arginine and eflornithine

arginine has been researched along with eflornithine in 65 studies

Research

Studies (65)

Timeframe	Studies, this research(%)	All Research%
pre-1990	22 (33.85)	18.7374
1990's	22 (33.85)	18.2507
2000's	12 (18.46)	29.6817
2010's	9 (13.85)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Coffino, P; Tsirka, S	1
Bitonti, AJ; Kierszenbaum, F; Majumder, S; McCann, PP; Wirth, JJ	1
Basso, B; Kierszenbaum, F; Yakubu, MA	1
Fairlamb, AH; Hunter, KJ; Strobos, CA	2
Boyle, SM; Gruhn, CM	1
Byus, CV; Wu, VS	1
Kovacs, JA; Lipschik, GY; Masur, H	1
Khan, AJ; Minocha, SC	1
Blachier, F; Leclercq-Meyer, V; Malaisse, WJ; Marchand, J; Mathias, PC; Sener, A; Woussen-Colle, MC	1
Malaisse, WJ; Malaisse-Lagae, F; Owen, A; Sener, A	1
Daune, G; Gerhart, F; Grauffel, C; Seiler, N	1
Bacchi, CJ; Bitonti, AJ; McCann, PP; Sjoerdsma, A	1
Hiatt, AC; Malmberg, RL; McIndoo, J	1
Phillips, MA; Wang, CC	1
Eloranta, TO; Hyvönen, T; Pajula, RL; Smith, TK	1
Bitonti, AJ; Feirer, RP; McCann, PP; Slocum, RD	1
Boyle, SM; Cordes, D; Sriranganathan, N	1
Tabor, CW; Tabor, H	1
Galston, AW; Rajam, MV; Weinstein, LH	1
Bey, P; McCann, PP; Pösö, H; Sjoerdsma, A; Tanskanen, R	1
Bitonti, AJ; McCann, PP; Sjoerdsma, A	1
el-Fakahany, EE; Hu, J; Mahmoud, MI	1
Morgan, DM	1
Chmurzyńska, W; Grzelakowska-Sztabert, B; Manteuffel-Cymborowska, M; Peska, M	2
Bogle, RG; Mann, GE; Morgan, DM; Pearson, JD	1
Bedoya, AM; Hernandez, SM; Isola, EL; Lammel, EM; Schwarcz de Tarlovsky, MN	1
Brzozowski, T; Dembiński, A; Drozdowicz, D; Konturek, SJ; Stachura, J	1
Balaña-Fouce, R; Calonge, M; Cubría, JC; Ordóñez, D	1
Hittelman, WN; Hong, WK; Lee, JJ; Lotan, R; Mitchell, MF; Nishioka, K; Tortolero-Luna, G; Wharton, JT	1
Grossie, VB; Nishioka, K	1
Blachier, F; Mayeur, C; Robert, V; Selamnia, M	1
Cannavò, L; Ginoprelli, T; Ientile, R; Macaione, S; Pedale, S	1
Batchelor, GC; Fuller, LR; Joshi, M	1
Hernández, S; Schwarcz de Tarlovsky, S	1
Honkanen, RE; Sjöholm, A	1
Dai, YR; Galston, AW; Kaur-Sawhney, R	1
Galston, AW; Tiburcio, AF	1
Galston, AW; Osmeloski, JF; Weinstein, LH; Wettlaufer, SH	1
Galston, AW; Slocum, RD	1
Galston, AW; Kaur-Sawhney, R; Tiburcio, AF	1
Galston, AW; Kaur Sawhney, R; Shekhawat, NS	1
Galston, AW	1
Galston, AW; Rajam, MV	1
Cheever, AW; Fuentes, JM; Hesse, M; La Flamme, AC; Modolell, M; Pearce, EJ; Schito, M; Wynn, TA	1
Chornomaz, EM; Gárriz, A; Pieckenstain, FL; Ruiz, OA; Sánchez, DH	1
Caldefie, F; Chassagne, J; Cynober, L; Moinard, C; Tridon, A; Vasson, MP; Walrand, S	1
Couée, I; El Amrani, A; Hennion, F; Hummel, I; Martin-Tanguy, J	1
Chang, CI; Hein, TW; Kuo, L; Thengchaisri, N; Wang, W; Zhang, C	1
Akhtar, M; Blumberg, DR; Boucher, JL; Casero, RA; Chaturvedi, R; Cheng, Y; Cross, RK; Drachenberg, CB; Gobert, AP; Hacker, A; Mersey, BD; Wilson, KT	1
Allen, DA; Ashman, N; Harwood, SM; Kieswich, J; Mendes-Ribeiro, AC; Roberts, NB; Yaqoob, MM	1
Aizawa, S; Maeda, T; Shima, Y; Tamai, I; Tsuboi, I; Wakasawa, T	1
Bhagyalakshmi, N; Venkatachalam, L	1
Andrews, KL; Chin-Dusting, JF; Harris, EE; Huynh, NN	1
Haller, H; Kuczyk, MA; Lorenzen, JM; Scheller, F; Ückert, S	1
Chopde, CT; Kotagale, NR; Patel, MR; Shelkar, GP; Taksande, BG; Ugale, RR	1
Chopde, CT; Gahane, AY; Kotagale, NR; Taksande, BG; Ugale, RR	1
Aloj, SM; Chiaviello, A; Paciello, I; Palumbo, G; Veneziani, BM	1
Huang, Z; Mao, X; Qiao, S; Wang, F; Wu, G; Zeng, X	1
Aglawe, MM; Chopde, CT; Kotagale, NR; Taksande, BG; Tripathi, SJ; Umekar, MJ	1
Abu-Lubad, M; Al-Zeer, MA; Meyer, TF	1
Brown, CM; Colton, CA; Everhart, AL; Gunn, MD; Hoofnagle, AN; Jansen, M; Kan, MJ; Lee, JE; Vitek, MP; Wilson, JG	1
Karnaushenko, OV; Milinevska, OA; Samoilenko, ОА; Shlyakhovenko, VA; Zaletok, SP	1

Reviews

2 review(s) available for arginine and eflornithine

Article	Year
Polyamines in microorganisms. Microbiological reviews, 1985, Volume: 49, Issue:1 Topics: Arginine; Aspergillus nidulans; Bacteria; Bacteriophages; Biodegradation, Environmental; Carboxy-Lyases; Eflornithine; Escherichia coli; Fungi; Guanine Nucleotides; Mutation; Neurospora crassa; Ornithine; Ornithine Decarboxylase; Physarum; Polyamines; Protein Biosynthesis; Saccharomyces cerevisiae; Spermine	1985
Polyamines, arginine and nitric oxide. Biochemical Society transactions, 1994, Volume: 22, Issue:4 Topics: Animals; Arginine; Biological Transport; Cell Line; Eflornithine; Endothelium, Vascular; Lipopolysaccharides; Mammals; Nitric Oxide; Polyamines	1994

Trials

1 trial(s) available for arginine and eflornithine

Article	Year
Phase I dose de-escalation trial of alpha-difluoromethylornithine in patients with grade 3 cervical intraepithelial neoplasia. Clinical cancer research : an official journal of the American Association for Cancer Research, 1998, Volume: 4, Issue:2 Topics: Administration, Oral; Adult; Antineoplastic Agents; Arginine; Biogenic Polyamines; Dose-Response Relationship, Drug; Drug Administration Schedule; Eflornithine; Enzyme Inhibitors; Female; Humans; Ornithine; Ornithine Decarboxylase; Uterine Cervical Dysplasia; Uterine Cervical Neoplasms	1998

Article

Year

Phase I dose de-escalation trial of alpha-difluoromethylornithine in patients with grade 3 cervical intraepithelial neoplasia.

Clinical cancer research : an official journal of the American Association for Cancer Research, 1998, Volume: 4, Issue:2

Topics: Administration, Oral; Adult; Antineoplastic Agents; Arginine; Biogenic Polyamines; Dose-Response Relationship, Drug; Drug Administration Schedule; Eflornithine; Enzyme Inhibitors; Female; Humans; Ornithine; Ornithine Decarboxylase; Uterine Cervical Dysplasia; Uterine Cervical Neoplasms

1998

Other Studies

62 other study(ies) available for arginine and eflornithine

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Dominant negative mutants of ornithine decarboxylase. The Journal of biological chemistry, 1992, Nov-15, Volume: 267, Issue:32 Topics: Amino Acid Sequence; Animals; Arginine; Eflornithine; Gene Expression; Genes; Genes, Dominant; Kinetics; Lysine; Mice; Mutagenesis, Site-Directed; Ornithine Decarboxylase; Plasmids; Polymerase Chain Reaction; Recombinant Proteins; Restriction Mapping	1992
Biochemical evidence for the presence of arginine decarboxylase activity in Trypanosoma cruzi. The Journal of parasitology, 1992, Volume: 78, Issue:2 Topics: Agmatine; Animals; Arginine; Carbon Dioxide; Carboxy-Lyases; Chromatography, High Pressure Liquid; Eflornithine; Trypanosoma cruzi	1992
DL-alpha-difluoromethylarginine inhibits intracellular Trypanosoma cruzi multiplication by affecting cell division but not trypomastigote-amastigote transformation. The Journal of parasitology, 1992, Volume: 78, Issue:3 Topics: Agmatine; Animals; Arginine; Cell Division; Eflornithine; Trypanosoma cruzi	1992
Inhibition of polyamine biosynthesis in Crithidia fasciculata by D,L-alpha-difluoromethylornithine and D,L-alpha-difluoromethylarginine. Molecular and biochemical parasitology, 1991, Volume: 46, Issue:1 Topics: Agmatine; Amidinotransferases; Animals; Arginase; Arginine; Carboxy-Lyases; Crithidia; Eflornithine; Kinetics; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine	1991
Biochemical and morphological effects of polyamine biosynthesis inhibitors on Trichophyton and Microsporum. Journal of medical and veterinary mycology : bi-monthly publication of the International Society for Human and Animal Mycology, 1991, Volume: 29, Issue:2 Topics: Arginase; Arginine; Carboxy-Lyases; Eflornithine; Microscopy, Electron; Microsporum; Ornithine Decarboxylase Inhibitors; Polyamines; Trichophyton	1991
The level of substrate ornithine can alter polyamine-dependent DNA synthesis following phorbolester stimulation of cultured hepatoma cells. Journal of cellular physiology, 1991, Volume: 149, Issue:1 Topics: Animals; Arginine; Blood; Clone Cells; Culture Media; DNA; Eflornithine; Insulin; Liver Neoplasms, Experimental; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured	1991
Polyamine metabolism in Pneumocystis carinii. The Journal of infectious diseases, 1991, Volume: 163, Issue:5 Topics: Animals; Arginine; Eflornithine; Lung; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Pentamidine; Pneumocystis; Polyamines; Putrescine; Rats; Spermidine; Spermine	1991
The interaction of trypanocidal drugs with polyamine and trypanothione metabolism. Biochemical Society transactions, 1990, Volume: 18, Issue:6 Topics: Animals; Arginine; Carboxy-Lyases; Crithidia; Eflornithine; Glutathione; Ornithine Decarboxylase Inhibitors; Polyamines; Spermidine; Trypanocidal Agents	1990
Biosynthetic arginine decarboxylase in phytopathogenic fungi. Life sciences, 1989, Volume: 44, Issue:17 Topics: Arginine; Ascomycota; Carboxy-Lyases; Eflornithine; Kinetics; Mitosporic Fungi; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Putrescine; Spermine; Xylariales	1989
Stimulus-secretion coupling of arginine-induced insulin release. Functional response of islets to L-arginine and L-ornithine. Biochimica et biophysica acta, 1989, Sep-19, Volume: 1013, Issue:2 Topics: Animals; Arginine; Calcium; Dose-Response Relationship, Drug; Eflornithine; Glucose; Inositol; Insulin; Insulin Secretion; Islets of Langerhans; Lysine; Ornithine; Oxidation-Reduction; Polyamines; Rats	1989
Stimulus-secretion coupling of arginine-induced insulin release. Effect of 2-aminoisobutyric acid upon ornithine decarboxylase activity and insulin secretion. Research communications in chemical pathology and pharmacology, 1989, Volume: 65, Issue:1 Topics: Amino Acids; Aminoisobutyric Acids; Animals; Arginine; Eflornithine; Enzyme Induction; Glucose; Glutamate Dehydrogenase; Insulin; Insulin Secretion; Ornithine Decarboxylase; Rats	1989
Ornithine aminotransferase activity, liver ornithine concentration and acute ammonia intoxication. Life sciences, 1989, Volume: 45, Issue:11 Topics: Acetates; Administration, Oral; Ammonia; Animals; Arginine; Creatinine; Eflornithine; Female; Injections, Intraperitoneal; Liver; Mice; Ornithine; Ornithine-Oxo-Acid Transaminase; Orotic Acid; Transaminases; Urea	1989
Uptake of alpha-difluoromethylornithine by Trypanosoma brucei brucei. Biochemical pharmacology, 1986, Jan-15, Volume: 35, Issue:2 Topics: Animals; Arginine; Biological Transport; Diffusion; Eflornithine; Lysine; Ornithine; Temperature; Trypanosoma brucei brucei	1986
Regulation of polyamine biosynthesis in tobacco. Effects of inhibitors and exogenous polyamines on arginine decarboxylase, ornithine decarboxylase, and S-adenosylmethionine decarboxylase. The Journal of biological chemistry, 1986, Jan-25, Volume: 261, Issue:3 Topics: Adenosylmethionine Decarboxylase; Arginine; Carboxy-Lyases; Cell Survival; Cells, Cultured; Eflornithine; Half-Life; Molecular Weight; Nicotiana; Ornithine; Ornithine Decarboxylase Inhibitors; Plants, Toxic; Polyamines	1986
A Trypanosoma brucei mutant resistant to alpha-difluoromethylornithine. Molecular and biochemical parasitology, 1987, Jan-02, Volume: 22, Issue:1 Topics: Animals; Arginine; Drug Resistance; Eflornithine; Mutation; Ornithine; Ornithine Decarboxylase; Putrescine; Trypanosoma brucei brucei	1987
Effect of dietary methionine, arginine and ornithine on the metabolism and accumulation of polyamines, S-adenosylmethionine and macromolecules in rat liver and skeletal muscle. Annals of nutrition & metabolism, 1987, Volume: 31, Issue:3 Topics: Amino Acids; Animals; Arginine; Body Weight; Diet; Eflornithine; Liver; Macromolecular Substances; Methionine; Muscles; Ornithine; Polyamines; Rats; Rats, Inbred Strains; S-Adenosylmethionine	1987
DL-alpha-difluoromethyl[3,4-3H]arginine metabolism in tobacco and mammalian cells. Inhibition of ornithine decarboxylase activity after arginase-mediated hydrolysis of DL-alpha-difluoromethylarginine to DL-alpha-difluoromethylornithine. The Biochemical journal, 1988, Oct-01, Volume: 255, Issue:1 Topics: Animals; Arginase; Arginine; Cattle; Eflornithine; Guanidines; Hydrolysis; In Vitro Techniques; Kinetics; Liver; Mice; Nicotiana; Ornithine Decarboxylase Inhibitors; Plants, Toxic; Substrate Specificity	1988
Susceptibility of Microsporum and Trichophyton species to suicide inhibitors of polyamine biosynthesis. Journal of medical and veterinary mycology : bi-monthly publication of the International Society for Human and Animal Mycology, 1988, Volume: 26, Issue:4 Topics: Antifungal Agents; Arginine; Arthrodermataceae; Carboxy-Lyases; Eflornithine; Microbial Sensitivity Tests; Microsporum; Ornithine Decarboxylase Inhibitors; Polyamines; Trichophyton	1988
Prevention of a plant disease by specific inhibition of fungal polyamine biosynthesis. Proceedings of the National Academy of Sciences of the United States of America, 1985, Volume: 82, Issue:20 Topics: Arginine; Basidiomycota; Eflornithine; Fabaceae; Ornithine; Ornithine Decarboxylase Inhibitors; Plant Diseases; Plants; Plants, Medicinal; Polyamines	1985
Inhibition of growth of Mycoplasma dispar by DL-alpha-difluoromethyllsine, a selective irreversible inhibitor of lysine decarboxylase, and reversal by cadaverine (1,5-diaminopentane). Biochemical and biophysical research communications, 1984, Nov-30, Volume: 125, Issue:1 Topics: Arginine; Cadaverine; Carboxy-Lyases; Cell Division; Diamines; Eflornithine; Lysine; Mycoplasma; Ornithine	1984
Restriction of bacterial growth by inhibition of polyamine biosynthesis by using monofluoromethylornithine, difluoromethylarginine and dicyclohexylammonium sulphate. The Biochemical journal, 1982, Nov-15, Volume: 208, Issue:2 Topics: Arginine; Cyclohexylamines; Depression, Chemical; Eflornithine; Escherichia coli; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Pseudomonas aeruginosa; Quaternary Ammonium Compounds	1982
Polyamines inhibit nitric oxide synthase in rat cerebellum. Neuroscience letters, 1994, Jul-04, Volume: 175, Issue:1-2 Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cells, Cultured; Cerebellum; Citrulline; Cytosol; Eflornithine; Kinetics; N-Methylaspartate; Neurons; Nitric Oxide Synthase; omega-N-Methylarginine; Polyamines; Putrescine; Rats; Spermidine; Spermine; Tritium	1994
Arginine and ornithine metabolizing enzymes in testosterone-induced hypertrophic mouse kidney. The international journal of biochemistry & cell biology, 1995, Volume: 27, Issue:3 Topics: Animals; Arginase; Arginine; Eflornithine; Enzyme Induction; Female; Folic Acid; Hypertrophy; Kidney; Male; Mice; Mice, Inbred Strains; Ornithine; Ornithine Decarboxylase; Ornithine-Oxo-Acid Transaminase; Putrescine; Quinazolines; Sex Factors; Testosterone	1995
Endothelial polyamine uptake: selective stimulation by L-arginine deprivation or polyamine depletion. The American journal of physiology, 1994, Volume: 266, Issue:3 Pt 1 Topics: Animals; Arginine; Biological Transport; Eflornithine; Endothelium, Vascular; Ornithine; Polyamines; Putrescine; Swine; Time Factors	1994
Polyamines in Trypanosoma cruzi. Biochemistry and molecular biology international, 1993, Volume: 30, Issue:3 Topics: Agmatine; Animals; Arginine; Carboxy-Lyases; Eflornithine; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Protozoan Proteins; Putrescine; Trypanosoma cruzi	1993
Healing of chronic gastric ulcerations by L-arginine. Role of nitric oxide, prostaglandins, gastrin and polyamines. Digestion, 1995, Volume: 56, Issue:6 Topics: Animals; Arginine; Chronic Disease; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Eflornithine; Gastrins; Indomethacin; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroglycerin; Polyamines; Prostaglandins; Rats; Rats, Wistar; Regional Blood Flow; Stomach; Stomach Ulcer; Vasodilator Agents	1995
Putrescine active uptake system in the Trypanosomatid Crithidia fasciculata. Biological chemistry Hoppe-Seyler, 1996, Volume: 377, Issue:4 Topics: Animals; Arginine; Biological Transport, Active; Crithidia; Diamines; Down-Regulation; Eflornithine; Enzyme Inhibitors; Ethylmaleimide; Ionophores; Kinetics; Polyamines; Putrescine; Sulfhydryl Compounds; Trypanocidal Agents; Up-Regulation	1996
Catecholamines are required for androgen-induced ODC expression but not for hypertrophy of mouse kidney. Biochimica et biophysica acta, 1997, May-27, Volume: 1356, Issue:3 Topics: Animals; Arginine; Catecholamines; Eflornithine; Enzyme Induction; Female; Gene Expression Regulation; Hypertrophy; Kidney; Mice; Ornithine; Ornithine Decarboxylase; Reserpine; RNA, Messenger; Testosterone	1997
Effect of ornithine in parenteral nutrition regimens on difluoromethylornithine-induced platelet suppression and changes in tumor polyamine content. Cancer investigation, 1998, Volume: 16, Issue:3 Topics: Animals; Arginine; Eflornithine; Hematocrit; Leukocyte Count; Male; Neoplasms, Experimental; Ornithine; Parenteral Nutrition; Platelet Count; Polyamines; Rats; Rats, Inbred F344	1998
Alpha-difluoromethylornithine (DFMO) as a potent arginase activity inhibitor in human colon carcinoma cells. Biochemical pharmacology, 1998, Apr-15, Volume: 55, Issue:8 Topics: Animals; Antineoplastic Agents; Arginase; Arginine; Cattle; Eflornithine; Enzyme Inhibitors; HT29 Cells; Humans; Liver; Ornithine; Ornithine Decarboxylase Inhibitors	1998
Intracellular polyamine levels are involved in NMDA-evoked nitric oxide production in chick retina cells. Journal of neurochemistry, 1999, Volume: 72, Issue:4 Topics: Animals; Arginine; Cells, Cultured; Chick Embryo; Citrulline; Cyclic GMP; Eflornithine; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glycine; N-Methylaspartate; NADPH Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase; Polyamines; Receptors, N-Methyl-D-Aspartate; Retina; Spermidine	1999
L-arginine metabolites regulate DNA synthesis and nitric oxide synthase activity in cultured human dermal microvascular endothelial cells--potential positive and negative regulators of angiogenesis derived from L-arginine. Cancer investigation, 1999, Volume: 17, Issue:4 Topics: Arginine; Biogenic Polyamines; Blotting, Western; Cell Survival; Cells, Cultured; DNA; Eflornithine; Endothelium, Vascular; Enzyme Inhibitors; Humans; Neovascularization, Physiologic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Ornithine Decarboxylase Inhibitors; Skin; Trypan Blue	1999
Arginine decarboxylase in Trypanosoma cruzi, characteristics and kinetic properties. Cellular and molecular biology (Noisy-le-Grand, France), 1999, Volume: 45, Issue:4 Topics: Animals; Arginine; Carboxy-Lyases; Culture Media; Eflornithine; Enzyme Activation; Enzyme Inhibitors; Kinetics; Ornithine Decarboxylase; Polyamines; Serum Albumin, Bovine; Trypanosoma cruzi	1999
Polyamines regulate serine/threonine protein phosphatases in insulin-secreting cells. Pancreas, 2000, Volume: 20, Issue:1 Topics: Arginine; Eflornithine; Enzyme Activation; Enzyme Inhibitors; Histones; Humans; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Okadaic Acid; Pancreatic Neoplasms; Phosphoprotein Phosphatases; Phosphorylation; Polyamines; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Putrescine; Spermidine; Spermine; Tumor Cells, Cultured	2000
Effect of inhibitors of polyamine biosynthesis on gibberellin-induced internode growth in light-grown dwarf peas. Plant & cell physiology, 1986, Volume: 27, Issue:2 Topics: Arginine; Carboxy-Lyases; Cycloheximide; Dactinomycin; Eflornithine; Enzyme Inhibitors; Gibberellins; Pisum sativum; Plant Growth Regulators; Polyamines; Protein Synthesis Inhibitors; Putrescine; RNA, Plant; Spermidine	1986
Arginine decarboxylase as the source of putrescine for tobacco alkaloids. Phytochemistry, 1986, Volume: 25, Issue:1 Topics: Alkaloids; Arginine; Carboxy-Lyases; Eflornithine; Enzyme Inhibitors; Nicotiana; Nicotine; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Plants, Toxic; Putrescine; Pyrrolidines	1986
Protection of wheat against leaf and stem rust and powdery mildew diseases by inhibition of polyamine metabolism. Plant science : an international journal of experimental plant biology, 1987, Volume: 51 Topics: Arginine; Carboxy-Lyases; Eflornithine; Fungi; Ornithine Decarboxylase Inhibitors; Plant Diseases; Polyamines; Triticum	1987
In vivo inhibition of polyamine biosynthesis and growth in tobacco ovary tissues. Plant & cell physiology, 1985, Volume: 26, Issue:8 Topics: Adenosylmethionine Decarboxylase; Arginine; Carboxy-Lyases; Eflornithine; Enzyme Inhibitors; Mitoguazone; Nicotiana; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Plants, Toxic; Polyamines; Putrescine; Spermidine; Spermine	1985
Effect of polyamine biosynthetic inhibitors on alkaloids and organogenesis in tobacco callus cultures. Plant cell, tissue and organ culture, 1987, Volume: 9 Topics: Arginine; Biomass; Carboxy-Lyases; Culture Techniques; Cyclohexylamines; Eflornithine; Enzyme Inhibitors; Nicotiana; Nicotine; Ornithine Decarboxylase Inhibitors; Plant Roots; Plants, Toxic; Polyamines; Putrescine; Spermidine; Spermidine Synthase	1987
Polyamine levels as related to growth, differentiation and senescence in protoplast-derived cultures of Vigna aconitifolia and Avena sativa. Plant growth regulation, 1985, Volume: 3 Topics: Arginine; Avena; Carboxy-Lyases; Cell Differentiation; Cell Division; Cells, Cultured; Cellular Senescence; Chlorophyll; Cyclohexylamines; Eflornithine; Enzyme Inhibitors; Fabaceae; Ornithine Decarboxylase Inhibitors; Plant Proteins; Plants, Medicinal; Polyamines; Protoplasts; Putrescine; Spermidine; Spermidine Synthase	1985
Polyamines and the integrity of the plant body. Acta Universitatis Agriculturae. Facultas agronomica. Vysoka skola zemedelska v Brne. Fakulta agronomicka, 1985, Volume: 33, Issue:3 Topics: Arginine; Carboxy-Lyases; Eflornithine; Ornithine Decarboxylase; Plant Cells; Plant Physiological Phenomena; Plants; Polyamines; Putrescine; Spermidine; Spermine	1985
The effects of some polyamine biosynthetic inhibitors on growth and morphology of phytopathogenic fungi. Plant & cell physiology, 1985, Volume: 26, Issue:4 Topics: Arginine; Carboxy-Lyases; Eflornithine; Enzyme Inhibitors; Mitosporic Fungi; Ornithine Decarboxylase Inhibitors; Plant Diseases; Polyamines; Putrescine; Rhizoctonia; Spermidine	1985
Differential regulation of nitric oxide synthase-2 and arginase-1 by type 1/type 2 cytokines in vivo: granulomatous pathology is shaped by the pattern of L-arginine metabolism. Journal of immunology (Baltimore, Md. : 1950), 2001, Dec-01, Volume: 167, Issue:11 Topics: Animals; Arginase; Arginine; Cells, Cultured; Disease Models, Animal; Eflornithine; Enzyme Activation; Enzyme Induction; Enzyme Inhibitors; Female; Granuloma; Interleukin-12; Liver; Liver Cirrhosis; Lung Diseases, Parasitic; Macrophage Activation; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Mycobacterium avium; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Ornithine Decarboxylase Inhibitors; Ovum; Proline; Schistosomiasis mansoni; Th1 Cells; Th2 Cells; Tuberculosis; Up-Regulation	2001
The effect of polyamine biosynthesis inhibition on growth and differentiation of the phytopathogenic fungus Sclerotinia sclerotiorum. Antonie van Leeuwenhoek, 2001, Volume: 80, Issue:3-4 Topics: Arginine; Ascomycota; Biogenic Polyamines; Cyclohexylamines; Eflornithine; Enzyme Inhibitors; Germination; Mitoguazone; Ornithine Decarboxylase Inhibitors; Plants; Spores, Fungal	2001
Effects of ornithine 2-oxoglutarate on neutrophils in stressed rats: evidence for the involvement of nitric oxide and polyamines. Clinical science (London, England : 1979), 2002, Volume: 102, Issue:3 Topics: Animals; Arginine; Chemotaxis, Leukocyte; Dexamethasone; Eflornithine; Enzyme Inhibitors; Glutamate-Ammonia Ligase; Glutamine; Hydrogen Peroxide; Isothiuronium; Male; Methionine Sulfoximine; Neutrophils; Nitric Oxide; Nitric Oxide Synthase; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Rats; Rats, Sprague-Dawley; Respiratory Burst; Stress, Psychological	2002
Involvement of polyamines in root development at low temperature in the subantarctic cruciferous species Pringlea antiscorbutica. Journal of experimental botany, 2002, Volume: 53, Issue:373 Topics: Acclimatization; Agmatine; Antarctic Regions; Arginine; Brassicaceae; Carboxy-Lyases; Cold Temperature; Drug Interactions; Eflornithine; Germination; Glutarates; Mitoguazone; Ornithine Decarboxylase; Plant Roots; Plant Shoots; Polyamines; Putrescine; Seeds; Spermidine; Spermine	2002
Ischemia-reperfusion selectively impairs nitric oxide-mediated dilation in coronary arterioles: counteracting role of arginase. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2003, Volume: 17, Issue:15 Topics: Adenosine; Animals; Arginase; Arginine; Arterioles; Coronary Vessels; Culture Techniques; Eflornithine; Enzyme Inhibitors; Models, Biological; Myocardial Reperfusion Injury; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Serotonin; Swine; Vasodilation; Vasodilator Agents	2003
Protective role of arginase in a mouse model of colitis. Journal of immunology (Baltimore, Md. : 1950), 2004, Aug-01, Volume: 173, Issue:3 Topics: Animals; Arginase; Arginine; Boronic Acids; Citrobacter rodentium; Colitis; Eflornithine; Enterobacteriaceae Infections; Enzyme Induction; Enzyme Inhibitors; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Ornithine; Ornithine Decarboxylase; Polyamines	2004
Albumin stimulates cell growth, l-arginine transport, and metabolism to polyamines in human proximal tubular cells. Kidney international, 2005, Volume: 67, Issue:5 Topics: Arginase; Arginine; Base Sequence; Biological Transport, Active; Cell Division; Cell Line; Eflornithine; Enzyme Inhibitors; Gene Expression; Homeostasis; Humans; Kidney Tubules, Proximal; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Recombinant Proteins; RNA, Messenger; Serum Albumin; Up-Regulation	2005
Role of polyamines derived from arginine in differentiation and proliferation of human blood cells. Biological & pharmaceutical bulletin, 2006, Volume: 29, Issue:2 Topics: Antigens, CD34; Arginine; Biogenic Polyamines; Biological Transport; Blood Cells; Cell Differentiation; Cell Proliferation; Culture Media; Eflornithine; Enzyme Inhibitors; Fetal Blood; Humans; K562 Cells; Ornithine Decarboxylase	2006
Spermine-induced morphogenesis and effect of partial immersion system on the shoot cultures of banana. Applied biochemistry and biotechnology, 2008, Volume: 151, Issue:2-3 Topics: Agriculture; Arginine; Eflornithine; Morphogenesis; Musa; Plant Shoots; Putrescine; Spermidine; Spermine	2008
The vascular effects of different arginase inhibitors in rat isolated aorta and mesenteric arteries. British journal of pharmacology, 2009, Volume: 156, Issue:1 Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginase; Arginine; Boronic Acids; Eflornithine; Endothelium, Vascular; In Vitro Techniques; Male; Mesenteric Arteries; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Tachyphylaxis; Valine; Vasodilator Agents	2009
Effects of arginase inhibitors on the contractile and relaxant responses of isolated human penile erectile tissue. World journal of urology, 2009, Volume: 27, Issue:6 Topics: Adult; Arginase; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Eflornithine; Enzyme Inhibitors; Humans; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Nitric Oxide; Organ Culture Techniques; Penile Erection; Penis; Sex Reassignment Procedures; Young Adult	2009
Agmatine, an endogenous imidazoline receptor ligand modulates ethanol anxiolysis and withdrawal anxiety in rats. European journal of pharmacology, 2010, Jul-10, Volume: 637, Issue:1-3 Topics: Agmatine; Animals; Anti-Anxiety Agents; Anxiety; Arginine; Biguanides; Brain; Clonidine; Dose-Response Relationship, Drug; Eflornithine; Ethanol; Guanidines; Imidazoles; Imidazoline Receptors; Ligands; Maze Learning; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome	2010
Repeated agmatine treatment attenuates nicotine sensitization in mice: modulation by alpha2-adrenoceptors. Behavioural brain research, 2010, Dec-01, Volume: 213, Issue:2 Topics: Agmatine; Animals; Arginine; Biguanides; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Eflornithine; Enzyme Inhibitors; Guanidines; Idazoxan; Male; Mice; Motor Activity; Nicotine; Receptors, Adrenergic, alpha-2; Yohimbine	2010
Cells derived from normal or cancer breast tissue exhibit different growth properties when deprived of arginine. Medical oncology (Northwood, London, England), 2012, Volume: 29, Issue:4 Topics: Arginine; Breast; Breast Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cellular Senescence; Eflornithine; Female; Humans	2012
Arginine enhances embryo implantation in rats through PI3K/PKB/mTOR/NO signaling pathway during early pregnancy. Reproduction (Cambridge, England), 2013, Volume: 145, Issue:1 Topics: Androstadienes; Animals; Arginine; Dietary Supplements; Eflornithine; Embryo Implantation; Female; Models, Animal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Pregnancy; Pregnancy, Animal; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases; Uterus; Wortmannin	2013
Evidences for the agmatine involvement in antidepressant like effect of bupropion in mouse forced swim test. Pharmacology, biochemistry, and behavior, 2013, Volume: 107 Topics: Agmatine; Animals; Antidepressive Agents; Arginine; Benzofurans; Biguanides; Bupropion; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Eflornithine; Guanidines; Idazoxan; Imidazoles; Immobility Response, Tonic; Injections, Intraventricular; Male; Mice; Motor Activity	2013
Chlamydia trachomatis inhibits inducible NO synthase in human mesenchymal stem cells by stimulating polyamine synthesis. Journal of immunology (Baltimore, Md. : 1950), 2014, Sep-15, Volume: 193, Issue:6 Topics: Arginine; Cells, Cultured; Chlamydia Infections; Chlamydia trachomatis; Eflornithine; Enzyme Inhibitors; Female; Humans; Mesenchymal Stem Cells; Nitric Oxide Synthase Type II; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Peroxynitrous Acid; Polyamines; RNA Interference; RNA, Messenger; RNA, Small Interfering; Up-Regulation	2014
Arginine deprivation and immune suppression in a mouse model of Alzheimer's disease. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015, Apr-15, Volume: 35, Issue:15 Topics: Age Factors; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Antigens, CD; Arginine; Brain; Disease Models, Animal; Disease Progression; Eflornithine; Humans; Immunologic Factors; Maze Learning; Memory, Short-Term; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microarray Analysis; Microglia; Mutation; Nitric Oxide Synthase Type II; Ornithine Decarboxylase Inhibitors	2015
Effect of polyamine metabolism inhibitors on Lewis lung carcinoma growth and metastasis. Experimental oncology, 2015, Volume: 37, Issue:2 Topics: Animals; Arginase; Arginine; Carcinoma, Lewis Lung; Cell Line, Tumor; Drug Screening Assays, Antitumor; Eflornithine; Female; Lung Neoplasms; Mice, Inbred C57BL; Neoplasm Transplantation; Tumor Burden	2015