arginine has been researched along with fibrinogen in 173 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 75 (43.35) | 18.7374 |
| 1990's | 32 (18.50) | 18.2507 |
| 2000's | 38 (21.97) | 29.6817 |
| 2010's | 21 (12.14) | 24.3611 |
| 2020's | 7 (4.05) | 2.80 |
| Authors | Studies |
|---|---|
| Behar, C; Droulle, C; Ledoyen, MP; Leroux, B; Mascre, W; Potron, G | 1 |
| Odeberg, H; Olsson, I; Venge, P | 1 |
| Jeljaszewicz, J; Wagrzynowicz, Z; Zajdel, M | 1 |
| Kang, EP; Triantaphyllopoulos, DC | 1 |
| Hijikata, A; Kikumoto, R; Kinjo, K; Okamoto, S; Okubo, K | 1 |
| Hijikate, A; Ikezawa, K; Kikimoto, R; Okamoto, S; Tamao, Y; Tonomura, S | 1 |
| Gorman, JJ | 1 |
| Grinenko, TV; Kudinov, SA; Skomorovskaia, EV; Zolotareva, EN | 1 |
| Coyne, CP; DeBowes, RM; Smith, JE | 1 |
| Hanashiro, K; Kinjoh, K; Kosugi, T; Nakamura, M; Saitoh, S | 1 |
| Atagi, S; Fukuta, K; Ogura, T; Sone, S | 1 |
| Butler, KD; Crook, P; May, GR; Page, CP; Paul, W | 1 |
| Furukawa, K; Iwanaga, S; Miyata, T; Saito, H; Takamatsu, J | 1 |
| Hirata, H; Matsuda, M; Miyata, T; Shimonishi, Y; Takao, T; Takeda, Y; Terukina, S | 1 |
| Matsuda, M; Onohara, S; Terukina, S; Yamazumi, K | 1 |
| Houghten, RA; Ruggeri, ZM; Russell, SR; Zimmerman, TS | 1 |
| Farbiszewski, R; Sokól, A | 1 |
| Lebret, M; Rendu, F | 1 |
| Henriksen, RA; Mann, KG | 1 |
| Matsuda, M; Moroi, M; Ota, K; Yoshida, N | 1 |
| Barbui, T; Beck, EA; Berrettini, M; Furlan, M; Henschen, A; Hilgard, P; Kaudewitz, H; Nenci, GG; Reber, P | 1 |
| Inomoto, T; Iwanaga, S; Kawauchi, S; Miyata, T; Morita, T; Shirakami, A | 1 |
| Kaminski, M; McDonagh, J | 1 |
| Hara, H; Kikumoto, R; Okamoto, S; Tamao, Y | 1 |
| Alving, BM; Henschen, AH | 1 |
| Iwanaga, S; Kasamatsu, A; Matsuda, M; Miyata, T; Murakami, T; Takeda, Y; Terukina, S | 1 |
| Carr, ME; Qureshi, GD | 1 |
| Bell, WR; Ebert, RF; Schreiler, WE | 1 |
| Etoh, T; Higuchi, M; Ikezawa, K; Kakishita, E; Kanamaru, A; Kunitomi, O; Nagai, K; Nakajima, T; Nishida, Y | 1 |
| Horie, N; Nagamatsu, Y; Okamoto, U; Sasaki, K; Yamamoto, J | 1 |
| Abildgaard, U | 1 |
| Bergström, K; Blombäck, M | 1 |
| Bell, CE; Birndorf, NI; Colman, RW; Lopas, H; Robboy, SJ | 1 |
| Cartwright, T | 1 |
| Iwanaga, S; Wallén, P | 1 |
| Triantaphyllopoulos, DC; Triantaphyllopoulos, E | 1 |
| Ambrus, CM; Ambrus, JL; Lassman, HB; Mink, IB | 1 |
| Doolittle, RF; Weinstein, MJ | 1 |
| Berthoud, S; Bouvier, CA | 1 |
| Harpel, PC; Mosesson, MW | 1 |
| Landmann, H | 1 |
| Geokas, MC; Rinderknecht, H | 1 |
| Danan, JL; Mester, L | 1 |
| Brain, MC; Hatton, MW; Pineo, GF; Regoeczi, E | 1 |
| Farbiszewski, R; Glowiński, S; Worowski, K | 1 |
| Blombäck, B; Hogg, DH | 1 |
| Phillips, HM; York, JL | 1 |
| Ho, J; Jeejeebhoy, KN; Painter, RH | 1 |
| Brecher, AS; Burkholder, DE; Burkholder, JS; Howe, WF | 1 |
| Beamont, KP; Phillips, GO; Power, DM | 1 |
| Andersson, L | 1 |
| Farbiszewski, R; Glowinski, S; Rzeczycki, W; Worowski, K | 1 |
| Harrison, JH; Lundblad, RL; Mann, KG | 1 |
| Ardlie, NG; Han, P | 1 |
| Koj, A; McFarlane, AS | 1 |
| Hill, RD | 1 |
| Exner, T; Koppel, JL | 1 |
| Fass, DN; Heldebrant, CM; Mann, KG | 1 |
| Andreatta, RH; Liem, RK; Scheraga, HA | 1 |
| Basford, JM; Collins, JP; Jones, JG | 1 |
| Berlin, NI; Houston, D; Waldmann, TA; Weissman, SM; Wochner, RD | 1 |
| Hata, S; Okamoto, S; Oshiba, S | 1 |
| Bruce-Robertson, A; Foley, M; Jeejeebhoy, KN; Sodtke, U | 1 |
| Karitzky, D; Künzer, W; Müller, H; Witt, I | 1 |
| Chappelle, MS; Hakim, AA | 1 |
| Brüggener, E; Hauptmann, J; Müller, H | 1 |
| Hoffmann, J; Markwardt, F; Nowak, G | 1 |
| Beck, EA; Furlan, M; Rupp, C; Sievi, R | 1 |
| Yamada, K | 1 |
| Deutsch, E; Henschen, A; Kehl, M | 1 |
| Henriksen, RA; Mann, KG; Nesheim, ME; Owen, WG | 1 |
| Griffin, MM; Steven, FS | 1 |
| Higgins, DL; Shafer, JA | 1 |
| Martinelli, RA; Scheraga, HA | 1 |
| Finiasz, MR; Lazzari, MA; Notrica, JA; Schattner, MA | 1 |
| Gryglewski, RJ; Korbut, R; Vane, JR; Warner, TD | 1 |
| Born, GV; Cardona-Sanclemente, LE | 1 |
| Rółkowski, R; Skrzydlewski, Z; Worowski, K | 1 |
| Benson, MD; Correa, R; Liepnieks, J; Uemichi, T; Wheeler, G | 1 |
| Ferrara, JD; Padmanabhan, K; Padmanabhan, KP; Sadler, JE; Tulinsky, A | 1 |
| Hijikata-Okunomiya, A; Okamoto, S | 1 |
| Caen, JP; DiOrio, JP; Mosesson, MW; Siebenlist, KR; Soria, C; Soria, J | 1 |
| Bezeaud, A; Bouton, MC; Guillin, MC; Jandrot-Perrus, M | 1 |
| Côté, HF; MacGillivray, RT; Nesheim, ME; Stevens, WK | 1 |
| Imaizumi, T; Kohno, K; Matsuoka, H; Morimatsu, M; Nakashima, A; Nishida, H; Nomura, G; Yasukawa, H | 1 |
| Beck, EA; Furlan, M; Jungo, M; Lämmle, B; Steinmann, C | 1 |
| Akiguchi, I; Kaji, R; Kanda, M; Murase, N; Satoi, H | 1 |
| Coulombe, R; Cygler, M; Féthière, J; Konishi, Y; Tsuda, Y | 1 |
| Chen, CT; Chen, H; Jen, CJ | 1 |
| Hata, T; Kawabata, A | 1 |
| Evanson, OA; Weiss, DJ; Wells, RE | 1 |
| Eguchi, Y; Hanashiro, K; Kinjoh, K; Kosugi, T; Nakamura, M; Sunagawa, M; Tokeshi, Y | 1 |
| Altorjay, I; Harsfalvi, J; Palatka, K; Posán, E; Udvardy, M | 1 |
| Arfsten, AE; Bastian, JA; Denney, ML; Harms, CS; Jakubowski, JA; McCowan, JR; Morin, JM; Rose, JW; Sall, DJ; Scarborough, RM; Smyth, MS; Um, SL; Utterback, BG; Vasileff, RT; Wikel, JH; Wyss, VL | 1 |
| de Mazancourt, P; Denninger, MH; Detruit, H; Giudicelli, Y; Guillon, L; Mathonnet, F; Van Amerongen, G | 1 |
| Brennan, SO; George, PM; Hammonds, B; Spearing, R | 1 |
| Isaacs, SN; Lambris, JD; Sahu, A; Soulika, AM | 1 |
| Akiguchi, I; Kimura, J; Kinoshita, M; Nishimura, M; Osaki, A; Tomimoto, H; Wakita, H | 1 |
| Kawata, Y; Madoiwa, S; Matsuda, M; Mimuro, J; Muramatsu, S; Niwa, K; Nose, K; Sakata, Y; Sugimoto, T; Sugo, T; Takano, H | 1 |
| Hayashida, N; Kitano, K; Lord, ST; Okazaki, M; Okumura, N; Shimosaka, M; Terasawa, F | 1 |
| Laffan, M; Manning, R; Mille-Baker, B; Mumford, A; Vakalopoulou, S | 1 |
| Fisher, MJ; Giese, U; Harms, CS; Jakubowski, JA; Kinnick, MD; Lindstrom, TD; McCowan, JR; Mest, HJ; Morin, JM; Mullaney, JT; Paal, M; Rapp, A; Rühter, G; Ruterbories, KJ; Sall, DJ; Scarborough, RM; Schotten, T; Stenzel, W; Towner, RD; Um, SL; Utterback, BG; Wyss, VL | 1 |
| Ataullakhanov, FI; Krasotkina, YV; Sinauridze, EI | 1 |
| Imamura, T; Potempa, J; Travis, J | 1 |
| Banbula, A; Imamura, T; Pereira, PJ; Potempa, J; Travis, J | 1 |
| Connell, ME; Li, YT; Liang, JF; Yang, VC | 1 |
| Kinjoh, K; Kosugi, T; Nakamura, M; Zeng, G | 1 |
| Bruhn, HD; Gram, J; Seydewitz, HH; Witt, I | 1 |
| Bellini, MA; Boschi, L; Forconi, S; Guerrini, M; Pallassini, A; Postorino, G; Richichi, MG; Trabalzini, L; Turchetti, V | 1 |
| Brennan, SO; Fellowes, AP; George, PM; Maghzal, GJ; Spearing, R | 1 |
| Holman, WL; Kieta, DR; McCammon, AT; Nielsen, VG | 1 |
| TRIANTAPHYLLOPOULOS, DC | 1 |
| DRUMMOND, MC; TAGER, M | 1 |
| PAGE, IH; SHAINOFF, JR | 1 |
| MCFARLANE, AS | 1 |
| ABILDGAARD, U; GODAL, HC | 1 |
| Ally, N; Le Bonniec, BF; Pike, RN; Potempa, J; Sieprawska-Lupa, M; Travis, J; Whisstock, JC | 1 |
| Akhavan, S; Altomare, C; Carotti, A; De Cristofaro, R; Mannucci, PM; Peyvandi, F | 1 |
| Berg, C; Herrmann, BL; Mann, K; Nowak, T; Renzing-Koehler, K; Saller, B; Vogel, E | 1 |
| Betts, L; Bolliger-Stucki, B; Gorkun, OV; Kostelansky, MS; Lord, ST | 1 |
| Hirota-Kawadobora, M; Ishii, K; Ishikawa, S; Okumura, N; Terasawa, F; Tozuka, M | 1 |
| Adachi, Y; Hida, S; Miura, NN; Ohno, N | 1 |
| Fernández, JA; Griffin, JH; Mesters, RM; Yegneswaran, S | 1 |
| Ahrén, B; Björk, J; Cavallin-Ståhl, E; Erfurth, EM; Garwicz, S; Link, K; Moëll, C; Thilén, U | 1 |
| Furukawa, H; Kasuya, A; Kawaida, R; Kubota, K; Nakayama-Hamada, M; Ohsaka, M; Ono, M; Suzuki, A; Takazawa, T; Yamada, R; Yamamoto, K | 1 |
| Dai, J; Ding, Q; Fang, Y; Qi, H; Wang, H; Wang, W; Wang, X; Wu, W; Xie, S; Zhou, R | 1 |
| Asselta, R; Braidotti, P; Coggi, G; Duga, S; Maggioni, M; Malcovati, M; Pellegrini, C; Santagostino, E; Tenchini, ML | 1 |
| Kawano, HA; Nakajima, T; Suzuki, J; Tomaru, T; Tsujiuchi, Y; Uchida, Y | 1 |
| Moriyama, A; Ogiwara, K; Rajapakse, S; Takahashi, T; Takano, N | 1 |
| Bernet, J; Mullick, J; Sahu, A; Singh, AK | 1 |
| Malé, PJ; Neerman-Arbez, M; Rougemont, AL; Rubbia-Brandt, L; Spahr, L | 1 |
| Brennan, SO; Dear, A; Dolan, G; Hill, MB; Nejim, T; Strong, J | 1 |
| de Mazancourt, P; de Raucourt, E; Fischer, AM; Meyer, G | 1 |
| Ambrose, J; Bernaski, E; Coppola, J; El-Khally, Z; Kurian, D; Mandadi, V; Morlote, M; Pinassi, E; Staniloae, C | 1 |
| Kirklin, JK; Nielsen, VG | 1 |
| Renz, H; Stief, TW; Wieczerzak, A | 1 |
| Aguiar, AS; Bourguignon, SC; Di Cera, E; Garvey, LC; Giovanni-De-Simone, S; Guedes, HL; Silva-Junior, FP | 1 |
| Doolittle, RF; Pandi, L | 1 |
| Brunini, TM; da Silva, MN; de Meirelles, LR; Mann, GE; Mendes, MA; Mendes-Ribeiro, AC; Santoro, MM | 1 |
| Furukawa, H; Nakayama-Hamada, M; Suzuki, A; Yamada, R; Yamamoto, K | 1 |
| Bush, LA; Di Cera, E; Gruber, A; Hanson, SR; Szlam, F; Tanaka, KA | 1 |
| Adan-Kubo, J; Hagiwara, K; Hattori, S; Ikuta, K; Nishida, A; Nishigaki, H; Tanaka, H; Tanaka, Y; Tsujikawa, M; Urayama, T; Yamamoto, I; Yamamoto, S; Yoshikawa, M; Yunoki, M | 1 |
| Gnyp, W; Grela, W; Koszowski, B; Sobczak, A; Szołtysek-Bołdys, I; Zielińska-Danch, W | 1 |
| Altenburg, C; Beil, U; Benndorf, R; Böger, RH; Glos, S; Maas, R; Petruschka, D; Schulze, F; Schwedhelm, E | 1 |
| Ishibashi, N; Ishii, H; Kurosawa, H; Okamura, T; Shin'oka, T | 1 |
| Blank, D; Chari, A; Dettwiler, S; Fischer, U; Keller, W; Martin, G; Neuenkirchen, N; Ostareck-Lederer, A; Rüegsegger, U | 1 |
| Brennan, SO; Davis, RL | 1 |
| Brunini, TM; Lugon, JR; Martins, MA; Mendes-Ribeiro, AC; Moss, MB; Pereira, NR; Santos, SF; Siqueira, MA | 1 |
| Armstrong, VW; Helfmann, J; Hintze, E; Konstantinides, S; Koziolek, MJ; Lange, K; Mueller, GA; Rossenbach, J; Schmitto, JD | 1 |
| Aral, H; Gurel, MS; Guvenen, G; Inal, BB; Oner, E; Oner, FA; Turan, E; Usta, M; Yurdakul, S | 1 |
| Brunini, TM; Cascarelli, PG; de Meirelles, LR; Matsuura, C; Mendes-Ribeiro, AC; Pereira, NR; Resende, Ade C; Salgado, A | 1 |
| Andronati, SA; Grygorash, RY; Kabanov, VM; Kabanova, TA; Khristova, TM; Krysko, AA; Krysko, OL; Kuz'min, VE; Polishchuk, PG; Samoylenko, GV; Varnek, AA | 1 |
| Doolittle, RF; Surgenor, DM | 1 |
| Abdel Aziz, MH; Desai, UR; Farrell, DH; Kim, JY; Liang, A; Mosier, PD; Sidhu, PS; Zhou, Q | 1 |
| Cha, S; Choi, M; Kim, HJ; Lee, EY; Song, JS | 1 |
| Grupi, A; Minton, AP | 1 |
| Fan, Q; Geng, P; Li, W; Li, Y; Lin, L; Song, L; Wang, N | 1 |
| Abdul-Ghani, M; Cakirca, M; Camli, AA; Cikrikcioglu, MA; Erkoc, R; Hursitoglu, M; Kanat, M; Karatoprak, C; Kiskac, M; Soysal, P; Zorlu, M | 1 |
| Cervera, A; Chamorro, Á; de la Rosa, X; Durduran, T; Justicia, C; Kristoffersen, AK; Planas, AM; Valdés, CP; Varma, HM | 1 |
| Akalin, A; Arabul, M; Celik, M; Cerrah, S | 1 |
| Badalamenti, S; Clerici, M; Colombo, G; Dalle-Donne, I; Giustarini, D; Milzani, A; Portinaro, N; Rossi, R | 1 |
| Ariëns, RA; Bridge, KI; Evans, HL; Johnson, A; Macrae, FL; Scott, DJ | 1 |
| Abou-Fard, GM; Shafik, NM | 1 |
| Fredenburgh, JC; Leslie, BA; Stafford, AR; Weitz, JI; Yeh, CH | 1 |
| Fan, Q; Yang, J; Zhang, L; Zhang, Z; Zheng, X | 1 |
| Ikeda, K; Kobayashi, H; Okamoto, K; Otsubo, T; Seike, S; Takahashi, E; Teraoka, F; Tsuge, H; Yamanaka, H; Yoshida, T | 1 |
| Ahmad, S; Alatar, AA; Faisal, M; Rehman, S | 1 |
| Choe, CU; Jensen, M; Müller, C; Schwedhelm, E; Zeller, T | 1 |
| Fan, Q; Zhang, L; Zhang, Z | 1 |
| Banerjee, N; Chakraborty, T; Chatterjee, S; Rai, P; Sau, S; Seal, S; Sinha, D | 1 |
| Arnoux, F; Auger, I; Hemon, MF; Lambert, NC; Roudier, J | 1 |
| Chen, R; Guo, Y; Huang, Y; Jiang, J; Li, Y; Ren, J; Zhao, Q; Zhou, J | 1 |
| Bahls, M; Böger, RH; Dörr, M; Friedrich, N; Ittermann, T; Schwedhelm, E; Winkler, MS | 1 |
2 review(s) available for arginine and fibrinogen
| Article | Year |
|---|---|
Thrombin inhibiting action of heparin.
Topics: Antithrombins; Arginine; Blood Coagulation Disorders; Fibrinogen; Half-Life; Heparin; Platelet Adhesiveness; Protamines; Thrombin; Tosyl Compounds | 1972 |
Thrombin specificity.
Topics: Amino Acid Sequence; Animals; Arginine; Autoantibodies; Binding Sites; Blood Coagulation Factors; Fibrinogen; Humans; Isoantibodies; Lysine; Macromolecular Substances; Molecular Sequence Data; Point Mutation; Protease Inhibitors; Protein Binding; Receptors, Thrombin; Substrate Specificity; Thrombin | 1995 |
5 trial(s) available for arginine and fibrinogen
| Article | Year |
|---|---|
Effects of a combination of recombinant human growth hormone with metformin on glucose metabolism and body composition in patients with metabolic syndrome.
Topics: Aged; Arginine; Blood Glucose; Blood Pressure; Body Composition; Body Constitution; Body Weight; Diabetes Mellitus, Type 2; Double-Blind Method; Fibrinogen; Glucose Tolerance Test; Glycated Hemoglobin; Growth Hormone-Releasing Hormone; Human Growth Hormone; Humans; Insulin Resistance; Insulin-Like Growth Factor I; Lipids; Male; Metabolic Syndrome; Metformin; Middle Aged; Obesity; Placebos; Testosterone | 2004 |
Pioglitazone improves endothelial function in non-diabetic patients with coronary artery disease.
Topics: Adult; Aged; Arginine; Blood Sedimentation; Brachial Artery; C-Reactive Protein; Cardiovascular Agents; Coronary Artery Disease; Endothelium, Vascular; Fibrinogen; Humans; Lipids; Male; Middle Aged; Pioglitazone; PPAR gamma; Prospective Studies; Thiazolidinediones | 2007 |
Inhibitory effects of endogenous L-arginine analogues on nitric oxide synthesis in platelets: role in platelet hyperaggregability in hypertension.
Topics: Arginine; Blood Platelets; C-Reactive Protein; Cyclic GMP; Female; Fibrinogen; Humans; Hypertension; Interleukin-6; Leucine; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Platelet Aggregation; Tumor Necrosis Factor-alpha | 2007 |
L-Arginine enhances the triglyceride-lowering effect of simvastatin in patients with elevated plasma triglycerides.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Arginine; Aspartate Aminotransferases; Dietary Supplements; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Female; Fibrinogen; Humans; Hypertriglyceridemia; Hypolipidemic Agents; Male; Middle Aged; Placebos; Simvastatin; Triglycerides | 2009 |
Effect of vildagliptin add-on treatment to metformin on plasma asymmetric dimethylarginine in type 2 diabetes mellitus patients.
Topics: Adamantane; Adult; Aged; Arginine; C-Reactive Protein; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Drug Combinations; Female; Fibrinogen; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Nitric Oxide; Nitriles; Pyrrolidines; Vildagliptin | 2014 |
166 other study(ies) available for arginine and fibrinogen
| Article | Year |
|---|---|
[The state of prothrombin, plasminogen and fibrinogen in the newborn infant].
Topics: Age Factors; Arginine; Benzamides; Blood Coagulation Tests; Coagulase; Fetal Blood; Fibrin; Fibrinogen; Fibrinolysin; Humans; Hydrogen-Ion Concentration; Infant, Newborn; Osmolar Concentration; Plasminogen; Prothrombin; Serum Albumin; Snake Venoms; Streptokinase; Thrombin | 1975 |
Cationic proteins of human granulocytes. IV. Esterase activity.
Topics: Arginine; Benzamides; Caseins; Esterases; Esters; Fibrinogen; Granulocytes; Humans; Hydrogen-Ion Concentration; Hydrolysis; Ions; Leukocytes; Molecular Weight; Phagocytosis; Proteins; Staphylococcus; Tosyl Compounds; Tyrosine | 1975 |
Action of staphylothrombin on bovine fibrinogen.
Topics: Amino Acids; Animals; Arginine; Cattle; Chromatography, Ion Exchange; Chromatography, Paper; Chromatography, Thin Layer; Coagulase; Dinitrofluorobenzene; Dinitrophenols; Fibrin; Fibrinogen; Hydrogen-Ion Concentration; Peptide Hydrolases; Peptides; Phenylthiohydantoin; Prothrombin; Staphylococcus; Thrombin | 1975 |
Fibrin digestion by thrombin: the significance of the arginyl and lysyl bonds.
Topics: Arginine; Blood Coagulation; Dialysis; Fibrin; Fibrinogen; Glyoxal; Humans; Lysine; Peptides; Spectrum Analysis; Thrombin | 1977 |
A novel series of synthetic thrombin-inhibitors having extremely potent and highly selective action.
Topics: Antithrombins; Arginine; Dansyl Compounds; Fibrinogen | 1975 |
Proceedings: Animal experiments of a new synthetic thrombin-inhibitor, dansyl-arginine-methyl-piperidine amide.
Topics: Animals; Arginine; Cattle; Dansyl Compounds; Fibrinogen; Piperidines; Rabbits; Thrombin | 1975 |
Inhibition of human thrombin assessed with different substrates and inhibitors. Characterization of fibrinopeptide binding interaction.
Topics: Arginine; Benzoylarginine Nitroanilide; Blood Coagulation; Fibrinogen; Fibrinopeptide A; Humans; Hydroxylamines; Imidazoles; Phenylacetates; Phenylmethylsulfonyl Fluoride; Structure-Activity Relationship; Thrombin; Tosyllysine Chloromethyl Ketone; Tyrosine | 1975 |
[Features of the interaction of Glu- and Lys-forms of plasminogen with native and partially hydrolyzed fibrin].
Topics: Aminocaproic Acid; Arginine; Chromatography, Affinity; Electrophoresis, Polyacrylamide Gel; Fibrin; Fibrinogen; Humans; Hydrolysis; Peptide Fragments; Plasminogen | 1992 |
Pharmacologic evaluation of factor XIIIa*-like enzyme activity in equine plasma as a potential therapeutic avenue for the inhibition of fibrinous tissue.
Topics: Analysis of Variance; Animals; Arginine; Cefuroxime; Densitometry; Electrophoresis, Cellulose Acetate; Fibrin; Fibrinogen; Glycine; Histamine; Horses; Hydroxylamine; Hydroxylamines; Iodoacetamide; Lysine; Phenelzine; Spectrophotometry, Ultraviolet; Transglutaminases | 1992 |
Changes of rabbit platelet function following simultaneous administration of Ticlopidine hydrochloride and Argipidine (MD-805).
Topics: Animals; Antithrombin III; Antithrombins; Arginine; Fibrinogen; Fibrinolysin; Hematocrit; Pipecolic Acids; Platelet Aggregation; Platelet Count; Rabbits; Sulfonamides; Ticlopidine | 1992 |
Inhibition by fibrin coagulation of lung cancer cell destruction by human interleukin-2-activated killer cells.
Topics: Aged; Aged, 80 and over; Antithrombins; Arginine; Blood Coagulation; Cell Death; Cytotoxicity, Immunologic; Female; Fibrin; Fibrinogen; Humans; Immunity, Cellular; Interleukin-2; Killer Cells, Lymphokine-Activated; Kinetics; Leukocytes, Mononuclear; Lung Neoplasms; Male; Middle Aged; Pipecolic Acids; Sulfonamides; Thrombin | 1992 |
The pharmacological modulation of thrombin-induced cerebral thromboembolism in the rabbit.
Topics: Animals; Anistreplase; Arginine; Blood Platelets; Diterpenes; Female; Fibrinogen; Fibrinolytic Agents; Ginkgolides; Hirudins; Injections, Intra-Arterial; Injections, Intravenous; Intracranial Embolism and Thrombosis; Lactones; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Polydeoxyribonucleotides; Rabbits; Recombinant Proteins; Thrombin | 1992 |
Fibrinogen Nagoya, a replacement of glutamine-329 by arginine in the gamma-chain that impairs the polymerization of fibrin monomer.
Topics: Amino Acid Sequence; Animals; Arginine; Fibrin Fibrinogen Degradation Products; Fibrinogen; Fibrinogens, Abnormal; Glutamine; Humans; Lampreys; Molecular Sequence Data | 1989 |
Substitution of gamma Arg-275 by Cys in an abnormal fibrinogen, "fibrinogen Osaka II". Evidence for a unique solitary cystine structure at the mutation site.
Topics: Adolescent; Aged; Amino Acid Sequence; Amino Acids; Arginine; Blood Coagulation Disorders; Calcium; Chromatography, High Pressure Liquid; Cysteine; Cystine; Egtazic Acid; Electrophoresis, Polyacrylamide Gel; Female; Fibrin; Fibrinogen; Fibrinogens, Abnormal; Fibrinolysin; Humans; Male; Molecular Sequence Data; Mutation; Peptide Fragments; Serine Endopeptidases; Thrombin Time | 1988 |
Normal plasmic cleavage of the gamma-chain variant of "fibrinogen Saga" with an Arg-275 to His substitution.
Topics: Adolescent; Amino Acid Sequence; Arginine; Calcium; Chromatography; Egtazic Acid; Female; Fibrinogen; Fibrinogens, Abnormal; Fibrinolysin; Histidine; Humans; Male; Serine Endopeptidases | 1988 |
Inhibition of platelet function with synthetic peptides designed to be high-affinity antagonists of fibrinogen binding to platelets.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Arginine; Binding, Competitive; Blood Platelets; Fibrinogen; Humans; Oligopeptides; Platelet Aggregation; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Structure-Activity Relationship; Thrombin | 1986 |
The interaction between fibrinogen and 3H-L-arginine cationic peptides derived from fibrosarcoma in the presence of thrombin.
Topics: Animals; Arginine; Fibrinogen; Fibrinolysis; Fibrosarcoma; Peptide Hydrolases; Peptides; Rats; Thrombin | 1988 |
Further characterization of wheat germ agglutinin interaction with human platelets: exposure of fibrinogen receptors.
Topics: Alprostadil; Arginine; Blood Platelets; Dose-Response Relationship, Drug; Edetic Acid; Fibrinogen; Humans; Kinetics; Platelet Aggregation; Platelet Membrane Glycoproteins; Protein Binding; Wheat Germ Agglutinins | 1986 |
Identification of the primary structural defect in the dysthrombin thrombin Quick I: substitution of cysteine for arginine-382.
Topics: Amino Acid Sequence; Arginine; Binding Sites; Cysteine; Fibrinogen; Humans; Molecular Sequence Data; Peptide Mapping; Prothrombin; Thrombin | 1988 |
An apparently higher molecular weight gamma-chain variant in a new congenital abnormal fibrinogen Tochigi characterized by the replacement of gamma arginine-275 by cysteine.
Topics: Arginine; Blood Coagulation; Cysteine; Fibrin; Fibrinogen; Humans; Male; Middle Aged; Molecular Weight; Mutation; Peptide Fragments; Polymers; Structure-Activity Relationship | 1988 |
Three abnormal fibrinogen variants with the same amino acid substitution (gamma 275 Arg----His): fibrinogens Bergamo II, Essen and Perugia.
Topics: Amino Acid Sequence; Arginine; Blood Coagulation Disorders; Child, Preschool; Female; Fibrin; Fibrinogen; Fibrinogens, Abnormal; Genetic Variation; Histidine; Humans; Middle Aged; Protein Conformation | 1986 |
Prothrombin Tokushima, a replacement of arginine-418 by tryptophan that impairs the fibrinogen clotting activity of derived thrombin Tokushima.
Topics: Amino Acid Sequence; Arginine; Chromatography, High Pressure Liquid; Fibrinogen; Heterozygote; Humans; Peptide Fragments; Peptide Mapping; Prothrombin; Thrombin; Tryptophan | 1987 |
Inhibited thrombins. Interactions with fibrinogen and fibrin.
Topics: Amino Acid Chloromethyl Ketones; Arginine; Binding Sites; Chromatography, Affinity; Dansyl Compounds; Dipeptides; Fibrin; Fibrinogen; Fluorescent Dyes; Hirudins; Phenylmethylsulfonyl Fluoride; Protein Binding; Pyridoxal Phosphate; Thrombin | 1987 |
Effect of a synthetic thrombin inhibitor MCI-9038 on experimental models of disseminated intravascular coagulation in rabbits.
Topics: Animals; Antithrombin III; Antithrombins; Arginine; Disseminated Intravascular Coagulation; Dose-Response Relationship, Drug; Fibrinogen; Heparin; Male; Partial Thromboplastin Time; Pipecolic Acids; Platelet Count; Rabbits; Sulfonamides; Thromboplastin | 1987 |
Fibrinogen giessen I: a congenital homozygously expressed dysfibrinogenemia with A alpha 16 Arg----His substitution.
Topics: Adult; Afibrinogenemia; Amino Acid Sequence; Arginine; Base Sequence; Chromatography, High Pressure Liquid; Female; Fibrinogen; Fibrinogens, Abnormal; Histidine; Homozygote; Humans | 1987 |
Fibrinogens Kawaguchi and Osaka: an amino acid substitution of A alpha arginine-16 to cysteine which forms an extra interchain disulfide bridge between the two A alpha chains.
Topics: Amino Acid Sequence; Arginine; Blood Coagulation Disorders; Cysteine; Disulfides; Fibrinogen; Fibrinogens, Abnormal; Humans; Macromolecular Substances; Molecular Sequence Data; Molecular Weight | 1987 |
The impact of delayed fibrinopeptide-A release on fibrin structure. Studies of an abnormal fibrinogen.
Topics: Arginine; Batroxobin; Blood Coagulation; Fibrin; Fibrinogen; Fibrinopeptide A; Histidine; Humans; Nephelometry and Turbidimetry; Osmolar Concentration; Thrombin | 1987 |
Fibrinogen Seattle II: congenital dysfibrinogenemia with an Arg (A alpha 16)----his substitution.
Topics: Afibrinogenemia; Amino Acids; Arginine; Chromatography, High Pressure Liquid; Fibrinogen; Fibrinogens, Abnormal; Fibrinopeptide A; Fibrinopeptide B; Histidine; Humans; Thrombin; Time Factors | 1986 |
[Effect of MD-805, a synthetic thrombin inhibitor, on disseminated intravascular coagulation developing in hematological disorders].
Topics: Adult; Aged; Arginine; Disseminated Intravascular Coagulation; Female; Fibrinogen; Hematologic Diseases; Humans; Male; Middle Aged; Partial Thromboplastin Time; Pipecolic Acids; Sulfonamides; Thrombin | 1985 |
Variation in activities of non-plasmin fibrinolytic proteinase and plasminogen-activator in the lung and spleen induced by bacterial endotoxin in rats with special reference to the effects of MD-805.
Topics: Animals; Arginine; Blood Coagulation Tests; Endopeptidases; Endotoxins; Escherichia coli; Female; Fibrinogen; Fibrinolytic Agents; Lipopolysaccharides; Lung; Pipecolic Acids; Plasminogen Activators; Platelet Count; Rats; Rats, Inbred Strains; Spleen; Sulfonamides; Thrombin | 1985 |
Determination of plasma prothrombin with a reaction rate analyzer using a synthetic substrate.
Topics: Anilides; Arginine; Benzoates; Buffers; Dicumarol; Factor IX; Factor VII; Factor X; Fibrinogen; Heparin; Humans; Methods; Nitro Compounds; Phenylalanine; Prothrombin; Thrombin; Time Factors; Valine | 1974 |
Immune hemolytic transfusion reactions in monkeys: activation of the kallikrein system.
Topics: Animals; Arginine; Blood Cell Count; Blood Platelets; Blood Transfusion; Disseminated Intravascular Coagulation; Enzyme Activation; Erythrocytes; Esterases; Factor V; Factor VIII; Factor X; Factor XII; Fibrinogen; Haplorhini; Hematocrit; Hemoglobins; Hemolysis; Hypotension; Immunoglobulin G; Isoantibodies; Kallikreins; Macaca; Thrombin | 1973 |
The plasminogen activator of vampire bat saliva.
Topics: Animals; Arginine; Azo Compounds; Benzoates; Blood Coagulation Tests; Blood Platelets; Chiroptera; Chromatography, DEAE-Cellulose; Chromatography, Gel; Collagen; Electrophoresis; Enzyme Activation; Esters; Fibrin; Fibrinogen; Fibrinolysis; Fibrinolytic Agents; Humans; Immunodiffusion; Lysine; Molecular Weight; Plasminogen; Proteins; Saliva; Tosyl Compounds | 1974 |
Differences between plasmic and tryptic digests of human S-sulfo-fibrinogen.
Topics: Arginine; Chromatography, Ion Exchange; Electrophoresis; Fibrinogen; Fibrinolysin; Humans; Lysine; Peptides; Sulfites; Trypsin | 1968 |
Fibrinogenolysis: the micromolecular derivatives.
Topics: Amino Acids; Arginine; Chemistry Techniques, Analytical; Chromatography, Ion Exchange; Fibrinogen; Fibrinolysin; Histidine; Lysine; Peptides; Picrates; Proteins; Streptokinase; Tryptophan | 1968 |
Studies on the mechanism of action of inhibitors of the fibrinolysin system.
Topics: Aminocaproates; Animals; Antifibrinolytic Agents; Aprotinin; Arginine; Blood Chemical Analysis; Blood Coagulation; Caseins; Cattle; Cyclohexanecarboxylic Acids; Fibrinogen; Fibrinolysin; Fibrinolytic Agents; Humans; Iodine Isotopes; Peptide Hydrolases; Plasminogen; Streptokinase; Thrombin; Urea | 1968 |
Differential specificities of the thrombin, plasmin and trypsin with regard to synthetic and natural substrates and inhibitors.
Topics: Amino Acids; Animals; Arginine; Blood Coagulation Tests; Cattle; Esters; Fibrin; Fibrinogen; Fibrinolysin; Fibrinolysis; Glycine max; Hydrolysis; Lysine; Peptides; Structure-Activity Relationship; Thrombin; Tosyl Compounds; Trypsin; Trypsin Inhibitors | 1972 |
[Quick photometric assay for plasminogen in citrated plasma].
Topics: Arginine; Benzoates; Esterases; Female; Fibrinogen; Fibrinolysin; Humans; In Vitro Techniques; Methods; Plasminogen; Spectrophotometry; Streptokinase | 1971 |
Degradation of human fibrinogen by plasms alpha2-macroglobulin-enzyme complexes.
Topics: Acetates; Aminocaproates; Antibodies; Arginine; Benzoates; Chromatography, DEAE-Cellulose; Chromatography, Gel; Electrophoresis, Polyacrylamide Gel; Esterases; Fibrinogen; Fibrinolysin; Fibrinolytic Agents; Glycine; Humans; Immunoelectrophoresis; Lysine; Macroglobulins; Plasminogen; Streptodornase and Streptokinase; Tosyl Compounds; Trypsin Inhibitors | 1973 |
Studies on the mechanism of action of synthetic antifibrinolytics. A comparison with the action of derivatives of benzamidine on the fibrinolytic process.
Topics: Aminocaproates; Anilides; Animals; Antifibrinolytic Agents; Arginine; Benzoates; Caseins; Cattle; Cyclohexanecarboxylic Acids; Electrophoresis, Polyacrylamide Gel; Fibrin; Fibrinogen; Fibrinolysin; Fibrinolysis; Hydrolysis; Methylamines; Nitro Compounds; Plasminogen; Streptokinase; Thrombin; Trypsin Inhibitors | 1973 |
On the physiological role of 2 -macroglobulin.
Topics: Angiotensin II; Arginine; Blood Coagulation Disorders; Blood Coagulation Tests; Blood Proteins; Caseins; Chromatography, Gel; Chymotrypsinogen; Enzyme Activation; Esters; Fibrin; Fibrinogen; Hemoglobins; Humans; Hydrolysis; Macroglobulins; Pancreatitis; Protein Binding; Protein Denaturation; Thrombin; Trypsin; Trypsin Inhibitors; Trypsinogen; Vasopressins | 1973 |
[Chemical structure of fibrinogen in modified chickens].
Topics: Amino Acids; Animals; Arginine; Avian Leukosis Virus; Binding Sites; Blood Transfusion; Chickens; Electrophoresis; Fibrinogen; Glycopeptides; Glycoproteins; Methods; Neuraminic Acids; Phenotype; Pronase; Protein Conformation | 1973 |
The activation of coagulation by extracts of mucus: a possible pathway of intravascular coagulation accompanying adenocarcinomas.
Topics: Adenocarcinoma, Mucinous; Animals; Arginine; Blood Coagulation; Blood Coagulation Tests; Brain Chemistry; Bronchi; Chemical Precipitation; Disseminated Intravascular Coagulation; Esterases; Factor V Deficiency; Factor VII; Factor VII Deficiency; Factor X; Fibrinogen; Hemophilia B; Humans; Hypoprothrombinemias; Kaolin; Mucins; Mucus; Muramidase; Phospholipids; Prothrombin; Rabbits; Thromboplastin; Time Factors; Venoms | 1973 |
Increased amount of arginine in plasma clot after administration of protamine to dogs.
Topics: Animals; Arginine; Blood Coagulation; Dogs; Fibrin; Fibrinogen; Protamines | 1974 |
The specificity of the fibrinogen-thrombin reaction.
Topics: Animals; Arginine; Binding Sites; Catalysis; Cattle; Chemical Phenomena; Chemistry; Fibrinogen; Glycine; Humans; Hydrolysis; Peptide Hydrolases; Peptides; Thiocyanates; Thrombin | 1974 |
Action of trypsin on amidinated fibrinogen.
Topics: Amidines; Animals; Arginine; Cattle; Fibrinogen; Lysine; Trypsin | 1974 |
A plasma protein fractionation procedure for use in studies of protein metabolism.
Topics: Animals; Arginine; Blood Proteins; Carbonates; Chemical Fractionation; Chromatography, Gel; Fatty Acids; Fibrinogen; Fractional Precipitation; Glycoproteins; Hexosamines; Hexoses; Macroglobulins; Molecular Weight; Phosphorus; Proteins; Rats; Serum Albumin; Transferrin; Urea | 1974 |
An evaluation of the utility of benzoyl-DL-arginine-beta-naphthyl-amide for the assay of thrombin activity in blood.
Topics: Animals; Arginine; Benzamides; Cattle; Coronary Disease; Coumarins; Factor VIII; Fibrinogen; Hirudins; Humans; Hydrolysis; Naphthalenes; Protein Binding; Prothrombin; Serum Albumin; Thrombin; Thromboplastin | 1974 |
The effects of chemical inhibitors and ionizing radiation on arvin activity.
Topics: Amino Acids; Antivenins; Arginine; Benzoates; Chromatography, Gel; Chromatography, Ion Exchange; Fibrinogen; Fluorides; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Peptide Hydrolases; Protease Inhibitors; Radiation Effects; Spectrophotometry; Temperature; Tosyl Compounds; Venoms | 1972 |
Isolation of thrombin-like activity from the venom of Trimeresurus okinavensis.
Topics: Amino Acids; Animals; Arginine; Autoanalysis; Blood Coagulation Tests; Caseins; Chromatography, Gel; Chromatography, Ion Exchange; Esterases; Esters; Fibrinogen; Fibrinolysis; Isoelectric Focusing; Molecular Weight; Peptide Hydrolases; Snakes; Thrombin; Tosyl Compounds; Tryptophan; Venoms | 1972 |
The arginine content in fibrin clots and fibrinolysis in neoplastic diseases.
Topics: Arginine; Fibrin; Fibrinogen; Fibrinolysis; Humans; Neoplasm Proteins; Neoplasms; Protein Binding | 1973 |
On the reaction of purified bovine thrombin with N-acetylimidazole.
Topics: Acetates; Acetylation; Animals; Arginine; Binding Sites; Binding, Competitive; Blood Coagulation; Cattle; Chemical Phenomena; Chemistry; Drug Stability; Enzyme Activation; Esterases; Esters; Fibrinogen; Hydrogen-Ion Concentration; Imidazoles; Protein Conformation; Spectrophotometry; Structure-Activity Relationship; Thrombin; Time Factors; Tosyl Compounds; Tyrosine | 1973 |
Enzymatic basis for platelet aggregation and release: the significance of the 'platelet atmosphere' and the relationship between platelet function and blood coagulation.
Topics: Acetates; Adenosine Diphosphate; Arginine; Blood Coagulation; Blood Coagulation Factors; Blood Platelets; Chlorine; Factor XIII; Fibrin; Fibrinogen; Hemostasis; Humans; Hydrolysis; In Vitro Techniques; Male; Plasma; Platelet Adhesiveness; Prothrombin; Thrombin; Tosyl Compounds; Urea | 1974 |
Effect of endotoxin on plasma albumin and fibrinogen synthesis rates in rabbits as measured by the [14C] carbonate method.
Topics: Animals; Arginine; Carbon Isotopes; Carbonates; Endotoxins; Fibrinogen; Guanidines; Male; Methods; Rabbits; Serum Albumin; Serum Albumin, Radio-Iodinated; Shigella dysenteriae; Stimulation, Chemical; Time Factors; Urea | 1968 |
The nature of the rennin-sensitive bond in casein and its possible relation to sensitive bonds in other proteins.
Topics: Arginine; Caseins; Chromatography, Gel; Chymosin; Fibrinogen; Light; Methionine; Phenylalanine; Thrombin | 1968 |
Observations concerning the substrate specificity of Arvin.
Topics: Acetates; Amino Acids; Animals; Anticoagulants; Arginine; Benzoates; Blood Coagulation; Cattle; Endopeptidases; Enzyme Activation; Esters; Fibrinogen; Kinetics; Lysine; Methanol; Plasminogen; Protein Binding; Snakes; Structure-Activity Relationship; Thrombin; Tosyl Compounds; Venoms | 1972 |
Multiple active forms of thrombin. II. Mechanism of production from prothrombin.
Topics: Ammonium Sulfate; Animals; Arginine; Blood Coagulation; Cattle; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Detergents; Disulfides; Drug Stability; Electrophoresis; Electrophoresis, Disc; Enzyme Activation; Fibrinogen; Glycerol; Guanidines; Isoelectric Focusing; Isoflurophate; Kinetics; Mercaptoethanol; Models, Biological; Molecular Weight; Oxidation-Reduction; Prothrombin; Sulfonic Acids; Sulfuric Acids; Thrombin; Toluene; Urea | 1971 |
Mechanism of action of thrombin on fibrinogen. II. Kinetics of hydrolysis of fibrinogen-like peptides by thrombin and trypsin.
Topics: Amino Acid Sequence; Animals; Arginine; Cattle; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Chromatography, Paper; Chromatography, Thin Layer; Esters; Fibrinogen; Hydrolysis; Kinetics; Methylcellulose; Peptides; Sulfonic Acids; Thrombin; Trypsin | 1971 |
Some catalytic properties of IRC-50 Arvin.
Topics: Animals; Anticoagulants; Arginine; Binding Sites; Blood Coagulation; Chromatography, Ion Exchange; Esterases; Esters; Fibrinogen; Fluorides; Isoflurophate; Serine; Snakes; Sulfonic Acids; Venoms | 1971 |
Direct measurement of the rates of synthesis of plasma proteins in control subjects and patients with gastrointestinal protein loss.
Topics: Amyotrophic Lateral Sclerosis; Arginine; Bicarbonates; Blood Proteins; Carbon Isotopes; Crohn Disease; Fibrinogen; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Protein-Losing Enteropathies; Serum Albumin, Radio-Iodinated; Transferrin; Urea | 1968 |
A plasminogen activator in mammalian bile.
Topics: Animals; Arginine; Bile; Caseins; Chromatography, Gel; Cyclohexanes; Dogs; Female; Fibrin; Fibrinogen; Fibrinolysis; Plasminogen; Rabbits; Streptokinase; Thrombin; Toluene; Urea | 1969 |
The effect of growth hormone on fibrinogen synthesis.
Topics: Animals; Arginine; Carbon Isotopes; Carbonates; Computers, Analog; Fibrinogen; Growth Hormone; Guanidines; Iodine Isotopes; Male; Plasma Volume; Rats; Serum Albumin; Urea | 1970 |
[The peptide pattern of highly purified fibrinogen from the blood of newborns and adults].
Topics: Adult; Age Factors; Arginine; Blood Protein Electrophoresis; Chemical Phenomena; Chemistry; Chromatography; Fetus; Fibrinogen; Humans; Hydrogen-Ion Concentration; Infant, Newborn; Lysine; Peptides; Trypsin | 1968 |
Mechanism of action of proteolytic enzymes in the plasminogen-plasmin system.
Topics: Animals; Arginine; Cattle; Chymotrypsin; Esters; Fibrin; Fibrinogen; Hemoglobins; Humans; Plasma; Plasminogen; Spectrophotometry; Streptodornase and Streptokinase; Swine; Time Factors; Trypsin; Tyrosine | 1969 |
[Substitution of antithrombin III by synthetic thrombin inhibitors].
Topics: Animals; Antithrombin III; Antithrombin III Deficiency; Arginine; Carbon Tetrachloride Poisoning; Fibrinogen; Heparin; Phenylpyruvic Acids; Pipecolic Acids; Platelet Count; Rats; Sulfonamides; Thrombin; Thrombosis | 1984 |
Comparative studies on thrombin inhibitors in experimental microthrombosis.
Topics: 4-Aminobenzoic Acid; Animals; Arginine; Dipeptides; Female; Fibrinogen; Hirudins; Kinetics; Lung; Male; Microcirculation; para-Aminobenzoates; Piperidines; Rats; Rats, Inbred Strains; Thrombin; Thrombosis | 1983 |
[Fibrinogen Bern II: hereditary fibrinogen variant with amino acid substitution of arginine replaced by histidine in position 16 of the A alpha chain].
Topics: Afibrinogenemia; Amino Acids; Arginine; Chemical Phenomena; Chemistry; Female; Fibrinogen; Fibrinogens, Abnormal; Fibrinopeptide A; Genetic Variation; Histidine; Humans; Male; Switzerland; Thrombin | 1983 |
A clinical trial of MD-805, a synthetic thrombin inhibitor, for the treatment of DIC.
Topics: Antithrombins; Arginine; Chemical Phenomena; Chemistry; Child; Disseminated Intravascular Coagulation; Female; Fibrinogen; Humans; Meningoencephalitis; Partial Thromboplastin Time; Pipecolic Acids; Platelet Count; Prothrombin Time; Pseudomonas Infections; Sepsis; Sulfonamides; Thrombin | 1983 |
Novel structure elucidation strategy for genetically abnormal fibrinogens with incomplete fibrinopeptide release as applied to fibrinogen Schwarzach.
Topics: Amino Acids; Arginine; Chromatography, High Pressure Liquid; Cysteine; Fibrinogen; Fibrinogens, Abnormal; Fibrinopeptide A; Genetic Variation; Heterozygote; Humans | 1983 |
Identification of a congenital dysthrombin, thrombin Quick.
Topics: Antithrombin III; Arginine; Calcium; Chromatography, Gel; Dansyl Compounds; Electrophoresis, Polyacrylamide Gel; Factor VIII; Factor X; Factor Xa; Fibrinogen; Humans; Hypoprothrombinemias; Phospholipids; Thrombin | 1980 |
Inhibition of thrombin cleavage of fibrinogen by polyestradiol phosphate; interaction with the crucial arginine residues in fibrinogen required for enzymic cleavage.
Topics: Arginine; Estradiol; Fibrinogen; Kinetics; Thrombin | 1982 |
Fibrinogen Petoskey, a dysfibrinogenemia characterized by replacement of Arg-A alpha 16 by a histidyl residue. Evidence for thrombin-catalyzed hydrolysis at a histidyl residue.
Topics: Afibrinogenemia; Amino Acids; Arginine; Carboxypeptidases; Fibrinogen; Fibrinogens, Abnormal; Histidine; Humans; Peptide Fragments; Thrombin | 1981 |
Steady-state kinetic study of the bovine thrombin-fibrinogen interaction.
Topics: Amino Acid Sequence; Animals; Arginine; Cattle; Cyanogen Bromide; Fibrinogen; Glycine; Kinetics; Mathematics; Peptide Fragments; Substrate Specificity; Thrombin | 1980 |
Platelet aggregation inhibition by mononuclear leukocytes.
Topics: 6-Ketoprostaglandin F1 alpha; Antibodies, Monoclonal; Arginine; Collagen; Culture Media, Conditioned; Cytochrome c Group; Fibrinogen; Hemoglobins; Humans; Leukocytes, Mononuclear; Lymphocyte Function-Associated Antigen-1; Lymphocyte Subsets; Monocytes; P-Selectin; Platelet Aggregation; Platelet Membrane Glycoproteins; Superoxide Dismutase; Thrombin | 1994 |
The effect of nitric oxide synthase inhibition on the plasma fibrinolytic system in septic shock in rats.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Coagulation; Disseminated Intravascular Coagulation; Fibrinogen; Fibrinolysis; Lipopolysaccharides; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Plasminogen Inactivators; Platelet Count; Rats; Rats, Wistar; Shock, Septic | 1994 |
Effect of inhibition of nitric oxide synthesis on the uptake of LDL and fibrinogen by arterial walls and other organs of the rat.
Topics: Animals; Aorta; Arginine; Arteries; Blood Pressure; Body Weight; Dose-Response Relationship, Drug; Fibrinogen; Heart; Lipoproteins, LDL; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar | 1995 |
Complexoproductive and antiheparin properties of low density lipoproteins (LDL). VI. Antiheparin activity in blood plasma of different species of vertebrates.
Topics: Animals; Arginine; Blood Proteins; Cattle; Chickens; Dogs; Fibrinogen; Heparin Antagonists; Horses; Humans; Lipoproteins, LDL; Mammals; Orosomucoid; Reference Values; Serum Globulins; Sheep; Species Specificity; Swine | 1993 |
Hereditary renal amyloidosis associated with a mutant fibrinogen alpha-chain.
Topics: Adult; Amino Acid Sequence; Amyloidosis; Arginine; Base Sequence; DNA; Exons; Female; Fibrinogen; Genetic Variation; Humans; Kidney Diseases; Leucine; Macromolecular Substances; Male; Middle Aged; Molecular Sequence Data; Oligodeoxyribonucleotides; Pedigree; Point Mutation; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length | 1993 |
The structure of alpha-thrombin inhibited by a 15-mer single-stranded DNA aptamer.
Topics: Amino Acid Sequence; Arginine; Base Sequence; Binding Sites; DNA, Single-Stranded; Fibrinogen; Glutamates; Glutamic Acid; Heparin; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Protein Conformation; Protein Structure, Tertiary; Thrombin; X-Ray Diffraction | 1993 |
Synthetic selective inhibitors of thrombin.
Topics: Amino Acid Sequence; Animals; Antithrombin III; Antithrombins; Arginine; Cattle; Dansyl Compounds; Fibrin; Fibrinogen; Heparin; Humans; Infant, Newborn; Kinetics; Molecular Sequence Data; Molecular Structure; Oligopeptides; Pipecolic Acids; Structure-Activity Relationship; Substrate Specificity; Sulfonamides; Thrombin | 1993 |
The polymerization of fibrinogen Dusart (A alpha 554 Arg-->Cys) after removal of carboxy terminal regions of the A alpha-chains.
Topics: Albumins; Arginine; Cystine; Fibrin; Fibrinogen; Fibrinogens, Abnormal; Molecular Structure; Polymers | 1993 |
Calcium ion modulation of meizothrombin autolysis at Arg55-Asp56 and catalytic activity.
Topics: Arginine; Binding Sites; Blood Coagulation; Calcium; Catalysis; Enzyme Precursors; Fibrinogen; Humans; Prothrombin; Recombinant Proteins; Structure-Activity Relationship; Thrombin | 1996 |
Renal denervation prevents intraglomerular platelet aggregation and glomerular injury induced by chronic inhibition of nitric oxide synthesis.
Topics: Albuminuria; Animals; Arginine; Denervation; Enzyme Inhibitors; Fibrinogen; Histocytochemistry; Kidney; Kidney Diseases; Kidney Glomerulus; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Platelet Aggregation; Rats; Rats, Sprague-Dawley | 1996 |
Fibrinogen Claro--another dysfunctional fibrinogen variant with gamma 275 arginine-->histidine substitution.
Topics: Adult; Afibrinogenemia; Arginine; Base Sequence; Blood Protein Electrophoresis; DNA Mutational Analysis; Female; Fibrinogen; Fibrinogens, Abnormal; Fibrinopeptide A; Histidine; Humans; Male; Molecular Sequence Data; Pedigree; Point Mutation | 1996 |
[Familial Binswanger-type encephalopathy with Sneddon syndrome].
Topics: Adult; Antithrombin III; Antithrombins; Arginine; Cerebral Infarction; Dementia; Factor V; Female; Fibrinogen; Humans; Male; Migraine Disorders; Peptide Hydrolases; Pipecolic Acids; Sneddon Syndrome; Sulfonamides; Syndrome | 1996 |
Crystal structure of two new bifunctional nonsubstrate type thrombin inhibitors complexed with human alpha-thrombin.
Topics: Amino Acid Sequence; Antithrombins; Arginine; Binding Sites; Coagulants; Crystallization; Crystallography, X-Ray; Fibrinogen; Hirudins; Humans; Hydrogen Bonding; Hydrolysis; Naphthalenesulfonates; Peptide Fragments; Peptides; Pipecolic Acids; Protein Structure, Secondary; Serine Proteinase Inhibitors; Sulfonamides; Thrombin | 1996 |
Endogenous endothelium-derived relaxing factor inhibits platelet adhesion under whole blood flow conditions ex vivo.
Topics: Animals; Arginine; Blood Circulation; Blood Platelets; Blood Pressure; Carbachol; Cyclic AMP; Cyclic GMP; Enzyme Inhibitors; Fibrinogen; Hemoglobins; In Vitro Techniques; Indicators and Reagents; Injections, Intravenous; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Parasympathomimetics; Platelet Adhesiveness; Rats; Rats, Sprague-Dawley | 1995 |
Attenuation by prolonged nitric oxide synthase inhibition of the enhancement of fibrinolysis caused by environmental stress in the rat.
Topics: Animals; Arginine; Blood Coagulation Factors; Blood Proteins; Drug Interactions; Enzyme Inhibitors; Fibrinogen; Fibrinolysis; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Platelet Count; Rats; Rats, Wistar; Serum Globulins; Stereoisomerism; Stress, Physiological | 1996 |
Evaluation of arginine-glycine-aspartate-containing peptides as inhibitors of equine platelet function.
Topics: Animals; Arginine; Aspartic Acid; Aspirin; Blood Coagulation; Blood Platelets; Dose-Response Relationship, Drug; Fibrinogen; Glycine; Horses; Oligopeptides; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Platelet Glycoprotein GPIIb-IIIa Complex | 1997 |
Habutobin splits the Arg16-Gly17 bond in the A alpha chain of rabbit fibrinogen.
Topics: Amino Acid Sequence; Animals; Arginine; Cattle; Crotalid Venoms; Dogs; Fibrinogen; Glycine; Humans; Molecular Sequence Data; Rabbits; Rats; Serine Endopeptidases | 1997 |
Effect of L-arginine on in vitro plasmin-generation and fibrinogenolysis.
Topics: Arginine; Fibrinogen; Fibrinolysin; Humans; Kinetics | 1997 |
Use of conformationally restricted benzamidines as arginine surrogates in the design of platelet GPIIb-IIIa receptor antagonists.
Topics: Arginine; Benzamidines; Enzyme-Linked Immunosorbent Assay; Fibrinogen; Humans; Indicators and Reagents; Models, Molecular; Molecular Conformation; Molecular Structure; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Structure-Activity Relationship | 1997 |
Fibrinogen Poissy I: a new case of the A alpha Arg 16His fibrinogen variant.
Topics: Adult; Arginine; Disseminated Intravascular Coagulation; Female; Fibrinogen; Histidine; Humans; Point Mutation; Pregnancy; Sequence Analysis, DNA | 1997 |
Electrospray ionisation mass spectrometry facilitates detection of fibrinogen (Bbeta 14 Arg --> Cys) mutation in a family with thrombosis.
Topics: Adult; Amino Acid Substitution; Arginine; Catalysis; Cysteine; Family Health; Female; Fibrin; Fibrinogen; Fibrinopeptide A; Fibrinopeptide B; Glycoproteins; Heterozygote; Humans; Mass Spectrometry; Molecular Weight; Mutation; Point Mutation; Polymerase Chain Reaction; Sequence Analysis; Thrombin; Thrombosis | 1997 |
Interaction of vaccinia virus complement control protein with human complement proteins: factor I-mediated degradation of C3b to iC3b1 inactivates the alternative complement pathway.
Topics: Arginine; Binding Sites; Complement C3-C5 Convertases; Complement C3b; Complement C3b Inactivator Proteins; Complement C3c; Complement C3d; Complement Factor H; Complement Pathway, Alternative; Fibrinogen; Humans; Hydrolysis; Receptors, Complement; Receptors, Complement 3b; Recombinant Proteins; Serine; Vaccinia virus; Viral Proteins | 1998 |
Effects of antithrombin on Binswanger's disease with antiphospholipid antibody syndrome.
Topics: Antiphospholipid Syndrome; Antithrombin III; Antithrombins; Arginine; Basal Ganglia Diseases; Dementia, Multi-Infarct; Female; Fibrinogen; Hemostasis; Humans; Magnetic Resonance Imaging; Middle Aged; Peptide Hydrolases; Pipecolic Acids; Sulfonamides | 1999 |
A new type of Ser substitution for gamma Arg-275 in fibrinogen Kamogawa I characterized by impaired fibrin assembly.
Topics: Adult; Amino Acid Substitution; Arginine; Blood Coagulation; Female; Fibrin; Fibrinogen; Humans; Point Mutation; Serine | 1999 |
Hypofibrinogenemia associated with a heterozygous missense mutation gamma153Cys to arg (Matsumoto IV): in vitro expression demonstrates defective secretion of the variant fibrinogen.
Topics: Adult; Afibrinogenemia; Animals; Arginine; Base Sequence; CHO Cells; Cricetinae; Cysteine; Female; Fibrinogen; Gene Expression; Heterozygote; Humans; Molecular Sequence Data; Mutation, Missense | 1999 |
Fibrinogen Bbeta14 Arg-->Cys: further evidence for a role in thrombosis.
Topics: Adult; Arginine; Cysteine; Female; Fibrinogen; Humans; Male; Point Mutation; Thrombosis | 1999 |
Fused bicyclic Gly-Asp beta-turn mimics with potent affinity for GPIIb-IIIa. Exploration of the arginine isostere.
Topics: Acetates; Adenosine Diphosphate; Amidines; Animals; Arginine; Benzamidines; Biological Availability; Drug Evaluation; Enzyme-Linked Immunosorbent Assay; Fibrinogen; Humans; Inhibitory Concentration 50; Models, Molecular; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Prodrugs; Protein Binding; Protein Structure, Secondary; Rats; Stereoisomerism; Tetralones | 2000 |
Spatiotemporal dynamics of fibrin formation and spreading of active thrombin entering non-recalcified plasma by diffusion.
Topics: alpha-Macroglobulins; Antithrombins; Arginine; Blood Coagulation; Calcium; Coumarins; Diffusion; Fibrin; Fibrinogen; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Humans; Kinetics; Models, Theoretical; Pipecolic Acids; Plasma; Solutions; Sulfonamides; Thrombin | 2000 |
Comparison of pathogenic properties between two types of arginine-specific cysteine proteinases (gingipains-R) from Porphyromonas gingivalis.
Topics: Adhesins, Bacterial; Arginine; Bacteroidaceae Infections; Capillary Permeability; Cysteine Endopeptidases; Fibrinogen; Fibrinolysis; Gingipain Cysteine Endopeptidases; Hemagglutinins; Humans; Periodontal Diseases; Phospholipids; Porphyromonas gingivalis; Substrate Specificity | 2000 |
Activation of human prothrombin by arginine-specific cysteine proteinases (Gingipains R) from porphyromonas gingivalis.
Topics: Adhesins, Bacterial; Arginine; Binding Sites; Blood Coagulation; Blotting, Western; Cell Adhesion; Cysteine Endopeptidases; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Enzyme Activation; Fibrinogen; Gingipain Cysteine Endopeptidases; Hemagglutinins; Humans; Interleukin-1; Kinetics; Plasma; Porphyromonas gingivalis; Prothrombin; Sequence Analysis, Protein; Thrombin; Time Factors | 2001 |
Synthesis and characterization of positively charged tPA as a prodrug using heparin/protamine-based drug delivery system.
Topics: alpha-2-Antiplasmin; Antibodies; Arginine; Cross-Linking Reagents; Cysteine; Drug Stability; Fibrinogen; Fibrinolytic Agents; Heparin; Humans; In Vitro Techniques; Kinetics; Oligopeptides; Plasminogen; Plasminogen Activators; Prodrugs; Protamines; Succinimides; Tissue Plasminogen Activator | 2000 |
An antibody that binds to primary specific pocket-associated structure in the active site of bovine thrombin.
Topics: Animals; Antibodies, Monoclonal; Arginine; Binding Sites; Binding, Competitive; Cattle; Chromatography, Affinity; Cloning, Molecular; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Fibrinogen; Hybridomas; Immunoglobulin G; Mice; Mice, Inbred BALB C; Pipecolic Acids; Protein Binding; Rabbits; Rats; Rats, Wistar; Spleen; Sulfonamides; Thrombin | 2002 |
[Fibrinogen variation: a heterozygote dysfibrinogenemia with Arg-->His substitution in position 16 of the Aalpha chain].
Topics: Amino Acid Substitution; Arginine; Female; Fibrinogen; Genetic Carrier Screening; Genetic Variation; Histidine; Humans; Male; Pedigree | 2002 |
Haemorheological and endothelial-dependent alterations in heart failure after ACE inhibitor, calcium antagonist and beta blocker.
Topics: Adrenergic beta-Antagonists; Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Arginine; Blood Viscosity; Calcium; Carbazoles; Carvedilol; Citrulline; Erythrocytes; Female; Fibrinogen; Heart Failure; Humans; Male; Middle Aged; Nitric Oxide Synthase; Propanolamines; Ramipril; Time Factors; Treatment Outcome; Vascular Cell Adhesion Molecule-1; Vasodilator Agents | 2002 |
Familial hypofibrinogenaemia associated with heterozygous substitution of a conserved arginine residue; Bbeta255 Arg-->His (Fibrinogen Merivale).
Topics: Afibrinogenemia; Amino Acid Sequence; Arginine; Child; Electrophoresis, Polyacrylamide Gel; Fibrinogen; Fibrinogens, Abnormal; Genotype; Heterozygote; Histidine; Humans; Male; Molecular Sequence Data; Pedigree; Peptide Fragments; Point Mutation; Sequence Analysis, DNA; Spectrometry, Mass, Electrospray Ionization | 2003 |
Hemostatic analysis of a patient undergoing off-pump coronary artery bypass surgery with argatroban anticoagulation.
Topics: Aged; Anticoagulants; Arginine; Colitis; Coronary Artery Bypass; Fatal Outcome; Fibrinogen; Hemostasis; Heparin; Humans; International Normalized Ratio; Male; Partial Thromboplastin Time; Pipecolic Acids; Platelet Count; Prothrombin Time; Sulfonamides; Thrombelastography; Thrombin; Thrombocytopenia; Whole Blood Coagulation Time | 2003 |
Anticoagulant action of TAMe and AFIF.
Topics: Anticoagulants; Arginine; Coagulants; Fibrinogen; Hemostatics; Humans | 1961 |
Enzymatic activities associated with clotting of fibrinogen by staphylocoagulase and coagulase-reacting factor and their inhibition by disopropylfluophosphate.
Topics: Arginine; Blood Coagulation; Coagulase; Enzymes; Fibrinogen; Fluorides; Phosphates; Staphylococcus; Thrombin | 1962 |
Significance of cryoprofibrin in fibrinogen-fibrin conversion.
Topics: Arginine; Blood Coagulation Factors; Cold Temperature; Fibrin; Fibrinogen; Fibrinopeptide A; Fibrinopeptide B; Humans; Thrombin | 1962 |
MEASUREMENT OF SYNTHESIS RATES OF LIVER-PRODUCED PLASMA PROTEINS.
Topics: Animals; Arginine; Blood Proteins; Carbon Dioxide; Carbon Isotopes; Carbonates; Chromatography; Fibrinogen; gamma-Globulins; Iodine Isotopes; Liver; Manometry; Proteins; Rabbits; Research; Serum Albumin; Serum Albumin, Radio-Iodinated; Urea | 1963 |
AGGREGATION OF FIBRIN AND FIBRINOGEN BY TAME.
Topics: Arginine; Blood Coagulation; Coagulants; Cold Temperature; Fibrin; Fibrinogen; Hemostatics; Heparin; Humans; Hydrogen-Ion Concentration; Pharmacology; Thrombin | 1964 |
Characterization of the specificity of arginine-specific gingipains from Porphyromonas gingivalis reveals active site differences between different forms of the enzymes.
Topics: Adhesins, Bacterial; Amino Acid Substitution; Arginine; Binding Sites; Catalytic Domain; Cysteine Endopeptidases; Fibrinogen; Fibronectins; Gingipain Cysteine Endopeptidases; Hemagglutinins; Humans; Isoenzymes; Laminin; Models, Molecular; Porphyromonas gingivalis; Protein Binding; Substrate Specificity | 2003 |
A natural prothrombin mutant reveals an unexpected influence of A-chain structure on the activity of human alpha-thrombin.
Topics: Animals; Arginine; Blood Platelets; Catalytic Domain; Cell Membrane; Chromatography, High Pressure Liquid; COS Cells; DNA; Fibrinogen; Fibrinopeptide A; Gene Deletion; Humans; Hydrolysis; Hypoprothrombinemias; Ions; Kinetics; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Protein Binding; Protein C; Protein Conformation; Protein Structure, Secondary; Prothrombin; Sodium; Sodium Chloride; Thrombin; Time Factors; Transfection | 2004 |
B beta Glu397 and B beta Asp398 but not B beta Asp432 are required for "B:b" interactions.
Topics: Alanine; Arginine; Batroxobin; Calcium; Catalysis; Crystallography, X-Ray; Fibrin Fibrinogen Degradation Products; Fibrinogen; Fibrinopeptide A; Fibrinopeptide B; Glutamic Acid; Humans; Mutagenesis, Site-Directed; Polymers; Protein Binding; Protein Subunits; Recombinant Proteins; Thrombin | 2004 |
Recombinant fibrinogen, gamma275Arg-->Cys, exhibits formation of disulfide bond with cysteine and severely impaired D:D interactions.
Topics: Amino Acid Substitution; Arginine; Base Sequence; Binding Sites; Catalysis; Cysteine; Disulfides; DNA Primers; Factor XIIIa; Fibrin; Fibrinogen; Humans; Kinetics; Microscopy, Electron, Scanning; Molecular Weight; Mutagenesis, Site-Directed; Recombinant Proteins; Thrombin | 2004 |
Influence of arginine deimination on antigenicity of fibrinogen.
Topics: Adjuvants, Immunologic; Animals; Antibody Formation; Arginine; Arthritis, Rheumatoid; Autoantibodies; Autoantigens; Autoimmunity; Fibrinogen; Hydrolases; Imines; Mice; Mice, Inbred BALB C; Protein-Arginine Deiminases | 2004 |
Prothrombin residues 473-487 contribute to factor Va binding in the prothrombinase complex.
Topics: Animals; Anisotropy; Arginine; Binding Sites; Blood Coagulation; Blotting, Western; Chymotrypsin; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Enzyme Precursors; Enzyme-Linked Immunosorbent Assay; Factor Va; Factor Xa; Fibrinogen; Fluorescein; Humans; Kinetics; Models, Molecular; Partial Thromboplastin Time; Peptides; Protein Binding; Prothrombin; Spectrometry, Fluorescence; Spectrophotometry; Thrombin; Thromboplastin; Viper Venoms | 2004 |
Growth hormone deficiency predicts cardiovascular risk in young adults treated for acute lymphoblastic leukemia in childhood.
Topics: Adolescent; Apolipoproteins B; Arginine; Blood Glucose; Body Height; Cardiovascular Diseases; Carotid Arteries; Child; Child, Preschool; Cholesterol, LDL; Echocardiography, Doppler; Exercise; Female; Fibrinogen; Growth Hormone-Releasing Hormone; Human Growth Hormone; Humans; Infant; Insulin; Leptin; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Predictive Value of Tests; Risk Factors; Triglycerides | 2004 |
Comparison of enzymatic properties between hPADI2 and hPADI4.
Topics: Amino Acid Sequence; Arginine; Arthritis, Rheumatoid; Calcium; Catalysis; Citrulline; Fibrinogen; Filaggrin Proteins; Humans; Hydrogen-Ion Concentration; Hydrolases; Immunohistochemistry; Intermediate Filament Proteins; Kinetics; Molecular Sequence Data; Protein Denaturation; Protein-Arginine Deiminase Type 2; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; Substrate Specificity; Synovial Membrane | 2005 |
[Inherited dysfibrinogenemia caused by Arg275His in the beta chain of fibrinogen].
Topics: Adult; Afibrinogenemia; Amino Acid Substitution; Arginine; DNA Mutational Analysis; Female; Fibrinogen; Histidine; Humans; Male; Pedigree; Phenotype | 2005 |
Liver histology of an afibrinogenemic patient with the Bbeta-L353R mutation showing no evidence of hepatic endoplasmic reticulum storage disease (ERSD); comparative study in COS-1 cells of the intracellular processing of the Bbeta-L353R fibrinogen vs. the
Topics: Adolescent; Animals; Arginine; COS Cells; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Fibrinogen; Genotype; Glycoside Hydrolases; Humans; Immunohistochemistry; Immunoprecipitation; Leucine; Liver; Liver Diseases; Male; Metabolism, Inborn Errors; Microscopy, Electron; Mutation; Mutation, Missense; Phenotype; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Transfection | 2005 |
Mechanism of antithrombotic effect of heparin and antithrombin in balloon-injured arteries.
Topics: Angiography; Animals; Antithrombins; Arginine; Arteries; Catheterization; Dogs; Fibrinogen; Fibrinolytic Agents; Heparin; Iliac Artery; Microscopy, Fluorescence; Partial Thromboplastin Time; Pipecolic Acids; Prothrombin Time; Sulfonamides; Thrombosis | 2005 |
Biochemical characterization of human kallikrein 8 and its possible involvement in the degradation of extracellular matrix proteins.
Topics: Arginine; Caseins; Collagen Type IV; Escherichia coli; Extracellular Matrix Proteins; Female; Fibrinogen; Fibronectins; Gelatin; Humans; Kallikreins; Kinetics; Recombinant Fusion Proteins; Serine Proteinase Inhibitors; Substrate Specificity; Tissue Plasminogen Activator | 2005 |
Functional characterization of the complement control protein homolog of herpesvirus saimiri: ARG-118 is critical for factor I cofactor activities.
Topics: Arginine; Complement C3b; Complement Factor H; Escherichia coli; Fibrinogen; Herpesvirus 2, Saimiriine; Humans; Kinetics; Lectins; Lysine; Membrane Glycoproteins; Models, Molecular; Mutagenesis, Site-Directed; Receptors, Complement; Viral Proteins | 2006 |
Fibrinogen gamma375 arg-->trp mutation (fibrinogen aguadilla) causes hereditary hypofibrinogenemia, hepatic endoplasmic reticulum storage disease and cirrhosis.
Topics: Adult; Afibrinogenemia; Amino Acid Sequence; Amino Acid Substitution; Arginine; Endoplasmic Reticulum; Family Health; Fibrinogen; Hepatocytes; Humans; Inclusion Bodies; Liver; Liver Cirrhosis; Male; Middle Aged; Molecular Sequence Data; Mutation, Missense; Point Mutation; Tryptophan | 2006 |
Fibrinogen Nottingham II: a novel Bbeta Arg264gly substitution causing hypofibrinogenaemia.
Topics: Adult; Afibrinogenemia; Arginine; Binding Sites; Calcium; Crystallography, X-Ray; Female; Fibrinogen; Humans; Models, Molecular; Mutation; Peptides; Protein Structure, Tertiary; Spectrometry, Mass, Electrospray Ionization | 2006 |
A Bbeta 14 Arg --> Cys fibrinogen variant in a patient with thrombotic complications (fibrinogen St-Germain III).
Topics: Adult; Arginine; Cysteine; Fibrinogen; Heterozygote; Humans; Male; Mutation; Pedigree; Pulmonary Embolism; Risk Factors; Thrombophilia; Venous Thrombosis | 2006 |
Hydroxyethyl starch enhances argatroban-mediated decreases in clot propagation and strength by diminishing thrombin-fibrinogen interactions.
Topics: Anticoagulants; Arginine; Blood Coagulation; Cardiopulmonary Bypass; Drug Synergism; Fibrinogen; Hemostasis; Heparin; Humans; Hydroxyethyl Starch Derivatives; Pipecolic Acids; Protein Binding; Sulfonamides; Thrombin; Thrombocytopenia | 2007 |
Influence of coagulation factors on extrinsic thrombin generation.
Topics: Arginine; Blood Coagulation Factors; Blood Coagulation Tests; Calcium Chloride; Fibrinogen; Humans; Thrombin; Thromboplastin | 2007 |
BJ-48, a novel thrombin-like enzyme from the Bothrops jararacussu venom with high selectivity for Arg over Lys in P1: Role of N-glycosylation in thermostability and active site accessibility.
Topics: Animals; Arginine; Bothrops; Catalytic Domain; Chromatography, Affinity; Chromatography, Gel; Chromatography, High Pressure Liquid; Crotalid Venoms; Enzyme Stability; Fibrinogen; Glycosylation; Hydrogen-Ion Concentration; Lysine; Serine Endopeptidases; Serine Proteinase Inhibitors; Substrate Specificity; Temperature; Thrombin | 2007 |
Probing the beta-chain hole of fibrinogen with synthetic peptides that differ at their amino termini.
Topics: Amino Acid Sequence; Animals; Arginine; Binding Sites; Chickens; Fibrin; Fibrin Fibrinogen Degradation Products; Fibrinogen; Fibrinolysin; Fibrinolysis; Glycine; Humans; Lampreys; Lysine; Models, Molecular; Molecular Sequence Data; Oligopeptides; Protein Binding; Protein Conformation; Species Specificity; Tissue Plasminogen Activator; Tyrosine | 2007 |
Citrullinated fibrinogen inhibits thrombin-catalysed fibrin polymerization.
Topics: Arginine; Blood Coagulation; Catalysis; Citrulline; Edetic Acid; Fibrin; Fibrinogen; Humans; Inflammation; Kinetics; Peptides; Substrate Specificity; Thrombin; Time Factors | 2008 |
Interaction between thrombin mutant W215A/E217A and direct thrombin inhibitor.
Topics: Amino Acid Substitution; Anticoagulants; Arginine; Enzyme Inhibitors; Fibrinogen; Humans; Mutation, Missense; Pipecolic Acids; Protein Binding; Protein C; Protein Structure, Tertiary; Sulfonamides; Thrombin | 2008 |
Extent of hepatitis E virus elimination is affected by stabilizers present in plasma products and pore size of nanofilters.
Topics: Animals; Arginine; Citrates; Excipients; Feces; Fibrinogen; Filtration; Genotype; Hepatitis E virus; Hot Temperature; Micropore Filters; Nanotechnology; Plasma; RNA, Viral; Serum Albumin; Sodium Chloride; Solutions; Swine; Time Factors; Viral Load; Virus Inactivation; Virus Replication | 2008 |
[Novel risk factors for cardiovascular disease and tobacco smoke].
Topics: Adult; Arginine; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Causality; Comorbidity; Environmental Monitoring; Epidemiological Monitoring; Fibrinogen; Homocysteine; Humans; Male; Middle Aged; Risk Factors; Smoking; Tobacco Smoke Pollution | 2008 |
Simultaneous use of argatroban and heparin during cardiopulmonary bypass.
Topics: Animals; Anticoagulants; Antithrombin III; Arginine; Blood Coagulation; Blood Platelets; Cardiopulmonary Bypass; Dogs; Drug Administration Schedule; Drug Therapy, Combination; Fibrinogen; Hemoglobins; Heparin; Infusions, Intravenous; Intraoperative Care; Pipecolic Acids; Sulfonamides; Thrombin | 2010 |
Arginine methylation in subunits of mammalian pre-mRNA cleavage factor I.
Topics: Animals; Arginine; Fibrinogen; Gene Expression; Mammals; Methylation; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases; RNA Precursors | 2010 |
Substitution (γ335Trp→Arg) in fibrinogen Fremantle causes diminished γ chain expression and increased sialic acid content.
Topics: Adult; Amino Acid Substitution; Arginine; Blood Coagulation; Blood Coagulation Disorders, Inherited; Female; Fibrinogen; Fibrinogens, Abnormal; Genetic Predisposition to Disease; Heredity; Humans; Middle Aged; Mutation; N-Acetylneuraminic Acid; Pedigree; Phenotype; Protein Conformation; Structure-Activity Relationship; Tryptophan | 2010 |
Increased nitric oxide production in platelets from severe chronic renal failure patients.
Topics: Adenosine Diphosphate; Arginine; Blood Platelets; Case-Control Studies; Collagen; Cyclic GMP; Female; Fibrinogen; Humans; Inflammation; Kidney Failure, Chronic; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Platelet Aggregation | 2011 |
Lipid-apheresis improves microcirculation of the upper limbs.
Topics: Adult; Aged; Arginine; Atrial Natriuretic Factor; Blood Component Removal; Blood Flow Velocity; Endothelin-1; Epinephrine; Erythrocyte Aggregation; Female; Fibrinogen; Hand; Humans; Hypercholesterolemia; Hyperlipoproteinemia Type II; Laser-Doppler Flowmetry; Lipids; Male; Microcirculation; Microscopic Angioscopy; Middle Aged; Norepinephrine; Photoplethysmography | 2011 |
Vascular endothelial function assessed by a noninvasive ultrasound method and serum asymmetric dimethylarginine concentrations in mild-to-moderate plaque-type psoriatic patients.
Topics: Acute-Phase Proteins; Adult; Arginine; C-Reactive Protein; Case-Control Studies; Endothelium, Vascular; Female; Fibrinogen; Humans; Male; Psoriasis; Severity of Illness Index; Ultrasonography; Vasodilation | 2011 |
Platelet activation, oxidative stress and overexpression of inducible nitric oxide synthase in moderate heart failure.
Topics: Adenosine Diphosphate; Arginine; Blood Platelets; C-Reactive Protein; Case-Control Studies; Collagen; Female; Fibrinogen; Heart Failure; Humans; Inflammation; Male; Middle Aged; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Platelet Activation; Platelet Aggregation; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2011 |
RGD mimetics containing phthalimidine fragment as novel ligands of fibrinogen receptor.
Topics: Arginine; Blood Platelets; Drug Design; Drug Evaluation, Preclinical; Fibrinogen; Fluorescein-5-isothiocyanate; Humans; Isoquinolines; Ligands; Oligopeptides; Phthalimides; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Receptors, Fibrinogen; Software; Stereoisomerism; Structure-Activity Relationship; Tirofiban; Tyrosine | 2011 |
Blood coagulation in fish.
Topics: Animals; Arginine; Blood Coagulation; Blood Coagulation Tests; Blood Platelets; Calcium; Fibrinogen; Fibrinolysis; Fishes; Humans; Plasma; Prothrombin; Species Specificity; Thrombin; Tosylarginine Methyl Ester | 1962 |
Designing allosteric regulators of thrombin. Monosulfated benzofuran dimers selectively interact with Arg173 of exosite 2 to induce inhibition.
Topics: Allosteric Regulation; Anticoagulants; Arginine; Arylsulfonates; Benzofurans; Binding Sites; Cell Line; Dimerization; Factor Xa Inhibitors; Fibrinogen; Heparin; Humans; Kinetics; Models, Molecular; Mutation; Protein Binding; Recombinant Proteins; Structure-Activity Relationship; Thrombin | 2012 |
Matrix-assisted laser desorption ionization-time of flight mass spectrometry identification of peptide citrullination site using Br signature.
Topics: Amino Acid Sequence; Animals; Arginine; Binding Sites; Bromine; Cattle; Citrulline; Fibrinogen; Glyoxal; Peptides; Serum Albumin, Bovine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2013 |
Concentration-dependent viscosity of binary and ternary mixtures of nonassociating proteins: measurement and analysis.
Topics: Animals; Arginine; Cattle; Chickens; Fibrinogen; Humans; Ovomucin; Serum Albumin, Bovine; Solutions; Viscosity | 2013 |
A novel fibrin(ogen)olytic trypsin-like protease from Chinese oak silkworm (Antheraea pernyi): purification and characterization.
Topics: Amino Acid Sequence; Animals; Arginine; China; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Esterases; Fibrin; Fibrinogen; Fibrinolysis; Insect Proteins; Kinetics; Mice; Molecular Sequence Data; Moths; Peptide Hydrolases; Phylogeny; Sequence Analysis, DNA; Sequence Analysis, Protein; Sequence Homology, Amino Acid; Substrate Specificity; Thrombosis; Trypsin | 2014 |
Mannose-binding lectin promotes local microvascular thrombosis after transient brain ischemia in mice.
Topics: Animals; Antithrombins; Arginine; Brain Ischemia; Cerebrovascular Circulation; Disease Models, Animal; Fibrinogen; Infarction, Middle Cerebral Artery; Magnetic Resonance Imaging; Male; Mannose-Binding Lectin; Mice; Mice, Inbred C57BL; Mice, Knockout; Microcirculation; Pipecolic Acids; Reperfusion Injury; Sulfonamides; Thrombosis | 2014 |
Relation of asymmetric dimethylarginine levels to macrovascular disease and inflammation markers in type 2 diabetic patients.
Topics: Aged; Arginine; Atherosclerosis; Biomarkers; Blood Sedimentation; C-Reactive Protein; Carotid Intima-Media Thickness; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Fibrinogen; Homocysteine; Humans; Inflammation Mediators; Male; Middle Aged; Regression Analysis; Systemic Vasculitis; Up-Regulation | 2014 |
A central role for intermolecular dityrosine cross-linking of fibrinogen in high molecular weight advanced oxidation protein product (AOPP) formation.
Topics: Advanced Oxidation Protein Products; Arginine; Blotting, Western; Cross-Linking Reagents; Dose-Response Relationship, Drug; Fibrinogen; Humans; Hypochlorous Acid; Lysine; Molecular Weight; Oxidation-Reduction; Protein Carbonylation; Serum Albumin; Tyrosine | 2015 |
Common FXIII and fibrinogen polymorphisms in abdominal aortic aneurysms.
Topics: Aged; Aged, 80 and over; Aortic Aneurysm, Abdominal; Arginine; Factor XIIIa; Fibrinogen; Genetic Association Studies; Humans; Middle Aged; Polymorphism, Single Nucleotide; White People | 2014 |
Ameliorative Effects of Curcumin on Fibrinogen-Like Protein-2 Gene Expression, Some Oxido-Inflammatory and Apoptotic Markers in a Rat Model of l-Arginine-Induced Acute Pancreatitis.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Arginine; Caspase 3; Curcumin; Disease Models, Animal; Fibrinogen; Gene Expression Regulation; Inflammation; Injections, Intraperitoneal; Male; Oxidative Stress; Pancreatitis, Acute Necrotizing; Peroxidase; Protein Carbonylation; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tumor Necrosis Factor-alpha | 2016 |
Dabigatran and Argatroban Diametrically Modulate Thrombin Exosite Function.
Topics: Allosteric Regulation; Antithrombins; Arginine; Binding Sites; Biocatalysis; Blood Coagulation; Catalytic Domain; Dabigatran; Fibrin; Fibrinogen; Humans; Pipecolic Acids; Protein Binding; Substrate Specificity; Sulfonamides; Surface Plasmon Resonance; Thrombin | 2016 |
Influences of argatroban on five fibrinogen assays.
Topics: Adult; Arginine; Blood Coagulation; Blood Coagulation Tests; Female; Fibrinogen; Humans; Male; Pipecolic Acids; Sulfonamides | 2017 |
Involvement of the Arg566 residue of Aeromonas sobria serine protease in substrate specificity.
Topics: Aeromonas; Amino Acid Sequence; Arginine; Bacterial Proteins; Fibrinogen; Humans; Kininogens; Molecular Chaperones; Mutagenesis, Site-Directed; Proteolysis; Serine Proteases; Substrate Specificity | 2017 |
Physico-chemical Changes Induced in the Serum Proteins Immunoglobulin G and Fibrinogen Mediated by Methylglyoxal.
Topics: Arginine; Benzothiazoles; Fibrinogen; Furaldehyde; Glycation End Products, Advanced; Glycosylation; Humans; Immunoglobulin G; Kinetics; Lysine; Malondialdehyde; Oxidation-Reduction; Protein Carbonylation; Pyruvaldehyde; Solutions; Spectrometry, Fluorescence | 2020 |
Analysis of L-arginine:glycine amidinotransferase-, creatine- and homoarginine-dependent gene regulation in the murine heart.
Topics: Amidinotransferases; Animals; Arginine; Connective Tissue Growth Factor; Creatine; Desmocollins; Disease Models, Animal; Energy Metabolism; Fibrinogen; Gene Expression Regulation; Genetic Association Studies; Homoarginine; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Mice, Transgenic; Myocardial Infarction; Myocardium; Potassium Channels; Transcriptome | 2020 |
Unexpectedly Low Fibrinogen.
Topics: Antithrombins; Arginine; Blood Chemical Analysis; Fibrinogen; Heparin; Humans; Male; Middle Aged; Pipecolic Acids; Sulfonamides; Thrombocytopenia | 2020 |
A conserved arginine residue in a staphylococcal anti-sigma factor is required to preserve its kinase activity, structure, and stability.
Topics: Adenosine Triphosphate; Arginine; Bacillus subtilis; Bacterial Proteins; Carrier Proteins; Fibrinogen; Gene Expression Regulation, Bacterial; Sigma Factor; Staphylococcus aureus | 2022 |
PAD4 Immunization Triggers Anti-Citrullinated Peptide Antibodies in Normal Mice: Analysis With Peptide Arrays.
Topics: Animals; Anti-Citrullinated Protein Antibodies; Arginine; Autoantibodies; Fibrinogen; Immunization; Immunoglobulin G; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Peptides; Protein-Arginine Deiminase Type 4; Vimentin | 2022 |
A Fibrinogen-Mimicking, Activated-Platelet-Sensitive Nanocoacervate Enhances Thrombus Targeting and Penetration of Tissue Plasminogen Activator for Effective Thrombolytic Therapy.
Topics: Animals; Arginine; Aspartic Acid; Chitosan; Fibrinogen; Fibrinolytic Agents; Glycine; Hemorrhage; Hemostatics; Mice; Oligopeptides; Thrombolytic Therapy; Thrombosis; Tissue Plasminogen Activator | 2022 |
Association of Asymmetric and Symmetric Dimethylarginine with Inflammation in the Population-Based Study of Health in Pomerania.
Topics: Arginine; Biomarkers; C-Reactive Protein; Cytokines; Fibrinogen; Humans; Inflammation | 2023 |