arginine and guanidine

arginine has been researched along with guanidine in 213 studies

Research

Studies (213)

TimeframeStudies, this research(%)All Research%
pre-199037 (17.37)18.7374
1990's32 (15.02)18.2507
2000's72 (33.80)29.6817
2010's63 (29.58)24.3611
2020's9 (4.23)2.80

Authors

AuthorsStudies
Nezu, J; Oku, A; Sai, Y; Sakamoto, K; Shimane, M; Tamai, I; Tsuji, A; Yabuuchi, H1
Nezu, JI; Ohashi, R; Oku, A; Sai, Y; Shimane, M; Tamai, I; Tsuji, A; Yabuuchi, H1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Hedstrom, L; Phillips, MA; Rutter, WJ1
Frankel, AD; Tan, R1
Fermi, G; Perutz, MF; Shih, DT; Stein, P; Williamson, D1
Post, RL; Suzuki, K1
Ellouali, M; Jozefonvicz, J; Khamlichi, S; Muller, D1
Campion, SR; Cook, JS; Engler, DA; Hauser, MR; Niyogi, SK1
Fuks, R; Jozefonvicz, J; Khamlichi, S; Muller, D1
Fairlamb, AH; Hunter, KJ1
Hibbs, JB; Taintor, RR; Vavrin, Z1
Marie, JC; Robichon, A1
Ludden, PW; Pope, MR; Saari, LL1
Aoyagi, K; Nagase, S; Narita, M; Sakamoto, M; Tojo, S1
Brewer, JM; Qaw, FS1
Becaus, I; De Deyn, P; Lornoy, W; Lowenthal, A; Marescau, B1
Church, FC; Griffith, MJ; Villanueva, GB1
Byus, CV; Fletcher, WH1
Traub, P; Vorgias, CE1
Miwa, N; Sawada, T; Suzuki, A1
Goodman, DS; Kawakami, M1
Attwell, NA; Clement, DJ; Clipson, NJ; Fincham, DA; Hooley, P; Stanley, MS1
Christensen, T; Dupont, C; Frandsen, TP; Honzatko, RB; Lehmbeck, J; Stoffer, B; Svensson, B1
De Deyn, PP; Marescau, B; Qureshi, IA; Robitaille, P; Vanasse, M1
Mironov, SL1
Ahmad, F; Taneja, S1
Braiman, MS; Briercheck, DM; Walter, TJ1
McDonald, IK; Mitchell, JB; Nandi, CL; Price, SL; Thornton, JM1
Ahn, J; Hondal, RJ; Kraynov, VS; Tsai, MD; Werneburg, BG; Zhong, X1
Farmer, BT; Venters, RA1
Frankel, AD; Harada, K1
Ahn, JH; Lee, YP; Rhee, JS1
Sethumadhavan, K; Ullah, AH1
Al Banchaabouchi, M; D'Hooge, R; De Deyn, PP; Levillain, O; Marescau, B; Van Daele, A; Van Marck, E1
Ash, DE; Dismukes, GC; Khangulov, SV; Sossong, TM1
Alemán, C; Barril, X; Luque, FJ; Orozco, M1
Balsam, L; Nikbakht, N1
Consonni, R; Longhi, R; Santomo, L; Tenni, R; Zetta, L1
Juji, T; Kondo, H; Kumagai, I; Shinoki, K; Tsumoto, K; Uchikawa, M1
Southan, GJ; Srinivasan, A1
Abbruzzese, A; Beninati, S; Caraglia, M; Colonna, G; Hershey, JW; Ragone, R; Stiuso, P1
Buchinska, TV1
Babu, BR; Frey, C; Griffith, OW1
Goodin, DB; Hirst, J1
Bespalova, ZhD; Bushuev, VN; Rubina, AIu1
Ohmiya, Y; Viviani, VR1
Büllesbach, EE; Schwabe, C1
Hu, W; Liu, A; Majumdar, A; Patel, DJ; Rosen, MK1
Allocati, N; Casalone, E; Di Ilio, C; Masulli, M; Parker, MW; Polekhina, G; Rossjohn, J1
Chuang, DT; Chuang, JL; Mandel, H; Sansaricq, C; Wynn, RM1
Stauffer, CE; Sullivan, JF1
Arendt, M; Grawe, T; Rensing, S; Schrader, T; Springer, A1
Chen, X; Galligan, JJ; Kreulen, DL; Li, X; Tang, X; Wang, PG; Xian, M; Zheng, Z1
Ferry, JG; Tripp, BC; Tu, C1
Babovic-Vuksanovic, D; Burghardt, TP; Carpenter, JF; Gregersen, N; Kim, YS; Nguyen, TV; Riggs, C; Vockley, J1
Berndt, KD; Chiaraluce, R; Consalvi, V; Ladenstein, R; Lebbink, JH1
Akhtar, MS; Bhakuni, V1
Ramakrishna, T; Raman, B; Rao, ChM; Rao, KS; Srinivas, V1
Leitner, A; Lindner, W1
HATT, JL; THI, AN; VAN THOAI, N1
GRIFFITHS, DE; WHITE, IG1
LORAND, L; RULE, NG1
MENAGE, A; MOREL, G2
AUDIT, C; ROBIN, Y1
ROBIN, Y; ROCHE, J1
AUDIT, C; ROBIN, Y; ZAPPACOSTA, S1
ROBIN, Y; ROCHE, J; THOAI, N; ZAPPACOSTA, S1
ALLARD, C; CHAMBRE, MM; STARON, T1
KOCH, A; LWOFF, A; LWOFF, M1
ROBIN, Y; THOAI, NV; ZAPPACOSTA, S1
AGRAWAL, HC; PANT, R1
LWOFF, A; LWOFF, M1
LACOMBE, G; ROCHE, J1
BOULANGER, P; CHARLIER, H; OSTEUX, R; SACQUET, E1
HORNER, WH1
OLOMUCKI, A1
CASTLEMAN, H; ERLANGER, BF1
VIRDEN, R; WATTS, DC1
BARET, R; BROC, A; MOURGUE, M1
HILL, DL; JUDD, J; VANEYS, J1
CONCONI, F; GRAZI, E; VIGI, V1
LIKAR, M; SCHAUER, P1
Andreotti, G; Motta, A1
Guo, T; Lu, J; Xie, Q; Zhou, HM1
Arakawa, T; Ejima, D; Kumagai, I; Tsumoto, K; Umetsu, M1
Arison, BH; Blair, IA; Lee, SH; Oe, T; Silva Elipe, MV1
Jaiswal, S; Khanna, N; Swaminathan, S1
Dewanti, AR; Mitra, B; Xu, Y1
Ikeura, Y; Iwamoto, M; Kamo, N; Shimono, K; Sudo, Y1
Amarnath, V; Bernoud-Hubac, N; Boutaud, O; Oates, JA; Roberts, LJ; Zagol-Ikapitte, I1
Armbrüster, M; Gschwind, RM; Zubrzycki, IZ1
Csonka, IP; Paizs, B; Suhai, S1
Buchberger, W; Ferdig, M1
Ferry, JG; Gorrell, A; Lawrence, SH1
Geiger, L; Schmuck, C1
Isacoff, EY; Pathak, MM; Tombola, F1
Lindner, W; Schug, KA1
Gellman, SH; Menon, AK; Potocky, TB1
Baynes, BM; Trout, BL; Wang, DI1
Arakawa, T; Ejima, D; Ishibashi, M; Kita, Y; Tokunaga, M; Tsumoto, K1
Blakely, EL; Fisher, N; Jackson, MJ; Meunier, B; Mitchell, AL; Nijtmans, LG; Schaefer, AM; Taylor, RW; Turnbull, DM1
Chung, HY; Kim, YJ; Yokozawa, T1
Hagiwara, T; Hidaka, Y; Yamada, M1
Dunaway-Mariano, D; Galkin, A; Herzberg, O; Lu, X1
Arakawa, T; Ejima, D; Tsumoto, K; Yumioka, R1
Ide, N; Kitabatake, N; Masuda, T1
Guillén Schlippe, YV; Hedstrom, L1
Davidson, AR; Kay, LE; Mittermaier, A; Zarrine-Afsar, A1
Arakawa, T; Ejima, D; Ishibashi, M; Tokunaga, M; Tsumoto, K1
Imamoto, Y; Kamikubo, H; Kataoka, M; Shimizu, N; Yamazaki, Y1
Guo, Y; Hopkinson, AC; Li, X; Orlova, G; Rodriquez, CF; Siu, CK; Siu, KW1
Goun, EA; Jones, LR; Pillow, TH; Rothbard, JB; Wender, PA1
Christianson, DW; Di Costanzo, L; Flores, LV1
Hou, JB; Jin, L; Liu, Y; Xu, PX; Zhao, YF1
Arakawa, T; Ejima, D; Fukada, H; Kita, Y; Tsumoto, K1
Ando, E; Hamazaki, A; Ishida, M; Kuyama, H; Nakazawa, T; Nishida, K; Nishimura, O; Norioka, S; Oka, M; Okamura, TA; Tsunasawa, S; Ueyama, N; Yamaguchi, M1
Arakawa, T; Ejima, D; Kita, Y; Obeyama, N; Tanaka, Y; Timasheff, SN; Tsumoto, K1
Suzuki, T; Uda, K1
Ahn, YH; Cho, K; Ji, ES; Lee, JY; Yoo, JS1
Hong, M; Tang, M; Waring, AJ1
Ealick, SE; Kurinov, I; Pradeep, L; Scheraga, HA1
Hof, F; Koivisto, BD; McKie, AH; Sarycheva, OV; Wang, X1
Carver, JA; Ecroyd, H1
Bimbong, RN; Bouchoux, G; Bourcier, S; Desaphy, S; Malosse, C1
Hong, M; Lehrer, RI; Tang, M; Waring, AJ1
D'Aléo, A; Giraud, N; Kahn, R; Maury, O; Pompidor, G; Toupet, L; Vicat, J1
Canfield, JM; Groover, OA; Sun, L; Warncke, K1
Kuznetsova, IM; Shavlovsky, MM; Stepanenko, OV; Turoverov, KK; Uversky, VN; Verkhusha, VV1
Chen, X; Hayakawa, S; Hvelplund, P; Matsubara, H; Nielsen, SB; Panja, S; Turecek, F1
Castreno, P; Congreve, A; de Mendoza, J; Kielar, F; Law, GL; New, EJ; Parker, D; Wong, KL1
Hof, F; McIndoe, JS; McQuinn, K1
Arakawa, T; Hirano, A; Shiraki, K1
Durani, S; Pednekar, D; Tendulkar, A1
Bonnet, V; Boucher, JL; Dhimane, H; Kizirian, JC; Le Corre, L; Levraud, C1
GEMMILL, CL1
Carvajal, N; García, D; Lobos, M; Orellana, MS; Uribe, E1
Beck-Sickinger, AG; Bernhardt, G; Buschauer, A; Hutzler, C; Keller, M; Pop, N1
Schneider, CP; Trout, BL1
Chen, J; Ding, H; Li, X; Liu, Y; Ma, G; Su, Z; Wang, Y1
Alemán, C; Calaza, MI; Cativiela, C; Flores-Ortega, A; Jiménez, AI; Nussinov, R; Ruoslahti, E; Zanuy, D1
Bouchet, A; Disalvo, EA; Lairion, F1
Balland, V; Boucher, JL; Giroud, C; Mattioli, TA; Moreau, M; Santolini, J; Stuehr, DJ; Xu-Li, Y1
Amyes, TL; Barnett, SA; Gerlt, JA; Richard, JP; Wood, BM1
Fujishima, T; Harayama, H; Tanaka, C; Tsuji, G1
Lange, C; Lilie, H; Rudolph, R; Tischer, A1
Bernsel, A; Freites, JA; Myint, PC; Schow, EV; Tobias, DJ; von Heijne, G; White, SH1
Ghosh, A; Hochstrasser, RM; Tucker, MJ1
de Boer, L; Nguyen, LT; Vogel, HJ; Zaat, SA1
Bernhardt, G; Brennauer, A; Buschauer, A; Keller, M; Pluym, N; Pop, N; Ziemek, R1
Bernhardt, G; Buschauer, A; Keller, M1
Behlke, J; Cardoso, MC; Herce, HD; Hoffmann, D; Lättig-Tünnemann, G; Morano, I; Palm-Apergi, C; Prinz, M1
Flemer, S; Madalengoitia, JS1
García-Moreno, B; Harms, MJ; Schlessman, JL; Sue, GR1
Li, X; Liang, W; Moss, CL; Tureček, F1
Balakrishnan, S; Scheuermann, MJ; Zondlo, NJ1
Anantharamaiah, GM; Deivanayagam, CCS; Garber, DW; Handattu, SP; McPherson, DT; Mishra, VK; Nayyar, G; Palgunachari, MN; Segrest, JP; Shin, R1
Abagyan, R; Neves, MA; Yeager, M1
Beck-Sickinger, AG; Findeisen, M; Meier, R; Meiler, J; Olsson, R; Rathmann, D; Würker, C1
Castanho, MA; Franquelim, HG; Gaspar, D; Schneider, JP; Sinthuvanich, C; Veiga, AS1
Ausili, A; D'Auria, S; Dattelbaum, JD; Fessas, D; Pennacchio, A; Schiraldi, A; Staiano, M1
Huang, C; Pu, W; Wu, L; Xu, D; Zhao, H1
Mamba, BB; Mbukwa, EA; Msagati, TA1
Arakawa, T; Hirano, A; Kameda, T; Shinozaki, D; Shiraki, K1
Loganathan, D; Srivastava, A1
Bernhardt, G; Buschauer, A; Holzammer, T; Kaske, M; Keller, M1
Caceres, TB; Chen, J; Chen, X; Gong, Q; Hevel, JM; Liu, L; Peng, J; Shi, Y; Teng, M; Wang, C; Wang, J; Wu, J; Zhang, Z; Zhu, Y; Zuo, X1
Cheng, RP; Hsu, HC; Kuo, HT; Kuo, LH; Ting, YT; Wang, WR; Weng, MH; Wu, CH; Yang, PA1
Guo, C; Guo, M; Pan, Y1
Chen, T; Huang, Y; Liang, D; Su, C; Sun, J; Wang, N; Xia, Y; Zhu, L1
Battocchio, C; Cipolla, L; Nicotra, F; Polzonetti, G; Russo, L; Taraballi, F1
Auton, M; Lange, C; Lilie, H; Tischer, A1
Ghosh, S; Maiti, KK; Mohapatra, S; Nair, JB1
Coppens, MO; Garde, S; Wu, E1
Abbott, NL; Acevedo-Vélez, C; Gellman, SH; Ma, CD; Wang, C1
Shah, D; Shaikh, AR1
Falconer, RJ; Platts, L1
Chen, X; Liu, D; Liu, L; Song, W; Sun, X1
Ensenauer, R; Häussinger, D; Mayatepek, E; Schlune, A; Vom Dahl, S1
Cai, T; Chen, K; Li, S; Liu, Y; Shi, J; Wang, J; Xu, Z; Yang, Y; Yang, Z; Zhang, Z; Zhu, W1
Alamgir, M; Jahangir, TM; Khuhawar, MY; Zounr, RA1
Anderson, JL; Armstrong, CT; Dempsey, CE; Mason, PE1
Hamada, Y1
Arakawa, T; Shiraki, K; Yoshizawa, S1
Dauter, M; Dauter, Z; Malinska, M1
Hada, S; Jeong, SH; Kim, NA; Thapa, R1
Jiang, J; Sun, K; Wang, A; Wei, S; Zhou, J; Zhou, L; Zhou, R1
Chen, Q; Ma, M; Yan, Z; Zhang, N; Zhao, X1
Yaylayan, VA; Zhu, Y1
Cramer, SM; Garde, S; Parimal, S1
Ahmed, M; Jacobs, MI; Kostko, O; Xu, B1
Hansen, DF; Mackenzie, HW1
Avilés-Moreno, JR; Berden, G; Martínez-Haya, B; Oomens, J3
Lan, H; Lyu, M; Wen, L; Xiao, H; Yin, Z; Zuo, Z1
Banerjee, UC; Bihade, UR; Patil, MD; Rathod, VP1
Alim, K; Boutin, JA; Chartrel, N; Chuquet, J; Dubessy, C; Lefranc, B; Leprince, J; Picot, M; Sopkova-de Oliveira Santos, J; Vaudry, D; Vaudry, H1
Bootsma, AN; Wheeler, SE1
Ifuku, S; Izawa, H; Kinai, M; Morimoto, M; Saimoto, H1
Balskus, EP; Boal, AK; Mitchell, AJ; Ng, TL; Rohac, R1
Arakawa, T; Hirano, A; Iwashita, K; Kameda, T; Sakuraba, S; Shiraki, K; Ura, T1
Ding, J; Du, L; Li, S; Pan, X; Shao, F; Wang, DC; Xue, J; Yao, H; Yao, Q1
Ding, G; Kang, Z; Meng, Q; Meng, Z1
Altelaar, M; Ferrari, L; Förster, FG; Geerts, WJC; Hoogenraad, CC; Konstantoulea, K; Kos, R; Rüdiger, SGD; Stucchi, R; van Bezouwen, LS; van de Kamp, G1
Gehrig, PM; Grossmann, J; Hottiger, MO; Leutert, M; Nowak, K; Panse, C; Schlapbach, R1
Arakawa, T; Shiraki, K; Ura, T1
Kalinina, AD; Ke, M; Krylov, BV; Penniyaynen, VA; Plakhova, VB; Podzorova, SA; Rogachevskii, IV; Samosvat, DM; Zegrya, GG1
Clemente, C; Colombano, A; Dall'Angelo, S; Fewer, DP; Houssen, WE; Johnson, N; Jokela, J; Nardone, B; Ouyang, X; Popin, RV; Wahlsten, M1
Bakarić, D; Jurašin, DD; Pašalić, L; Pem, B; Vazdar, M1
Fukui, M; Kinuya, S; Mishiro, K; Ogawa, K; Ueno, T; Wakabayashi, H1
Ghosh, S; Jana, NR; Panja, P; Ray, R1

Reviews

8 review(s) available for arginine and guanidine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Noncovalent binding between guanidinium and anionic groups: focus on biological- and synthetic-based arginine/guanidinium interactions with phosph[on]ate and sulf[on]ate residues.
    Chemical reviews, 2005, Volume: 105, Issue:1

    Topics: Anions; Arginine; Binding Sites; Guanidine; Models, Biological; Models, Molecular; Molecular Structure; Organophosphonates; Phosphates; Sulfates

2005
Is arginine a protein-denaturant?
    Protein expression and purification, 2005, Volume: 42, Issue:1

    Topics: Amino Acids, Aromatic; Arginine; Guanidine; Protein Denaturation; Protein Structure, Tertiary; Surface Properties; Tryptophan; Tyrosine

2005
Molecular transporters: synthesis of oligoguanidinium transporters and their application to drug delivery and real-time imaging.
    Chembiochem : a European journal of chemical biology, 2006, Volume: 7, Issue:10

    Topics: Amino Acid Sequence; Animals; Arginine; Biological Transport; Carbamates; Carrier Proteins; Drug Carriers; Drug Delivery Systems; Firefly Luciferin; Gene Products, tat; Guanidine; Humans; Hydrogen Bonding; Luminescent Agents; Membrane Potentials; Molecular Sequence Data; Molecular Structure; Peptide Fragments; Polymers; Structure-Activity Relationship

2006
Suppression of protein interactions by arginine: a proposed mechanism of the arginine effects.
    Biophysical chemistry, 2007, Volume: 127, Issue:1-2

    Topics: Arginine; Guanidine; Proteins; Solubility; Surface Tension; Water

2007
Arginine in membranes: the connection between molecular dynamics simulations and translocon-mediated insertion experiments.
    The Journal of membrane biology, 2011, Volume: 239, Issue:1-2

    Topics: Arginine; Guanidine; Ion Transport; Lipid Bilayers; Membrane Proteins; Membranes; Molecular Dynamics Simulation; Peptides; Thermodynamics; Water

2011
Hyperargininemia due to arginase I deficiency: the original patients and their natural history, and a review of the literature.
    Amino acids, 2015, Volume: 47, Issue:9

    Topics: Arginase; Arginine; Child, Preschool; Female; Guanidine; Humans; Hyperammonemia; Hyperargininemia; Infant; Liver Diseases; Paraplegia; Seizures

2015
The rational design of cell-penetrating peptides for application in delivery systems.
    Peptides, 2019, Volume: 121

    Topics: Amino Acid Sequence; Animals; Arginine; Biological Transport; Cell-Penetrating Peptides; Drug Delivery Systems; Guanidine; Humans; Hydrophobic and Hydrophilic Interactions; Peptides, Cyclic; Protein Conformation; Protein Engineering; Structure-Activity Relationship

2019

Trials

1 trial(s) available for arginine and guanidine

ArticleYear
Serum guanidino compound levels in uremic pediatric patients treated with hemodialysis or continuous cycle peritoneal dialysis. Correlations between nerve conduction velocities and altered guanidino compound concentrations.
    Nephron, 1995, Volume: 69, Issue:4

    Topics: Adolescent; Adult; Arginine; Child; Child, Preschool; Creatinine; Female; Guanidine; Guanidines; Humans; Male; Methylguanidine; Neural Conduction; Peritoneal Dialysis; Renal Dialysis; Succinates; Urea; Uremia

1995

Other Studies

204 other study(ies) available for arginine and guanidine

ArticleYear
Novel membrane transporter OCTN1 mediates multispecific, bidirectional, and pH-dependent transport of organic cations.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 289, Issue:2

    Topics: Animals; Biological Transport, Active; Carrier Proteins; Cell Line; Gene Expression; Humans; Hydrogen-Ion Concentration; Membrane Potentials; Membrane Proteins; Membrane Transport Proteins; Oocytes; Organic Cation Transport Proteins; Quinidine; RNA, Messenger; Symporters; Tetraethylammonium Compounds; Xenopus laevis

1999
Na(+)-dependent carnitine transport by organic cation transporter (OCTN2): its pharmacological and toxicological relevance.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:2

    Topics: Biological Transport, Active; Carnitine; Carrier Proteins; Cations; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Humans; Hydrogen-Ion Concentration; Kidney; Membrane Proteins; Organic Cation Transport Proteins; Sodium; Solute Carrier Family 22 Member 5; Stereoisomerism

1999
Guanidine derivatives restore activity to carboxypeptidase lacking arginine-127.
    Protein science : a publication of the Protein Society, 1992, Volume: 1, Issue:4

    Topics: Animals; Arginine; Carboxypeptidases; Carboxypeptidases A; Dipeptides; Guanidine; Guanidines; Methylguanidine; Mutation; Peptides; Rats; Substrate Specificity

1992
Circular dichroism studies suggest that TAR RNA changes conformation upon specific binding of arginine or guanidine.
    Biochemistry, 1992, Oct-27, Volume: 31, Issue:42

    Topics: Amino Acid Sequence; Arginine; Bacteriophage T7; Base Sequence; Binding Sites; Circular Dichroism; DNA-Directed RNA Polymerases; Gene Products, tat; Guanidine; Guanidines; HIV; Kinetics; Molecular Sequence Data; Nucleic Acid Conformation; Peptides; RNA; tat Gene Products, Human Immunodeficiency Virus; Transcription, Genetic

1992
Structure-function relationships in the low-affinity mutant haemoglobin Aalborg (Gly74 (E18)beta----Arg).
    Journal of molecular biology, 1992, Aug-05, Volume: 226, Issue:3

    Topics: Amino Acid Sequence; Arginine; Glycine; Guanidine; Guanidines; Hemoglobins, Abnormal; Humans; Macromolecular Substances; Models, Molecular; Protein Conformation; Structure-Activity Relationship

1992
A Hofmeister effect on the phosphoenzyme of Na,K-ATPase.
    Society of General Physiologists series, 1991, Volume: 46

    Topics: Acetates; Animals; Anions; Arginine; Aspartic Acid; Bromides; Cations; Chlorides; Choline; Dogs; Guanidine; Guanidines; Kidney; Lysine; Nephelometry and Turbidimetry; Nitrates; Sodium; Sodium-Potassium-Exchanging ATPase; Succinates

1991
Affinity of trypsin for amidine derivatives immobilized on dextran-coated silica supports.
    Journal of chromatography, 1991, Jul-12, Volume: 548, Issue:1-2

    Topics: Adsorption; Amidines; Animals; Arginine; Cattle; Chromatography, Ion Exchange; Dextrans; Guanidine; Guanidines; Hydrogen-Ion Concentration; Indicators and Reagents; Silicon Dioxide; Thermodynamics; Trypsin

1991
Critical functional requirement for the guanidinium group of the arginine 41 side chain of human epidermal growth factor as revealed by mutagenic inactivation and chemical reactivation.
    The Journal of biological chemistry, 1992, Feb-05, Volume: 267, Issue:4

    Topics: Amino Acids; Animals; Arginine; Binding, Competitive; Epidermal Growth Factor; ErbB Receptors; Guanidine; Guanidines; Humans; Keratinocytes; Mice; Mice, Inbred BALB C; Mutagenesis, Site-Directed

1992
Specific adsorption of serine proteases on coated silica beads substituted with amidine derivatives.
    Journal of chromatography, 1990, Jun-27, Volume: 510

    Topics: Adsorption; Amidines; Animals; Arginine; Benzamidines; Cattle; Chromatography, Affinity; Fibrinolysin; Guanidine; Guanidines; Humans; Indicators and Reagents; Serine Endopeptidases; Silicon Dioxide; Thermodynamics; Thrombin

1990
Separation and quantitation of the polyamine biosynthesis inhibitor D,L-alpha-difluoromethylarginine and other guanidine-containing compounds by high-performance liquid chromatography.
    Analytical biochemistry, 1990, Nov-01, Volume: 190, Issue:2

    Topics: Animals; Arginine; Carboxy-Lyases; Chromatography, High Pressure Liquid; Crithidia; Fluorescent Dyes; Guanidine; Guanidines; Sensitivity and Specificity

1990
L-arginine is required for expression of the activated macrophage effector mechanism causing selective metabolic inhibition in target cells.
    Journal of immunology (Baltimore, Md. : 1950), 1987, Jan-15, Volume: 138, Issue:2

    Topics: Aconitate Hydratase; Adenosine Diphosphate Ribose; Amino Acids; Animals; Arginase; Arginine; Cell Survival; Cells, Cultured; Culture Media; DNA; Guanidine; Guanidines; Homoarginine; Lipopolysaccharides; Macrophage Activation; Macrophages; Metabolism; Mice; Mitochondria; omega-N-Methylarginine; Oxidation-Reduction; Polyamines; Stereoisomerism; Structure-Activity Relationship

1987
Chemical modification of guanidinium groups of vasoactive intestinal peptide.
    Biochimica et biophysica acta, 1987, Feb-20, Volume: 923, Issue:2

    Topics: Aldehydes; Amino Acids; Animals; Arginine; Azides; Binding, Competitive; Cross-Linking Reagents; Cyclic AMP; Guanidine; Guanidines; In Vitro Techniques; Phenylglyoxal; Photochemistry; Rats; Receptors, Gastrointestinal Hormone; Receptors, Vasoactive Intestinal Peptide; Vasoactive Intestinal Peptide

1987
N-glycohydrolysis of adenosine diphosphoribosyl arginine linkages by dinitrogenase reductase activating glycohydrolase (activating enzyme) from Rhodospirillum rubrum.
    The Journal of biological chemistry, 1986, Aug-05, Volume: 261, Issue:22

    Topics: Adenosine Diphosphate Ribose; Arginine; Chromatography, High Pressure Liquid; Glycoside Hydrolases; Guanidine; Guanidines; Hydrolysis; Kinetics; Magnetic Resonance Spectroscopy; Mass Spectrometry; N-Glycosyl Hydrolases; Nucleoside Diphosphate Sugars; Rhodospirillum rubrum

1986
[Effect of active oxygen on guanidine synthesis from various guanidino compounds in vitro].
    Nihon Jinzo Gakkai shi, 1987, Volume: 29, Issue:11

    Topics: Animals; Arginine; Glycine; Guanidine; Guanidines; In Vitro Techniques; Liver; Oxygen; Rats

1987
Arginyl residues and thermal stability in proteins.
    Molecular and cellular biochemistry, 1986, Volume: 71, Issue:2

    Topics: Alcohol Dehydrogenase; Amides; Arginine; Chemical Phenomena; Chemistry; Drug Stability; Guanidine; Guanidines; Hot Temperature; Imidoesters; Methylurea Compounds; Phosphopyruvate Hydratase; Saccharomyces cerevisiae; Serum Albumin, Bovine

1986
Guanidino compounds in uraemic dialysed patients.
    Clinica chimica acta; international journal of clinical chemistry, 1986, Jun-15, Volume: 157, Issue:2

    Topics: Adult; Aged; Arginine; Creatine; Creatinine; Female; Guanidine; Guanidines; Humans; Male; Methylguanidine; Middle Aged; Renal Dialysis; Succinates; Uremia

1986
Structure-function relationships in heparin cofactor II: chemical modification of arginine and tryptophan and demonstration of a two-domain structure.
    Archives of biochemistry and biophysics, 1986, Volume: 246, Issue:1

    Topics: Amino Acids; Antithrombin III; Arginine; Binding Sites; Bromosuccinimide; Chromatography; Circular Dichroism; Diacetyl; Glycoproteins; Guanidine; Guanidines; Heparin Cofactor II; Kinetics; Protein Denaturation; Structure-Activity Relationship; Tryptophan

1986
Direct cytochemical localization of catalytic subunits dissociated from cAMP-dependent protein kinase in Reuber H-35 hepatoma cells. I. Development and validation of fluorescinated inhibitor.
    The Journal of cell biology, 1982, Volume: 93, Issue:3

    Topics: Animals; Arginine; Carrier Proteins; Catalysis; Cell Nucleolus; Cells, Cultured; Cyclic AMP; Cyclohexanones; Cytoplasm; Fluorescein-5-isothiocyanate; Fluoresceins; Guanidine; Guanidines; Histocytochemistry; Intracellular Signaling Peptides and Proteins; Liver Neoplasms, Experimental; Peptides; Protein Kinases; Thiocyanates

1982
Involvement of the N-terminal polypeptide of vimentin in the formation of intermediate filaments.
    Journal of cell science, 1983, Volume: 63

    Topics: Animals; Arginine; Calpain; Cells, Cultured; Chromatography, Affinity; Cytoskeleton; DNA, Single-Stranded; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Guanidine; Guanidines; Intermediate Filament Proteins; Kinetics; Lysine; Microscopy, Electron; Peptide Fragments; Peptides; Vimentin

1983
Conformational changes in human urokinase induced by a specific reduction of disulfide bond in Cys-194-Cys-222 associated with exhibition of enzymatic activity.
    Biochimica et biophysica acta, 1984, Nov-23, Volume: 791, Issue:1

    Topics: Arginine; Circular Dichroism; Disulfides; Guanidine; Guanidines; Humans; Kinetics; Protein Conformation; Protein Denaturation; Spectrophotometry, Infrared; Structure-Activity Relationship; Tyrosine; Urokinase-Type Plasminogen Activator

1984
Effects of protein modification procedures on the interaction between 25-hydroxyvitamin D and the human plasma binding protein for vitamin D and its metabolites.
    Biochemistry, 1981, Sep-29, Volume: 20, Issue:20

    Topics: 25-Hydroxyvitamin D 2; Arginine; Carrier Proteins; Ergocalciferols; Guanidine; Guanidines; Humans; Lysine; Methylation; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Vitamin D; Vitamin D-Binding Protein

1981
Salt sensitivity and arginine toxicity in Aspergillus nidulans.
    Biochemical Society transactions, 1995, Volume: 23, Issue:1

    Topics: Arginine; Aspergillus nidulans; Guanidine; Guanidines; Homoarginine; Kinetics; Lysine; Ornithine; Osmolar Concentration; Salts; Stereoisomerism

1995
Mutational analysis of the roles in catalysis and substrate recognition of arginines 54 and 305, aspartic acid 309, and tryptophan 317 located at subsites 1 and 2 in glucoamylase from Aspergillus niger.
    Biochemistry, 1995, Aug-15, Volume: 34, Issue:32

    Topics: Arginine; Aspartic Acid; Aspergillus niger; Base Sequence; Catalysis; DNA Mutational Analysis; DNA Primers; Enzyme Stability; Glucan 1,4-alpha-Glucosidase; Guanidine; Guanidines; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Substrate Specificity; Thermodynamics; Tryptophan

1995
Monovalent amidiniums block calcium channels in chick sensory neurons.
    The Journal of membrane biology, 1994, Volume: 141, Issue:3

    Topics: Amidines; Animals; Arginine; Barium; Calcium Channel Blockers; Calcium Channels; Chickens; Ganglia, Spinal; Glucose; Guanidine; Guanidines; In Vitro Techniques; Kinetics; Membrane Potentials; Neurons, Afferent; Sodium; Structure-Activity Relationship; Thermodynamics; Urea

1994
Increased thermal stability of proteins in the presence of amino acids.
    The Biochemical journal, 1994, Oct-01, Volume: 303 ( Pt 1)

    Topics: Amino Acids; Animals; Arginine; Cytochrome c Group; Drug Stability; Guanidine; Guanidines; Horses; Hot Temperature; Kinetics; Mitochondria, Heart; Proline; Protein Denaturation; Proteins; Thermodynamics

1994
Infrared spectroscopic detection of light-induced change in chloride-arginine interaction in halorhodopsin.
    Biochemistry, 1994, Feb-22, Volume: 33, Issue:7

    Topics: Anions; Arginine; Bacteriorhodopsins; Bromides; Chemical Phenomena; Chemistry, Physical; Chlorides; Electrochemistry; Guanidine; Guanidines; Halorhodopsins; Iodides; Light; Models, Molecular; Spectroscopy, Fourier Transform Infrared

1994
Amino/aromatic interactions in proteins: is the evidence stacked against hydrogen bonding?
    Journal of molecular biology, 1994, Jun-03, Volume: 239, Issue:2

    Topics: Amino Acid Sequence; Amino Acids; Arginine; Asparagine; Benzene; Calorimetry; Guanidine; Guanidines; Histidine; Hydrogen Bonding; Mathematics; Models, Molecular; Phenylalanine; Protein Conformation; Proteins; Tryptophan; Tyrosine

1994
DNA polymerase beta: pre-steady-state kinetic analysis and roles of arginine-283 in catalysis and fidelity.
    Biochemistry, 1996, Jun-04, Volume: 35, Issue:22

    Topics: Animals; Arginine; Base Sequence; Brain; Catalysis; Circular Dichroism; Cloning, Molecular; Deoxyribonucleotides; DNA Polymerase I; Escherichia coli; Guanidine; Guanidines; Kinetics; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Protein Denaturation; Rats; Rats, Sprague-Dawley; Thermodynamics

1996
Assignment of aliphatic side-chain 1HN/15N resonances in perdeuterated proteins.
    Journal of biomolecular NMR, 1996, Volume: 7, Issue:1

    Topics: Amino Acid Sequence; Amino Acids; Arginine; Asparagine; Deuterium; Glutamine; Guanidine; Guanidines; Humans; Hydrogen; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Nitrogen Isotopes; Protein Conformation; Protein Folding; Protein Structure, Secondary; Proteins; Sensitivity and Specificity

1996
Identification of two novel arginine binding DNAs.
    The EMBO journal, 1995, Dec-01, Volume: 14, Issue:23

    Topics: Arginine; Base Sequence; Binding Sites; Chromatography, Affinity; Circular Dichroism; DNA Footprinting; DNA, Single-Stranded; Genes, tat; Guanidine; Guanidines; HIV; HIV Long Terminal Repeat; Humans; Methylation; Molecular Sequence Data; Mutagenesis; Nucleic Acid Conformation; Oligonucleotides; RNA; Sequence Analysis; Single-Strand Specific DNA and RNA Endonucleases

1995
Investigation of refolding condition for Pseudomonas fluorescens lipase by response surface methodology.
    Journal of biotechnology, 1997, May-09, Volume: 54, Issue:3

    Topics: Arginine; Escherichia coli; Gene Expression; Glycerol; Guanidine; Guanidines; Hydrogen-Ion Concentration; Inclusion Bodies; Lipase; Protein Denaturation; Protein Folding; Pseudomonas fluorescens; Recombinant Proteins; Temperature

1997
Differences in the active site environment of Aspergillus ficuum phytases.
    Biochemical and biophysical research communications, 1998, Feb-13, Volume: 243, Issue:2

    Topics: 6-Phytase; Arginine; Aspergillus; Binding Sites; Cyclohexanones; Enzyme Inhibitors; Fungal Proteins; Guanidine; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Phenylglyoxal

1998
Biochemical and histopathological changes in nephrectomized mice.
    Metabolism: clinical and experimental, 1998, Volume: 47, Issue:3

    Topics: Animals; Arginine; Brain; Creatinine; Glycine; Guanidine; Guanidines; Ligation; Male; Mice; Mice, Inbred C57BL; Nephrectomy; Renal Artery; Renal Insufficiency; Succinates

1998
L-arginine binding to liver arginase requires proton transfer to gateway residue His141 and coordination of the guanidinium group to the dimanganese(II,II) center.
    Biochemistry, 1998, Jun-09, Volume: 37, Issue:23

    Topics: Animals; Arginase; Arginine; Asparagine; Binding Sites; Borates; Citrulline; Electron Spin Resonance Spectroscopy; Guanidine; Histidine; Hydrogen-Ion Concentration; Isoleucine; Liver; Lysine; Manganese; Mutagenesis, Site-Directed; Ornithine; Protons; Rats; Substrate Specificity

1998
Salt bridge interactions: stability of the ionic and neutral complexes in the gas phase, in solution, and in proteins.
    Proteins, 1998, Jul-01, Volume: 32, Issue:1

    Topics: Acetates; Arginine; Aspartic Acid; Chloroform; Energy Transfer; Guanidine; Ions; Numerical Analysis, Computer-Assisted; Protein Conformation; Proteins; Solutions; Water

1998
L-Arginine inhibits vasopressin-stimulated mesangial cell Ca2+.
    The American journal of physiology, 1998, Volume: 275, Issue:2

    Topics: Animals; Arginine; Arginine Vasopressin; Calcium; Cell Line, Transformed; Cells, Cultured; Glomerular Mesangium; Guanidine; Mice; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Spermidine; Spermine

1998
Conformational study of a collagen peptide by 1H NMR spectroscopy: observation of the 14N-1H spin-spin coupling of the Arg guanidinium moiety in the triple-helix structure.
    FEBS letters, 1998, Oct-02, Volume: 436, Issue:2

    Topics: Amino Acid Sequence; Animals; Arginine; Cattle; Collagen; Cyanogen Bromide; Guanidine; Humans; Hydrogen; Molecular Sequence Data; Nitrogen; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Protein Conformation

1998
Highly efficient recovery of functional single-chain Fv fragments from inclusion bodies overexpressed in Escherichia coli by controlled introduction of oxidizing reagent--application to a human single-chain Fv fragment.
    Journal of immunological methods, 1998, Oct-01, Volume: 219, Issue:1-2

    Topics: Animals; Antibodies, Monoclonal; Arginine; Disulfides; Escherichia coli; Glutathione; Guanidine; Humans; Immunoglobulin Fragments; Immunoglobulin Variable Region; Inclusion Bodies; Mice; Muramidase; Oxidants; Protein Denaturation; Protein Folding; Recombinant Proteins; Reducing Agents; Rh-Hr Blood-Group System; Solubility

1998
Nitrogen oxides and hydroxyguanidines: formation of donors of nitric and nitrous oxides and possible relevance to nitrous oxide formation by nitric oxide synthase.
    Nitric oxide : biology and chemistry, 1998, Volume: 2, Issue:4

    Topics: Arginine; Chromatography, High Pressure Liquid; Guanidine; Guanidines; Hydroxylamines; Kinetics; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Nitrogen Oxides; Nitrous Oxide; Spectrophotometry

1998
Structural organization of the human eukaryotic initiation factor 5A precursor and its site-directed variant Lys50-->Arg.
    Amino acids, 1999, Volume: 16, Issue:1

    Topics: Amino Acid Substitution; Arginine; Base Sequence; Circular Dichroism; DNA Primers; Eukaryotic Translation Initiation Factor 5A; Fluorescent Dyes; Guanidine; Humans; Lysine; Mutagenesis, Site-Directed; Naphthalenesulfonates; Peptide Initiation Factors; Protein Conformation; Protein Denaturation; Protein Precursors; RNA-Binding Proteins; Spectrophotometry, Ultraviolet

1999
Cysteic- and homocysteic acid-S-(aminoiminomethyl) amides: a new class of modified arginines useful in peptide synthesis.
    The journal of peptide research : official journal of the American Peptide Society, 1999, Volume: 53, Issue:3

    Topics: Amides; Arginine; Cysteic Acid; Guanidine; Models, Chemical; Peptide Biosynthesis

1999
L-arginine binding to nitric-oxide synthase. The role of H-bonds to the nonreactive guanidinium nitrogens.
    The Journal of biological chemistry, 1999, Sep-03, Volume: 274, Issue:36

    Topics: Animals; Arginine; Binding Sites; Cell Line; Guanidine; Hydrogen; Nitric Oxide Synthase; Protein Binding; Rats

1999
Unusual oxidative chemistry of N(omega)-hydroxyarginine and N-hydroxyguanidine catalyzed at an engineered cavity in a heme peroxidase.
    The Journal of biological chemistry, 2000, Mar-24, Volume: 275, Issue:12

    Topics: Arginine; Catalytic Domain; Crystallography, X-Ray; Cytochrome-c Peroxidase; Guanidine; Guanidines; Hemeproteins; Hydrogen Peroxide; Hydroxylamines; Mass Spectrometry; Models, Molecular; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Protein Engineering; Recombinant Proteins; Spectrophotometry, Infrared; Substrate Specificity

2000
[Solid-phase synthesis of peptides containing arginine with an unprotected guanidine group].
    Bioorganicheskaia khimiia, 2000, Volume: 26, Issue:4

    Topics: Arginine; Chromatography, High Pressure Liquid; Guanidine; HIV Envelope Protein gp41; HIV-1; Magnetic Resonance Spectroscopy; Peptide Biosynthesis; Peptides

2000
Bioluminescence color determinants of Phrixothrix railroad-worm luciferases: chimeric luciferases, site-directed mutagenesis of Arg 215 and guanidine effect.
    Photochemistry and photobiology, 2000, Volume: 72, Issue:2

    Topics: Animals; Arginine; Base Sequence; Coleoptera; DNA Primers; Guanidine; Luciferases; Luminescence; Mutagenesis, Site-Directed; Photochemistry; Recombinant Fusion Proteins

2000
The relaxin receptor-binding site geometry suggests a novel gripping mode of interaction.
    The Journal of biological chemistry, 2000, Nov-10, Volume: 275, Issue:45

    Topics: Amino Acid Sequence; Animals; Arginine; Binding Sites; Brain; Chromatography, High Pressure Liquid; Circular Dichroism; Disulfides; Dose-Response Relationship, Drug; Estrogens; Female; Guanidine; Humans; Hydrocarbons; Isoleucine; Kinetics; Methane; Mice; Models, Molecular; Molecular Sequence Data; Peptides; Phenylalanine; Protein Binding; Pubic Symphysis; Receptors, G-Protein-Coupled; Receptors, Peptide; Sequence Homology, Amino Acid; Thermodynamics; Ultraviolet Rays

2000
NMR detection of side chain-side chain hydrogen bonding interactions in 13C/15N-labeled proteins.
    Journal of biomolecular NMR, 2000, Volume: 17, Issue:4

    Topics: Animals; Arginine; Carbon Isotopes; Cattle; Guanidine; Humans; Hydrogen Bonding; Isotope Labeling; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Protein Structure, Secondary; Proteins; Tacrolimus Binding Protein 1A

2000
Evaluation of the role of two conserved active-site residues in beta class glutathione S-transferases.
    The Biochemical journal, 2000, Oct-15, Volume: 351 Pt 2

    Topics: Alanine; Amino Acid Sequence; Anti-Bacterial Agents; Arginine; Asparagine; Binding Sites; Catalysis; Conserved Sequence; Dose-Response Relationship, Drug; Escherichia coli; Glutathione Transferase; Guanidine; Histidine; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Protein Binding; Protein Conformation; Protein Folding; Protein Structure, Secondary; Proteus mirabilis; Rifamycins; Spectrometry, Fluorescence; Temperature; Time Factors

2000
Biochemical basis of type IB (E1beta ) mutations in maple syrup urine disease. A prevalent allele in patients from the Druze kindred in Israel.
    The Journal of biological chemistry, 2001, Sep-28, Volume: 276, Issue:39

    Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Alleles; Arginine; Blotting, Western; Cell Line; Child; Child, Preschool; Chromatography, Gel; Dimerization; Dose-Response Relationship, Drug; Escherichia coli; Family Health; Female; Glutamic Acid; Guanidine; Heterozygote; Homozygote; Humans; Israel; Ketone Oxidoreductases; Kinetics; Male; Maple Syrup Urine Disease; Models, Molecular; Multienzyme Complexes; Mutation; Plasmids; Protein Binding; Sequence Analysis, DNA; Serine; Temperature; Time Factors

2001
The effect of urea and guanidinium chloride on activity of subtilisin Carlsberg.
    Biochimica et biophysica acta, 1971, Dec-28, Volume: 251, Issue:3

    Topics: Arginine; Binding, Competitive; Enzyme Stability; Guanidine; Kinetics; Optical Rotatory Dispersion; Protein Conformation; Protein Denaturation; Subtilisins; Urea; Viscosity

1971
Optimization of a synthetic arginine receptor. Systematic tuning of noncovalent interactions.
    The Journal of organic chemistry, 2001, Aug-24, Volume: 66, Issue:17

    Topics: Arginine; Diphosphonates; Guanidine; Hydrogen Bonding; Kinetics; Models, Chemical; Molecular Conformation; Molecular Mimicry; Receptors, Amino Acid; Static Electricity

2001
N-hydroxyl derivatives of guanidine based drugs as enzymatic NO donors.
    Bioorganic & medicinal chemistry letters, 2001, Sep-03, Volume: 11, Issue:17

    Topics: Animals; Arginine; Dioxanes; Drug Design; Drug Evaluation, Preclinical; Guanidine; Guanidines; Guinea Pigs; Horseradish Peroxidase; Hydrogen Peroxide; In Vitro Techniques; Mesenteric Arteries; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrites; Structure-Activity Relationship; Vasodilator Agents

2001
Role of arginine 59 in the gamma-class carbonic anhydrases.
    Biochemistry, 2002, Jan-15, Volume: 41, Issue:2

    Topics: Amino Acid Sequence; Arginine; Binding Sites; Carbonic Anhydrases; Catalysis; Chromatography; Circular Dichroism; Dimerization; Dose-Response Relationship, Drug; Guanidine; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Molecular Sequence Data; Mutagenesis, Site-Directed; Plasmids; Protein Structure, Secondary; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Thermodynamics

2002
Purification and characterization of two polymorphic variants of short chain acyl-CoA dehydrogenase reveal reduction of catalytic activity and stability of the Gly185Ser enzyme.
    Biochemistry, 2002, Sep-17, Volume: 41, Issue:37

    Topics: Acyl-CoA Dehydrogenase; Acyl-CoA Dehydrogenases; Amino Acid Substitution; Arginine; Catalysis; Chaperonin 10; Chaperonin 60; Circular Dichroism; Enzyme Stability; Escherichia coli; Fatty Acids, Volatile; Genetic Variation; Glycine; Guanidine; Hot Temperature; Humans; Oxidation-Reduction; Polymorphism, Genetic; Protein Denaturation; Protein Folding; Recombinant Proteins; Serine; Spectrophotometry; Tryptophan

2002
Structural and thermodynamic studies on a salt-bridge triad in the NADP-binding domain of glutamate dehydrogenase from Thermotoga maritima: cooperativity and electrostatic contribution to stability.
    Biochemistry, 2002, Dec-31, Volume: 41, Issue:52

    Topics: Alanine; Arginine; Binding Sites; Crystallography, X-Ray; Cysteine; Enzyme Stability; Glutamate Dehydrogenase; Glutamic Acid; Guanidine; Lysine; Mutagenesis, Site-Directed; NADP; Protein Denaturation; Protein Folding; Protein Structure, Tertiary; Recombinant Proteins; Salts; Serine; Static Electricity; Structure-Activity Relationship; Thermodynamics; Thermotoga maritima; Urea

2002
Streptococcus pneumoniae hyaluronate lyase contains two non-cooperative independent folding/unfolding structural domains: characterization of functional domain and inhibitors of enzyme.
    The Journal of biological chemistry, 2003, Jul-11, Volume: 278, Issue:28

    Topics: Arginine; Calcium Chloride; Circular Dichroism; Cloning, Molecular; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Guanidine; Guanidines; Inhibitory Concentration 50; Isothiocyanates; Magnesium Chloride; NG-Nitroarginine Methyl Ester; Polysaccharide-Lyases; Protein Binding; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Spectrometry, Fluorescence; Streptococcus pneumoniae; Temperature

2003
Structural perturbation and enhancement of the chaperone-like activity of alpha-crystallin by arginine hydrochloride.
    Protein science : a publication of the Protein Society, 2003, Volume: 12, Issue:6

    Topics: Animals; Arginine; Cattle; Centrifugation, Density Gradient; Circular Dichroism; Crystallins; Dithiothreitol; Guanidine; Insulin; Protein Conformation; Pyrenes; Solubility; Spectrometry, Fluorescence; Time Factors

2003
Probing of arginine residues in peptides and proteins using selective tagging and electrospray ionization mass spectrometry.
    Journal of mass spectrometry : JMS, 2003, Volume: 38, Issue:8

    Topics: Affinity Labels; Arginine; Guanidine; Peptides; Proteins; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization

2003
[Metabolism of guanidine derivatives. V. Enzymic oxidation of arginine to guanidinobutyramide].
    Biochimica et biophysica acta, 1956, Volume: 22, Issue:1

    Topics: Amidines; Arginine; Guanidine; Guanidines; Oxidation-Reduction; Pregnenes; Streptomyces

1956
Guanidines and phosphagens of semen.
    The Australian journal of experimental biology and medical science, 1958, Volume: 36, Issue:2

    Topics: Arginine; Body Fluids; Creatine; Guanidine; Guanidines; Semen

1958
Inhibition of proteolytic enzymes by decarboxylated amino-acid derivatives. Effect of toluenesulphonyl(tosyl)agmatine (4-toluenesulphonamidobutyl-guanidine) on thrombin trypsin.
    Nature, 1961, May-20, Volume: 190

    Topics: Agmatine; Amidines; Amino Acids; Arginine; Guanidine; Guanidines; Humans; Peptide Hydrolases; Thrombin; Trypsin Inhibitors

1961
[The metabolism of arginine by plant tumor tissues cultivated in vitro].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences, 1962, Nov-12, Volume: 255

    Topics: Arginine; Guanidine; Guanidines; In Vitro Techniques; Plant Tumors; Proteins; Tissue Culture Techniques

1962
[Biogenesis of arcaine in the leech, Hirudo medicinalis L].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1962, Volume: 156

    Topics: Animals; Arginine; Biguanides; Guanidine; Guanidines; Hirudo medicinalis; Humans; Leeches; Leeching

1962
[The metabolism of substituted guanidines in invertebrates].
    Annales de la nutrition et de l'alimentation, 1962, Volume: 16(5)

    Topics: Animals; Arginine; Guanidine; Guanidines; Invertebrates

1962
[Biogenesis of hirudonine].
    Comparative biochemistry and physiology, 1962, Volume: 7

    Topics: Arginine; Guanidine; Guanidines; Spermidine

1962
[METABOLISM OF SULFATED GUANIDINES IN MARINE WORMS].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1963, Aug-31, Volume: 157

    Topics: Animals; Annelida; Arginine; Carbon Isotopes; Chromatography; Guanidine; Guanidines; Helminthiasis; Helminths; Metabolism; Muscle, Smooth; Research; Spectrophotometry

1963
[ON A METHOD OF DETERMINATION OF ARGININE AND GUANIDYL GROUPS IN BIOLOGICAL MEDIA AND IN PROTEINS].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences, 1963, Oct-21, Volume: 257

    Topics: Arginine; Chemistry Techniques, Analytical; Guanidine; Guanidines; Proteins; Research; Tunica Media

1963
[THE PROBLEM OF THE SPECIFICITY OF GUANIDINE FOR THE DEVELOPMENT OF A GUANIDINE-REQUIRING MUTANT OF POLIOVIRUS].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences, 1963, Dec-16, Volume: 257

    Topics: Adenine; Amino Acids; Arginine; Creatine; Creatinine; Enterovirus C, Human; Glycine; Guanidine; Guanidines; Hydrazines; Metabolism; Mutation; Ornithine; Poliovirus; Research; Uracil; Urea

1963
[BIOGENESIS OF 2 SULFURATED GUANIDINES: TAUROCYAMINE AND HYPOTAUROCYAMINE].
    Comparative biochemistry and physiology, 1963, Volume: 10

    Topics: Amidines; Animals; Annelida; Arginine; Body Fluids; Carbon Isotopes; Guanidine; Guanidines; Metabolism; Rats; Research; Sulfur Isotopes; Taurine; Transaminases; Urine

1963
[PAPER CHROMATOGRAPHY OF SEVERAL BIOLOGICALLY IMPORTANT GUANIDINE COMPOUNDS].
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1964, Volume: 335

    Topics: Arginine; Canavanine; Chromatography; Chromatography, Paper; Creatine; Creatinine; Cystine; Guanidine; Guanidines; Isoleucine; Methionine; Research; Serine; Streptomycin; Tryptophan; Valine

1964
[REMARKS ON ISATIN-BETA-THIOSEMICARBAZONE AND ON SEVERAL INHIBITORS OF VIRAL DEVELOPMENT].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences, 1964, Feb-10, Volume: 258

    Topics: Antiviral Agents; Arginine; Citrulline; Creatine; Creatinine; Enterovirus C, Human; Glutamine; Glycine; Guanidine; Guanidines; Indoles; Isatin; Mutation; Ornithine; Pharmacology; Poliovirus; Thiosemicarbazones; Thiourea; Uracil; Urea

1964
[BIOGENESIS OF DELTA-GUANIDOVALERIANIC ACID].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1964, Volume: 158

    Topics: Arginine; Chromatography; Guanidine; Guanidines; Hypnotics and Sedatives; Metabolism; Rats; Research; Valerian

1964
[FORMATION OF GAMMA-GUANIDINOBUTYRIC ACID FROM ARGININE IN THE WHITE RAT].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences, 1964, Apr-20, Volume: 258

    Topics: Arginine; Body Fluids; Butyrates; Guanidine; Guanidines; Metabolism; Rats; Research; Urine

1964
BIOSYNTHESIS OF STREPTOMYCIN. I. ORIGIN OF THE GUANIDINE GROUP.
    The Journal of biological chemistry, 1964, Volume: 239

    Topics: Amidohydrolases; Arginine; Carbon Isotopes; Guanidine; Guanidines; Metabolism; Research; Streptomyces; Streptomycin

1964
[ACTIVE SITES OF L-ARGININE DECARBOXY-OXIDASE].
    Biochimica et biophysica acta, 1964, Jun-01, Volume: 85

    Topics: Amidines; Amino Acid Oxidoreductases; Arginine; Benzoates; Catalytic Domain; Chloromercuribenzoates; Enzyme Inhibitors; Glutathione; Guanidine; Guanidines; Manometry; Oxidoreductases; Oxygen; Oxygenases; Research

1964
ON THE ACTIVATION OF TRYPSIN BY AMINES.
    Biochimica et biophysica acta, 1964, Jun-01, Volume: 85

    Topics: Amines; Arginine; Catalysis; Ethylamines; Glycine; Guanidine; Guanidines; Kinetics; Research; Trypsin

1964
THE DISTRIBUTION OF GUANIDINE-ADENOSINE TRIPHOSPHATE PHOSPHOTRANSFERASES AND ADENOSINE TRIPHOSPHATASE IN ANIMALS FROM SEVERAL PHYLA.
    Comparative biochemistry and physiology, 1964, Volume: 13

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Amines; Animals; Annelida; Arginine; Cnidaria; Creatine; Creatinine; Crustacea; Electrophoresis; Guanidine; Guanidines; Mollusca; Muscles; Phosphotransferases; Physiology, Comparative; Platyhelminths; Research

1964
[ON THE PRESENCE OF OCTINE IN CROWN-GALL].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences, 1964, Dec-21, Volume: 259

    Topics: Arginase; Arginine; Carbon Isotopes; Chromatography; Crowns; Guanidine; Guanidines; Plant Tumors; Research

1964
[STUDY OF THE ACTION OF VARIOUS AMINO ACIDS ON THE DEAMIDINATION OF GAMMA-GUANIDOBUTYRIC ACID AND ARGININE BY THE RAY LIVER].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1964, Volume: 158

    Topics: Amidohydrolases; Amino Acids; Aminobutyrates; Animals; Arginine; Butyrates; Chemical Phenomena; Chemistry; Enzyme Inhibitors; Fishes; Glycine; Guanidine; Guanidines; Liver; Lysine; Ornithine; Pharmacology; Research

1964
SEARCH FOR A PHOSPHAGEN IN TETRAHYMENA PYRIFORMIS.
    Comparative biochemistry and physiology, 1965, Volume: 14

    Topics: Adenosine Triphosphatases; Arginine; Biochemical Phenomena; Biochemistry; Chemical Phenomena; Chemistry; Chemistry Techniques, Analytical; Chromatography; Coenzymes; Decamethonium Compounds; Guanidine; Guanidines; Histidine; Phosphates; Phosphocreatine; Research; Tetrahymena; Tetrahymena pyriformis

1965
TRANSAMIDINASE OF HOG KIDNEY. II. ISOLATION OF A STABLE ENZYME-AMIDINE COMPLEX.
    The Journal of biological chemistry, 1965, Volume: 240

    Topics: Amidines; Amidinotransferases; Animals; Arginine; Biochemical Phenomena; Biochemistry; Chromatography; Guanidine; Guanidines; Kidney; Research; Swine; Transferases

1965
STUDIES OF SOME SUBSTANCES WITH ANTIVIRAL ACTIVITY. I. THE INHIBITORY EFFECT OF GUANIDINE ON THE GROWTH OF HERPES SIMPLEX VIRUS IN HUMAN EMBRYONIC KIDNEY CELL CULTURES.
    Pathologia et microbiologia, 1965, Volume: 28

    Topics: Antiviral Agents; Arginine; Creatine; Creatinine; Cytopathogenic Effect, Viral; DNA; DNA, Viral; Guanidine; Guanidines; Pharmacology; Research; Simplexvirus; Thiourea; Tissue Culture Techniques; Urea; Virus Cultivation

1965
Modulating calcitonin fibrillogenesis: an antiparallel alpha-helical dimer inhibits fibrillation of salmon calcitonin.
    The Journal of biological chemistry, 2004, Feb-20, Volume: 279, Issue:8

    Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Animals; Arginine; Calcitonin; Chromatography, Gel; Circular Dichroism; Dimerization; Dose-Response Relationship, Drug; Guanidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Leucine; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Peptides; Proline; Protein Folding; Protein Structure, Secondary; Salmon; Sequence Homology, Amino Acid

2004
The guanidine like effects of arginine on aminoacylase and salt-induced molten globule state.
    The international journal of biochemistry & cell biology, 2004, Volume: 36, Issue:2

    Topics: Amidohydrolases; Animals; Arginine; Dose-Response Relationship, Drug; Guanidine; Ions; Kidney; Potassium Chloride; Protein Binding; Protein Conformation; Protein Folding; Salts; Spectrometry, Fluorescence; Swine; Zinc

2004
Solubilization of active green fluorescent protein from insoluble particles by guanidine and arginine.
    Biochemical and biophysical research communications, 2003, Dec-26, Volume: 312, Issue:4

    Topics: Arginine; Escherichia coli; Green Fluorescent Proteins; Guanidine; Inclusion Bodies; Luminescent Proteins; Particle Size; Protein Folding; Recombinant Proteins; Solubility

2003
A novel lipid hydroperoxide-derived modification to arginine.
    Chemical research in toxicology, 2003, Volume: 16, Issue:12

    Topics: Aldehydes; Arginine; Borohydrides; Chromatography, Liquid; Guanidine; Lipid Peroxides; Mass Spectrometry; Nuclear Magnetic Resonance, Biomolecular; Oligopeptides; Oxidation-Reduction

2003
High-level expression and one-step purification of recombinant dengue virus type 2 envelope domain III protein in Escherichia coli.
    Protein expression and purification, 2004, Volume: 33, Issue:1

    Topics: Animals; Arginine; Blotting, Western; Cell Line; Chromatography, Affinity; Cricetinae; Dengue Virus; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Guanidine; Plasmids; Protein Renaturation; Protein Structure, Tertiary; Recombinant Proteins; Viral Envelope Proteins; Viral Plaque Assay

2004
Esters of mandelic acid as substrates for (S)-mandelate dehydrogenase from Pseudomonas putida: implications for the reaction mechanism.
    Biochemistry, 2004, Feb-24, Volume: 43, Issue:7

    Topics: Alcohol Oxidoreductases; Amino Acid Substitution; Arginine; Carboxylic Acids; Esters; Flavin Mononucleotide; Glycine; Guanidine; Hydrolysis; Imidazoles; Kinetics; Mandelic Acids; Methylguanidine; Pseudomonas putida; Substrate Specificity

2004
Role of Arg-72 of pharaonis Phoborhodopsin (sensory rhodopsin II) on its photochemistry.
    Biophysical journal, 2004, Volume: 86, Issue:5

    Topics: Arginine; Bacteriorhodopsins; Chlorine; Guanidine; Hydrogen-Ion Concentration; Ions; Light; Mutation; Phosphatidylcholines; Photochemistry; Photolysis; Proton Pumps; Protons; Recombinant Proteins; Rhodopsin; Time Factors

2004
Characterization of bis(levuglandinyl) urea derivatives as products of the reaction between prostaglandin H2 and arginine.
    Biochemistry, 2004, May-11, Volume: 43, Issue:18

    Topics: Aldehydes; Amyloid beta-Peptides; Arginine; Guanidine; Histones; Humans; Lysine; Ornithine; Peptide Fragments; Prostaglandin H2; Prostaglandins E; Schiff Bases; Serum Albumin; Spectrometry, Mass, Electrospray Ionization; Urea

2004
NMR detection of intermolecular NH.OP hydrogen bonds between guanidinium protons and bisposphonate moieties in an artificial arginine receptor.
    Journal of the American Chemical Society, 2004, Aug-25, Volume: 126, Issue:33

    Topics: Arginine; Cold Temperature; Diphosphonates; Guanidine; Hydrogen Bonding; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Receptors, Amino Acid

2004
Modeling of the gas-phase ion chemistry of protonated arginine.
    Journal of mass spectrometry : JMS, 2004, Volume: 39, Issue:9

    Topics: Ammonia; Arginine; Gases; Guanidine; Ions; Models, Molecular; Molecular Conformation; Protons; Thermodynamics

2004
Improved high-performance liquid chromatographic determination of guanidino compounds by precolumn dervatization with ninhydrin and fluorescence detection.
    Journal of separation science, 2004, Volume: 27, Issue:15-16

    Topics: Arginine; Blood; Chromatography, High Pressure Liquid; Guanidine; Molecular Structure; Ninhydrin; Spectrometry, Fluorescence; Temperature

2004
Structural and kinetic analyses of arginine residues in the active site of the acetate kinase from Methanosarcina thermophila.
    The Journal of biological chemistry, 2005, Mar-18, Volume: 280, Issue:11

    Topics: Acetate Kinase; Acetates; Adenosine Diphosphate; Adenosine Triphosphate; Arginine; Binding Sites; Catalysis; Crystallography, X-Ray; Dose-Response Relationship, Drug; Electrons; Guanidine; Hydrogen-Ion Concentration; Hydroxylamine; Kinetics; Methanosarcina; Models, Chemical; Models, Molecular; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Stereoisomerism; Threonine

2005
Design and synthesis of a new class of arginine analogues with an improved anion binding site in the side chain.
    Chemical communications (Cambridge, England), 2005, Feb-14, Issue:6

    Topics: Anions; Arginine; Binding Sites; Drug Design; Guanidine; Pyrroles

2005
Voltage-sensing arginines in a potassium channel permeate and occlude cation-selective pores.
    Neuron, 2005, Feb-03, Volume: 45, Issue:3

    Topics: Amino Acid Substitution; Animals; Arginine; Cations; Cell Membrane; Female; Guanidine; Ion Channel Gating; Membrane Potentials; Mutagenesis, Site-Directed; Oocytes; Potassium Channels; Protein Conformation; Protein Structure, Tertiary; Shaker Superfamily of Potassium Channels; Structure-Activity Relationship; Xenopus laevis

2005
Effects of conformational stability and geometry of guanidinium display on cell entry by beta-peptides.
    Journal of the American Chemical Society, 2005, Mar-23, Volume: 127, Issue:11

    Topics: Arginine; Endocytosis; Guanidine; HeLa Cells; Humans; Oligopeptides; Protein Conformation; Protein Structure, Secondary; Structure-Activity Relationship

2005
Role of arginine in the stabilization of proteins against aggregation.
    Biochemistry, 2005, Mar-29, Volume: 44, Issue:12

    Topics: Animals; Antibodies, Monoclonal; Arginine; Carbonic Anhydrases; Cattle; Dipeptides; Guanidine; Humans; Insulin; Insulin Antibodies; Kinetics; Models, Chemical; Protein Denaturation; Protein Folding; Proteins; Sodium Chloride; Solutions; Thermodynamics

2005
A mitochondrial cytochrome b mutation causing severe respiratory chain enzyme deficiency in humans and yeast.
    The FEBS journal, 2005, Volume: 272, Issue:14

    Topics: Adult; Amino Acid Sequence; Animals; Arginine; Base Sequence; Biopsy; Cytochromes b; DNA, Mitochondrial; Female; Guanidine; Humans; Mitochondrial Diseases; Models, Molecular; Molecular Sequence Data; Muscles; Mutation; Protein Structure, Quaternary; Protein Subunits; Saccharomyces cerevisiae

2005
Effects of energy restriction and fish oil supplementation on renal guanidino levels and antioxidant defences in aged lupus-prone B/W mice.
    The British journal of nutrition, 2005, Volume: 93, Issue:6

    Topics: Acetic Acid; Aging; Animals; Antioxidants; Arginine; Catalase; Creatinine; Dietary Supplements; Energy Intake; Female; Fish Oils; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Guanidine; Kidney; Lupus Vulgaris; Mice; Mice, Inbred Strains; Oxidative Stress; Reactive Oxygen Species; Superoxide Dismutase

2005
Methylation of the guanidino group of arginine residues prevents citrullination by peptidylarginine deiminase IV.
    FEBS letters, 2005, Aug-01, Volume: 579, Issue:19

    Topics: Arginine; Catalysis; Chromatography, High Pressure Liquid; Citrulline; Guanidine; Hydrolases; Methylation; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity

2005
Crystal structures representing the Michaelis complex and the thiouronium reaction intermediate of Pseudomonas aeruginosa arginine deiminase.
    The Journal of biological chemistry, 2005, Oct-07, Volume: 280, Issue:40

    Topics: Apoenzymes; Arginine; Catalytic Domain; Crystallization; Guanidine; Hydrolases; Hydrolysis; Kinetics; Macromolecular Substances; Protein Conformation; Protons; Pseudomonas aeruginosa; Substrate Specificity

2005
Effective elution of antibodies by arginine and arginine derivatives in affinity column chromatography.
    Analytical biochemistry, 2005, Oct-15, Volume: 345, Issue:2

    Topics: Animals; Antibodies; Antibodies, Monoclonal; Arginine; Chromatography, Affinity; Citric Acid; Guanidine; Humans; Hydrogen-Ion Concentration; Immunoglobulin G; Mice; Staphylococcal Protein A

2005
Structure-sweetness relationship in egg white lysozyme: role of lysine and arginine residues on the elicitation of lysozyme sweetness.
    Chemical senses, 2005, Volume: 30, Issue:8

    Topics: Amino Acid Substitution; Amino Acids, Basic; Animals; Arginine; Egg Proteins; Escherichia coli; Gene Expression Regulation, Enzymologic; Guanidine; Lysine; Models, Molecular; Muramidase; Mutagenesis, Site-Directed; Structure-Activity Relationship; Sweetening Agents; Taste

2005
Guanidine derivatives rescue the Arg418Ala mutation of Tritrichomonas foetus IMP dehydrogenase.
    Biochemistry, 2005, Dec-20, Volume: 44, Issue:50

    Topics: Alanine; Animals; Arginine; Guanidine; IMP Dehydrogenase; Kinetics; Mutagenesis, Site-Directed; Tritrichomonas foetus

2005
Protein stabilization by specific binding of guanidinium to a functional arginine-binding surface on an SH3 domain.
    Protein science : a publication of the Protein Society, 2006, Volume: 15, Issue:1

    Topics: Animals; Arginine; Binding Sites; Guanidine; Kinetics; Magnetic Resonance Spectroscopy; Mutation; Peptides; Protein Binding; Protein Denaturation; Proto-Oncogene Proteins c-fyn; Sodium Chloride; src Homology Domains; Surface Properties; Thermodynamics; Urea

2006
Characterization of arginine as a solvent additive: a halophilic enzyme as a model protein.
    Protein and peptide letters, 2005, Volume: 12, Issue:7

    Topics: Arginine; Enzyme Stability; Guanidine; Halobacterium salinarum; Hot Temperature; Models, Biological; Nucleoside-Diphosphate Kinase; Protein Denaturation; Protein Folding; Sodium Chloride; Solvents

2005
The crystal structure of the R52Q mutant demonstrates a role for R52 in chromophore pKa regulation in photoactive yellow protein.
    Biochemistry, 2006, Mar-21, Volume: 45, Issue:11

    Topics: Arginine; Bacterial Proteins; Crystallography, X-Ray; Escherichia coli; Gene Expression Regulation; Glutamine; Guanidine; Hydrogen Bonding; Kinetics; Models, Molecular; Photoreceptors, Microbial; Protein Conformation; Water

2006
Gaseous bradykinin and its singly, doubly, and triply protonated forms: a first-principles study.
    The journal of physical chemistry. B, 2006, Apr-13, Volume: 110, Issue:14

    Topics: Arginine; Bradykinin; Chemical Phenomena; Chemistry, Physical; Computer Simulation; Gases; Guanidine; Hydrogen; Hydrogen Bonding; Models, Molecular; Monte Carlo Method; Nitrogen; Oxygen; Protons

2006
Stereochemistry of guanidine-metal interactions: implications for L-arginine-metal interactions in protein structure and function.
    Proteins, 2006, Nov-15, Volume: 65, Issue:3

    Topics: Arginine; Binding Sites; Guanidine; Humans; Hydrogen Bonding; Metals, Heavy; Models, Molecular; Molecular Conformation; Protein Conformation; Proteins; Stereoisomerism; Structure-Activity Relationship

2006
Variation in proton affinity of the guanidino group between free and blocked arginine.
    Amino acids, 2007, Volume: 33, Issue:1

    Topics: Arginine; Guanidine; Peptide Fragments; Phosphorylation; Protons; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2007
Aggregation suppression of proteins by arginine during thermal unfolding.
    Protein and peptide letters, 2006, Volume: 13, Issue:9

    Topics: Antibodies, Monoclonal; Arginine; Calorimetry, Differential Scanning; Circular Dichroism; Guanidine; Humans; Interleukin-6; Protein Conformation; Protein Denaturation; Temperature

2006
Enhancement of MALDI-MS spectra of C-terminal peptides by the modification of proteins via an active ester generated in situ from an oxazolone.
    Analytical chemistry, 2006, Nov-15, Volume: 78, Issue:22

    Topics: Acetic Anhydrides; Amides; Amino Acid Sequence; Arginine; Aspartic Acid; Esters; Fluorobenzenes; Formates; Glutamic Acid; Guanidine; Hydrazines; Imidazoles; Molecular Sequence Data; Oxazolone; Peptides; Phenols; Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2006
A novel arginine kinase with substrate specificity towards D-arginine.
    The protein journal, 2007, Volume: 26, Issue:5

    Topics: Adenosine Monophosphate; Amino Acid Sequence; Animals; Arginine; Arginine Kinase; Cloning, Molecular; Evolution, Molecular; Guanidine; Molecular Sequence Data; Phylogeny; Polychaeta; Recombinant Proteins; Substrate Specificity

2007
Arginine-mimic labeling with guanidinoethanethiol to increase mass sensitivity of lysine-terminated phosphopeptides by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
    Rapid communications in mass spectrometry : RCM, 2007, Volume: 21, Issue:14

    Topics: Arginine; Guanidine; Lysine; Peptide Mapping; Phosphopeptides; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Staining and Labeling; Sulfhydryl Compounds

2007
Phosphate-mediated arginine insertion into lipid membranes and pore formation by a cationic membrane peptide from solid-state NMR.
    Journal of the American Chemical Society, 2007, Sep-19, Volume: 129, Issue:37

    Topics: Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Arginine; Guanidine; Hydrogen Bonding; Lipid Bilayers; Magnetic Resonance Spectroscopy; Membrane Proteins; Models, Molecular; Organophosphates; Phosphatidylethanolamines; Phosphatidylglycerols; Protein Conformation; Proteins

2007
Implementation of a k/k(0) method to identify long-range structure in transition states during conformational folding/unfolding of proteins.
    Structure (London, England : 1993), 2007, Volume: 15, Issue:10

    Topics: Alanine; Animals; Arginine; Cattle; Crystallography, X-Ray; Guanidine; Hydrogen-Ion Concentration; Kinetics; Protein Conformation; Protein Denaturation; Protein Folding; Ribonuclease, Pancreatic; Structure-Activity Relationship; Thermodynamics; Valine

2007
A terphenyl scaffold for pi-stacked guanidinium recognition elements.
    Organic letters, 2008, Jan-17, Volume: 10, Issue:2

    Topics: Arginine; Carboxylic Acids; Guanidine; Models, Molecular; Molecular Conformation; Molecular Structure; Proteins; Terphenyl Compounds

2008
The effect of small molecules in modulating the chaperone activity of alphaB-crystallin against ordered and disordered protein aggregation.
    The FEBS journal, 2008, Volume: 275, Issue:5

    Topics: alpha-Crystallin B Chain; alpha-Synuclein; Amyloid; Animals; Arginine; Caseins; Cattle; Cytoprotection; Guanidine; Hot Temperature; Humans; Insulin; Lactalbumin; Mutation; Parkinson Disease

2008
Gas-phase protonation thermochemistry of arginine.
    The journal of physical chemistry. B, 2008, Mar-20, Volume: 112, Issue:11

    Topics: Algorithms; Arginine; Gases; Guanidine; Kinetics; Models, Molecular; Protons; Spectrometry, Mass, Electrospray Ionization; Thermodynamics

2008
Effects of guanidinium-phosphate hydrogen bonding on the membrane-bound structure and activity of an arginine-rich membrane peptide from solid-state NMR spectroscopy.
    Angewandte Chemie (International ed. in English), 2008, Volume: 47, Issue:17

    Topics: Arginine; Guanidine; Hydrogen Bonding; Lipid Bilayers; Magnetic Resonance Spectroscopy; Molecular Structure; Peptides; Phosphates

2008
Protein crystallography through supramolecular interactions between a lanthanide complex and arginine.
    Angewandte Chemie (International ed. in English), 2008, Volume: 47, Issue:18

    Topics: Animals; Arginine; Crystallography, X-Ray; Guanidine; Lanthanoid Series Elements; Muramidase; Picolinic Acids; Protein Conformation; Proteins

2008
Critical role of arginine 160 of the EutB protein subunit for active site structure and radical catalysis in coenzyme B12-dependent ethanolamine ammonia-lyase.
    Biochemistry, 2008, May-20, Volume: 47, Issue:20

    Topics: Arginine; Bacterial Proteins; Binding Sites; Catalysis; Cobamides; Crystallography, X-Ray; Electron Spin Resonance Spectroscopy; Enzyme Activation; Ethanolamine Ammonia-Lyase; Free Radicals; Guanidine; Kinetics; Models, Molecular; Mutation; Protein Structure, Tertiary; Protein Subunits; Salmonella typhimurium; Structural Homology, Protein; Substrate Specificity

2008
Understanding the role of Arg96 in structure and stability of green fluorescent protein.
    Proteins, 2008, Nov-15, Volume: 73, Issue:3

    Topics: Amino Acid Substitution; Arginine; Bacteria; Green Fluorescent Proteins; Guanidine; Kinetics; Models, Molecular; Mutant Proteins; Protein Conformation; Protein Folding; Solvents; Spectrometry, Fluorescence; Structure-Activity Relationship; Thermodynamics; Tryptophan

2008
Experimental evidence for an inverse hydrogen migration in arginine radicals.
    Journal of the American Chemical Society, 2008, Jun-18, Volume: 130, Issue:24

    Topics: Arginine; Cesium; Electron Transport; Free Radicals; Guanidine; Hydrogen; Kinetics; Oxidation-Reduction; Peptides

2008
Two-photon microscopy study of the intracellular compartmentalisation of emissive terbium complexes and their oligo-arginine and oligo-guanidinium conjugates.
    Chemical communications (Cambridge, England), 2008, Jun-07, Issue:21

    Topics: Animals; Apoptosis; Arginine; Cell Compartmentation; Dose-Response Relationship, Drug; Fibroblasts; Guanidine; HeLa Cells; Humans; Ligands; Mice; Microscopy, Fluorescence; Mitochondria; Molecular Conformation; NIH 3T3 Cells; Organometallic Compounds; Peptides; Photons; Serum Albumin; Skin; Stereoisomerism; Terbium

2008
Insights into the post-translational methylation of arginine from studies of guanidinium-water nanodroplets.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2008, Volume: 14, Issue:21

    Topics: Arginine; Gases; Guanidine; Hydrogen Bonding; Methylation; Models, Chemical; Nanostructures; Protein Processing, Post-Translational; Spectrometry, Mass, Electrospray Ionization; Water

2008
Arginine increases the solubility of coumarin: comparison with salting-in and salting-out additives.
    Journal of biochemistry, 2008, Volume: 144, Issue:3

    Topics: Arginine; Benzyl Alcohols; Biochemistry; Caffeine; Coumarins; Dose-Response Relationship, Drug; Guanidine; Hydrogen-Ion Concentration; Models, Biological; Salts; Solubility; Surface Properties; Urea; Water

2008
Electrostatics-defying interaction between arginine termini as a thermodynamic driving force in protein-protein interaction.
    Proteins, 2009, Volume: 74, Issue:1

    Topics: Arginine; Computer Simulation; Guanidine; Hydrogen Bonding; Ligands; Models, Molecular; Protein Folding; Protein Multimerization; Proteins; Quantum Theory; Solvents; Static Electricity; Thermodynamics

2009
Diastereoselective functionalizations of enecarbamates derived from pipecolic acid towards 5-guanidinopipecolates as arginine mimetics.
    Organic & biomolecular chemistry, 2008, Sep-21, Volume: 6, Issue:18

    Topics: Amines; Arginine; Azides; Biomimetic Materials; Carbamates; Enzyme Inhibitors; Guanidine; Hydroxylation; Ketones; Molecular Structure; Nitric Oxide Synthase; Oxidation-Reduction; Pipecolic Acids; Stereoisomerism

2008
Inhibitory effect of stilbamidine guanidine and arginine on glycolysis.
    Federation proceedings, 1948, Volume: 7, Issue:1 Pt 1

    Topics: Arginine; Glycolysis; Guanidine; Guanidines; Stilbamidines

1948
Studies on the functional significance of a C-terminal S-shaped motif in human arginase type I: essentiality for cooperative effects.
    Archives of biochemistry and biophysics, 2009, Jan-01, Volume: 481, Issue:1

    Topics: Amino Acid Motifs; Arginase; Arginine; Guanidine; Humans; Hydrogen-Ion Concentration; Mutation; Recombinant Proteins

2009
Guanidine-acylguanidine bioisosteric approach in the design of radioligands: synthesis of a tritium-labeled N(G)-propionylargininamide ([3H]-UR-MK114) as a highly potent and selective neuropeptide Y Y1 receptor antagonist.
    Journal of medicinal chemistry, 2008, Dec-25, Volume: 51, Issue:24

    Topics: Animals; Arginine; Binding Sites; Cell Line, Tumor; Chemistry, Pharmaceutical; CHO Cells; Chromatography, High Pressure Liquid; Cricetinae; Cricetulus; Drug Design; Guanidine; Humans; Kinetics; Receptors, Neuropeptide Y; Tritium

2008
Investigation of cosolute-protein preferential interaction coefficients: new insight into the mechanism by which arginine inhibits aggregation.
    The journal of physical chemistry. B, 2009, Feb-19, Volume: 113, Issue:7

    Topics: Arginine; Chymotrypsinogen; Glucose; Glycerol; Guanidine; Muramidase; Osmolar Concentration; Particle Size; Pressure; Serum Albumin, Bovine; Solutions; Urea; Volatilization

2009
Cooperative effects of urea and L-arginine on protein refolding.
    Protein expression and purification, 2009, Volume: 66, Issue:1

    Topics: Arginine; Granulocyte Colony-Stimulating Factor; Guanidine; Humans; Protein Conformation; Protein Folding; Recombinant Proteins; Urea

2009
In silico molecular engineering for a targeted replacement in a tumor-homing peptide.
    The journal of physical chemistry. B, 2009, Jun-04, Volume: 113, Issue:22

    Topics: Amino Acid Sequence; Amino Acid Substitution; Arginine; Computer Simulation; Guanidine; Models, Molecular; Oligopeptides; Proline; Protein Conformation

2009
Role of guanidinium group in the insertion of l-arginine in DMPE and DMPC lipid interphases.
    Biochimica et biophysica acta, 2010, Volume: 1798, Issue:3

    Topics: 2-Naphthylamine; Anisotropy; Arginine; Dimyristoylphosphatidylcholine; Electricity; Guanidine; Laurates; Liposomes; Phosphatidylethanolamines; Pressure; Surface Properties

2010
Role of arginine guanidinium moiety in nitric-oxide synthase mechanism of oxygen activation.
    The Journal of biological chemistry, 2010, Mar-05, Volume: 285, Issue:10

    Topics: Animals; Arginine; Binding Sites; Catalytic Domain; Citrulline; Enzyme Activation; Guanidine; Heme; Hydrogen Bonding; Mice; Models, Molecular; Molecular Structure; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidation-Reduction; Oxygen; Reactive Nitrogen Species; Reactive Oxygen Species; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman

2010
Activation of R235A mutant orotidine 5'-monophosphate decarboxylase by the guanidinium cation: effective molarity of the cationic side chain of Arg-235.
    Biochemistry, 2010, Feb-09, Volume: 49, Issue:5

    Topics: Alanine; Amino Acid Substitution; Arginine; Catalysis; Cations, Monovalent; Enzyme Activation; Enzyme Stability; Fungal Proteins; Guanidine; Orotidine-5'-Phosphate Decarboxylase; Protein Binding; Protein Subunits

2010
Novel vitamin D receptor ligands having a carboxyl group as an anchor to arginine 274 in the ligand-binding domain.
    The Journal of steroid biochemistry and molecular biology, 2010, Volume: 121, Issue:1-2

    Topics: Animals; Arginine; Calcifediol; Cattle; Crystallography, X-Ray; Drug Evaluation, Preclinical; Guanidine; Humans; Hydrogen Bonding; Ligands; Mutation; Protein Structure, Tertiary; Receptors, Calcitriol; Static Electricity; Vitamin D

2010
L-arginine hydrochloride increases the solubility of folded and unfolded recombinant plasminogen activator rPA.
    Protein science : a publication of the Protein Society, 2010, Volume: 19, Issue:9

    Topics: Arginine; Circular Dichroism; Guanidine; Methylation; Plasminogen Activators; Protein Denaturation; Protein Folding; Recombinant Proteins; Solubility

2010
Identification of arginine residues in peptides by 2D-IR echo spectroscopy.
    The journal of physical chemistry. A, 2011, Sep-01, Volume: 115, Issue:34

    Topics: Arginine; Chemistry, Physical; Deuterium Oxide; Dipeptides; Energy Transfer; Guanidine; Kinetics; Protein Structure, Secondary; Spectrophotometry, Infrared; Spectroscopy, Fourier Transform Infrared; Vibration; Viral Matrix Proteins

2011
Investigating the cationic side chains of the antimicrobial peptide tritrpticin: hydrogen bonding properties govern its membrane-disruptive activities.
    Biochimica et biophysica acta, 2011, Volume: 1808, Issue:9

    Topics: Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Arginine; Bacillus subtilis; Cations; Erythrocytes; Escherichia coli; Guanidine; Hemolysis; Humans; Hydrogen Bonding; Lysine; Membranes; Methylation; Oligopeptides; Peptides; Spectrometry, Fluorescence; Staphylococcus aureus

2011
Application of the guanidine-acylguanidine bioisosteric approach to argininamide-type NPY Y₂ receptor antagonists.
    ChemMedChem, 2011, Sep-05, Volume: 6, Issue:9

    Topics: Acylation; Animals; Arginine; Binding Sites; CHO Cells; Cricetinae; Cricetulus; Flow Cytometry; Guanidine; Humans; Kinetics; Receptors, Neuropeptide Y; Structure-Activity Relationship

2011
[³H]UR-MK136: a highly potent and selective radioligand for neuropeptide Y Y₁ receptors.
    ChemMedChem, 2011, Sep-05, Volume: 6, Issue:9

    Topics: Acetylation; Arginine; Cell Line; Diphenylacetic Acids; Guanidine; Humans; Kinetics; Neuroblastoma; Radioligand Assay; Receptors, Neuropeptide Y; Structure-Activity Relationship; Tritium

2011
Backbone rigidity and static presentation of guanidinium groups increases cellular uptake of arginine-rich cell-penetrating peptides.
    Nature communications, 2011, Aug-30, Volume: 2

    Topics: Animals; Arginine; Biological Transport; Cell Line; Cell Membrane; Cell-Penetrating Peptides; Cells; Guanidine; Kinetics; Mice; Molecular Structure

2011
On-resin synthesis of novel arginine-isostere peptides bearing substituted amidine headgroups.
    Journal of peptide science : an official publication of the European Peptide Society, 2012, Volume: 18, Issue:1

    Topics: Amidines; Arginine; Biological Products; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Guanidine; Mesylates; Peptides; Resins, Synthetic; Solid-Phase Synthesis Techniques; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Stereoisomerism; Thioamides; Trifluoroacetic Acid; Trimethylsilyl Compounds

2012
Arginine residues at internal positions in a protein are always charged.
    Proceedings of the National Academy of Sciences of the United States of America, 2011, Nov-22, Volume: 108, Issue:47

    Topics: Arginine; Guanidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Micrococcal Nuclease; Models, Molecular; Protein Conformation; Static Electricity; Thermodynamics; Water

2011
The early life of a peptide cation-radical. Ground and excited-state trajectories of electron-based peptide dissociations during the first 330 femtoseconds.
    Journal of the American Society for Mass Spectrometry, 2012, Volume: 23, Issue:3

    Topics: Arginine; Cations; Free Radicals; Guanidine; Isomerism; Mass Spectrometry; Peptides; Thermodynamics

2012
Arginine mimetics using α-guanidino acids: introduction of functional groups and stereochemistry adjacent to recognition guanidiniums in peptides.
    Chembiochem : a European journal of chemical biology, 2012, Jan-23, Volume: 13, Issue:2

    Topics: Amino Acids; Arginine; Circular Dichroism; Guanidine; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Peptides; Protein Structure, Tertiary; Stereoisomerism

2012
Sidedness of interfacial arginine residues and anti-atherogenicity of apolipoprotein A-I mimetic peptides.
    Journal of lipid research, 2012, Volume: 53, Issue:5

    Topics: Animals; Apolipoprotein A-I; Arginine; Aryldialkylphosphatase; Atherosclerosis; Chemical Phenomena; Cholesterol; Female; Gene Deletion; Guanidine; Humans; Lipoproteins, HDL; Mice; Oxidation-Reduction; Peptidomimetics; Phosphatidylcholines; Protein Structure, Secondary; Protein Unfolding; Reactive Oxygen Species; Unilamellar Liposomes

2012
Unusual arginine formations in protein function and assembly: rings, strings, and stacks.
    The journal of physical chemistry. B, 2012, Jun-14, Volume: 116, Issue:23

    Topics: Arginine; Guanidine; Hydrogen Bonding; Ligands; Models, Molecular; Protein Binding; Proteins; Static Electricity; Water

2012
Selective mode of action of guanidine-containing non-peptides at human NPFF receptors.
    Journal of medicinal chemistry, 2012, Jul-12, Volume: 55, Issue:13

    Topics: Adamantane; Amino Acid Substitution; Animals; Arginine; Binding Sites; Biological Assay; Chlorocebus aethiops; COS Cells; Dipeptides; Drug Design; Guanidine; HEK293 Cells; Humans; Ligands; Microscopy, Fluorescence; Molecular Conformation; Peptidomimetics; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Structure-Activity Relationship

2012
Arginine-rich self-assembling peptides as potent antibacterial gels.
    Biomaterials, 2012, Volume: 33, Issue:35

    Topics: Anti-Bacterial Agents; Arginine; Circular Dichroism; Drug Resistance, Multiple, Bacterial; Gram-Negative Bacteria; Gram-Positive Bacteria; Guanidine; Hemolytic Agents; Hydrogels; Lysine; Microbial Viability; Microscopy, Atomic Force; Peptides; Structure-Activity Relationship

2012
Amino acid transport in thermophiles: characterization of an arginine-binding protein from Thermotoga maritima. 3. Conformational dynamics and stability.
    Journal of photochemistry and photobiology. B, Biology, 2013, Jan-05, Volume: 118

    Topics: Arginine; Calorimetry, Differential Scanning; Guanidine; Periplasmic Binding Proteins; Protein Conformation; Protein Stability; Protein Structure, Secondary; Protein Unfolding; Thermotoga maritima

2013
Visual detection of arginine based on the unique guanidino group-induced aggregation of gold nanoparticles.
    Analytica chimica acta, 2013, Feb-18, Volume: 764

    Topics: Arginine; Citric Acid; Colorimetry; Gold; Guanidine; Hydrogen Bonding; Isoelectric Point; Metal Nanoparticles; Static Electricity

2013
Preparation of guanidinium terminus-molecularly imprinted polymers for selective recognition and solid-phase extraction (SPE) of [arginine]-microcystins.
    Analytical and bioanalytical chemistry, 2013, Volume: 405, Issue:12

    Topics: Arginine; Chromatography, Liquid; Guanidine; Microcystins; Microcystis; Molecular Imprinting; Polymers; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Water Microbiology

2013
Molecular dynamics simulation of the arginine-assisted solubilization of caffeic acid: intervention in the interaction.
    The journal of physical chemistry. B, 2013, Jun-27, Volume: 117, Issue:25

    Topics: Arginine; Caffeic Acids; Guanidine; Molecular Dynamics Simulation; Principal Component Analysis; Solubility; Thermodynamics

2013
Synthesis of guanidino sugar conjugates as GlcβArg analogs.
    Glycoconjugate journal, 2013, Volume: 30, Issue:8

    Topics: Acetamides; Arginine; Carbohydrates; Glucosides; Guanidine; Triazoles

2013
Dimeric argininamide-type neuropeptide Y receptor antagonists: chiral discrimination between Y1 and Y4 receptors.
    Bioorganic & medicinal chemistry, 2013, Nov-01, Volume: 21, Issue:21

    Topics: Arginine; Dimerization; Fura-2; Guanidine; Humans; Models, Molecular; Protein Binding; Receptors, Neuropeptide Y; Stereoisomerism; Structure-Activity Relationship; Urea

2013
Structural determinants for the strict monomethylation activity by trypanosoma brucei protein arginine methyltransferase 7.
    Structure (London, England : 1993), 2014, May-06, Volume: 22, Issue:5

    Topics: Amino Acid Sequence; Arginine; Catalytic Domain; Crystallography, X-Ray; Guanidine; Histones; Methylation; Models, Molecular; Molecular Sequence Data; Protein Multimerization; Protein-Arginine N-Methyltransferases; Protozoan Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine; Trypanosoma brucei brucei

2014
Effect of side chain length on intrahelical interactions between carboxylate- and guanidinium-containing amino acids.
    Amino acids, 2014, Volume: 46, Issue:8

    Topics: 2-Aminoadipic Acid; Alanine; Amino Acid Sequence; Amino Acids; Arginine; Aspartic Acid; Carboxylic Acids; Circular Dichroism; Glutamic Acid; Guanidine; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Molecular Conformation; Peptides; Protein Structure, Secondary; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Static Electricity; Thermodynamics

2014
Competitive formation of b(2) and c(2)-H2O ions from b(3) ions containing Asp residue during tandem mass spectrometry: the influence of neighboring Arg.
    Amino acids, 2014, Volume: 46, Issue:8

    Topics: Arginine; Aspartic Acid; Glutamic Acid; Guanidine; Ions; Phenylalanine; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Water

2014
Liposomes physically coated with peptides: preparation and characterization.
    Langmuir : the ACS journal of surfaces and colloids, 2014, Jun-03, Volume: 30, Issue:21

    Topics: Amino Acid Sequence; Arginine; Cell Membrane; DNA; Drug Delivery Systems; Fluoresceins; Guanidine; Hydrogen-Ion Concentration; Light; Lipid Bilayers; Liposomes; Microscopy, Electron, Transmission; Molecular Sequence Data; Peptides; Salts; Scattering, Radiation; Static Electricity; Temperature; Water

2014
A model study for tethering of (bio)active molecules to biomaterial surfaces through arginine.
    Organic & biomolecular chemistry, 2014, Jun-28, Volume: 12, Issue:24

    Topics: Animals; Arginine; Biocompatible Materials; Collagen; Guanidine; Horses; Ketones; Lactose; Pyruvaldehyde; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Surface Properties

2014
Oxidative refolding of rPA in l-ArgHCl and in ionic liquids: A correlation between hydrophobicity, salt effects, and refolding yield.
    Biopolymers, 2014, Volume: 101, Issue:11

    Topics: Amino Acids; Arginine; Guanidine; Hydrophobic and Hydrophilic Interactions; Imidazoles; Ionic Liquids; Organophosphates; Oxidation-Reduction; Plasminogen Activators; Protein Refolding; Recombinant Proteins; Sodium Chloride; Solubility; Solvents; Thermodynamics

2014
Novel lysosome targeted molecular transporter built on a guanidinium-poly-(propylene imine) hybrid dendron for efficient delivery of doxorubicin into cancer cells.
    Chemical communications (Cambridge, England), 2015, Feb-11, Volume: 51, Issue:12

    Topics: Antibiotics, Antineoplastic; Apoptosis; Arginine; Cathepsin B; Dendrimers; Doxorubicin; Drug Carriers; Guanidine; HeLa Cells; Humans; Lysosomes; Peptides; Polypropylenes

2015
Role of arginine in mediating protein-carbon nanotube interactions.
    Langmuir : the ACS journal of surfaces and colloids, 2015, Feb-10, Volume: 31, Issue:5

    Topics: Arginine; Guanidine; Hydrophobic and Hydrophilic Interactions; Molecular Dynamics Simulation; Muramidase; Nanotubes, Carbon; Protein Conformation; Surface Properties; Water

2015
Modulation of hydrophobic interactions by proximally immobilized ions.
    Nature, 2015, Jan-15, Volume: 517, Issue:7534

    Topics: Ammonium Compounds; Arginine; Buffers; Cations; Colloids; Ethanolamines; Guanidine; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Lysine; Methanol; Microscopy, Atomic Force; Peptides; Protons; Reproducibility of Results; Surface Properties

2015
Interaction of arginine, lysine, and guanidine with surface residues of lysozyme: implication to protein stability.
    Journal of biomolecular structure & dynamics, 2016, Volume: 34, Issue:1

    Topics: Arginine; Guanidine; Hydrogen Bonding; Lysine; Molecular Dynamics Simulation; Muramidase; Protein Stability; Proteins; Surface Properties; Water

2016
Controlling protein stability: Mechanisms revealed using formulations of arginine, glycine and guanidinium HCl with three globular proteins.
    International journal of pharmaceutics, 2015, Volume: 486, Issue:1-2

    Topics: Arginine; Calorimetry, Differential Scanning; Glycine; Guanidine; Muramidase; Myoglobin; Protein Stability; Serum Albumin, Bovine; Temperature

2015
Enzymatic production of l-citrulline by hydrolysis of the guanidinium group of l-arginine with recombinant arginine deiminase.
    Journal of biotechnology, 2015, Aug-20, Volume: 208

    Topics: Arginine; Bacterial Proteins; Citrulline; Escherichia coli; Guanidine; Hydrolases; Lactococcus lactis; Recombinant Proteins

2015
Like-Charge Guanidinium Pairing between Ligand and Receptor: An Unusual Interaction for Drug Discovery and Design?
    The journal of physical chemistry. B, 2015, Sep-10, Volume: 119, Issue:36

    Topics: Arginine; Databases, Protein; Drug Design; Electrons; Guanidine; Ligands; Models, Molecular; Protein Conformation; Proteins; Thermodynamics

2015
Improved Gas Chromatographic Determination of Guanidino Compounds Using Isovaleroylacetone and Ethyl Chloroformate as Derivatizing Reagents.
    Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2016, Volume: 32, Issue:2

    Topics: Acetone; Arginine; Boric Acids; Butyrates; Butyric Acid; Calibration; Chromatography, Gas; Creatinine; Formic Acid Esters; Glycine; Guanidine; Guanidines; Healthy Volunteers; Humans; Hydrogen-Ion Concentration; Ketones; Limit of Detection; Methylguanidine; Propionates; Reference Values; Reproducibility of Results; Succinates; Uremia

2016
Arginine side chain interactions and the role of arginine as a gating charge carrier in voltage sensitive ion channels.
    Scientific reports, 2016, Feb-22, Volume: 6

    Topics: Amino Acid Sequence; Animals; Arginine; Databases, Protein; ERG1 Potassium Channel; Guanidine; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Ion Channel Gating; Lysine; Molecular Dynamics Simulation; Protein Isoforms; Static Electricity; Structural Homology, Protein; Structure-Activity Relationship; Water

2016
Novel prodrugs with a spontaneous cleavable guanidine moiety.
    Bioorganic & medicinal chemistry letters, 2016, Apr-01, Volume: 26, Issue:7

    Topics: Anti-Infective Agents; Anticonvulsants; Arginine; Drug Stability; Guanidine; Phenytoin; Prodrugs; Solubility; Sulfathiazole; Sulfathiazoles; Water

2016
Effect of counter ions of arginine as an additive for the solubilization of protein and aromatic compounds.
    International journal of biological macromolecules, 2016, Volume: 91

    Topics: Amino Acids, Aromatic; Arginine; Guanidine; Muramidase; Propyl Gallate; Protein Refolding; Solubility

2016
Geometry of guanidinium groups in arginines.
    Protein science : a publication of the Protein Society, 2016, Volume: 25, Issue:9

    Topics: Arginine; Guanidine

2016
Arginine as a protein stabilizer and destabilizer in liquid formulations.
    International journal of pharmaceutics, 2016, Nov-20, Volume: 513, Issue:1-2

    Topics: Arginine; Chemistry, Pharmaceutical; Creatinine; Drug Stability; Drug Storage; Etanercept; Guanidine; Hot Temperature; Hydrogen Peroxide; Hydrogen-Ion Concentration; Protein Denaturation; Transition Temperature

2016
Arginine-Substituted Phthalocyanine with Concentration-Driven Self-Disaggregation Performance: Synthesis, Properties and Mechanistic Study.
    Chemistry, an Asian journal, 2016, Nov-07, Volume: 11, Issue:21

    Topics: Arginine; Catalysis; Esters; Guanidine; Hydrogen Bonding; Hydrolysis; Indoles; Isoindoles; Organometallic Compounds; Solvents; Spectrophotometry, Ultraviolet; Zinc Compounds

2016
Efficient Mini-Transporter for Cytosolic Protein Delivery.
    ACS applied materials & interfaces, 2016, Oct-05, Volume: 8, Issue:39

    Topics: Arginine; Cell-Penetrating Peptides; Cytosol; Drug Delivery Systems; Guanidine; Membrane Transport Proteins

2016
Interaction of free arginine and guanidine with glucose under thermal processing conditions and formation of Amadori-derived imidazolones.
    Food chemistry, 2017, Apr-01, Volume: 220

    Topics: Arginine; Glucose; Guanidine; Imidazoles; Pyruvaldehyde; Tandem Mass Spectrometry

2017
Effect of guanidine and arginine on protein-ligand interactions in multimodal cation-exchange chromatography.
    Biotechnology progress, 2017, Volume: 33, Issue:2

    Topics: Arginine; Binding Sites; Cation Exchange Resins; Chromatography, Ion Exchange; Guanidine; Ligands; Models, Chemical; Molecular Dynamics Simulation; Protein Binding; Protein Interaction Mapping; Proteins

2017
Guanidinium Group Remains Protonated in a Strongly Basic Arginine Solution.
    Chemphyschem : a European journal of chemical physics and physical chemistry, 2017, Jun-20, Volume: 18, Issue:12

    Topics: Arginine; Guanidine; Hydrogen-Ion Concentration; Photoelectron Spectroscopy; Protons; Solutions

2017
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    Journal of biomolecular NMR, 2017, Volume: 69, Issue:3

    Topics: Arginine; Carbon Isotopes; Guanidine; Muramidase; Mutation, Missense; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments

2017
Guanidinium/ammonium competition and proton transfer in the interaction of the amino acid arginine with the tetracarboxylic 18-crown-6 ionophore.
    Physical chemistry chemical physics : PCCP, 2018, Feb-07, Volume: 20, Issue:6

    Topics: Ammonium Compounds; Arginine; Crown Ethers; Guanidine; Protons; Quantum Theory; Spectrophotometry, Infrared

2018
Protein Aggregation and Performance Optimization Based on Microconformational Changes of Aromatic Hydrophobic Regions.
    Molecular pharmaceutics, 2018, 06-04, Volume: 15, Issue:6

    Topics: Arginine; Chemistry, Pharmaceutical; Guanidine; Hydrophobic and Hydrophilic Interactions; Molecular Dynamics Simulation; Protein Aggregates; Protein Conformation; Proteins; Solubility; Surface Properties; Tryptophan

2018
Purification and characterization of arginine deiminase from Pseudomonas putida: Structural insights of the differential affinities of l-arginine analogues.
    Journal of bioscience and bioengineering, 2019, Volume: 127, Issue:2

    Topics: Arginine; Catalytic Domain; Guanidine; Hydrolases; Models, Molecular; Molecular Docking Simulation; Protein Binding; Protein Structure, Quaternary; Protein Structure, Secondary; Pseudomonas aeruginosa; Pseudomonas putida; Substrate Specificity

2019
Design, Synthesis, Molecular Dynamics Simulation, and Functional Evaluation of a Novel Series of 26RFa Peptide Analogues Containing a Mono- or Polyalkyl Guanidino Arginine Derivative.
    Journal of medicinal chemistry, 2018, 11-21, Volume: 61, Issue:22

    Topics: Alkylation; Amides; Animals; Arginine; Chemistry Techniques, Synthetic; CHO Cells; Cricetulus; Drug Design; Guanidine; Molecular Dynamics Simulation; Oligopeptides; Protein Conformation

2018
Tuning Stacking Interactions between Asp-Arg Salt Bridges and Heterocyclic Drug Fragments.
    Journal of chemical information and modeling, 2019, 01-28, Volume: 59, Issue:1

    Topics: Arginine; Aspartic Acid; Guanidine; Heterocyclic Compounds; Models, Molecular; Protein Binding; Proteins; Static Electricity; Thermodynamics

2019
Guanidinylated chitosan inspired by arginine-rich cell-penetrating peptides.
    International journal of biological macromolecules, 2019, Mar-15, Volume: 125

    Topics: Arginine; Cell-Penetrating Peptides; Chitosan; Drug Carriers; Drug Delivery Systems; Guanidine; Serum Albumin, Bovine

2019
An N-nitrosating metalloenzyme constructs the pharmacophore of streptozotocin.
    Nature, 2019, Volume: 566, Issue:7742

    Topics: Arginine; Catalytic Domain; Coenzymes; Crystallography, X-Ray; Guanidine; Iron; Metalloproteins; Models, Molecular; Multigene Family; Nitrosourea Compounds; Streptomyces; Streptozocin

2019
The binding affinity of uncharged aromatic solutes for negatively charged resins is enhanced by cations via cation-π interactions: The case of sodium ion and arginine.
    Journal of chromatography. A, 2019, Jun-21, Volume: 1595

    Topics: Arginine; Cation Exchange Resins; Cations; Chromatography, Ion Exchange; Guanidine; Ligands; Molecular Dynamics Simulation; Proteins; Sodium; Sodium Chloride; Solutions

2019
Structural and Functional Insights into Host Death Domains Inactivation by the Bacterial Arginine GlcNAcyltransferase Effector.
    Molecular cell, 2019, 06-06, Volume: 74, Issue:5

    Topics: Animals; Apoptosis; Arginine; Coenzyme A Ligases; Crystallography, X-Ray; Death Domain; Enteropathogenic Escherichia coli; Escherichia coli Proteins; Guanidine; Host-Pathogen Interactions; Humans; Manganese; Mice; Mutagenesis; Protein Conformation; TNF Receptor-Associated Death Domain Protein; Virulence Factors

2019
Insights into the Recognition of Phosphate Groups by Peptidic Arginine from Action Spectroscopy and Quantum Chemical Computations.
    The journal of physical chemistry. B, 2019, 09-05, Volume: 123, Issue:35

    Topics: Arginine; Guanidine; Peptides; Phosphates; Quantum Theory; Spectrophotometry, Infrared

2019
Arginine π-stacking drives binding to fibrils of the Alzheimer protein Tau.
    Nature communications, 2020, Jan-29, Volume: 11, Issue:1

    Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid; Animals; Arginine; Disease Progression; Guanidine; HSP90 Heat-Shock Proteins; Humans; Mass Spectrometry; Molecular Chaperones; Protein Aggregates; Protein Binding; Protein Domains; Protein Folding; Proteome; Rats; Sequence Analysis, Protein; tau Proteins

2020
Gas-Phase Fragmentation of ADP-Ribosylated Peptides: Arginine-Specific Side-Chain Losses and Their Implication in Database Searches.
    Journal of the American Society for Mass Spectrometry, 2021, Jan-06, Volume: 32, Issue:1

    Topics: Adenosine Diphosphate Ribose; ADP-Ribosylation; Arginine; Databases, Protein; Gases; Guanidine; Mass Spectrometry; Peptides; Protein Processing, Post-Translational; Serine

2021
Insight into the protein salting-in mechanism of arginine, magnesium chloride and ethylene glycol: Solvent interaction with aromatic solutes.
    International journal of biological macromolecules, 2021, Oct-01, Volume: 188

    Topics: Arginine; Benzyl Alcohols; Diketopiperazines; Ethylene Glycol; Gallic Acid; Guanidine; Magnesium Chloride; Proteins; Salts; Solubility; Solvents; Thermodynamics; Water

2021
Role of the Guanidinium Groups in Ligand-Receptor Binding of Arginine-Containing Short Peptides to the Slow Sodium Channel: Quantitative Approach to Drug Design of Peptide Analgesics.
    International journal of molecular sciences, 2022, Sep-13, Volume: 23, Issue:18

    Topics: Analgesics; Arginine; Drug Design; Guanidine; Ligands; Peptides; Sodium Channels

2022
Biochemical characterization of a cyanobactin arginine-
    Chemical communications (Cambridge, England), 2022, Oct-27, Volume: 58, Issue:86

    Topics: Arginine; Biosynthetic Pathways; Dimethylallyltranstransferase; Guanidine; Homoarginine; Peptides, Cyclic

2022
Insights into the binding of arginine to adenosine phosphate from mimetic complexes.
    Physical chemistry chemical physics : PCCP, 2022, Nov-18, Volume: 24, Issue:44

    Topics: Adenine; Adenine Nucleotides; Adenosine Monophosphate; Arginine; Guanidine; Ions; Phosphates; Sodium

2022
Interaction of guanidinium and ammonium cations with phosphatidylcholine and phosphatidylserine lipid bilayers - Calorimetric, spectroscopic and molecular dynamics simulations study.
    Biochimica et biophysica acta. Biomembranes, 2023, Volume: 1865, Issue:4

    Topics: Arginine; Calorimetry; Cations; Cell-Penetrating Peptides; Guanidine; Lecithins; Lipid Bilayers; Lysine; Molecular Dynamics Simulation; Phosphatidylserines; Spectrum Analysis

2023
Synthesis and evaluation of a deltic guanidinium analogue of a cyclic RGD peptide.
    Organic & biomolecular chemistry, 2023, 03-01, Volume: 21, Issue:9

    Topics: Arginine; Guanidine; Oligopeptides; Peptides; Tissue Distribution

2023
Rapid Mitochondria Targeting by Arginine-Terminated, Sub-10 nm Nanoprobe via Direct Cell Membrane Penetration.
    ACS applied bio materials, 2023, 06-19, Volume: 6, Issue:6

    Topics: Arginine; Cell Membrane; Drug Carriers; Drug Delivery Systems; Guanidine; Mitochondria

2023