arginine and cyclosporine

arginine has been researched along with cyclosporine in 103 studies

Research

Studies (103)

TimeframeStudies, this research(%)All Research%
pre-19901 (0.97)18.7374
1990's50 (48.54)18.2507
2000's35 (33.98)29.6817
2010's17 (16.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Farrand, SK; Hamada, SE1
Hoffman, RA; Langrehr, JM; Lee, TK; Müller, AR; Schraut, WH; Simmons, RL1
Boyle, JG; Fenn, JB; Whitehouse, CM1
Badger, AM; Bugelski, PJ; Kaplan, JM; Newman-Tarr, T; Olivera, DL; Ruggieri, EV1
Bartlett, ST; Curry, DL; Gillison, SL1
Berkenboom, G; Fang, ZY; Fontaine, J; Goldman, M; Unger, P1
Alexander, JW; Levy, AE1
Bonfoco, E; Ceccatelli, S; Manzo, L; Nicotera, P1
Amore, A; Bussolino, F; Cacace, G; Costamagna, C; Ghigo, D; Gianoglio, B; Mazzucco, G; Peruzzi, L; Picciotto, G; Porcellini, MG1
Barker, CV; Curtis, JJ; Gaston, RS; Sanders, PW; Schlessinger, SD; Warnock, DG1
Badalamenti, S; Como, G; Finazzi, S; Galmarini, D; Paone, G; Ponticelli, C; Tarantino, A; Viganò, E1
Pittelkow, MR; Robertson, RP; Seaquist, ER; Teuscher, AU1
Chatterjee, K; Chou, TM; De Groot, CJ; DeMarco, T; MacGregor, JS; Sudhir, K; Taylor, RN; Yock, PG1
Alvarado, JA; Bobadilla, NA; Franco, M; García-Torres, R; Herrera-Acosta, J; López, P; Mendoza, S; Tapia, E1
Conger, JD; Kim, GE; Robinette, JB1
Caramelo, CA; Casado, S; Gallego, MJ; García Villalón, AL; García, JL; Garrón, MP; Hernando, L; López Farre, AJ1
Robertson, RP; Seaquist, ER; Teuscher, AU1
Barat, A; Caramelo, CA; Casado, S; Gallego, MJ; Grandes, SM; Hernando, L; Lopez Farre, A; Monton, M; Riesco, A1
Brown, MR; De Nicola, L; Gabbai, FB; Thomson, SC; Wead, LM1
Barthelmebs, M; Billing, A; Fabre, M; Grima, M; Hofner, M; Imbs, JL; Krieger, JP; Stephan, D1
Andoh, TF; Bennett, WM; Gardner, MP; Houghton, DC; Lindsley, J1
Choi, KH; Han, DS; Kang, BS; Kang, SW; Kim, DH; Kim, HS; Lee, HY; Lee, YH1
Akiyama, K; Bing, RJ; Cannavino, C; Grant, P; Horstman, D; Suzuki, H; Wolf, WP1
Assan, R; Boitard, C; Deschamps, I; Jos, J; Laborde, K; Rakotoambinina, B; Robert, JJ; Timsit, J1
Carrier, M; Khalil, A; Latour, JG; Pelletier, LC1
Foegh, ML; Katz, N; Kodama, T; Lou, H; Ramwell, P; Wang, YN1
Assis, SM; Monteiro, JL; Seguro, AC1
Benet, LZ; Berg-Candolfi, M; Candolfi, E1
Bernardi, P; Eriksson, O; Fontaine, E; Petronilli, V1
Andrés, A; Campo, C; García-Robles, R; Lahera, V; Morales, JM; Praga, M; Rodicio, JL; Ruilope, LM1
Carrier, M; Dupuis, J; Mathieu, P; Pelletier, LC; Ryan, J1
Andoh, TF; Bennett, WM; Gardner, MP1
Andoh, TF; Bennett, WM; Couser, WG; Johnson, RJ; Pichler, RH; Shankland, SJ; Thomas, SE1
Keiser, HR; Oriji, GK2
Bartholomeusz, B; Hardy, KJ; Nelson, AS; Phillips, PA1
Dolinski, K; Heitman, J; Maier, P; Schmid, FX; Scholz, C1
Eichler, HG; Fuchs, C; Koller-Strametz, J; Laufer, G; Mensik, C; Putz, D; Schmetterer, L; Wisser, W; Wolzt, M1
Alexander, JW; Babcock, GF; Custer, DA; Gibson, SW; Ogle, CK; Valente, JF1
Akiguchi, I; Tomimoto, H1
Ardissino, G; Claris-Appiani, A; Daccò, V; Ghio, L; Testa, S; Tirelli, AS; Zhang, XZ1
Oriji, GK1
Choi, KC; Kang, DG; Kim, NH; Kim, SW; Kook, H; Lee, J1
Andreucci, VE; De Nicola, L; Nappi, F; Sabbatini, M; Sansone, G; Uccello, F1
Alexander, JW; Babcock, GF; Custer, DA; Frede, S; Gibson, SW; Li, BG; Ogle, CK; Valente, JF1
Andoh, TF; Bennett, WM; Shihab, FS; Yi, H1
Garlington, S; Khavari, PA; Kirschberg, T; Kreider, E; Lin, Q; McGrane, PL; Rothbard, JB; Wender, PA1
Clementi, G; Cutuli, VM; Fiore, CE; Messina, R; Pennisi, P; Prato, A1
Chiu, SC; Fu, E; Liu, D; Tz-Chong, C1
Amico-Roxas, M; Caruso, A; Clementi, G; Cutuli, VM; Fiore, CE; Mangano, NG; Matera, M; Pennisi, P; Prato, A1
Charpie, JR; Crowley, DC; D'Alecy, L; Goldberg, CS; Gomez, CA1
Finckenberg, P; Lassila, M; Moilanen, E; Nurminen, ML; Riutta, A; Salmenperä, P; Santisteban, J; Vapaatalo, H; Virtanen, I1
Azevedo, I; Keating, E; Martel, F1
Ardissino, G; Claris-Appiani, A; Colombo, D; Daccò, V; Ghio, L; Pace, E; Testa, S; Tirelli, AS; Zhang, XZ1
Dyer, PA; Haworth, SE; Hull, PS; Irwin, CR; James, JA; Linden, GJ; Marley, JJ; Maxwell, AP; McNamee, P; Middleton, D; Poulton, KV; Short, CD1
Bohdanecká, M; Bubenícek, P; Kazdová, L; Matl, I; Skibová, J; Táborský, P; Teplan, V; Veselá, J1
Levi, M; Moons, AH; Peters, RJ1
Ishii, M; Kiuchi, Y; Shimizu, S; Shiota, K; Yamamoto, S; Yamamoto, T1
Dehpour, AR; Homayoun, H; Khavandgar, S1
Al-Majed, A; Al-Rikabi, A; Daba, MH; Gado, A; Mansour, M1
Dehpour, AR; Homayoun, H; Khavandgar, S; Namiranian, K1
Dean, SK; Keogh, GW; Roberts, S; Scott, H; Tuch, BE1
Fujimura, A; Nishiki, K; Purkerson, JM; Schwartz, GJ; Tsuruoka, S; Wakaumi, M; Yamamoto, H1
Endoh, M; Ikegaya, N; Kumagai, H; Odamaki, M1
Berne, C; Felldin, M; Foss, A; Källen, R; Korsgren, O; Moberg, L; Nilsson, B; Olsson, A; Salmela, K; Tibell, A; Tufveson, G1
El-Gowilly, SM; El-Mas, MM; Mohy El-Din, MM; Sharabi, FM1
Davis, NA; Inman, SR; Lukaszek, VA; Mazzone, ME; Olson, KM; Yoder, KN1
Chander, V; Chopra, K1
Bernardi, P; Costantini, P; Eriksson, O; Franck, M; Greci, L; Johans, C; Johans, M; Kinnunen, PK; Liobikas, J; Milanesi, E; Panagiotaki, M; Principato, G1
Bay, A; Eşrefoğlu, M; Kuruş, M; Oztürk, F1
Acikel, C; Aslan, I; Bozlar, U; Caglar, K; Cakir, E; Erbil, K; Eyileten, T; Oguz, Y; Ozcan, O; Ozgurtas, T; Saglam, M; Sonmez, A; Vural, A; Yenicesu, M; Yilmaz, MI1
Alexander, JW; Alloway, R; Austin, J; Buell, JF; Cardi, M; Fidler, JP; Goel, S; Goodman, HR; Hanaway, M; Huang, S; Munda, R; Roy-Chaudhury, P; Safdar, S; Susskind, B; Trofe, J; Woodle, ES1
Blanton, A; Hercule, H; Nsaif, R; Oyekan, A1
Esrefoglu, M; Karabulut, AB; Kaya, M; Kurus, M; Otlu, A; Sogutlu, G1
Carlsson, U; Hammarström, P; Moparthi, SB1
Kumar, A; Kumar, P1
Di Marco, P; Doutreleau, S; Geny, B; Lonsdorfer, E; Piquard, F; Richard, R; Rouyer, O1
Abd-Elrahman, KS; Abdel-Galil, AG; El-Gowelli, HM; El-Mas, MM; Saad, EI1
El-Dayem, WA; Eladl, M; Elgalaly, H; Kamel, M; Maarouf, AM; Radwan, M; Salem, EA; Salem, NA1
Fletcher, JS; Kordys, J; Lockyer, NP; Piwowar, AM; Vickerman, JC; Winograd, N1
Drozdzik, M; Dziewanowski, K; Kozak, M; Kurzawski, M; Lapczuk, J; Lipski, M; Wajda, A1
Akay, OM; Bal, C; Gulbas, Z; Sahin, G; Yalcin, AU1
Akyuz, F; Birdane, A; Degirmenci, NA; Musmul, A; Ozkurt, S; Sahin, G; Tek, M; Tekin, N; Temiz, G; Yalcin, AU1
Bahry, D; Ben Tur, O; Chernichovski, T; Chernin, G; Grupper, A; Levi, S; Pri-Paz, Y; Schwartz, IF; Shashar, M1
Chalvignac, V; Lacarelle, B; Mouly-Bandini, A; Picard, N; Sampol-Manos, E; Sanchez, R1
Gota, V; Mehta, M; Patel, K; Patil, A; Vavia, P1
Akay, OM; Bal, C; Gulbas, Z; Sahin, G; Uslu, S; Yalcin, AU1
Deng, J; Liu, C; Lv, H; Yin, L; Zhang, Z; Zhou, J1
Hewedy, WA; Mostafa, DK1
Boiocchi, M; Colussi, AM; De Appollonia, L; Freschi, A; Galligioni, E; Gigante, M; Sandrin, A; Sorio, R; Talamini, R; Toffoli, G1
Bertrand, R; Jenkins, J; Pommier, Y; Solary, E1
Gonzalez, FJ; Korzekwa, KR; Nemec, J; Relling, MV; Schuetz, EG; Schuetz, JD1
Hill, BT; Hosking, LK1
Budning, A; Chan, HS; DeBoer, G; Gallie, BL; Koren, G; Ling, V; Thiessen, JJ; Verjee, Z1
Boiocchi, M; Corona, G; Galligioni, E; Gigante, M; Sorio, R; Toffoli, G1
Budning, A; Chan, HS; DeBoer, G; Gallie, BL; Giesbrecht, E; Haddad, G; Hungerford, JL; Kingston, JE; Koren, G; Ling, V; O'Brien, JM; Thiessen, JJ; Verjee, Z1
Aita, P; Bertola, A; Boiocchi, M; Colussi, AM; Corona, G; Robieux, I; Sorio, R; Toffoli, G1
Au, WY; Chan, GC; Ha, SY; Hon, C; Ma, SK; Wong, KF1

Reviews

3 review(s) available for arginine and cyclosporine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[The role of immunologic reactions in the pathogenesis in Binswanger's disease; a clue to therapeutic approach].
    Rinsho shinkeigaku = Clinical neurology, 1999, Volume: 39, Issue:1

    Topics: Animals; Antithrombins; Arginine; Blood Coagulation Factors; Brain; Brain Ischemia; Cyclosporine; Dementia, Vascular; Humans; Immunosuppressive Agents; Neuroglia; Pipecolic Acids; Sulfonamides; Thrombin

1999
Tissue factor and coronary artery disease.
    Cardiovascular research, 2002, Feb-01, Volume: 53, Issue:2

    Topics: Acute Disease; Angioplasty, Balloon, Coronary; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Anticoagulants; Arginine; Aspirin; Coronary Artery Disease; Coronary Thrombosis; Cyclosporine; Endothelium, Vascular; Factor VIIa; Heparin, Low-Molecular-Weight; Hirudin Therapy; Humans; Hypolipidemic Agents; Leukocytes, Mononuclear; Muscle, Smooth, Vascular; Recombinant Proteins; Thrombin; Thromboplastin

2002

Trials

9 trial(s) available for arginine and cyclosporine

ArticleYear
Renal effects of L-arginine infusion in cyclosporine-treated transplant recipients.
    Transplantation proceedings, 1994, Volume: 26, Issue:5

    Topics: Arginine; Azathioprine; Cyclosporine; Glomerular Filtration Rate; Humans; Infusions, Intravenous; Kidney Transplantation; Reference Values; Renal Circulation

1994
Cyclosporin A does not delay insulin dependency in asymptomatic IDDM patients.
    Diabetes care, 1995, Volume: 18, Issue:11

    Topics: Adolescent; Adult; Arginine; Blood Glucose; C-Peptide; Cyclosporine; Diabetes Mellitus, Type 1; Female; Follow-Up Studies; Glucagon; Glucose Clamp Technique; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Immunosuppressive Agents; Insulin; Insulin Secretion; Islets of Langerhans; Male; Reference Values

1995
Renal hemodynamic effects of L-arginine and sodium nitroprusside in heart transplant recipients.
    Kidney international, 1999, Volume: 55, Issue:5

    Topics: Aged; Arginine; Blood Pressure; Chronic Disease; Cohort Studies; Cyclosporine; Glomerular Filtration Rate; Heart Transplantation; Humans; Immunosuppressive Agents; Injections, Intravenous; Kidney; Kidney Diseases; Male; Middle Aged; Nitric Oxide; Nitroprusside; Renal Circulation; Vasodilator Agents

1999
Renal and metabolic effects of L-arginine infusion in kidney transplant recipients.
    Clinical nephrology, 1999, Volume: 52, Issue:1

    Topics: Adolescent; Adult; Arginine; Child; Cyclic GMP; Cyclosporine; Female; Glomerular Filtration Rate; Graft Rejection; Hemodynamics; Humans; Immunosuppressive Agents; Infusions, Intravenous; Kidney Transplantation; Male; p-Aminohippuric Acid; Reference Values; Sodium; Vascular Resistance

1999
L-arginine supplementation in young renal allograft recipients with chronic transplant dysfunction.
    Clinical nephrology, 2001, Volume: 55, Issue:6

    Topics: Adolescent; Arginine; Child; Cyclosporine; Double-Blind Method; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Time Factors

2001
Effect of cyclosporine on teniposide pharmacokinetics and pharmacodynamics in patients with renal cell cancer.
    Anti-cancer drugs, 1995, Volume: 6, Issue:3

    Topics: Aged; Bilirubin; Carcinoma, Renal Cell; Cell Count; Cyclosporine; Female; Granulocytes; Humans; Kidney Neoplasms; Male; Middle Aged; Pilot Projects; Teniposide

1995
Cyclosporin A as a multidrug-resistant modulator in patients with renal cell carcinoma treated with teniposide.
    British journal of cancer, 1997, Volume: 75, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Renal Cell; Cyclosporine; Drug Interactions; Drug Resistance, Multiple; Female; Humans; Kidney Neoplasms; Male; Middle Aged; Teniposide

1997
Combining cyclosporin with chemotherapy controls intraocular retinoblastoma without requiring radiation.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1996, Volume: 2, Issue:9

    Topics: Antineoplastic Agents; Area Under Curve; Carboplatin; Child, Preschool; Cyclosporine; Drug Therapy, Combination; Enzyme Inhibitors; Humans; Hypophosphatemia; Infant; Infant, Newborn; Retinal Neoplasms; Retinoblastoma; Teniposide; Treatment Outcome; Vincristine; Weight Loss

1996
Effect of cyclosporin A on protein binding of teniposide in cancer patients.
    Anti-cancer drugs, 1999, Volume: 10, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Area Under Curve; Bilirubin; Blood Proteins; Carcinoma, Renal Cell; Cyclosporine; Drug Interactions; Female; Half-Life; Humans; Immunosuppressive Agents; Kidney Neoplasms; Male; Middle Aged; Protein Binding; Teniposide

1999

Other Studies

91 other study(ies) available for arginine and cyclosporine

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Diversity among B6 strains of Agrobacterium tumefaciens.
    Journal of bacteriology, 1980, Volume: 141, Issue:3

    Topics: Arginine; Bacteriophages; Ketoses; Lactose; Lysogeny; Plant Tumors; Plasmids; Rhizobium; Species Specificity

1980
Serum NO2-/NO3- from oxidative L-arginine metabolism: a possible marker for small bowel allograft rejection.
    Transplantation proceedings, 1992, Volume: 24, Issue:3

    Topics: Animals; Arginine; Biomarkers; Cyclosporine; Graft Rejection; Intestine, Small; Nitrates; Nitrites; Rats; Rats, Inbred ACI; Rats, Inbred Lew; Transplantation, Homologous; Transplantation, Isogeneic

1992
An ion-storage time-of-flight mass spectrometer for analysis of electrospray ions.
    Rapid communications in mass spectrometry : RCM, 1991, Volume: 5, Issue:9

    Topics: Arginine; Cyclosporine; Cytochrome c Group; Mass Spectrometry; Molecular Weight

1991
Inhibition of lymphoproliferative responses by SK&F 105685, a novel anti-arthritic agent.
    Journal of clinical & laboratory immunology, 1991, Volume: 36, Issue:4

    Topics: Animals; Arginine; Arthritis; Concanavalin A; Cyclosporine; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Indomethacin; Interleukin-2; Lymphocyte Activation; Male; omega-N-Methylarginine; Polyenes; Rats; Rats, Inbred Lew; Sirolimus; Spiro Compounds; Spleen; Time Factors; Tumor Cells, Cultured

1991
Inhibition by cyclosporine of insulin secretion--a beta cell-specific alteration of islet tissue function.
    Transplantation, 1991, Volume: 52, Issue:5

    Topics: Analysis of Variance; Animals; Arginine; Calcium; Cyclosporine; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Male; Organ Size; Radioimmunoassay; Rats; Rats, Inbred Strains; Somatostatin; Time Factors

1991
Prevention of cyclosporine A-induced vascular toxicity by pentoxifylline.
    Journal of cardiovascular pharmacology, 1991, Volume: 18, Issue:5

    Topics: Acetylcholine; Animals; Arginine; Colforsin; Cyclosporine; Endothelium, Vascular; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Neuromuscular Depolarizing Agents; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Pentoxifylline; Phenylephrine; Rats; Rats, Inbred Strains; Vascular Diseases

1991
Nutritional immunomodulation enhances cardiac allograft survival in rats treated with donor-specific transfusion and cyclosporine.
    Transplantation, 1995, Oct-27, Volume: 60, Issue:8

    Topics: Adjuvants, Immunologic; Animals; Arginine; Blood Transfusion; Cyclosporine; Diet; Drug Synergism; Fish Oils; Graft Rejection; Graft Survival; Heart Transplantation; Immunosuppressive Agents; Male; Rats; Rats, Inbred ACI; Rats, Inbred Lew; RNA

1995
Colchicine induces apoptosis in cerebellar granule cells.
    Experimental cell research, 1995, Volume: 218, Issue:1

    Topics: Amino Acid Oxidoreductases; Animals; Apoptosis; Arginine; Calcium; Cell Survival; Cells, Cultured; Cerebellum; Colchicine; Cyclosporine; Dizocilpine Maleate; DNA; Kinetics; Neurons; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Paclitaxel; Rats; Rats, Sprague-Dawley; tau Proteins; Time Factors; Tubulin

1995
A possible role for nitric oxide in modulating the functional cyclosporine toxicity by arginine.
    Kidney international, 1995, Volume: 47, Issue:6

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Creatinine; Cyclic GMP; Cyclosporine; Hemodynamics; Isoenzymes; Kidney; Male; Nitric Oxide; Nitric Oxide Synthase; Proteinuria; Rats; Rats, Inbred Lew; Renal Circulation; RNA, Messenger

1995
Cyclosporine inhibits the renal response to L-arginine in human kidney transplant recipients.
    Journal of the American Society of Nephrology : JASN, 1995, Volume: 5, Issue:7

    Topics: Adult; Amino Acids, Branched-Chain; Arginine; Cyclosporine; Female; Hemodynamics; Humans; Kidney; Kidney Transplantation; Male; Renal Circulation

1995
[The effect of long-term cyclosporin and prednisone therapy on insulin secretory reserve].
    Schweizerische medizinische Wochenschrift, 1994, Nov-12, Volume: 124, Issue:45

    Topics: Adult; Analysis of Variance; Arginine; Blood Glucose; Cyclosporine; Female; Humans; Insulin; Insulin Secretion; Male; Prednisone; Time Factors

1994
Cyclosporine impairs release of endothelium-derived relaxing factors in epicardial and resistance coronary arteries.
    Circulation, 1994, Volume: 90, Issue:6

    Topics: Acetylcholine; Animals; Arginine; Arteries; Coronary Circulation; Coronary Vessels; Cyclosporine; Dogs; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroglycerin; Pericardium; Vascular Resistance; Vasodilation

1994
Role of nitric oxide in renal hemodynamic abnormalities of cyclosporin nephrotoxicity.
    Kidney international, 1994, Volume: 46, Issue:3

    Topics: Animals; Arginine; Blood Pressure; Cyclosporine; Glomerular Filtration Rate; Hemodynamics; Kidney Diseases; Male; Nephrectomy; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Renal Circulation; Vasoconstriction

1994
Effects of ANG II, ETA, and TxA2 receptor antagonists on cyclosporin A renal vasoconstriction.
    The American journal of physiology, 1994, Volume: 267, Issue:3 Pt 2

    Topics: Angiotensin Receptor Antagonists; Animals; Arginine; Cyclosporine; Endothelins; Glomerular Filtration Rate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Receptors, Thromboxane; Renal Circulation; Vasoconstriction

1994
Mechanisms of the endothelial toxicity of cyclosporin A. Role of nitric oxide, cGMP, and Ca2+.
    Circulation research, 1994, Volume: 74, Issue:3

    Topics: Animals; Aorta; Arginine; Calcium; Cyclic GMP; Cyclosporine; Endothelium, Vascular; Femoral Artery; In Vitro Techniques; Male; Nitric Oxide; Rats; Rats, Wistar; Vasodilation

1994
Diminished insulin secretory reserve in diabetic pancreas transplant and nondiabetic kidney transplant recipients.
    Diabetes, 1994, Volume: 43, Issue:4

    Topics: Adult; Arginine; Arthritis; Blood Glucose; C-Peptide; Cyclosporine; Diabetes Mellitus, Type 1; Female; Glucose; Humans; Immunosuppressive Agents; Insulin; Insulin Secretion; Islets of Langerhans; Kidney Transplantation; Male; Pancreas Transplantation; Prednisone; Psoriasis; Transplantation, Homologous

1994
Blockade of endothelium-dependent responses in conscious rats by cyclosporin A: effect of L-arginine.
    The American journal of physiology, 1993, Volume: 264, Issue:3 Pt 2

    Topics: Acetylcholine; Animals; Arginine; Atrial Natriuretic Factor; Cyclosporine; Diuresis; Endothelium, Vascular; Guanosine Monophosphate; Male; Natriuresis; Nitroprusside; Rats; Rats, Wistar; Vasodilation

1993
Arginine feeding modifies cyclosporine nephrotoxicity in rats.
    The Journal of clinical investigation, 1993, Volume: 92, Issue:4

    Topics: Administration, Oral; Angiotensin II; Animals; Arginine; Capillaries; Cyclosporine; Glomerular Filtration Rate; Hydrostatic Pressure; Kidney; Kidney Glomerulus; Male; Nephrons; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Wistar; Regional Blood Flow; Vascular Resistance

1993
Endothelium-dependent relaxation in the isolated rat kidney: impairment by cyclosporine A.
    Journal of cardiovascular pharmacology, 1995, Volume: 26, Issue:6

    Topics: Animals; Arginine; Body Weight; Cholic Acids; Cyclosporine; Endothelium, Vascular; Immunosuppressive Agents; Indomethacin; Kidney; Male; NG-Nitroarginine Methyl Ester; Perfusion; Rats; Rats, Wistar; Vasodilation

1995
Clinically relevant doses and blood levels produce experimental cyclosporine nephrotoxicity when combined with nitric oxide inhibition.
    Transplantation, 1996, May-27, Volume: 61, Issue:10

    Topics: Animals; Arginine; Body Weight; Cyclosporine; Diet, Sodium-Restricted; Enzyme Inhibitors; Hemodynamics; Kidney Cortex; Kidney Diseases; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley

1996
L-arginine restores suppressed acetylcholine-induced endothelium-dependent vascular relaxation in cyclosporine A-treated rats.
    Transplantation proceedings, 1996, Volume: 28, Issue:3

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Cyclosporine; Endothelium, Vascular; Immunosuppressive Agents; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Polyethylene Glycols; Rats; Rats, Sprague-Dawley

1996
Effect of inhibitors of inducible form of nitric oxide synthase in infarcted heart muscle.
    Proceedings of the Association of American Physicians, 1996, Volume: 108, Issue:2

    Topics: Animals; Arginine; Cyclosporine; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanidines; Heart; Isothiuronium; Male; Myocardial Infarction; Myocardium; Nitric Oxide Synthase; Nitroarginine; Rabbits

1996
Cyclosporin A-induced coronary artery vasoconstriction through myogenic and endothelium-dependent mechanisms.
    Circulation, 1996, Nov-01, Volume: 94, Issue:9 Suppl

    Topics: Acetylcholine; Adenosine; Animals; Arginine; Coronary Circulation; Coronary Vessels; Cyclosporine; Dogs; Endothelium, Vascular; Female; Hemodynamics; Immunosuppressive Agents; Male; Muscle, Smooth, Vascular; Nitroglycerin; Vasoconstriction

1996
L-arginine prevents heart transplant arteriosclerosis by modulating the vascular cell proliferative response to insulin-like growth factor-I and interleukin-6.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 1996, Volume: 15, Issue:12

    Topics: Animals; Antineoplastic Agents; Aorta; Arginine; Coronary Artery Disease; Coronary Vessels; Cyclosporine; Graft Rejection; Heart Transplantation; Histocompatibility Antigens Class II; Hyperplasia; Immunosuppressive Agents; Insulin-Like Growth Factor I; Interleukin-6; Macrophages; Male; Nitric Oxide; Postoperative Complications; Rabbits; T-Lymphocytes; Transplantation, Homologous

1996
L-Arginine and allopurinol protect against cyclosporine nephrotoxicity.
    Transplantation, 1997, Apr-27, Volume: 63, Issue:8

    Topics: Allopurinol; Animals; Arginine; Cyclosporine; Enzyme Inhibitors; Glomerular Filtration Rate; Inulin; Kidney Diseases; Male; Nitrates; Nitric Oxide; Nitrites; Potassium; Rats; Xanthine Oxidase

1997
Suppression of intestinal and hepatic cytochrome P4503A in murine Toxoplasma infection. Effects of N-acetylcysteine and N(G)-monomethyl-L-arginine on the hepatic suppression.
    Xenobiotica; the fate of foreign compounds in biological systems, 1996, Volume: 26, Issue:4

    Topics: Acetylcysteine; Animals; Antibodies, Monoclonal; Arginine; Aryl Hydrocarbon Hydroxylases; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Erythromycin; Interferon-gamma; Intestinal Mucosa; Jejunum; Macrophages, Peritoneal; Male; Mice; Mice, Inbred CBA; Microsomes; Microsomes, Liver; Nitrites; Oxidoreductases, N-Demethylating; Toxoplasmosis, Animal

1996
Inhibition of the mitochondrial cyclosporin A-sensitive permeability transition pore by the arginine reagent phenylglyoxal.
    FEBS letters, 1997, Jun-16, Volume: 409, Issue:3

    Topics: Animals; Arginine; Calcium; Cyclosporine; Indicators and Reagents; Intracellular Membranes; Male; Mitochondria, Liver; Oxygen Consumption; Permeability; Phenylglyoxal; Rats; Rats, Wistar

1997
L-arginine reverses the antinatriuretic effect of cyclosporin in renal transplant patients.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1997, Volume: 12, Issue:7

    Topics: Adult; Arginine; Cyclosporine; Humans; Immunosuppressive Agents; Kidney; Kidney Transplantation; Male; Middle Aged; Natriuresis

1997
L-arginine prevents cyclosporin A-induced pulmonary vascular dysfunction.
    The Annals of thoracic surgery, 1997, Volume: 64, Issue:2

    Topics: Acetylcholine; Animals; Arginine; Atrial Function, Left; Blood Pressure; Bradykinin; Cyclooxygenase Inhibitors; Cyclosporine; Dogs; Endothelium, Vascular; Indomethacin; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroglycerin; Peptidyl-Dipeptidase A; Pulmonary Artery; Pulmonary Circulation; Substance P; Vasodilation; Vasodilator Agents

1997
Protective effects of dietary L-arginine supplementation on chronic cyclosporine nephrotoxicity.
    Transplantation, 1997, Nov-15, Volume: 64, Issue:9

    Topics: Animals; Arginine; Blood Pressure; Cyclosporine; Enzyme Inhibitors; Fibrosis; Glomerular Filtration Rate; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Vascular Diseases

1997
Accelerated apoptosis characterizes cyclosporine-associated interstitial fibrosis.
    Kidney international, 1998, Volume: 53, Issue:4

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Apoptosis; Arginine; Biotin; Cyclosporine; Deoxyuracil Nucleotides; DNA Fragmentation; Enzyme Inhibitors; Fibrosis; Hydralazine; Immunosuppressive Agents; Ischemia; Kidney; Losartan; Macrophages; Male; Nephritis, Interstitial; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Staining and Labeling

1998
Role of nitric oxide in cyclosporine A-induced hypertension.
    Hypertension (Dallas, Tex. : 1979), 1998, Volume: 32, Issue:5

    Topics: Animals; Aorta; Arginine; Blood Pressure; Bosentan; Cyclic GMP; Cyclosporine; Endothelin Receptor Antagonists; Enzyme Inhibitors; Hypertension; Immunosuppressive Agents; Male; Nitrates; Nitrites; Olive Oil; Penicillamine; Peptides, Cyclic; Plant Oils; Rats; Rats, Sprague-Dawley; Sulfonamides; Vasoconstriction

1998
Modulation of nitric oxide improves cyclosporin A-induced hypertension in rats and primates.
    Journal of human hypertension, 1998, Volume: 12, Issue:12

    Topics: Animals; Antihypertensive Agents; Arginine; Blood Pressure; Bosentan; Callithrix; Cyclosporine; Enzyme Inhibitors; Female; Hypertension; Immunosuppressive Agents; Male; Nitrates; Nitric Oxide; Nitrites; Nitroarginine; Rats; Rats, Wistar; Sulfonamides; Systole

1998
R73A and H144Q mutants of the yeast mitochondrial cyclophilin Cpr3 exhibit a low prolyl isomerase activity in both peptide and protein-folding assays.
    FEBS letters, 1999, Jan-29, Volume: 443, Issue:3

    Topics: Arginine; Binding Sites; Carrier Proteins; Chromatography; Chymotrypsin; Circular Dichroism; Cyclosporine; Escherichia coli Proteins; Histidine; Humans; Kinetics; Mitochondria; Mutation; Peptidylprolyl Isomerase; Protein Binding; Protein Folding; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Substrate Specificity; Tacrolimus

1999
The effect of nutritional immunomodulation on cardiac allograft survival in rats receiving mycophenolate mofetil, cyclosporine A, and donor-specific transfusion.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 1999, Volume: 18, Issue:3

    Topics: Adjuvants, Immunologic; Animals; Arginine; Blood Transfusion; Cyclosporine; Fatty Acids, Omega-3; Food, Formulated; Graft Survival; Heart Transplantation; Immunosuppressive Agents; Male; Mycophenolic Acid; Rats; Rats, Inbred ACI; Rats, Inbred Lew; RNA; Tissue Donors; Transplantation, Homologous

1999
Nitric oxide in cyclosporine A-induced hypertension: endothelin receptors gene expression.
    Prostaglandins, leukotrienes, and essential fatty acids, 1999, Volume: 61, Issue:1

    Topics: Animals; Aorta; Arginine; Cyclosporine; Gene Expression; Hypertension; Male; Nitrates; Nitric Oxide; Nitrites; Olive Oil; Plant Oils; Rats; Rats, Inbred SHR; Receptors, Endothelin; RNA, Messenger

1999
Effects of L-arginine on cyclosporin-induced alterations of vascular NO/cGMP generation.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1999, Volume: 14, Issue:11

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Cyclic GMP; Cyclosporine; In Vitro Techniques; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroprusside; Rats; Rats, Sprague-Dawley; Vasodilation; Vasodilator Agents

1999
Nitric oxide in cyclosporine A-induced hypertension: role of protein kinase C.
    American journal of hypertension, 1999, Volume: 12, Issue:11 Pt 1

    Topics: Acetylcholine; Animals; Antihypertensive Agents; Aorta, Thoracic; Arginine; Cyclic GMP; Cyclosporine; Endothelin Receptor Antagonists; Endothelins; Endothelium, Vascular; Hypertension; Immunosuppressive Agents; Male; Nitric Oxide; Protein Kinase C; Rats; Rats, Sprague-Dawley; Vasodilation; Vasodilator Agents

1999
Acute effects of rapamycin on glomerular dynamics: a micropuncture study in the rat.
    Transplantation, 2000, May-15, Volume: 69, Issue:9

    Topics: Animals; Arginine; Cyclosporine; Glomerular Filtration Rate; Hemodynamics; Immunosuppressive Agents; Insulin; Male; Nitric Oxide; Punctures; Rats; Sirolimus

2000
Nutritional immunomodulation leads to enhanced allograft survival in combination with cyclosporine A and rapamycin, but not FK506.
    Transplantation, 2000, May-27, Volume: 69, Issue:10

    Topics: Animals; Arginine; Cyclosporine; Diet; Dietary Supplements; Fish Oils; Graft Survival; Heart Transplantation; Immunosuppression Therapy; Immunosuppressive Agents; Male; Rats; Rats, Inbred ACI; Rats, Inbred Lew; RNA; Sirolimus; Tacrolimus; Transplantation, Homologous

2000
Effect of nitric oxide modulation on TGF-beta1 and matrix proteins in chronic cyclosporine nephrotoxicity.
    Kidney international, 2000, Volume: 58, Issue:3

    Topics: Animals; Arginine; Arterioles; Biglycan; Blood Pressure; Blotting, Northern; Chronic Disease; Collagen; Cyclosporine; Enzyme Inhibitors; Extracellular Matrix Proteins; Fibronectins; Fibrosis; Gene Expression; Glomerular Filtration Rate; Hyalin; Immunosuppressive Agents; Kidney Diseases; Kidney Glomerulus; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Plasminogen Activator Inhibitor 1; Proteoglycans; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transforming Growth Factor beta

2000
Conjugation of arginine oligomers to cyclosporin A facilitates topical delivery and inhibition of inflammation.
    Nature medicine, 2000, Volume: 6, Issue:11

    Topics: Administration, Topical; Animals; Arginine; Biological Transport; Biotinylation; Cyclosporine; Cyclosporins; Humans; Inflammation; Interleukin-2; Ionomycin; Jurkat Cells; Mice; Mice, Inbred BALB C; Molecular Structure; Prodrugs; Skin; Skin Absorption; Tetradecanoylphorbol Acetate

2000
L-arginine prevents bone loss and bone collagen breakdown in cyclosporin A-treated rats.
    European journal of pharmacology, 2000, Nov-24, Volume: 408, Issue:3

    Topics: Amino Acids; Animals; Arginine; Body Weight; Bone and Bones; Bone Density; Collagen; Cyclosporine; Male; NG-Nitroarginine Methyl Ester; Rats; Rats, Sprague-Dawley

2000
Ameliorated effect of L-arginine supplementation on gingival morphology in cyclosporin-treated rats.
    Journal of periodontology, 2000, Volume: 71, Issue:11

    Topics: Analysis of Variance; Animals; Arginine; Blood Pressure; Cyclosporine; Enzyme Inhibitors; Gingiva; Gingival Overgrowth; Immunosuppressive Agents; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric

2000
Role of soy diet and L-arginine in cyclosporin-A-induced osteopenia in rats.
    Pharmacology & toxicology, 2001, Volume: 88, Issue:1

    Topics: Animals; Arginine; Body Weight; Bone Density; Bone Diseases, Metabolic; Calcium; Cyclosporine; Diet; Disease Models, Animal; Drug Therapy, Combination; Immunosuppressive Agents; Injections, Intraperitoneal; Male; Pelvic Bones; Radiography; Rats; Rats, Sprague-Dawley; Soybean Proteins; Spine

2001
Effect of arginine on cyclosporine-induced systemic hypertension after cardiac transplantation in the young.
    The American journal of cardiology, 2001, Apr-01, Volume: 87, Issue:7

    Topics: Adolescent; Adult; Arginine; Blood Pressure; Case-Control Studies; Chromatography, High Pressure Liquid; Citrulline; Cyclosporine; Echocardiography; Female; Heart Transplantation; Humans; Hypertension; Immunosuppressive Agents; Infusions, Intravenous; Male; Ventricular Function, Left

2001
Vascular changes in cyclosporine A-induced hypertension and nephrotoxicity in spontaneously hypertensive rats on high-sodium diet.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2001, Volume: 52, Issue:1

    Topics: Acetylcholine; Animals; Arginine; Blood Pressure; Blood Vessels; Cells, Cultured; Cyclosporine; Heart; Heart Rate; Hypertension; Immunosuppressive Agents; Kidney; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroprusside; Norepinephrine; Organ Size; Oxidative Stress; Potassium Chloride; Rats; Rats, Inbred SHR; Sodium, Dietary; Vasoconstrictor Agents; Vasodilator Agents

2001
Effect of P-glycoprotein modulators on the human extraneuronal monoamine transporter.
    European journal of pharmacology, 2001, Jun-22, Volume: 422, Issue:1-3

    Topics: 1-Methyl-4-phenylpyridinium; Arginine; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Carrier Proteins; Cations; Cell Line; Cyclosporine; Daunorubicin; Dose-Response Relationship, Drug; Histidine; Humans; Organic Cation Transport Proteins; Rhodamine 123; Time Factors; Tritium; Tyramine; Verapamil; Vinblastine

2001
The influence of transforming growth factor-beta1 gene polymorphisms on the severity of gingival overgrowth associated with concomitant use of cyclosporin A and a calcium channel blocker.
    Journal of periodontology, 2001, Volume: 72, Issue:6

    Topics: Adult; Age Factors; Alleles; Analysis of Variance; Arginine; Calcium Channel Blockers; Chi-Square Distribution; Codon; Confidence Intervals; Cyclosporine; DNA; Female; Gene Expression Regulation; Genotype; Gingival Overgrowth; Heterozygote; Homozygote; Humans; Immunosuppressive Agents; Kidney Transplantation; Leucine; Logistic Models; Male; Odds Ratio; Polymorphism, Genetic; Proline; Transforming Growth Factor beta; Transforming Growth Factor beta1

2001
[Nitric oxide (NO) in a model of renal ischemia and cyclosporine toxicity].
    Casopis lekaru ceskych, 2001, Jun-05, Volume: 140, Issue:13

    Topics: Animals; Arginine; Cyclosporine; Immunosuppressive Agents; Ischemia; Kidney; Male; Nitric Oxide; Rats; Rats, Wistar; Vasodilator Agents

2001
Stimulation of tetrahydrobiopterin synthesis by cyclosporin A in mouse brain microvascular endothelial cells.
    The international journal of biochemistry & cell biology, 2002, Volume: 34, Issue:9

    Topics: Animals; Antioxidants; Arginine; Biopterins; Cerebrovascular Circulation; Cycloheximide; Cyclosporine; Endothelium, Vascular; GTP Cyclohydrolase; Immunosuppressive Agents; Mice; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Protein Synthesis Inhibitors

2002
Anticonvulsant effects of cyclosporin A on pentylenetetrazole-induced seizure and kindling: modulation by nitricoxidergic system.
    Brain research, 2002, Jun-07, Volume: 939, Issue:1-2

    Topics: Animals; Anticonvulsants; Arginine; Convulsants; Cyclosporine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanidines; Kindling, Neurologic; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pentylenetetrazole; Seizures

2002
Protective effect of L-arginine against nephrotoxicity induced by cyclosporine in normal rats.
    Pharmacological research, 2002, Volume: 45, Issue:6

    Topics: Animals; Arginine; Creatinine; Cyclosporine; Enzyme Inhibitors; Glutathione Peroxidase; Guanidines; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Tubules; Male; Nephritis, Interstitial; Nitric Oxide Synthase; Rats; Rats, Inbred Strains; Urea

2002
The effect of cyclosporin A on morphine tolerance and dependence: involvement of L-arginine/nitric oxide pathway.
    European journal of pharmacology, 2002, Sep-27, Volume: 452, Issue:1

    Topics: Analgesics, Opioid; Animals; Arginine; Cyclosporine; Drug Tolerance; Guanidines; Immunosuppressive Agents; Male; Mice; Morphine; Morphine Dependence; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Reaction Time

2002
Effect of immunosuppressive doses of cyclosporine on pancreatic beta cell function in pigs.
    American journal of veterinary research, 2002, Volume: 63, Issue:11

    Topics: Alanine Transaminase; Animals; Arginine; Bilirubin; Blood Glucose; C-Reactive Protein; Creatinine; Cyclosporine; Glucagon; Glucose Tolerance Test; Immunosuppressive Agents; Insulin; Islets of Langerhans; Kidney; Liver; Liver Function Tests; Serum Albumin; Swine

2002
Nitric oxide production modulates cyclosporin A-induced distal renal tubular acidosis in the rat.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 305, Issue:3

    Topics: Acidosis, Renal Tubular; Animals; Arginine; Blood Pressure; Body Weight; Creatine; Cyclosporine; Humans; Immunosuppressive Agents; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Protons; Rats; Rats, Wistar; Renal Circulation

2003
Factors involved in the development of hypertension induced by a low-protein diet in rats with renal injury.
    Kidney & blood pressure research, 2004, Volume: 27, Issue:1

    Topics: Animals; Arginine; Blood Pressure; Cyclosporine; Diet, Protein-Restricted; Dietary Supplements; Hypertension; Kidney; Kidney Diseases; Male; Nitrates; Nitric Oxide; Nitrites; Rats; Rats, Sprague-Dawley; Sucrose

2004
Nicotinamide inhibits tissue factor expression in isolated human pancreatic islets: implications for clinical islet transplantation.
    Transplantation, 2003, Nov-15, Volume: 76, Issue:9

    Topics: Arginine; Cells, Cultured; Chemokine CCL2; Cyclosporine; Enalapril; Gene Expression Regulation; Humans; Islets of Langerhans; Islets of Langerhans Transplantation; Kinetics; Niacinamide; Thromboplastin

2003
Relative roles of endothelial relaxing factors in cyclosporine-induced impairment of cholinergic and beta-adrenergic renal vasodilations.
    European journal of pharmacology, 2004, Mar-08, Volume: 487, Issue:1-3

    Topics: Acetylcholine; Animals; Arginine; Biological Factors; Cyclooxygenase Inhibitors; Cyclosporine; Dose-Response Relationship, Drug; Endothelium-Dependent Relaxing Factors; Enzyme Inhibitors; In Vitro Techniques; Isoproterenol; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Parasympathetic Nervous System; Phenylephrine; Potassium Channel Blockers; Prostaglandins; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Renal Circulation; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

2004
Simvastatin and L-arginine preserve renal function after ischemia/reperfusion injury.
    The American journal of the medical sciences, 2005, Volume: 329, Issue:1

    Topics: Animals; Arginine; Cyclosporine; Drug Therapy, Combination; Glomerular Filtration Rate; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunosuppressive Agents; Kidney Diseases; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Random Allocation; Rats; Rats, Wistar; Reperfusion Injury; Simvastatin

2005
Effect of molsidomine and L-arginine in cyclosporine nephrotoxicity: role of nitric oxide.
    Toxicology, 2005, Feb-28, Volume: 207, Issue:3

    Topics: Administration, Oral; Animals; Arginine; Cyclosporine; Dose-Response Relationship, Drug; Drinking; Drug Therapy, Combination; Enzyme Inhibitors; Immunosuppressive Agents; Injections, Subcutaneous; Kidney Diseases; Male; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Oxidative Stress; Rats; Water Supply

2005
Modification of permeability transition pore arginine(s) by phenylglyoxal derivatives in isolated mitochondria and mammalian cells. Structure-function relationship of arginine ligands.
    The Journal of biological chemistry, 2005, Apr-01, Volume: 280, Issue:13

    Topics: Animals; Arginine; Calcium; Cell Line, Tumor; Cyclosporine; HeLa Cells; Humans; Hydrogen Bonding; Intracellular Membranes; Ion Channels; Membrane Potentials; Mitochondria; Mitochondria, Liver; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Mitochondrial Swelling; Models, Chemical; Permeability; Phenylglyoxal; Protein Binding; Protein Conformation; Rats; Rats, Wistar; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Time Factors

2005
Protective effect of oral L-arginine supplementation on cyclosporine induced nephropathy in rats.
    International urology and nephrology, 2005, Volume: 37, Issue:3

    Topics: Animals; Arginine; Atrophy; Cyclosporine; Dietary Supplements; Female; Glomerular Filtration Rate; Immunosuppressive Agents; Kidney Diseases; Kidney Tubules; Necrosis; NG-Nitroarginine Methyl Ester; Rats; Rats, Sprague-Dawley

2005
Endothelial functions improve with decrease in asymmetric dimethylarginine (ADMA) levels after renal transplantation.
    Transplantation, 2005, Dec-27, Volume: 80, Issue:12

    Topics: Adult; Arginine; Biomarkers; Blood Glucose; Blood Pressure; C-Reactive Protein; Cohort Studies; Cyclosporine; Female; Humans; Immunosuppressive Agents; Kidney Failure, Chronic; Kidney Transplantation; Lipids; Living Donors; Male; Prospective Studies; Tacrolimus; Treatment Outcome

2005
Simultaneous corticosteroid avoidance and calcineurin inhibitor minimization in renal transplantation.
    Transplant international : official journal of the European Society for Organ Transplantation, 2006, Volume: 19, Issue:4

    Topics: Adrenal Cortex Hormones; Antilymphocyte Serum; Arginine; Calcineurin Inhibitors; Cyclosporine; Fatty Acids, Monounsaturated; Female; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged; Mycophenolic Acid; Pilot Projects; Rapeseed Oil; Sirolimus; T-Lymphocytes

2006
Nitric oxide/cytochrome P450 interactions in cyclosporin A-induced effects in the rat.
    Journal of hypertension, 2006, Volume: 24, Issue:9

    Topics: Amidines; Animals; Arginine; Blood Pressure; Bradykinin; Cyclosporine; Cytochrome P-450 Enzyme System; Endothelin-1; Hydroxyeicosatetraenoic Acids; Kidney; Male; Microsomes; Nitric Oxide; Nitroprusside; Phenylephrine; Rats; Rats, Sprague-Dawley; Triazoles

2006
Oral L-arginine protects against cyclosporine-induced hepatotoxicity in rats.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2008, Volume: 60, Issue:4-5

    Topics: Administration, Oral; Animals; Arginine; Cyclosporine; Enzyme Inhibitors; Female; Immunosuppressive Agents; Liver; Malondialdehyde; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley

2008
A nonessential role for Arg 55 in cyclophilin18 for catalysis of proline isomerization during protein folding.
    Protein science : a publication of the Protein Society, 2009, Volume: 18, Issue:2

    Topics: Arginine; Carbonic Anhydrase II; Catalytic Domain; Cyclophilin A; Cyclosporine; Escherichia coli; Humans; Isomerism; Kinetics; Mutation; Peptides; Protein Engineering; Protein Folding

2009
Neuroprotective effect of cyclosporine and FK506 against 3-nitropropionic acid induced cognitive dysfunction and glutathione redox in rat: possible role of nitric oxide.
    Neuroscience research, 2009, Volume: 63, Issue:4

    Topics: Acetylcholinesterase; Analysis of Variance; Animals; Arginine; Behavior, Animal; Brain; Cognition Disorders; Cyclosporine; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Glutathione; Glutathione Transferase; Male; Maze Learning; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitro Compounds; Oxidative Stress; Propionates; Rats; Rats, Wistar; Tacrolimus; Time Factors

2009
L-arginine supplementation improves exercise capacity after a heart transplant.
    The American journal of clinical nutrition, 2010, Volume: 91, Issue:5

    Topics: Arginine; Blood Pressure; Cyclosporine; Dietary Supplements; Double-Blind Method; Echocardiography; Endothelin-1; Endothelins; Exercise Test; Exercise Tolerance; Heart Rate; Heart Transplantation; Humans; Immunosuppressive Agents; Middle Aged; Nitric Oxide; Patient Selection; Placebos; Pulmonary Artery; Quality of Life

2010
Role of PPAR gamma/nitric oxide synthase signaling in the cyclosporine-induced attenuation of endothelium-dependent renovascular vasodilation.
    Journal of cardiovascular pharmacology, 2010, Volume: 56, Issue:2

    Topics: Anilides; Animals; Arginine; Carbachol; Cyclosporine; Endothelium-Dependent Relaxing Factors; Immunosuppressive Agents; In Vitro Techniques; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phenylephrine; Pioglitazone; PPAR gamma; Rats; Rats, Wistar; Signal Transduction; Thiazolidinediones; Vasoconstrictor Agents; Vasodilation

2010
Protective effect of trapidil and l-arginine against renal and hepatic toxicity induced by cyclosporine in rats.
    Renal failure, 2010, Volume: 32, Issue:8

    Topics: Animals; Arginine; Chemical and Drug Induced Liver Injury; Cyclosporine; Immunosuppressive Agents; Kidney Diseases; Male; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar; Trapidil; Vasodilator Agents

2010
Effects of cryogenic sample analysis on molecular depth profiles with TOF-secondary ion mass spectrometry.
    Analytical chemistry, 2010, Oct-01, Volume: 82, Issue:19

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Arginine; Cyclosporine; Deuterium Oxide; Oligopeptides; Spectrometry, Mass, Secondary Ion; Temperature

2010
TGF-β1 gene polymorphism in renal transplant patients with and without gingival overgrowth.
    Oral diseases, 2011, Volume: 17, Issue:4

    Topics: Adenine; Adolescent; Adult; Aged; Arginine; Case-Control Studies; Codon; Cyclosporine; Cytosine; Female; Gene Frequency; Genotype; Gingival Overgrowth; Guanine; Haplotypes; Humans; Immunosuppressive Agents; Kidney Transplantation; Leucine; Male; Middle Aged; Polymorphism, Single Nucleotide; Proline; Promoter Regions, Genetic; Thymine; Transforming Growth Factor beta1; Young Adult

2011
The effect of calcineurin inhibitors on endothelial and platelet function in renal transplant patients.
    Clinical nephrology, 2011, Volume: 76, Issue:3

    Topics: Adult; Arginine; Calcineurin Inhibitors; Cyclosporine; Endothelium, Vascular; Female; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Mycophenolic Acid; Nitric Oxide Synthase; P-Selectin; Platelet Activation; Platelet Aggregation; Tacrolimus

2011
Late effects of renal transplantation on endothelial functions and cardiac morphology.
    Transplantation proceedings, 2011, Volume: 43, Issue:7

    Topics: Adult; Arginine; C-Reactive Protein; Case-Control Studies; Cyclosporine; Endothelium, Vascular; Female; Heart; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged; Tacrolimus; Tunica Intima

2011
Cyclosporine attenuates arginine transport, in human endothelial cells, through modulation of cationic amino acid transporter-1.
    American journal of nephrology, 2013, Volume: 37, Issue:6

    Topics: Arginine; Biological Transport; Cationic Amino Acid Transporter 1; Cyclosporine; Endothelial Cells; Human Umbilical Vein Endothelial Cells; Humans; Immunosuppressive Agents; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; Protein Kinase C-alpha

2013
Severe decrease of cyclosporine levels in a heart transplant recipient receiving the direct thrombin inhibitor argatroban.
    Therapeutic drug monitoring, 2014, Volume: 36, Issue:3

    Topics: Antithrombins; Arginine; Creatinine; Cyclosporine; Cytochrome P-450 CYP3A Inducers; Drug Antagonism; Heart Transplantation; Humans; Immunosuppressive Agents; Middle Aged; Pipecolic Acids; Sulfonamides; Transplant Recipients

2014
Oral delivery of paclitaxel nanocrystal (PNC) with a dual Pgp-CYP3A4 inhibitor: preparation, characterization and antitumor activity.
    International journal of pharmaceutics, 2014, Sep-10, Volume: 472, Issue:1-2

    Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Arginine; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chickens; Clarithromycin; Cyclosporine; Cytochrome P-450 CYP3A Inhibitors; Drug Compounding; Gastrointestinal Tract; Hypromellose Derivatives; Ileum; Melanoma, Experimental; Mice; Nanoparticles; Paclitaxel; Particle Size; Rats, Sprague-Dawley; Skin Neoplasms; Surface Properties; Tumor Burden

2014
Association between endothelial and platelet function markers and adiponectin in renal transplanted recipients on cyclosporine and tacrolimus immunosuppression based therapy.
    Nephrology (Carlton, Vic.), 2015, Volume: 20, Issue:6

    Topics: Adiponectin; Adult; Arginine; Biomarkers; Blood Platelets; Case-Control Studies; Cyclosporine; Drug Therapy, Combination; Endothelial Cells; Female; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged; P-Selectin; Platelet Aggregation; Platelet Function Tests; Risk Factors; Tacrolimus; Treatment Outcome; Up-Regulation; Young Adult

2015
The studies of N-Octyl-N-Arginine-Chitosan coated liposome as an oral delivery system of Cyclosporine A.
    The Journal of pharmacy and pharmacology, 2015, Volume: 67, Issue:10

    Topics: Administration, Oral; Animals; Arginine; Chitosan; Cyclosporine; Drug Carriers; Drug Delivery Systems; Drug Liberation; Emulsions; Gastrointestinal Tract; Immunosuppressive Agents; Liposomes; Male; Particle Size; Rats; Rats, Sprague-Dawley

2015
Nebivolol suppresses asymmetric dimethylarginine and attenuates cyclosporine-induced nephrotoxicity and endothelial dysfunction in rats.
    Pharmacological reports : PR, 2016, Volume: 68, Issue:6

    Topics: Acute Kidney Injury; Adrenergic beta-1 Receptor Agonists; Animals; Arginine; Cyclosporine; Dose-Response Relationship, Drug; Endothelium, Vascular; Immunosuppressive Agents; Male; Nebivolol; Nitric Oxide Synthase Type II; Organ Culture Techniques; Oxidative Stress; Rats; Rats, Wistar

2016
Apoptosis and its modulation in human promyelocytic HL-60 cells treated with DNA topoisomerase I and II inhibitors.
    Experimental cell research, 1993, Volume: 207, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Aminoquinolines; Aphidicolin; Apoptosis; Benzamides; Calcium; Calmodulin; Camptothecin; Cell Cycle; Chromatin; Cyclosporine; DNA; Egtazic Acid; Ethers, Cyclic; Humans; Isoquinolines; Leukemia, Experimental; Leukemia, Promyelocytic, Acute; Microscopy, Electron; Naphthalenes; Okadaic Acid; Phosphoprotein Phosphatases; Piperazines; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerase Inhibitors; Polycyclic Compounds; Protein Kinase C; Spermine; Staurosporine; Teniposide; Tetradecanoylphorbol Acetate; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Zinc

1993
O-demethylation of epipodophyllotoxins is catalyzed by human cytochrome P450 3A4.
    Molecular pharmacology, 1994, Volume: 45, Issue:2

    Topics: Biotransformation; Catalysis; Catechols; Chromatography, High Pressure Liquid; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Erythromycin; Etoposide; Humans; Methylation; Microsomes, Liver; Midazolam; Mixed Function Oxygenases; Teniposide

1994
Differential effectiveness of a range of novel drug-resistance modulators, relative to verapamil, in influencing vinblastine or teniposide cytotoxicity in human lymphoblastoid CCRF-CEM sublines expressing classic or atypical multidrug resistance.
    Cancer chemotherapy and pharmacology, 1994, Volume: 33, Issue:4

    Topics: Cyclosporine; Dihydropyridines; Dose-Response Relationship, Drug; Drug Resistance; Drug Screening Assays, Antitumor; Flunarizine; Humans; Leukemia, T-Cell; Piperidines; Quinidine; Teniposide; Triazines; Tumor Cells, Cultured; Verapamil; Vinblastine

1994
Chemotherapy with focal therapy can cure intraocular retinoblastoma without radiotherapy.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1996, Volume: 114, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; Child, Preschool; Combined Modality Therapy; Cryotherapy; Cyclosporine; Eye Neoplasms; Fundus Oculi; Humans; Immunosuppressive Agents; Infant; Infant, Newborn; Laser Therapy; Pilot Projects; Retinoblastoma; Teniposide; Vincristine; Visual Acuity

1996
Bone marrow transplantation for therapy-related acute myeloid leukemia in congenital retinoblastoma associated with 13q deletion syndrome.
    Annals of hematology, 2004, Volume: 83, Issue:7

    Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Chromosome Deletion; Chromosomes, Human, Pair 13; Cryosurgery; Cryotherapy; Cyclosporine; DNA-Binding Proteins; Enzyme Inhibitors; Eye Neoplasms; Female; Histone-Lysine N-Methyltransferase; Humans; Infant, Newborn; Leukemia, Myeloid; Myeloid-Lymphoid Leukemia Protein; Neoplasm Proteins; Neoplasm Recurrence, Local; Neoplasms, Multiple Primary; Neoplasms, Second Primary; Peripheral Blood Stem Cell Transplantation; Proto-Oncogenes; Remission Induction; Retinoblastoma; Teniposide; Topoisomerase II Inhibitors; Transcription Factors; Vincristine

2004