arginine and guanosine triphosphate

arginine has been researched along with guanosine triphosphate in 102 studies

Research

Studies (102)

TimeframeStudies, this research(%)All Research%
pre-199022 (21.57)18.7374
1990's26 (25.49)18.2507
2000's38 (37.25)29.6817
2010's12 (11.76)24.3611
2020's4 (3.92)2.80

Authors

AuthorsStudies
Colman, RF; Pal, PK1
Izui, K; Kameshita, I; Katsuki, H; Tokushige, M1
Heizmann, P; Howell, SH1
Rochovansky, O1
Laustiola, KE; Manninen, V; Metsä-Ketelä, T; Pörsti, I; Vapaatalo, H; Vuorinen, P1
Deguchi, T; Fujimori, H; Inamura, K; Ishikawa, F; Kosasayama, A; Masayasu, H; Suzuki, K; Yoshioka, M1
Christian, E; Illangesekare, M; Yarus, M1
Dong, Q; Fromm, HJ; Liu, F; Myers, AM1
Christian, EL; Hicke, BJ; Yarus, M1
Freissmuth, M; Gilman, AG1
Yarus, M2
Cech, TR; Levine, J; Morin, GB; Yarus, M1
Federn, H; Ristow, H1
Fujiwara, M; Kamiya, T; Narumiya, S; Ohashi, Y1
Howell, SL; Montague, W1
Birnbaumer, L; Yang, PC1
Birnbaumer, L; Nakahara, T; Yang, PC1
Ofengand, J1
Gallant, J; Margason, G1
Barrett, J1
Kaji, H; Tanaka, Y1
Blethen, SL1
Carta, F; Maraini, G; Pescatori, A; Prosperi, L1
Kassab, R; Pradel, LA; Roustan, C; Van Thoai, N1
de Nó, C; Hernández, F; Palacián, E1
Berghuis, AM; Coleman, DE; Gilman, AG; Lee, E; Linder, ME; Sprang, SR1
Lee, YH; Lin, K; Okar, D; Pilkis, SJ1
Brownbridge, GG; Lowe, PN; Moore, KJ; Skinner, RH; Webb, MR1
Rikkonen, M1
Demeure, MJ; Doffek, KM; Gorski, J; Komorowski, RA1
Clark, BF; Knudsen, CR1
Bourne, HR; Farfel, Z; Iiri, T1
Amin, RH; Bondarenko, VA; Desai, M; Dua, S; Hayashi, F; Jackson, KW; Kinumi, T; Komori, N; Lipkin, VM; Matsumoto, H; Ohashi, M; Usukura, J; Yamazaki, A; Yamazaki, M; Yousif, KK1
Eccleston, JF; Gamblin, SJ; Laue, E; Nurmahomed, K; Owen, D; Rittinger, K; Smerdon, SJ; Walker, PA1
Ehrenfeld, E; Richards, OC1
Ahmadian, MR; Scheffzek, K; Stege, P; Wittinghofer, A1
Bourne, HR1
Clark, BF; Knudsen, CR; Nautrup Pedersen, G; Rattenborg, T1
Eccleston, JF; Graham, DL; Lowe, PN1
Moss, J; Vaughan, M; Vitale, N1
Gamblin, SJ; Rittinger, K; Smerdon, SJ; Taylor, WR1
Daniel, DS; Dickey, BF; Hoffenberg, S; Nichols, JC; Nikolova, L; Soman, K1
Goldberg, J1
Kemp, RG; Wang, X1
Barbieri, JT; Ganesan, AK; Olson, JC; Vincent, TS1
Koyama, T; Nakagawa, S; Nishi, N; Odagaki, Y1
Mohr, D; Rodnina, MV; Savelsbergh, A; Wilden, B; Wintermeyer, W1
Tabancay, AP; Tamanoi, F; Urano, J; Yang, W1
Cassel, D; Huber, I; Pick, E; Rotman, M; Szafer, E; Zuck, S1
Clabecq, A; Darchen, F; Henry, JP1
Mohr, D; Rodnina, MV; Wintermeyer, W1
Brannetti, B; Ferrè, F; Helmer-Citterich, M; Valencia, A; Via, A1
Bienengraeber, M; Echtay, KS; Klingenberg, M1
Dixon, DA; Miller, JH; Resat, H; Straatsma, TP1
Daitoku, H; Fujiwara, K; Fukamizu, A; Isida, J; Nakajima, T1
Chen, C; Chou, CC; Forouhar, F; Hsiao, CD; Kao, S; Li Hm, HM; Shr, HL; Sun, YJ; Tu, SL; Yeh, YH1
Körner, C; Seewald, MJ; Vetter, IR; Wittinghofer, A1
Banchelli, G; Matucci, R; Pirisino, R; Raimondi, L; Stillitano, F1
Karpusas, M; Plaitakis, A; Spanaki, C; Zaganas, I1
Cerione, RA; Fidyk, NJ1
Willemoës, M1
Bearne, SL; Hewitt, KA; Iyengar, A; Lunn, F; Simard, D1
Downs, MA; Hargrave, PA; Kisselev, OG; McDowell, JH1
Bunster, M; Hinrichs, MV; Montecino, M; Olate, J1
Ashikaga, T; Kishi, Y; Numano, F; Watanabe, R1
Arnold, E; Ding, J; Guan, K; Li, S; Li, Y; Xu, X; Yu, Y1
Armengod, ME; Björk, GR; Martínez-Vicente, M; Mellado, M; Pérez-Payá, E; Villarroya, M; Yim, L1
Iguchi, N; Isotani, A; Kitamura, K; Maekawa, M; Masai, K; Matsuoka, Y; Nishimune, Y; Okabe, M; Onishi, M; Tanaka, H; Toshimori, K; Toyama, Y1
Cerione, RA; Pereira, R1
Brack-Werner, R; Devaux, C; Fridkin, G; Gilon, C; Hariton-Gazal, E; Loyter, A; Rosenbluh, J; Wolff, H; Zakai, N1
Becker, A; Eschenburg, S; Kull, FJ; Leonard, M; Manstein, DJ; Reubold, TF; Schmid, SL; Vallee, RB1
Cerione, RA; Majumdar, S; Ramachandran, S1
Brownie, ER; Fraser, ME; Hayakawa, K; Hume, MS; Ryan, DG1
Ghosh, A; Herrmann, C; Praefcke, GJ; Renault, L; Wittinghofer, A1
Begg, GE; Graham, RM; Holman, SR; Iismaa, SE; Matthews, JM; Stokes, PH1
Begg, GE; Carrington, L; Graham, RM; Husain, A; Iismaa, SE; Lorand, L; Matthews, JM; Stokes, PH; Wouters, MA1
Bange, G; Parlitz, RO; Petzold, G; Sinning, I; Wild, K1
Gerwert, K; Schlitter, J; te Heesen, H1
Deaconescu, D; Scrima, A; Thomas, C; Wittinghofer, A1
Marco-Marín, C; Rubio, V1
Beauchamp, BB; Crampton, DJ; Richardson, CC; Satapathy, AK1
Du, X; Sprang, SR1
Lushington, GH; Mou, TC; Pinto, C; Richter, M; Seifert, R; Suryanarayana, S1
Chou, KC; Wang, JF1
Haber, M; Iismaa, SE; Liu, PY; Liu, T; Marshall, GM; Norris, MD; Tee, AEL; Xu, N1
Farquhar, MG; Garcia-Marcos, M; Ghosh, P1
Hot, E; Keilberg, D; Koerner, C; Leonardy, S; Miertzschke, M; Søgaard-Andersen, L; Vetter, IR; Wittinghofer, A1
Herrmann, C; Kunzelmann, S; Wehner, M1
Kotsiuruba, AV; Moĭbenko, OO; Neshcheret, OP; Rovenets', RA; Strutyns'kyĭ, RB1
Anand, B; Majumdar, S; Prakash, B1
Jeganathan, A; Ortega, J; Razi, A; Thurlow, B1
Jang, H; Lu, S; Nussinov, R; Zhang, J1
Feng, W; Kong, R; Lou, J; Ren, J; Wu, JY; Yi, F; Zhu, L1
Acharya, A; Majumdar, S; Prakash, B1
Chandra, M; Datta, S; Kotyada, C; Narooka, AR; Tripathi, A; Verma, A1
Gu, X; Sabatini, DM; Shen, K; Valenstein, ML1
Garcia, AE; Ngo, VA1
Gong, P; Jia, H; Peng, C; Zhong, Y1
Neale, C; Patel, LA; Stephen, AG; Waybright, TJ1
Bazer, FW; Burghardt, RC; Johnson, GA; Li, X; Wu, G1
Bergman, AM; Jensen, PB; Munch-Petersen, B; Peters, GJ; Pinedo, HM; Sehested, M; Smid, K; Veerman, G; Voorn, DA1

Other Studies

102 other study(ies) available for arginine and guanosine triphosphate

ArticleYear
The importance of arginine residues in the catalytic and regulatory functions of bovine-liver glutamate dehydrogenase.
    European journal of biochemistry, 1976, Sep-15, Volume: 68, Issue:2

    Topics: Adenosine Diphosphate; Allosteric Regulation; Allosteric Site; Arginine; Butanones; Glutamate Dehydrogenase; Guanosine Triphosphate; Kinetics; Liver; NAD; Protein Binding

1976
Reversible desensitization of phosphoenolpyruvate carboxylase to multiple effectors by butanedione.
    Biochemical and biophysical research communications, 1977, Jun-06, Volume: 76, Issue:3

    Topics: Acetyl Coenzyme A; Allosteric Site; Arginine; Aspartic Acid; Binding Sites; Borates; Butanones; Diacetyl; Escherichia coli; Guanosine Triphosphate; Kinetics; Lactates; Lauric Acids; Magnesium; Phosphoenolpyruvate Carboxykinase (GTP)

1977
Synthesis of ppGpp and chloroplast ribosomal RNA in Chlamydomonas reinhardi.
    Biochimica et biophysica acta, 1978, Jan-26, Volume: 517, Issue:1

    Topics: Arginine; Chlamydomonas; Chloroplasts; Cycloheximide; Cytoplasm; Guanine Nucleotides; Guanosine Tetraphosphate; Guanosine Triphosphate; Mutation; RNA, Ribosomal

1978
On the role of substrate and GTP in the regulation of argininosuccinase activity.
    The Journal of biological chemistry, 1975, Sep-25, Volume: 250, Issue:18

    Topics: Animals; Arginine; Argininosuccinate Lyase; Argininosuccinic Acid; Binding Sites; Cattle; Guanosine Triphosphate; Kinetics; Liver; Lyases; Macromolecular Substances; Molecular Weight; Osmolar Concentration; Phosphates; Protein Binding; Tromethamine

1975
Endothelium-dependent and -independent effects of exogenous ATP, adenosine, GTP and guanosine on vascular tone and cyclic nucleotide accumulation of rat mesenteric artery.
    British journal of pharmacology, 1992, Volume: 105, Issue:2

    Topics: Acetylcholine; Adenosine; Adenosine Triphosphate; Animals; Arginine; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Guanosine; Guanosine Triphosphate; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Relaxation; Muscle Tonus; Muscle, Smooth, Vascular; Nitroarginine; Nucleotides; Rats; Rats, Inbred Strains

1992
Effects of arginine derivatives on soluble guanylate cyclase from neuroblastoma N1E 115 cells.
    Biochemical pharmacology, 1990, Jan-01, Volume: 39, Issue:1

    Topics: Arginine; Binding, Competitive; Dansyl Compounds; Guanosine Triphosphate; Guanylate Cyclase; Magnesium; Molecular Structure; Neuroblastoma; Structure-Activity Relationship; Tumor Cells, Cultured

1990
Selection of small molecules by the Tetrahymena catalytic center.
    Nucleic acids research, 1991, Mar-25, Volume: 19, Issue:6

    Topics: Amino Acids; Animals; Arginine; Base Sequence; Catalysis; Chromatography, Liquid; Guanosine Triphosphate; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; RNA Splicing; RNA, Protozoan; Substrate Specificity; Tetrahymena

1991
Evidence for an arginine residue at the substrate binding site of Escherichia coli adenylosuccinate synthetase as studied by chemical modification and site-directed mutagenesis.
    The Journal of biological chemistry, 1991, Jul-05, Volume: 266, Issue:19

    Topics: Adenylosuccinate Synthase; Amino Acid Sequence; Arginine; Base Sequence; Binding Sites; Chromatography, High Pressure Liquid; Escherichia coli; Guanosine Triphosphate; Inosine Monophosphate; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Mapping; Phenylglyoxal; Trypsin

1991
Stereoselective arginine binding is a phylogenetically conserved property of group I self-splicing RNAs.
    The EMBO journal, 1989, Dec-01, Volume: 8, Issue:12

    Topics: Amino Acids; Ammonium Chloride; Arginine; Base Sequence; Binding, Competitive; Guanosine Triphosphate; Introns; Kinetics; Molecular Sequence Data; Neurospora; Neurospora crassa; Nucleic Acid Conformation; Osmolar Concentration; Phylogeny; RNA Splicing; RNA, Catalytic; RNA, Fungal; RNA, Ribosomal; Stereoisomerism

1989
Mutations of GS alpha designed to alter the reactivity of the protein with bacterial toxins. Substitutions at ARG187 result in loss of GTPase activity.
    The Journal of biological chemistry, 1989, Dec-25, Volume: 264, Issue:36

    Topics: Adenylate Cyclase Toxin; Animals; Arginine; Binding Sites; Cholera Toxin; DNA; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Kinetics; Mutation; NAD; Pertussis Toxin; Phosphoric Monoester Hydrolases; Protein Binding; Recombinant Proteins; Restriction Mapping; Thionucleotides; Virulence Factors, Bordetella

1989
Specificity of arginine binding by the Tetrahymena intron.
    Biochemistry, 1989, Feb-07, Volume: 28, Issue:3

    Topics: Animals; Arginine; Binding, Competitive; Guanosine Triphosphate; Introns; Kinetics; Models, Molecular; RNA Precursors; RNA Splicing; RNA, Catalytic; RNA, Ribosomal; Structure-Activity Relationship; Tetrahymena; Transcription, Genetic

1989
A Tetrahymena intron nucleotide connected to the GTP/arginine site.
    Nucleic acids research, 1989, Sep-12, Volume: 17, Issue:17

    Topics: Animals; Arginine; Base Sequence; Binding Sites; Guanosine Triphosphate; Introns; Molecular Sequence Data; Nucleic Acid Conformation; RNA Precursors; RNA Splicing; RNA, Catalytic; RNA, Ribosomal; Tetrahymena

1989
The GTP pool in Bacillus brevis and its significance for sporulation.
    European journal of biochemistry, 1987, May-15, Volume: 165, Issue:1

    Topics: Adenine Nucleotides; Arginine; Bacillus; Energy Metabolism; Guanine Nucleotides; Guanosine Triphosphate; Kinetics; Spores, Bacterial; Threonine; Tyrocidine

1987
A specific amino acid binding site composed of RNA.
    Science (New York, N.Y.), 1988, Jun-24, Volume: 240, Issue:4860

    Topics: Animals; Arginine; Binding Sites; Catalysis; Genetic Code; Guanosine Triphosphate; Kinetics; Magnesium; Models, Molecular; RNA Splicing; RNA, Ribosomal; Structure-Activity Relationship; Tetrahymena

1988
ADP-ribosylation by type C1 and D botulinum neurotoxins: stimulation by guanine nucleotides and inhibition by guanidino-containing compounds.
    Biochemical and biophysical research communications, 1987, Feb-13, Volume: 142, Issue:3

    Topics: Adenosine Diphosphate Ribose; Agmatine; Animals; Arginine; Botulinum Toxins; Brain; Guanidines; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Mice; Molecular Weight; Toxoids

1987
Adenylate cyclase activity in isolated rat islets of Langerhans. Effects of agents which alter rates of insulin secretion.
    Biochimica et biophysica acta, 1973, Aug-17, Volume: 320, Issue:1

    Topics: Adenylyl Cyclases; Animals; Arginine; Epinephrine; Fluorides; Glucagon; Glucose; Glyburide; Guanosine Triphosphate; Hydrogen-Ion Concentration; In Vitro Techniques; Islets of Langerhans; Isoproterenol; Kinetics; Leucine; Male; Norepinephrine; Nucleotides; Phenoxybenzamine; Phosphorus Radioisotopes; Potassium; Propranolol; Prostaglandins; Rats; Xylitol

1973
Studies on receptor-mediated activation of adenylyl cyclases. I. Preparation and description of general properties of an adenylyl cyclase system in beef renal medullary membranes sensitive to neurohypophyseal hormones.
    The Journal of biological chemistry, 1974, Dec-25, Volume: 249, Issue:24

    Topics: Adenylyl Cyclases; Animals; Arginine; Cattle; Cell Membrane; Centrifugation, Density Gradient; Chromatography, Ion Exchange; Chromatography, Thin Layer; Cyclic AMP; Enzyme Activation; Guanosine Triphosphate; Kidney; Kidney Medulla; Kinetics; Lysine; Microscopy, Phase-Contrast; Oxytocin; Phosphorus Radioisotopes; Receptors, Cell Surface; Subcellular Fractions; Time Factors; Tritium; Vasopressins

1974
Studies on receptor-mediated activation of adenylyl cyclases. II. Nucleotide and nucleoside regulation of the activities of the beef renal medullary adenylyl cyclase and their stimulation by neurohypophyseal hormones.
    The Journal of biological chemistry, 1974, Dec-25, Volume: 249, Issue:24

    Topics: Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Allosteric Regulation; Animals; Arginine; Cattle; Cell Membrane; Enzyme Activation; Guanosine Triphosphate; Hydrogen-Ion Concentration; Kidney; Kidney Medulla; Kinetics; Manganese; Oxytocin; Phosphorus Radioisotopes; Pituitary Hormones, Posterior; Receptors, Cell Surface; Ribonucleotides; Time Factors; Vasopressins

1974
Assay for AA-tRNA recognition by the EFTu-GTP complex of Escherichia coli.
    Methods in enzymology, 1974, Volume: 29

    Topics: Amino Acids; Arginine; Binding Sites; Binding, Competitive; Escherichia coli; Evaluation Studies as Topic; Fluorouracil; Guanosine Triphosphate; Kinetics; Methionine; Methods; Peptide Elongation Factors; Phenylalanine; Protein Binding; RNA, Bacterial; RNA, Transfer; Time Factors; Tryptophan; Valine

1974
Amino acid control of messenger ribonucleic acid synthesis in Bacillus subtilis.
    The Journal of biological chemistry, 1972, Apr-25, Volume: 247, Issue:8

    Topics: Adenine; Adenosine Triphosphate; Amino Acids; Arginine; Bacillus subtilis; Chromatography, Thin Layer; Culture Media; Genetics, Microbial; Guanine Nucleotides; Guanosine Triphosphate; Mutation; Phosphoric Acids; Phosphorus Isotopes; RNA, Bacterial; RNA, Messenger; Tritium

1972
Nucleoside triphosphate metabolism in the muscle tissue of Ascaris lumbricoides (Nematoda).
    International journal for parasitology, 1973, Volume: 3, Issue:3

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Aminohydrolases; Animals; Arginine; Ascaris; Chromatography, Thin Layer; Creatine; Creatine Kinase; Female; Guanine Nucleotides; Guanosine Triphosphate; Inosine Nucleotides; Muscles; Phosphates; Phosphotransferases; Ribonucleotides; Swine; Uridine Diphosphate Sugars

1973
Incorporation of arginine by soluble extracts of ascites tumor cells and regenerating rat liver.
    Cancer research, 1974, Volume: 34, Issue:9

    Topics: Adenosine Triphosphate; Amino Acyl-tRNA Synthetases; Animals; Arginine; Carbon Radioisotopes; Carcinoma, Ehrlich Tumor; Cell-Free System; Centrifugation, Density Gradient; Guanosine Triphosphate; Hepatectomy; Liver; Liver Regeneration; Neoplasm Proteins; Puromycin; Rats; Ribonucleases; Ribosomes; RNA, Transfer; Time Factors

1974
Kinetic properties of the arginine kinase isoenzymes of Limulus polyphemus.
    Archives of biochemistry and biophysics, 1972, Volume: 149, Issue:1

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arginine; Brachyura; Calcium; Canavanine; Carbon Isotopes; Chromatography, Thin Layer; Enzyme Activation; Guanidines; Guanosine Triphosphate; Inosine Nucleotides; Isoenzymes; Kinetics; Magnesium; Manganese; Models, Chemical; Phosphotransferases; Stereoisomerism; Structure-Activity Relationship; Valerates

1972
Protein metabolism in human senile cataract.
    Experimental eye research, 1971, Volume: 11, Issue:1

    Topics: Adenosine Triphosphate; Aged; Amino Acids; Animals; Arginine; Aspartic Acid; Biological Transport; Cataract; Crystallins; Guanosine Triphosphate; Humans; Lens, Crystalline; Leucine; Rabbits; Tritium

1971
Studies on the partial exchange and overall reactions catalyzed by native and modified arginine kinase from Homarus vulgaris muscle.
    Biochimica et biophysica acta, 1971, Volume: 250, Issue:1

    Topics: Adenine Nucleotides; Alkylation; Animals; Annelida; Arginine; Binding Sites; Carbon Isotopes; Catalysis; Chemical Phenomena; Chemistry; Chromatography, Paper; Creatine Kinase; Cysteine; Dansyl Compounds; Guanosine Triphosphate; Histidine; Kinetics; L-Lactate Dehydrogenase; Lysine; Muscles; Nephropidae; Phosphotransferases; Protein Binding; Pyruvate Kinase; Rabbits

1971
Functional implication of the sole arginine residue of ribosomal proteins L7/L12.
    Molecular biology reports, 1984, Volume: 10, Issue:2

    Topics: Amino Acid Sequence; Arginine; Bacterial Proteins; Escherichia coli; Guanosine Diphosphate; Guanosine Triphosphate; Peptide Biosynthesis; Peptides; Ribosomal Proteins

1984
Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis.
    Science (New York, N.Y.), 1994, Sep-02, Volume: 265, Issue:5177

    Topics: Aluminum Compounds; Arginine; Binding Sites; Catalysis; Computer Graphics; Crystallography, X-Ray; Fluorides; Glutamine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Helix-Loop-Helix Motifs; Hydrogen Bonding; Hydrolysis; Models, Molecular; Protein Conformation; Protein Structure, Secondary

1994
Mechanism of modulation of rat liver fructose-2,6-bisphosphatase by nucleoside triphosphates.
    The Journal of biological chemistry, 1994, Apr-15, Volume: 269, Issue:15

    Topics: Adenosine Triphosphate; Alanine; Amino Acid Sequence; Animals; Arginine; Chromatography, Gel; Electrophoresis, Polyacrylamide Gel; Guanosine Triphosphate; Kinetics; Liver; Lysine; Molecular Weight; Mutagenesis, Site-Directed; Phosphofructokinase-2; Phosphoric Monoester Hydrolases; Point Mutation; Rats; Recombinant Proteins; Sequence Deletion

1994
Interaction of GTPase activating proteins (GAPs) with p21ras measured by a novel fluorescence anisotropy method. Essential role of Arg-903 of GAP in activation of GTP hydrolysis on p21ras.
    The Journal of biological chemistry, 1993, May-25, Volume: 268, Issue:15

    Topics: Amino Acid Sequence; Arginine; Escherichia coli; Fluorescence Polarization; GTPase-Activating Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Kinetics; Macromolecular Substances; Mathematics; Models, Biological; Mutagenesis, Site-Directed; Proteins; Proto-Oncogene Proteins p21(ras); ras GTPase-Activating Proteins; Recombinant Proteins

1993
Functional significance of the nuclear-targeting and NTP-binding motifs of Semliki Forest virus nonstructural protein nsP2.
    Virology, 1996, Apr-15, Volume: 218, Issue:2

    Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Arginine; Base Sequence; Binding Sites; Cell Line; Cell Nucleus; Cricetinae; Cytoplasm; DNA; Female; Guanosine Triphosphate; Lysine; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Mutation; Protein Biosynthesis; Semliki forest virus; Viral Nonstructural Proteins; Virus Replication

1996
Gip-2 codon 179 oncogene mutations: absent in adrenal cortical tumors.
    World journal of surgery, 1996, Volume: 20, Issue:7

    Topics: Adenoma; Adrenal Cortex Neoplasms; Arginine; Base Sequence; Carcinoma; Codon; Cysteine; DNA Restriction Enzymes; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Proteins; Guanosine Triphosphate; Histidine; Humans; Molecular Sequence Data; Oncogenes; Point Mutation; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length

1996
Site-directed mutagenesis of Arg58 and Asp86 of elongation factor Tu from Escherichia coli: effects on the GTPase reaction and aminoacyl-tRNA binding.
    Protein engineering, 1995, Volume: 8, Issue:12

    Topics: Anti-Bacterial Agents; Arginine; Aspartic Acid; Base Sequence; DNA Primers; Escherichia coli; GTP Phosphohydrolase-Linked Elongation Factors; Guanosine Diphosphate; Guanosine Triphosphate; Kinetics; Models, Molecular; Molecular Sequence Data; Molecular Structure; Mutagenesis, Site-Directed; Peptide Elongation Factor Tu; Protein Binding; Pyridones; Recombinant Proteins; Ribosomes; RNA, Transfer; RNA, Transfer, Phe

1995
Conditional activation defect of a human Gsalpha mutant.
    Proceedings of the National Academy of Sciences of the United States of America, 1997, May-27, Volume: 94, Issue:11

    Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Arginine; Cell Line; Conserved Sequence; Cyclic AMP; Glutamic Acid; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Humans; Isoproterenol; Kinetics; Macromolecular Substances; Models, Molecular; Mutagenesis, Site-Directed; Point Mutation; Protein Conformation; Receptors, Adrenergic, beta-2; Recombinant Fusion Proteins; Spodoptera; Transfection

1997
Residues within the polycationic region of cGMP phosphodiesterase gamma subunit crucial for the interaction with transducin alpha subunit. Identification by endogenous ADP-ribosylation and site-directed mutagenesis.
    The Journal of biological chemistry, 1997, Jun-20, Volume: 272, Issue:25

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Adenosine Diphosphate Ribose; Animals; Arginine; Binding Sites; Cattle; Cyclic Nucleotide Phosphodiesterases, Type 6; GTP Phosphohydrolases; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Mutagenesis, Site-Directed; NAD; Pertussis Toxin; Rana catesbeiana; Recombinant Proteins; Transducin; Virulence Factors, Bordetella

1997
Crystal structure of a small G protein in complex with the GTPase-activating protein rhoGAP.
    Nature, 1997, Aug-14, Volume: 388, Issue:6643

    Topics: Arginine; cdc42 GTP-Binding Protein; Cell Cycle Proteins; Crystallography, X-Ray; Enzyme Activation; GTP Phosphohydrolases; GTP-Binding Proteins; GTPase-Activating Proteins; Guanosine Triphosphate; Models, Molecular; Protein Conformation

1997
One of two NTP binding sites in poliovirus RNA polymerase required for RNA replication.
    The Journal of biological chemistry, 1997, Sep-12, Volume: 272, Issue:37

    Topics: Arginine; Binding Sites; Borohydrides; Cross-Linking Reagents; Cyanogen Bromide; Guanosine Triphosphate; Leucine; Lysine; Nucleotides; Peptide Fragments; Poliovirus; RNA-Dependent RNA Polymerase; RNA, Viral

1997
Confirmation of the arginine-finger hypothesis for the GAP-stimulated GTP-hydrolysis reaction of Ras.
    Nature structural biology, 1997, Volume: 4, Issue:9

    Topics: Arginine; Binding Sites; GTP Phosphohydrolases; GTPase-Activating Proteins; Guanosine Triphosphate; Proteins; ras GTPase-Activating Proteins; ras Proteins

1997
G proteins. The arginine finger strikes again.
    Nature, 1997, Oct-16, Volume: 389, Issue:6652

    Topics: Arginine; GTP Phosphohydrolases; GTP-Binding Proteins; GTPase-Activating Proteins; Guanosine Triphosphate; Hydrolysis; Protein Binding; Protein Conformation; Proteins; RGS Proteins; rhoA GTP-Binding Protein; Signal Transduction

1997
Contribution of Arg288 of Escherichia coli elongation factor Tu to translational functionality.
    European journal of biochemistry, 1997, Oct-15, Volume: 249, Issue:2

    Topics: Amino Acid Sequence; Amino Acid Substitution; Arginine; Asparagine; Binding Sites; Conserved Sequence; Escherichia coli; GTP Phosphohydrolase-Linked Elongation Factors; Guanosine Diphosphate; Guanosine Triphosphate; Hydrogen Bonding; Kinetics; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Peptide Elongation Factor Tu; Protein Conformation; Recombinant Proteins; Ribosomes; RNA, Transfer, Phe; Thermus

1997
Characterisation of the interaction of normal and mutant Rho-GAP with Rho family proteins.
    Biochemical Society transactions, 1997, Volume: 25, Issue:3

    Topics: Amino Acid Sequence; Arginine; Conserved Sequence; GTP Phosphohydrolases; GTP-Binding Proteins; GTPase-Activating Proteins; Guanosine Triphosphate; Kinetics; Mutagenesis, Site-Directed; Proteins; rac GTP-Binding Proteins; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid

1997
Molecular characterization of the GTPase-activating domain of ADP-ribosylation factor domain protein 1 (ARD1).
    The Journal of biological chemistry, 1998, Jan-30, Volume: 273, Issue:5

    Topics: Arginine; DNA Mutational Analysis; GTP Phosphohydrolases; GTP-Binding Proteins; GTPase-Activating Proteins; Guanosine Triphosphate; Hydrolysis; Protein Binding; Proteins; Recombinant Fusion Proteins; Zinc Fingers

1998
Support for shared ancestry of GAPs.
    Nature, 1998, Apr-02, Volume: 392, Issue:6675

    Topics: Arginine; Binding Sites; Evolution, Molecular; GTPase-Activating Proteins; Guanosine Triphosphate; Protein Conformation; Proteins; ras GTPase-Activating Proteins; ras Proteins; Signal Transduction

1998
Conformationally variable Rab protein surface regions mapped by limited proteolysis and homology modelling.
    The Biochemical journal, 1998, Dec-01, Volume: 336 ( Pt 2)

    Topics: Amino Acid Sequence; Arginine; Binding Sites; Conserved Sequence; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Mass Spectrometry; Models, Molecular; Molecular Sequence Data; Protein Conformation; rab4 GTP-Binding Proteins; rab5 GTP-Binding Proteins; Sequence Analysis; Sequence Homology, Amino Acid; Trypsin

1998
Structural and functional analysis of the ARF1-ARFGAP complex reveals a role for coatomer in GTP hydrolysis.
    Cell, 1999, Mar-19, Volume: 96, Issue:6

    Topics: ADP-Ribosylation Factor 1; ADP-Ribosylation Factors; Amino Acid Sequence; Animals; Arginine; Coatomer Protein; GTP Phosphohydrolases; GTP-Binding Proteins; GTPase-Activating Proteins; Guanosine Triphosphate; Humans; Hydrolysis; Membrane Proteins; Molecular Sequence Data; Protein Conformation; Proteins; ras GTPase-Activating Proteins; ras Proteins; Rats; Sequence Homology, Amino Acid; Structure-Activity Relationship

1999
Identification of residues of Escherichia coli phosphofructokinase that contribute to nucleotide binding and specificity.
    Biochemistry, 1999, Apr-06, Volume: 38, Issue:14

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Amino Acids; Arginine; Binding Sites; Cytidine Triphosphate; Escherichia coli; Guanosine Triphosphate; Inosine Triphosphate; Models, Molecular; Mutagenesis, Site-Directed; Phenylalanine; Phosphofructokinase-1; Substrate Specificity; Tyrosine; Uridine Triphosphate

1999
Pseudomonas aeruginosa exoenzyme S disrupts Ras-mediated signal transduction by inhibiting guanine nucleotide exchange factor-catalyzed nucleotide exchange.
    The Journal of biological chemistry, 1999, Jul-30, Volume: 274, Issue:31

    Topics: Adenosine Diphosphate; Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Arginine; Bacterial Toxins; Cell Cycle Proteins; Cell Line; Coculture Techniques; Guanosine Triphosphate; Kinetics; Mammals; Pseudomonas aeruginosa; ras Proteins; ras-GRF1; Recombinant Fusion Proteins; Signal Transduction; Transfection

1999
Activation of G proteins by neuropeptide Y and gamma-aminobutyric acid(B) receptor agonists in rat cerebral cortical membranes through distinct modes of action.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:3

    Topics: Animals; Arginine; Biotransformation; Cell Membrane; Cerebral Cortex; GABA-B Receptor Agonists; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Triphosphate; Magnesium Chloride; Male; Neuropeptide Y; Peptides; Rats; Rats, Sprague-Dawley; Receptors, Neuropeptide Y; Stimulation, Chemical

1999
Stimulation of the GTPase activity of translation elongation factor G by ribosomal protein L7/12.
    The Journal of biological chemistry, 2000, Jan-14, Volume: 275, Issue:2

    Topics: Amino Acid Substitution; Arginine; GTP Phosphohydrolases; Guanosine Triphosphate; Kinetics; Methionine; Mutagenesis, Site-Directed; Peptide Elongation Factor G; Recombinant Proteins; Ribosomal Proteins; RNA, Transfer, Phe

2000
The Saccharomyces cerevisiae Rheb G-protein is involved in regulating canavanine resistance and arginine uptake.
    The Journal of biological chemistry, 2000, Apr-14, Volume: 275, Issue:15

    Topics: Amino Acid Sequence; Amino Acid Transport Systems; Arginine; Canavanine; Cysteine; Drosophila Proteins; Fungal Proteins; Guanosine Triphosphate; Humans; Membrane Transport Proteins; Molecular Sequence Data; Monomeric GTP-Binding Proteins; Neuropeptides; Protein Prenylation; Ras Homolog Enriched in Brain Protein; Saccharomyces cerevisiae; Schizosaccharomyces pombe Proteins; Structure-Activity Relationship

2000
Role of coatomer and phospholipids in GTPase-activating protein-dependent hydrolysis of GTP by ADP-ribosylation factor-1.
    The Journal of biological chemistry, 2000, Aug-04, Volume: 275, Issue:31

    Topics: ADP-Ribosylation Factor 1; Arginine; Carrier Proteins; Coatomer Protein; GTPase-Activating Proteins; Guanosine Triphosphate; Hydrolysis; Mutation; Myristic Acid; Phospholipids; Protein Processing, Post-Translational; Sequence Deletion

2000
Biochemical characterization of Rab3-GTPase-activating protein reveals a mechanism similar to that of Ras-GAP.
    The Journal of biological chemistry, 2000, Oct-13, Volume: 275, Issue:41

    Topics: Aluminum Compounds; Amino Acid Sequence; Animals; Arginine; Binding Sites; Calcium; Calmodulin; Catalysis; Fluorides; GTP-Binding Proteins; GTPase-Activating Proteins; Guanine Nucleotides; Guanosine Triphosphate; Kinetics; Molecular Sequence Data; Mutation; Protein Binding; rab3 GTP-Binding Proteins; rab3A GTP-Binding Protein; ras GTPase-Activating Proteins; Recombinant Fusion Proteins; Sequence Alignment; Substrate Specificity; Thermodynamics

2000
Arginines 29 and 59 of elongation factor G are important for GTP hydrolysis or translocation on the ribosome.
    The EMBO journal, 2000, Jul-03, Volume: 19, Issue:13

    Topics: Arginine; Biological Transport; GTP Phosphohydrolases; Guanosine Triphosphate; Hydrolysis; Peptide Elongation Factor G; Ribosomes

2000
Three-dimensional view of the surface motif associated with the P-loop structure: cis and trans cases of convergent evolution.
    Journal of molecular biology, 2000, Nov-03, Volume: 303, Issue:4

    Topics: Adenosine Triphosphate; Alanine; Amino Acid Motifs; Amino Acid Sequence; Animals; Arginine; Asparagine; Binding Sites; Conserved Sequence; Evolution, Molecular; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Models, Molecular; Molecular Sequence Data; Nucleoside-Phosphate Kinase; Protein Structure, Tertiary; Ribonucleases; Sequence Alignment; Static Electricity; Substrate Specificity

2000
Role of intrahelical arginine residues in functional properties of uncoupling protein (UCP1).
    Biochemistry, 2001, May-01, Volume: 40, Issue:17

    Topics: Animals; Arginine; Binding Sites; Biological Transport, Active; Carbon Radioisotopes; Carrier Proteins; Chloride Channels; Cricetinae; Genetic Vectors; Guanosine Triphosphate; Intracellular Fluid; Intracellular Membranes; Ion Channels; Lauric Acids; Membrane Proteins; Mitochondria; Mitochondrial Proteins; Mutagenesis, Site-Directed; Permeability; Protein Structure, Secondary; Protons; Saccharomyces cerevisiae; Uncoupling Agents; Uncoupling Protein 1

2001
The arginine finger of RasGAP helps Gln-61 align the nucleophilic water in GAP-stimulated hydrolysis of GTP.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, May-22, Volume: 98, Issue:11

    Topics: Arginine; Binding Sites; Cluster Analysis; Glutamine; Guanosine Triphosphate; Hydrolysis; p120 GTPase Activating Protein; Proto-Oncogene Proteins p21(ras); Water

2001
Dimerization of small GTPase Rab5.
    International journal of molecular medicine, 2001, Volume: 8, Issue:4

    Topics: Amino Acid Sequence; Arginine; Cell Line; Cross-Linking Reagents; Dimerization; Guanosine Triphosphate; Humans; Molecular Sequence Data; Mutation; Plasmids; Protein Binding; Proteins; rab5 GTP-Binding Proteins; Saccharomyces cerevisiae; Sequence Homology, Amino Acid; Two-Hybrid System Techniques

2001
Crystal structure of pea Toc34, a novel GTPase of the chloroplast protein translocon.
    Nature structural biology, 2002, Volume: 9, Issue:2

    Topics: Amino Acid Motifs; Amino Acid Sequence; Arginine; Binding Sites; Chloroplasts; Chromatography, Gel; Crystallography, X-Ray; Cytosol; Dimerization; GTP Phosphohydrolases; GTPase-Activating Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Magnesium; Membrane Proteins; Models, Molecular; Molecular Sequence Data; Mutation; Pisum sativum; Plant Proteins; Protein Binding; Protein Conformation; Protein Transport; Sequence Alignment

2002
RanGAP mediates GTP hydrolysis without an arginine finger.
    Nature, 2002, Feb-07, Volume: 415, Issue:6872

    Topics: Arginine; Catalytic Domain; Crystallography, X-Ray; Escherichia coli; GTPase-Activating Proteins; Guanosine Triphosphate; Humans; Hydrolysis; Models, Molecular; Nuclear Proteins; Protein Conformation; Protein Structure, Tertiary; ran GTP-Binding Protein; Recombinant Proteins; Schizosaccharomyces

2002
The direct stimulation of Gi proteins by neuropeptide Y (NPY) in the rat left ventricle.
    Biochemical pharmacology, 2002, Jun-01, Volume: 63, Issue:11

    Topics: Animals; Antibodies; Arginine; Cell Membrane; Colforsin; Cyclic AMP; Drug Interactions; GTP Phosphohydrolases; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine Triphosphate; Heart Ventricles; Hydrolysis; Kinetics; Male; Neuropeptide Y; Rats; Rats, Wistar; Ventricular Function, Left

2002
Substitution of Ser for Arg-443 in the regulatory domain of human housekeeping (GLUD1) glutamate dehydrogenase virtually abolishes basal activity and markedly alters the activation of the enzyme by ADP and L-leucine.
    The Journal of biological chemistry, 2002, Nov-29, Volume: 277, Issue:48

    Topics: Adenosine Diphosphate; Allosteric Regulation; Amino Acid Sequence; Animals; Arginine; Buffers; Catalysis; Cell Line; Cloning, Molecular; Crystallography, X-Ray; Enzyme Activation; Enzyme Inhibitors; Glutamate Dehydrogenase; Guanosine Triphosphate; Humans; Hydrogen-Ion Concentration; Kinetics; Leucine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Spodoptera

2002
Understanding the catalytic mechanism of GTPase-activating proteins: demonstration of the importance of switch domain stabilization in the stimulation of GTP hydrolysis.
    Biochemistry, 2002, Dec-31, Volume: 41, Issue:52

    Topics: Amino Acid Sequence; Amino Acid Substitution; Arginine; Binding Sites; Catalysis; cdc42 GTP-Binding Protein; Enzyme Stability; GTPase-Activating Proteins; Guanosine Triphosphate; Humans; Hydrolysis; Molecular Sequence Data; Protein Binding; Protein Structure, Tertiary; Spectrometry, Fluorescence; Tyrosine

2002
Thr-431 and Arg-433 are part of a conserved sequence motif of the glutamine amidotransferase domain of CTP synthases and are involved in GTP activation of the Lactococcus lactis enzyme.
    The Journal of biological chemistry, 2003, Mar-14, Volume: 278, Issue:11

    Topics: Adenosine Triphosphate; Allosteric Site; Amino Acid Motifs; Amino Acid Sequence; Ammonium Chloride; Anthranilate Synthase; Arginine; Carbon-Nitrogen Ligases; DNA; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Glutaminase; Guanosine Triphosphate; Kinetics; Lactococcus lactis; Methionine; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Nitrogenous Group Transferases; Protein Binding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Signal Transduction; Threonine; Valine

2003
Limited proteolysis of Escherichia coli cytidine 5'-triphosphate synthase. Identification of residues required for CTP formation and GTP-dependent activation of glutamine hydrolysis.
    European journal of biochemistry, 2003, Volume: 270, Issue:10

    Topics: Amino Acid Sequence; Arginine; Binding Sites; Carbon-Nitrogen Ligases; Catalysis; Circular Dichroism; Cytidine Triphosphate; Dimerization; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Escherichia coli; Glutaminase; Glutamine; Guanosine Triphosphate; Hydrolysis; Kinetics; Lysine; Models, Chemical; Models, Genetic; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Plasmids; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Proteins; Sequence Homology, Amino Acid; Time Factors; Trypsin

2003
Conformational changes in the phosphorylated C-terminal domain of rhodopsin during rhodopsin arrestin interactions.
    The Journal of biological chemistry, 2004, Dec-03, Volume: 279, Issue:49

    Topics: Animals; Arginine; Arrestins; Binding Sites; Cattle; Cytoplasm; Dose-Response Relationship, Drug; GTP-Binding Proteins; Guanosine Triphosphate; Lysine; Magnetic Resonance Spectroscopy; Models, Molecular; Peptides; Phosphorylation; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Rhodopsin; Serine; Signal Transduction

2004
Mutation of the highly conserved Arg165 and Glu168 residues of human Gsalpha disrupts the alphaD-alphaE loop and enhances basal GDP/GTP exchange rate.
    Journal of cellular biochemistry, 2004, Oct-01, Volume: 93, Issue:2

    Topics: Adenylyl Cyclases; Arginine; Conserved Sequence; Crystallography, X-Ray; Glutamic Acid; GTP-Binding Protein alpha Subunits, Gs; Guanosine Diphosphate; Guanosine Triphosphate; Humans; Hydrogen Bonding; Kinetics; Models, Molecular; Mutation; Protein Structure, Tertiary

2004
Estimation of EDRF and nitric oxide release using [3H]GTP-labeled human platelets.
    Thrombosis research, 1995, Jun-15, Volume: 78, Issue:6

    Topics: Animals; Arginine; Biological Assay; Blood Platelets; Bradykinin; Cattle; Cell Count; Cells, Cultured; Coculture Techniques; Cyclic GMP; Drug Interactions; Endothelium-Dependent Relaxing Factors; Endothelium, Vascular; Guanosine Triphosphate; Humans; Nitric Oxide; Nitroprusside; Superoxide Dismutase; Tritium

1995
Structural basis for the unique biological function of small GTPase RHEB.
    The Journal of biological chemistry, 2005, Apr-29, Volume: 280, Issue:17

    Topics: Amino Acid Sequence; Arginine; Asparagine; Binding Sites; Catalytic Domain; Cell Proliferation; Crystallography, X-Ray; Databases, Protein; GTP Phosphohydrolases; Guanosine Diphosphate; Guanosine Triphosphate; Humans; Hydrolysis; Magnesium; Models, Molecular; Molecular Sequence Data; Monomeric GTP-Binding Proteins; Neuropeptides; Protein Conformation; Protein Kinases; Protein Structure, Secondary; Protein Structure, Tertiary; Ras Homolog Enriched in Brain Protein; ras Proteins; Repressor Proteins; Sequence Homology, Amino Acid; TOR Serine-Threonine Kinases; Tuberous Sclerosis; Tuberous Sclerosis Complex 1 Protein; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins; X-Ray Diffraction

2005
Effects of mutagenesis in the switch I region and conserved arginines of Escherichia coli MnmE protein, a GTPase involved in tRNA modification.
    The Journal of biological chemistry, 2005, Sep-02, Volume: 280, Issue:35

    Topics: Arginine; Cell Survival; DNA Mutational Analysis; Escherichia coli; Escherichia coli Proteins; GTP Phosphohydrolases; Guanosine Triphosphate; Humans; Molecular Structure; Mutagenesis, Site-Directed; Protein Conformation; RNA, Transfer

2005
HANP1/H1T2, a novel histone H1-like protein involved in nuclear formation and sperm fertility.
    Molecular and cellular biology, 2005, Volume: 25, Issue:16

    Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Arginine; Base Sequence; Binding Sites; Cell Differentiation; Cell Nucleus; Chromatin; DNA; DNA-Binding Proteins; DNA, Complementary; Dose-Response Relationship, Drug; Epididymis; Female; Fertility; Fertilization; Genetic Vectors; Guanosine Triphosphate; Haploidy; Heterozygote; Histones; Homozygote; Male; Mice; Mice, Knockout; Microscopy, Electron; Models, Genetic; Molecular Sequence Data; Mutation; Nuclear Proteins; Phylogeny; Protamines; Protein Binding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Spermatids; Spermatozoa; Testis; Time Factors; Tissue Distribution

2005
A switch 3 point mutation in the alpha subunit of transducin yields a unique dominant-negative inhibitor.
    The Journal of biological chemistry, 2005, Oct-21, Volume: 280, Issue:42

    Topics: Aluminum Compounds; Animals; Arginine; Catalysis; Cattle; Chromatography, High Pressure Liquid; Cyclic GMP; Dose-Response Relationship, Drug; Fluorides; Genes, Dominant; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Models, Biological; Models, Molecular; Mutation; Nucleotides; Point Mutation; Protein Conformation; Recombinant Fusion Proteins; Recombinant Proteins; Retina; Rhodopsin; Signal Transduction; Spectrometry, Fluorescence; Time Factors; Transducin; Trypsin

2005
Functional analysis of backbone cyclic peptides bearing the arm domain of the HIV-1 Rev protein: characterization of the karyophilic properties and inhibition of Rev-induced gene expression.
    Biochemistry, 2005, Aug-30, Volume: 44, Issue:34

    Topics: Amino Acid Sequence; Arginine; Binding Sites; Gene Expression Regulation, Viral; Gene Products, rev; Guanosine Triphosphate; HeLa Cells; HIV-1; Humans; Peptide Library; Peptides, Cyclic; Protein Conformation; Recombinant Proteins; rev Gene Products, Human Immunodeficiency Virus

2005
Crystal structure of the GTPase domain of rat dynamin 1.
    Proceedings of the National Academy of Sciences of the United States of America, 2005, Sep-13, Volume: 102, Issue:37

    Topics: Animals; Arginine; Catalysis; Crystallization; Crystallography, X-Ray; Dynamin I; Enzyme Activation; GTP Phosphohydrolases; Guanosine Triphosphate; Kinetics; Mutation; Protein Structure, Tertiary; Rats

2005
New insights into the role of conserved, essential residues in the GTP binding/GTP hydrolytic cycle of large G proteins.
    The Journal of biological chemistry, 2006, Apr-07, Volume: 281, Issue:14

    Topics: Arginine; Escherichia coli; Glutamine; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Hydrolysis; Mutagenesis, Site-Directed; Receptors, G-Protein-Coupled; Rhodopsin; Signal Transduction; Transducin

2006
Interactions of GTP with the ATP-grasp domain of GTP-specific succinyl-CoA synthetase.
    The Journal of biological chemistry, 2006, Apr-21, Volume: 281, Issue:16

    Topics: Adenosine Triphosphate; Animals; Arginine; Binding Sites; Crystallography, X-Ray; Glutamine; Guanine; Guanosine Triphosphate; Histidine; Hydrolysis; Models, Molecular; Nitrogen; Phosphates; Phosphorylation; Promoter Regions, Genetic; Protein Binding; Protein Conformation; Protein Isoforms; Ribose; Succinate-CoA Ligases; Swine

2006
How guanylate-binding proteins achieve assembly-stimulated processive cleavage of GTP to GMP.
    Nature, 2006, Mar-02, Volume: 440, Issue:7080

    Topics: Arginine; Binding Sites; Catalysis; Crystallography, X-Ray; Dimerization; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Monophosphate; Guanosine Triphosphate; Humans; Hydrolysis; Models, Molecular; Phosphates; Protein Binding; Protein Structure, Quaternary; Protein Structure, Tertiary; Serine; Structure-Activity Relationship

2006
Mutation of a critical arginine in the GTP-binding site of transglutaminase 2 disinhibits intracellular cross-linking activity.
    The Journal of biological chemistry, 2006, May-05, Volume: 281, Issue:18

    Topics: Animals; Arginine; Binding Sites; Calcium; Cell Line, Tumor; Cross-Linking Reagents; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Models, Molecular; Mutation; Protein Glutamine gamma Glutamyltransferase 2; Protein Processing, Post-Translational; Rats; Serine; Transglutaminases; Trypsin

2006
Mechanism of allosteric regulation of transglutaminase 2 by GTP.
    Proceedings of the National Academy of Sciences of the United States of America, 2006, Dec-26, Volume: 103, Issue:52

    Topics: Allosteric Regulation; Animals; Arginine; Binding Sites; Cysteine; Disulfides; GTP-Binding Proteins; Guanosine Triphosphate; Hydrogen Bonding; Models, Molecular; Mutation; Protein Binding; Protein Glutamine gamma Glutamyltransferase 2; Protein Structure, Tertiary; Rats; Transglutaminases; Tyrosine; Water

2006
The crystal structure of the third signal-recognition particle GTPase FlhF reveals a homodimer with bound GTP.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Aug-21, Volume: 104, Issue:34

    Topics: Amino Acid Motifs; Arginine; Bacillus subtilis; Bacterial Proteins; Binding Sites; Catalysis; Crystallography, X-Ray; Dimerization; Guanosine Triphosphate; Hydrolysis; Models, Molecular; Monomeric GTP-Binding Proteins; Protein Structure, Quaternary; Protein Structure, Tertiary; Sequence Alignment; Structural Homology, Protein

2007
Role of the arginine finger in Ras.RasGAP revealed by QM/MM calculations.
    FEBS letters, 2007, Dec-11, Volume: 581, Issue:29

    Topics: Arginine; Catalysis; Computational Biology; Guanosine Triphosphate; Hydrogen Bonding; Hydrolysis; Models, Molecular; Protein Conformation; ras GTPase-Activating Proteins; ras Proteins; Static Electricity; Structure-Activity Relationship

2007
The Rap-RapGAP complex: GTP hydrolysis without catalytic glutamine and arginine residues.
    The EMBO journal, 2008, Apr-09, Volume: 27, Issue:7

    Topics: Amino Acid Sequence; Arginine; Binding Sites; Catalysis; Crystallography, X-Ray; Glutamine; GTPase-Activating Proteins; Guanosine Triphosphate; Hydrolysis; Models, Molecular; Molecular Sequence Data; Mutant Proteins; Protein Binding; Protein Structure, Secondary; rap1 GTP-Binding Proteins; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins

2008
The site for the allosteric activator GTP of Escherichia coli UMP kinase.
    FEBS letters, 2009, Jan-05, Volume: 583, Issue:1

    Topics: Alanine; Allosteric Regulation; Amino Acid Substitution; Arginine; Binding Sites; Enzyme Activation; Escherichia coli; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Histidine; Mutagenesis; Mutation; Nucleoside-Phosphate Kinase; Protein Conformation; Uridine Triphosphate

2009
Promiscuous usage of nucleotides by the DNA helicase of bacteriophage T7: determinants of nucleotide specificity.
    The Journal of biological chemistry, 2009, May-22, Volume: 284, Issue:21

    Topics: Adenosine Triphosphate; Amino Acid Substitution; Arginine; Bacteriophage T7; Crystallography, X-Ray; Cytidine Triphosphate; DNA; DNA Helicases; DNA-Directed DNA Polymerase; Guanosine Triphosphate; Hydrolysis; Kinetics; Mutant Proteins; Nucleotides; Plasmids; Protein Binding; Protein Structure, Quaternary; Protein Structure, Secondary; Substrate Specificity; Thymine Nucleotides

2009
Transition state structures and the roles of catalytic residues in GAP-facilitated GTPase of Ras as elucidated by (18)O kinetic isotope effects.
    Biochemistry, 2009, Jun-02, Volume: 48, Issue:21

    Topics: Animals; Arginine; Biocatalysis; Conserved Sequence; Electrons; GTPase-Activating Proteins; Guanosine Triphosphate; Humans; Hydrolysis; Kinetics; Mice; Models, Molecular; Mutation; Oxygen Isotopes; Protein Conformation; ras Proteins; Staining and Labeling

2009
The C1 homodimer of adenylyl cyclase binds nucleotides with high affinity but possesses exceedingly low catalytic activity.
    Neuroscience letters, 2009, Dec-18, Volume: 467, Issue:1

    Topics: Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Arginine; Enzyme Inhibitors; Fluorescence; Fluorescence Resonance Energy Transfer; Guanosine Triphosphate; Histidine; Manganese; Models, Chemical; Models, Molecular; Nucleotides; Protein Multimerization

2009
Insight into the molecular switch mechanism of human Rab5a from molecular dynamics simulations.
    Biochemical and biophysical research communications, 2009, Dec-18, Volume: 390, Issue:3

    Topics: Arginine; Catalytic Domain; Crystallography, X-Ray; Guanosine Triphosphate; Humans; Molecular Dynamics Simulation; Mutation; Proline; Protein Structure, Secondary; rab5 GTP-Binding Proteins

2009
Opposing effects of two tissue transglutaminase protein isoforms in neuroblastoma cell differentiation.
    The Journal of biological chemistry, 2010, Feb-05, Volume: 285, Issue:6

    Topics: Arginine; Binding Sites; Cell Differentiation; Cell Line, Tumor; Drug Resistance, Neoplasm; Gene Expression Regulation, Enzymologic; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Immunoblotting; Isoenzymes; Neurites; Neuroblastoma; Protein Binding; Protein Glutamine gamma Glutamyltransferase 2; Proto-Oncogene Proteins c-myc; Retinoids; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Transfection; Transglutaminases; Vasoactive Intestinal Peptide

2010
Molecular basis of a novel oncogenic mutation in GNAO1.
    Oncogene, 2011, Jun-09, Volume: 30, Issue:23

    Topics: Adenosine Triphosphatases; Amino Acid Sequence; Amino Acid Substitution; Animals; Arginine; Binding Sites; Biocatalysis; Cell Line, Tumor; Cell Transformation, Neoplastic; GTP-Binding Protein alpha Subunits, Gi-Go; GTPase-Activating Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Histidine; Humans; Mice; Models, Molecular; Mutation; NIH 3T3 Cells; Protein Structure, Secondary; Protein Structure, Tertiary; Proto-Oncogene Proteins pp60(c-src); Sequence Homology, Amino Acid; Signal Transduction; STAT3 Transcription Factor

2011
Structural analysis of the Ras-like G protein MglA and its cognate GAP MglB and implications for bacterial polarity.
    The EMBO journal, 2011, Aug-16, Volume: 30, Issue:20

    Topics: Amino Acid Sequence; Arginine; Bacterial Proteins; Catalysis; Catalytic Domain; Cell Polarity; Glutamine; Guanosine Triphosphate; Hydrolysis; Molecular Sequence Data; Myxococcus xanthus; Protein Conformation; ras Proteins

2011
The guanine cap of human guanylate-binding protein 1 is responsible for dimerization and self-activation of GTP hydrolysis.
    The FEBS journal, 2012, Volume: 279, Issue:2

    Topics: Amino Acid Motifs; Amino Acid Substitution; Arginine; Binding Sites; Databases, Protein; Dimerization; Enzyme Activation; GTP-Binding Proteins; Guanine; Guanosine Triphosphate; Humans; Hydrolysis; Kinetics; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Mutant Proteins; Protein Binding; Protein Conformation; Recombinant Proteins

2012
[The changes of metabolism in myocardium at ischemia-reperfusion and activating of the ATP-sensitive potassium channels].
    Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 2012, Volume: 58, Issue:1

    Topics: Adenosine Triphosphate; Animals; Apoptosis; Arachidonic Acid; Arginase; Arginine; Dogs; Eicosanoids; Guanosine Triphosphate; Heme; KATP Channels; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardium; Nitrate Reductase (NADH); Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Pinacidil; Reactive Nitrogen Species; Reactive Oxygen Species; Reperfusion Injury

2012
Structural basis unifying diverse GTP hydrolysis mechanisms.
    Biochemistry, 2013, Feb-12, Volume: 52, Issue:6

    Topics: Arginine; Binding Sites; Catalysis; Catalytic Domain; Glutamine; GTP Phosphohydrolases; GTPase-Activating Proteins; Guanosine Triphosphate; Humans; Hydrolysis; Models, Molecular; Protein Conformation; ras Proteins

2013
The C-terminal helix in the YjeQ zinc-finger domain catalyzes the release of RbfA during 30S ribosome subunit assembly.
    RNA (New York, N.Y.), 2015, Volume: 21, Issue:6

    Topics: Arginine; Binding Sites; Circular Dichroism; Enzyme Stability; Escherichia coli; Escherichia coli Proteins; GTP Phosphohydrolases; Guanosine Triphosphate; Lysine; Models, Molecular; Ribosomal Proteins; Ribosome Subunits, Small, Bacterial; Zinc Fingers

2015
The Structural Basis of Oncogenic Mutations G12, G13 and Q61 in Small GTPase K-Ras4B.
    Scientific reports, 2016, Feb-23, Volume: 6

    Topics: Amino Acid Sequence; Arginine; Biocatalysis; Catalytic Domain; Gene Expression; Glutamine; Glycine; Guanosine Diphosphate; Guanosine Triphosphate; Humans; Hydrolysis; Molecular Dynamics Simulation; Mutation; Neoplasm Proteins; Protein Structure, Secondary; Proto-Oncogene Proteins p21(ras)

2016
Noncanonical Myo9b-RhoGAP Accelerates RhoA GTP Hydrolysis by a Dual-Arginine-Finger Mechanism.
    Journal of molecular biology, 2016, 07-31, Volume: 428, Issue:15

    Topics: Arginine; Catalysis; Catalytic Domain; Fluorides; GTPase-Activating Proteins; Guanosine Triphosphate; Humans; Hydrolysis; Magnesium Compounds; Myosins; Protein Binding; rho GTP-Binding Proteins; rhoA GTP-Binding Protein

2016
Structural plasticity mediates distinct GAP-dependent GTP hydrolysis mechanisms in Rab33 and Rab5.
    The FEBS journal, 2017, Volume: 284, Issue:24

    Topics: Amino Acid Sequence; Animals; Arginine; Catalysis; Catalytic Domain; Glutamine; GTPase-Activating Proteins; Guanosine Triphosphate; Humans; Kinetics; Mice; Models, Chemical; Models, Molecular; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Plasmodium falciparum; Protein Conformation; Protein Stability; Protozoan Proteins; rab GTP-Binding Proteins; rab1 GTP-Binding Proteins; rab5 GTP-Binding Proteins; Recombinant Fusion Proteins; Saccharomyces cerevisiae Proteins; Sequence Alignment; Structure-Activity Relationship

2017
Atypical Switch-I Arginine plays a catalytic role in GTP hydrolysis by Rab21 from Entamoeba histolytica.
    Biochemical and biophysical research communications, 2018, 11-30, Volume: 506, Issue:3

    Topics: Amino Acid Motifs; Amino Acid Sequence; Arginine; Bacterial Proteins; Binding Sites; Biocatalysis; Entamoeba histolytica; Glutamine; Guanosine Triphosphate; Hydrolysis; Kinetics; Models, Molecular; Mutant Proteins; Protein Binding; rab GTP-Binding Proteins; Structure-Activity Relationship

2018
Arg-78 of Nprl2 catalyzes GATOR1-stimulated GTP hydrolysis by the Rag GTPases.
    The Journal of biological chemistry, 2019, 02-22, Volume: 294, Issue:8

    Topics: Amino Acid Substitution; Arginine; GTPase-Activating Proteins; Guanosine Triphosphate; Humans; Hydrolysis; Monomeric GTP-Binding Proteins; Mutation, Missense; Repressor Proteins; Tumor Suppressor Proteins

2019
Millisecond molecular dynamics simulations of KRas-dimer formation and interfaces.
    Biophysical journal, 2022, 10-04, Volume: 121, Issue:19

    Topics: Arginine; Extracellular Signal-Regulated MAP Kinases; GTPase-Activating Proteins; Guanosine Triphosphate; Lipid Bilayers; Molecular Dynamics Simulation; Phosphates; raf Kinases; Serine

2022
Crystal Structures of Flavivirus NS5 Guanylyltransferase Reveal a GMP-Arginine Adduct.
    Journal of virology, 2022, 07-27, Volume: 96, Issue:14

    Topics: Arginine; Encephalitis Viruses, Tick-Borne; Flavivirus; Guanosine Triphosphate; Methyltransferases; Models, Molecular; Nucleotidyltransferases; RNA Caps; RNA, Viral; Viral Nonstructural Proteins

2022
GAP positions catalytic H-Ras residue Q61 for GTP hydrolysis in molecular dynamics simulations, complicating chemical rescue of Ras deactivation.
    Computational biology and chemistry, 2023, Volume: 104

    Topics: Arginine; Catalysis; GTPase-Activating Proteins; Guanosine Triphosphate; Hydrolysis; Molecular Dynamics Simulation

2023
Dietary supplementation with L-citrulline improves placental angiogenesis and embryonic survival in gilts.
    Experimental biology and medicine (Maywood, N.J.), 2023, Volume: 248, Issue:8

    Topics: Animals; Arginine; Citrulline; Dietary Supplements; Female; Guanosine Triphosphate; Placenta; Polyamines; Pregnancy; Swine

2023
Collateral sensitivity to gemcitabine (2',2'-difluorodeoxycytidine) and cytosine arabinoside of daunorubicin- and VM-26-resistant variants of human small cell lung cancer cell lines.
    Biochemical pharmacology, 2001, Jun-01, Volume: 61, Issue:11

    Topics: Adenosine Triphosphate; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Carcinoma, Small Cell; Cell Survival; Cytarabine; Cytidine Deaminase; Daunorubicin; Deoxycytidine; Deoxycytidine Kinase; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Gemcitabine; Guanosine Triphosphate; Humans; Lung Neoplasms; Nucleoside Deaminases; Teniposide; Thymidine Kinase; Tumor Cells, Cultured; Uridine Triphosphate

2001