Topics: Apoptosis; Arginine; Cell Line; Cell Survival; Endothelial Cells; Enzyme Inhibitors; Glutathione Peroxidase; Guanidines; Humans; Hydrogen Peroxide; L-Lactate Dehydrogenase; Malondialdehyde; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Nitroarginine; Oxidative Stress; Propofol; Superoxide Dismutase; Superoxides; Tumor Necrosis Factor-alpha; Tyrosine | 2010 |
Involvement of L-arginine-nitric oxide-cyclic guanosine monophosphate pathway in the antidepressant-like effect of bis selenide in the mouse tail suspension test.
Topics: Administration, Oral; Animals; Antidepressive Agents; Arginine; Behavior, Animal; Brain; Cyclic GMP; Hindlimb Suspension; Male; Mice; Nitrates; Nitric Oxide; Nitrites; Organoselenium Compounds; Signal Transduction; Swimming | 2010 |
Increased inducible nitric oxide synthase and arginase II expression in heart failure: no net nitrite/nitrate production and protein S-nitrosylation.
Topics: Animals; Arginase; Arginine; Blotting, Western; Cardiac Pacing, Artificial; Disease Models, Animal; Enzyme Inhibitors; Heart Failure; Heart Rate; Imines; Male; Microscopy, Confocal; Myocardial Contraction; Myocardium; Nitrates; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitrites; Protein Processing, Post-Translational; Rabbits; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stroke Volume; Superoxides; Up-Regulation; Ventricular Function, Left | 2010 |
Interethnic differences in ADMA concentrations and negative association with nitric oxide formation in preeclampsia.
Topics: Adult; Arginine; Biomarkers; Black People; Case-Control Studies; Ethnicity; Female; Humans; Nitric Oxide; Nitrites; Pre-Eclampsia; Pregnancy; White People; Young Adult | 2010 |
Involvement of nitric oxide in a rat model of carrageenin-induced pleurisy.
Topics: Animals; Antioxidants; Arginine; Carrageenan; Disease Models, Animal; Male; Malondialdehyde; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrites; Pleurisy; Rats; Rats, Wistar; Thiourea | 2010 |
Posttransplantation therapeutic rapamycin concentration protects nitric oxide-related vascular endothelial function: comparative effects in rat thoracic aorta and coronary endothelial cell culture.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Blotting, Western; Calcimycin; Cell Culture Techniques; Coronary Vessels; Endothelium, Vascular; Immunosuppressive Agents; Interleukin-1beta; Male; Nitrites; Phenylephrine; Rats; Rats, Wistar; Sirolimus; Vasodilation | 2010 |
Dimethylarginine metabolism during acute and chronic rejection of rat renal allografts.
Topics: Acute Disease; Animals; Arginine; Blotting, Western; Chronic Disease; Graft Rejection; Immunoenzyme Techniques; Kidney Diseases; Kidney Transplantation; Male; Nitrates; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Protein-Arginine N-Methyltransferases; Rats; Rats, Inbred Strains; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transplantation, Homologous | 2011 |
New insights into the mitochondrial nitric oxide production pathways.
Topics: Arginine; Hordeum; Luminescent Measurements; Mitochondria; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Oxidation-Reduction; Plant Roots | 2010 |
Asymmetric dimethylarginine potentiates lung inflammation in a mouse model of allergic asthma.
Topics: Amidohydrolases; Animals; Arginine; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Enzyme Inhibitors; Epithelial Cells; Humans; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Transgenic; Nitric Oxide Synthase Type II; Nitrites; Ovalbumin; Pneumonia; Respiratory Mucosa | 2010 |
Acute lung injury-induced collagen deposition is associated with elevated asymmetric dimethylarginine and arginase activity.
Topics: Acute Lung Injury; Amidohydrolases; Animals; Arginase; Arginine; Blotting, Western; Collagen; Female; Lipid Peroxidation; Nitrates; Nitrites; Sheep | 2011 |
Simvastatin inhibits goblet cell hyperplasia and lung arginase in a mouse model of allergic asthma: a novel treatment for airway remodeling?
Topics: Aerosols; Animals; Arginase; Arginine; Asthma; Blotting, Western; Coloring Agents; Disease Models, Animal; Goblet Cells; Hydroxyproline; Hyperplasia; Immunohistochemistry; Inflammation; Lung; Mice; Nitrates; Nitrites; Ovalbumin; Simvastatin; Transforming Growth Factor beta1 | 2010 |
Down syndrome patients with pulmonary hypertension have elevated plasma levels of asymmetric dimethylarginine.
Topics: Arginine; Biomarkers; Down Syndrome; Female; Humans; Hypertension, Pulmonary; Infant; Male; Nitrates; Nitrites | 2011 |
Cationic amino acid transporters and Salmonella Typhimurium ArgT collectively regulate arginine availability towards intracellular Salmonella growth.
Topics: Amino Acid Transport Systems, Basic; Animals; Arginine; Bacterial Proteins; Cells, Cultured; Cytosol; Genetic Complementation Test; Macrophages; Mice; Mice, Inbred BALB C; Mycobacterium bovis; Nitrites; Reverse Transcriptase Polymerase Chain Reaction; Salmonella Infections; Salmonella typhimurium; Virulence | 2010 |
Arginase inhibition restores in vivo coronary microvascular function in type 2 diabetic rats.
Topics: Amino Acids; Animals; Arginase; Arginine; Blood Flow Velocity; Blood Glucose; Coronary Circulation; Diabetes Mellitus, Type 2; Disease Models, Animal; Enzyme Inhibitors; Insulin; Male; Microvessels; Nitrites; omega-N-Methylarginine; Rats; Rats, Wistar | 2011 |
Asymmetric dimethylarginine and vascular indices of atherosclerosis in patients after coarctation of aorta repair.
Topics: Adult; Aortic Coarctation; Arginine; Atherosclerosis; Biomarkers; Blood Flow Velocity; C-Reactive Protein; Cardiac Surgical Procedures; Carotid Intima-Media Thickness; Female; Humans; Male; Nitrates; Nitrites; Postoperative Complications; Pulsatile Flow; Vascular Stiffness; Vasodilation | 2012 |
Involvement of vascular endothelial nitric oxide synthase in development of experimental diabetic nephropathy in rats.
Topics: Animals; Arginine; Blood Glucose; Blood Urea Nitrogen; Body Weight; Caveolin 1; Cholesterol; Collagen; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dietary Fats; Endothelium, Vascular; Isoflavones; Kidney; Male; Nitric Oxide Synthase Type III; Nitrites; Organ Size; Proteinuria; Rats; Rats, Wistar; Sodium Nitrite; Urine | 2011 |
Effects of oral administration of (L)-arginine, (L)-NAME and allopurinol on intestinal ischemia/reperfusion injury in rats.
Topics: Administration, Oral; Allopurinol; Animals; Arginine; Catalase; Intestines; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Nitrites; Peroxidase; Rats; Rats, Wistar; Reperfusion Injury; Time Factors; Tyrosine | 2011 |
A calcium-insensitive attenuated nitrosative stress response contributes significantly in the radioresistance of Sf9 insect cells.
Topics: Animals; Arginine; Calcium; Calcium Signaling; Calmodulin; Cell Line; Hemin; Humans; Insect Proteins; Lepidoptera; Membrane Potential, Mitochondrial; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Oxidative Stress; Radiation Tolerance; Reactive Nitrogen Species; Reactive Oxygen Species | 2011 |
High temperature triggers the metabolism of S-nitrosothiols in sunflower mediating a process of nitrosative stress which provokes the inhibition of ferredoxin-NADP reductase by tyrosine nitration.
Topics: Aldehyde Oxidoreductases; Arginine; Ferredoxin-NADP Reductase; Gene Expression Regulation, Plant; Helianthus; Hot Temperature; Hypocotyl; Lipid Peroxides; Nitrate Reductase; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitrosation; Peroxynitrous Acid; Photosynthesis; Proteomics; S-Nitrosoglutathione; S-Nitrosothiols; Stress, Physiological; Superoxides; Tyrosine | 2011 |
Nitric oxide synthase activity in the abdominal aorta of rats is decreased after 4 weeks of simulated microgravity.
Topics: Acetylcholine; Animals; Aorta, Abdominal; Arginine; Cyclic GMP; Male; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Nitroprusside; Rats; Rats, Sprague-Dawley; Time Factors; Vasodilation; Weightlessness Simulation | 2011 |
L-arginine is essential for pancreatic β-cell functional integrity, metabolism and defense from inflammatory challenge.
Topics: AMP-Activated Protein Kinase Kinases; Animals; Arginine; Cell Line; Cell Survival; Cells, Cultured; Cytokines; Dose-Response Relationship, Drug; Glutamic Acid; Glutathione; Glutathione Disulfide; HSP72 Heat-Shock Proteins; Inflammation; Insulin; Insulin Secretion; Insulin-Secreting Cells; Islets of Langerhans; Models, Animal; Nitric Oxide Synthase Type II; Nitrites; Oxidation-Reduction; Protein Kinases; Rats; Superoxides; Urea | 2011 |
Effect of butylated hydroxytoluene (E321) pretreatment versus L-arginine on liver injury after sub-lethal dose of endotoxin administration.
Topics: Animals; Arginine; Butylated Hydroxytoluene; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Endotoxins; Food Additives; Glutathione; Glutathione Peroxidase; Liver; Male; Nitrates; Nitrites; Rats; Rats, Wistar; Superoxide Dismutase | 2011 |
Partial deletion of argininosuccinate synthase protects from pyrazole plus lipopolysaccharide-induced liver injury by decreasing nitrosative stress.
Topics: Alanine Transaminase; Animals; Apoptosis; Arginine; Argininosuccinate Synthase; Aspartate Aminotransferases; Caspase 3; Chemical and Drug Induced Liver Injury; Dual Specificity Phosphatase 1; Gene Expression; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Liver; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; Nitrates; Nitric Oxide Synthase Type II; Nitrites; Nitrosation; Phosphorylation; Proteins; Pyrazoles; Receptors, Tumor Necrosis Factor, Type I; Tumor Necrosis Factor-alpha | 2012 |
Requirement of argininosuccinate lyase for systemic nitric oxide production.
Topics: Animals; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Argininosuccinic Aciduria; Cell Line; Disease Models, Animal; Endothelial Cells; Female; Fibroblasts; Gene Knockdown Techniques; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase; Nitrites; RNA, Small Interfering; Sequence Analysis, DNA; Swine | 2011 |
Continuous exposure to L-arginine induces oxidative stress and physiological tolerance in cultured human endothelial cells.
Topics: Arginase; Arginine; Ascorbic Acid; Cells, Cultured; Citrulline; Culture Media; Down-Regulation; Drug Tolerance; Free Radical Scavengers; Gene Expression; Glucose; Human Umbilical Vein Endothelial Cells; Humans; Nitrates; Nitric Oxide Synthase Type III; Nitrites; Oxidative Stress; Polyethylene Glycols; Superoxide Dismutase; Superoxides | 2012 |
Appropriate dose of parenteral arginine enhances immunity of peripheral blood cells and splenocytes in rats with subacute peritonitis.
Topics: Animals; Arginine; Chronic Disease; Concanavalin A; Cytokines; Deficiency Diseases; Dietary Supplements; Dose-Response Relationship, Drug; Immunity; Inflammation; Inflammation Mediators; Leukocytes; Lipopolysaccharides; Macrophages; Male; Nitrates; Nitrites; Parenteral Nutrition; Peritonitis; Rats; Rats, Wistar; Spleen | 2012 |
Mechanism of cellular oxidation stress induced by asymmetric dimethylarginine.
Topics: Arginine; Biopterins; Enzyme Inhibitors; Human Umbilical Vein Endothelial Cells; Humans; Lysine; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase Type III; Nitrites; Oxidative Stress | 2012 |
The dose-dependent immunoregulatory effects of the nitric oxide synthase inhibitor N(G)-nitro-L-arginine methyl ester in rats with sub-acute peritonitis.
Topics: Acute Disease; Animals; Arginine; Body Weight; Cell Proliferation; Cytokines; Dose-Response Relationship, Drug; Humans; Immunomodulation; Infusions, Parenteral; Leukocyte Count; Leukocytes; Male; Nitrates; Nitric Oxide Synthase; Nitrites; Organ Size; Parenteral Nutrition; Peritonitis; Rats; Rats, Wistar; Spleen; Tyrosine | 2012 |
Chronic l-arginine treatment improves metabolic, cardiovascular and liver complications in diet-induced obesity in rats.
Topics: Animals; Arginine; Dietary Carbohydrates; Energy Metabolism; Humans; Inflammation; Liver; Male; Mitochondria; Nitrates; Nitrites; Obesity; Oxidative Stress; Rats; Rats, Wistar | 2013 |
INF-β1b therapy modulates L-arginine and nitric oxide metabolism in patients with relapse remittent multiple sclerosis.
Topics: Adult; Arginase; Arginine; Biomarkers; Drug Monitoring; Female; Follow-Up Studies; Humans; Inflammation; Interferon beta-1b; Interferon-beta; Male; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Nitrates; Nitric Oxide; Nitrites; Nitroso Compounds; Severity of Illness Index; Sulfhydryl Compounds; Tyrosine; Young Adult | 2012 |
Compensatory feto-placental upregulation of the nitric oxide system during fetal growth restriction.
Topics: Adaptation, Physiological; Adult; Arginine; Endothelial Cells; Endothelium, Vascular; Female; Fetal Blood; Fetal Growth Retardation; Fetus; Gene Expression Profiling; Hemoglobins; Humans; Infant, Low Birth Weight; Infant, Newborn; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; Placenta; Pregnancy; Reverse Transcriptase Polymerase Chain Reaction; Ultrasonography; Umbilical Arteries; Umbilical Veins; Up-Regulation | 2012 |
Construction and characterization of nitrate and nitrite respiring Pseudomonas putida KT2440 strains for anoxic biotechnical applications.
Topics: Anaerobiosis; Arginine; Biotechnology; Gene Expression Profiling; Genes, Fungal; Genetic Engineering; Models, Genetic; Nitrates; Nitrites; Pseudomonas putida; Transcriptome | 2013 |
The importance of L-arginine metabolism modulation in diabetic patients with distal symmetric polyneuropathy.
Topics: Aged; Arginase; Arginine; Blood Glucose; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Electrodiagnosis; Female; Fructosamine; Glycated Hemoglobin; Humans; Male; Methylation; Middle Aged; Nitrates; Nitrites; S-Nitrosothiols; Tyrosine | 2013 |
L-arginine as an adjuvant drug in the treatment of sickle cell anaemia.
Topics: Adjuvants, Pharmaceutic; Anemia, Sickle Cell; Arginine; Erythrocyte Indices; Humans; Nitrites; Oxidative Stress | 2013 |
Tetrahydrobiopterin, L-arginine and vitamin C act synergistically to decrease oxidant stress and increase nitric oxide that increases blood flow recovery after hindlimb ischemia in the rat.
Topics: Administration, Oral; Animals; Arginine; Ascorbic Acid; Biopterins; Calcium; Drug Synergism; Hindlimb; Ischemia; Male; Models, Biological; Muscles; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; Oxidative Stress; Phosphorylation; Rats; Rats, Sprague-Dawley; Recovery of Function; Regional Blood Flow | 2012 |
Circulating microparticles carry a functional endothelial nitric oxide synthase that is decreased in patients with endothelial dysfunction.
Topics: Adult; Arginine; Biomarkers; Blotting, Western; Case-Control Studies; Cell-Derived Microparticles; Cells, Cultured; Citrulline; Coronary Stenosis; Down-Regulation; Endothelial Cells; Endothelium, Vascular; Female; Human Umbilical Vein Endothelial Cells; Humans; Immunoprecipitation; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; Reactive Oxygen Species; Time Factors; Vasodilation; Young Adult | 2012 |
Erythrocyte nitric oxide synthase as a surrogate marker for mercury-induced vascular damage: the modulatory effects of naringin.
Topics: Antioxidants; Arginine; Biomarkers; Environmental Pollutants; Erythrocytes; Flavanones; Glucosephosphate Dehydrogenase; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Hemolysis; Humans; Lipid Peroxidation; Mercuric Chloride; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Oxidation-Reduction; Protein Carbonylation; Thiobarbituric Acid Reactive Substances | 2014 |
Diagnostic significance of nitrates and nitrites and L-arginine, in development of hepatorenal syndrome in patients with end stage alcoholic liver cirrhosis.
Topics: Adult; Arginine; Biomarkers; Case-Control Studies; Hepatorenal Syndrome; Humans; Liver Cirrhosis, Alcoholic; Male; Middle Aged; Nitrates; Nitrites | 2013 |
Unilateral nephrectomy causes an early abrupt decrease in plasma arginine and simultaneous reduction in glomerular filtration rate in living kidney donors.
Topics: Arginine; Citrulline; Creatinine; Female; Glomerular Filtration Rate; Humans; Kidney; Kidney Transplantation; Living Donors; Male; Middle Aged; Nephrectomy; Nitric Oxide; Nitrites; Ornithine; Phenylalanine; Thiobarbituric Acid Reactive Substances; Urea | 2013 |
Circulating blood endothelial nitric oxide synthase contributes to the regulation of systemic blood pressure and nitrite homeostasis.
Topics: Animals; Arginine; Blood Pressure; Carbon Radioisotopes; Citrulline; Endothelium, Vascular; Enzyme Inhibitors; Erythrocytes; Homeostasis; Hypertension; Mice; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; Signal Transduction | 2013 |
Evaluation of arginine metabolism for the analysis of M1/M2 macrophage activation in human clinical specimens.
Topics: Adult; Aged; Arginine; Biomarkers; Biopsy; Case-Control Studies; Cell Differentiation; Diagnostic Tests, Routine; Duodenum; Female; Humans; In Vitro Techniques; Macrophage Activation; Macrophages; Male; Middle Aged; Nitrites; Predictive Value of Tests; Whipple Disease | 2013 |
Cyclosporine attenuates arginine transport, in human endothelial cells, through modulation of cationic amino acid transporter-1.
Topics: Arginine; Biological Transport; Cationic Amino Acid Transporter 1; Cyclosporine; Endothelial Cells; Human Umbilical Vein Endothelial Cells; Humans; Immunosuppressive Agents; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; Protein Kinase C-alpha | 2013 |
Increased erythrocytes by-products of arginine catabolism are associated with hyperglycemia and could be involved in the pathogenesis of type 2 diabetes mellitus.
Topics: Adult; Aged; Arginine; Blood Glucose; Carbon Isotopes; Case-Control Studies; Citrulline; Diabetes Mellitus, Type 2; Endothelial Cells; Erythrocytes; Female; Glycosylation; Hemoglobins; Hemolysis; Humans; Hyperglycemia; Male; Malondialdehyde; Metabolic Networks and Pathways; Middle Aged; Models, Biological; Nitric Oxide; Nitrites; Ornithine; Oxidative Stress; Urea | 2013 |
Arginase regulates red blood cell nitric oxide synthase and export of cardioprotective nitric oxide bioactivity.
Topics: Animals; Arginase; Arginine; Biological Transport, Active; Cardiotonic Agents; Enzyme Inhibitors; Erythrocytes; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Reperfusion Injury; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; Rats; Rats, Wistar | 2013 |
Gender differences in oxidative and nitrosative stress parameters in kidney transplant patients on tacrolimus-based immunosuppression.
Topics: Adult; Advanced Oxidation Protein Products; Arginine; Catalase; Female; Healthy Volunteers; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged; Mycophenolic Acid; Nitrates; Nitrites; Oxidative Stress; Prednisone; Sex Factors; Sulfhydryl Compounds; Tacrolimus; Thiobarbituric Acid Reactive Substances | 2014 |
Modulation of nitrergic signalling pathway by American ginseng attenuates chronic unpredictable stress-induced cognitive impairment, neuroinflammation, and biochemical alterations.
Topics: Acetylcholinesterase; Animals; Arginine; Behavior, Animal; Catalase; Cognition Disorders; Corticosterone; Encephalitis; Glutathione; Hippocampus; Male; Mice; NADH Dehydrogenase; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrites; Panax; Plant Extracts; Signal Transduction; Stress, Physiological; Stress, Psychological; Succinate Dehydrogenase; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2014 |
Cross-talk Between Nitrate-Nitrite-NO and NO Synthase Pathways in Control of Vascular NO Homeostasis.
Topics: Animals; Aorta; Arginine; Blood Pressure; Cardiovascular System; Citrulline; Dietary Supplements; Homeostasis; Male; Metabolic Networks and Pathways; Mice, Inbred C57BL; Mice, Knockout; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; Phosphorylation; Rats, Sprague-Dawley | 2015 |
Elevated levels of branched-chain amino acids have little effect on pancreatic islet cells, but L-arginine impairs function through activation of the endoplasmic reticulum stress response.
Topics: Amino Acids, Branched-Chain; Animals; Apoptosis; Arginine; Blotting, Western; Cell Proliferation; Cell Separation; Endoplasmic Reticulum Stress; Glucose; Insulin; Insulin Secretion; Insulin-Secreting Cells; Islets of Langerhans; Male; Nitric Oxide; Nitrites; Rats; Rats, Wistar | 2014 |
Platelet content of nitric oxide synthase 3 phosphorylated at Serine 1177 is associated with the functional response of platelets to aspirin.
Topics: Aged; Arginine; Aspirin; Blood Platelets; Blotting, Western; Collagen; Erythrocytes; Female; Flow Cytometry; Humans; Leukocytes; Light; Male; Mutation; Nitrates; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Phosphorylation; Phosphoserine | 2013 |
Protein kinase C delta modulates endothelial nitric oxide synthase after cardiac arrest.
Topics: Animals; Arginine; Blood Flow Velocity; Cerebral Cortex; Cerebrovascular Circulation; Enzyme Inhibitors; Heart Arrest; Laser-Doppler Flowmetry; Male; Microscopy, Confocal; Nitric Oxide Donors; Nitric Oxide Synthase Type III; Nitrites; Oligopeptides; Protein Kinase C-delta; Rats; Rats, Sprague-Dawley; Substrate Specificity | 2014 |
Arginase-1 deficiency regulates arginine concentrations and NOS2-mediated NO production during endotoxemia.
Topics: Animals; Arginase; Arginine; Cell Count; Citrulline; Cytokines; Endotoxemia; Integrases; Jejunum; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microcirculation; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Organ Specificity; Ornithine; Perfusion; Peroxidase; Receptor, TIE-2; RNA, Messenger | 2014 |
Possible nitric oxide modulation in the protective effects of rutin against experimental head trauma-induced cognitive deficits: behavioral, biochemical, and molecular correlates.
Topics: Acetylcholinesterase; Animals; Arginine; Brain; Caspase 3; Catalase; Cell Death; Cognition Disorders; Craniocerebral Trauma; Drug Evaluation, Preclinical; Glutathione; Lipid Peroxidation; Male; Maze Learning; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Random Allocation; Rats; Rats, Wistar; Rutin; Tumor Necrosis Factor-alpha | 2014 |
L-arginine catabolism is driven mainly towards nitric oxide synthesis in the erythrocytes of patients with type 2 diabetes at first clinical onset.
Topics: Arginase; Arginine; Case-Control Studies; Diabetes Mellitus, Type 2; Electrophoresis, Capillary; Erythrocytes; Female; Glycated Hemoglobin; Humans; Hypertension; Male; Middle Aged; Nitrates; Nitric Oxide; Nitrites | 2015 |
L-arginine/NO pathway is altered in children with haemolytic-uraemic syndrome (HUS).
Topics: Arginine; Case-Control Studies; Child; Child, Preschool; Female; Hemoglobins; Hemolytic-Uremic Syndrome; Hospitalization; Humans; Male; Nitrates; Nitric Oxide; Nitrites; Peritoneal Dialysis; Signal Transduction | 2014 |
Mitigation of lead-induced neurotoxicity by the naringin: erythrocytes as neurons substitute markers.
Topics: Acetylcholinesterase; Arginine; Cells, Cultured; Erythrocytes; Flavanones; Humans; Male; Malondialdehyde; Middle Aged; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Organometallic Compounds; Oxidative Stress; Protein Carbonylation | 2014 |
L-arginine and tetrahydrobiopterin, but not sodium nitrite partially restored erectile dysfunction in aged rats.
Topics: Aging; Animals; Arginine; Biopterins; Dose-Response Relationship, Drug; Erectile Dysfunction; Male; Nitrates; Nitric Oxide Synthase Type III; Nitrites; Penile Erection; Penis; Rats, Wistar; Sodium Nitrite | 2014 |
[The impact of modulators of nitric oxide synthesis on biochemical indices of liver in rats].
Topics: Alanine Transaminase; Animals; Arginine; Aspartate Aminotransferases; Dipeptides; Electron Transport; Electron Transport Complex IV; Injections, Intraperitoneal; Lipid Peroxidation; Liver; Male; Mitochondria, Liver; Mixed Function Oxygenases; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrites; Rats; Rats, Wistar; Succinate Dehydrogenase | 2014 |
Arginase inhibition restores endothelial function in diet-induced obesity.
Topics: Animals; Arginase; Arginine; Diet, High-Fat; Endothelium, Vascular; Enzyme Inhibitors; Gene Expression; Gene Knockdown Techniques; Human Umbilical Vein Endothelial Cells; Humans; Intercellular Adhesion Molecule-1; Male; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type III; Nitrites; Obesity; RNA, Small Interfering | 2014 |
Dietary nitrate increases arginine availability and protects mitochondrial complex I and energetics in the hypoxic rat heart.
Topics: Animals; Arginase; Arginine; Diet; Electron Transport Complex I; Gene Expression Regulation; Heart; Hypoxia-Inducible Factor 1; Male; Myocardium; Nitrates; Nitrites; Oxidative Stress; Oxygen; Rats; Rats, Wistar | 2014 |
Resveratrol affects histone 3 lysine 27 methylation of vessels and blood biomarkers in DOCA salt-induced hypertension.
Topics: Animals; Antioxidants; Arginine; Biomarkers; Blood Pressure; Blood Vessels; Desoxycorticosterone Acetate; Endothelium, Vascular; Fluorescent Antibody Technique; Histones; Hydrogen Sulfide; Hypertension; Lysine; Male; Methylation; Nitrites; Rats, Wistar; Renal Artery; Resveratrol; Stilbenes; Systole; Vasodilation | 2015 |
The Nitric oxide/CGMP/KATP pathway mediates systemic and central antinociception induced by resistance exercise in rats.
Topics: Animals; Arginine; Cyclic GMP; Enzyme Inhibitors; Glyburide; Guanidines; Guanylate Cyclase; KATP Channels; Male; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Nociception; Ornithine; Oxadiazoles; Pain Measurement; Physical Conditioning, Animal; Quinoxalines; Rats; Signal Transduction | 2015 |
Diabetic nephropathy is resistant to oral L-arginine or L-citrulline supplementation.
Topics: Amino Acids; Animals; Arginase; Arginine; Blood Pressure; Citrulline; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dietary Supplements; Fibronectins; Kidney; Male; Membrane Proteins; Mice; Mice, Inbred DBA; Nitrates; Nitric Oxide Synthase Type III; Nitrites; Tumor Necrosis Factor-alpha | 2014 |
Effects of hyperbaric oxygen on nitric oxide generation in humans.
Topics: Adult; Arginine; Breath Tests; Citrulline; Cyclic GMP; Humans; Hyperbaric Oxygenation; Nitrates; Nitric Oxide; Nitrites; Oxygen; Saliva; Tongue; Young Adult | 2015 |
Influence of L-arginine during bovine in vitro fertilization.
Topics: Animals; Arginine; Blastocyst; Cattle; Dose-Response Relationship, Drug; Embryo, Mammalian; Embryonic Development; Female; Fertilization; Fertilization in Vitro; Male; Microscopy, Fluorescence; Nitrates; Nitrites; Spermatozoa | 2014 |
Serum fetuin-A and arginase-1 in human obesity model: Is there any interaction between inflammatory status and arginine metabolism?
Topics: Adiponectin; Adult; alpha-2-HS-Glycoprotein; Arginase; Arginine; Biomarkers; C-Reactive Protein; Enzyme-Linked Immunosorbent Assay; Female; Humans; Leptin; Linear Models; Liver Function Tests; Lysine; Male; Middle Aged; Nitrates; Nitrites; Obesity | 2015 |
Enhancement of Inducible Nitric Oxide Synthase Activity by Low Molecular Weight Peptides Derived from Protamine: A Potential Therapy for Chronic Rhinosinusitis.
Topics: Animals; Arginase; Arginine; Cell Line; Cysteine; Epithelial Cells; Macrophages; Mice; Molecular Weight; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; Peptides; Protamines; Rhinitis, Allergic | 2015 |
Endothelial dysfunction in subjects with chronic cadmium exposure.
Topics: Arginine; Biomarkers; Cadmium Compounds; Endothelium, Vascular; Environmental Exposure; Female; Glutathione; Humans; Linear Models; Malondialdehyde; Nitrites; Thrombomodulin; Vascular Diseases | 2015 |
Arsenic induces structural and compositional colonic microbiome change and promotes host nitrogen and amino acid metabolism.
Topics: Amino Acids; Animals; Arginine; Arsenic; Bacteria; Biofilms; Colon; Genotype; Liver; Male; Mice; Mice, Inbred C57BL; Microbiota; Nitrates; Nitrite Reductases; Nitrites; Nitrogen | 2015 |
Possible involvement of nitrergic and opioidergic systems in the modulatory effect of acute chloroquine treatment on pentylenetetrazol induced convulsions in mice.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; Anticonvulsants; Arginine; Chloroquine; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanidines; Hippocampus; Indazoles; Male; Mice; Naltrexone; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Pentylenetetrazole; Seizures; Signal Transduction; Time Factors | 2016 |
Plasma kallikrein-bradykinin pathway promotes circulatory nitric oxide metabolite availability during hypoxia.
Topics: Acclimatization; Adult; Altitude; Angiotensinogen; Arginine; Bradykinin; Citrulline; Humans; Hypoxia; Isoprostanes; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; Oxidation-Reduction; Oxidative Stress; Plasma Kallikrein; Protein Carbonylation; Proteome; Signal Transduction | 2016 |
The Nitric Oxide Synthase Inhibitor NG-Nitro-L-Arginine Methyl Ester Diminishes the Immunomodulatory Effects of Parental Arginine in Rats with Subacute Peritonitis.
Topics: Adjuvants, Immunologic; Animals; Arginine; Body Weight; Cytokines; Immunophenotyping; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrites; Peritonitis; Rats; Rats, Wistar | 2016 |
Gonadotropin-releasing hormone agonist prevents l-arginine induced immune dysfunction independent of gonadal steroids: Relates with a decline in elevated thymus and brain nitric oxide levels.
Topics: Animals; Arginine; Brain; DNA Fragmentation; Female; Gonadal Steroid Hormones; Gonadotropin-Releasing Hormone; Immunity, Cellular; Immunity, Humoral; Immunosuppression Therapy; Leuprolide; Male; Mice; Nitric Oxide; Nitrites; Thymus Gland | 2016 |
The Association of Dietary l-Arginine Intake and Serum Nitric Oxide Metabolites in Adults: A Population-Based Study.
Topics: Adult; Age Factors; Arginine; Biomarkers; Body Mass Index; Chi-Square Distribution; Cross-Sectional Studies; Diet; Female; Humans; Hypertension; Iran; Linear Models; Male; Middle Aged; Multivariate Analysis; Nitrates; Nitric Oxide; Nitrites; Sex Factors; Surveys and Questionnaires | 2016 |
Peritoneal dialysis impairs nitric oxide homeostasis and may predispose infants with low systolic blood pressure to cerebral ischemia.
Topics: Arginine; Blood Pressure; Brain; Brain Ischemia; Cerebrovascular Circulation; Cyclic GMP; Female; Homeostasis; Humans; Hypotension; Infant; Infant, Newborn; Male; Nitrates; Nitric Oxide; Nitrites; Peritoneal Dialysis | 2016 |
Effects of Dietary l-Arginine on Nitric Oxide Bioavailability in Obese Normotensive and Obese Hypertensive Subjects.
Topics: Arginase; Arginine; Biological Availability; Blood Pressure; Calcium Channels; Clinical Trials as Topic; Diet; Endothelial Cells; Humans; Hypertension; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; Obesity; Risk Factors; TRPV Cation Channels | 2016 |
Hypoxia causes increased monocyte nitric oxide synthesis which is mediated by changes in dimethylarginine dimethylaminohydrolase 2 expression in animal and human models of normobaric hypoxia.
Topics: Adolescent; Adult; Amidohydrolases; Animals; Arginine; Cell Hypoxia; Humans; Hypoxia; Macrophages, Peritoneal; Male; Mice, Knockout; Middle Aged; Monocytes; Nitrates; Nitric Oxide; Nitrites; Young Adult | 2016 |
Two weeks of watermelon juice supplementation improves nitric oxide bioavailability but not endurance exercise performance in humans.
Topics: Arginine; Arterial Pressure; Blood Glucose; Citrulline; Citrullus; Dietary Supplements; Fruit and Vegetable Juices; Heart Rate; Humans; Lactic Acid; Male; Malus; Nitric Oxide; Nitrites; Oxygen Consumption; Physical Endurance; Pulmonary Gas Exchange; Young Adult | 2016 |
Dietary Nitrate Acutely and Markedly Increased Exhaled Nitric Oxide in a Cystic Fibrosis Case.
Topics: Arginine; Child; Cystic Fibrosis; Diet; Exhalation; Humans; Inflammation; Iron; Male; Nitrates; Nitric Oxide; Nitrites; Placebos; Respiratory Function Tests; Treatment Outcome | 2016 |
Nilotinib, a tyrosine kinase inhibitor exhibits protection against acute pancreatitis-induced lung and liver damage in rats.
Topics: Acute Disease; Amylases; Animals; Anti-Inflammatory Agents; Antioxidants; Arginine; Biomarkers; Cytoprotection; Disease Models, Animal; Lipase; Liver Diseases; Lung Injury; Male; NF-kappa B; Nitrates; Nitrites; Pancreatitis; Protein Kinase Inhibitors; Pyrimidines; Rats, Sprague-Dawley; Time Factors; Transforming Growth Factor beta1 | 2017 |
Effects of fetal exposure to high-fat diet or maternal hyperglycemia on L-arginine and nitric oxide metabolism in lung.
Topics: Animals; Arginine; Diet, High-Fat; Female; Hyperglycemia; Lung; Mice; Nitrates; Nitric Oxide; Nitrites; Pregnancy; Prenatal Exposure Delayed Effects | 2017 |
Involvement of hypothalamic nitric oxide signaling in the modulation of a rat's exercise capacity.
Topics: Animals; Arginine; Catheters, Indwelling; Cell Count; Central Nervous System Agents; Enzyme Inhibitors; Fatigue; Hypothalamus; Immunohistochemistry; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type I; Nitrites; Random Allocation; Rats, Sprague-Dawley; Running | 2017 |
Cellular interactions between L-arginine and asymmetric dimethylarginine: Transport and metabolism.
Topics: Arginine; Biological Transport; Cell Line; Humans; Nitrites | 2017 |
Nitric Oxide Mediates Nitrite-Sensing and Acclimation and Triggers a Remodeling of Lipids.
Topics: Acclimatization; Adaptation, Physiological; Aldehydes; Arginine; Caspases; Cell Death; Diatoms; Ferredoxins; Galactolipids; Galactosyltransferases; Gene Expression Profiling; Gene Expression Regulation, Plant; Lipid Metabolism; Nitric Oxide; Nitrite Reductases; Nitrites; Plastids; S-Nitroso-N-Acetylpenicillamine; Transcription, Genetic; Triglycerides | 2017 |
Blood asymmetric dimethylarginine and nitrite/nitrate concentrations in short-stature children born small for gestational age with and without growth hormone therapy.
Topics: Arginine; Biomarkers; Body Height; Case-Control Studies; Child; Child, Preschool; Dwarfism; Female; Growth Hormone; Humans; Infant, Newborn; Infant, Small for Gestational Age; Longitudinal Studies; Male; Nitrates; Nitrites | 2018 |
Impaired Arginine Metabolism Coupled to a Defective Redox Conduit Contributes to Low Plasma Nitric Oxide in Polycystic Ovary Syndrome.
Topics: Amidohydrolases; Arginine; Argininosuccinate Lyase; Cationic Amino Acid Transporter 1; Female; Humans; Hydrogen Peroxide; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Oxidation-Reduction; Polycystic Ovary Syndrome; Protein-Arginine N-Methyltransferases; Repressor Proteins | 2017 |
Relationship between asymmetric dimethylarginine, nitrite and genetic polymorphisms: Impact on erectile dysfunction therapy.
Topics: Amidohydrolases; Arginine; Biomarkers; Erectile Dysfunction; Humans; Male; Nitrites; Phosphodiesterase 5 Inhibitors; Polymorphism, Genetic; Sildenafil Citrate | 2017 |
Functional status of microvascular vasomotion is impaired in spontaneously hypertensive rat.
Topics: Animals; Arginine; Blood Glucose; Blood Pressure; Cell Movement; Dimerization; Endothelial Cells; Glucose; Hypertension; Insulin; Islets of Langerhans; Malondialdehyde; Mercaptoethanol; Microcirculation; Nitric Oxide Synthase Type III; Nitrites; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 2017 |
Inverse correlation between maternal plasma asymmetric dimethylarginine (ADMA) and birthweight percentile in women with impaired placental perfusion: circulating ADMA as an NO-independent indicator of fetal growth restriction?
Topics: Adult; Arginine; Biomarkers; Birth Weight; Female; Fetal Growth Retardation; Fetus; Gestational Age; Humans; Infant, Newborn; Male; Nitrates; Nitric Oxide; Nitrites; Placenta; Pre-Eclampsia; Pregnancy; Pregnancy Outcome | 2018 |
Experience of correcting endothelial dysfunction in children-residents of radioactively contaminated areas by nitric oxide potential donator citrulline.
Topics: Arginine; Bronchial Spasm; Cardiovascular Diseases; Chernobyl Nuclear Accident; Child; Citrulline; Endothelium, Vascular; Female; Humans; Immunity, Cellular; Immunity, Humoral; Lipid Peroxidation; Malates; Male; Nitric Oxide; Nitric Oxide Donors; Nitrites; Radiation Dosage; Radiation Exposure; Radioactive Pollutants; Rural Population; Survivors; T-Lymphocytes; Ukraine; Urban Population | 2017 |
5,10,15,20-Tetrakis(4-sulfonatophenyl)porphyrinato iron(III) chloride (FeTPPS), a peroxynitrite decomposition catalyst, catalyzes protein tyrosine nitration in the presence of hydrogen peroxide and nitrite.
Topics: Animals; Arginine; Catalysis; Cattle; Chromatography, Liquid; Food Preservation; Hep G2 Cells; Humans; Hydrogen Peroxide; Nitrates; Nitrites; Serum Albumin, Bovine; Sodium Nitrite; Tandem Mass Spectrometry; Tyrosine | 2018 |
Anticonvulsant effect of minocycline on pentylenetetrazole-induced seizure in mice: involvement of nitric oxide and N-methyl-d-aspartate receptor.
Topics: Animals; Anticonvulsants; Arginine; Enzyme Inhibitors; Hippocampus; Male; Mice; Minocycline; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Pentylenetetrazole; Receptors, N-Methyl-D-Aspartate; Seizures; Time Factors | 2018 |
Oxidative stress, NOx/l-arginine ratio and glutathione/glutathione S-transferase ratio as predictors of 'sterile inflammation' in patients with alcoholic cirrhosis and hepatorenal syndrome type II.
Topics: Adult; Aged; Arginine; Biomarkers; Female; Glutathione; Glutathione Transferase; Hepatorenal Syndrome; Humans; Inflammation; Liver; Liver Cirrhosis, Alcoholic; Male; Middle Aged; Nitrates; Nitrites; Oxidative Stress; Retrospective Studies | 2018 |
The role of nitric oxide-cGMP pathway in selegiline antidepressant-like effect in the mice forced swim test.
Topics: Animals; Antidepressive Agents; Arginine; Cyclic GMP; Drug Synergism; Fluoxetine; Guanidines; Hippocampus; Immobility Response, Tonic; Indazoles; Male; Methylene Blue; Mice; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Prefrontal Cortex; Selegiline; Signal Transduction; Sildenafil Citrate; Swimming | 2018 |
Investigation of N
Topics: Arginine; Gas Chromatography-Mass Spectrometry; Humans; Nitrates; Nitrites | 2018 |
Nitric oxide in the dorsal periaqueductal gray mediates the panic-like escape response evoked by exposure to hypoxia.
Topics: 2-Amino-5-phosphonovalerate; Amygdala; Animals; Arginine; Escape Reaction; Hypothalamus; Hypoxia; Male; Maze Learning; Microinjections; Motor Activity; Nitric Oxide; Nitrites; Panic; Periaqueductal Gray; Rats | 2019 |
Exogenous l-ARGININE does not stimulate production OF NO or cGMP within the rat corporal smooth muscle cells in culture.
Topics: Animals; Arginine; Cells, Cultured; Citrulline; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Male; Muscle, Smooth; Myocytes, Smooth Muscle; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Penis; Phosphodiesterase 5 Inhibitors; Rats, Sprague-Dawley | 2019 |
Nitric oxide production is downregulated during respiratory syncytial virus persistence by constitutive expression of arginase 1.
Topics: Arginase; Arginine; Down-Regulation; Humans; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; Respiratory Syncytial Virus Infections; Respiratory Syncytial Virus, Human; Virus Replication | 2019 |
Systemic translation of locally infiltrated epidermal growth factor in diabetic lower extremity wounds.
Topics: Aged; Arginine; Biomarkers; Blood Sedimentation; C-Reactive Protein; Chemokine CCL3; Cytokines; Diabetic Foot; Epidermal Growth Factor; fas Receptor; Female; Humans; Injections, Intralesional; Lysine; Male; Middle Aged; Nitrates; Nitrites; Receptor for Advanced Glycation End Products; Recombinant Proteins; Wound Healing | 2019 |
BaiJiu Increases Nitric Oxide Bioactivity of Chinese Herbs Used to Treat Coronary Artery Disease Through the NO3--NO2--NO Pathway.
Topics: Animals; Aorta; Arginine; Cell Hypoxia; Cells, Cultured; Coronary Artery Disease; Coronary Vessels; Drugs, Chinese Herbal; Endothelial Cells; Female; Humans; Male; Mice, Inbred C57BL; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; Signal Transduction; Vasodilation; Vasodilator Agents | 2019 |
The changes in dynamics of ornithine cycle components levels during the acute period of Polytrauma.
Topics: Arginase; Arginine; Humans; Multiple Trauma; Nitrates; Nitric Oxide; Nitrites; Ornithine; Peroxynitrous Acid | 2019 |
The effects of oral arginine on its metabolic pathways in Sprague-Dawley rats.
Topics: Administration, Oral; Animals; Arginase; Arginine; Cationic Amino Acid Transporter 1; Creatine; Dietary Supplements; Male; Metabolic Networks and Pathways; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Sprague-Dawley | 2020 |
Regulation of the biosynthesis of endogenous nitric oxide and abscisic acid in stored peaches by exogenous nitric oxide and abscisic acid.
Topics: Abscisic Acid; Adenosylmethionine Decarboxylase; Aldehyde Oxidase; Arginine; Carboxy-Lyases; Dioxygenases; Food Storage; Fruit; Gene Expression Regulation, Plant; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Oxidoreductases; Plant Proteins; Prunus persica; Spermidine; Spermine | 2020 |
Protein synthesis inhibition promotes nitric oxide generation and activation of CGKII-dependent downstream signaling pathways in the retina.
Topics: Animals; Arginine; Cell Survival; Cells, Cultured; Chick Embryo; Chickens; Cyclic GMP-Dependent Protein Kinase Type II; Elongation Factor 2 Kinase; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type I; Nitrites; Phosphorylation; Protein Synthesis Inhibitors; Retina; Signal Transduction | 2020 |
Urinary albumin-to-creatinine ratio is inversely related to nitric oxide synthesis in young black adults: the African-PREDICT study.
Topics: Adult; Albumins; Arginine; Biomarkers; Creatinine; Homoarginine; Humans; Hypertension; Nitrates; Nitric Oxide; Nitrites | 2021 |
Nitric oxide mediates the antidepressant-like effect of modafinil in mouse forced swimming and tail suspension tests.
Topics: Animals; Antidepressive Agents; Arginine; Depression; Hindlimb Suspension; Hippocampus; Mice; Modafinil; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Swimming | 2020 |
Impact of the dynamics of the catalytic arginine on nitrite and chlorite binding by dimeric chlorite dismutase.
Topics: Arginine; Bacterial Proteins; Catalysis; Chlorides; Cyanothece; Nitrites; Oxidoreductases; Protein Multimerization | 2022 |
Effects of nitric oxide modulators and antioxidants on endocrine and cellular markers of acute stress in rats.
Topics: Acute Disease; Animals; Antioxidants; Arginine; Biomarkers; Corticosterone; Endocrine System; Female; Glutathione; HSP70 Heat-Shock Proteins; Male; Malondialdehyde; NF-kappa B; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats, Wistar; Restraint, Physical; Stress, Psychological; Superoxide Dismutase | 2022 |
Exercise and nitrite prevent and Nω-nitrol-L-arginine methyl ester reproduces imbalance in the nuclear factor-κB/NADPH oxidase 2 and nuclear factor erythroid 2-related factor 2/NADPH oxidase 4/endothelial nitric oxide synthase systems in diabetes.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Hydrogen Peroxide; NADPH Oxidase 2; NADPH Oxidase 4; NF-E2-Related Factor 2; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; Nitroglycerin; Oxidative Stress; Rats | 2021 |
Characterization of the L-Arginine/Nitric Oxide Pathway and Oxidative Stress in Pediatric Patients with Atopic Diseases.
Topics: Arginine; Asthma; Child; Dermatitis, Atopic; Female; Homoarginine; Humans; Male; Malondialdehyde; Nitrates; Nitric Oxide; Nitrites; Oxidative Stress; Signal Transduction | 2022 |
Cyclic di-GMP triggers the hypoxic adaptation of Mycobacterium bovis through a metabolic switching regulator ArgR.
Topics: Arginine; Bacterial Proteins; Cyclic GMP; Gene Expression Regulation, Bacterial; Humans; Hypoxia; Mycobacterium bovis; Mycobacterium tuberculosis; Nitrites | 2022 |
Migraine Attacks Triggered by Ingestion of Watermelon.
Topics: Adult; Arginine; Citrullus; Eating; Headache; Humans; Migraine Disorders; Nitric Oxide; Nitrites; Young Adult | 2023 |
l-Arginine/nitric oxide pathway and oxidative stress in adults with ADHD: Effects of methylphenidate treatment.
Topics: Adult; Arginine; Attention Deficit Disorder with Hyperactivity; Child; Creatinine; Humans; Methylphenidate; Nitrates; Nitric Oxide; Nitrites; Oxidative Stress | 2023 |