arginine has been researched along with metformin in 48 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (4.17) | 18.7374 |
| 1990's | 3 (6.25) | 18.2507 |
| 2000's | 16 (33.33) | 29.6817 |
| 2010's | 22 (45.83) | 24.3611 |
| 2020's | 5 (10.42) | 2.80 |
| Authors | Studies |
|---|---|
| Audic, N; Ermolenko, L; Franck, G; Garcia-Alvarez, MC; Martin, MT; Nhiri, N; Potier, P; Sasaki, NA; Wang, Q | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jensen, SL; Kühl, C; Nielsen, OV; Pedersen, J | 1 |
| Carpentier, J; Lefebvre, PJ; Luyckx, AS | 1 |
| Cooper, GJ; Moore, CX | 1 |
| Acampora, R; De Rosa, N; Giugliano, D; Giunta, R; Marfella, R; Verrazzo, G; Ziccardi, P | 1 |
| Carmellini, M; Coppelli, A; Del Guerra, S; Giannarelli, R; Lorenzetti, M; Lupi, R; Marchetti, P; Mosca, F; Navalesi, R; Tellini, C | 1 |
| Boggi, U; Del Guerra, S; Del Prato, S; Fierabracci, V; Lupi, R; Marchetti, P; Marselli, L; Mosca, F; Novelli, M; Patanè, G; Piro, S | 1 |
| Abbasi, F; Asagami, T; Cooke, JP; Lamendola, C; McLaughlin, T; Reaven, GM; Stuelinger, M; Tsao, PS | 1 |
| Brizzi, P; Maioli, M; Secchi, G; Severino, C; Solinas, A; Tonolo, G | 1 |
| Berg, C; Herrmann, BL; Mann, K; Nowak, T; Renzing-Koehler, K; Saller, B; Vogel, E | 1 |
| Aktas, A; Dilek, S; Erdal, EM; Ertunc, D; Tok, EC | 1 |
| Desai, M; Huang, WX; Joshi, Y; Tang, Q; Vivilecchia, RV; Yang, R | 1 |
| Elbein, SC; Kern, PA; Rasouli, N; Reece, EA | 1 |
| Heutling, D; Kaltwasser, P; Kleinstein, J; Krzyzanowska, K; Lehnert, H; Mittermayer, F; Nickel, I; Randeva, H; Schernthaner, G; Schulz, H; Westphal, S; Wolzt, M | 1 |
| Bank, AJ; Gonzalez-Campoy, JM; Kaiser, DR; Kelly, AS; Thelen, AM | 1 |
| Nelson, SM; Sattar, N | 1 |
| Baser, I; Dede, M; Erbil, MK; Kenar, L; Oktenli, C; Ozgurtas, T; Sanisoglu, SY; Tapan, S; Yenen, MC; Yesilova, Z | 1 |
| Asbún, J; Ceballos, G; Elisa, ZN; Emma, MN; Guzman, M; Hicks, J; Meaney, A; Meaney, E; Samaniego, V; Vela, A; Zempoalteca, JC | 1 |
| Barter, PJ; Brown, BE; Davies, MJ; Nobécourt, E; Rye, KA; Yadav, S; Zeng, J | 1 |
| Hutchison, SK; McGrath, BP; Meyer, C; Moran, LJ; Teede, HJ; Zoungas, S | 1 |
| Bunck, MC; Cornér, A; Deng, W; Diamant, M; Eliasson, B; Heine, RJ; Kendall, DM; Malloy, JL; Shaginian, RM; Smith, U; Taskinen, MR; Yki-Järvinen, H | 1 |
| Butler, AE; Butler, PC; Cox, HI; Dry, S; Galasso, R; Gurlo, T; Matveyenko, AV; Moshtaghian, A | 1 |
| Bodmer, CW; Ceriello, A; Chittari, MV; Rabbani, N; Thornalley, PJ; Zehnder, D | 1 |
| Chen, E; Chen, L; Choi, JH; Giacomini, KM; Iwamoto, Y; Iwasaki, N; Kubo, M; Nakamura, S; Sali, A; Schlessinger, A; Segenthelar, J; Takizawa, M | 1 |
| Aydin, M; Batioglu, S; Erdogan, G; Kilic, S; Yilmaz, N; Zulfikaroglu, E | 1 |
| Kanazawa, I; Sugimoto, T; Yamaguchi, T; Yamamoto, M | 1 |
| Anders, S; Forst, T; Michelson, G; Mitry, M; Pfützner, A; Ratter, F; Weber, MM; Wilhelm, B | 1 |
| Auge, D; Endress, B; Fromm, MF; König, J; Maas, R; Mieth, M; Strobel, J | 1 |
| Carbone, A; Ciccarelli, L; Derosa, G; Fogari, E; Franzetti, IG; Maffioli, P; Piccinni, MN; Querci, F | 1 |
| Abdul-Ghani, M; Cakirca, M; Camli, AA; Cikrikcioglu, MA; Erkoc, R; Hursitoglu, M; Kanat, M; Karatoprak, C; Kiskac, M; Soysal, P; Zorlu, M | 1 |
| Hsu, CN; Huang, LT; Kuo, HC; Tain, YL; Tsai, CM | 1 |
| Bal, F; Bekpinar, S; Gurdol, F; Kusku-Kiraz, Z; Önder, S; Unlucerci, Y; Uysal, M | 1 |
| Bratt, JM; Kenyon, NJ; Linderholm, AL; Schuster, GU; Zeki, AA | 1 |
| Chyrchel, B; Golay, A; Kruszelnicka, O; Surdacki, A | 1 |
| Bieri, O; Bonati, U; Deuster, S; Erne, B; Fischer, D; Fischmann, A; Frank, S; Gloor, M; Gueven, N; Hafner, P; Neuhaus, C; Peters, T; Pohlman, U; Rubino, D; Rutz, E; Schmid, M; Sinnreich, M | 1 |
| Berriche, O; Bouzidi, H; Haddad, M; Hammami, M; Kerkeni, M; Knani, I | 1 |
| Bollenbach, A; Bonati, U; Fischer, D; Hafner, P; Hanff, E; Kayacelebi, AA; Tsikas, D | 1 |
| Fortuna, P; Kałuża, B; Prof, AG; Sutkowska, E; Sutkowska, K; Wiśniewski, J | 1 |
| Al-Dhabi, NA; Arasu, MV; Arockiaraj, J; C, M; Chatterjee, S; Choi, KC; Karuppiah, K; Natarajan, S; Raj, V; Ramanujam, GM; Ramasamy, M | 1 |
| Kooy, A; Lehert, P; Schalkwijk, CG; Stehouwer, CDA; Top, WMC | 1 |
| Ahmad, S; Alenazi, F; Alharbi, MS; Ashraf, JM; Hagbani, TA; Khaja, ASS; Qamar, M; Rafi, Z; Saleem, M; Zafar, M | 1 |
| Chen, M; Jia, B; Li, Y; Liu, X; Liu, Y; Ma, T | 1 |
2 review(s) available for arginine and metformin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Novel therapeutic strategies for adult obese asthmatics.
Topics: Adenylate Kinase; Adult; Airway Remodeling; Arginine; Asthma; Dietary Supplements; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation Mediators; Metformin; Molecular Targeted Therapy; Obesity | 2014 |
19 trial(s) available for arginine and metformin
| Article | Year |
|---|---|
Metformin improves hemodynamic and rheological responses to L-arginine in NIDDM patients.
Topics: Analysis of Variance; Arginine; Blood Glucose; Blood Pressure; Blood Viscosity; Diabetes Mellitus, Type 2; Epinephrine; Female; Heart Rate; Hemodynamics; Humans; Hypoglycemic Agents; Insulin; Male; Metformin; Middle Aged; Norepinephrine; Platelet Aggregation; Rheology | 1996 |
Metformin treatment lowers asymmetric dimethylarginine concentrations in patients with type 2 diabetes.
Topics: Arginine; Blood Glucose; Creatinine; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Sulfonylurea Compounds; Treatment Outcome | 2002 |
Effects of a combination of recombinant human growth hormone with metformin on glucose metabolism and body composition in patients with metabolic syndrome.
Topics: Aged; Arginine; Blood Glucose; Blood Pressure; Body Composition; Body Constitution; Body Weight; Diabetes Mellitus, Type 2; Double-Blind Method; Fibrinogen; Glucose Tolerance Test; Glycated Hemoglobin; Growth Hormone-Releasing Hormone; Human Growth Hormone; Humans; Insulin Resistance; Insulin-Like Growth Factor I; Lipids; Male; Metabolic Syndrome; Metformin; Middle Aged; Obesity; Placebos; Testosterone | 2004 |
Effects of pioglitazone and metformin on beta-cell function in nondiabetic subjects at high risk for type 2 diabetes.
Topics: Adult; Aged; Arginine; Body Composition; Diabetes Mellitus, Type 2; Female; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Insulin-Secreting Cells; Male; Metformin; Middle Aged; Pioglitazone; Risk Factors; Thiazolidinediones | 2007 |
Rosiglitazone improves endothelial function and inflammation but not asymmetric dimethylarginine or oxidative stress in patients with type 2 diabetes mellitus.
Topics: Adult; Aged; Arginine; Biomarkers; Blood Glucose; Blood Pressure; Brachial Artery; C-Reactive Protein; Carotid Arteries; Diabetes Mellitus; Double-Blind Method; Drug Therapy, Combination; Elasticity; Endothelium, Vascular; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Inflammation; Insulin; Male; Metformin; Middle Aged; Oxidative Stress; Rosiglitazone; Thiazolidinediones; Treatment Outcome; Vasodilation | 2007 |
Metformin, arterial function, intima-media thickness and nitroxidation in metabolic syndrome: the mefisto study.
Topics: Adult; Arginine; Carotid Arteries; Female; Humans; Hypoglycemic Agents; Male; Metabolic Syndrome; Metformin; Middle Aged; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Tunica Intima | 2008 |
Endothelial function and insulin resistance in polycystic ovary syndrome: the effects of medical therapy.
Topics: Adult; Arginine; Biomarkers; Blood Glucose; C-Reactive Protein; Contraceptives, Oral, Combined; Contraceptives, Oral, Hormonal; Cyproterone Acetate; Drug Therapy, Combination; Endothelium, Vascular; Ethinyl Estradiol; Female; Humans; Hyperandrogenism; Hypoglycemic Agents; Inflammation Mediators; Insulin; Insulin Resistance; Lipids; Metformin; Plasminogen Activator Inhibitor 1; Polycystic Ovary Syndrome; Sex Hormone-Binding Globulin; Testosterone; Time Factors; Treatment Outcome; Vasodilation; von Willebrand Factor | 2010 |
One-year treatment with exenatide improves beta-cell function, compared with insulin glargine, in metformin-treated type 2 diabetic patients: a randomized, controlled trial.
Topics: Arginine; Blood Glucose; Body Mass Index; C-Peptide; Diabetes Mellitus, Type 2; Exenatide; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Insulin Glargine; Insulin Secretion; Insulin-Secreting Cells; Insulin, Long-Acting; Kinetics; Male; Metformin; Middle Aged; Peptides; Venoms | 2009 |
Inflammatory-metabolic parameters in obese and nonobese normoandrogenemic polycystic ovary syndrome during metformin and oral contraceptive treatment.
Topics: Adult; Arginine; Body Mass Index; Cardiovascular Diseases; Contraceptives, Oral; Female; Homocysteine; Humans; Hypoglycemic Agents; Insulin Resistance; Metformin; Obesity; Polycystic Ovary Syndrome; Prospective Studies; Risk Factors; Young Adult | 2011 |
Effects of metformin and pioglitazone on serum pentosidine levels in type 2 diabetes mellitus.
Topics: Aged; Arginine; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Hypoglycemic Agents; Lysine; Male; Metformin; Middle Aged; Pioglitazone; Thiazolidinediones; Time Factors | 2011 |
Addition of liraglutide in patients with Type 2 diabetes well controlled on metformin monotherapy improves several markers of vascular function.
Topics: Adult; Aged; Arginine; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 2; Drug Therapy, Combination; E-Selectin; Endothelium, Vascular; Female; Glucagon-Like Peptide 1; Humans; Hypoglycemic Agents; Liraglutide; Male; Metformin; Microcirculation; Middle Aged; Plasminogen Activator Inhibitor 1; Proinsulin; Prospective Studies | 2012 |
Variation in inflammatory markers and glycemic parameters after 12 months of exenatide plus metformin treatment compared with metformin alone: a randomized placebo-controlled trial.
Topics: Aged; Arginine; Biomarkers; Blood Glucose; Body Mass Index; Body Weight; C-Peptide; Chimerin Proteins; Diabetes Mellitus, Type 2; Diet; Double-Blind Method; Drug Therapy, Combination; Endpoint Determination; Exenatide; Female; Glucose Clamp Technique; Humans; Hypoglycemic Agents; Inflammation; Insulin Resistance; Male; Metformin; Middle Aged; Peptides; Resistin; Risk Factors; Serpins; Venoms | 2013 |
Restoring Insulin Secretion (RISE): design of studies of β-cell preservation in prediabetes and early type 2 diabetes across the life span.
Topics: Adolescent; Adult; Aged; Arginine; Blood Glucose; C-Peptide; Child; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Gastroplasty; Glucagon-Like Peptide 1; Glucose Clamp Technique; Glucose Tolerance Test; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Liraglutide; Male; Metformin; Middle Aged; Prediabetic State; Young Adult | 2014 |
Effect of vildagliptin add-on treatment to metformin on plasma asymmetric dimethylarginine in type 2 diabetes mellitus patients.
Topics: Adamantane; Adult; Aged; Arginine; C-Reactive Protein; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Drug Combinations; Female; Fibrinogen; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Nitric Oxide; Nitriles; Pyrrolidines; Vildagliptin | 2014 |
Differential associations of circulating asymmetric dimethylarginine and cell adhesion molecules with metformin use in patients with type 2 diabetes mellitus and stable coronary artery disease.
Topics: Aged; Aged, 80 and over; Arginine; Cell Adhesion Molecules; Coronary Artery Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Humans; Male; Metformin; Middle Aged; Time Factors | 2015 |
Improved Muscle Function in Duchenne Muscular Dystrophy through L-Arginine and Metformin: An Investigator-Initiated, Open-Label, Single-Center, Proof-Of-Concept-Study.
Topics: Arginine; Biopsy; Child; Drug Therapy, Combination; Humans; Magnetic Resonance Imaging; Metformin; Muscle, Skeletal; Muscular Dystrophy, Duchenne; Nitric Oxide Synthase Type I; Pilot Projects | 2016 |
Effects of single and combined metformin and L-citrulline supplementation on L-arginine-related pathways in Becker muscular dystrophy patients: possible biochemical and clinical implications.
Topics: Adult; Amidinotransferases; Arginine; Citrulline; Creatinine; Dietary Supplements; Female; Glycine; Guanidinoacetate N-Methyltransferase; Homoarginine; Humans; Male; Metformin; Middle Aged; Muscle, Skeletal; Muscular Dystrophy, Duchenne; Nitrates; Nitric Oxide Synthase Type I; Treatment Outcome; Young Adult | 2018 |
Metformin has no impact on nitric oxide production in patients with pre-diabetes.
Topics: Adult; Arginine; Citrulline; Female; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Nitric Oxide; Prediabetic State | 2021 |
Effect of metformin on arginine and dimethylarginines in patients with advanced type 2 diabetes: A post hoc analysis of a randomized trial.
Topics: Arginine; Biomarkers; Diabetes Mellitus, Type 2; Humans; Metformin; Nitric Oxide | 2022 |
27 other study(ies) available for arginine and metformin
| Article | Year |
|---|---|
N-Terminal 2,3-diaminopropionic acid (Dap) peptides as efficient methylglyoxal scavengers to inhibit advanced glycation endproduct (AGE) formation.
Topics: beta-Alanine; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Glycation End Products, Advanced; Magnetic Resonance Spectroscopy; Peptides; Pyruvaldehyde | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
The effect of metformin on the arginine induced insulin- and glucagon release in pigs.
Topics: Animals; Arginine; Blood Glucose; Glucagon; Insulin; Insulin Secretion; Metformin; Secretory Rate; Swine | 1979 |
Influence of metformin on arginine-induced glucagon secretion in human diabetes.
Topics: Adult; Aged; Arginine; Blood Glucose; Body Weight; Diabetes Mellitus; Fatty Acids, Nonesterified; Female; Glucagon; Humans; Insulin; Male; Metformin; Middle Aged | 1975 |
Co-secretion of amylin and insulin from cultured islet beta-cells: modulation by nutrient secretagogues, islet hormones and hypoglycemic agents.
Topics: Amyloid; Animals; Arginine; Cell Line; Cricetinae; Glucagon; Glucose; Glyburide; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Islet Amyloid Polypeptide; Islets of Langerhans; Kinetics; Metformin; Somatostatin; Tolbutamide | 1991 |
The biguanide compound metformin prevents desensitization of human pancreatic islets induced by high glucose.
Topics: Adolescent; Adult; Arginine; Biguanides; Cadaver; Dose-Response Relationship, Drug; Female; Glucose; Glyburide; Humans; Hypoglycemic Agents; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Metformin; Middle Aged | 1999 |
Lipotoxicity in human pancreatic islets and the protective effect of metformin.
Topics: Arginine; Fatty Acids, Nonesterified; Glucose; Glyburide; Humans; Hypoglycemic Agents; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Metformin; Oleic Acid; Palmitates | 2002 |
Low-dose dexamethasone in the rat: a model to study insulin resistance.
Topics: Animals; Arginine; Blood Pressure; Dexamethasone; Dose-Response Relationship, Drug; Drug Combinations; Glucocorticoids; Hypertension; Hypoglycemic Agents; Injections, Subcutaneous; Insulin Resistance; Isosorbide Dinitrate; Male; Metformin; Rats; Rats, Wistar | 2002 |
The importance of IRS-1 Gly972Arg polymorphism in evaluating the response to metformin treatment in polycystic ovary syndrome.
Topics: Adult; Androgens; Arginine; Female; Glycine; Humans; Hypoglycemic Agents; Insulin Receptor Substrate Proteins; Insulin Resistance; Metformin; Phosphoproteins; Polycystic Ovary Syndrome; Polymorphism, Genetic; Steroids | 2005 |
Elimination of metformin-croscarmellose sodium interaction by competition.
Topics: Arginine; Binding, Competitive; Carboxymethylcellulose Sodium; Cyclohexanes; Drug Combinations; Excipients; Hypoglycemic Agents; Metformin; Models, Chemical; Nateglinide; Phenylalanine; Tablets; Technology, Pharmaceutical | 2006 |
Asymmetrical dimethylarginine, inflammatory and metabolic parameters in women with polycystic ovary syndrome before and after metformin treatment.
Topics: Adult; Androgens; Arginine; Blood Glucose; Body Mass Index; C-Reactive Protein; Cholesterol, LDL; Cross-Sectional Studies; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Metformin; Polycystic Ovary Syndrome; Statistics, Nonparametric; Triglycerides; Waist-Hip Ratio | 2008 |
Polycystic ovarian syndrome, biomarkers, and metformin: research, risk, and reality.
Topics: Arginine; Female; Humans; Hypoglycemic Agents; Metformin; Polycystic Ovary Syndrome; Risk Factors | 2008 |
Metformin and oral contraceptive treatments reduced circulating asymmetric dimethylarginine (ADMA) levels in patients with polycystic ovary syndrome (PCOS).
Topics: Adult; Androgens; Arginine; Body Mass Index; Case-Control Studies; Contraceptives, Oral; Cyproterone Acetate; Ethinyl Estradiol; Female; Gonadotropins; Humans; Insulin Resistance; Metformin; Polycystic Ovary Syndrome; Time Factors | 2008 |
Effects of cross-link breakers, glycation inhibitors and insulin sensitisers on HDL function and the non-enzymatic glycation of apolipoprotein A-I.
Topics: Apolipoprotein A-I; Arginine; Cross-Linking Reagents; Glycosylation; Guanidines; Humans; Lipoproteins, HDL; Lysine; Metformin; Phosphatidylcholine-Sterol O-Acyltransferase; Pyridoxamine; Pyruvaldehyde; Thiazoles; Tryptophan | 2008 |
Beneficial endocrine but adverse exocrine effects of sitagliptin in the human islet amyloid polypeptide transgenic rat model of type 2 diabetes: interactions with metformin.
Topics: Amyloid; Animals; Animals, Genetically Modified; Arginine; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucose Clamp Technique; Humans; Hyperglycemia; Hyperinsulinism; Hypoglycemic Agents; Islet Amyloid Polypeptide; Islets of Langerhans; Metformin; Pyrazines; Rats; Rats, Sprague-Dawley; Sitagliptin Phosphate; Triazoles | 2009 |
Increased glycation and oxidative damage to apolipoprotein B100 of LDL cholesterol in patients with type 2 diabetes and effect of metformin.
Topics: Aged; Apolipoprotein B-100; Arginine; Blood Pressure; Cholesterol; Cholesterol, LDL; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Hypoglycemic Agents; Lipoproteins; Lipoproteins, LDL; Male; Metformin; Middle Aged; Reference Values | 2010 |
Genetic polymorphisms in organic cation transporter 1 (OCT1) in Chinese and Japanese populations exhibit altered function.
Topics: Aged; Arginine; Biological Transport, Active; Biotinylation; Blotting, Western; Cell Line; China; Diabetes Mellitus, Type 2; DNA; Female; Flow Cytometry; Genetic Variation; Genotype; Green Fluorescent Proteins; Humans; Hypoglycemic Agents; Japan; Kinetics; Male; Metformin; Middle Aged; Organic Cation Transporter 1; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Sequence Alignment | 2010 |
Interaction of the cardiovascular risk marker asymmetric dimethylarginine (ADMA) with the human cationic amino acid transporter 1 (CAT1).
Topics: Arginine; Biological Transport; Biomarkers; Cardiovascular Diseases; Cationic Amino Acid Transporter 1; Gene Expression; HEK293 Cells; Humans; Kinesics; Metformin; Risk | 2012 |
Metformin reduces asymmetric dimethylarginine and prevents hypertension in spontaneously hypertensive rats.
Topics: Amidohydrolases; Animals; Arginine; Blood Pressure; Body Weight; Hypertension; Kidney; Lung; Male; Metformin; Nitric Oxide; Rats, Inbred SHR; Rats, Inbred WKY | 2014 |
Antidiabetic drug metformin is effective on the metabolism of asymmetric dimethylarginine in experimental liver injury.
Topics: Alanine Transaminase; Amidohydrolases; Animals; Arginine; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Galactosamine; Glutathione; Hypoglycemic Agents; Lipopolysaccharides; Male; Metformin; Peroxidase; Protective Agents; Rats; Rats, Sprague-Dawley | 2014 |
Plasma Levels of Pentosidine, Carboxymethyl-Lysine, Soluble Receptor for Advanced Glycation End Products, and Metabolic Syndrome: The Metformin Effect.
Topics: Adult; Arginine; Biomarkers; Case-Control Studies; Diabetes Mellitus, Type 2; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Humans; Hypoglycemic Agents; Lysine; Male; Metabolic Syndrome; Metformin; Middle Aged; Prognosis; Receptor for Advanced Glycation End Products | 2016 |
Lack of Durable Improvements in β-Cell Function Following Withdrawal of Pharmacological Interventions in Adults With Impaired Glucose Tolerance or Recently Diagnosed Type 2 Diabetes.
Topics: Adult; Arginine; B-Lymphocytes; Blood Glucose; Body Weight; C-Peptide; Diabetes Mellitus, Type 2; Fasting; Female; Glucose Intolerance; Humans; Hypoglycemic Agents; Insulin Glargine; Insulin Resistance; Liraglutide; Male; Metformin; Middle Aged; Withholding Treatment | 2019 |
Cholecalciferol and metformin protect against lipopolysaccharide-induced endothelial dysfunction and senescence by modulating sirtuin-1 and protein arginine methyltransferase-1.
Topics: Antioxidants; Arginine; Cell Cycle Checkpoints; Cell Line; Cellular Senescence; Cholecalciferol; Endothelium; Homocysteine; Humans; Lipopolysaccharides; Metformin; Methylation; NAD; Nitric Oxide; Protective Agents; Protein-Arginine N-Methyltransferases; Repressor Proteins; S-Adenosylmethionine; Sirtuin 1; Telomerase; Vitamin D Response Element | 2021 |
Metformin encapsulated gold nanoparticles (MTF-GNPs): A promising antiglycation agent.
Topics: Arginine; Diabetes Mellitus, Type 2; Glycation End Products, Advanced; Gold; Humans; Hypoglycemic Agents; Lysine; Metal Nanoparticles; Metformin; Ribose; Serum Albumin, Bovine | 2022 |
Carbonized polymer dots derived from metformin and L-arginine for tumor cell membrane- and mitochondria-dual targeting therapy.
Topics: Apoptosis; Arginine; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Humans; Lung Neoplasms; Metformin; Mitochondria; Reactive Oxygen Species | 2023 |