Compounds > arginine

arginine and debrisoquin

arginine has been researched along with debrisoquin in 3 studies

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arvela, P; Mustajoki, P; Mustajoki, S; Pelkonen, O; Rautio, A1
Clement, B; Schultze-Mosgau, MH; Wohlers, H1
Allorge, D; Blaney, FE; Bréant, D; Broly, F; Cauffiez, C; Chevalier, D; Chowdry, J; Ellis, SW; Harlow, J; Lhermitte, M; Lo-Guidice, JM; Tucker, GT1

Other Studies

3 other study(ies) available for arginine and debrisoquin

ArticleYear
Effects of heme arginate on cytochrome P450-mediated metabolism of drugs in patients with variegate porphyria and in healthy men.
    Clinical pharmacology and therapeutics, 1994, Volume: 56, Issue:1

    Topics: Adult; Arginine; Caffeine; Coumarins; Cytochrome P-450 Enzyme System; Debrisoquin; Female; Heme; Humans; Isoenzymes; Lidocaine; Male; Middle Aged; Porphyrias, Hepatic; Reference Values

1994
Cytochrome P450 dependent N-hydroxylation of a guanidine (debrisoquine), microsomal catalysed reduction and further oxidation of the N-hydroxy-guanidine metabolite to the urea derivative. Similarity with the oxidation of arginine to citrulline and nitric
    Biochemical pharmacology, 1993, Dec-14, Volume: 46, Issue:12

    Topics: Animals; Arginine; Catalysis; Citrulline; Cytochrome P-450 Enzyme System; Debrisoquin; Female; Hydrogen-Ion Concentration; Hydroxylation; Kinetics; Male; Microsomes, Liver; Nitric Oxide; Oxidation-Reduction; Rabbits; Rats; Rats, Wistar; Species Specificity; Swine; Urea

1993
Functional analysis of CYP2D6.31 variant: homology modeling suggests possible disruption of redox partner interaction by Arg440His substitution.
    Proteins, 2005, May-01, Volume: 59, Issue:2

    Topics: Amino Acid Substitution; Arginine; Cloning, Molecular; Cytochrome P-450 CYP2D6; Debrisoquin; Dextromethorphan; Gene Frequency; Genetic Variation; Genotype; Histidine; Humans; Kinetics; Microsomes; Oxidation-Reduction; Phenotype; Polymerase Chain Reaction; Recombinant Proteins; Saccharomyces cerevisiae; Substrate Specificity

2005