arginine has been researched along with etoposide in 240 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 91 (37.92) | 18.7374 |
| 1990's | 95 (39.58) | 18.2507 |
| 2000's | 37 (15.42) | 29.6817 |
| 2010's | 17 (7.08) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Komano, T; Morishima, M; Taguchi, Y; Ueda, K | 1 |
| Fisher, LM; Keller, BA; Patel, S | 1 |
| Futterweit, S; Mermelstein, A; Metzger, S; Pettei, M; Trachtman, H | 1 |
| Chen, T; Hébert, J; Li, E; Richard, S; Yu, Z | 1 |
| Baranek, T; Cornillet-Lefebvre, P; Eddabra, L; El Btaouri, H; Madoulet, C; Morjani, H; Wenner, T | 1 |
| Chiou, YY; Fu, SL; Lin, CH; Lin, WJ; Shih, IY; Weng, TH; Yang, JH | 1 |
| Chougule, MB; Haware, RV; Kim, SW; Nam, K; Turkson, J; Yang, R; Zou, Y; Zuo, YY | 1 |
| Amiel, JL; Hayat, M; Mathé, G; Pouillart, P; Schwarzenberg, L; Tubiana, M | 1 |
| Carter, SK; Slavik, M | 1 |
| Grieder, A; Maurer, R; Stähelin, H | 1 |
| Adamson, RH; Mead, JA; Sieber, SM | 1 |
| Carter, SK; Muggia, FM; Rozencweig, M; Slavik, M | 1 |
| Bunn, PA; Ihde, DC; Radice, PA | 1 |
| Henney, JE; Muggia, FM; Rozencweig, M; Von Hoff, DD | 1 |
| Crooke, ST; Gutierrez, ML | 1 |
| Allen, LM | 1 |
| Brewer, CF; Gensler, WJ; Horwitz, SB; Loike, JD; Sternlicht, H | 1 |
| Coulter, D; Kalish, R; Valeriote, FA; Vietti, TJ | 1 |
| Botkin, C; Knutsen, T; Sieber, SM; Whang-Peng, J | 1 |
| Allen, L | 1 |
| Barouh, M; Carpentier, Y; Cattan, A; Cattan, E; Pourny, C | 1 |
| Stähelin, H | 1 |
| Allen, LM; Creaven, PJ | 1 |
| Avery, T; Rivera, G; Roberts, DW | 1 |
| Beck, H; Capranico, G; Gazdar, AF; Giaccone, G; Zunino, F | 1 |
| Bergman, B; Sörenson, S; Sullivan, M | 1 |
| Kohn, KW; Orr, A; Pommier, Y; Riou, JF | 1 |
| Long, BH | 1 |
| Kohno, K; Kuwano, M; Matsuda, T; Matsuo, K; Takano, H | 1 |
| Constantinou, A; Grdina, D; Huberman, E; Kiguchi, K | 1 |
| Lorico, A; Rappa, G; Sartorelli, AC | 1 |
| Weiss, RB | 1 |
| D'Incalci, M; Garattini, S | 4 |
| Clark, PI | 1 |
| Ingargiola, GB; Pavone-Macaluso, M; Serretta, V | 1 |
| Hande, KR | 2 |
| Crist, WM; Crom, WR; Evans, WE; Groom, S; McLeod, HL; Relling, MV; Rivera, GK; Rodman, JH; Silverstein, K | 1 |
| Chapuis, JC; Keng, PC; Siemann, DW | 1 |
| Dass, C; Desiderio, DM; Evans, R; Nemec, J; Relling, MV | 1 |
| Busch, FW; Ehninger, G; Hiddemann, W; Jaschonek, K; Proksch, B; Schleyer, E; Schmidt, H; Schuler, U; Wanner, T | 1 |
| Eden, OB; Shaw, MP | 1 |
| Kohno, K; Kuwano, M; Takano, H | 1 |
| Bergman, B; Bork, E; Dombernowsky, P; Ersbøll, J; Hansen, HH; Hansen, M | 1 |
| Beck, WT; Danks, MK | 1 |
| Gewirtz, DA | 1 |
| Lihou, MG; Smith, PJ; Tomlinson, FH | 1 |
| Brattain, MG; Casazza, AM; Long, BH; Lorico, A; Wang, L; Wang, RC | 1 |
| Suciu, D | 1 |
| Derry, WB; Gupta, RS; Pamidi, CC | 1 |
| Leblanc, J; Sikorska, M; Smith, C; Walker, PR; Whitfield, JF; Youdale, T | 1 |
| Fujii, N; Kawada, S; Nakano, H; Yamashita, Y | 1 |
| Biron, P; Bouffet, E; Brunat-Mentigny, M; Chauvin, F; Ladenstein, R; Lasset, C; Philip, I; Philip, T | 1 |
| Chrétien, P; Huot, J; Lambert, H; Landry, J; Roy, G | 1 |
| Bertrand, R; Jenkin, J; Kerrigan, D; Pommier, Y; Sarang, M | 1 |
| Behm, FG; Evans, WE; Hancock, ML; Head, DR; Mahmoud, MH; Pui, CH; Raimondi, SC; Ribeiro, RC; Rivera, GK; Sandlund, JT | 1 |
| Shin, CG; Snapka, RM; Strayer, JM; Wani, MA | 1 |
| Muggia, FM; Russell, CA | 1 |
| Stähelin, HF; von Wartburg, A | 1 |
| Crist, WM; Crone, ME; Fairclough, DL; Kellie, SJ; Pui, CH; Rivera, GK; Rodman, JH | 1 |
| Butti, G; D'Incalci, M; Donelli, MG; Gaetani, P; Knerich, R; Rossi, C; Silvani, V; Zucchetti, M | 1 |
| Elinder, G; Henter, JI | 1 |
| Bugat, R; Canal, P; Chatelut, E; Chevreau, C; de Forni, M; Houin, G; Johnson, NP; Plusquellec, Y; Roche, H | 1 |
| Gupta, R | 1 |
| Elkind, MM; Shibuya, ML; Utsumi, H | 1 |
| Kiue, A; Kohno, K; Kuwano, M; Matsuo, K; Sato, S; Takano, H | 1 |
| De Boben, M; Diedrich, H; Freund, M; Ganser, A; Heil, G; Henke, M; Heyll, A; Hiddemann, W; Knauf, U; Koch, P | 1 |
| Björkholm, M | 1 |
| Friche, E; Hansen, HH; Jensen, PB; Roed, H; Skovsgaard, T; Spang-Thomsen, M; Vindeløv, L | 1 |
| D'Incalci, M; Figoli, F; Montaldo, PG; Sorio, R; Tirelli, U; Zanette, ML; Zucchetti, M | 1 |
| Huang, L; White, JC; Wright, SE | 1 |
| Hines, LH; White, JC; Wright, SE | 1 |
| Bauters, F; Estienne, MH; Facon, T; Fenaux, P; Millot, F; Pagniez, D; Preud'homme, C; Vanhaesbroucke, C | 1 |
| Alexander, RB; Coffey, DS; Nelson, WG | 1 |
| Kotake, T; Matsuda, M; Miki, T; Seguchi, T | 1 |
| Coffman, FD; Godwin, A; Green, LM; Ware, CF | 1 |
| Davies, SL; Davies, SM; Harris, AL; Hickson, ID | 1 |
| Lönn, S; Lönn, U; Nylen, U; Winblad, G | 1 |
| Ellis, AL; Gewirtz, DA; Povirk, LF; Randolph, JK; Swerdlow, PS; Yalowich, JC; Yanovich, S | 1 |
| Martin, J; Nunn, AJ; Siddall, SJ | 1 |
| Kinouchi, T; Kotake, T; Kuroda, M; Maeda, O; Miki, T; Saiki, S; Tomooka, Y; Usami, M; Yoshimura, K | 1 |
| Bult, A; Holthuis, JJ; van Bennekom, WP; van der Horst, FA; van Opstal, MA | 1 |
| McVie, G; Muggia, FM | 1 |
| Powelson, MA; Snapka, RM; Strayer, JM | 1 |
| Beerman, TA; Sigmund, RD; Woynarowski, JM | 1 |
| Chow, KC; Macdonald, TL; Ross, WE | 1 |
| Berendsen, HH; Haaxma-Reiche, H; Postmus, PE | 1 |
| Evans, WE; Fonné-Pfister, R; Meyer, UA; Relling, MV | 1 |
| Liu, LF; Rowe, TC; Yang, L | 1 |
| Haim, N; Nemec, J; Roman, J; Sinha, BK | 1 |
| Brattain, MG; Long, BH; Musial, ST | 3 |
| White, JC; Wright, SE | 1 |
| Lönn, S; Lönn, U | 1 |
| Alexander, RB; Coffey, DS; Isaacs, JT | 1 |
| Kerrigan, D; Kohn, KW; Pommier, Y | 1 |
| Holthuis, JJ | 1 |
| Dombernowsky, P; Hansen, HH | 1 |
| Bakkenist, TR; de Vries, J; Lankelma, J; Pinedo, HM; Retèl, J; van den Akker, E; Van Maanen, JM | 1 |
| Clark, PI; Slevin, ML | 1 |
| Beaujean, F; Behard, C; Benhamou, E; Deville, A; Flamant, F; Hartmann, O; Kalifa, C; Lejars, O; Patte, C; Thyss, A | 1 |
| Bromke, A; Bryant, DW; Gupta, R; Gupta, RS; McCalla, DR; Singh, B | 1 |
| Chenchaiah, PC; Gupta, R; Gupta, RS | 1 |
| Chenchaiah, PC; Gupta, RS | 1 |
| Canetta, R; Carbone, A; Tirelli, U; Veronesi, A; Zagonel, V | 1 |
| Amato, G; Broggini, M; Colombo, T; D'Incalci, M; Erba, E; Vaghi, M | 1 |
| Bugat, R; Canal, P; Carton, M; Michel, C; Soula, G | 1 |
| Bresson, ML; Cattan, A | 1 |
| Hiraoka, M; Nakanomyo, H; Shiraya, M | 1 |
| Christensen, IJ; Hansen, HH; Roed, H; Spang-Thomsen, M; Vindelov, LL | 1 |
| Hines, LH; Rathmell, JP; White, JC | 1 |
| Bodey, GP; Brown, NS; Ho, DH; Issell, BF; Kanellopoulos, KS | 1 |
| Chen, GL; Halligan, BD; Liu, LF; Rowe, TC; Tewey, KM; Yang, L | 1 |
| Glisson, B; Liu, L; Ross, W; Rowe, T; Yalowich, J | 1 |
| Kessinger, A | 1 |
| Schwarz, MA; Snyder, RD | 1 |
| Fry, DW; Goldman, ID; Yalowich, JC | 1 |
| Pawlicki, M; Zuchowska-Vogelgesang, B | 1 |
| Crom, WR; Evans, WE; Hutson, PR; Sinkule, JA; Stewart, CF; Yee, GC | 1 |
| Gahrton, G | 1 |
| Long, BH; Minocha, A | 1 |
| Płuzańska, A; Robak, T | 1 |
| Gasalla Chacón, R; Gónzalez Larriba, JL; Grande, C; Montero García, JM; Picaporte, MA | 1 |
| Lim, CK; Peters, TJ | 1 |
| Bellamy, AS; Hill, BT | 1 |
| Dow, LW; Evans, WE; Horvath, A; Look, AT; Sinkule, JA | 1 |
| Gupta, RS; Singh, B | 1 |
| Brinkman, UA; de Ruiter, C; de Vries, J; Frei, RW; Werkhoven-Goewie, CE | 1 |
| Alberts, DS; Dorr, RT | 1 |
| Evans, WE; Sinkule, JA | 1 |
| Canetta, R; D'Incalci, M; Franchin, G; Galligioni, E; Grigoletto, E; Rossi, C; Tirelli, U; Trovò, MG; Tumolo, S; Veronesi, A | 1 |
| Fuerst, ML | 1 |
| Gupta, RS | 1 |
| De Bruyne, GK; Dragonetti, CH; Mareel, MM; Van Cauwenberge, RM | 1 |
| Dombernowsky, P; Hansen, HH; Nissen, NI; Pedersen, AG | 1 |
| Loike, JD | 1 |
| Creaven, PJ | 1 |
| Issell, BF | 1 |
| Bedogni, P; Canetta, R; Florentine, S; Hilgard, P; Lenaz, L | 1 |
| Curry, ME; Issell, BF; Tihon, C | 1 |
| Crom, WR; Dow, L; Evans, WE; Look, AT; Rivera, G; Sinkule, JA | 1 |
| Allen, LM; Nordqvist, S; Okonmah, AD; Tejada, F | 1 |
| Colvin, M; Jardine, I; Strife, RJ | 2 |
| Bron, D; Carde, P; de Bock, R; De Wolf-Peeters, C; Delmer, A; Keunig, JJ; Keuning, JJ; Somers, R; Thomas, J; Tirelli, U | 1 |
| Bianco, AR; Bianco, C; Ciardiello, F; Damiano, V; Davies, SL; Harris, AL; Hickson, ID; North, PS; Pepe, S; Tortora, G | 1 |
| Alberto, P; Bacchi, M; Cerny, T; Hürny, C; Joss, RA; Leyvraz, S; Ludwig, C; Martinelli, G; Stahel, R; Thürlimann, B | 1 |
| Bijnens, L; Hagenbeek, A; Kluin-Nelemans, JC; Meerwaldt, JH; Noordijk, EM; Peeters, CD; Pittaluga, S; Somers, R; Teodorovic, I; van Glabbeke, M | 1 |
| Chung, IK; Gootz, TD; McGuirk, PR; Muller, MT; Spitzner, JR | 1 |
| Felix, CA; Hosler, MR; Lange, BJ; Masterson, M; Wilson, AE; Winick, NJ | 1 |
| Gromova, II; Razin, SV; Thomsen, B | 1 |
| Ettinger, DS | 1 |
| Cowan, KH; Horton, JK; Nakagawa, M; Schneider, E; Yang, CH | 1 |
| Castel, V; Esquembre, C; Ferrís, J; Lopez-Andrew, JA; Senent, ML; Verdeguer, A | 1 |
| Muggia, FM | 1 |
| Beck, WT; Chen, M; Kim, R | 1 |
| Joel, SP; Slevin, ML | 1 |
| Crist, WM; Pratt, CB; Pui, CH; Rivera, GK; Santana, VM | 1 |
| Burghouts, JT; Haaxma-Reiche, H; Postmus, PE; van der Graaf, WT | 1 |
| Clynes, M; Moran, E; Redmond, A | 1 |
| Gonzalez, FJ; Korzekwa, KR; Nemec, J; Relling, MV; Schuetz, EG; Schuetz, JD | 1 |
| Evans, WE; McLeod, HL | 1 |
| Inaba, M; Kawada, S; Mitsuhashi, J; Nakano, H | 1 |
| Goel, R; Green, RM; Grewaal, D; Mikhael, NZ; Montpetit, VA; Redmond, MD; Stewart, DJ | 1 |
| Kohno, K; Kuwano, M; Matsuo, K; Sato, S; Tanimura, H; Uchiumi, T; Yamada, Y | 1 |
| Gemba, K; Kiura, K; Matsumura, T; Moritaka, T; Ohnoshi, T; Segawa, Y; Shibayama, T; Tabata, M; Takigawa, N; Ueoka, H | 1 |
| Coffman, FD; Cohen, S; Fleisher, S; Fresa, KL; Georgoff, I; Ye, X | 1 |
| Hidaka, K; Hirohashi, Y; Hisatsugu, T; Kohno, K; Kuwano, M; Sato, S | 1 |
| Andoh, T; Aratani, Y; Koyama, H | 1 |
| Broeker, PL; Pomykala, H; Rowley, JD; Super, HG; Tanabe, S; Thirman, MJ; Yonebayashi, Y; Zeleznik-Le, N | 1 |
| Campling, BG; Jain, N; Lam, YM; Pym, J | 1 |
| Frei, H; Würgler, FE | 1 |
| Abe, T; Hisano, T; Kohno, K; Koike, K; Kubo, T; Kuwano, M; Wada, M | 1 |
| Herngren, L; Liliemark, E; Liliemark, J; Peterson, C; Pettersson, B | 1 |
| Levac, P; Moss, T | 1 |
| Flavell, RA; Lorico, A; Rappa, G; Sartorelli, AC | 1 |
| Furukawa, M; Harada, T; Kuwano, M; Tanaka, T | 1 |
| Grillot, DA; Nuñez, G; Simonian, PL | 1 |
| Cellerino, R; Cetto, G; Graziano, F; Isidori, P; Mari, D; Pasini, F; Santo, A; Tummarello, D | 1 |
| Imbert, TF | 1 |
| Holm, B; Jensen, PB; Sehested, M | 1 |
| Bianco, C; Ciardiello, F; Damiano, V; Davies, SL; di Isernia, G; Harris, AL; Hickson, ID; North, P; Pepe, S; Tortora, G | 1 |
| Beck, WT; Mo, YY | 1 |
| Armato, U; Chiarini, A; Dal Pra, I; Whitfield, JF | 1 |
| Baas, F; Borst, P; de Haas, M; de Vree, JM; Elferink, RP; Jansen, G; Kool, M; Peters, GJ; Ponne, N; Scheffer, GL; Scheper, RJ; Smith, AJ; van der Linden, M | 1 |
| Jin, X; Liu, Z; Luo, B; Yin, L; Zeng, P | 1 |
| Bruzzese, N; Cittadini, A; Covacci, V; Ganapathi, R; Sgambato, A; Wolf, FI | 1 |
| Estlin, EJ; Hall, AG; Lowis, SP | 1 |
| Huismans, DR; Pieters, R; Schuurhuis, GJ; Styczynski, J; Veerman, AJ; Wysocki, M | 1 |
| Castro, MA; del Corral, JM; Feliciano, AS; Gordaliza, M | 1 |
| Belani, CP; Calvo, AR | 1 |
| Chen, S; Lu, D; Ren, H | 1 |
| Hsieh, TS; Hu, T; Liu, LF; Mao, Y; Wang, H; Zhou, N | 1 |
| Dingemans, AC; Giaccone, G; Postmus, PE; Scagliotti, GV; Span, S; van Ark-Otte, J; van der Valk, P | 1 |
| Boller, YC; Brandes, LM; Kennedy, KA; Lin, ZP; Patierno, SR; Russell, RL | 1 |
| Fezoui, H; Genet, P; Lionnet, F; Louvel, D; Pulik, M; Touahri, T | 1 |
| Stephenson, J | 1 |
| Barbui, T; Bassan, R; Carter, M; Casula, P; Di Bona, E; Fabris, P; Lambertenghi-Deliliers, G; Lerede, T; Lister, TA; Morandi, S; Pogliani, E; Rambaldi, A; Rohatiner, AZ; Rossi, G | 1 |
| Belinsky, MG; Chen, ZS; Kruh, GD; Shchaveleva, I; Zeng, H | 1 |
| Crocci, AJ; Lopes, LF; Minicucci, EM | 1 |
| Fan, Y; Huang, ZY; Sun, L; Zhang, YP | 1 |
| Bunn, PA; Simon, GR | 1 |
| Antoneli, CB; Arias, V; Chojniak, MM; de Camargo, B; de Cássia Braga Ribeiro, K; Novaes, PE; Steinhorst, F | 1 |
| Chen, XQ; He, YJ; Lin, TY; Liu, DG; Su, YS; Sun, XF | 1 |
| Castro, MA; del Corral, JM; García, PA; Gómez-Zurita, MA; Gordaliza, M | 1 |
| Blair, IA; Felix, CA; Zheng, N; Zhuo, X | 1 |
| Gruger, T; Heisig, P; Maxwell, A; Nitiss, JL; Pommier, Y; Seeber, S; Strumberg, D; Zechiedrich, EL | 1 |
| Bouvet, N; Ellershaw, C; Flamant, F; Habrand, JL; Marsden, HB; Martelli, H; Oberlin, O; Rey, A; Sanchez de Toledo, J; Spicer, RD; Spooner, D; Stevens, MC; Terrier-Lacombe, MJ; van Unnik, A | 1 |
| Seiter, K | 1 |
| Oberlin, O; Orbach, D; Quintana, E; Rey, A; Sanchez de Toledo, J; Stevens, MC; Terrier-Lacombe, MJ; van Unnik, A | 1 |
| Campana, D; Cheng, C; Downing, JR; Evans, WE; Hijiya, N; Howard, SC; Hudson, M; Jeha, S; Pei, D; Pui, CH; Razzouk, BI; Relling, MV; Ribeiro, RC; Rubnitz, JE; Sandlund, JT | 1 |
| Antoneli, CB; Arias, V; Castilho, MS; Chojniak, MM; de Aguirre Neto, JC; Novaes, PE; Ribeiro, KB | 1 |
| Feun, LG; Heros, D; Herrera, C; Landy, H; Marini, A; Markoe, A; Robles, C; Savaraj, N | 1 |
| Antoneli, CB; Arias, VA; Chojniak, MM; Malogolowkin, M; Novaes, PE; Ribeiro, KB; Rodriguez-Galindo, C; Soares, FA | 1 |
| Marik, PE; Vahid, B | 1 |
| Brassesco, MS; Camparoto, ML; Gras, DE; Martinez-Rossi, NM; Montaldi, AP; Sakamoto-Hojo, ET; Scrideli, CA; Tone, LG | 1 |
| Lv, M; Tian, X; Xu, H | 1 |
| Guan, T; Lin, X; Tang, X; Wang, J; Xu, H; Zhang, Y | 1 |
| Qiao, W; Wang, C; Wang, T; Xing, Y; Zhao, J | 1 |
| Arslan, AD; Beck, WT; Chen, CF; He, X; Mo, YY; Pommier, Y; Reinhold, WC | 1 |
| Lv, M; Xu, H | 1 |
| Brown, JB; Kadoyama, K; Kuwahara, A; Okuno, Y; Sakaeda, T; Yamamori, M | 1 |
| Ma, X; Ren, C; Sheng, Z; Wang, B; Xia, B; Zhang, W | 1 |
| Cao, X; Chen, Y; Duan, Y; Han, J; Hu, W; Jiang, M; Li, X; Liu, M; Liu, X; Ma, X; Shui, Y; Wang, Q; Zhang, L | 1 |
| Chen, Y; Duan, Y; Han, J; Jiang, XC; Li, X; Liu, M; Ma, X; Qin, S; Wang, Q; Xiang, R; Yu, Y; Zhang, L; Zhu, Y | 1 |
| Hu, Y; Liao, JX; Liu, H; Sun, JS; Tu, YH | 1 |
| Al-Rubai, AJ; Grabowska, AM; Ivanov, DP; Pratten, MK | 1 |
| Jakobs, A; Klempnauer, KH; Yusenko, M | 1 |
54 review(s) available for arginine and etoposide
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Investigational drugs under study by the United States National Cancer Institute.
Topics: Acrylates; Alkylating Agents; Ancitabine; Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Azacitidine; Chemical Phenomena; Chemistry; Chromomycins; Cisplatin; DNA, Neoplasm; Drug Evaluation, Preclinical; Etoposide; Humans; Ifosfamide; Leukemia L1210; Mice; Mitosis; National Institutes of Health (U.S.); Neoplasms; Neoplasms, Experimental; Razoxane; Tegafur; Teniposide; United States | 1976 |
Pharmacology of antitumor agents from higher plants.
Topics: Animals; Antineoplastic Agents, Phytogenic; Aporphines; Camptothecin; Carcinoma, Squamous Cell; Chemical Phenomena; Chemistry; Etoposide; Humans; Leukemia L1210; Leukemia, Experimental; Leukemia, Lymphoid; Maytansine; Melanoma; Naphthoquinones; Nasopharyngeal Neoplasms; Neoplasms; Neoplasms, Experimental; Phenanthrenes; Structure-Activity Relationship; Teniposide; Vinblastine; Vincristine | 1976 |
VM 26 and VP 16-213: a comparative analysis.
Topics: Animals; Brain Neoplasms; Drug Evaluation; Etoposide; Humans; Kinetics; Leukemia; Lung Neoplasms; Lymphoma; Neoplasms, Experimental; Podophyllotoxin; Teniposide; Urinary Bladder Neoplasms | 1977 |
Pediatric cancer chemotherapy: an updated review. I. Cis-Diammine--dichloroplatinum II (cisplatin), VM-26 (teniposide), VP-16 (etoposide), mitomycin C.
Topics: Child; Cisplatin; Clinical Trials as Topic; Drug Administration Schedule; Etoposide; Humans; Leukemia; Mitomycins; Neoplasms; Podophyllotoxin; Teniposide | 1979 |
Mechanisms of action of teniposide (VM-26) and comparison with etoposide (VP-16).
Topics: Antineoplastic Agents; DNA Damage; DNA Topoisomerases, Type II; Etoposide; Teniposide; Topoisomerase II Inhibitors | 1992 |
DNA topoisomerase-targeting antitumor agents and drug resistance.
Topics: Antineoplastic Agents; Camptothecin; DNA Topoisomerases, Type I; Drug Resistance; Etoposide; Humans; Teniposide; Tumor Cells, Cultured | 1992 |
Hypersensitivity reactions.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Asparaginase; Aziridines; Benzoquinones; Bleomycin; Chlorambucil; Cisplatin; Cyclophosphamide; Cytarabine; Dacarbazine; Drug Hypersensitivity; Etoposide; Fluorouracil; Humans; Ifosfamide; Melphalan; Methotrexate; Mitomycins; Neoplasms; Paclitaxel; Pentostatin; Procarbazine; Teniposide | 1992 |
Podophyllotoxin derivatives.
Topics: Animals; Drug Interactions; Drug Resistance; Etoposide; Humans; Teniposide | 1992 |
Clinical pharmacology and schedule dependency of the podophyllotoxin derivatives.
Topics: Chemical Phenomena; Chemistry, Physical; Drug Administration Schedule; Etoposide; Humans; Teniposide; Tissue Distribution | 1992 |
The role of epipodophyllotoxin derivatives in bladder cancer.
Topics: Combined Modality Therapy; Etoposide; Humans; Remission Induction; Teniposide; Urinary Bladder Neoplasms | 1992 |
Antitumor antibiotics, epipodophyllotoxins, and vinca alkaloids.
Topics: Animals; Antibiotics, Antineoplastic; Drug Interactions; Etoposide; Humans; Teniposide; Vinca Alkaloids | 1992 |
Disposition of antineoplastic agents in the very young child.
Topics: Age Factors; Antineoplastic Agents; Blood Proteins; Child; Child, Preschool; Doxorubicin; Etoposide; Humans; Infant; Infant, Newborn; Liver; Mercaptopurine; Methotrexate; Neoplasms; Nervous System; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Teniposide | 1992 |
[Mechanisms of resistance to DNA topoisomerase II inhibitors].
Topics: Animals; Cell Division; Cytotoxicity, Immunologic; Drug Resistance; Etoposide; Teniposide; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 1991 |
Mechanisms of resistance to drugs that inhibit DNA topoisomerases.
Topics: Amsacrine; Animals; Antineoplastic Agents; Camptothecin; Cricetinae; Daunorubicin; DNA Replication; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Doxorubicin; Drug Resistance; Etoposide; Humans; Mice; Teniposide; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors | 1991 |
Does bulk damage to DNA explain the cytostatic and cytotoxic effects of topoisomerase II inhibitors?
Topics: Amsacrine; Animals; Antineoplastic Agents; Cell Division; Cell Line; Cell Survival; DNA; DNA Damage; Etoposide; Humans; Teniposide; Topoisomerase II Inhibitors | 1991 |
Podophyllotoxin derivatives.
Topics: Animals; Drug Interactions; Drug Resistance; Etoposide; Humans; Neoplasms; Teniposide | 1991 |
New chemotherapies for ovarian cancer. Systemic and intraperitoneal podophyllotoxins.
Topics: Combined Modality Therapy; Etoposide; Female; Humans; Injections, Intraperitoneal; Ovarian Neoplasms; Teniposide | 1991 |
The chemical and biological route from podophyllotoxin glucoside to etoposide: ninth Cain memorial Award lecture.
Topics: Aldehydes; Antineoplastic Agents; Cell Division; Cyclosporins; Etoposide; Glucosides; Growth Inhibitors; History, 19th Century; History, 20th Century; Plants, Medicinal; Plants, Toxic; Podophyllotoxin; Podophyllum; Structure-Activity Relationship; Teniposide | 1991 |
Etoposide and teniposide in the treatment of acute leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Etoposide; Humans; Leukemia, Myeloid, Acute; Podophyllotoxin; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Teniposide | 1990 |
Etoposide and teniposide. Bioanalysis, metabolism and clinical pharmacokinetics.
Topics: Etoposide; Humans; Podophyllotoxin; Teniposide | 1988 |
The epipodophyllotoxin derivatives VM26 and VP16: experimental and clinical aspects.
Topics: Animals; Antineoplastic Agents; Etoposide; Humans; Podophyllotoxin; Teniposide | 1988 |
Podophyllotoxin derivatives VP-16 and VM-26.
Topics: Animals; Drug Resistance; Etoposide; Humans; Molecular Structure; Podophyllotoxin; Teniposide | 1988 |
Podophyllotoxin derivatives VP-16 and VM-26.
Topics: Animals; Cell Survival; Drug Interactions; Drug Resistance; Etoposide; Humans; Podophyllotoxin; Teniposide | 1987 |
The clinical pharmacology of etoposide and teniposide.
Topics: Chemical Phenomena; Chemistry; Drug Stability; Etoposide; Humans; Kidney; Kinetics; Liver; Podophyllotoxin; Teniposide | 1987 |
High dose chemotherapy with autologous bone marrow rescue for high grade gliomas of the brain: a potential for improvement in therapeutic results.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Brain Neoplasms; Carmustine; Combined Modality Therapy; Etoposide; Glioblastoma; Glioma; Humans; Lomustine; Teniposide | 1984 |
[New antineoplastic agents, their value and use].
Topics: Aminacrine; Antineoplastic Agents; Aspartic Acid; Cisplatin; Etoposide; Humans; Ifosfamide; Interferons; Medroxyprogesterone; Medroxyprogesterone Acetate; Methyltestosterone; Neoplasms; Phosphonoacetic Acid; Razoxane; Tamoxifen; Teniposide; Vinca Alkaloids | 1982 |
Pharmacokinetics of anticancer drugs in children.
Topics: Aminoacridines; Amsacrine; Antibiotics, Antineoplastic; Antineoplastic Agents; Bleomycin; Child; Cyclophosphamide; Etoposide; Humans; Kinetics; Mercaptopurine; Methotrexate; Naphthacenes; Podophyllotoxin; Teniposide; Vinca Alkaloids | 1983 |
Treatment of acute leukemia--advances in chemotherapy, immunotherapy, and bone marrow transplantation.
Topics: Aclarubicin; Acute Disease; Adolescent; Adult; Age Factors; Aminoacridines; Amsacrine; Anthraquinones; Antibodies, Monoclonal; Azacitidine; Bone Marrow Transplantation; Child; Child, Preschool; Drug Administration Schedule; Etoposide; Humans; Ifosfamide; Immunotherapy; Infant; Interferons; Leukemia; Leukemia, Lymphoid; Liposomes; Middle Aged; Mitoxantrone; Naphthacenes; Prognosis; Teniposide; Transplantation, Homologous; Transplantation, Isogeneic; Vinblastine; Vindesine | 1983 |
The epipodophyllotoxin derivatives VM-26 and VP-16-213, 1976-1979, a review.
Topics: Animals; Antineoplastic Agents; Etoposide; Hodgkin Disease; Humans; Leukemia, Lymphoid; Lung Neoplasms; Podophyllotoxin; Teniposide | 1980 |
VP16-213 and podophyllotoxin. A study on the relationship between chemical structure and biological activity.
Topics: Animals; Chemical Phenomena; Chemistry; DNA; Etoposide; HeLa Cells; Humans; Microtubules; Molecular Conformation; Nucleosides; Podophyllotoxin; Structure-Activity Relationship; Teniposide | 1982 |
The clinical pharmacology of VM26 and VP16-213. A brief overview.
Topics: Biotransformation; Blood-Brain Barrier; Etoposide; Humans; Intestinal Absorption; Kinetics; Models, Biological; Podophyllotoxin; Teniposide; Tissue Distribution | 1982 |
The podophyllotoxin derivatives VP16-213 and VM26.
Topics: Animals; Chemical Phenomena; Chemistry; Drug Therapy, Combination; Etoposide; Humans; Neoplasms; Podophyllotoxin; Teniposide | 1982 |
Current development of podophyllotoxins.
Topics: Chemistry, Pharmaceutical; Drug Compounding; Drug Stability; Drug Synergism; Drug Therapy, Combination; Etoposide; Humans; Kinetics; Podophyllotoxin; Teniposide | 1982 |
The place of ifosfamide in chemotherapy of small cell lung cancer: the Eastern Cooperative Oncology Group experience and a selected literature update.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Ifosfamide; Lung Neoplasms; Salvage Therapy; Teniposide; Vincristine | 1995 |
Secondary acute promyelocytic leukemia in a child treated with epipodophyllotoxins.
Topics: Bone Neoplasms; Child; Etoposide; Humans; Leukemia, Promyelocytic, Acute; Male; Neoplasms, Second Primary; Pelvic Bones; Sarcoma, Ewing; Teniposide | 1994 |
Teniposide: overview of its therapeutic potential in adult cancers.
Topics: Acquired Immunodeficiency Syndrome; Adult; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Clinical Trials as Topic; Clinical Trials, Phase I as Topic; Etoposide; Female; Genital Neoplasms, Female; Hodgkin Disease; Humans; Leukemia; Lung Neoplasms; Lymphoma; Lymphoma, Non-Hodgkin; Neoplasms; Sarcoma, Kaposi; Teniposide | 1994 |
Novel actions of inhibitors of DNA topoisomerase II in drug-resistant tumor cells.
Topics: Animals; Antineoplastic Agents; Cell Line; Drug Resistance; Etoposide; Humans; Models, Biological; Teniposide; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 1994 |
Schedule-dependent topoisomerase II-inhibiting drugs.
Topics: Amsacrine; Antibiotics, Antineoplastic; Antineoplastic Agents; Cell Cycle; Clinical Trials, Phase I as Topic; DNA Repair; Drug Administration Schedule; Etoposide; Humans; Metabolic Clearance Rate; Neoplasms; Teniposide; Topoisomerase II Inhibitors | 1994 |
Epipodophyllotoxins in the treatment of childhood cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Cytarabine; Etoposide; Humans; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Neoplasms; Neoplasms, Second Primary; Neuroblastoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Teniposide | 1994 |
Clinical pharmacokinetics and pharmacodynamics of epipodophyllotoxins.
Topics: Antineoplastic Combined Chemotherapy Protocols; Drug Resistance; Etoposide; Humans; Leukemia; Neoplasms; Neoplasms, Second Primary; Teniposide; Topoisomerase II Inhibitors | 1993 |
[DNA topoisomerases targeting anticancer agents and mechanism for acquirement of drug resistance].
Topics: Antineoplastic Agents, Phytogenic; Camptothecin; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Drug Resistance, Neoplasm; Etoposide; Humans; Irinotecan; Mutation; Neoplasms; Teniposide; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 1997 |
Etoposide: four decades of development of a topoisomerase II inhibitor.
Topics: Administration, Oral; Anthracyclines; Antineoplastic Agents, Phytogenic; Etoposide; Humans; Mitoxantrone; Neoplasms; Technology, Pharmaceutical; Teniposide; Topoisomerase II Inhibitors | 1998 |
Optimizing antimetabolite-based chemotherapy for the treatment of childhood acute lymphoblastic leukaemia.
Topics: Antimetabolites, Antineoplastic; Child; Cytarabine; Drug Administration Schedule; Etoposide; Humans; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Teniposide; Thioguanine | 2000 |
DNA topoisomerase II inhibitors.
Topics: Amsacrine; Antineoplastic Agents; Carcinogens; Disease Models, Animal; Etoposide; Evidence-Based Medicine; Humans; Intestinal Absorption; Mitoxantrone; Neoplasms; Nucleic Acid Synthesis Inhibitors; Research Design; Risk Factors; Teniposide; Tissue Distribution; Topoisomerase II Inhibitors | 2000 |
Antitumor properties of podophyllotoxin and related compounds.
Topics: Antineoplastic Agents, Phytogenic; Antiviral Agents; Etoposide; Humans; Immunosuppressive Agents; Podophyllotoxin; Structure-Activity Relationship; Teniposide | 2000 |
Lung cancer: therapeutic options for stage IV and recurrent NSCLC.
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carboplatin; Carcinoma, Non-Small-Cell Lung; Cisplatin; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Combined Modality Therapy; Deoxycytidine; Docetaxel; Etoposide; Gemcitabine; Humans; Irinotecan; Lung Neoplasms; Multicenter Studies as Topic; Neoplasm Recurrence, Local; Paclitaxel; Prognosis; Randomized Controlled Trials as Topic; Risk Factors; Survival Rate; Taxoids; Teniposide; Treatment Outcome; Vinblastine; Vinorelbine | 2001 |
Taxanes in the treatment of advanced (stage III and IV) non-small cell lung cancer (NSCLC): recent developments.
Topics: Angiogenesis Inhibitors; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Clinical Trials as Topic; Combined Modality Therapy; Deoxycytidine; Docetaxel; Etoposide; Female; Gemcitabine; Humans; Lung Neoplasms; Male; Microtubules; Multicenter Studies as Topic; Neoadjuvant Therapy; Organoplatinum Compounds; Paclitaxel; Palliative Care; Podophyllotoxin; Randomized Controlled Trials as Topic; Salvage Therapy; Survival Analysis; Taxoids; Teniposide; Treatment Outcome; Vinblastine; Vinorelbine | 2003 |
Podophyllotoxin: distribution, sources, applications and new cytotoxic derivatives.
Topics: Cytotoxins; Etoposide; Lignans; Organophosphorus Compounds; Plants, Toxic; Podophyllotoxin; Teniposide; Tumor Cells, Cultured | 2004 |
Toxicity of the topoisomerase II inhibitors.
Topics: Antineoplastic Agents; Cardiovascular Diseases; Daunorubicin; Doxorubicin; Enzyme Inhibitors; Epirubicin; Etoposide; Humans; Idarubicin; Leukemia; Middle Aged; Mitoxantrone; Mucositis; Podophyllotoxin; Teniposide; Topoisomerase II Inhibitors; Vascular Diseases | 2005 |
Pulmonary complications of novel antineoplastic agents for solid tumors.
Topics: Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Antineoplastic Agents; Bevacizumab; Deoxycytidine; Doxorubicin; Epirubicin; Etoposide; Everolimus; Gemcitabine; Humans; Lung; Lung Diseases; Mitoxantrone; Neoplasms; Pneumonia; Pyrimidines; Risk Factors; Sirolimus; Teniposide; Trastuzumab | 2008 |
A review on hemisynthesis, biosynthesis, biological activities, mode of action, and structure-activity relationship of podophyllotoxins: 2003-2007.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Etoposide; Humans; Inhibitory Concentration 50; Organophosphorus Compounds; Podophyllotoxin; Structure-Activity Relationship; Teniposide | 2009 |
Recent advances in semisynthesis, biosynthesis, biological activities, mode of action, and structure-activity relationship of podophyllotoxins: an update (2008-2010).
Topics: Antineoplastic Agents, Phytogenic; Cell Survival; Drug Screening Assays, Antitumor; Etoposide; Humans; Organophosphorus Compounds; Podophyllotoxin; Structure-Activity Relationship; Teniposide | 2011 |
Intensified therapy followed by autologous stem-cell transplantation (ASCT) versus conventional therapy as first-line treatment of follicular lymphoma: a meta-analysis.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Dexamethasone; Disease-Free Survival; Doxorubicin; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Interferon alpha-2; Interferon-alpha; Lymphoma, Follicular; Male; Melphalan; Middle Aged; Neoplasms, Second Primary; Prednisone; Recombinant Proteins; Remission Induction; Survival Analysis; Teniposide; Transplantation, Autologous; Treatment Outcome; Vincristine; Whole-Body Irradiation | 2013 |
18 trial(s) available for arginine and etoposide
| Article | Year |
|---|---|
Therapeutic trials with VP-16-213 and VM-26: active agents in small cell lung cancer, non-Hodgkin's lymphomas, and other malignancies.
Topics: Alopecia; Carcinoma, Small Cell; Clinical Trials as Topic; Drug Evaluation; Etoposide; Humans; Leukemia; Leukopenia; Lung Neoplasms; Lymphoma; Podophyllotoxin; Teniposide | 1979 |
Pediatric cancer chemotherapy: an updated review. I. Cis-Diammine--dichloroplatinum II (cisplatin), VM-26 (teniposide), VP-16 (etoposide), mitomycin C.
Topics: Child; Cisplatin; Clinical Trials as Topic; Drug Administration Schedule; Etoposide; Humans; Leukemia; Mitomycins; Neoplasms; Podophyllotoxin; Teniposide | 1979 |
Teniposide and etoposide in previously untreated small-cell lung cancer: a randomized study.
Topics: Aged; Aged, 80 and over; Carcinoma, Small Cell; Drug Administration Schedule; Etoposide; Female; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Prospective Studies; Teniposide | 1991 |
A single center experience with bone marrow transplantation for high risk neuroblastoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carboplatin; Carmustine; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Female; France; Humans; Infant; Male; Neuroblastoma; Organoplatinum Compounds; Remission Induction; Reoperation; Survival Rate; Teniposide; Vincristine | 1991 |
Acute myeloid leukemia in children treated with epipodophyllotoxins for acute lymphoblastic leukemia.
Topics: Acute Disease; Adolescent; Child; Child, Preschool; Drug Administration Schedule; Etoposide; Humans; Leukemia, Myeloid; Neoplasms, Second Primary; Podophyllotoxin; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Risk Factors; Teniposide | 1991 |
Teniposide and cisplatin given by intraperitoneal administration: preclinical and phase I/pharmacokinetic studies.
Topics: Adult; Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Evaluation; Drug Synergism; Etoposide; Female; Humans; Injections, Intraperitoneal; Leukemia P388; Leukopenia; Male; Mice; Middle Aged; Peritoneal Neoplasms; Podophyllotoxin; Remission Induction; Teniposide | 1991 |
Treatment of relapsed acute lymphocytic leukemia in adults.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow Transplantation; Brain Neoplasms; Combined Modality Therapy; Cytarabine; Daunorubicin; Dexamethasone; Etoposide; Female; Germany, West; Humans; Ifosfamide; Leucovorin; Life Tables; Male; Methotrexate; Middle Aged; Multicenter Studies as Topic; Neoplasm Recurrence, Local; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Spinal Cord Neoplasms; Teniposide; Testicular Neoplasms; Vindesine | 1990 |
[New antineoplastic drugs of the podophyllotoxin derivative group].
Topics: Adult; Child; Clinical Trials as Topic; Etoposide; Female; Humans; Leukemia; Lung Neoplasms; Lymphoma; Neoplasms; Ovarian Neoplasms; Podophyllotoxin; Teniposide; Urinary Bladder Neoplasms | 1983 |
EORTC study of non-Hodgkin's lymphoma: phase III study comparing CHVmP-VB and ProMACE-MOPP in patients with stage II, III, and IV intermediate- and high-grade lymphoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Leucovorin; Life Tables; Lymphoma, Non-Hodgkin; Male; Mechlorethamine; Methotrexate; Middle Aged; Neoplasm Staging; Prednisone; Procarbazine; Remission Induction; Survival Analysis; Teniposide; Thrombocytopenia; Treatment Outcome; Vincristine | 1994 |
Quality versus quantity of life in the treatment of patients with advanced small-cell lung cancer? A randomized phase III comparison of weekly carboplatin and teniposide versus cisplatin, adriamycin, etoposide alternating with cyclophosphamide, methotrexa
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Palliative Care; Prospective Studies; Quality of Life; Surveys and Questionnaires; Survival Rate; Teniposide; Vincristine | 1995 |
Efficacy of four different regimens in 64 mantle-cell lymphoma cases: clinicopathologic comparison with 498 other non-Hodgkin's lymphoma subtypes. European Organization for the Research and Treatment of Cancer Lymphoma Cooperative Group.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Etoposide; Europe; Female; Humans; Interferon alpha-2; Interferon-alpha; Lymphoma, Non-Hodgkin; Male; Mechlorethamine; Methotrexate; Middle Aged; Prednisone; Procarbazine; Recombinant Proteins; Remission Induction; Survival Rate; Teniposide; Vincristine | 1995 |
The place of ifosfamide in chemotherapy of small cell lung cancer: the Eastern Cooperative Oncology Group experience and a selected literature update.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Ifosfamide; Lung Neoplasms; Salvage Therapy; Teniposide; Vincristine | 1995 |
A randomized, controlled phase III study of cyclophosphamide, doxorubicin, and vincristine with etoposide (CAV-E) or teniposide (CAV-T), followed by recombinant interferon-alpha maintenance therapy or observation, in small cell lung carcinoma patients wit
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Interferon alpha-2; Interferon-alpha; Lung Neoplasms; Male; Middle Aged; Recombinant Proteins; Survival Analysis; Teniposide; Treatment Outcome; Vincristine | 1997 |
[Teniposide and cisplatin compared with etoposide and cisplatin for treatment of small cell lung cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Teniposide; Treatment Outcome | 2002 |
Treatment of nonmetastatic rhabdomyosarcoma in childhood and adolescence: third study of the International Society of Paediatric Oncology--SIOP Malignant Mesenchymal Tumor 89.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; Child, Preschool; Dactinomycin; Disease-Free Survival; Drug Administration Schedule; Epirubicin; Etoposide; Female; Humans; Ifosfamide; Infant; Infant, Newborn; Male; Multivariate Analysis; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis; Rhabdomyosarcoma; Teniposide; Treatment Outcome; Vincristine | 2005 |
Soft tissue sarcoma or malignant mesenchymal tumors in the first year of life: experience of the International Society of Pediatric Oncology (SIOP) Malignant Mesenchymal Tumor Committee.
Topics: Age Factors; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclophosphamide; Dactinomycin; Doxorubicin; Epirubicin; Etoposide; Humans; Ifosfamide; Infant; Infant, Newborn; Neoplasm Metastasis; Neoplasm Recurrence, Local; Rhabdomyosarcoma; Sarcoma; Survival Analysis; Teniposide; Vincristine | 2005 |
Clinical trial of CPT-11 and VM-26/VP-16 for patients with recurrent malignant brain tumors.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin; Etoposide; Female; Glioma; Humans; Irinotecan; Magnetic Resonance Imaging; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Recurrence, Local; Teniposide; Tomography, X-Ray Computed | 2007 |
Predictive value of (18)F-FDG hybrid PET/CT for the clinical outcome in patients with non-Hodgkin's lymphoma prior to and after autologous stem cell transplantation.
Topics: Adolescent; Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carmustine; Child; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Dexamethasone; Disease-Free Survival; Doxorubicin; Etoposide; Female; Fluorodeoxyglucose F18; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Lymphoma, Non-Hodgkin; Male; Melphalan; Middle Aged; Peripheral Blood Stem Cell Transplantation; Positron-Emission Tomography; Predictive Value of Tests; Prednisolone; Prednisone; Proportional Hazards Models; Radiopharmaceuticals; Rituximab; Teniposide; Tomography, X-Ray Computed; Transplantation, Autologous; Treatment Outcome; Vincristine; Young Adult | 2010 |
170 other study(ies) available for arginine and etoposide
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Amino acid substitutions in the first transmembrane domain (TM1) of P-glycoprotein that alter substrate specificity.
Topics: Alanine; Arginine; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Membrane; Cells, Cultured; Colchicine; DNA Mutational Analysis; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Etoposide; Glycine; Histidine; Humans; Immunoblotting; Isoleucine; Leucine; Substrate Specificity; Vinblastine | 1997 |
Mutations at arg486 and glu571 in human topoisomerase IIalpha confer resistance to amsacrine: relevance for antitumor drug resistance in human cells.
Topics: Amsacrine; Antigens, Neoplasm; Antineoplastic Agents; Arginine; DNA; DNA Topoisomerases, Type II; DNA-Binding Proteins; Drug Resistance, Neoplasm; Etoposide; Glutamic Acid; Humans; Isoenzymes; Point Mutation; Saccharomyces cerevisiae; Tumor Cells, Cultured | 2000 |
Anti-apoptotic effect of L-arginine in cultured rat mesangial cells.
Topics: Animals; Apoptosis; Arginine; Cells, Cultured; Cisplatin; Cytokines; DNA; DNA Fragmentation; Dose-Response Relationship, Drug; Etoposide; Glomerular Mesangium; Hydrogen Peroxide; Rats | 2000 |
A mouse PRMT1 null allele defines an essential role for arginine methylation in genome maintenance and cell proliferation.
Topics: Adaptor Proteins, Signal Transducing; Alleles; Animals; Arginine; Cell Proliferation; DNA; DNA Damage; DNA Repair Enzymes; DNA-Binding Proteins; Down-Regulation; Embryo, Mammalian; Etoposide; Female; Fibroblasts; Genome; Genomic Instability; Interphase; Methylation; Mice; Mice, Inbred C57BL; Mitosis; MRE11 Homologue Protein; Protein-Arginine N-Methyltransferases; Rad51 Recombinase; Radiation, Ionizing; RNA-Binding Proteins | 2009 |
Arginine 482 to glycine mutation in ABCG2/BCRP increases etoposide transport and resistance to the drug in HEK-293 cells.
Topics: Antineoplastic Agents, Phytogenic; Arginine; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Drug Resistance, Neoplasm; Etoposide; Flow Cytometry; Glycine; HEK293 Cells; Humans; Neoplasm Proteins; Point Mutation; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Transfection | 2012 |
Arginine methylation of hnRNPK negatively modulates apoptosis upon DNA damage through local regulation of phosphorylation.
Topics: Apoptosis; Arginine; Caspase 3; Cell Line; DNA Damage; Etoposide; Heterogeneous-Nuclear Ribonucleoprotein K; Humans; Methylation; Mutation; Phosphorylation; Protein Kinase C-delta; Protein-Arginine N-Methyltransferases; Repressor Proteins; Ribonucleoproteins | 2014 |
Factorial Design Based Multivariate Modeling and Optimization of Tunable Bioresponsive Arginine Grafted Poly(cystaminebis(acrylamide)-diaminohexane) Polymeric Matrix Based Nanocarriers.
Topics: Acrylamide; Arginine; Benzofurans; Chemistry, Pharmaceutical; Drug Carriers; Etoposide; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Nanoparticles; Particle Size; Polymers | 2017 |
Non-Hodgkin's malignant lymphomata in adults: chemo-radiotherapy in stages III and IV.
Topics: Adult; Antineoplastic Agents; Azirines; Bleomycin; Cyclophosphamide; Daunorubicin; Etoposide; Female; Humans; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Prednisone; Procarbazine; Teniposide; Triethylenemelamine; Vinblastine; Vincristine | 1975 |
Comparative study of early effects of epipodophyllotoxin derivatives and other cytostatic agents on mastocytoma cultures.
Topics: Antineoplastic Agents; Bleomycin; Cell Division; Cell Line; Colchicine; Cytarabine; DNA, Neoplasm; Etoposide; Mast-Cell Sarcoma; Mechlorethamine; Mercaptopurine; Methotrexate; Mitosis; Neoplasm Proteins; Neoplasms, Experimental; Podophyllotoxin; Razoxane; RNA, Neoplasm; Teniposide; Vincristine; X-Rays | 1977 |
Overview of early and investigational chemotherapeutic agents in solid tumors.
Topics: Alkylating Agents; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Aziridines; Azo Compounds; Camptothecin; Cycloleucine; Etoposide; Floxuridine; Humans; Neoplasms; Nitrogen Mustard Compounds; Picolinic Acids; Platinum; Porfiromycin; Streptonigrin; Teniposide; Thiotepa; Tubercidin | 1976 |
Comparison of uptake and binding of two epipodophyllotoxin glucopyranosides, 4'-demethyl epipodophyllotoxin thenylidene-beta-D-glucoside and 4'-demethyl epipodophyllotoxin ethylidene-beta-D-glucoside, in the L1210 leukemia cell.
Topics: Animals; Binding Sites; Biological Transport; Cell Nucleus; Etoposide; Kinetics; Leukemia L1210; Mice; Mice, Inbred DBA; Podophyllotoxin; Teniposide; Thermodynamics; Vinblastine | 1978 |
Structure-activity study of the inhibition of microtubule assembly in vitro by podophyllotoxin and its congeners.
Topics: Animals; Etoposide; In Vitro Techniques; Magnetic Resonance Spectroscopy; Microtubules; Podophyllotoxin; Stereoisomerism; Structure-Activity Relationship; Teniposide; Tubulin | 1978 |
Kinetics of cytotoxicity of VM-26 and VP-16-213 on L1210 leukemia and hematopoietic stem cells.
Topics: Animals; Cell Survival; Colony-Forming Units Assay; Dose-Response Relationship, Drug; Etoposide; Hematopoietic Stem Cells; Leukemia L1210; Podophyllotoxin; Rats; Teniposide; Time Factors | 1978 |
Teratogenic and cytogenetic effects of some plant-derived antitumor agents (vincristine, colchicine, maytansine, VP-16-213 and VM-26) in mice.
Topics: Abnormalities, Drug-Induced; Animals; Antineoplastic Agents; Cells, Cultured; Chromosome Aberrations; Chromosomes; Colchicine; Etoposide; Female; Gestational Age; Maytansine; Mice; Pregnancy; Teniposide; Teratogens; Vincristine | 1978 |
The role of drug disposition kinetics on cellular transport of the antineoplastic agent VM-26.
Topics: Animals; Biological Transport, Active; Chemical Phenomena; Chemistry; Diffusion; Etoposide; Kinetics; Leukemia L1210; Mice; Models, Biological; Podophyllotoxin; Protein Binding; Serum Albumin; Teniposide | 1978 |
Antimetastasis effect of two derivatives of epiposophyllotoxin in mice.
Topics: Animals; Etoposide; Lung Neoplasms; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Podophyllotoxin; Solvents; Teniposide; Time Factors | 1976 |
Delayed toxicity of epipodophyllotoxin derivatives (VM 26 and VP 16-213), due to a local effect.
Topics: Animals; Dose-Response Relationship, Drug; Etoposide; Female; Injections, Intraperitoneal; Injections, Intravenous; Leukemia L1210; Liver; Lung; Male; Mice; Organ Size; Podophyllotoxin; Rats; Teniposide; Time Factors | 1976 |
Comparison of the human pharmacokinetics of VM-26 and VP-16, two antineoplastic epipodophyllotixin glucopyranoside derivatives.
Topics: Body Water; Etoposide; Humans; Metabolic Clearance Rate; Models, Biological; Neoplasms; Podophyllotoxin; Teniposide | 1975 |
Response of L1210 to combinations of cytosine arabinoside and VM-26 or VP16-213.
Topics: Animals; Cytarabine; Drug Therapy, Combination; Etoposide; Female; Leukemia L1210; Leukemia, Experimental; Mice; Podophyllotoxin; Pyrans; Teniposide | 1975 |
Multidrug sensitivity phenotype of human lung cancer cells associated with topoisomerase II expression.
Topics: Adenocarcinoma; Antineoplastic Agents; Blotting, Northern; Blotting, Southern; Camptothecin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cell Line; Cell Survival; Cisplatin; DNA Topoisomerases, Type II; DNA, Neoplasm; Doxorubicin; Drug Screening Assays, Antitumor; Etoposide; Fluorouracil; Humans; Lung Neoplasms; Phenotype; Restriction Mapping; RNA, Neoplasm; Teniposide | 1992 |
Quality of life during chemotherapy for small cell lung cancer. II. A longitudinal study of the EORTC Core Quality of Life Questionnaire and comparison with the Sickness Impact Profile.
Topics: Aged; Attitude to Health; Carcinoma, Small Cell; Etoposide; Follow-Up Studies; Humans; Longitudinal Studies; Lung Neoplasms; Neoplasm Staging; Probability; Quality of Life; Surveys and Questionnaires; Teniposide | 1992 |
Differential effects of amsacrine and epipodophyllotoxins on topoisomerase II cleavage in the human c-myc protooncogene.
Topics: Amsacrine; Animals; Base Sequence; Binding Sites; Carcinoma, Small Cell; Cell Line; DNA Damage; DNA Topoisomerases, Type II; DNA, Neoplasm; Etoposide; Genes, myc; Humans; Leukemia L1210; Lung Neoplasms; Mice; Molecular Sequence Data; Promoter Regions, Genetic; Restriction Mapping; Substrate Specificity; Teniposide | 1992 |
The effect of topoisomerase inhibitors on the expression of differentiation markers and cell cycle progression in human K-562 leukemia cells.
Topics: Amsacrine; Aphidicolin; Cell Cycle; Cell Differentiation; Cycloheximide; Deoxyadenosines; Dose-Response Relationship, Drug; Etoposide; G2 Phase; Hemoglobins; Humans; Kinetics; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Melanins; Mitosis; Novobiocin; Teniposide; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 1992 |
Potentiation by novobiocin of the cytotoxic activity of etoposide (VP-16) and teniposide (VM-26).
Topics: Adenocarcinoma; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cell Survival; DNA; DNA Topoisomerases, Type II; Drug Synergism; Etoposide; Humans; Leukemia; Lung Neoplasms; Novobiocin; RNA; Teniposide; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 1992 |
Activity of etoposide (VP-16) and teniposide (VM-26) in exponential and plateau phase human tumor cell cultures.
Topics: Autoradiography; Carcinoma, Squamous Cell; Cell Line; Etoposide; Flow Cytometry; Humans; Teniposide; Thymidine; Tumor Cells, Cultured | 1992 |
Human cytochrome P450 metabolism of teniposide and etoposide.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Etoposide; Female; Humans; Infant; Kinetics; Liver Diseases; Male; Microsomes, Liver; Middle Aged; Teniposide | 1992 |
Intracellular cytosine arabinoside accumulation and cytosine arabinoside triphosphate formation in leukemic blast cells is inhibited by etoposide and teniposide.
Topics: Acute Disease; Adult; Aged; Amsacrine; Arabinofuranosylcytosine Triphosphate; Cytarabine; Drug Interactions; Etoposide; Humans; Leukemia; Middle Aged; Neoplastic Stem Cells; Phosphorylation; Teniposide; Tumor Cells, Cultured | 1992 |
Chemotherapy for pancreaticoblastoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Child, Preschool; Cisplatin; Cyclophosphamide; Dexamethasone; Doxorubicin; Etoposide; Humans; Male; Pancreatic Neoplasms; Teniposide; Vincristine | 1992 |
Comparison of in vitro activity of epipodophyllotoxins with other chemotherapeutic agents in human medulloblastomas.
Topics: Alkylating Agents; Amsacrine; Cell Division; Cell Survival; Cross-Linking Reagents; Cytarabine; DNA Damage; DNA Topoisomerases, Type II; Drug Resistance; Etoposide; Humans; Hydroxyurea; In Vitro Techniques; Karyotyping; Medulloblastoma; Teniposide; Tumor Cells, Cultured; Vincristine | 1991 |
Mechanisms of resistance to etoposide and teniposide in acquired resistant human colon and lung carcinoma cell lines.
Topics: Adenocarcinoma; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Cell Line; Colonic Neoplasms; DNA; DNA Damage; DNA Probes; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; Etoposide; Humans; Immunoblotting; Lung Neoplasms; Membrane Glycoproteins; Molecular Sequence Data; Neoplasm Proteins; Porfiromycin; RNA; Teniposide | 1991 |
Reproductive death of Chinese hamster V79 cells after exposure to chemical inhibitors of DNA synthesis.
Topics: 4-Nitroquinoline-1-oxide; Amsacrine; Animals; Benzamides; Bisbenzimidazole; Cell Division; Cell Line; Cisplatin; Cricetinae; Cricetulus; Cycloheximide; DNA Replication; Etoposide; Gene Expression Regulation; In Vitro Techniques; Kinetics; Methylnitronitrosoguanidine; Puromycin; Teniposide; Transcription, Genetic; Uracil | 1991 |
[Isolation of drug-resistant mutant cells].
Topics: Alkylating Agents; Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Aphidicolin; Camptothecin; Cell Separation; Drug Resistance; Etoposide; Humans; Hydroxamic Acids; Lovastatin; Monensin; Nucleic Acids; Teniposide; Toxins, Biological; Tunicamycin | 1991 |
Synthesis and biological activity of galactopyranoside derivatives of 4'-demethylepipodophyllotoxin showing VP-16 (etoposide)-like activity.
Topics: Acetals; Animals; Antineoplastic Agents; CHO Cells; Cricetinae; DNA; DNA Damage; Etoposide; Galactose; Podophyllotoxin; Structure-Activity Relationship; Teniposide | 1991 |
Topoisomerase II-reactive chemotherapeutic drugs induce apoptosis in thymocytes.
Topics: Amsacrine; Animals; Cycloheximide; Dactinomycin; Dexamethasone; DNA; Electrophoresis; Etoposide; Flow Cytometry; Lymphocytes; Mitosis; Rats; Rats, Inbred Strains; Teniposide; Thymus Gland; Time Factors; Topoisomerase II Inhibitors | 1991 |
Induction of a heat-stable topoisomerase II-DNA cleavable complex by nonintercalative terpenoides, terpentecin and clerocidin.
Topics: Anti-Bacterial Agents; Diterpenes; DNA; DNA Topoisomerases, Type II; Enzyme Induction; Etoposide; Hot Temperature; Teniposide | 1991 |
Increased survival after treatments with anticancer agents of Chinese hamster cells expressing the human Mr 27,000 heat shock protein.
Topics: Animals; Antineoplastic Agents; Arsenic; Arsenites; Blotting, Western; Carmustine; Cell Line; Cell Survival; Colchicine; Cricetinae; Dactinomycin; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; Etoposide; Fluorouracil; Heat-Shock Proteins; Humans; Hydrogen Peroxide; Pentosyltransferases; Sodium Compounds; Teniposide; Vincristine | 1991 |
Differential induction of secondary DNA fragmentation by topoisomerase II inhibitors in human tumor cell lines with amplified c-myc expression.
Topics: Adenocarcinoma; Colonic Neoplasms; DNA Damage; DNA Repair; DNA, Neoplasm; Etoposide; Gene Amplification; Genes, myc; Humans; Leukemia, Promyelocytic, Acute; Teniposide; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1991 |
Rapid evaluation of topoisomerase inhibitors: caffeine inhibition of topoisomerases in vivo.
Topics: Animals; Caffeine; Camptothecin; Etoposide; Haplorhini; Teniposide; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors | 1990 |
Hypersensitivity reactions to epipodophyllotoxins in children with acute lymphoblastic leukemia.
Topics: Adolescent; Adrenal Cortex Hormones; Antineoplastic Combined Chemotherapy Protocols; Bronchial Spasm; Child; Child, Preschool; Cyanosis; Diphenhydramine; Dose-Response Relationship, Drug; Drug Hypersensitivity; Etoposide; Female; Humans; Hypotension; Infant; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Premedication; Teniposide | 1991 |
Concentrations of VP16 and VM26 in human brain tumors.
Topics: Adult; Aged; Brain; Brain Neoplasms; Chromatography, High Pressure Liquid; Etoposide; Female; Humans; Male; Middle Aged; Teniposide; Tissue Distribution | 1991 |
Familial hemophagocytic lymphohistiocytosis. Clinical review based on the findings in seven children.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Child, Preschool; Combined Modality Therapy; Etoposide; Exchange Transfusion, Whole Blood; Female; Glucocorticoids; Histiocytosis, Non-Langerhans-Cell; Humans; Immunization, Passive; Infant; Male; Methotrexate; Plasmapheresis; Spleen; Teniposide | 1991 |
Tests for the genotoxicity of m-AMSA, etoposide, teniposide and ellipticine in Neurospora crassa.
Topics: Alkaloids; Amsacrine; Ellipticines; Etoposide; Molecular Structure; Mutagenicity Tests; Mutagens; Neurospora crassa; Podophyllotoxin; Teniposide | 1990 |
Novobiocin inhibits the repair of potentially lethal damage but not the repair of sublethal damage.
Topics: Amsacrine; Animals; Cell Line; Cricetinae; DNA Damage; DNA Repair; Etoposide; Novobiocin; Teniposide; Topoisomerase II Inhibitors | 1990 |
Reduction of drug accumulation and DNA topoisomerase II activity in acquired teniposide-resistant human cancer KB cell lines.
Topics: DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Drug Resistance; Etoposide; Humans; KB Cells; Podophyllotoxin; Temperature; Teniposide | 1990 |
Antitumor activity of the two epipodophyllotoxin derivatives VP-16 and VM-26 in preclinical systems: a comparison of in vitro and in vivo drug evaluation.
Topics: Animals; Drug Evaluation; Drug Resistance; Etoposide; Male; Mice; Mice, Inbred DBA; Neoplasms, Experimental; Teniposide; Tumor Stem Cell Assay | 1990 |
Pharmacokinetics of intrapleural versus intravenous etoposide (VP 16) and teniposide (VM 26) in patients with malignant pleural effusion.
Topics: Aged; Etoposide; Female; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Pleural Effusion; Podophyllotoxin; Teniposide | 1990 |
Partitioning of teniposide into membranes and the role of lipid composition.
Topics: Etoposide; Kinetics; Lipid Bilayers; Models, Biological; Phosphatidylcholines; Podophyllotoxin; Structure-Activity Relationship; Teniposide; Tritium | 1990 |
Effects of the lipophilic anticancer drug teniposide (VM-26) on membrane transport.
Topics: Amino Acids; Animals; Biological Transport; Carcinoma, Ehrlich Tumor; Carrier Proteins; Cell Membrane; Cell Membrane Permeability; Cytarabine; Etoposide; Humans; Membrane Lipids; Membranes, Artificial; Nucleosides; Podophyllotoxin; Teniposide; Tumor Cells, Cultured | 1990 |
Acute monocytic leukaemia in adults: treatment and prognosis in 99 cases.
Topics: Adolescent; Adult; Aged; Aminacrine; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia, Monocytic, Acute; Male; Middle Aged; Prognosis; Teniposide | 1990 |
Synergistic enhancement by tumor necrosis factor of in vitro cytotoxicity from chemotherapeutic drugs targeted at DNA topoisomerase II.
Topics: Animals; Bleomycin; Cell Line; Cell Survival; Cytarabine; Dactinomycin; DNA Topoisomerases, Type II; Doxorubicin; Drug Synergism; Etoposide; Fibrosarcoma; Glycoproteins; Hydroxyurea; Mice; Recombinant Proteins; Teniposide; Tumor Necrosis Factor-alpha | 1987 |
[Multidisciplinary treatment of advanced testicular tumors].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Combined Modality Therapy; Etoposide; Humans; Male; Middle Aged; Organoplatinum Compounds; Prognosis; Teniposide; Testicular Neoplasms; Vinblastine | 1989 |
Cytotoxicity mediated by tumor necrosis factor in variant subclones of the ME-180 cervical carcinoma line: modulation by specific inhibitors of DNA topoisomerase II.
Topics: Cell Communication; Cell Survival; DNA Topoisomerases, Type II; Drug Synergism; Etoposide; Female; Kinetics; Lymphotoxin-alpha; Mitomycin; Mitomycins; Teniposide; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Uterine Cervical Neoplasms | 1989 |
Isolation of two Chinese hamster ovary cell mutants hypersensitive to topoisomerase II inhibitors and cross-resistant to peroxides.
Topics: Amsacrine; Animals; Cell Line; Cell Survival; Cricetinae; Dactinomycin; DNA Topoisomerases, Type II; Doxorubicin; Drug Resistance; Etoposide; Female; Mitoxantrone; Mutation; Ovary; Teniposide; Topoisomerase II Inhibitors | 1989 |
Altered formation of DNA in human cells treated with inhibitors of DNA topoisomerase II (etoposide and teniposide).
Topics: DNA Replication; DNA, Neoplasm; Etoposide; Humans; Kinetics; Melanoma; Podophyllotoxin; Teniposide; Thymidine; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 1989 |
Expression of protein-associated DNA damage in the alkaline elution assay in the absence of enzymatic deproteinization.
Topics: Animals; Cell Line; DNA Damage; DNA Replication; DNA Topoisomerases, Type II; DNA, Neoplasm; Endopeptidase K; Etoposide; Humans; Hydrogen-Ion Concentration; Leukemia L1210; Liver Neoplasms, Experimental; Mice; Mitoxantrone; Podophyllotoxin; Protein Binding; Rats; Serine Endopeptidases; Teniposide; Tumor Cells, Cultured | 1989 |
Anaphylactic reactions to teniposide.
Topics: Adolescent; Anaphylaxis; Child; Child, Preschool; Etoposide; Humans; Infusions, Intravenous; Podophyllotoxin; Teniposide | 1989 |
[VM-26 and VP-16 salvage therapy for refractory germinal testicular cancers].
Topics: Adult; Choriocarcinoma; Dysgerminoma; Etoposide; Humans; Male; Middle Aged; Podophyllotoxin; Teniposide; Teratoma; Testicular Neoplasms | 1989 |
Automated reversed-phase chromatographic analysis of etoposide and teniposide in plasma by using on-line surfactant-mediated sample clean-up and column-switching.
Topics: Chromatography, High Pressure Liquid; Electrochemistry; Etoposide; Humans; Podophyllotoxin; Spectrometry, Fluorescence; Teniposide | 1989 |
Treatment strategies in relation to drug action.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; DNA Topoisomerases, Type II; Etoposide; Hodgkin Disease; Humans; Leukemia; Lung Neoplasms; Lymphoma, Non-Hodgkin; Neoplasms; Podophyllotoxin; Teniposide | 1987 |
Swiveling and decatenation of replicating simian virus 40 genomes in vivo.
Topics: Animals; Camptothecin; Cell Line; DNA Replication; DNA, Viral; Etoposide; Genes, Viral; Intercalating Agents; Simian virus 40; Teniposide; Topoisomerase II Inhibitors; Virus Replication | 1988 |
Topoisomerase-II-mediated lesions in nascent DNA: comparison of the effects of epipodophyllotoxin derivatives, VM-26 and VP-16, and 9-anilinoacridine derivatives, m-AMSA and o-AMSA.
Topics: Adenosine Triphosphate; Amsacrine; Animals; Cross-Linking Reagents; DNA; DNA Damage; DNA Replication; DNA Topoisomerases, Type II; DNA, Neoplasm; Etoposide; Leukemia L1210; Mice; Novobiocin; Podophyllotoxin; Teniposide; Topoisomerase II Inhibitors | 1988 |
DNA binding by epipodophyllotoxins and N-acyl anthracyclines: implications for mechanism of topoisomerase II inhibition.
Topics: Antibiotics, Antineoplastic; DNA; DNA, Mitochondrial; Etoposide; In Vitro Techniques; Plasmids; Podophyllotoxin; Teniposide; Topoisomerase II Inhibitors | 1988 |
Podophyllotoxins for brain metastases of small cell lung cancer.
Topics: Brain Neoplasms; Carcinoma, Small Cell; Etoposide; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin; Teniposide | 1988 |
Anticancer drugs as inhibitors of two polymorphic cytochrome P450 enzymes, debrisoquin and mephenytoin hydroxylase, in human liver microsomes.
Topics: Antineoplastic Agents; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme Inhibitors; Etoposide; Flavonoids; Humans; Kinetics; Microsomes, Liver; Mixed Function Oxygenases; Polymorphism, Genetic; Teniposide | 1989 |
Identification of DNA topoisomerase II as an intracellular target of antitumor epipodophyllotoxins in simian virus 40-infected monkey cells.
Topics: Animals; Cells, Cultured; Chemical Precipitation; DNA Topoisomerases, Type II; DNA, Viral; Etoposide; Haplorhini; Novobiocin; Podophyllotoxin; Simian virus 40; Teniposide | 1985 |
Peroxidative free radical formation and O-demethylation of etoposide(VP-16) and teniposide(VM-26).
Topics: Chromatography, High Pressure Liquid; Electron Spin Resonance Spectroscopy; Etoposide; Free Radicals; Horseradish Peroxidase; Mass Spectrometry; Oxidoreductases, O-Demethylating; Peroxides; Podophyllotoxin; Prostaglandin-Endoperoxide Synthases; Quinones; Teniposide | 1986 |
DNA breakage in human lung carcinoma cells and nuclei that are naturally sensitive or resistant to etoposide and teniposide.
Topics: Adenocarcinoma; Adenosine Triphosphate; Carcinoma, Small Cell; Cell Division; Cell Nucleus; Cells, Cultured; DNA; DNA, Single-Stranded; Drug Resistance; Etoposide; Humans; Intercalating Agents; Lung Neoplasms; Podophyllotoxin; Teniposide; Topoisomerase II Inhibitors | 1986 |
Membrane ordering effects of the anticancer agent VM-26.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Carcinoma, Ehrlich Tumor; Cell Line; Cell Membrane; Cholesterol; Cyclic N-Oxides; Dimyristoylphosphatidylcholine; Electron Spin Resonance Spectroscopy; Etoposide; Humans; Leukemia; Lipid Bilayers; Liposomes; Male; Membrane Lipids; Mice; Podophyllotoxin; Spin Labels; Teniposide | 1986 |
5,6-Dichloro-1-beta-O-ribofuranosylbenzimidazole induces DNA damage by interfering with DNA topoisomerase II.
Topics: Aphidicolin; Cells, Cultured; Chemical Precipitation; Dichlororibofuranosylbenzimidazole; Diterpenes; DNA; Electrophoresis, Agar Gel; Etoposide; Humans; Novobiocin; Proteins; Ribonucleosides; Teniposide; Topoisomerase II Inhibitors | 1987 |
Tumor necrosis factor enhances the in vitro and in vivo efficacy of chemotherapeutic drugs targeted at DNA topoisomerase II in the treatment of murine bladder cancer.
Topics: Animals; Antineoplastic Agents; Dactinomycin; DNA Topoisomerases, Type II; Doxorubicin; Etoposide; Female; Glycoproteins; Macrophage Activation; Mice; Recombinant Proteins; Teniposide; Tumor Necrosis Factor-alpha; Urinary Bladder Neoplasms | 1987 |
Protein-linked DNA strand breaks produced by etoposide and teniposide in mouse L1210 and human VA-13 and HT-29 cell lines: relationship to cytotoxicity.
Topics: Animals; Cell Line; Cell Survival; DNA Topoisomerases, Type II; DNA, Neoplasm; Etoposide; Humans; Kinetics; Leukemia L1210; Podophyllotoxin; Teniposide | 1987 |
Structure-bioactivation relationship of a series of podophyllotoxin derivatives.
Topics: Animals; Cell Survival; Cytochrome P-450 Enzyme System; Etoposide; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Podophyllotoxin; Rats; Rats, Inbred Strains; Spectrophotometry; Structure-Activity Relationship; Teniposide | 1988 |
Repeated high-dose chemotherapy followed by purged autologous bone marrow transplantation as consolidation therapy in metastatic neuroblastoma.
Topics: Abdominal Neoplasms; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Bone Marrow Transplantation; Carmustine; Child; Child, Preschool; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Gastrointestinal Diseases; Humans; Infant; Infections; Melphalan; Neuroblastoma; Teniposide; Thoracic Neoplasms; Transplantation, Autologous; Vincristine | 1987 |
Etoposide (VP16) and teniposide (VM26): novel anticancer drugs, strongly mutagenic in mammalian but not prokaryotic test systems.
Topics: Animals; Cell Line; Escherichia coli; Etoposide; Hypoxanthine Phosphoribosyltransferase; L Cells; Mice; Mutagenicity Tests; Mutagens; Mutation; Podophyllotoxin; Salmonella typhimurium; Teniposide | 1987 |
Synthesis and structure-activity relationships among glycosidic derivatives of 4'-demethylepipodophyllotoxin and epipodophyllotoxin, showing VM26- and VP16-213-like activities.
Topics: Antineoplastic Agents; Cell Line; Drug Resistance; Etoposide; Podophyllotoxin; Structure-Activity Relationship; Teniposide | 1987 |
Synthesis and biological activities of the C-4 esters of 4'-demethylepipodophyllotoxin.
Topics: Antineoplastic Agents; Cell Line; Drug Resistance; Esters; Etoposide; Mitotic Index; Podophyllotoxin; Structure-Activity Relationship; Teniposide | 1987 |
Non-Hodgkin's lymphomas in the elderly: prospective studies with specifically devised chemotherapy regimens in 66 patients.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Drug Evaluation; Etoposide; Female; Humans; Lymphoma, Non-Hodgkin; Male; Podophyllotoxin; Prednimustine; Prospective Studies; Teniposide | 1987 |
Comparison between VP 16 and VM 26 in Lewis lung carcinoma of the mouse.
Topics: Animals; Body Weight; Cell Count; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Etoposide; Kinetics; Leukocyte Count; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Podophyllotoxin; Teniposide | 1986 |
Quantification of teniposide in human serum by high-performance liquid chromatography with electrochemical detection.
Topics: Carcinoma; Chromatography, High Pressure Liquid; Electrochemistry; Etoposide; Female; Humans; Indicators and Reagents; Ovarian Neoplasms; Podophyllotoxin; Teniposide; Time Factors | 1986 |
Vitamin A: failure to demonstrate in mice an anti-tumour effect, whether combined with cytotoxic drugs or not.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cisplatin; Cyclophosphamide; Etoposide; Female; Leukemia L1210; Leukemia, Experimental; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Transplantation; Neoplasms, Experimental; Teniposide; Vitamin A | 1986 |
[Mutagenicity tests of etoposide and teniposide].
Topics: Animals; Etoposide; Male; Mice; Mutagenicity Tests; Podophyllotoxin; Teniposide | 1986 |
The effect of the two epipodophyllotoxin derivatives etoposide (VP-16) and teniposide (VM-26) on cell lines established from patients with small cell carcinoma of the lung.
Topics: Animals; Carcinoma, Squamous Cell; Cell Cycle; Cell Line; Cell Survival; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Resistance; Etoposide; Lung Neoplasms; Podophyllotoxin; Teniposide | 1987 |
Single- and double-strand DNA breakage and repair in human lung adenocarcinoma cells exposed to etoposide and teniposide.
Topics: Adenocarcinoma; Aminoacridines; Amsacrine; Cells, Cultured; DNA; DNA Repair; Etoposide; Humans; Lung Neoplasms; Podophyllotoxin; Teniposide | 1985 |
Inhibition of 1-beta-D-arabinofuranosylcytosine transport and net accumulation by teniposide and etoposide in Ehrlich ascites cells and human leukemic blasts.
Topics: Animals; Binding Sites; Biological Transport; Carcinoma, Ehrlich Tumor; Cells, Cultured; Cytarabine; Etoposide; Humans; Leukemia; Male; Mice; Mice, Inbred Strains; Podophyllotoxin; Teniposide; Thioinosine; Tritium | 1985 |
Radioimmunoassay for etoposide and teniposide.
Topics: Animals; Antibody Affinity; Cross Reactions; Dogs; Etoposide; Humans; Liver; Metabolic Clearance Rate; Mice; Podophyllotoxin; Rabbits; Radioimmunoassay; Teniposide | 1985 |
Nonintercalative antitumor drugs interfere with the breakage-reunion reaction of mammalian DNA topoisomerase II.
Topics: Animals; Cattle; DNA, Neoplasm; Etoposide; HeLa Cells; Humans; Kinetics; Phosphorus Radioisotopes; Podophyllotoxin; Teniposide; Thymus Gland; Topoisomerase II Inhibitors | 1984 |
Role of topoisomerase II in mediating epipodophyllotoxin-induced DNA cleavage.
Topics: Animals; Cattle; Cell Nucleus; Cell Survival; DNA Topoisomerases, Type II; DNA, Neoplasm; Etoposide; Leukemia L1210; Mice; Podophyllotoxin; Structure-Activity Relationship; Teniposide; Thymus Gland | 1984 |
Clinical trials in cancer medicine.
Topics: Adult; Antineoplastic Agents; Bleomycin; Breast Neoplasms; Clinical Trials as Topic; Doxorubicin; Etoposide; Female; Humans; Male; Methotrexate; Platinum; Tamoxifen; Teniposide; Testicular Neoplasms | 1980 |
Teniposide (VM-26)- and etoposide (VP-16-213)-induced augmentation of methotrexate transport and polyglutamylation in Ehrlich ascites tumor cells in vitro.
Topics: Animals; Biological Transport; Carcinoma, Ehrlich Tumor; Cells, Cultured; Chlorides; Etoposide; Glucose; Kinetics; Methotrexate; Mice; Peptides; Podophyllotoxin; Polyglutamic Acid; Teniposide; Vincristine; Water | 1982 |
Inhibition of the DNA catenation activity of type II topoisomerase by VP16-213 and VM26.
Topics: Animals; DNA Topoisomerases, Type I; DNA, Neoplasm; Etoposide; Liver Neoplasms, Experimental; Podophyllotoxin; Rats; Structure-Activity Relationship; Teniposide; Topoisomerase II Inhibitors | 1984 |
[Action of alkaloids from podophyllin on the response of pancreatic beta-cells of the rabbit to tolbutamide].
Topics: Animals; Etoposide; Insulin; Insulin Secretion; Islets of Langerhans; Podophyllotoxin; Rabbits; Teniposide; Tolbutamide | 1983 |
Ammonium acetate: a general purpose buffer for clinical applications of high-performance liquid chromatography.
Topics: Acetates; Bilirubin; Biogenic Amines; Buffers; Catecholamines; Chromatography, High Pressure Liquid; Creatinine; Etoposide; Porphyrins; Retinoids; Teniposide; Verapamil | 1984 |
Establishment of an etoposide-resistant human epithelial tumour cell line in vitro: characterization of patterns of cross-resistance and drug sensitivities.
Topics: Carcinoma, Squamous Cell; Cell Line; Cisplatin; DNA, Neoplasm; Drug Resistance; Etoposide; Fluorouracil; Humans; Podophyllotoxin; Teniposide; Tongue Neoplasms; Vincristine; X-Rays | 1984 |
Comparative cytotoxic and cytokinetic effects of the epipodophyllotoxins 4'-demethylepipodophyllotoxin-9-(4,6-O-2-ethylidene-beta-D-glucopyranoside) and 4'-demethylepipodophyllotoxin-9-(4,6-O-2-thenylidene-beta-D-glucopyranoside) and their metabolites on
Topics: Cell Cycle; Cell Line; Cell Survival; Clone Cells; Dose-Response Relationship, Drug; Etoposide; Humans; Kinetics; Leukemia, Lymphoid; Podophyllotoxin; Structure-Activity Relationship; Teniposide | 1983 |
4'-Demethylepipodophyllotoxin-beta-D-glucoside: a new podophyllotoxin derivative with VM-26-like and VP-16-213-like activities.
Topics: Animals; Cell Line; Cricetinae; Cricetulus; Drug Resistance; Etoposide; Female; Ovary; Podophyllotoxin; Structure-Activity Relationship; Teniposide | 1984 |
Automated liquid chromatographic analysis of the anti-tumorigenic drugs etoposide (VP 16-213) and teniposide (VM 26).
Topics: Autoanalysis; Chromatography, Liquid; Etoposide; Humans; Hydrolysis; Podophyllotoxin; Teniposide | 1983 |
Skin ulceration potential without therapeutic anticancer activity for epipodophyllotoxin commercial diluents.
Topics: Adenocarcinoma; Animals; Cell Survival; Colonic Neoplasms; Etoposide; Humans; Leukemia P388; Leukemia, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Podophyllotoxin; Skin Ulcer; Solvents; Teniposide; Tumor Stem Cell Assay | 1983 |
High-performance liquid chromatographic analysis of the semisynthetic epipodophyllotoxins teniposide and etoposide using electrochemical detection.
Topics: Body Fluids; Chromatography, High Pressure Liquid; Electrochemistry; Etoposide; Humans; Kinetics; Podophyllotoxin; Teniposide | 1984 |
Comparison of cytotoxicity and DNA breakage activity of congeners of podophyllotoxin including VP16-213 and VM26: a quantitative structure-activity relationship.
Topics: Adenocarcinoma; Cell Line; Cell Survival; DNA; DNA Repair; Etoposide; Humans; Kinetics; Lung Neoplasms; Podophyllotoxin; Structure-Activity Relationship; Teniposide | 1984 |
Etoposide (VP-16-213) in malignant brain tumors: a phase II study.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Drug Evaluation; Etoposide; Female; Glioma; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Podophyllotoxin; Teniposide; Time Factors; Tomography, X-Ray Computed | 1984 |
New anticancer drug class.
Topics: Child; Etoposide; Humans; Legislation, Drug; Neoplasms; Podophyllotoxin; Teniposide; United States | 1983 |
Genetic, biochemical, and cross-resistance studies with mutants of Chinese hamster ovary cells resistant to the anticancer drugs, VM-26 and VP16-213.
Topics: Animals; Antineoplastic Agents; Biological Transport; Cell Line; Cricetinae; Cricetulus; Daunorubicin; Drug Resistance; Etoposide; Female; Mutation; Ovary; Phenotype; Podophyllotoxin; Teniposide | 1983 |
Glycosylated podophyllotoxin congeners: loss of microtubule inhibition and permission of invasion in vitro.
Topics: Animals; Cell Division; Chick Embryo; Etoposide; Fibrosarcoma; Mice; Microtubules; Myocardium; Organ Culture Techniques; Podophyllotoxin; Teniposide | 1982 |
Etoposide (VP16-213) and teniposide (VM26) comparative in vitro activities in human tumors.
Topics: Antineoplastic Agents; Cells, Cultured; Etoposide; Humans; Neoplasms; Neoplasms, Experimental; Podophyllotoxin; Teniposide | 1982 |
Pharmacokinetics of Teniposide (VM26) and etoposide (VP16-213) in children with cancer.
Topics: Biotransformation; Child; Chromatography, High Pressure Liquid; Etoposide; Humans; Kinetics; Leukemia; Models, Biological; Neoplasms; Podophyllotoxin; Teniposide | 1982 |
Combination chemotherapy of the epipodophyllotoxin derivatives, teniposide and etoposide. A pharmacodynamic rationale?
Topics: Adult; Aged; Ascitic Fluid; Drug Interactions; Drug Therapy, Combination; Etoposide; Female; Humans; Kinetics; Male; Middle Aged; Models, Biological; Podophyllotoxin; Protein Binding; Teniposide | 1982 |
Analysis of the anticancer drugs etoposide (VP 16-213) and teniposide (VM 26) by high-performance liquid chromatography with fluorescence detection.
Topics: Chromatography, High Pressure Liquid; Etoposide; Humans; Podophyllotoxin; Reference Values; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Teniposide; Time Factors | 1981 |
Analysis of the anticancer drugs VP 16-213 and VM 26 and their metabolites by high-performance liquid chromatography.
Topics: Adult; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Etoposide; Humans; Isomerism; Kinetics; Male; Podophyllotoxin; Spectrometry, Fluorescence; Teniposide | 1980 |
Overexpression of the RI alpha subunit of protein kinase A confers hypersensitivity to topoisomerase II inhibitors and 8-chloro-cyclic adenosine 3'5'-monophosphate in Chinese hamster ovary cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Antineoplastic Agents; Bleomycin; Cell Division; CHO Cells; Cisplatin; Cricetinae; Cyclic AMP-Dependent Protein Kinases; Drug Screening Assays, Antitumor; Etoposide; Teniposide | 1994 |
Analysis of eukaryotic topoisomerase II cleavage sites in the presence of the quinolone CP-115,953 reveals drug-dependent and -independent recognition elements.
Topics: Amsacrine; Anti-Infective Agents; Base Sequence; DNA; DNA Topoisomerases, Type II; Etoposide; Fluoroquinolones; Humans; Hydrolysis; Molecular Sequence Data; Quinolones; Teniposide; Topoisomerase II Inhibitors | 1995 |
ALL-1 gene rearrangements in DNA topoisomerase II inhibitor-related leukemia in children.
Topics: Acute Disease; Adolescent; Bone Marrow Transplantation; Child; Child, Preschool; Chromosome Aberrations; Chromosome Deletion; Chromosomes, Human, Pair 11; Combined Modality Therapy; Dactinomycin; DNA-Binding Proteins; Etoposide; Female; Genes; Histone-Lysine N-Methyltransferase; Humans; Infant; Leukemia; Leukemia, Myeloid; Leukemia, Radiation-Induced; Male; Myelodysplastic Syndromes; Myeloid-Lymphoid Leukemia Protein; Neoplasm Proteins; Neoplasms; Neoplasms, Second Primary; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proto-Oncogenes; Radiotherapy; Teniposide; Topoisomerase II Inhibitors; Transcription Factors; Translocation, Genetic; Whole-Body Irradiation | 1995 |
Different topoisomerase II antitumor drugs direct similar specific long-range fragmentation of an amplified c-MYC gene locus in living cells and in high-salt-extracted nuclei.
Topics: Amsacrine; Antineoplastic Agents; Carcinoma, Small Cell; Cell Fractionation; Cell Line; Cell Nucleus; DNA Damage; DNA Topoisomerases, Type II; DNA, Neoplasm; Etoposide; Exons; Genes, myc; Humans; Lung Neoplasms; Restriction Mapping; Saline Solution, Hypertonic; Teniposide; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 1995 |
Multidrug resistance-associated protein gene overexpression and reduced drug sensitivity of topoisomerase II in a human breast carcinoma MCF7 cell line selected for etoposide resistance.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Carrier Proteins; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Drug Resistance; Etoposide; Female; Humans; Membrane Glycoproteins; RNA, Messenger; Teniposide; Tumor Cells, Cultured | 1994 |
Teniposide for meningeal carcinomatosis of small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carboplatin; Carcinoma, Small Cell; Cyclophosphamide; Dexamethasone; Doxorubicin; Etoposide; Female; Humans; Ifosfamide; Immunologic Factors; Injections, Spinal; Interferon-gamma; Lung Neoplasms; Meningeal Neoplasms; Middle Aged; Morphine; Teniposide; Vincristine | 1993 |
Multiple drug resistance in the human ovarian carcinoma cell line OAW42-A.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; Doxorubicin; Drug Resistance; Etoposide; Female; Humans; Membrane Glycoproteins; Oligonucleotides, Antisense; Ovarian Neoplasms; Teniposide; Transfection; Tumor Cells, Cultured; Vincristine | 1993 |
O-demethylation of epipodophyllotoxins is catalyzed by human cytochrome P450 3A4.
Topics: Biotransformation; Catalysis; Catechols; Chromatography, High Pressure Liquid; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Erythromycin; Etoposide; Humans; Methylation; Microsomes, Liver; Midazolam; Mixed Function Oxygenases; Teniposide | 1994 |
Different modes of cell-killing action between DNA topoisomerase I and II inhibitors revealed by kinetic analysis.
Topics: Amsacrine; Antineoplastic Agents; Camptothecin; Carbazoles; Cell Cycle; Colonic Neoplasms; Diterpenes; DNA Replication; Dose-Response Relationship, Drug; Etoposide; Flow Cytometry; G2 Phase; Humans; Indoles; Mitosis; Quinones; S Phase; Teniposide; Time Factors; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1994 |
Human autopsy tissue distribution of the epipodophyllotoxins etoposide and teniposide.
Topics: Chromatography, High Pressure Liquid; Etoposide; Female; Half-Life; Humans; Male; Teniposide; Tissue Distribution | 1993 |
Enhanced expression of the DNA topoisomerase II gene in response to heat shock stress in human epidermoid cancer KB cells.
Topics: Camptothecin; DNA Topoisomerases, Type II; Etoposide; Gene Expression; Hot Temperature; Humans; Irinotecan; KB Cells; Neoplasms; RNA, Messenger; Teniposide | 1993 |
[In vitro comparison of podophyllotoxin analogues; etoposide, teniposide and NK 611 using human lung cancer cell lines].
Topics: Adenocarcinoma; Antineoplastic Agents; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cell Division; Drug Resistance; Drug Screening Assays, Antitumor; Etoposide; Humans; Lung Neoplasms; Podophyllotoxin; Teniposide; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1993 |
The mechanism of epipodophyllotoxin-induced thymocyte apoptosis: possible role of a novel Ca(2+)-independent protein kinase.
Topics: Animals; Apoptosis; Calcium; Cells, Cultured; Dexamethasone; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Etoposide; Female; Mice; Mice, Inbred C3H; Protein Kinase C; Signal Transduction; T-Lymphocytes; Teniposide; Thymus Gland; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors | 1993 |
Biomodulation by hyperthermia of topoisomerase II-targeting drugs in human colorectal cancer cells.
Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Cycle; Colorectal Neoplasms; Drug Resistance, Neoplasm; Enzyme Inhibitors; Etoposide; Hot Temperature; Humans; Neoplasm Proteins; Teniposide; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Tumor Stem Cell Assay; Vincristine | 1995 |
Effects of DNA topoisomerase inhibitors on nonhomologous and homologous recombination in mammalian cells.
Topics: Adenine Phosphoribosyltransferase; Animals; Antineoplastic Agents, Phytogenic; Camptothecin; CHO Cells; Chromosome Aberrations; Cricetinae; Diketopiperazines; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Enzyme Inhibitors; Etoposide; Mutagenesis; Mutagenicity Tests; Nucleic Acid Heteroduplexes; Piperazines; Recombination, Genetic; Teniposide; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Transfection | 1996 |
Distribution of 11q23 breakpoints within the MLL breakpoint cluster region in de novo acute leukemia and in treatment-related acute myeloid leukemia: correlation with scaffold attachment regions and topoisomerase II consensus binding sites.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Agents, Phytogenic; Base Sequence; Binding Sites; Centromere; Child; Child, Preschool; Chromatin; Chromosomes, Human, Pair 11; Consensus Sequence; DNA Topoisomerases, Type II; DNA-Binding Proteins; DNA, Neoplasm; Etoposide; Female; Histone-Lysine N-Methyltransferase; Humans; Infant; Leukemia; Male; Middle Aged; Molecular Sequence Data; Myeloid-Lymphoid Leukemia Protein; Neoplasms, Second Primary; Proto-Oncogenes; Telomere; Teniposide; Topoisomerase II Inhibitors; Transcription Factors; Translocation, Genetic; Tumor Cells, Cultured | 1996 |
Mechanisms of resistance of human small cell lung cancer lines selected in VP-16 and cisplatin.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cadmium; Cadmium Chloride; Carcinoma, Small Cell; Cell Line; Chlorides; Cisplatin; Cross Reactions; DNA; DNA Topoisomerases, Type II; Drug Resistance, Neoplasm; Etoposide; Gene Expression Regulation, Neoplastic; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Humans; Lung Neoplasms; Metallothionein; Platinum Compounds; Podophyllotoxin; Teniposide; Tumor Cells, Cultured; Vinca Alkaloids | 1996 |
Induction of somatic mutation and recombination by four inhibitors of eukaryotic topoisomerases assayed in the wing spot test of Drosophila melanogaster.
Topics: Animals; Camptothecin; Drosophila melanogaster; Ellipticines; Enzyme Inhibitors; Etoposide; Female; Male; Mutagenicity Tests; Mutation; Recombination, Genetic; Teniposide; Topoisomerase I Inhibitors | 1996 |
Overexpression of multidrug resistance protein gene in human cancer cell lines selected for drug resistance to epipodophyllotoxins.
Topics: Antineoplastic Agents, Phytogenic; ATP-Binding Cassette Transporters; Drug Resistance, Multiple; Etoposide; Gene Expression Regulation, Neoplastic; Humans; Multidrug Resistance-Associated Proteins; Neoplasms; Teniposide; Tumor Cells, Cultured | 1996 |
Ultrafiltration and subsequent high performance liquid chromatography for in vivo determinations of the protein binding of etoposide.
Topics: Antineoplastic Agents; Blood Proteins; Chromatography, High Pressure Liquid; Dialysis; Etoposide; Humans; Leukemia, Myeloid, Acute; Reference Values; Teniposide; Ultrafiltration | 1996 |
Inactivation of topoisomerase I or II may lead to recombination or to aberrant replication termination on both SV40 and yeast 2 micron DNA.
Topics: Camptothecin; DNA Replication; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA, Circular; DNA, Fungal; DNA, Viral; Electrophoresis, Gel, Two-Dimensional; Enzyme Activation; Enzyme Inhibitors; Etoposide; Hypertonic Solutions; Mutation; Plasmids; Recombination, Genetic; Simian virus 40; Teniposide; Thiobarbiturates; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Yeasts | 1996 |
Double knockout of the MRP gene leads to increased drug sensitivity in vitro.
Topics: Animals; Antineoplastic Agents; Arsenites; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Cell Line; Colchicine; Cytarabine; Daunorubicin; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Gene Targeting; Humans; Mice; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Sodium Compounds; Stem Cells; Teniposide; Vincristine | 1996 |
Bcl-2 and Bcl-XL can differentially block chemotherapy-induced cell death.
Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-X Protein; Clone Cells; Drug Resistance, Neoplasm; Etoposide; Fluorouracil; Gamma Rays; Genes, bcl-2; Humans; Hydroxyurea; Methotrexate; Mice; Proto-Oncogene Proteins c-bcl-2; Recombinant Fusion Proteins; S Phase; Teniposide; Transfection; Vincristine | 1997 |
Discovery of podophyllotoxins.
Topics: Animals; Antineoplastic Agents, Phytogenic; Enzyme Inhibitors; Etoposide; History, 19th Century; History, 20th Century; Humans; Podophyllotoxin; Teniposide; Topoisomerase II Inhibitors | 1998 |
Improved targeting of brain tumors using dexrazoxane rescue of topoisomerase II combined with supralethal doses of etoposide and teniposide.
Topics: Amsacrine; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Drug Administration Schedule; Etoposide; Female; Mice; Mice, Inbred Strains; Razoxane; Survival Rate; Teniposide; Topoisomerase II Inhibitors | 1998 |
Cyclic AMP-dependent protein kinase type I is involved in hypersensitivity of human breast cells to topoisomerase II inhibitors.
Topics: Amsacrine; Bleomycin; Breast Neoplasms; Cell Division; Cell Survival; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; DNA Topoisomerases, Type II; Etoposide; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; Recombinant Proteins; Teniposide; Topoisomerase II Inhibitors; Transfection; Transforming Growth Factor alpha; Tumor Cells, Cultured | 1995 |
DNA damage signals induction of fas ligand in tumor cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; CHO Cells; Cricetinae; DNA; DNA Damage; Doxorubicin; Enzyme Inhibitors; Etoposide; Fas Ligand Protein; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; Jurkat Cells; Membrane Glycoproteins; Nucleic Acid Synthesis Inhibitors; Promoter Regions, Genetic; Razoxane; Recombinant Fusion Proteins; Signal Transduction; Teniposide; Thiobarbiturates; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Up-Regulation | 1999 |
Changes in nuclear protein kinase C-delta holoenzyme, its catalytic fragments, and its activity in polyomavirus-transformed pyF111 rat fibroblasts while proliferating and following exposure to apoptogenic topoisomerase-II inhibitors.
Topics: Animals; Caspases; Catalysis; Cell Division; Cell Transformation, Viral; Doxorubicin; Enzyme Inhibitors; Etoposide; Fibroblasts; Isoenzymes; Nuclear Envelope; Polyomavirus; Protein Kinase C; Protein Kinase C-delta; Rats; Rats, Inbred F344; Teniposide; Topoisomerase II Inhibitors | 1999 |
MRP3, an organic anion transporter able to transport anti-cancer drugs.
Topics: Animals; Antineoplastic Agents; ATP-Binding Cassette Transporters; Cell Line; DNA, Complementary; Dogs; Drug Carriers; Drug Resistance, Multiple; Etoposide; Gene Expression; Humans; Methotrexate; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Teniposide | 1999 |
[VP-16 and VM-26 plus platinum drugs combined with radiotherapy in the treatment of small cell lung cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cisplatin; Cobalt Radioisotopes; Combined Modality Therapy; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Teniposide | 1998 |
Effect of extracellular magnesium on topoisomerase II activity and expression in human leukemia HL-60 cells.
Topics: Apoptosis; Cell Differentiation; Cell Division; Dimethyl Sulfoxide; DNA Topoisomerases, Type II; Enzyme Inhibitors; Etoposide; HL-60 Cells; Humans; Intracellular Fluid; Magnesium; Teniposide; Topoisomerase II Inhibitors | 2000 |
In vitro drug resistance profiles of adult versus childhood acute lymphoblastic leukaemia.
Topics: Adolescent; Adult; Age Factors; Antineoplastic Agents; Asparaginase; Bone Marrow Cells; Child; Child, Preschool; Cytarabine; Daunorubicin; Dexamethasone; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Idarubicin; Ifosfamide; Infant; Leukemia, Prolymphocytic; Leukemia, T-Cell; Male; Mercaptopurine; Middle Aged; Mitoxantrone; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prognosis; Statistics, Nonparametric; Teniposide; Thioguanine; Vincristine | 2000 |
Herbimycin A enhances apoptotic effect of chemotherapeutic drugs on K562 cells.
Topics: Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzoquinones; Etoposide; HL-60 Cells; Humans; K562 Cells; Lactams, Macrocyclic; Mitoxantrone; Protein-Tyrosine Kinases; Quinones; Rifabutin; Teniposide | 1998 |
Atp-bound topoisomerase ii as a target for antitumor drugs.
Topics: Adenosine Triphosphate; Amino Acid Substitution; Amsacrine; Animals; Antineoplastic Agents; Cattle; DNA Topoisomerases, Type II; Doxorubicin; Etoposide; Kinetics; Mitoxantrone; Mutagenesis, Site-Directed; Recombinant Proteins; Teniposide; Thymus Gland | 2001 |
Topoisomerase IIalpha and other drug resistance markers in advanced non-small cell lung cancer.
Topics: Amino Acid Substitution; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; ATP-Binding Cassette Transporters; Biomarkers; Carcinoma, Non-Small-Cell Lung; Cisplatin; Cyclophosphamide; DNA Mutational Analysis; DNA Topoisomerases, Type II; DNA-Binding Proteins; DNA, Neoplasm; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Ifosfamide; Isoenzymes; Ki-67 Antigen; Life Tables; Lung Neoplasms; Male; Middle Aged; Multidrug Resistance-Associated Proteins; Mutation, Missense; Neoplasm Proteins; Paclitaxel; Point Mutation; Prognosis; Reverse Transcriptase Polymerase Chain Reaction; Survival Analysis; Teniposide; Topotecan; Treatment Outcome; Vault Ribonucleoprotein Particles | 2001 |
Paclitaxel and lung cancer: new preparation. No therapeutic progress.
Topics: Antineoplastic Agents, Phytogenic; Cisplatin; Drug Therapy, Combination; Etoposide; Humans; Lung Neoplasms; Paclitaxel; Teniposide; Treatment Outcome | 2000 |
Prostaglandin A1 inhibits stress-induced NF-kappaB activation and reverses resistance to topoisomerase II inhibitors.
Topics: Animals; Blotting, Western; Brefeldin A; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Etoposide; Humans; Hypoxia; Luciferases; Mice; NF-kappa B; Prostaglandins A; Teniposide; Time Factors; Topoisomerase II Inhibitors; Transfection; Tumor Cells, Cultured | 2000 |
Toxoplasmic encephalitis in a non-HIV patient with follicular lymphoma.
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; CD4-Positive T-Lymphocytes; Cisplatin; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Etoposide; Fatal Outcome; Female; Humans; Immunocompromised Host; Interferon-alpha; Lymphoma, Follicular; Opportunistic Infections; Prednisone; Salvage Therapy; Teniposide; Toxoplasmosis, Cerebral; Vidarabine | 2002 |
Potent anti-cancer drug from witches' umbrella.
Topics: Agriculture; Antineoplastic Agents, Phytogenic; Etoposide; Plants, Medicinal; Podophyllum peltatum; Teniposide; United States | 2000 |
Role of early anthracycline dose-intensity according to expression of Philadelphia chromosome/BCR-ABL rearrangements in B-precursor adult acute lymphoblastic leukemia.
Topics: Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow Transplantation; Carmustine; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Dexamethasone; Disease-Free Survival; Doxorubicin; Etoposide; Female; Fusion Proteins, bcr-abl; Gene Expression Regulation, Leukemic; Humans; Idarubicin; Life Tables; Male; Melphalan; Mercaptopurine; Middle Aged; Neoplasm Proteins; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Retrospective Studies; Teniposide; Transplantation, Autologous; Treatment Outcome; Vincristine | 2000 |
Characterization of the drug resistance and transport properties of multidrug resistance protein 6 (MRP6, ABCC6).
Topics: Animals; Antineoplastic Agents; Biological Transport, Active; CHO Cells; Cricetinae; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Leukotriene C4; Multidrug Resistance-Associated Proteins; Teniposide; Transfection | 2002 |
Dental abnormalities in children after chemotherapy treatment for acute lymphoid leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Cytarabine; Dental Enamel Hypoplasia; Dexamethasone; Doxorubicin; Etoposide; Female; Humans; Infant; Male; Mercaptopurine; Methotrexate; Odontogenesis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Teniposide; Tooth Abnormalities; Tooth Diseases; Tooth Eruption; Tooth Root; Vincristine | 2003 |
Extraocular retinoblastoma: a 13-year experience.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Eye Enucleation; Female; Humans; Ifosfamide; Male; Retinal Neoplasms; Retinoblastoma; Teniposide; Time Factors; Vincristine | 2003 |
[Evaluation of efficacy of treatment for 30 children with neuroblastoma].
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Infant; Male; Neoplasm Staging; Neuroblastoma; Retrospective Studies; Teniposide; Treatment Outcome; Vincristine | 2003 |
Kinetics and regulation of cytochrome P450-mediated etoposide metabolism.
Topics: Adult; Blotting, Western; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; DNA Topoisomerases, Type II; Etoposide; Female; Hepatocytes; Humans; Kinetics; Male; Middle Aged; Polymerase Chain Reaction; Rifampin; RNA, Messenger; Spectrometry, Mass, Electrospray Ionization; Subcellular Fractions; Teniposide; Topoisomerase II Inhibitors | 2004 |
A mutation in Escherichia coli DNA gyrase conferring quinolone resistance results in sensitivity to drugs targeting eukaryotic topoisomerase II.
Topics: Anti-Bacterial Agents; Chromosome Mapping; DNA Gyrase; DNA, Superhelical; Drug Resistance, Bacterial; Enzyme Inhibitors; Escherichia coli; Etoposide; Microbial Sensitivity Tests; Mutagenesis, Site-Directed; Plasmids; Point Mutation; Quinolones; Reverse Transcriptase Polymerase Chain Reaction; Teniposide; Time Factors; Topoisomerase II Inhibitors | 2004 |
Risk of adverse events after completion of therapy for childhood acute lymphoblastic leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Combined Modality Therapy; Cranial Irradiation; Etoposide; Female; Humans; Infant; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Remission Induction; Risk Factors; Survival Rate; Teniposide | 2005 |
Retinoblastoma in children older than 5 years of age.
Topics: Age Distribution; Antineoplastic Combined Chemotherapy Protocols; Brazil; Chemotherapy, Adjuvant; Child; Child, Preschool; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Eye Enucleation; Eye Neoplasms; Female; Humans; Ifosfamide; Kaplan-Meier Estimate; Laser Coagulation; Male; Neoplasm Invasiveness; Neoplasm Staging; Radiotherapy, Adjuvant; Retinoblastoma; Teniposide; Treatment Outcome; Vincristine | 2007 |
The addition of ifosfamide/etoposide to cisplatin/teniposide improves the survival of children with retinoblastoma and orbital involvement.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Cisplatin; Etoposide; Female; Humans; Ifosfamide; Infant; Male; Retinal Neoplasms; Retinoblastoma; Sex Distribution; Survival Rate; Teniposide | 2007 |
Cytogenetic and molecular analysis of MLL rearrangements in acute lymphoblastic leukaemia survivors.
Topics: Adolescent; Adult; Base Sequence; Case-Control Studies; Child; Child, Preschool; Chromosomes, Human, Pair 11; Cytogenetic Analysis; Etoposide; Gene Rearrangement; Humans; Molecular Sequence Data; Myeloid-Lymphoid Leukemia Protein; Polymerase Chain Reaction; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Survivors; Teniposide; Translocation, Genetic | 2009 |
Determination of teniposide in rat plasma by ultra performance liquid chromatography electrospray ionization tandem mass spectrometry after intravenous administration.
Topics: Animals; Antineoplastic Agents; Chemical Fractionation; Chromatography, High Pressure Liquid; Drug Stability; Etoposide; Female; Injections, Intravenous; Linear Models; Rats; Rats, Wistar; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Teniposide | 2009 |
Novel regulation of nuclear factor-YB by miR-485-3p affects the expression of DNA topoisomerase IIα and drug responsiveness.
Topics: Antigens, Neoplasm; Antineoplastic Agents; CCAAT-Binding Factor; Cell Line, Tumor; DNA Topoisomerases, Type II; DNA-Binding Proteins; Down-Regulation; Drug Resistance, Neoplasm; Etoposide; Gene Expression Regulation, Enzymologic; Humans; MicroRNAs; Poly-ADP-Ribose Binding Proteins; Teniposide; Up-Regulation | 2011 |
Hypersensitivity reactions to anticancer agents: data mining of the public version of the FDA adverse event reporting system, AERS.
Topics: Adverse Drug Reaction Reporting Systems; Antineoplastic Agents; Asparaginase; Bayes Theorem; Data Mining; Docetaxel; Drug Hypersensitivity; Etoposide; Humans; Paclitaxel; Pharmacovigilance; Procarbazine; Prognosis; Taxoids; Teniposide; United States; United States Food and Drug Administration | 2011 |
DNA topoisomerase II inhibitors induce macrophage ABCA1 expression and cholesterol efflux-an LXR-dependent mechanism.
Topics: Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Cells, Cultured; Cholesterol; Electrophoretic Mobility Shift Assay; Etoposide; Fluorescent Antibody Technique; Foam Cells; Gene Expression Regulation; Liver X Receptors; Macrophages; Mice; Mice, Inbred C57BL; Orphan Nuclear Receptors; Promoter Regions, Genetic; Retinoid X Receptors; RNA, Small Interfering; Teniposide; Topoisomerase II Inhibitors | 2013 |
Regulation of Hepatic Cholesteryl Ester Transfer Protein Expression and Reverse Cholesterol Transport by Inhibition of DNA Topoisomerase II.
Topics: Animals; Cholesterol; Cholesterol Ester Transfer Proteins; DNA Topoisomerases, Type II; Etoposide; Gene Expression Regulation; Hep G2 Cells; Humans; Liver; Liver X Receptors; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Orphan Nuclear Receptors; Protein Transport; Teniposide; Topoisomerase II Inhibitors; Transcriptional Activation | 2015 |
A Highly Efficient Approach To Construct (epi)-Podophyllotoxin-4-O-glycosidic Linkages as well as Its Application in Concise Syntheses of Etoposide and Teniposide.
Topics: Antineoplastic Agents; Catalysis; Etoposide; Glycosides; Glycosylation; Molecular Structure; Podophyllotoxin; Teniposide | 2016 |
Separating chemotherapy-related developmental neurotoxicity from cytotoxicity in monolayer and neurosphere cultures of human fetal brain cells.
Topics: Antineoplastic Agents; Astrocytes; Brain; Cell Count; Cell Culture Techniques; Cell Survival; Cells, Cultured; Etoposide; Fetus; Glial Fibrillary Acidic Protein; Humans; Methylmercury Compounds; Neurons; Neurotoxicity Syndromes; Oxazines; Oxidation-Reduction; Spheroids, Cellular; Teniposide; Tubulin; Xanthenes | 2016 |
A novel cell-based screening assay for small-molecule MYB inhibitors identifies podophyllotoxins teniposide and etoposide as inhibitors of MYB activity.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; DNA Damage; Dose-Response Relationship, Drug; Etoposide; Gene Expression Regulation, Leukemic; High-Throughput Screening Assays; Humans; Leukocytes; Podophyllotoxin; Proto-Oncogene Proteins c-myb; Signal Transduction; Small Molecule Libraries; Teniposide | 2018 |