arginine has been researched along with cyclic gmp in 1085 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 15 (1.38) | 18.7374 |
1990's | 685 (63.13) | 18.2507 |
2000's | 243 (22.40) | 29.6817 |
2010's | 118 (10.88) | 24.3611 |
2020's | 24 (2.21) | 2.80 |
Authors | Studies |
---|---|
Jarrousse, C; Rosselin, G | 1 |
Linebaugh, BE; Mulder, JA; Rillema, JA | 1 |
Inoue, N; Takahashi, K | 1 |
Leysen, JE; Pauwels, PJ | 1 |
Braun, MS; Heckenberger, RE; Klockenbusch, W; Schröder, H; Schrör, K; Strobach, H | 1 |
Boscá, L; Genaro, AM; Hortelano, S | 2 |
Auguet, M; Braquet, P; Chabrier, PE; Delaflotte, S; Goulin-Schulz, J; Lonchampt, MO | 2 |
Joly, GA; Schini, VB; Vanhoutte, PM | 2 |
Siragy, HM | 1 |
Kindybalyuk, AM; Kovalenko, TN; Sagach, VF | 1 |
Godfraind, T; Krippeit-Drews, P; Morel, N | 1 |
Dumont, JE; Esteves, RZ; van Sande, J | 1 |
Altiok, N; Fredholm, BB | 1 |
Aronson, WJ; Bush, PA; Dorey, FJ; Ignarro, LJ; Rajfer, J | 1 |
Kostic, MM; Schrader, J | 1 |
Anggard, E; Mollace, V; Pistelli, A; Salvemini, D; Vane, J | 2 |
Farrar, MA; Shaul, PW; Zellers, TM | 1 |
Carretero, OA; Farhy, RD; Garvin, JL; Scicli, G; Stoos, BA | 1 |
Ramwell, PW; Thomas, G | 2 |
Fleming, I; Gray, GA; Schuller, F; Stoclet, JC | 1 |
Freeman, RH; Johnson, RA | 1 |
Laustiola, KE; Manninen, V; Metsä-Ketelä, T; Pörsti, I; Vapaatalo, H; Vuorinen, P | 1 |
Billiar, TR; Curran, RD; Di Silvio, M; Harbrecht, BG; Murray, SA; Ochoa, JB; Simmons, RL; Stadler, J; Williams, DL | 1 |
Buga, GM; Ignarro, LJ | 1 |
Esumi, H; Hishikawa, K; Kato, R; Nakaki, T; Ohshima, H; Saruta, T; Suzuki, H; Tsuda, M | 1 |
Omar, HA; Wolin, MS | 1 |
Carey, RM; Johns, RA; Peach, MJ; Siragy, HM | 1 |
Boje, KM; Skolnick, P | 1 |
Klockenbusch, W; Schrör, K; Strobach, H | 1 |
Cherry, PD; Gewitz, MH; Mathew, R; Omar, HA; Wolin, MS | 1 |
Fukuda, N; Hatano, M; Izumi, Y; Soma, M; Watanabe, M; Watanabe, Y | 1 |
Goy, MF; McGehee, DS; Oxford, GS | 1 |
Park, J; Rikihisa, Y | 1 |
Lawson, DL; Mehta, JL; Mehta, P; Nichols, WW; Yang, BC | 1 |
Harada, T; Hirayama, T; Kawabe, J; Morita, K; Ogawa, Y; Onodera, S; Takeda, A; Tobise, K | 2 |
Gross, SS; Levi, R; Park, KH; Rubin, LE | 1 |
Eguchi, S; Emori, T; Hirata, Y; Imai, T; Kanno, K; Marumo, F; Ohta, K | 2 |
Van Amsterdam, JG; Wemer, J | 1 |
Cailmail, S; Hadengue, A; Lebrec, D; Moreau, R; Oberti, F; Ohsuga, M; Pussard, E; Sogni, P | 1 |
Coyle, JT; Lyons, WE; Puttfarcken, PS | 1 |
Figueroa, R; Omar, HA; Omar, RA; Wolin, MS | 1 |
Kato, M | 1 |
dos Santos, IR; Duarte, ID; Ferreira, SH; Lorenzetti, BB | 1 |
Reiser, G | 2 |
Campbell, WB; Pfister, SL | 1 |
Raij, L; Shultz, PJ | 1 |
Duarte, ID; Ferreira, SH | 2 |
Becker, RH; Schölkens, BA; Wiemer, G | 1 |
Agulló, L; García, A | 2 |
Bradley, ME; Buxton, IL; Dalziel, HH; Keef, K; Sanders, KM; Ward, SM; Westfall, DP | 1 |
Bucher, B; Ouedraogo, S; Paya, D; Stoclet, JC; Tschöpl, M | 1 |
Corbett, JA; Lancaster, JR; McDaniel, ML; Sweetland, MA; Wang, JL | 2 |
Caramelo, C; Casado, S; Cernadas, MR; Digiuni, E; Espinosa, G; Gallego, MJ; Hernando, L; López-Farré, A; Riesco, A | 1 |
Gray, DW; Marshall, I | 1 |
Barnes, PJ; Crawley, DE; Evans, TW; Liu, SF; Rohde, JA | 1 |
Briggs, CA; Hughes, ML; Murad, F; Sheng, H | 1 |
Förstermann, U; Helgren, MC; Kimber, ND; Klabunde, RE; Kuk, JE | 1 |
Edwards, RM; Nambi, P; Pullen, M | 1 |
el Nahas, AM; Haylor, J; Muchaneta-Kubara, EC; Wight, JP | 1 |
Dong, SY; Su, JY; Tang, CS; Tang, J; Yang, J; Zhang, LY | 1 |
Hisayama, T; Moritoki, H; Takeuchi, S; Yoshikawa, T | 1 |
Conrad, KP; Whittemore, SL | 1 |
Hisayama, T; Kondoh, W; Miyano, H; Moritoki, H; Takeuchi, S | 1 |
Gupta, BB; Heil, K; Spessert, R; Vollrath, L | 1 |
Belushkina, NN; Severina, IS | 1 |
Boekhoff, I; Breer, H; Klemm, T | 1 |
Costa, E; Kiedrowski, L; Wroblewski, JT | 2 |
Ishii, K; Murad, F; Schmidt, HH; Sheng, H; Warner, TD | 1 |
Chapman, PF; Haley, JE; Wilcox, GL | 1 |
Schröder, H; Schrör, K; Strobach, H | 1 |
Schini, VB; Vanhoutte, PM | 1 |
Billiar, TR; Di Silvio, M; Geller, DA; Hoffman, RA; Madariaga, J; Nussler, AK; Selby, R; Simmons, RL | 1 |
Catravas, JD; Marczin, N; Ryan, US | 1 |
Arnal, JF; Michel, JB; Warin, L | 1 |
Chen, X; Gillis, CN | 2 |
Föstermann, U; Mitchell, JA; Murad, F; Nakane, M; Pollock, JS; Schmidt, HH; Sheng, H | 1 |
Corbett, JA; Hughes, JH; Lancaster, JR; McDaniel, ML; Sweetland, MA; Wang, JL; Wolf, BA | 1 |
Nunokawa, Y; Tanaka, S | 1 |
Bockaert, J; Lafon-Cazal, M; Lerner-Natoli, M; Manzoni, O; Rondouin, G | 1 |
Hisayama, T; Kondoh, W; Moritoki, H; Takeuchi, S | 2 |
Lang, D; Lewis, MJ | 1 |
Ishii, K; Murad, F; Sheng, H | 1 |
East, SJ; Garthwaite, J | 2 |
Bredt, DS; Dawson, TM; Dawson, VL; London, ED; Snyder, SH | 1 |
Hisayama, T; Moritoki, H; Takeuchi, S; Ueda, H; Yamamoto, T | 1 |
Busse, R; Lamontagne, D; Pohl, U | 1 |
Bast, A; Brozius, MM; Jansen, W; Leurs, R; Timmerman, H | 1 |
Förstermann, U; Ishii, K; Murad, F; Sheng, H; Warner, TD | 1 |
Cohen, RA; Cowan, CL | 1 |
Okamura, T; Toda, N | 1 |
Biondi, ML; Feletou, M; Peglion, JL; Vanhoutte, PM; Vilaine, JP; Villeneuve, N | 1 |
Brenner, BM; Lamas, S; Marsden, PA; Michel, T | 1 |
Caramelo, C; Casado, S; Gallego, MJ; Grandes, S; Hernando, L; López Farré, A; Millas, I; Riesco, A | 1 |
Cachofeiro, V; Nasjletti, A | 1 |
Chen, PY; Sanders, PW | 2 |
Grinstein, S; Rotstein, OD; Sudsbury, RA; Swallow, CJ | 1 |
Bogle, RG; Coade, SB; Mann, GE; Moncada, S; Pearson, JD | 1 |
Busse, R; Jackson, WF | 1 |
Ahlner, J; Axelsson, KL; Grundström, N; Ljusegren, ME | 1 |
Katusić, ZS | 1 |
Gräser, T; Vanhoutte, PM | 1 |
Durante, W; Junquero, DC; Kroll, MH; Schafer, AI; Schini, VB; Scott-Burden, T; Vanhoutte, PM | 1 |
Bellan, JA; Hood, JS; Kadowitz, PJ; McMahon, TJ | 1 |
Ishii, K; Murad, F; Sheng, H; Warner, TD | 2 |
Johns, RA; Rengasamy, A | 1 |
Buchholz, RA; Dundore, RL; O'Connor, B; Pagani, ED; Pratt, PF | 1 |
Stoclet, JC | 1 |
Duarte, ID; Ferreira, SH; Lorenzetti, BB | 1 |
Buchan, KW; Martin, W | 1 |
Pickard, RS; Powell, PH; Zar, MA | 2 |
Miyachi, E; Miyakawa, A; Murakami, M | 1 |
Komori, S; Ohashi, H; Sugisawa, K; Takewaki, T | 1 |
Beasley, D; Brenner, BM; Schwartz, JH | 1 |
el-Fakahany, EE; Pou, S; Pou, WS; Rosen, GM | 2 |
Fleming, I; Gray, GA; Julou-Schaeffer, G; Parratt, JR; Stoclet, JC | 2 |
Cavanaugh, CT; Laychock, SG; Modica, ME | 1 |
Lang, D; Smith, JA | 1 |
Cler, J; Emmett, MR; Iyengar, S; Mick, S; Rao, TS; Wood, PL | 1 |
Moncada, S; Palmer, RM; Radomski, MW | 1 |
Busse, R; Mülsch, A | 1 |
Okada, D; Shibuki, K | 1 |
Junquero, DC; Schini, VB; Scott-Burden, T; Vanhoutte, PM | 1 |
Mannaioni, PF; Masini, E; Pistelli, A; Salvemini, D; Vane, J | 1 |
Mannaioni, PF; Masini, E; Pistelli, A; Salvemini, D; Vane, JR | 1 |
Allen, SP; Chester, AH; Khagani, A; Luu, TN; Musumeci, F; O'Neil, GS; Ridley, P; Tadjkarimi, S; Yacoub, MH | 1 |
Braquet, P; Chabrier, PE; Demerlé-Pallardy, C; Lonchampt, MO | 1 |
Hecker, M; Vane, JR; Walsh, DT | 1 |
Schott, C; Stoclet, JC; Topouzis, S | 1 |
Anggard, E; Mollace, V; Salvemini, D; Vane, J | 1 |
Boulanger, CM; Lüscher, TF | 1 |
Baron, BM; Cheng, HC; Doherty, NS; Lambert, LE; McDonald, IA; Whitten, JP | 1 |
Förstermann, U; Frölich, JC; Kuhn, M; Otten, A | 1 |
Moncada, S; Palmer, RM; Rees, DD; Schulz, R | 1 |
Bing, RJ; Menon, NK | 1 |
Fineman, JR; Heymann, MA; Soifer, SJ | 1 |
Ito, M; Karachot, L | 1 |
Nakane, M | 1 |
Anggard, E; Mannaioni, PF; Masini, E; Salvemini, D; Vane, J | 1 |
Ishii, K; Kerwin, JF; Murad, F | 1 |
Förstermann, U; Gorsky, L; Heller, M; Ishii, K; Kerwin, JF; Murad, F; Pollock, J | 1 |
Ballermann, BJ; Marsden, PA | 1 |
Durate, ID; Ferreira, SH; Lorenzetti, BB | 1 |
Boulanger, C; Lüscher, TF | 1 |
Förstermann, U; Gorsky, LD; Ishii, K; Murad, F | 1 |
Chang, B; Huang, ZJ; Ishii, K; Kerwin, JF; Murad, F | 1 |
Moncada, S; Palmer, RM; Raij, L; Tolins, JP | 1 |
Bolden, C; Johnson, A; McKinney, M; Richelson, E; Smith, C | 1 |
Byrns, RE; Fukuto, JM; Ignarro, LJ; Wood, KS | 1 |
Byrns, RE; Fukuto, J; Gold, ME; Ignarro, LJ; Wood, KS | 1 |
Buga, GM; Bush, PA; Fukuto, JM; Ignarro, LJ; Rajfer, J; Wood, KS | 1 |
Johns, RA; Linden, J; Peach, MJ; Tichotsky, A | 1 |
Buga, GM; Byrns, RE; Gold, ME; Ignarro, LJ; Wood, KS | 1 |
Barbul, A; Kirk, SJ; Regan, MC | 1 |
Biondi, ML; Dousa, T; Romero, JC; Vanhoutte, P | 1 |
Fasehun, OA; Griffith, OW; Gross, SS; Jaffe, EA; Levi, R; Rubin, LE | 1 |
Boulanger, C; Moncada, S; Schini, VB; Vanhoutte, PM | 1 |
Knowles, RG; Moncada, S; Palacios, M; Palmer, RM | 2 |
Ramwell, PW; Thomas, G; Vargas, R; Wroblewska, B | 1 |
Basford, RE; Billiar, T; Curran, RD; Kaplan, SS; Simmons, RL; Zdziarski, UE | 1 |
Anderton, M; Garthwaite, J; Southam, E | 1 |
Garthwaite, G; Garthwaite, J; Moncada, S; Palmer, RM | 1 |
Schröder, H; Schrör, K | 1 |
Bredt, DS; Snyder, SH | 1 |
Egami, F; Takahashi, K; Uchida, T | 1 |
Caciacli, F; Ciancetta, S; Ciccarelli, R | 1 |
Deguchi, T | 1 |
Richelson, E; Snider, RM | 1 |
DeCampli, WM; Obayashi, DY; Wanna, FS; Young, JN | 1 |
Cai, Z; Hersey, K; Rhodes, PG; Sigrest, T | 1 |
Gulati, A; Sharma, AC; Singh, G | 1 |
Bian, X; Bird, GS; Gilon, P; Obie, JF; Putney, JW | 1 |
Colasanti, M; Lauro, GM; Mollace, V; Nistico, G; Rodino, P; Rotiroti, D | 1 |
DuCailar, G; Mimran, A; Ribstein, J | 1 |
Giles, WR; Han, X; Shimoni, Y | 1 |
Harada, Y; Nagao, T; Ohara, F; Yamazaki, J | 1 |
Brunner, F; Kukovetz, WR; Stessel, H | 1 |
Abebe, W; Hussain, T; Mustafa, SJ; Olanrewaju, H | 1 |
Fujitani, Y; Karaki, H; Okada, T; Ueda, H; Urade, Y | 1 |
Cook, J; Davis, HR; Hoos, L; McLeod, R; Prioli, NA; Pula, K; Watkins, RW | 1 |
Arbabha, B; Bansinath, M; Garg, UC; Turndorf, H | 1 |
Beasley, D; McGuiggin, M | 1 |
Crepel, F; Daniel, H; Hemart, N; Jaillard, D | 1 |
Craven, PA; DeRubertis, FR; Studer, RK | 1 |
Ando, J; Kamiya, A; Korenaga, R; Sakuma, I; Toyo-oka, T; Tsuboi, H; Yang, W | 1 |
Byam-Smith, M; Garfield, RE; Izumi, H; Yallampalli, C | 1 |
Fujisawa, Y; Fujita, N; Hayashi, H; Okamoto, M; Shibanaka, Y; Takai, M; Umemura, I | 1 |
Busse, R; Fleming, I; Hecker, M | 1 |
Anfossi, G; Cavalot, F; Massucco, P; Mattiello, L; Mularoni, E; Trovati, M | 2 |
Bockaert, J; Culcasi, M; Gaven, F; Lafon-Cazal, M; Pietri, S | 1 |
Patel, J; Pullan, LM; Stumpo, RJ; Thompson, C; Zinkand, WC | 1 |
Marumo, F; Nonoguchi, H; Owada, A; Sakamoto, H; Terada, Y; Tomita, K | 1 |
De Kimpe, SJ; Nijkamp, FP; Radomski, MW; van Amsterdam, JG; Van Heuven-Nolsen, D | 1 |
Horning, KM; Shaul, PW; Wells, LB | 1 |
Arnal, JF; Battle, T; Ménard, J; Michel, JB | 2 |
Aleppo, G; Canonico, PL; Scapagnini, U; Sortino, MA | 1 |
Catravas, JD; Cheng, C; Marczin, N; Milici, A; Papapetropoulos, A; Snead, MD | 1 |
Damais, C; Drapier, JC; Dugas, B; Kolb, JP; Paul-Eugene, N; Yamaoka, K | 1 |
Diana, JN; Fiscus, RR; Hao, H; Wang, X | 1 |
Cayatte, AJ; Cohen, RA; Horten, K; Palacino, JJ | 1 |
Dokita, S; Nishimoto, T; Smith, SD; Weiss, RM; Wheeler, MA | 1 |
Nicklas, WJ; Zeevalk, GD | 1 |
Bockaert, J; Culcasi, M; Lafon-Cazal, M; Pietri, S | 1 |
Muallem, S; Star, RA; Tortorici, G; Xu, X | 1 |
Brett, J; Broekman, MJ; Cannon, PJ; Koga, S; Liao, H; Marcus, AJ; Naka, Y; Oz, MC; Pinsky, DJ; Taha, Z | 1 |
Gögelein, H; Popp, R; Schölkens, BA; Wiemer, G | 1 |
Clark, DA; Eloby-Childress, S; Kakkis, JL; Miller, MJ; Munshi, UK; Sadowska-Krowicka, H; Zhang, XJ | 1 |
Depré, C; Hue, L | 1 |
Cohen, RA; Cowan, CL; Najibi, S; Palacino, JJ | 2 |
Cunningham, JM; Delaney, CA; Elphick, MR; Green, IC; Green, MH; Mabley, JG | 1 |
Oyekan, AO | 1 |
Bugnon, O; Schaad, NC; Schorderet, M | 1 |
Enokibori, M; Okamura, T; Toda, N | 2 |
Benjamin, N; Grabowski, PS; Helfrich, M; Ralston, SH; Todd, D | 1 |
Currie, MG; Kasten, TP; Misko, TP; Nickols, GA; Settle, SL | 1 |
Hartell, NA | 1 |
Hisayama, T; Imagawa, M; Kondoh, W; Moritoki, H; Takeuchi, S | 1 |
Andriopoulou, P; Haralabopoulos, G; Maragoudakis, ME; Peristeris, P; Pipili-Synetos, E; Sakkoula, E | 1 |
Levi, R; Park, KH | 1 |
Chalimoniuk, M; Gadamski, R; Samochocki, M; Strosznajder, J | 1 |
Inoue, M; Kida, T; Kobayashi, K; Kuroki, T | 1 |
Cavallo, G; Chessa, MA; Cifone, MG; Cironi, L; Festuccia, C; Pensa, V; Santoni, A; Tubaro, E | 1 |
Iadecola, C; Xu, X; Zhang, F | 1 |
Bing, RJ; Dudek, RR; Giesler, G; Pinto, V; Wildhirt, S | 1 |
Ambs, S; Felley-Bosco, E; Harris, CC; Keefer, LK; Lowenstein, CJ | 1 |
Bredt, DS; Dinger, B; Fidone, SJ; Stensaas, LJ; Wang, ZZ | 1 |
Billiar, TR; Di Silvio, M; Freeswick, PD; Geller, DA; Lancaster, JR; Liu, ZZ; Lowenstein, CL; Nussler, AK; Simmons, RL; Sweetland, MA | 1 |
de Vente, J; Garthwaite, J; Gittins, SR; Morris, R; Southam, E | 1 |
Graier, WF; Holzmann, S; Kukovetz, WR; Paschke, E; Windischhofer, W | 1 |
Grooms, SY; Jones, LS | 1 |
Bailly, C; Imbert-Teboul, M; Néant, F | 1 |
Arock, M; Bécherel, PA; Debré, P; Dugas, B; Guillosson, JJ; Le Goff, L; Mossalayi, MD; Ouaaz, F | 1 |
Coon, SL; Klein, DC; Lin, AM; Schaad, NC; Schulz, PE | 1 |
Armstead, WM; Leffler, CW; Parfenova, H; Shibata, M; Zuckerman, SL | 1 |
Garg, LC; Guzman, NJ; Madsen, KM; Tisher, CC; Tojo, A | 1 |
Ando, M; Kunii, S; Nagata, Y; Tatematsu, T | 1 |
Dunn, MS; Snyder, GD; Van Voorhis, BJ; Weiner, CP | 1 |
Amerini, S; Geppetti, P; Granger, HJ; Ledda, F; Maggi, CA; Masini, E; Morbidelli, L; Ziche, M | 1 |
Ma, L; Morita, I; Murota, S | 1 |
Cummings, JA; Malenka, RC; Nicola, SM | 1 |
McKenna, TM; Tao, S | 1 |
Brown, JF; Korolkiewicz, R; Tepperman, BL; Whittle, BJ | 1 |
Blum, M; Cabili, S; Iaina, A; Maree, A; Peer, G; Schwartz, D; Serban, I; Wollman, Y | 1 |
Arnal, JF; Gonzalez, W; Pueyo, ME; Pussard, E | 1 |
Hiraoka, M; Kigoshi, S; Muramatsu, I; Sudo, M; Tsuchida, S | 1 |
Belova, N; Diaz, MC; Duvilanski, BH; Lasaga, M; McCann, SM; Pisera, D; Rettori, V; Seilicovich, A; Zambruno, C | 1 |
Bohr, D; Cabrera, C | 1 |
Bauer, MB; Gebhart, GF; Murphy, S | 1 |
Glusa, E | 1 |
Armstead, WM | 2 |
Raij, L; Shultz, PJ; Tolins, JP; Westberg, G | 1 |
el-Fakahany, EE; Hu, J; Lee, JH | 1 |
Bassenge, E | 1 |
Finkel, MS; Hattler, BG; Mayer, OH; Oddis, CV; Simmons, RL | 1 |
Brain, SD; Kajekar, R; Moore, PK | 1 |
Chik, CL; Ho, AK; Murdoch, G; Ogiwara, T | 1 |
Acuña, C; Cudeiro, J; Grieve, KL; Martínez-Conde, S; Rivadulla, C; Rodríguez, R | 2 |
Bebout, DE; Chugh, DK; Katayama, M; Lahiri, S; Mokashi, A; Ray, DK | 1 |
Akesson, B; Lundquist, I; Panagiotidis, G; Rydell, EL | 1 |
Chung, JJ; Rockey, DC | 1 |
Bockaert, J; Fagni, L; Lafon-Cazal, M; Lerner-Natoli, M; Manzoni, O; Rondouin, G | 1 |
Klatt, P; List, BM; Mayer, B; Schmidt, K | 1 |
Ikeda, M; Ikeda, U; Kano, S; Ohkawa, F; Shimada, K | 1 |
Curzen, NP; Evans, TW; Griffiths, MJ; Liu, S; Messent, M | 1 |
Armstead, WM; Devine, JO; Rebich, S | 1 |
Bloch, KD; Hochachka, PW; Kawai, N; Staples, JF; Val, VM; Zapol, WM | 1 |
Clementi, E; Nisticò, G; Sciorati, C; Vecchio, I | 1 |
Edvinsson, L; Jansen-Olesen, I; Lassen, NA; Paulson, OB; Wang, Q; You, JP; Zhang, W | 1 |
Grötsch, H; Hropot, M; Klaus, E; Langer, KH; Linz, W; Schölkens, BA; Wiemer, G | 1 |
Hirahashi, J; Hishikawa, K; Kato, R; Marumo, T; Nakaki, T; Saruta, T; Suzuki, H | 1 |
Broner, CW; O'Dorisio, MS; O'Dorisio, TM; Rosenberg, RB | 1 |
Fang, MZ; Garg, LC; Guzman, NJ; Ingelfinger, JR; Tang, SS | 1 |
Bennett, MR; Lin, YQ | 1 |
Bousquet, J; Dugas, B; Paul-Eugène, N; Pène, J | 1 |
Galle, J; Schini, VB; Schollmeyer, P; Stunz, P; Wanner, C | 1 |
Bartoli, F; Billiar, TR; Di Silvio, M; Dorko, K; Freeswick, P; Geller, DA; Liu, ZZ; Nussler, AK | 1 |
Clementi, E; Corasaniti, MT; Nisticò, G; Vecchio, I | 1 |
Deliconstantinos, G; Stavrides, JC; Villiotou, V | 1 |
Chun, SY; Eisenhauer, KM; Hsueh, AJ; Kubo, M | 1 |
Bocian, RC; Chao, AC; Dong, YJ; Gardner, P; Hsu, YP; Kouyama, K; Moss, RB | 1 |
Conrad, KP; Danielson, LA | 1 |
Espinosa, J; Esteva, M; Farber, M; Flawiá, MM; Montagna, AE; Paveto, C; Pereira, C; Torres, HN | 1 |
Dalkara, T; Dawson, TM; Fishman, MC; Huang, PL; Irikura, K; Lee, WS; Ma, J; Moskowitz, MA; Snyder, SH | 1 |
Duffy, C; Hazelwood, R; Salter, M | 1 |
Cahill, PA; Foster, C; Gingalewski, C; Redmond, EM; Sitzmann, JV; Wu, Y | 1 |
Amore, A; Bussolino, F; Cacace, G; Costamagna, C; Ghigo, D; Gianoglio, B; Mazzucco, G; Peruzzi, L; Picciotto, G; Porcellini, MG | 1 |
Akimitsu, T; Gute, DC; Korthuis, RJ | 1 |
Bosia, A; Bussolino, F; Costamagna, C; Deharo, E; Gabrielli, G; Gautret, P; Ghigo, D; Ginsburg, H; Giribaldi, G; Pescarmona, G; Todde, R; Ulliers, D | 1 |
Bischof, G; Bredt, DS; Brenman, J; Machen, TE | 1 |
Depré, C; Goudemant, JF; Hue, L; Mottet, I; Vanoverschelde, JL | 1 |
Hong, CY; Huang, YT; Lai, LJ | 1 |
Belia, S; Chiorean, M; Corinaldesi, R; De Giorgio, R; Distrutti, E; Fano, G; Fiorucci, S; Morelli, A; Santucci, L; Stanghellini, V | 1 |
Ginès, P; Martin, PY; McMurtry, I; Morris, K; Niederberger, M; Schrier, RW; Tsai, P; Xu, DL | 1 |
Adams, MR; Celermajer, DS; Forsyth, CJ; Jessup, W; Robinson, J | 1 |
Coffey, RG; Fitzpatrick, DF; Hirschfield, SL; Jantzen, P; Ricci, T | 1 |
Gong, CN; Han, QD; Tang, J; Tian, Q; Zhang, ZK; Zhao, D; Zhao, YT | 1 |
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Barrientos-Moreno, L; Espinosa-Urgel, M; Molina-Henares, MA; Ramos-González, MI | 2 |
Abbaszadeh, F; Ahmadpour, Y; Fakhri, S; Ghanbarveisi, F; Gravandi, MM; Iranpanah, A; Kooshki, L; Moradi, SZ; Rezaei, H | 1 |
Aman, W; Dehpour, AR; Haider, A; Khan, MI; Khan, SN; Mumtaz, F; Naveed, A; Nikoui, V; Ullah, N; Wahab, A; Zaman, H | 1 |
Ahmadimoghaddam, D; Izadidastenaei, Z; Mohammadi, S; Salehi, I; Zarei, M | 1 |
Beghetti, M; Milano, G; Reinero, M; Samaja, M; Segesser, LKV; Tozzi, P | 1 |
Abbaszadeh, F; Fakhri, S; Farzaei, MH; Moradi, N | 1 |
Abbaszadeh, F; Fakhri, S; Farzaei, MH; Mohammadi, S; Mohammadi-Farani, A | 1 |
Haney, CH; Hossain, SS; Liu, Z; Morales Moreira, Z | 1 |
Maratha, S; Sharma, V; Walia, V | 2 |
Chen, Y; Liu, Z; Xu, C; Yan, R; Yang, H; Zhang, Z; Zhu, D | 1 |
He, ZG; Hu, L; Zhang, H; Zhang, J | 1 |
da Motta, KP; Luchese, C; Martins, CC; Reis, AS; Wilhelm, EA | 1 |
Harada, K; Ishida, R; Kitaguchi, T; Mita, M; Osuga, Y; Takizawa, M; Tsuboi, T; Ueda, H | 1 |
Bielecka-Papierz, G; Kołtun-Jasion, M; Poleszak, E; Radziwoń-Zaleska, M; Serefko, A; Szewczyk, B; Szopa, A; Talarek, S; Wróbel, A | 1 |
Afolabi, OA; Ajayi, AF; Akhigbe, RE | 1 |
Castro Perez, A; Gama Duarte, ID; Lima Romero, TR; Teixeira, LRM | 1 |
Khodayar, MJ; Mohtadi, S; Rahemi, M; Rajabi Vardanjani, H | 1 |
Bederska-Łojewska, D; Bielecka-Papierz, G; Jakóbczuk, M; Listos, J; Orzelska-Górka, J; Poleszak, E; Serefko, A; Szewczyk, B; Szopa, A; Szponar, J; Talarek, S; Turek, J | 1 |
Angeli, S; Cutruzzolà, F; Espinosa-Urgel, M; Molina-Henares, MA; Paiardini, A; Rinaldo, S; Scribani-Rossi, C | 1 |
23 review(s) available for arginine and cyclic gmp
Article | Year |
---|---|
The L-arginine-NO pathway and cyclic GMP in the vessel wall.
Topics: Animals; Arginine; Culture Techniques; Cyclic GMP; Muscle, Smooth, Vascular; Nitric Oxide; Rats; Vasodilation | 1991 |
Ribonuclease T1, Structure and function.
Topics: Amino Acid Sequence; Amino Acids; Animals; Arginine; Aspergillus; Binding Sites; Chromatography, Gel; Copper; Cyclic GMP; Disulfides; Endonucleases; Histidine; Hydrogen-Ion Concentration; Immune Sera; Iodoacetates; Kinetics; Optical Rotatory Dispersion; Precipitin Tests; Protein Binding; Protein Conformation; Rabbits; Ribonucleases; Tryptophan; Zinc | 1970 |
[Cyclic GMP: its biosynthesis and physiological role].
Topics: Animals; Arginine; Brain; Cattle; Cell Movement; Cyclic GMP; Enzyme Activation; Fatty Acids, Unsaturated; Guanylate Cyclase; Humans; Mice; Muscle Contraction; Myocardial Contraction; Nitroso Compounds; Photoreceptor Cells; Rabbits; Rats | 1984 |
Effects of cytokines and nitric oxide donors on insulin secretion, cyclic GMP and DNA damage: relation to nitric oxide production.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Line; Cells, Cultured; Cyclic GMP; Cytokines; DNA; DNA Damage; Free Radicals; Insulin; Insulin Secretion; Interleukin-1; Islets of Langerhans; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Vasodilator Agents | 1994 |
Coronary vasomotor responses: role of endothelium and nitrovasodilators.
Topics: Amino Acid Oxidoreductases; Arginine; Biotransformation; Blood Platelets; Cell Adhesion; Cyclic GMP; Endothelium, Vascular; Humans; In Vitro Techniques; Isoenzymes; Myocardial Ischemia; Nitric Oxide; Nitric Oxide Synthase; Oxygen Consumption; Platelet Activation; Vasoconstriction; Vasodilator Agents | 1994 |
Inflammatory pain: the role of cytokines and its control by drugs which release nitric oxide.
Topics: Analgesics; Arginine; Cyclic GMP; Cyclooxygenase Inhibitors; Cytokines; Down-Regulation; Humans; Hyperalgesia; Inflammation; Nitric Oxide; Nociceptors; Sympatholytics | 1993 |
Release of nitric oxide from astroglial cells: a key mechanism in neuroimmune disorders.
Topics: Animals; Arginine; Citrulline; Cyclic GMP; Invertebrates; NADP; Nerve Tissue Proteins; Nervous System; Neuronal Plasticity; Nitric Oxide; Nitric Oxide Synthase; Signal Transduction; Smell; Species Specificity | 1995 |
Prevention of preeclampsia with calcium supplementation and its relation with the L-arginine:nitric oxide pathway.
Topics: Arginine; Calcium; Cyclic GMP; Female; Food, Fortified; Hemodynamics; Homeostasis; Humans; Hypertension; Nitric Oxide; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular | 1996 |
[Septic shock and nitric oxide].
Topics: Arginine; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Humans; Hypotension; Leukocytes; Nitric Oxide; Nitric Oxide Synthase; Phagocytes; Randomized Controlled Trials as Topic; Shock, Septic | 1997 |
[Nitric oxide (NO), vascular protection factor. Biology, physiological role and biochemistry of NO].
Topics: Animals; Arginine; Calcium; Cyclic GMP; Endothelium, Vascular; Guanylate Cyclase; Humans; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Vasoconstriction; Vasodilation | 1998 |
S-nitrosylation of proteins.
Topics: Animals; Apoptosis; Arginine; Cyclic GMP; Cysteine; Hemoglobins; HIV Protease; Humans; Immune System; Ion Transport; Macrophages; Nitric Oxide; Nitroso Compounds; Oxidation-Reduction; Platelet Aggregation; Protein Processing, Post-Translational; Signal Transduction | 1999 |
Effects of nitric oxide on the contraction of skeletal muscle.
Topics: Animals; Arginine; Cyclic GMP; Depression, Chemical; Dogs; Electric Stimulation; Energy Metabolism; Glucose Transporter Type 4; Humans; Isometric Contraction; Mice; Monosaccharide Transport Proteins; Muscle Contraction; Muscle Proteins; Muscle, Skeletal; Myocardial Contraction; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Oxygen Consumption; Protein Processing, Post-Translational; Rabbits; Rats; Reactive Oxygen Species; Stress, Mechanical; Swine; Tetany; Vasodilation | 1999 |
The role of nitric oxide synthase/nitric oxide in vascular smooth muscle control.
Topics: Administration, Inhalation; Amyl Nitrite; Arginine; Calcium Signaling; Cardiopulmonary Bypass; Cyclic GMP; Endothelium, Vascular; Humans; Infusions, Intravenous; Intraoperative Care; Isoenzymes; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitroglycerin; Nitroprusside; Vascular Resistance | 2000 |
The nitric oxide pathway in the cardiovascular system.
Topics: Animals; Arginine; Cardiovascular System; Cyclic GMP; Guanylate Cyclase; Humans; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Peroxynitrous Acid | 2002 |
Potential mechanisms of impaired endothelial function in arterial hypertension and hypercholesterolemia.
Topics: Animals; Arginine; Biological Availability; Cyclic GMP; Endothelium, Vascular; Humans; Hypercholesterolemia; Hypertension; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Prognosis; Vasodilation | 2003 |
[Discovery and significance of NO].
Topics: Animals; Arginine; Cyclic GMP; Endothelial Cells; Endothelium-Dependent Relaxing Factors; Free Radicals; Guanylate Cyclase; History, 20th Century; Humans; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase | 2004 |
[Mechanisms of nitric oxide production].
Topics: Arginine; Biopterins; Calcium; Calmodulin; Cyclic GMP; Guanylate Cyclase; Humans; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Phosphorylation; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Transcription, Genetic | 2004 |
Nitric oxide, a biological double-faced janus--is this good or bad?
Topics: Animals; Arginine; Cardiovascular Physiological Phenomena; Cyclic GMP; Endocrine System; Female; Humans; Immune System; Isoenzymes; Male; Nervous System Physiological Phenomena; Nitric Oxide; Nitric Oxide Synthase; Reproduction; Urogenital System | 2006 |
The involvement of the nitric oxide in the effects and expression of opioid receptors during peripheral inflammation.
Topics: Analgesics, Opioid; Anti-Inflammatory Agents; Arginine; Cyclic GMP; Enzyme Inhibitors; Gene Expression Regulation; Guanylate Cyclase; Humans; Inflammation; Intestinal Mucosa; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nociceptin Receptor; Receptors, Opioid | 2007 |
[Role of nitric oxide in the control of the pulmonary circulation: physiological, pathophysiological, and therapeutic implications].
Topics: Animals; Arginine; Clinical Trials as Topic; Cyclic GMP; Humans; Hypertension, Pulmonary; Mice; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Pulmonary Circulation | 2008 |
Nitric oxide pathway in hypertrophied heart: new therapeutic uses of nitric oxide donors.
Topics: Arginine; Biopterins; Cardiomegaly; Cyclic GMP; Humans; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase | 2010 |
Vascular nitric oxide: Beyond eNOS.
Topics: Animals; Arginine; Cardiovascular Diseases; Cell Physiological Phenomena; Cyclic GMP; Endothelium, Vascular; Guanylate Cyclase; Humans; Muscle Contraction; Muscle Tonus; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; S-Nitrosothiols; Signal Transduction | 2015 |
Beyond nitrogen metabolism: nitric oxide, cyclic-di-GMP and bacterial biofilms.
Topics: Animals; Arginine; Bacteria; Biofilms; Cyclic GMP; Energy Metabolism; Environmental Microbiology; Humans; Nitric Oxide; Nitrogen; Signal Transduction | 2018 |
34 trial(s) available for arginine and cyclic gmp
Article | Year |
---|---|
[Vasodilator effect of nitric oxide is a necessary counter-regulation in the spontaneously hypertensive rat].
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Body Weight; Cyclic GMP; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasodilation | 1993 |
Oral L-arginine inhibits platelet aggregation but does not enhance endothelium-dependent dilation in healthy young men.
Topics: Administration, Oral; Adult; Arginine; Blood Platelets; Cross-Over Studies; Cyclic GMP; Double-Blind Method; Endothelium, Vascular; Hemodynamics; Humans; Male; Nitric Oxide; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Vasodilation | 1995 |
Intravenous administration of L-arginine inhibits angiotensin-converting enzyme in humans.
Topics: Adult; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Arginine; Blood Pressure; Cyclic GMP; Glomerular Filtration Rate; Heart Rate; Humans; Infusions, Intravenous; Insulin; Male; Peptidyl-Dipeptidase A; Reference Values; Renal Circulation; Renin; Time Factors; Vascular Resistance | 1995 |
Effects of L-arginine infusion on renal hemodynamics in patients with mild essential hypertension.
Topics: Adult; Arginine; Blood Pressure; Cyclic GMP; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Infusions, Intravenous; Male; Middle Aged; Reference Values; Renal Circulation | 1995 |
Amino acid-induced hyperfiltration--mediators and effect of captopril.
Topics: Arginine; Captopril; Cyclic GMP; Dinoprostone; Female; Glomerular Filtration Rate; Glomerulonephritis, IGA; Glucagon; Humans; Male; Middle Aged; Renal Plasma Flow, Effective; Renin-Angiotensin System; Vascular Resistance | 1994 |
L-arginine infusion decreases peripheral arterial resistance and inhibits platelet aggregation in healthy subjects.
Topics: Adult; Arginine; Cyclic GMP; Double-Blind Method; Gas Chromatography-Mass Spectrometry; Heart Rate; Humans; Male; Nitrates; Nitrites; Platelet Aggregation; Platelet Aggregation Inhibitors; Vascular Resistance | 1994 |
Lack of beneficial effects of L-arginine infusion in primary pulmonary hypertension.
Topics: Adolescent; Adult; Arginine; Cardiac Catheterization; Cardiac Output; Cyclic GMP; Female; Humans; Hypertension, Pulmonary; Infusions, Intravenous; Male; Middle Aged; Oxygen; Pulmonary Wedge Pressure; Vascular Resistance | 1994 |
Differential systemic and pulmonary hemodynamic effects of L-arginine in patients with coronary artery disease or primary pulmonary hypertension.
Topics: Adult; Arginine; Blood Pressure; Coronary Disease; Cyclic GMP; Female; Humans; Hypertension, Pulmonary; Infusions, Intravenous; Male; Middle Aged; Pilot Projects; Signal Transduction; Vascular Resistance | 1996 |
Haemodynamic and biochemical responses to L-arginine and L-lysine infusions in normal subjects: L-arginine-induced vasodilatation cannot be explained by non-specific effects of cationic amino acids.
Topics: Adult; Arginine; Atrial Natriuretic Factor; Blood Pressure; Citrulline; Cyclic GMP; Electrolytes; Extracellular Space; Female; Heart Rate; Humans; Lysine; Male; Nitric Oxide; Vascular Resistance; Vasodilation | 1997 |
Dose-related effect of intravenous L-arginine on muscular blood flow of the calf in patients with peripheral vascular disease: a H215O positron emission tomography study.
Topics: Aged; Arginine; Blood Pressure; Cyclic GMP; Dose-Response Relationship, Drug; Female; Humans; Infusions, Intravenous; Leg; Male; Middle Aged; Muscle, Skeletal; Peripheral Vascular Diseases; Regional Blood Flow; Tomography, Emission-Computed | 1997 |
Differential inhibition of human platelet aggregation and thromboxane A2 formation by L-arginine in vivo and in vitro.
Topics: Adult; Antithrombins; Arginine; Blood Platelets; Cyclic GMP; Enzyme Inhibitors; Humans; In Vitro Techniques; Infusions, Intravenous; Male; Molsidomine; Nitric Oxide Synthase; Platelet Aggregation; Platelet Aggregation Inhibitors; Thromboxane A2; Thromboxane B2; Thromboxanes | 1998 |
Restoring vascular nitric oxide formation by L-arginine improves the symptoms of intermittent claudication in patients with peripheral arterial occlusive disease.
Topics: Aged; Aged, 80 and over; Alprostadil; Arginine; Arterial Occlusive Diseases; Blood Flow Velocity; Chronic Disease; Cyclic GMP; Double-Blind Method; Exercise Test; Female; Femoral Artery; Follow-Up Studies; Humans; Infusions, Intravenous; Intermittent Claudication; Leg; Male; Middle Aged; Nitrates; Nitric Oxide; Peripheral Vascular Diseases; Treatment Outcome; Ultrasonography, Doppler, Duplex; Vasodilation; Vasodilator Agents | 1998 |
L-arginine-induced vasodilation in healthy humans: pharmacokinetic-pharmacodynamic relationship.
Topics: Administration, Oral; Adult; Arginine; Blood Pressure; Cardiac Output; Cyclic GMP; Double-Blind Method; Heart Rate; Humans; Injections, Intravenous; Male; Nitrates; Nitric Oxide; Vasodilation | 1998 |
Indices of activity of the nitric oxide system in hemodialysis patients.
Topics: Arginine; Blood Pressure; Citrulline; Cyclic GMP; Diet; Female; Humans; Male; Middle Aged; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Renal Dialysis; Second Messenger Systems | 1999 |
Randomized, double-blind, placebo-controlled study of arginine supplementation in chronic renal failure.
Topics: Adolescent; Adult; Amino Acids; Arginine; Cyclic GMP; Double-Blind Method; Female; Glomerular Filtration Rate; Humans; Kidney Failure, Chronic; Male; Middle Aged; Nitrates; Nitric Oxide; Placebos; Proteinuria; Renal Circulation | 1999 |
Renal and metabolic effects of L-arginine infusion in kidney transplant recipients.
Topics: Adolescent; Adult; Arginine; Child; Cyclic GMP; Cyclosporine; Female; Glomerular Filtration Rate; Graft Rejection; Hemodynamics; Humans; Immunosuppressive Agents; Infusions, Intravenous; Kidney Transplantation; Male; p-Aminohippuric Acid; Reference Values; Sodium; Vascular Resistance | 1999 |
Early alteration in glomerular reserve in humans at genetic risk of essential hypertension: mechanisms and consequences.
Topics: Adult; Amino Acids; Arginine; Cyclic GMP; Female; Genetic Markers; Glomerular Filtration Rate; Humans; Hypertension; Infusions, Intravenous; Insulin; Insulin Resistance; Kidney Glomerulus; Kidney Tubules, Proximal; Lithium Carbonate; Male; Middle Aged; Nitrates; Nitrites; Phenotype; Risk Factors; Second Messenger Systems | 2001 |
Long-term oral L-arginine administration improves peripheral and hepatic insulin sensitivity in type 2 diabetic patients.
Topics: Administration, Oral; Arginine; Blood Glucose; Blood Pressure; Body Weight; Cyclic GMP; Diabetes Mellitus, Type 2; Diet, Diabetic; Double-Blind Method; Forearm; Glucose Clamp Technique; Glycated Hemoglobin; Heart Rate; Humans; Insulin; Insulin Secretion; Liver; Middle Aged; Potassium; Reference Values; Regional Blood Flow | 2001 |
Paradoxical decrease in plasma NOx by L-arginine load in diabetic and non-diabetic subjects.
Topics: Arginine; Blood Glucose; Blood Pressure; Cyclic GMP; Diabetes Mellitus, Type 2; Endothelium, Vascular; Female; Humans; Hypertension; Male; Middle Aged; Nitrates; Nitric Oxide; Nitrites | 2002 |
Hypercholesterolaemia and treatment with statins do not alter L-arginine-induced changes of renal haemodynamics.
Topics: Aged; Arginine; Blood Pressure; Cohort Studies; Cyclic GMP; Double-Blind Method; Fatty Acids, Monounsaturated; Female; Fluvastatin; Heart Rate; Hemodynamics; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Male; Middle Aged; Natriuresis; Osmolar Concentration; Renal Circulation; Vasodilation; Vasodilator Agents | 2002 |
Acute intravenous L-arginine infusion decreases endothelin-1 levels and improves endothelial function in patients with angina pectoris and normal coronary arteriograms: correlation with asymmetric dimethylarginine levels.
Topics: Angina Pectoris; Arginine; Blood Pressure; Coronary Angiography; Cyclic GMP; Endothelin-1; Endothelium, Vascular; Female; Forearm; Humans; Infusions, Intravenous; Insulin; Male; Middle Aged; Nitric Oxide; Regional Blood Flow; Syndrome | 2003 |
Cardiovascular effects of systemic nitric oxide synthase inhibition with asymmetrical dimethylarginine in humans.
Topics: Arginine; Cardiac Output; Cross-Over Studies; Cyclic GMP; Dose-Response Relationship, Drug; Double-Blind Method; Enzyme Inhibitors; Hemodynamics; Humans; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Vascular Resistance | 2004 |
Subpressor dose asymmetric dimethylarginine modulates renal function in humans through nitric oxide synthase inhibition.
Topics: Adult; Arginine; Cyclic GMP; Humans; Kidney; Male; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; p-Aminohippuric Acid; Renal Circulation; Renin; Sodium | 2004 |
L-arginine improves the symptoms of strokelike episodes in MELAS.
Topics: Administration, Oral; Adolescent; Adult; Amino Acids; Arginine; Cerebral Arteries; Child; Child, Preschool; Cholesterol; Cyclic GMP; Female; Headache; Humans; Male; MELAS Syndrome; Nitric Oxide; Paresis; Seizures; Stroke; Treatment Outcome; Vasodilation; Vision Disorders; Vomiting | 2005 |
Inhibitory effects of endogenous L-arginine analogues on nitric oxide synthesis in platelets: role in platelet hyperaggregability in hypertension.
Topics: Arginine; Blood Platelets; C-Reactive Protein; Cyclic GMP; Female; Fibrinogen; Humans; Hypertension; Interleukin-6; Leucine; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Platelet Aggregation; Tumor Necrosis Factor-alpha | 2007 |
[Sperm parameters in male idiopathic infertility after treatment with prelox].
Topics: Adult; Arginine; Cyclic GMP; Double-Blind Method; Drug Combinations; Flavonoids; Humans; Infertility, Male; Male; Middle Aged; Nitric Oxide Synthase Type III; Plant Extracts; Sperm Capacitation; Spermatozoa; Treatment Outcome | 2007 |
Enhanced concentrations of relevant markers of nitric oxide formation after exercise training in patients with metabolic syndrome.
Topics: Adult; Arginine; Biomarkers; Cyclic GMP; Exercise Therapy; Humans; Lipid Peroxides; Metabolic Syndrome; Middle Aged; Nitric Oxide; Nitrites; Oxidative Stress; Thiobarbituric Acid Reactive Substances | 2008 |
No arguments for increased endothelial nitric oxide synthase activity in migraine based on peripheral biomarkers.
Topics: Area Under Curve; Arginine; Biomarkers; Citrulline; Cyclic GMP; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites | 2010 |
Ramipril sensitizes platelets to nitric oxide: implications for therapy in high-risk patients.
Topics: Adenosine Diphosphate; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Arginine; Biomarkers; Blood Platelets; Cohort Studies; Cyclic GMP; Double-Blind Method; Drug Administration Schedule; Female; Guanylate Cyclase; Humans; Male; Malondialdehyde; Middle Aged; Nitric Oxide; Nitroprusside; Oxidative Stress; Platelet Aggregation; Ramipril; Thrombospondin 1 | 2012 |
L-arginine enriched biscuits improve endothelial function and glucose metabolism: a pilot study in healthy subjects and a cross-over study in subjects with impaired glucose tolerance and metabolic syndrome.
Topics: Arginine; Body Composition; Body Weight; Cholesterol; Cross-Over Studies; Cyclic GMP; Double-Blind Method; Endothelium, Vascular; Female; Glucose Intolerance; Humans; Insulin; Insulin Secretion; Male; Metabolic Syndrome; Middle Aged; Nitric Oxide Synthase Type II; Obesity; Pilot Projects; Snacks; Triglycerides | 2013 |
L-arginine does not improve biochemical and hormonal response in trained runners after 4 weeks of supplementation.
Topics: Adult; Ammonia; Arginine; Cyclic GMP; Dietary Supplements; Double-Blind Method; Exercise; Female; Hormones; Human Growth Hormone; Humans; Hydrocortisone; Insulin; Insulin-Like Growth Factor I; Lactic Acid; Male; Nitrates; Nitric Oxide; Nitrites; Placebos; Running | 2014 |
Combined L-citrulline and glutathione supplementation increases the concentration of markers indicative of nitric oxide synthesis.
Topics: Adolescent; Adult; Animals; Arginine; Biomarkers; Body Mass Index; Citrulline; Cyclic GMP; Dietary Supplements; Double-Blind Method; Glutathione; Healthy Volunteers; Human Umbilical Vein Endothelial Cells; Humans; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Resistance Training; Young Adult | 2015 |
Microvascular effects of the inhibition of dipeptidylpeptidase IV by linagliptin in nondiabetic hypertensive patients.
Topics: Aged; Arginine; Arterial Pressure; C-Reactive Protein; Cyclic GMP; Cystatin C; Dipeptidyl-Peptidase IV Inhibitors; Double-Blind Method; Female; Glycated Hemoglobin; Humans; Hypertension; Linagliptin; Male; Microvessels; Middle Aged; Regional Blood Flow; Retinal Vessels; Transforming Growth Factor beta1 | 2016 |
Combined effects of aerobic exercise and l-arginine ingestion on blood pressure in normotensive postmenopausal women: A crossover study.
Topics: Arginine; Blood Glucose; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cholesterol; Cross-Over Studies; Cyclic GMP; Double-Blind Method; Exercise; Female; Humans; Inflammation Mediators; Middle Aged; Nitric Oxide; Postmenopause; Triglycerides | 2016 |
1028 other study(ies) available for arginine and cyclic gmp
Article | Year |
---|---|
Regulation by glucose and cyclic nucleotides of the glucagon and insulin release induced by amino acids.
Topics: Acetylcholine; Alanine; Amino Acids; Animals; Arginine; Bucladesine; Cyclic GMP; Drug Synergism; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Lysine; Rats; Sodium Chloride; Stimulation, Chemical; Theophylline | 1975 |
Regulation of casein synthesis by polyamines in mammary gland explants of mice.
Topics: Animals; Arginine; Caseins; Cyclic AMP; Cyclic GMP; Female; Hydrocortisone; In Vitro Techniques; Insulin; Mammary Glands, Animal; Mice; Mitoguazone; Ornithine; Ornithine Decarboxylase; Phospholipases; Polyamines; Prolactin; Prostaglandins F; Protein Biosynthesis; Putrescine; Spermidine; Spermine; Transcription, Genetic | 1977 |
The structure and function of ribonuclease T1. XXII. Tryptic cleavages of the single lysyl and arginyl bonds in ribonuclease T1.
Topics: Amino Acids; Arginine; Chemical Phenomena; Chemistry; Cyclic GMP; Guanosine; Lysine; Peptide Fragments; Ribonuclease T1; Ribonucleases; Temperature; Trinitrobenzenes; Trypsin | 1977 |
Blockade of nitric oxide formation does not prevent glutamate-induced neurotoxicity in neuronal cultures from rat hippocampus.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Culture Media, Serum-Free; Cyclic GMP; Depression, Chemical; Dizocilpine Maleate; Glutamates; Glutamic Acid; Hemoglobins; Hippocampus; L-Lactate Dehydrogenase; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rats; Receptors, N-Methyl-D-Aspartate | 1992 |
Prostacyclin rather than nitric oxide lowers human umbilical artery tone in vitro.
Topics: Arginine; Bradykinin; Cyclic GMP; Epoprostenol; Female; Histamine; Humans; Iloprost; In Vitro Techniques; Indomethacin; Molsidomine; Muscle Contraction; Nitric Oxide; Nitroarginine; Serotonin; Umbilical Arteries; Vasodilation | 1992 |
Phorbol esters induce nitric oxide synthase activity in rat hepatocytes. Antagonism with the induction elicited by lipopolysaccharide.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Calcimycin; Carcinogens; Cells, Cultured; Cyclic GMP; Diglycerides; Enzyme Induction; Kinetics; Lipopolysaccharides; Liver; Nitric Oxide Synthase; Phorbol 12,13-Dibutyrate; Phorbol Esters; Rats; Tetradecanoylphorbol Acetate | 1992 |
Lipoteichoic acid: a new inducer of nitric oxide synthase.
Topics: Amino Acid Oxidoreductases; Animals; Aorta; Arginine; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Enzyme Induction; Lipopolysaccharides; Methylene Blue; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Teichoic Acids; Vasoconstriction | 1992 |
Balloon injury induces nitric oxide synthase activity in rat carotid arteries.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Carotid Arteries; Catheterization; Cyclic GMP; Endothelium, Vascular; Enzyme Induction; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitroarginine; Phenylephrine; Rats; Rats, Wistar; Superoxide Dismutase | 1992 |
Endothelium-derived relaxing factor modulates renal interstitial cyclic GMP.
Topics: Animals; Arginine; Cyclic GMP; Dogs; Extracellular Space; Female; Kidney; Nitric Oxide; omega-N-Methylarginine; Renal Dialysis | 1992 |
Functional hyperemia of skeletal muscle: role of endothelium.
Topics: Animals; Arginine; Child; Cyclic GMP; Dogs; Electric Stimulation; Endothelium, Vascular; Gossypol; Humans; Indomethacin; Isometric Contraction; Methylene Blue; Muscles; Nitric Oxide; Regional Blood Flow | 1992 |
Effect of nitric oxide on membrane potential and contraction of rat aorta.
Topics: Amino Acid Oxidoreductases; Animals; Aorta, Thoracic; Arginine; Calcium; Cyclic GMP; Endothelium, Vascular; In Vitro Techniques; Male; Membrane Potentials; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Potassium Chloride; Rats; Rats, Wistar | 1992 |
Nitric oxide as a signal in thyroid.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Calcimycin; Calcium; Carbachol; Cyclic GMP; Dogs; Enzyme Activation; Guanylate Cyclase; Methylene Blue; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Receptors, Muscarinic; Signal Transduction; Thyroid Gland | 1992 |
Bradykinin inhibition of cyclic AMP accumulation in D384 astrocytoma cells. Evidence against a role of cyclic GMP.
Topics: 1-Methyl-3-isobutylxanthine; Arginine; Astrocytoma; Bradykinin; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Humans; Hydroxylamine; Hydroxylamines; Kinetics; NG-Nitroarginine Methyl Ester; Nitroprusside; Pyrrolidinones; Rolipram; Tumor Cells, Cultured | 1992 |
Nitric oxide as a mediator of relaxation of the corpus cavernosum in response to nonadrenergic, noncholinergic neurotransmission.
Topics: Adult; Aged; Arginine; Cyclic GMP; Electric Stimulation; Erectile Dysfunction; Humans; Male; Methylene Blue; Middle Aged; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitroarginine; Organ Culture Techniques; Penile Erection; Penis; Purinones; Synaptic Transmission | 1992 |
Role of nitric oxide in reactive hyperemia of the guinea pig heart.
Topics: Adenosine; Animals; Arginine; Coronary Circulation; Coronary Disease; Cyclic GMP; Hyperemia; In Vitro Techniques; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rabbits; Spectrophotometry | 1992 |
Metabolism of glyceryl trinitrate to nitric oxide by endothelial cells and smooth muscle cells and its induction by Escherichia coli lipopolysaccharide.
Topics: Animals; Arginine; Blood Pressure; Cattle; Cells, Cultured; Cyclic GMP; Cycloheximide; Endothelium, Vascular; Escherichia coli; Hemodynamics; Humans; In Vitro Techniques; Lipopolysaccharides; Muscle, Smooth, Vascular; Nitric Oxide; Nitrites; Nitroglycerin; omega-N-Methylarginine; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats | 1992 |
Oxygen modulates endothelium-derived relaxing factor production in fetal pulmonary arteries.
Topics: Acetylcholine; Animals; Arginine; Cyclic GMP; Endothelium, Vascular; Fetus; Nitric Oxide; Nitroarginine; Oxygen; Pulmonary Artery; Sheep; Vasodilation | 1992 |
Endothelium-derived relaxing factor inhibits transport and increases cGMP content in cultured mouse cortical collecting duct cells.
Topics: Acetylcholine; Animals; Arginine; Biological Transport; Bradykinin; Cattle; Cells, Cultured; Cyclic GMP; Kidney Cortex; Kidney Tubules, Collecting; Mice; Nitric Oxide; Nitroarginine | 1992 |
Identification of guanidino succinate as a putative endogenous source of the endothelium derived relaxing factor.
Topics: Animals; Aorta; Arginine; Cyclic GMP; Endothelium, Vascular; Glycine; Guanidines; Muscle Relaxation; Nitric Oxide; Propionates; Rats; Succinates | 1992 |
Effect of endotoxin on circulating cyclic GMP in the rat.
Topics: Animals; Arginine; Atrial Natriuretic Factor; Cyclic GMP; Endotoxins; Escherichia coli; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Inbred Strains; Thoracic Arteries | 1992 |
Pressure natriuresis in rats during blockade of the L-arginine/nitric oxide pathway.
Topics: Animals; Arginine; Blood Pressure; Cyclic GMP; Heart Rate; Male; Natriuresis; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Renin; Sodium | 1992 |
Endothelium-dependent and -independent effects of exogenous ATP, adenosine, GTP and guanosine on vascular tone and cyclic nucleotide accumulation of rat mesenteric artery.
Topics: Acetylcholine; Adenosine; Adenosine Triphosphate; Animals; Arginine; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Guanosine; Guanosine Triphosphate; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Relaxation; Muscle Tonus; Muscle, Smooth, Vascular; Nitroarginine; Nucleotides; Rats; Rats, Inbred Strains | 1992 |
Association between synthesis and release of cGMP and nitric oxide biosynthesis by hepatocytes.
Topics: Animals; Arginine; Atrial Natriuretic Factor; Corynebacterium Infections; Cyclic GMP; Cytokines; Lipopolysaccharides; Liver; Nitric Oxide; Nitrous Oxide; omega-N-Methylarginine; Propionibacterium acnes | 1992 |
Electrical field stimulation causes endothelium-dependent and nitric oxide-mediated relaxation of pulmonary artery.
Topics: Animals; Arginine; Calcium; Cattle; Cyclic GMP; Electric Stimulation; Endothelium, Vascular; Extracellular Space; In Vitro Techniques; Nitric Oxide; Pulmonary Artery; Vasodilation | 1992 |
Effect of systemic L-arginine administration on hemodynamics and nitric oxide release in man.
Topics: Adult; Amino Acids; Arginine; Blood Pressure; Cyclic GMP; Heart Rate; Hemodynamics; Hormones; Humans; Male; Nitric Oxide; Nitrites | 1992 |
Endothelium-dependent and independent cGMP mechanisms appear to mediate O2 responses in calf pulmonary resistance arteries.
Topics: Acetylcholine; Aminoquinolines; Animals; Arginine; Cattle; Cyclic GMP; Endothelium, Vascular; Hypoxia; Indomethacin; Nitroarginine; Oxygen; Partial Pressure; Prostaglandin Antagonists; Pulmonary Artery; Vascular Resistance; Vasoconstriction; Vasodilation | 1992 |
Nitric oxide alters renal function and guanosine 3',5'-cyclic monophosphate.
Topics: Animals; Arginine; Cyclic GMP; Dialysis; Dogs; Extracellular Space; Female; Hemodynamics; Injections; Kidney; Nitric Oxide; omega-N-Methylarginine; Renal Circulation | 1992 |
Nitric oxide does not mediate the neurotrophic effects of excitatory amino acids in cultured cerebellar granule neurons.
Topics: Animals; Arginine; Cell Survival; Cells, Cultured; Cerebellum; Cyclic GMP; Drug Stability; Kainic Acid; N-Methylaspartate; Nitric Oxide; Nitroarginine; Penicillamine; Rats; Rats, Inbred Strains; S-Nitroso-N-Acetylpenicillamine | 1992 |
Any physiological role for prostacyclin in regulation of fetal vessel tone?
Topics: 6-Ketoprostaglandin F1 alpha; Arginine; Blood Vessels; Bradykinin; Cyclic GMP; Endothelium, Vascular; Epoprostenol; Female; Fetus; Humans; In Vitro Techniques; Indomethacin; Isometric Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Pregnancy; Serotonin; Umbilical Arteries | 1992 |
Role of cGMP mechanisms in response of rat pulmonary arteries to hypoxia.
Topics: Aminoquinolines; Animals; Arginine; Cyclic GMP; Hypoxia; In Vitro Techniques; Indomethacin; Male; Nitroarginine; Pulmonary Artery; Purinones; Rats; Rats, Inbred Strains | 1992 |
Effects of L-NG-monomethyl arginine on the cyclic GMP formations in rat mesenteric arteries.
Topics: Animals; Arginine; Cyclic GMP; Male; Mesenteric Arteries; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains | 1992 |
Involvement of the nitric oxide-cyclic GMP pathway in the desensitization of bradykinin responses of cultured rat sensory neurons.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Arginine; Binding, Competitive; Bradykinin; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Drug Synergism; Drug Tolerance; Electric Conductivity; Ganglia, Spinal; Neurons, Afferent; Nitric Oxide; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Rats | 1992 |
L-arginine-dependent killing of intracellular Ehrlichia risticii by macrophages treated with gamma interferon.
Topics: Animals; Arginine; Cyclic GMP; Deferoxamine; Ehrlichia; Female; Interferon-gamma; Macrophages; Mice; Nitric Oxide; Nitrites; Nitroprusside; omega-N-Methylarginine | 1992 |
Modulation of vascular tone by endothelin-1: role of preload, endothelial integrity and concentration of endothelin-1.
Topics: Animals; Aorta; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Endothelins; In Vitro Techniques; Indomethacin; Muscle, Smooth, Vascular; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Oxyhemoglobins; Rats; Rats, Inbred Strains; Vasoconstriction; Vasodilation | 1992 |
Role of endothelium in hypoxia-induced contraction of isolated rat pulmonary artery.
Topics: Animals; Arginine; Cyclic GMP; Endothelium, Vascular; Hypoxia; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; omega-N-Methylarginine; Pulmonary Artery; Rats | 1992 |
Nitric oxide is a mediator of hypoxic coronary vasodilatation. Relation to adenosine and cyclooxygenase-derived metabolites.
Topics: Adenosine; Animals; Arginine; Coronary Vessels; Cyclic GMP; Guinea Pigs; Hypoxia; In Vitro Techniques; Indomethacin; Male; Nitric Oxide; Vasodilation; Xanthines | 1992 |
Cultured astrocytoma cells generate a nitric oxide-like factor from endogenous L-arginine and glyceryl trinitrate: effect of E. coli lipopolysaccharide.
Topics: Arginine; Astrocytoma; Cyclic GMP; Escherichia coli; Humans; Indomethacin; Lipopolysaccharides; Nitric Oxide; Nitroglycerin; omega-N-Methylarginine; Platelet Aggregation; Tumor Cells, Cultured | 1992 |
L-arginine infusion induces hypotension and diuresis/natriuresis with concomitant increased urinary excretion of nitrite/nitrate and cyclic GMP in humans.
Topics: Adult; Arginine; Blood Pressure; Cyclic GMP; Diuresis; Heart Rate; Humans; Male; Natriuresis; Nitrates; Nitrites; Nitrogen Oxides; Vasodilation | 1992 |
Tetrahydrobiopterin induces vasodilation via enhancement of cGMP level.
Topics: Animals; Aorta, Thoracic; Arginine; Biopterins; Cyclic GMP; In Vitro Techniques; Methoxamine; Muscle Contraction; NG-Nitroarginine Methyl Ester; Radioimmunoassay; Rats; Vasodilation | 1992 |
Evidence for normal nitric oxide-mediated vasodilator tone in conscious rats with cirrhosis.
Topics: Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Hemodynamics; Liver Cirrhosis, Experimental; Male; Nitric Oxide; omega-N-Methylarginine; Osmolar Concentration; Rats; Rats, Sprague-Dawley; Reference Values; Vasodilation | 1992 |
Dissociation of nitric oxide generation and kainate-mediated neuronal degeneration in primary cultures of rat cerebellar granule cells.
Topics: Animals; Arginine; Azo Compounds; Cell Death; Cells, Cultured; Cerebellum; Cyclic GMP; Kainic Acid; Kinetics; Magnesium; Nerve Degeneration; Neurons; Nitric Oxide; Nitroarginine; Rats; Rats, Wistar | 1992 |
Properties of an endogenous arachidonic acid--elicited relaxing mechanism in human placental vessels.
Topics: Arachidonic Acid; Arginine; Blood Vessels; Cyclic GMP; Endothelium, Vascular; Female; Humans; Nitric Oxide; Placenta; Pregnancy; Proadifen; Vasodilation | 1992 |
Involvement of nitric oxide in growth hormone (GH)-releasing hormone-induced GH secretion in rat pituitary cells.
Topics: Animals; Arginine; Cells, Cultured; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Growth Hormone; Growth Hormone-Releasing Hormone; Hemoglobins; Male; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Pituitary Gland, Anterior; Potassium; Radioimmunoassay; Rats; Rats, Wistar | 1992 |
Analgesia by direct antagonism of nociceptor sensitization involves the arginine-nitric oxide-cGMP pathway.
Topics: Acyclic Monoterpenes; Analgesics; Animals; Arginine; Bucladesine; Cyclic AMP; Cyclic GMP; Dipyrone; Male; Monoterpenes; Nitric Oxide; Nociceptors; omega-N-Methylarginine; Phthalazines; Rats; Rats, Wistar; Terpenes | 1992 |
Nitric oxide formation caused by Ca2+ release from internal stores in neuronal cell line is enhanced by cyclic AMP.
Topics: Animals; Arginine; Bradykinin; Calcium; Colforsin; Cyclic AMP; Cyclic GMP; Mice; Neurons; Nitric Oxide; Rats; Serotonin; Tumor Cells, Cultured | 1992 |
Arachidonic acid- and acetylcholine-induced relaxations of rabbit aorta.
Topics: Acetylcholine; Animals; Aorta; Arachidonic Acid; Arginine; Bridged Bicyclo Compounds, Heterocyclic; Cyclic GMP; Fatty Acids, Unsaturated; Hydrazines; Indomethacin; Male; Masoprocol; Metyrapone; Nitroarginine; Rabbits; Receptors, Thromboxane; Vasodilation | 1992 |
Endogenously synthesized nitric oxide prevents endotoxin-induced glomerular thrombosis.
Topics: Animals; Arginine; Blood Pressure; Cyclic GMP; Kidney Glomerulus; Lipopolysaccharides; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Proteinuria; Rats; Rats, Sprague-Dawley; Thrombosis | 1992 |
The molecular mechanism of central analgesia induced by morphine or carbachol and the L-arginine-nitric oxide-cGMP pathway.
Topics: Analgesia; Animals; Arginine; Brain; Carbachol; Cyclic GMP; Dinoprostone; Male; Molsidomine; Morphine; Nitric Oxide; Ornithine; Phthalazines; Rats; Rats, Wistar | 1992 |
Converting enzyme inhibitor-stimulated formation of nitric oxide and prostacyclin in endothelial cells from bovine aorta is mediated by endothelium-derived bradykinin.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Arginine; Bradykinin; Captopril; Cattle; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Epoprostenol; Nitric Oxide; Nitroarginine; Ramipril | 1992 |
Characterization of noradrenaline-stimulated cyclic GMP formation in brain astrocytes in culture.
Topics: Animals; Arginine; Astrocytes; Brain; Calcium; Cells, Cultured; Cyclic GMP; Hemoglobins; In Vitro Techniques; Norepinephrine; omega-N-Methylarginine; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Sympatholytics; Sympathomimetics; Virulence Factors, Bordetella | 1992 |
Involvement of cyclic GMP in non-adrenergic, non-cholinergic inhibitory neurotransmission in dog proximal colon.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Arginine; Autonomic Nervous System; Colon; Cyclic GMP; Dogs; Electric Stimulation; Female; Gastrointestinal Motility; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Purinones; Signal Transduction; Synaptic Transmission | 1992 |
Role of the L-arginine-NO pathway and of cyclic GMP in electrical field-induced noradrenaline release and vasoconstriction in the rat tail artery.
Topics: Animals; Arginine; Arteries; Atrial Natriuretic Factor; Cyclic GMP; Electric Stimulation; Endothelium, Vascular; In Vitro Techniques; Male; Methylene Blue; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Purinones; Rats; Tail; Vasoconstriction; Vasodilator Agents | 1992 |
Interleukin 1 beta induces the formation of nitric oxide by beta-cells purified from rodent islets of Langerhans. Evidence for the beta-cell as a source and site of action of nitric oxide.
Topics: Aconitate Hydratase; Animals; Arginine; Cyclic GMP; Cycloheximide; Electron Spin Resonance Spectroscopy; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Interleukin-1; Islets of Langerhans; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Secretory Rate; Tumor Cells, Cultured | 1992 |
Renal and systemic effects of aminoacids administered separately: comparison between L-arginine and non-nitric oxide donor aminoacids.
Topics: Amino Acids; Animals; Arginine; Atrial Natriuretic Factor; Atropine; Blood Pressure; Cyclic GMP; Diuresis; Glycine; Kidney; Male; Natriuresis; Nitric Oxide; Nitroarginine; Rats; Rats, Wistar | 1992 |
Novel signal transduction pathway mediating endothelium-dependent beta-adrenoceptor vasorelaxation in rat thoracic aorta.
Topics: Albuterol; Animals; Aorta, Thoracic; Arginine; Colforsin; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroarginine; Nitroprusside; Norepinephrine; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Signal Transduction | 1992 |
Role of nitric oxide and guanosine 3',5'-cyclic monophosphate in mediating nonadrenergic, noncholinergic relaxation in guinea-pig pulmonary arteries.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Arginine; Autonomic Nervous System; Cyclic GMP; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Oxidopamine; Phosphodiesterase Inhibitors; Purinones; Pyrogallol; Sympathectomy, Chemical | 1992 |
Evidence that nitric oxide mediates the cyclic GMP response to synaptic activity in the rat superior cervical ganglion.
Topics: Animals; Arginine; Cyclic GMP; Electric Stimulation; Ganglia, Sympathetic; Male; Nitric Oxide; Nitroarginine; Oxyhemoglobins; Rats; Rats, Sprague-Dawley; Synapses; Synaptic Transmission | 1992 |
NG-methyl-L-arginine decreases contractility, cGMP and cAMP in isoproterenol-stimulated rat hearts in vitro.
Topics: Animals; Arginine; Coronary Circulation; Cyclic AMP; Cyclic GMP; Heart; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardium; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley | 1992 |
Activation of endothelin ETB receptors increases glomerular cGMP via an L-arginine-dependent pathway.
Topics: Acetylcholine; Animals; Arginine; Atrial Natriuretic Factor; Binding, Competitive; Cyclic GMP; Endothelins; Kidney Glomerulus; Male; NG-Nitroarginine Methyl Ester; Peptide Fragments; Peptides, Cyclic; Rats; Rats, Sprague-Dawley; Receptors, Endothelin | 1992 |
Differential effect of L-nitroarginine methyl ester on urinary cGMP and kidney growth in the conscious rat following uninephrectomy.
Topics: Animals; Arginine; Cyclic GMP; Kidney; Male; Nephrectomy; NG-Nitroarginine Methyl Ester; Rats; Rats, Wistar | 1992 |
[Effect of NO-like relaxing factor (NO-LRF) in rat tourniquet shock].
Topics: Animals; Aorta; Arginine; Blood Pressure; Cyclic GMP; In Vitro Techniques; Male; Nitric Oxide; Nitroarginine; Rats; Rats, Wistar; Shock; Tourniquets; Vasodilator Agents | 1992 |
Possible mechanisms of age-associated reduction of vascular relaxation caused by atrial natriuretic peptide.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Aging; Animals; Aorta, Thoracic; Arginine; Atrial Natriuretic Factor; Cyclic GMP; Endothelium, Vascular; Guanylate Cyclase; Hemoglobins; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Purinones; Rats; Rats, Inbred Strains | 1992 |
NG-monomethyl-L-arginine and nitroarginine potentiate pressor responsiveness of vasoconstrictors in conscious rats.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta; Arginine; Blood Pressure; Cyclic GMP; Drug Synergism; Female; NG-Nitroarginine Methyl Ester; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Renin-Angiotensin System; Vasoconstrictor Agents | 1992 |
Involvement of nitric oxide pathway in the PAF-induced relaxation of rat thoracic aorta.
Topics: Aging; Animals; Aorta, Thoracic; Arginine; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Guanylate Cyclase; Hemoglobins; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Wistar | 1992 |
Biphasic 24-hour variations in cyclic GMP accumulation in the rat pineal gland are due to corresponding changes in the activity of cytosolic and particulate guanylate cyclase.
Topics: Animals; Arginine; Circadian Rhythm; Cyclic GMP; Cytosol; Enzyme Activation; Guanylate Cyclase; Male; Nitric Oxide; omega-N-Methylarginine; Pineal Gland; Rats; Rats, Sprague-Dawley; Time Factors | 1992 |
Increase in activating ability of human platelet guanylate cyclase during aggregation.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arginine; Blood Platelets; Cyclic GMP; Enzyme Activation; Guanylate Cyclase; Humans; Nitroprusside; Platelet Aggregation; Protoporphyrins | 1992 |
Nitric oxide mediated formation of cyclic GMP in the olfactory system.
Topics: Animals; Arginine; Cilia; Cyclic AMP; Cyclic GMP; Guanylate Cyclase; Hemoglobins; In Vitro Techniques; Nitric Oxide; Nitroarginine; Nitroprusside; Odorants; Olfactory Mucosa; Rats; Rats, Sprague-Dawley | 1992 |
Glutamate receptor agonists stimulate nitric oxide synthase in primary cultures of cerebellar granule cells.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Calcium; Cells, Cultured; Cerebellum; Citrulline; Cyclic GMP; Glutamates; Glutamic Acid; Granulocytes; Kainic Acid; N-Methylaspartate; Nitric Oxide Synthase; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter | 1992 |
Insulin secretion from pancreatic B cells caused by L-arginine-derived nitrogen oxides.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Calcium; Calmodulin; Cell Line; Cyclic GMP; Enzyme Activation; Glucose; Guanylate Cyclase; Insulin; Insulin Secretion; Islets of Langerhans; NADP; Nitric Oxide Synthase; Nitroarginine; Nitrogen Oxides; omega-N-Methylarginine; Rats | 1992 |
The role of nitric oxide in hippocampal long-term potentiation.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Calcium; Calmodulin; Cyclic GMP; Dibutyryl Cyclic GMP; Hemoglobins; Hippocampus; Male; Neuronal Plasticity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Synapses; Time Factors | 1992 |
Different receptors mediate stimulation of nitric oxide-dependent cyclic GMP formation in neurons and astrocytes in culture.
Topics: Amino Acid Oxidoreductases; Animals; Animals, Newborn; Arginine; Astrocytes; Brain; Calcimycin; Carbachol; Catecholamines; Cells, Cultured; Cyclic GMP; Embryo, Mammalian; Glutamates; Histamine; Hormones; Ionomycin; Kinetics; Neurons; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Receptors, Cell Surface | 1992 |
Nitric oxide but not prostacyclin is an autocrine endothelial mediator.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arginine; Calcimycin; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Dinoprostone; Endothelium, Vascular; Epoprostenol; Iloprost; Nitric Oxide; omega-N-Methylarginine; Second Messenger Systems; Swine | 1992 |
In vitro interaction between cerebellar astrocytes and granule cells: a putative role for nitric oxide.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Astrocytes; Calcimycin; Cell Communication; Cells, Cultured; Cerebellum; Citrulline; Cyclic GMP; Kinetics; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Rats | 1992 |
Induction of nitric oxide synthase by lipoteichoic acid from Staphylococcus aureus in vascular smooth muscle cells.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cells, Cultured; Cyclic GMP; Enzyme Induction; Kinetics; Lipopolysaccharides; Methylene Blue; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phenylephrine; Rats; Staphylococcus aureus; Teichoic Acids | 1992 |
Inhibitors of calmodulin impair the constitutive but not the inducible nitric oxide synthase activity in the rat aorta.
Topics: Amino Acid Oxidoreductases; Animals; Aorta; Arginine; Calmodulin; Cyclic GMP; Drug Interactions; Endothelium, Vascular; Fendiline; Imidazoles; Male; Molsidomine; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Inbred Strains; Vasodilator Agents | 1992 |
Stimulation of the nitric oxide synthase pathway in human hepatocytes by cytokines and endotoxin.
Topics: Amino Acid Oxidoreductases; Arginine; Cyclic GMP; Cytokines; Endotoxins; Humans; Lipopolysaccharides; Liver; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Recombinant Proteins | 1992 |
Balloon injury and interleukin-1 beta induce nitric oxide synthase activity in rat carotid arteries.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Carotid Arteries; Carotid Artery Injuries; Catheterization; Cyclic GMP; Endothelium, Vascular; In Vitro Techniques; Interleukin-1; Male; Nitric Oxide Synthase; Nitroarginine; Phenylephrine; Rats; Rats, Inbred Strains; Superoxide Dismutase | 1992 |
Endothelial cGMP does not regulate basal release of endothelium-derived relaxing factor in culture.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Atrial Natriuretic Factor; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Vasodilator Agents | 1992 |
Determinants of aortic cyclic guanosine monophosphate in hypertension induced by chronic inhibition of nitric oxide synthase.
Topics: Amino Acid Oxidoreductases; Animals; Aorta; Arginine; Atrial Natriuretic Factor; Blood Pressure; Body Weight; Cyclic GMP; Hypertension; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; Organ Size; Rats; Rats, Inbred Strains | 1992 |
Enhanced photorelaxation in aorta, pulmonary artery and corpus cavernosum produced by BAY K 8644 or N-nitro-L-arginine.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta; Arginine; Cavernous Sinus; Cyclic GMP; Dose-Response Relationship, Radiation; In Vitro Techniques; Light; Muscle, Smooth, Vascular; Nitroarginine; Pulmonary Artery; Rabbits; Ultraviolet Rays; Vasodilation | 1992 |
Characterization and localization of nitric oxide synthase in non-adrenergic non-cholinergic nerves from bovine retractor penis muscles.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blotting, Western; Calmodulin; Cattle; Cyclic GMP; Immunohistochemistry; Male; Nerve Tissue; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Penis | 1992 |
Nitric oxide and cyclic GMP formation induced by interleukin 1 beta in islets of Langerhans. Evidence for an effector role of nitric oxide in islet dysfunction.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Biological Transport; Cyclic GMP; Cycloheximide; Glucose; Interleukin-1; Islets of Langerhans; Male; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Oxidation-Reduction; Rats; Rats, Sprague-Dawley | 1992 |
Interferon-gamma inhibits proliferation of rat vascular smooth muscle cells by nitric oxide generation.
Topics: Amino Acid Oxidoreductases; Animals; Aorta; Arginine; Cell Division; Cells, Cultured; Cyclic GMP; DNA Replication; Interferon-gamma; Kinetics; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1992 |
A nitric oxide (NO) synthase inhibitor accelerates amygdala kindling.
Topics: Amino Acid Oxidoreductases; Amygdala; Animals; Arginine; Cyclic GMP; Epilepsy; Kindling, Neurologic; Male; Neuronal Plasticity; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Sprague-Dawley | 1992 |
Nitric oxide synthase responsible for L-arginine-induced relaxation of rat aortic rings in vitro may be an inducible type.
Topics: Amino Acid Oxidoreductases; Animals; Aorta, Thoracic; Arginine; Cyclic GMP; Dactinomycin; Dexamethasone; Enzyme Induction; Glucocorticoids; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Phenylephrine; Protein Biosynthesis; Rats; Rats, Wistar | 1992 |
Inhibition of inositol 1,4,5-trisphosphate formation by cyclic GMP in cultured aortic endothelial cells of the pig.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Arginine; Atrial Natriuretic Factor; Cells, Cultured; Cyclic GMP; Depression, Chemical; DNA; Endothelium, Vascular; Hemoglobins; Inosine Triphosphate; Nitroarginine; Nitroprusside; Swine; Thrombin | 1991 |
Generation of an endothelium-derived relaxing factor-like substance in bovine tracheal smooth muscle.
Topics: Animals; Arginine; Atropine; Carbachol; Cattle; Cyclic GMP; Hemoglobins; In Vitro Techniques; Kinetics; Methylene Blue; Muscle, Smooth; Nitric Oxide; Pyrogallol; Superoxide Dismutase; Superoxides; Trachea | 1991 |
NMDA receptor activation in rat hippocampus induces cyclic GMP formation through the L-arginine-nitric oxide pathway.
Topics: Animals; Arginine; Cyclic GMP; Hippocampus; In Vitro Techniques; Kinetics; N-Methylaspartate; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Rats; Receptors, N-Methyl-D-Aspartate | 1991 |
Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures.
Topics: Animals; Arginine; Cell Survival; Cells, Cultured; Citrulline; Cyclic GMP; Dizocilpine Maleate; Fetus; Glutamates; Hemoglobins; Hippocampus; Kinetics; N-Methylaspartate; Neurons; Neurotoxins; Nitric Oxide; Rats; Receptors, N-Methyl-D-Aspartate; Superoxide Dismutase | 1991 |
L-arginine induces relaxation of rat aorta possibly through non-endothelial nitric oxide formation.
Topics: Animals; Aorta, Thoracic; Arginine; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Hemoglobins; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroarginine; Rats; Rats, Inbred Strains | 1991 |
NG-nitro-L-arginine antagonizes endothelium-dependent dilator responses by inhibiting endothelium-derived relaxing factor release in the isolated rabbit heart.
Topics: Acetylcholine; Animals; Arginine; Blood Platelets; Coronary Vessels; Cyclic GMP; Endothelins; Endothelium, Vascular; Female; Heart; Male; Nitric Oxide; Nitroarginine; Nitroprusside; Pressure; Rabbits; Serotonin; Vasodilation | 1991 |
Histamine H1-receptor-mediated cyclic GMP production in guinea-pig lung tissue is an L-arginine-dependent process.
Topics: Animals; Arginine; Carbamates; Cyclic GMP; Guinea Pigs; Histamine; Histamine Antagonists; Lung; Male; Nitric Oxide; Phenylcarbamates; Receptors, Histamine H1; Signal Transduction | 1991 |
A simple and sensitive bioassay method for detection of EDRF with RFL-6 rat lung fibroblasts.
Topics: Animals; Arginine; Biological Assay; Bradykinin; Cell Line; Cyclic GMP; Fibroblasts; Lung; Nitric Oxide; omega-N-Methylarginine; Rats; Sensitivity and Specificity; Time Factors | 1991 |
Two mechanisms mediate relaxation by bradykinin of pig coronary artery: NO-dependent and -independent responses.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arginine; Bradykinin; Coronary Vessels; Cyclic GMP; Dose-Response Relationship, Drug; In Vitro Techniques; Methylene Blue; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Potassium; Prostaglandin Endoperoxides, Synthetic; Swine; Vasodilation | 1991 |
Role of nitric oxide in neurally induced cerebroarterial relaxation.
Topics: Animals; Arginine; Calcimycin; Cerebral Arteries; Cyclic GMP; Dogs; Female; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Neurons; Nicotine; Nitric Oxide; Nitroarginine; Nitroglycerin; Nitroprusside; Vasodilator Agents | 1991 |
The calcium channel antagonist S 11568 causes endothelium-dependent relaxation in canine arteries.
Topics: Animals; Arginine; Calcium Channel Blockers; Cyclic GMP; Dihydropyridines; Dogs; Endothelium, Vascular; Female; Hemoglobins; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine | 1991 |
Nitric oxide synthesis in endothelial cells: evidence for a pathway inducible by TNF-alpha.
Topics: Animals; Aorta; Arginine; Citrulline; Cyclic GMP; Endothelium, Vascular; Glomerular Mesangium; Lipopolysaccharides; Nitric Oxide; Renal Artery; Tumor Necrosis Factor-alpha | 1991 |
Mechanisms of renal effects of different agents stimulating production of cGMP.
Topics: Acetylcholine; Animals; Arginine; Atrial Natriuretic Factor; Cyclic GMP; Diuresis; Glomerular Filtration Rate; Hemodynamics; Kidney; Male; Natriuresis; Nitroarginine; Nitroprusside; Rats; Rats, Inbred Strains; Renal Circulation | 1991 |
Increased vascular responsiveness to bradykinin in kidneys of spontaneously hypertensive rats. Effect of N omega-nitro-L-arginine.
Topics: Acetylcholine; Animals; Arginine; Bradykinin; Cyclic GMP; Hypertension; Kidney; Nitric Oxide; Nitroarginine; Nitroprusside; Perfusion; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Vasodilation | 1991 |
L-arginine abrogates salt-sensitive hypertension in Dahl/Rapp rats.
Topics: Animals; Arginine; Blood Pressure; Citrulline; Cyclic GMP; Glomerular Filtration Rate; Hypertension; Nitric Oxide; omega-N-Methylarginine; Rats; Sodium Chloride | 1991 |
Nitric oxide derived from L-arginine impairs cytoplasmic pH regulation by vacuolar-type H+ ATPases in peritoneal macrophages.
Topics: Acid-Base Equilibrium; Animals; Arginine; Bicarbonates; Cyclic AMP; Cyclic GMP; Cytoplasm; Female; Hydrogen-Ion Concentration; In Vitro Techniques; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; omega-N-Methylarginine; Peritoneal Cavity; Proton-Translocating ATPases; Sodium; Vacuoles | 1991 |
Bradykinin and ATP stimulate L-arginine uptake and nitric oxide release in vascular endothelial cells.
Topics: Adenosine Triphosphate; Animals; Aorta; Arginine; Biological Transport; Bradykinin; Cell Line; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Kinetics; Nitric Oxide; Nitroarginine; Swine | 1991 |
Elevated guanosine 3':5'-cyclic monophosphate mediates the depression of nitrovasodilator reactivity in endothelium-intact blood vessels.
Topics: Animals; Aorta, Thoracic; Arginine; Cricetinae; Cyclic GMP; Endothelium, Vascular; Male; Mesocricetus; Nitric Oxide; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Sodium Nitrite; Vasodilator Agents | 1991 |
Role of nitric oxide and cyclic GMP as mediators of endothelium-independent neurogenic relaxation in bovine mesenteric artery.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Arginine; Cattle; Cyclic GMP; Electric Stimulation; Endothelium, Vascular; In Vitro Techniques; Mesenteric Arteries; Nervous System Physiological Phenomena; Nitric Oxide; Purinones; Vasodilation | 1991 |
Endothelium-independent contractions to NG-monomethyl-L-arginine in canine basilar artery.
Topics: Animals; Arginine; Basilar Artery; Cyclic GMP; Dogs; Dose-Response Relationship, Drug; Endothelium, Vascular; omega-N-Methylarginine; Osmolar Concentration; Vasoconstriction | 1991 |
Hypoxic contraction of canine coronary arteries: role of endothelium and cGMP.
Topics: Animals; Arginine; Coronary Vessels; Cyclic GMP; Dinoprost; Dogs; Endothelium, Vascular; Female; Hypoxia; In Vitro Techniques; Male; Methylene Blue; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Oxygen | 1991 |
Platelet inhibition by an L-arginine-derived substance released by IL-1 beta-treated vascular smooth muscle cells.
Topics: Animals; Aorta, Thoracic; Arginine; Blood Platelets; Cells, Cultured; Cyclic GMP; Drug Synergism; Interleukin-1; Methylene Blue; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Superoxide Dismutase; Thrombin | 1991 |
N omega-nitro-L-arginine methyl ester selectively inhibits pulmonary vasodilator responses to acetylcholine and bradykinin.
Topics: Acetylcholine; Alprostadil; Animals; Arginine; Bradykinin; Cats; Cyclic GMP; Female; Isoproterenol; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Pulmonary Circulation; Vasodilation | 1991 |
Endothelin increases cyclic GMP levels in LLC-PK1 porcine kidney epithelial cells via formation of an endothelium-derived relaxing factor-like substance.
Topics: Animals; Arginine; Calcium; Calcium Channel Blockers; Calcium Channels; Calmodulin; Cells, Cultured; Cyclic GMP; Endothelins; Epithelial Cells; Epithelium; Extracellular Space; Hemoglobins; Kidney; Nitric Oxide; Superoxide Dismutase; Swine | 1991 |
Endothelium-derived relaxing factor (EDRF). Production from L-arginine.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cattle; Cells, Cultured; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Isometric Contraction; Male; Methacholine Compounds; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Phenylephrine; Pulmonary Artery; Rabbits; Rats; Rats, Inbred Strains; Vasodilator Agents | 1991 |
N omega-nitro-L-arginine attenuates the accumulation of aortic cyclic GMP and the hypotension produced by zaprinast.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Analysis of Variance; Animals; Aorta, Abdominal; Arginine; Blood Pressure; Cyclic GMP; Hypotension; Male; Muscle, Smooth, Vascular; Nitroarginine; Purinones; Radioimmunoassay; Rats; Rats, Inbred SHR | 1991 |
The molecular mechanism of action of peripheral morphine analgesia: stimulation of the cGMP system via nitric oxide release.
Topics: Analgesia; Animals; Arginine; Cyclic GMP; Male; Methylene Blue; Molsidomine; Morphine; Nitric Oxide; Ornithine; Phthalazines; Rats; Rats, Inbred Strains | 1991 |
Modulation of agonist-induced calcium mobilisation in bovine aortic endothelial cells by phorbol myristate acetate and cyclic AMP but not cyclic GMP.
Topics: Animals; Aorta; Arginine; Bradykinin; Calcium; Calcium Channel Agonists; Cattle; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Isoproterenol; Nitroarginine; Nitroprusside; Tetradecanoylphorbol Acetate; Thrombin | 1991 |
The effect of inhibitors of nitric oxide biosynthesis and cyclic GMP formation on nerve-evoked relaxation of human cavernosal smooth muscle.
Topics: Arginine; Autonomic Nervous System; Cyclic GMP; Electric Stimulation; Guanethidine; Humans; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitroarginine; Penis; Synaptic Transmission | 1991 |
Modulation of electrical coupling between retinal horizontal cells by intracellular messengers.
Topics: Animals; Arginine; Carps; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Isoquinolines; Nitric Oxide; Photoreceptor Cells; Rana catesbeiana; Retina; Spectrometry, Fluorescence; Turtles | 1991 |
Stimulative effect of sodium nitroprusside on peristaltic reflex in isolated guinea pig ileal segments.
Topics: Animals; Arginine; Cyclic GMP; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Methylene Blue; Muscle Contraction; Neurons; Nitric Oxide; Nitroarginine; Nitroglycerin; Nitroprusside; Peristalsis; Stimulation, Chemical | 1991 |
Interleukin 1 induces prolonged L-arginine-dependent cyclic guanosine monophosphate and nitrite production in rat vascular smooth muscle cells.
Topics: Aminoquinolines; Animals; Arginine; Cells, Cultured; Cyclic GMP; Enzyme Activation; Guanylate Cyclase; Hemoglobins; Interleukin-1; Methylene Blue; Muscle, Smooth, Vascular; Nitrites; omega-N-Methylarginine; Protein Synthesis Inhibitors; Rats | 1991 |
N-hydroxylamine is not an intermediate in the conversion of L-arginine to an activator of soluble guanylate cyclase in neuroblastoma N1E-115 cells.
Topics: Animals; Arginine; Calcium; Cell Line; Cyclic GMP; Cytosol; Guanylate Cyclase; Hydroxylamine; Hydroxylamines; Kinetics; Mice; Neuroblastoma | 1991 |
Evidence that an L-arginine/nitric oxide dependent elevation of tissue cyclic GMP content is involved in depression of vascular reactivity by endotoxin.
Topics: Aminoquinolines; Animals; Arginine; Cyclic GMP; Endotoxins; Enzyme Activation; Guanylate Cyclase; In Vitro Techniques; Lipopolysaccharides; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Rats; Rats, Inbred Strains; SRS-A | 1991 |
L-arginine stimulates cyclic guanosine 3',5'-monophosphate formation in rat islets of Langerhans and RINm5F insulinoma cells: evidence for L-arginine:nitric oxide synthase.
Topics: Aminoquinolines; Animals; Arginine; Cyclic GMP; Glucose; Guanylate Cyclase; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Male; Methylene Blue; Nitroprusside; Pancreatic Neoplasms; Rats; Rats, Inbred Strains; Tumor Cells, Cultured | 1991 |
Release of endothelium-derived relaxing factor from pig cultured aortic endothelial cells, as assessed by changes in endothelial cell cyclic GMP content, is inhibited by a phorbol ester.
Topics: Adenosine Triphosphate; Animals; Aorta, Thoracic; Arginine; Calcimycin; Catalase; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Hemoglobins; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Phorbol 12,13-Dibutyrate; Substance P; Superoxide Dismutase; Swine | 1990 |
Inhibition of nitric oxide synthase blocks N-methyl-D-aspartate-, quisqualate-, kainate-, harmaline-, and pentylenetetrazole-dependent increases in cerebellar cyclic GMP in vivo.
Topics: Alkaloids; Amino Acid Oxidoreductases; Amino Acids; Animals; Arginine; Cerebellum; Cyclic GMP; Dose-Response Relationship, Drug; Harmaline; Male; Mice; Mice, Inbred Strains; Nitric Oxide Synthase; omega-N-Methylarginine; Pentylenetetrazole; Receptors, Amino Acid; Receptors, Cell Surface | 1990 |
An L-arginine/nitric oxide pathway present in human platelets regulates aggregation.
Topics: Amino Acid Oxidoreductases; Arginine; Blood Platelets; Cyclic GMP; Cytosol; Enzyme Activation; Guanylate Cyclase; Homeostasis; Humans; Kinetics; Nitric Oxide; Nitric Oxide Synthase; Platelet Aggregation | 1990 |
Induction of nitric oxide synthase by cytokines in vascular smooth muscle cells.
Topics: Amino Acid Oxidoreductases; Animals; Aorta, Thoracic; Arginine; Biopterins; Cells, Cultured; Cyclic GMP; Cytokines; Enzyme Induction; In Vitro Techniques; Interferon-gamma; Interleukin-1; Muscle, Smooth, Vascular; NADP; Nitric Oxide; Nitric Oxide Synthase; Rabbits; Tumor Necrosis Factor-alpha | 1990 |
Endogenous nitric oxide release required for long-term synaptic depression in the cerebellum.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acid Oxidoreductases; Animals; Arginine; Cerebellum; Cyclic GMP; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamic Acid; Hemoglobins; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Potassium; Purkinje Cells; Pyridines; Quinoxalines; Rats; Rats, Inbred Strains; Synapses | 1991 |
Interleukin-1 beta induces the production of an L-arginine-derived relaxing factor from cultured smooth muscle cells from rat aorta.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Aorta, Thoracic; Arginine; Biological Assay; Cells, Cultured; Coronary Vessels; Cyclic GMP; Dogs; In Vitro Techniques; Indomethacin; Interleukin-1; Kinetics; Muscle, Smooth, Vascular; Rats; Rats, Inbred Strains; Stereoisomerism; Vasodilator Agents | 1991 |
Impairment of the L-arginine-nitric oxide pathway in mast cells from spontaneously hypertensive rats.
Topics: Animals; Arginine; Blood Platelets; Calcimycin; Cyclic AMP; Cyclic GMP; Histamine Release; Humans; In Vitro Techniques; Kinetics; Mast Cells; Nitric Oxide; omega-N-Methylarginine; p-Methoxy-N-methylphenethylamine; Platelet Aggregation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reference Values; Thrombin | 1991 |
Rat mast cells synthesize a nitric oxide like-factor which modulates the release of histamine.
Topics: Animals; Arginine; Blood Platelets; Cyclic GMP; Guanylate Cyclase; Histamine Release; Humans; Indomethacin; Male; Mast Cells; Nitric Oxide; omega-N-Methylarginine; Oxyhemoglobins; Platelet Aggregation; Rats; Rats, Inbred Strains; Superoxide Dismutase; Thrombin | 1991 |
Endothelial function of human gastroepiploic artery. Implications for its use as a bypass graft.
Topics: Arginine; Coronary Artery Bypass; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; In Vitro Techniques; Indomethacin; Nitroglycerin; omega-N-Methylarginine; Stomach; Substance P; Vascular Patency; Vasodilation | 1991 |
Effects of guanidino compounds on the endothelium-derived relaxing factor inhibitor NG-monomethyl L-arginine.
Topics: Animals; Aorta, Thoracic; Arginine; Cyclic GMP; Endothelium, Vascular; Guanidines; Homoarginine; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains | 1991 |
Absence of implication of L-arginine/nitric oxide pathway on neuronal cell injury induced by L-glutamate or hypoxia.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Brain; Cell Hypoxia; Cells, Cultured; Cyclic GMP; Dizocilpine Maleate; Fetus; Glutamates; Glutamic Acid; Kainic Acid; Kinetics; N-Methylaspartate; Neuroglia; Neurons; Nitric Oxide; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Quisqualic Acid; Rats | 1991 |
On the substrate specificity of nitric oxide synthase.
Topics: Amino Acid Oxidoreductases; Amino Acid Sequence; Animals; Arginine; Calcium; Cattle; Cell Line; Cyclic GMP; Endothelium; Endothelium, Vascular; Isoenzymes; Kidney; Lipopolysaccharides; Macrophages; Mice; Molecular Sequence Data; Monocytes; Nitric Oxide; Nitric Oxide Synthase; Peptides; Substrate Specificity; Swine | 1991 |
Participation of endothelium-derived relaxing factor and role of cyclic GMP in inhibitory effects of endothelium on contractile responses elicited by alpha-adrenoceptor agonists in rat aorta.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Arginine; Azepines; Clonidine; Cyclic GMP; Endothelium, Vascular; Female; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phenylephrine; Rats; Rats, Inbred Strains | 1991 |
Nitric oxide from vascular smooth muscle cells: regulation of platelet reactivity and smooth muscle cell guanylate cyclase.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Atrial Natriuretic Factor; Blood Platelets; Cattle; Cyclic GMP; Cycloheximide; Escherichia coli; Guanylate Cyclase; Humans; In Vitro Techniques; Lipopolysaccharides; Macrophages; Mice; Monocytes; Muscle, Smooth; Muscle, Smooth, Vascular; Nitric Oxide; Nitroglycerin; omega-N-Methylarginine; Superoxide Dismutase; Thrombin | 1991 |
Endothelin-1 stimulates cyclic GMP formation in porcine kidney epithelial cells via activation of the L-arginine-dependent soluble guanylate cyclase pathway.
Topics: Animals; Arginine; Calcium; Cell Line; Cyclic GMP; Endothelins; Epithelium; Guanylate Cyclase; Kidney; Stimulation, Chemical; Swine | 1991 |
Differential effect of cyclic GMP on the release of endothelin-1 from cultured endothelial cells and intact porcine aorta.
Topics: Animals; Aorta, Thoracic; Arginine; Cells, Cultured; Cyclic GMP; Endothelins; Endothelium, Vascular; In Vitro Techniques; Nitric Oxide; omega-N-Methylarginine; Radioimmunoassay; Swine; Thrombin | 1991 |
Nitric oxide synthesis in the CNS endothelium and macrophages differs in its sensitivity to inhibition by arginine analogues.
Topics: Animals; Arginine; Central Nervous System; Cyclic GMP; Endothelium; In Vitro Techniques; Macrophages; Mice; N-Methylaspartate; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Rats | 1991 |
Endothelial cyclic GMP and cyclic AMP do not regulate the release of endothelium-derived relaxing factor/nitric oxide from bovine aortic endothelial cells.
Topics: Animals; Aorta; Arginine; Calcimycin; Cattle; Cells, Cultured; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Epoprostenol; Nitric Oxide; Nitroarginine; Purinones | 1991 |
Development and mechanism of a specific supersensitivity to nitrovasodilators after inhibition of vascular nitric oxide synthesis in vivo.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Cyclic GMP; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroglycerin; Nitroprusside; omega-N-Methylarginine; Ornithine; Rats; Rats, Inbred Strains; Vasoconstriction; Vasodilation; Vasodilator Agents | 1991 |
Nitroarginine does not inhibit lysophosphatidylcholine (LPC)-induced vascular relaxation and accumulation of cyclic GMP.
Topics: Animals; Arginine; Calcimycin; Cattle; Cyclic GMP; Dose-Response Relationship, Drug; In Vitro Techniques; Lysophosphatidylcholines; Nitroarginine; Vasodilation | 1991 |
N omega-nitro-L-arginine attenuates endothelium-dependent pulmonary vasodilation in lambs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Adenosine Triphosphate; Animals; Arginine; Binding, Competitive; Blood Pressure; Cyclic GMP; Endothelium, Vascular; Hemodynamics; Hypertension, Pulmonary; Isoproterenol; Lung; Nitric Oxide; Nitroarginine; Nitroprusside; Prostaglandin Endoperoxides, Synthetic; Pulmonary Artery; Sheep; Vasodilation | 1991 |
Nanomolar N(G)-nitroarginine inhibits NMDA-induced cyclic GMP formation in rat cerebellum.
Topics: Animals; Arginine; Cerebellum; Cyclic GMP; In Vitro Techniques; N-Methylaspartate; Nitroarginine; Rats | 1990 |
Messengers mediating long-term desensitization in cerebellar Purkinje cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arginine; Cerebellum; Cyclic GMP; Egtazic Acid; Ibotenic Acid; In Vitro Techniques; omega-N-Methylarginine; Perfusion; Pertussis Toxin; Purkinje Cells; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Signal Transduction; Virulence Factors, Bordetella | 1990 |
[cGMP and neuronal function].
Topics: Amino Acid Sequence; Animals; Arachidonic Acids; Arginine; Cerebellum; Cyclic GMP; Guanylate Cyclase; Molecular Sequence Data; Neuroglia; Photoreceptor Cells; Signal Transduction | 1990 |
Synthesis of a nitric oxide-like factor from L-arginine by rat serosal mast cells: stimulation of guanylate cyclase and inhibition of platelet aggregation.
Topics: Animals; Arginine; Blood Platelets; Cyclic AMP; Cyclic GMP; Enzyme Activation; Guanylate Cyclase; Humans; In Vitro Techniques; Kinetics; Male; Mast Cells; Nitric Oxide; Platelet Aggregation Inhibitors; Rats; Rats, Inbred Strains; Superoxide Dismutase; Superoxides; Thrombin | 1990 |
N omega-nitro-L-arginine: a potent inhibitor of the L-arginine-dependent soluble guanylate cyclase activation pathway in LLC-PK1 cells.
Topics: Animals; Arginine; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Activation; Guanylate Cyclase; Nitroarginine; Oxytocin | 1990 |
EDRF release is a common pathway in the activation of guanylate cyclase by receptor agonists and calcium ionophores.
Topics: Arginine; Calcimycin; Calcium; Carbachol; Cells, Cultured; Cyclic GMP; Enzyme Activation; Guanylate Cyclase; Ionophores; Neuroblastoma; Nitric Oxide; omega-N-Methylarginine; Tumor Cells, Cultured | 1990 |
EDRF is an intracellular second messenger and autacoid to regulate cyclic GMP synthesis in many cells.
Topics: Animals; Arginine; Cell Line; Cells, Cultured; Cyclic GMP; Enzyme Activation; Fibroblasts; Guanylate Cyclase; Isoenzymes; Lung; Nitric Oxide; Organ Specificity; Oxidation-Reduction; Rats; Second Messenger Systems | 1990 |
Tumor necrosis factor alpha activates soluble guanylate cyclase in bovine glomerular mesangial cells via an L-arginine-dependent mechanism.
Topics: Animals; Arginine; Cattle; Cells, Cultured; Cyclic GMP; Cycloheximide; Dactinomycin; Enzyme Activation; Glomerular Mesangium; Guanylate Cyclase; Humans; Interferon-gamma; Interleukin-1; Kinetics; Nitrates; Nitrites; omega-N-Methylarginine; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1990 |
Peripheral analgesia and activation of the nitric oxide-cyclic GMP pathway.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Acetylcholine; Analgesia; Analgesics; Animals; Arginine; Cyclic GMP; Enzyme Activation; Guanylate Cyclase; Male; Nitric Oxide; Nociceptors; omega-N-Methylarginine; Rats; Rats, Inbred Strains | 1990 |
Release of endothelin from the porcine aorta. Inhibition by endothelium-derived nitric oxide.
Topics: Animals; Aorta; Arginine; Calcimycin; Cyclic GMP; Endothelins; Endothelium, Vascular; In Vitro Techniques; Nitric Oxide; omega-N-Methylarginine; Peptide Biosynthesis; Peptides; Superoxide Dismutase; Swine; Thrombin | 1990 |
Production of an EDRF-like activity in the cytosol of N1E-115 neuroblastoma cells.
Topics: Animals; Arginine; Cell-Free System; Cyclic GMP; Cytosol; Kinetics; Mice; Neuroblastoma; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Tumor Cells, Cultured | 1990 |
N omega-nitro-L-arginine: a potent inhibitor of endothelium-derived relaxing factor formation.
Topics: Adenosine Triphosphate; Animals; Arginine; Calcimycin; Cattle; Cyclic GMP; Depression, Chemical; Fibroblasts; In Vitro Techniques; Melitten; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Rats; Superoxide Dismutase | 1990 |
Role of endothelium-derived relaxing factor in regulation of renal hemodynamic responses.
Topics: Acetylcholine; Animals; Arginine; Blood Pressure; Cyclic GMP; Endothelium, Vascular; Hemodynamics; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Renal Circulation | 1990 |
Selective blockade of receptor-mediated cyclic GMP formation in N1E-115 neuroblastoma cells by an inhibitor of nitric oxide synthesis.
Topics: Animals; Arginine; Bradykinin; Carbachol; Cyclic GMP; Histamine; Mice; Neuroblastoma; Neurotensin; Nitric Oxide; omega-N-Methylarginine; Phosphatidylinositols; Receptors, Drug; Tumor Cells, Cultured | 1990 |
NG-amino-L-arginine: a new potent antagonist of L-arginine-mediated endothelium-dependent relaxation.
Topics: Animals; Arginine; Cattle; Cyclic GMP; Endothelium; Muscle Contraction; Muscle, Smooth; Pulmonary Artery | 1990 |
Mechanism of stimulation of cyclic-GMP level in a neuronal cell line mediated by serotonin (5-HT3) receptors. Involvement of nitric oxide, arachidonic-acid metabolism and cytosolic Ca2+.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Arginine; Bradykinin; Calcium; Calcium Channel Blockers; Cell Line; Cyclic GMP; Cytosol; Hemoglobins; Mice; Neurons; Nitric Oxide; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists | 1990 |
NG-methyl-L-arginine causes endothelium-dependent contraction and inhibition of cyclic GMP formation in artery and vein.
Topics: Acetylcholine; Animals; Arginine; Bradykinin; Cattle; Cyclic GMP; Endothelium, Vascular; In Vitro Techniques; Kinetics; Muscle, Smooth, Vascular; omega-N-Methylarginine; Oxyhemoglobins; Phenylephrine; Pulmonary Artery; Pulmonary Veins; Vasoconstriction | 1990 |
Nitric oxide and cyclic GMP formation upon electrical field stimulation cause relaxation of corpus cavernosum smooth muscle.
Topics: Animals; Arginine; Atropine; Cyclic GMP; Electric Stimulation; Guanethidine; Male; Membrane Potentials; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Penis; Potassium; Rabbits; Synaptic Transmission; Tetrodotoxin | 1990 |
Incubation with endotoxin activates the L-arginine pathway in vascular tissue.
Topics: Animals; Aorta, Thoracic; Arginine; Cyclic GMP; Endotoxins; In Vitro Techniques; Kinetics; Lipopolysaccharides; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Stereoisomerism | 1990 |
NG-monomethyl L-arginine inhibits endothelium-derived relaxing factor-stimulated cyclic GMP accumulation in cocultures of endothelial and vascular smooth muscle cells by an action specific to the endothelial cell.
Topics: Adenosine Triphosphate; Animals; Arginine; Bradykinin; Calcimycin; Cattle; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Melitten; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Pulmonary Artery | 1990 |
L-arginine-dependent vascular smooth muscle relaxation and cGMP formation.
Topics: Animals; Arginine; Cattle; Cyclic GMP; Endothelium, Vascular; Microscopy, Electron, Scanning; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Pulmonary Artery | 1990 |
Cloned murine T lymphocytes synthesize a molecule with the biological characteristics of nitric oxide.
Topics: Animals; Arginine; Cell Line; Clone Cells; Cyclic GMP; Nitric Oxide; Nitrites; Platelet Aggregation; Rats; T-Lymphocytes; Thrombin | 1990 |
Evidences for the existence of endothelium-derived relaxing factor in the renal medulla.
Topics: Acetylcholine; Animals; Arginine; Cyclic GMP; Dogs; Female; Kidney Medulla; Male; Molsidomine; Nitric Oxide; omega-N-Methylarginine; Premedication | 1990 |
L-arginine, but not N alpha-benzoyl-L-arginine ethyl ester, is a precursor of endothelium-derived relaxing factor.
Topics: Acetylcholine; Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Guinea Pigs; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitrates; Nitric Acid; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Pulmonary Artery | 1990 |
Stimulation of cyclic GMP production in cultured endothelial cells of the pig by bradykinin, adenosine diphosphate, calcium ionophore A23187 and nitric oxide.
Topics: Adenosine Diphosphate; Animals; Arginine; Bradykinin; Calcimycin; Cells, Cultured; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; In Vitro Techniques; Kinetics; Methylene Blue; Nitric Oxide; omega-N-Methylarginine; Oxyhemoglobins; Stimulation, Chemical; Superoxide Dismutase; Superoxides; Swine | 1990 |
Nitric oxide from L-arginine stimulates the soluble guanylate cyclase in adrenal glands.
Topics: Adrenal Cortex; Adrenal Glands; Adrenal Medulla; Amino Acid Oxidoreductases; Animals; Arginine; Calcium; Cattle; Cyclic GMP; Cytosol; Guanylate Cyclase; Kinetics; Male; NADP; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Inbred Strains | 1989 |
Role of the endothelium and arginine peptides on the vaso-motor response of porcine internal mammary artery.
Topics: Animals; Arginine; Cyclic GMP; Endothelins; Endothelium, Vascular; Mammary Arteries; Peptides; Swine; Thoracic Arteries; Vasoconstrictor Agents; Vasodilator Agents; Vasomotor System | 1989 |
Inhibition of chemotaxis Ng-monomethyl-L-arginine: a role for cyclic GMP.
Topics: Arginine; Blood Bactericidal Activity; Chemotaxis, Leukocyte; Cyclic GMP; Dibutyryl Cyclic GMP; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Nitric Oxide; omega-N-Methylarginine | 1989 |
A kainate receptor linked to nitric oxide synthesis from arginine.
Topics: Animals; Arginine; Cerebellum; Cyclic GMP; In Vitro Techniques; Kainic Acid; Kinetics; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Receptors, Kainic Acid; Receptors, Neurotransmitter | 1989 |
NMDA receptor activation induces nitric oxide synthesis from arginine in rat brain slices.
Topics: Animals; Arginine; Biotransformation; Brain; Cerebellum; Cyclic GMP; In Vitro Techniques; Neurons; Nitric Oxide; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
Cyclic GMP stimulation by vasopressin in LLC-PK1 kidney epithelial cells is L-arginine-dependent.
Topics: Arginine; Calcimycin; Cell Line; Cyclic GMP; Epithelial Cells; Kidney; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Vasopressins | 1989 |
Formation of nitric oxide from L-arginine in the central nervous system: a transduction mechanism for stimulation of the soluble guanylate cyclase.
Topics: Animals; Arginine; Brain; Citrulline; Cyclic GMP; Cytosol; Guanylate Cyclase; Kinetics; Male; Nitric Oxide; Rats; Signal Transduction; Synaptosomes | 1989 |
Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum.
Topics: Animals; Arginine; Aspartic Acid; Cerebellum; Citrulline; Cyclic GMP; Glutamates; Glutamic Acid; Hemoglobins; In Vitro Techniques; Kainic Acid; Kinetics; N-Methylaspartate; Nitric Oxide; omega-N-Methylarginine; Oxadiazoles; Quisqualic Acid; Rats | 1989 |
Effect of arginine salt of thioproline (thiazolidine carboxylate) on cyclic nucleotides of cerebral tumour.
Topics: Arginine; Brain Chemistry; Brain Neoplasms; Cyclic AMP; Cyclic GMP; Humans; Thiazoles; Thiazolidines | 1980 |
Thrombin stimulation of guanosine 3',5'-monophosphate formation in murine neuroblastoma cells (clone N1E-115).
Topics: Animals; Arginine; Blood Platelets; Catechols; Clone Cells; Cyclic GMP; Dansyl Compounds; Hirudins; Indomethacin; Masoprocol; Mice; Neuroblastoma; Thrombin; Trypsin | 1983 |
Simultaneous manipulation of the nitric oxide and prostanoid pathways reduces myocardial reperfusion injury.
Topics: Animals; Arginine; Aspirin; Cardioplegic Solutions; Coronary Circulation; Cyclic GMP; Glucose; Heart; Heart Rate; Hydroxyl Radical; In Vitro Techniques; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandins; Rats; Rats, Sprague-Dawley; Tromethamine; Vascular Resistance | 1995 |
Intrauterine hypoxia-ischemia increases N-methyl-D-aspartate-induced cGMP formation and glutamate accumulation in cultured rat cerebellar granule cells.
Topics: Animals; Arginine; Brain Ischemia; Cells, Cultured; Cerebellar Diseases; Chronic Disease; Cyclic GMP; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Fetal Hypoxia; Gestational Age; Glutamic Acid; Hypoxia, Brain; Kainic Acid; N-Methylaspartate; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley | 1995 |
Role of NO mechanism in cardiovascular effects of diaspirin cross-linked hemoglobin in anesthetized rats.
Topics: Animals; Arginine; Arteries; Aspirin; Cardiovascular System; Cyclic GMP; Gases; Hemodynamics; Hemoglobins; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Sodium Chloride; Vascular Resistance | 1995 |
Role of cyclic GMP in the control of capacitative Ca2+ entry in rat pancreatic acinar cells.
Topics: Aminoquinolines; Animals; Arginine; Biological Transport; Calcium; Calcium Channels; Calcium-Transporting ATPases; Cyclic GMP; Enzyme Inhibitors; Fura-2; Guanylate Cyclase; Methacholine Chloride; Muscarinic Agonists; Nitric Oxide Synthase; Nitroarginine; Pancreas; Rats; Rats, Sprague-Dawley; Terpenes; Thapsigargin | 1995 |
NMDA-dependent prostaglandin E2 release by human cultured astroglial cells is driven by nitric oxide.
Topics: Arachidonic Acid; Arginine; Astrocytes; Astrocytoma; Cell Line; Cyclic GMP; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Kinetics; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroprusside; Oxyhemoglobins; Receptors, N-Methyl-D-Aspartate; Tumor Cells, Cultured | 1995 |
Contrasting effect of antihypertensive treatment on the renal response to L-arginine.
Topics: Adrenergic beta-Antagonists; Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Arginine; Atenolol; Calcium Channel Blockers; Cyclic GMP; Data Interpretation, Statistical; Female; Humans; Hypertension; Infusions, Parenteral; Kidney; Male; Middle Aged; Nitric Oxide; Renal Circulation; Time Factors | 1995 |
A cellular mechanism for nitric oxide-mediated cholinergic control of mammalian heart rate.
Topics: 1-Methyl-3-isobutylxanthine; Aminoquinolines; Animals; Arginine; Carbachol; Cardiotonic Agents; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Enzyme Inhibitors; GTP-Binding Proteins; Guanylate Cyclase; Heart Rate; Isoproterenol; Methylene Blue; Molsidomine; Muscarinic Agonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Aggregation Inhibitors; Rabbits; Receptors, Cholinergic; Receptors, Muscarinic; Sinoatrial Node; Thionucleotides | 1995 |
Barium and strontium can substitute for calcium in stimulating nitric oxide production in the endothelium of canine coronary arteries.
Topics: Animals; Arginine; Barium; Calcium; Cations, Divalent; Coronary Vessels; Cyclic GMP; Dogs; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Isometric Contraction; Muscle Relaxation; Neurotransmitter Agents; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Potassium; Strontium | 1995 |
Novel guanylyl cyclase inhibitor, ODQ reveals role of nitric oxide, but not of cyclic GMP in endothelin-1 secretion.
Topics: Animals; Arginine; Calcium; Cells, Cultured; Cyclic GMP; Endothelins; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Oxadiazoles; Quinoxalines; Swine; Terpenes; Thapsigargin | 1995 |
Role of nitric oxide in adenosine receptor-mediated relaxation of porcine coronary artery.
Topics: Aminoquinolines; Animals; Arginine; Coronary Vessels; Cyclic GMP; Male; Nitric Oxide; Nitrites; omega-N-Methylarginine; Receptors, Purinergic P1; Swine; Vasodilation; Vasodilator Agents | 1995 |
Role of nitric oxide synthesis in salt-sensitive hypertension in Dahl/Rapp rats.
Topics: Analysis of Variance; Animals; Arginine; Blood Pressure; Citrulline; Cyclic GMP; Dexamethasone; Disease Models, Animal; Homoarginine; Hypertension; Insulin; Male; Nitrates; Nitric Oxide; Ornithine; Rats; Rats, Inbred Strains | 1993 |
A selective agonist of endothelin type B receptor, IRL 1620, stimulates cyclic GMP increase via nitric oxide formation in rat aorta.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Aorta, Thoracic; Arginine; Binding Sites; Calcium; Cyclic GMP; Cytosol; Drug Interactions; Endothelins; Endothelium, Vascular; Kinetics; Male; Membranes; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Peptide Fragments; Peptides, Cyclic; Rats; Rats, Wistar; Receptors, Endothelin; Stimulation, Chemical; Time Factors | 1993 |
NG-nitro-L-arginine methyl ester does not affect balloon catheter-induced intimal hyperplasia in rats.
Topics: Acetylcholine; Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Carotid Arteries; Carotid Artery Injuries; Catheterization; Cyclic GMP; Dose-Response Relationship, Drug; Hyperplasia; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Tunica Intima | 1993 |
Chronic administration of a nitric oxide synthase inhibitor, N omega-nitro-L-arginine, and drug-induced increase in cerebellar cyclic GMP in vivo.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cerebellum; Cyclic GMP; Drug Interactions; Glutamates; Glutamic Acid; Harmaline; Male; Mice; Nitric Oxide Synthase; Nitroarginine; Pentylenetetrazole; Picrotoxin | 1993 |
Interleukin 1 activates soluble guanylate cyclase in human vascular smooth muscle cells through a novel nitric oxide-independent pathway.
Topics: Amino Acid Oxidoreductases; Aminoquinolines; Animals; Arginine; Base Sequence; Catecholamines; Cells, Cultured; Cyclic GMP; DNA Primers; Enzyme Activation; Guanylate Cyclase; Humans; Imidazolines; Interferon-gamma; Interleukin-1; Lipopolysaccharides; Methylene Blue; Molecular Sequence Data; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Polymerase Chain Reaction; Rats; RNA, Messenger; Tumor Necrosis Factor-alpha | 1994 |
Long-term depression requires nitric oxide and guanosine 3':5' cyclic monophosphate production in rat cerebellar Purkinje cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amino Acid Oxidoreductases; Animals; Arginine; Cyclic GMP; In Vitro Techniques; Long-Term Potentiation; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Purkinje Cells; Rats; Time Factors | 1993 |
Impaired nitric oxide-dependent cyclic guanosine monophosphate generation in glomeruli from diabetic rats. Evidence for protein kinase C-mediated suppression of the cholinergic response.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alkaloids; Amino Acid Oxidoreductases; Animals; Arginine; Calcimycin; Carbachol; Cyclic GMP; Diabetes Mellitus, Experimental; Female; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Isoquinolines; Kidney Glomerulus; Kinetics; Membrane Proteins; Myristoylated Alanine-Rich C Kinase Substrate; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phosphates; Phosphorylation; Piperazines; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Proteins; Rats; Rats, Sprague-Dawley; Staurosporine; Thromboxane A2 | 1994 |
Laminar flow stimulates ATP- and shear stress-dependent nitric oxide production in cultured bovine endothelial cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Animals; Aorta, Thoracic; Arginine; Calcium; Cattle; Cells, Cultured; Cyclic GMP; Egtazic Acid; Endothelium, Vascular; Fetus; Kinetics; Nitric Oxide; omega-N-Methylarginine; Stress, Mechanical | 1994 |
An L-arginine-nitric oxide-cyclic guanosine monophosphate system exists in the uterus and inhibits contractility during pregnancy.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Citrulline; Culture Techniques; Cyclic GMP; Dose-Response Relationship, Drug; Female; Labor, Obstetric; Methylene Blue; NADP; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroprusside; Pregnancy; Progesterone; Rats; Rats, Sprague-Dawley; Uterine Contraction; Uterus | 1994 |
Eclosion hormone-mediated signal transduction in the silkworm abdominal ganglia: involvement of a cascade from inositol(1,4,5)trisphosphate to cyclic GMP.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Bombyx; Calcium; Citrulline; Cyclic GMP; Egtazic Acid; Enzyme Activation; Ganglia, Invertebrate; Inositol 1,4,5-Trisphosphate; Insect Hormones; Neomycin; Nitric Oxide Synthase; Nitroarginine; p-Methoxy-N-methylphenethylamine; Second Messenger Systems; Signal Transduction; Sulfonamides | 1994 |
Endothelium-derived bradykinin: implications for angiotensin-converting enzyme-inhibitor therapy.
Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Bradykinin; Calcium; Cattle; Cells, Cultured; Coronary Vessels; Cyclic GMP; Endothelium, Vascular; Epoprostenol; Humans; Isoquinolines; Nitric Oxide; Nitroarginine; Ramipril; Tetrahydroisoquinolines; Umbilical Veins; Vasodilation | 1993 |
Organic nitrates and compounds that increase intraplatelet cyclic guanosine monophosphate (cGMP) levels enhance the antiaggregating effects of the stable prostacyclin analogue iloprost.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Diphosphate; Adult; Arginine; Blood Platelets; Collagen; Cyclic AMP; Cyclic GMP; Drug Synergism; Endothelium, Vascular; Epinephrine; Humans; Iloprost; Intracellular Fluid; Male; Nitroglycerin; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Factor 4; Second Messenger Systems | 1993 |
Nitric oxide, superoxide and peroxynitrite: putative mediators of NMDA-induced cell death in cerebellar granule cells.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Catalase; Cell Death; Cells, Cultured; Cerebellum; Cyclic GMP; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Mice; Molsidomine; N-Methylaspartate; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Receptors, N-Methyl-D-Aspartate; Superoxide Dismutase; Superoxides; Xanthine Oxidase | 1993 |
Lack of involvement of nitric oxide in NMDA-induced neuronal cell death in cortical culture.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Death; Cells, Cultured; Cerebral Cortex; Cyclic GMP; Models, Neurological; N-Methylaspartate; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rats | 1993 |
Endothelin (ET)-3 stimulates cyclic guanosine 3',5'-monophosphate production via ETB receptor by producing nitric oxide in isolated rat glomerulus, and in cultured rat mesangial cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Calmodulin; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Egtazic Acid; Endothelin Receptor Antagonists; Endothelins; Glomerular Mesangium; Guanylate Cyclase; Hemoglobins; In Vitro Techniques; Kidney Glomerulus; Kinetics; Male; Methylene Blue; Nicardipine; Nitric Oxide; omega-N-Methylarginine; Peptide Fragments; Peptides, Cyclic; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; Sulfonamides | 1994 |
Induction of nitric oxide release by interferon-gamma inhibits vasodilation and cyclic GMP increase in bovine isolated mesenteric arteries.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Cattle; Cyclic GMP; In Vitro Techniques; Interferon-gamma; Mesenteric Arteries; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Vasodilation | 1994 |
Acute and prolonged hypoxia attenuate endothelial nitric oxide production in rat pulmonary arteries by different mechanisms.
Topics: Acetylcholine; Amino Acid Oxidoreductases; Animals; Arginine; Calcimycin; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Hypoxia; In Vitro Techniques; Male; Nitric Oxide; Nitric Oxide Synthase; Oxygen Consumption; Pulmonary Artery; Rats; Rats, Sprague-Dawley | 1993 |
Involvement of nitric oxide in the regulation of gonadotropin-releasing hormone release from the GT1-1 neuronal cell line.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Line; Cyclic GMP; Gonadotropin-Releasing Hormone; Mice; Mice, Transgenic; Molsidomine; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Norepinephrine; Sodium Nitrite | 1994 |
Smooth muscle cell responsiveness to nitrovasodilators in hypertensive and normotensive rats.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Base Sequence; Blotting, Northern; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Guanylate Cyclase; Hypertension; Male; Molecular Sequence Data; Muscle, Smooth, Vascular; Nitric Oxide; Nitroglycerin; Nitroprusside; Oligonucleotide Probes; omega-N-Methylarginine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA, Messenger; Vasodilation | 1994 |
Interleukin-4 stimulates cGMP production by IFN-gamma-activated human monocytes. Involvement of the nitric oxide synthase pathway.
Topics: Amino Acid Oxidoreductases; Aminoquinolines; Arginine; Calcium; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Egtazic Acid; Guanylate Cyclase; Humans; Interferon-gamma; Interleukin-4; Kinetics; Leukocytes, Mononuclear; Methylene Blue; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine | 1994 |
N omega-nitro-L-arginine inhibits vasodilations and elevations of both cyclic AMP and cyclic GMP levels in rat aorta induced by calcitonin gene-related peptide (CGRP).
Topics: Amino Acid Oxidoreductases; Animals; Aorta; Arginine; Calcitonin Gene-Related Peptide; Cyclic AMP; Cyclic GMP; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Sprague-Dawley; Vasodilation | 1994 |
Chronic inhibition of nitric oxide production accelerates neointima formation and impairs endothelial function in hypercholesterolemic rabbits.
Topics: Amino Acid Oxidoreductases; Animals; Aorta; Arginine; Arteriosclerosis; Cyclic GMP; Endothelium, Vascular; Hypercholesterolemia; Lipid Peroxidation; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rabbits; Vasodilation | 1994 |
Involvement of nitric oxide and cyclic GMP in rabbit urethral relaxation.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Canavanine; Cyclic GMP; Electric Stimulation; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rabbits; Urethra | 1994 |
Nitric oxide in retina: relation to excitatory amino acids and excitotoxicity.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Death; Chick Embryo; Cyclic GMP; gamma-Aminobutyric Acid; Glutamates; L-Lactate Dehydrogenase; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Retina | 1994 |
Glutamate receptors induce a burst of superoxide via activation of nitric oxide synthase in arginine-depleted neurons.
Topics: Amino Acid Oxidoreductases; Animals; Arginase; Arginine; Brain; Cell Death; Cells, Cultured; Cyclic GMP; Electron Spin Resonance Spectroscopy; Enzyme Activation; Male; Mice; N-Methylaspartate; Neurons; Nitric Oxide Synthase; Receptors, Glutamate; Superoxides | 1994 |
Depletion of intracellular Ca2+ stores activates nitric-oxide synthase to generate cGMP and regulate Ca2+ influx.
Topics: Amino Acid Oxidoreductases; Aminoquinolines; Animals; Arginine; Biological Transport; Calcium; Cyclic GMP; Enzyme Activation; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Pancreas; Rats; Signal Transduction | 1994 |
Cardiac preservation is enhanced in a heterotopic rat transplant model by supplementing the nitric oxide pathway.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Biosensing Techniques; Bradykinin; Coronary Vessels; Cyclic GMP; Endocardium; Graft Survival; Heart; Heart Transplantation; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroglycerin; Nitroprusside; Organ Preservation; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Transplantation, Heterotopic | 1994 |
Enhancement of cytosolic calcium, prostacyclin and nitric oxide by bradykinin and the ACE inhibitor ramiprilat in porcine brain capillary endothelial cells.
Topics: 1-Methyl-3-isobutylxanthine; 6-Ketoprostaglandin F1 alpha; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Bradykinin; Calcium; Capillaries; Cells, Cultured; Cerebrovascular Circulation; Cyclic GMP; Cytosol; Dose-Response Relationship, Drug; Endothelium, Vascular; Epoprostenol; Fura-2; Kinetics; Nitric Oxide; Nitroarginine; Ramipril; Swine | 1994 |
Inhibition of calcium-dependent nitric oxide synthase causes ileitis and leukocytosis in guinea pigs.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Citrulline; Cyclic GMP; Female; Guanidines; Guinea Pigs; Ileitis; Leukocyte Count; Leukocytosis; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peroxidase | 1994 |
Cyclic GMP in the perfused rat heart. Effect of ischaemia, anoxia and nitric oxide synthase inhibitor.
Topics: Adenosine Triphosphate; Amino Acid Oxidoreductases; Animals; Arginine; Coronary Circulation; Cyclic GMP; Fructosediphosphates; Glucose; Glycogen; Heart; Hexosephosphates; Hypoxia; In Vitro Techniques; Kinetics; Male; Myocardial Ischemia; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Perfusion; Rats; Rats, Wistar; Time Factors | 1994 |
Enhanced role of potassium channels in relaxations to acetylcholine in hypercholesterolemic rabbit carotid artery.
Topics: Acetylcholine; Analysis of Variance; Animals; Arginine; Carotid Arteries; Charybdotoxin; Cholesterol, Dietary; Cyclic GMP; Dose-Response Relationship, Drug; Hypercholesterolemia; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Potassium; Potassium Channels; Rabbits; Reference Values; Scorpion Venoms | 1994 |
Role of the endothelium and cyclic GMP in renal vasodilator responses to cryptolepine in rats.
Topics: Alkaloids; Animals; Antihypertensive Agents; Arginine; Cyclic GMP; Endothelium, Vascular; Hydroquinones; In Vitro Techniques; Indole Alkaloids; Indoles; Kidney; Male; Methylene Blue; Nitric Oxide; Nitroarginine; Potassium Chloride; Quinolines; Rats; Vasodilator Agents | 1994 |
Nitric oxide modulates endogenous dopamine release in bovine retina.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Basal Metabolism; Calcium; Cattle; Culture Media; Cyclic GMP; Dibutyryl Cyclic GMP; Dopamine; Feedback; Hydroxylamine; Hydroxylamines; In Vitro Techniques; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Retina | 1994 |
Mechanism underlying substance P-induced relaxation in dog isolated superficial temporal arteries.
Topics: Analysis of Variance; Animals; Arginine; Cyclic AMP; Cyclic GMP; Dogs; Electrophysiology; Endothelium, Vascular; Female; In Vitro Techniques; Indomethacin; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroarginine; Substance P; Temporal Arteries | 1994 |
Human osteoblast-like cells produce nitric oxide and express inducible nitric oxide synthase.
Topics: Amino Acid Oxidoreductases; Arginine; Base Sequence; Cells, Cultured; Cyclic GMP; Cytokines; Enzyme Induction; Humans; Molecular Probes; Molecular Sequence Data; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Osteoblasts; Polymerase Chain Reaction; Time Factors; Transcription, Genetic | 1994 |
Manganese potentiation of nitric oxide-mediated vascular relaxation.
Topics: Amino Acid Oxidoreductases; Animals; Aorta; Arginine; Blood Pressure; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Drug Interactions; In Vitro Techniques; Male; Manganese; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Sprague-Dawley | 1994 |
cGMP acts within cerebellar Purkinje cells to produce long term depression via mechanisms involving PKC and PKG.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Amino Acid Oxidoreductases; Animals; Arginine; Cyclic GMP; Electrophysiology; Enzyme Activation; Nitric Oxide Synthase; Nitroarginine; Potassium Chloride; Protein Kinase C; Purkinje Cells; Rats | 1994 |
Relaxation of rat thoracic aorta induced by the Ca(2+)-ATPase inhibitor, cyclopiazonic acid, possibly through nitric oxide formation.
Topics: Amino Acid Oxidoreductases; Animals; Anti-Arrhythmia Agents; Aorta, Thoracic; Arginine; Calcium; Calcium-Transporting ATPases; Calmodulin; Cyclic GMP; Enzyme Activation; In Vitro Techniques; Indoles; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Wistar; Stimulation, Chemical | 1994 |
Evidence that nitric oxide is an endogenous antiangiogenic mediator.
Topics: Allantois; Animals; Arginine; Chick Embryo; Chorion; Cyclic GMP; Dexamethasone; Drug Interactions; Endothelium, Vascular; Humans; Models, Biological; Neovascularization, Pathologic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Thrombin | 1994 |
Hypoxic coronary vasodilatation and cGMP overproduction are blocked by a nitric oxide synthase inhibitor, but not by a guanylyl cyclase ANF receptor antagonist.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Atrial Natriuretic Factor; Coronary Circulation; Cyclic GMP; Guanylate Cyclase; Guinea Pigs; Humans; Hypoxia; In Vitro Techniques; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Perfusion; Polysaccharides; Receptors, Atrial Natriuretic Factor; Vasodilation | 1994 |
Nitric oxide: a potent mediator of glutamatergic neurotoxicity in brain ischemia.
Topics: Amino Acid Oxidoreductases; Animals; Arachidonic Acid; Arginine; Brain; Brain Ischemia; Cyclic GMP; Gerbillinae; Glutamates; Male; Membrane Lipids; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 1994 |
Role of vascular nitric oxide synthase in endotoxin shock of Propionibacterium acnes-sensitized rats.
Topics: Amino Acid Oxidoreductases; Animals; Aorta; Arginine; Blood Pressure; Cyclic GMP; Dexamethasone; Enzyme Induction; Heart Rate; Hepatectomy; Hypersensitivity; Lipopolysaccharides; Male; Nitrates; Nitric Oxide Synthase; Nitrites; Nitroarginine; Propionibacterium acnes; Rats; Rats, Wistar; Shock, Septic; Splenectomy; Survival Analysis; Tissue Distribution | 1994 |
Induction of the nitric oxide-synthesizing pathway in fresh and interleukin 2-cultured rat natural killer cells.
Topics: Amino Acid Oxidoreductases; Animals; Antigens, Surface; Arginine; Cyclic GMP; Cytotoxicity Tests, Immunologic; Interleukin-2; Killer Cells, Lymphokine-Activated; Killer Cells, Natural; Lectins, C-Type; Nitric Oxide; Nitric Oxide Synthase; NK Cell Lectin-Like Receptor Subfamily B; Rats; Rats, Inbred F344; Tumor Cells, Cultured | 1994 |
Insulin increases guanosine-3',5'-cyclic monophosphate in human platelets. A mechanism involved in the insulin anti-aggregating effect.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Diphosphate; Adult; Amino Acid Oxidoreductases; Arginine; Blood Platelets; Collagen; Cyclic GMP; Female; Genistein; Guanylate Cyclase; Humans; Insulin; Isoflavones; Male; Methylene Blue; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein-Tyrosine Kinases; Radioimmunoassay; Recombinant Proteins | 1994 |
SIN-1 reverses attenuation of hypercapnic cerebrovasodilation by nitric oxide synthase inhibitors.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cerebrovascular Circulation; Cyclic GMP; Hypercapnia; Male; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Papaverine; Rats; Rats, Sprague-Dawley; Vasodilation | 1994 |
Dexamethasone inhibits the expression of an inducible nitric oxide synthase in infarcted rabbit myocardium.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Citrulline; Coronary Vessels; Cyclic GMP; Dexamethasone; Ligation; Male; Myocardial Infarction; Myocardium; Nitric Oxide Synthase; Rabbits | 1994 |
Constitutive expression of inducible nitric oxide synthase in human bronchial epithelial cells induces c-fos and stimulates the cGMP pathway.
Topics: Amino Acid Oxidoreductases; Animals; Antigens, Polyomavirus Transforming; Arginine; Base Sequence; Blotting, Northern; Bronchi; Carbon Radioisotopes; Cell Division; Cell Line, Transformed; Citrulline; Cyclic GMP; DNA Primers; Enzyme Induction; Epithelium; Gene Expression; Genes, fos; Humans; Kinetics; Mice; Molecular Sequence Data; Nitric Oxide Synthase; Polymerase Chain Reaction; Proto-Oncogene Proteins c-fos; Simian virus 40; Transfection | 1994 |
Localization and actions of nitric oxide in the cat carotid body.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Axons; Carotid Body; Cats; Cyclic GMP; Electrophysiology; Female; Immunohistochemistry; In Vitro Techniques; Lysine; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroglycerin | 1994 |
Hepatocyte inducible nitric oxide synthesis is influenced in vitro by cell density.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Biopterins; Cell Count; Cells, Cultured; Cyclic GMP; Cytokines; Humans; Lipopolysaccharides; Liver; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1994 |
The NO-cGMP pathway in neonatal rat dorsal horn.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Oxidoreductases; Animals; Animals, Newborn; Arginine; Biomarkers; Cyclic GMP; Female; Glutathione; Male; N-Methylaspartate; NADPH Dehydrogenase; Nerve Tissue Proteins; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Nitroso Compounds; Pain; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; S-Nitrosoglutathione; Second Messenger Systems; Signal Transduction; Spinal Cord | 1994 |
Pharmacologic differentiation between endothelium-dependent relaxations sensitive and resistant to nitro-L-arginine in coronary arteries.
Topics: Animals; Arginine; Biological Factors; Bradykinin; Bradykinin Receptor Antagonists; Cattle; Cells, Cultured; Coronary Vessels; Cyclic GMP; Endothelium, Vascular; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Quaternary Ammonium Compounds; Receptors, Bradykinin; Swine | 1994 |
Hippocampal in vitro kindling is not blocked by nitric oxide synthase inhibitors.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cyclic GMP; Electric Stimulation; Hippocampus; In Vitro Techniques; Kindling, Neurologic; Long-Term Potentiation; Male; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Synapses; Synaptic Transmission | 1994 |
Cyclic guanosine monophosphate is the mediator of platelet-activating factor inhibition on transport by the mouse kidney thick ascending limb.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Calcium; Chlorides; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Isoquinolines; Kidney Medulla; Kinetics; Loop of Henle; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Parathyroid Hormone; Platelet Activating Factor; Protein Kinase C; Time Factors; Vasopressins | 1994 |
IgE-dependent activation of Fc epsilon RII/CD23+ normal human keratinocytes: the role of cAMP and nitric oxide.
Topics: Amino Acid Oxidoreductases; Arginine; Bucladesine; Cyclic AMP; Cyclic GMP; Epidermal Cells; Humans; Immunoglobulin E; Interleukin-6; Keratinocytes; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Receptors, IgE; Signal Transduction; Thionucleotides; Tumor Necrosis Factor-alpha | 1994 |
Pineal nitric oxide synthase: characteristics, adrenergic regulation and function.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cyclic AMP; Cyclic GMP; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; omega-N-Methylarginine; Pineal Gland; Rats | 1994 |
Different pial arteriolar responses to acetylcholine in the newborn and juvenile pig.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Aging; Animals; Animals, Newborn; Arginine; Arterioles; Calcimycin; Cerebrovascular Circulation; Cyclic GMP; Female; Male; Nitroarginine; Nitroprusside; Pia Mater; Swine | 1994 |
Nitric oxide inhibits bafilomycin-sensitive H(+)-ATPase activity in rat cortical collecting duct.
Topics: Amino Acid Oxidoreductases; Animals; Anti-Bacterial Agents; Arginine; Cyclic GMP; Enzyme Induction; Ethylmaleimide; Female; In Vitro Techniques; Interferon-gamma; Kidney Tubules, Collecting; Kinetics; Lipopolysaccharides; Macrolides; Macrophages; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Proton-Translocating ATPases; Rats; Rats, Sprague-Dawley; Vacuoles | 1994 |
The intercellular communication via nitric oxide and its regulation in coupling of cyclic GMP synthesis upon stimulation of muscarinic cholinergic receptors in rat superior cervical sympathetic ganglia.
Topics: Acetylcholine; Amino Acid Oxidoreductases; Animals; Arginine; Axons; Carbachol; Cell Communication; Cholinergic Antagonists; Cyclic GMP; Denervation; Female; Hemoglobins; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Wistar; Receptors, Cholinergic; Superior Cervical Ganglion; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Trifluoperazine | 1994 |
Nitric oxide: an autocrine regulator of human granulosa-luteal cell steroidogenesis.
Topics: Amino Acid Oxidoreductases; Arginine; Aromatase; Base Sequence; Cells, Cultured; Corpus Luteum; Cyclic GMP; Dose-Response Relationship, Drug; Estradiol; Female; Fluorescence; Granulosa Cells; Humans; Immunohistochemistry; Molecular Sequence Data; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Polymerase Chain Reaction; Progesterone; RNA, Messenger | 1994 |
Nitric oxide mediates angiogenesis in vivo and endothelial cell growth and migration in vitro promoted by substance P.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Division; Cell Movement; Cells, Cultured; Cyclic GMP; DNA; Endothelium, Vascular; Neovascularization, Pathologic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Platelet Aggregation; Rabbits; Substance P | 1994 |
Presence of constitutive type nitric oxide synthase in cultured astrocytes isolated from rat cerebra.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Astrocytes; Brain; Cells, Cultured; Citrulline; Cyclic GMP; Histocytochemistry; NADPH Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats | 1994 |
Induction in the rat hippocampus of long-term potentiation (LTP) and long-term depression (LTD) in the presence of a nitric oxide synthase inhibitor.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cyclic GMP; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Long-Term Potentiation; N-Methylaspartate; Neuronal Plasticity; Neurons; Nitric Oxide Synthase; Nitroarginine; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Time Factors | 1994 |
In vitro endotoxin exposure induces contractile dysfunction in adult rat cardiac myocytes.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Cell Survival; Cells, Cultured; Citrulline; Cyclic GMP; Dactinomycin; Electric Stimulation; Endotoxins; Heart; Kinetics; Male; Myocardial Contraction; Myocardium; NG-Nitroarginine Methyl Ester; Nitroprusside; Rats; Rats, Sprague-Dawley; Time Factors | 1994 |
Nitric oxide synthase activity, viability and cyclic GMP levels in rat colonic epithelial cells: effect of endotoxin challenge.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Survival; Colon; Cyclic GMP; Enzyme Induction; Epithelium; Immune Sera; Lipopolysaccharides; Male; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar | 1994 |
Role of nitric oxide in glycerol-induced acute renal failure in rats.
Topics: Acute Kidney Injury; Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Cyclic GMP; Female; Glomerular Filtration Rate; Glycerol; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Sprague-Dawley; Renal Circulation | 1994 |
Insulin secretion in rats with chronic nitric oxide synthase blockade.
Topics: Amino Acid Oxidoreductases; Animals; Aorta, Thoracic; Arginine; Blood Glucose; Blood Pressure; Body Weight; Cyclic GMP; Epinephrine; Heart Rate; Insulin; Insulin Secretion; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Norepinephrine; Rats; Rats, Wistar; Reference Values; Time Factors | 1994 |
Attenuation of sodium nitroprusside responses after prolonged incubation of rat aorta with endotoxin.
Topics: Amino Acid Oxidoreductases; Animals; Aorta; Arginine; Cyclic GMP; Endothelium, Vascular; Endotoxins; Enzyme Activation; Escherichia coli; Guanylate Cyclase; Kinetics; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Papaverine; Rats; Rats, Wistar; Vasodilation | 1994 |
Role of nitric oxide in control of prolactin release by the adenohypophysis.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Atrial Natriuretic Factor; Cyclic GMP; Dibutyryl Cyclic GMP; Dopamine; Dose-Response Relationship, Drug; Guanylate Cyclase; Hemoglobins; In Vitro Techniques; Luteinizing Hormone; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Wistar; Substance P; Vasoactive Intestinal Peptide | 1995 |
The role of nitric oxide in the central control of blood pressure.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Calcium Chloride; Cerebral Ventricles; Cyclic GMP; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Inbred WKY; Thionucleotides | 1995 |
Muscarinic cholinergic stimulation of the nitric oxide-cyclic GMP signaling system in cultured rat sensory neurons.
Topics: Acetylcholine; Amino Acid Oxidoreductases; Animals; Arginine; Atropine; Capsaicin; Carbachol; Cells, Cultured; Cyclic GMP; Embryo, Mammalian; Ganglia, Spinal; Guanylate Cyclase; Methacholine Chloride; Methylene Blue; Neurons, Afferent; Nicotine; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Oxotremorine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Signal Transduction | 1994 |
Desulfated hirugen (hirudin 54-65) induces endothelium-dependent relaxation of porcine pulmonary arteries.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Sequence; Animals; Arginine; Atropine; Bradykinin; Calcium; Captopril; Cyclic GMP; Dinoprost; Endothelium, Vascular; Hirudins; Histamine; Indomethacin; Ketanserin; Methiothepin; Molecular Sequence Data; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Peptide Fragments; Phentolamine; Pulmonary Artery; Swine; Vasodilation | 1994 |
Opioids and nitric oxide contribute to hypoxia-induced pial arterial vasodilation in newborn pigs.
Topics: Amino Acid Oxidoreductases; Analysis of Variance; Animals; Animals, Newborn; Arginine; Arterioles; Cerebral Arteries; Cyclic GMP; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Enkephalins; Female; Hypoxia; Male; Muscle, Smooth, Vascular; Naltrexone; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Receptors, Opioid, kappa; Receptors, Opioid, mu; Swine; Vasodilation | 1995 |
Renal hemodynamic effects of dietary protein in the rat: role of nitric oxide.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cyclic GMP; Dietary Proteins; Glomerular Filtration Rate; Hemodynamics; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Sprague-Dawley; Vascular Resistance; Vasodilation | 1995 |
Inhibition of neuronal nitric oxide synthase by antipsychotic drugs.
Topics: Amino Acid Oxidoreductases; Animals; Antipsychotic Agents; Arginine; Brain Neoplasms; Calmodulin; Cerebellum; Citrulline; Cyclic GMP; Cytosol; In Vitro Techniques; Male; Mice; Neuroblastoma; Neurons; Nitric Oxide Synthase; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Tumor Cells, Cultured | 1994 |
Nitric oxide synthase inhibitor alters papillary muscle force-frequency relationship.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Calcium Channels; Cricetinae; Cyclic GMP; Electric Stimulation; In Vitro Techniques; Male; Mesocricetus; Myocardial Contraction; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Papillary Muscles | 1995 |
Essential role for nitric oxide in neurogenic inflammation in rat cutaneous microcirculation. Evidence for an endothelium-independent mechanism.
Topics: Animals; Arginine; Blood Pressure; Cyclic GMP; Endothelium, Vascular; Indazoles; Inflammation; Male; Microcirculation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Regional Blood Flow; Skin; Substance P | 1995 |
Tyrosine kinase inhibitors enhance cGMP production in rat pinealocytes.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Oxidoreductases; Animals; Arginine; Catechols; Cyclic AMP; Cyclic GMP; Genistein; Hydroquinones; Isoflavones; Isoproterenol; Male; Nitric Oxide Synthase; Nitriles; Norepinephrine; omega-N-Methylarginine; Pineal Gland; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Tyrphostins | 1995 |
The role of nitric oxide in the transformation of visual information within the dorsal lateral geniculate nucleus of the cat.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cats; Cyclic GMP; Geniculate Bodies; Iontophoresis; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Receptors, N-Methyl-D-Aspartate; Vision, Ocular | 1994 |
No mimics O2 in the carotid body chemoreception.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Carotid Body; Cats; Chemoreceptor Cells; Cyclic GMP; In Vitro Techniques; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Oxygen | 1994 |
Influence of nitric oxide synthase inhibition, nitric oxide and hydroperoxide on insulin release induced by various secretagogues.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Oxidoreductases; Animals; Arginine; Colforsin; Cyclic AMP; Cyclic GMP; Female; Glucose; Hydrogen Peroxide; Hydroxylamine; Hydroxylamines; In Vitro Techniques; Insulin; Islets of Langerhans; Mice; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peroxides; Reactive Oxygen Species; tert-Butylhydroperoxide; Vasodilator Agents | 1995 |
Inducible nitric oxide synthase in rat hepatic lipocytes and the effect of nitric oxide on lipocyte contractility.
Topics: Adipocytes; Amino Acid Oxidoreductases; Animals; Arginine; Base Sequence; Cell Movement; Cells, Cultured; Common Bile Duct; Cyclic GMP; Cytokines; Enzyme Induction; Liver; Male; Molecular Sequence Data; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1995 |
The role of free radicals in NMDA-dependent neurotoxicity.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Calcium; Cells, Cultured; Cerebellar Cortex; Cyclic GMP; Electron Spin Resonance Spectroscopy; Enzyme Activation; Epilepsy; Feedback; Free Radicals; Glutamic Acid; Guanylate Cyclase; Kindling, Neurologic; Mice; Molsidomine; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rats; Receptors, N-Methyl-D-Aspartate | 1994 |
Characterization of neuronal amino acid transporters: uptake of nitric oxide synthase inhibitors and implication for their biological effects.
Topics: Amino Acid Oxidoreductases; Amino Acid Transport Systems; Amino Acids; Animals; Arginine; Biological Transport; Carrier Proteins; Cyclic GMP; Mice; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Tumor Cells, Cultured | 1995 |
Nitric oxide synthesis in rat mesangial cells induced by cytokines.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Oxidoreductases; Animals; Arginine; Cells, Cultured; Chemotactic Factors; Cyclic GMP; Cycloheximide; Cytokines; Dactinomycin; Dexamethasone; Dose-Response Relationship, Drug; Gene Expression; Glomerular Mesangium; Interleukin-1; Interleukin-6; Interleukin-8; Kinetics; Male; Monocyte Chemoattractant Proteins; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Transcription, Genetic; Transforming Growth Factor beta | 1994 |
In vivo treatment with endotoxin induces nitric oxide synthase in rat main pulmonary artery.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Base Sequence; Cyclic GMP; Dexamethasone; Endothelium, Vascular; Guanidines; Lipopolysaccharides; Male; Molecular Sequence Data; Muscle Contraction; Nitric Oxide Synthase; omega-N-Methylarginine; Phenylephrine; Phosphatidylethanolamines; Potassium Chloride; Pulmonary Artery; Rats; Rats, Wistar; RNA, Messenger | 1995 |
Role of nitric oxide and cAMP in beta-adrenoceptor-induced pial artery vasodilation.
Topics: Albuterol; Amino Acid Oxidoreductases; Animals; Animals, Newborn; Arginine; Colforsin; Cyclic AMP; Cyclic GMP; Dobutamine; Enzyme Activation; Female; Isoproterenol; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Pia Mater; Receptors, Adrenergic, beta; Swine; Vasodilation | 1995 |
Nitric oxide responses of air-breathing and water-breathing fish.
Topics: Acetylcholine; Air; Air Sacs; Amino Acid Oxidoreductases; Animals; Arginine; Biological Evolution; Cyclic GMP; Fishes; In Vitro Techniques; Lung; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Oncorhynchus mykiss; Respiration; Species Specificity; Water | 1995 |
Nitric oxide modulation of agonist-evoked intracellular Ca2+ release in neurosecretory PC-12 cells: inhibition of phospholipase C activity via cyclic GMP-dependent protein kinase I.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Calcium; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Activation; Inositol 1,4,5-Trisphosphate; Intracellular Fluid; Neurosecretory Systems; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; PC12 Cells; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Rats; Receptors, Cell Surface; Signal Transduction; Type C Phospholipases | 1995 |
Hypercapnic vasodilatation in isolated rat basilar arteries is exerted via low pH and does not involve nitric oxide synthase stimulation or cyclic GMP production.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Basilar Artery; Cyclic GMP; Hydrogen-Ion Concentration; Hypercapnia; Male; Methylene Blue; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Wistar; Tetrodotoxin; Vasodilation | 1994 |
Ramipril prevents the detrimental sequels of chronic NO synthase inhibition in rats: hypertension, cardiac hypertrophy and renal insufficiency.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Cardiomegaly; Cyclic GMP; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Ramipril; Rats; Rats, Wistar; Renal Insufficiency; Ventricular Fibrillation | 1994 |
Natriuretic peptide-augmented induction of nitric oxide synthase through cyclic guanosine 3',5'-monophosphate elevation in vascular smooth muscle cells.
Topics: Amino Acid Oxidoreductases; Animals; Antihypertensive Agents; Aorta; Arginine; Atrial Natriuretic Factor; Cells, Cultured; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Induction; Humans; Interleukin-1; Kinetics; Muscle, Smooth, Vascular; Natriuretic Peptide, C-Type; Nerve Tissue Proteins; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Proteins; Rats; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1995 |
Cyclic nucleotides and vasoactive intestinal peptide production in a rabbit model of Escherichia coli septicemia.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Bacteremia; Blood Pressure; Cyclic AMP; Cyclic GMP; Disease Models, Animal; Escherichia coli Infections; Heart Rate; Lactates; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rabbits; Reference Values; Vasoactive Intestinal Peptide | 1995 |
Autocrine inhibition of Na+/K(+)-ATPase by nitric oxide in mouse proximal tubule epithelial cells.
Topics: Amino Acid Oxidoreductases; Analysis of Variance; Animals; Arginine; Cells, Cultured; Cyclic GMP; Enzyme Induction; Epithelium; Interferon-gamma; Kidney Tubules, Proximal; Kinetics; Lipopolysaccharides; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nystatin; Sodium-Potassium-Exchanging ATPase; Superoxide Dismutase; Thionucleotides | 1995 |
Nitric oxide modulation of quantal secretion in chick ciliary ganglia.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Action Potentials; Amino Acid Oxidoreductases; Animals; Arginine; Chickens; Cyclic GMP; Electric Stimulation; Evoked Potentials; Ganglia, Parasympathetic; In Vitro Techniques; Long-Term Potentiation; Microelectrodes; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Oculomotor Nerve; Synapses; Synaptic Transmission | 1994 |
Role of cyclic nucleotides and nitric oxide in blood mononuclear cell IgE production stimulated by IL-4.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Arginine; B-Lymphocytes; Cholera Toxin; Cyclic AMP; Cyclic GMP; Drug Synergism; Epinephrine; Gene Expression Regulation; Humans; Immunoglobulin E; Interleukin-4; Leukocytes, Mononuclear; Molsidomine; Nitric Oxide; omega-N-Methylarginine; Receptors, IgE; Recombinant Fusion Proteins | 1995 |
Interleukin-1 beta induces the formation of nitric oxide in isolated juxtaglomerular cells: influence on renin secretion.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cells, Cultured; Cyclic GMP; Enzyme Induction; Female; Interleukin-1; Juxtaglomerular Apparatus; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Oxyhemoglobins; Renin | 1995 |
Further characterization and comparison of inducible nitric oxide synthase in mouse, rat, and human hepatocytes.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Oxidoreductases; Animals; Arginine; Cells, Cultured; Cyclic GMP; Dexamethasone; Enzyme Induction; Gene Expression; Humans; Interferon-gamma; Interleukin-1; Interleukins; Isoenzymes; Lipopolysaccharides; Liver; Mice; Nitrates; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Rats; Recombinant Proteins; RNA, Messenger; Species Specificity; Tumor Necrosis Factor-alpha | 1995 |
Nitric oxide modulates agonist-evoked Ca2+ release and influx responses in PC12-64 cells.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Calcium; Cyclic GMP; Homeostasis; Muscarinic Agonists; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; PC12 Cells; Rats; Receptors, Muscarinic; Signal Transduction | 1995 |
Met-enkephalin receptor-mediated increase of membrane fluidity modulates nitric oxide (NO) and cGMP production in rat brain synaptosomes.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cerebral Cortex; Cyclic GMP; Enkephalin, Methionine; Fluorescence Polarization; Kinetics; Membrane Fluidity; Naloxone; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Receptors, Opioid; Synaptosomes; Thermodynamics | 1995 |
Interleukin-1 beta suppresses apoptosis in rat ovarian follicles by increasing nitric oxide production.
Topics: Amino Acid Oxidoreductases; Animals; Apoptosis; Arginine; Chorionic Gonadotropin; Culture Techniques; Cyclic AMP; Cyclic GMP; DNA; Female; Gonadotropins, Equine; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Ovarian Follicle; Rats; Rats, Sprague-Dawley; Sialoglycoproteins | 1995 |
Activation of CFTR chloride current by nitric oxide in human T lymphocytes.
Topics: Aminoquinolines; Arginine; CD4-Positive T-Lymphocytes; Chloride Channels; Clone Cells; Cyclic GMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Guanylate Cyclase; Humans; Membrane Proteins; Nitric Oxide; Patch-Clamp Techniques; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Signal Transduction | 1995 |
Acute blockade of nitric oxide synthase inhibits renal vasodilation and hyperfiltration during pregnancy in chronically instrumented conscious rats.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cyclic GMP; Female; Glomerular Filtration Rate; Kidney; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Pregnancy; Pregnancy, Animal; Rats; Renal Circulation; Vasodilation | 1995 |
The nitric oxide transduction pathway in Trypanosoma cruzi.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Citrulline; Cyclic GMP; Dizocilpine Maleate; Guanylate Cyclase; Nitric Oxide; Nitric Oxide Synthase; Receptors, N-Methyl-D-Aspartate; Trypanosoma cruzi | 1995 |
Cerebrovascular alterations in mice lacking neuronal nitric oxide synthase gene expression.
Topics: Acetylcholine; Amino Acid Oxidoreductases; Animals; Arginine; Brain; Carbon Dioxide; Cerebrovascular Circulation; Cyclic GMP; Endothelium, Vascular; Immunohistochemistry; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; Regional Blood Flow; Skull; Tissue Distribution; Vasoconstriction; Vasodilation | 1995 |
Determination of brain nitric oxide synthase inhibition in vivo: ex vivo assays of nitric oxide synthase can give incorrect results.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Brain; Cerebellum; Cyclic GMP; Harmaline; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Ornithine; Rats; Rats, Wistar | 1995 |
Enhanced nitric oxide synthase activity in portal hypertensive rabbits.
Topics: Amino Acid Oxidoreductases; Animals; Aorta, Thoracic; Arginine; Calcium; Cyclic GMP; Endothelium, Vascular; Hemodynamics; Hypertension, Portal; Ligation; Male; Mesenteric Artery, Superior; NADPH Dehydrogenase; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Portal Vein; Rabbits | 1995 |
A possible role for nitric oxide in modulating the functional cyclosporine toxicity by arginine.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Creatinine; Cyclic GMP; Cyclosporine; Hemodynamics; Isoenzymes; Kidney; Male; Nitric Oxide; Nitric Oxide Synthase; Proteinuria; Rats; Rats, Inbred Lew; Renal Circulation; RNA, Messenger | 1995 |
Leukocyte adhesion induced by inhibition of nitric oxide production in skeletal muscle.
Topics: Amino Acid Oxidoreductases; Animals; Antibodies, Monoclonal; Arginine; Blood Flow Velocity; Cell Adhesion; Cyclic GMP; Endothelium, Vascular; Kinetics; Leukocytes; Male; Microcirculation; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Rats; Rats, Sprague-Dawley; Splanchnic Circulation; Superoxide Dismutase | 1995 |
Erythrocyte stages of Plasmodium falciparum exhibit a high nitric oxide synthase (NOS) activity and release an NOS-inducing soluble factor.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Biological Factors; Canavanine; Cell Adhesion; Cells, Cultured; Citrulline; Culture Media, Conditioned; Cyclic GMP; Endothelium, Vascular; Enzyme Induction; Erythrocytes; Host-Parasite Interactions; Humans; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Plasmodium; Plasmodium falciparum; Protozoan Proteins; Species Specificity; Umbilical Veins | 1995 |
Possible regulation of capacitative Ca2+ entry into colonic epithelial cells by NO and cGMP.
Topics: Amino Acid Oxidoreductases; Aminoquinolines; Arginine; Barium; Biological Transport; Calcium; Carbachol; Colon; Colonic Neoplasms; Cyclic GMP; Epithelium; Guanylate Cyclase; Humans; Indoles; Intestinal Mucosa; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Second Messenger Systems; Tumor Cells, Cultured | 1995 |
Protection against ischemic injury by nonvasoactive concentrations of nitric oxide synthase inhibitors in the perfused rabbit heart.
Topics: Adenosine Triphosphate; Amino Acid Oxidoreductases; Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glucose; Glycolysis; Magnetic Resonance Spectroscopy; Male; Myocardial Reperfusion Injury; Myocardium; NADPH Dehydrogenase; Nitric Oxide Synthase; omega-N-Methylarginine; Perfusion; Phosphocreatine; Rabbits; Time Factors | 1995 |
Endothelium-dependent vasorelaxant effect of trilinolein: mediated by nitric oxide and cyclic GMP.
Topics: Amino Acid Oxidoreductases; Analysis of Variance; Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Triglycerides; Vasodilation | 1995 |
Nitric oxide modulates pepsinogen secretion induced by calcium-mediated agonist in guinea pig gastric chief cells.
Topics: Animals; Arginine; Calcium; Calmodulin; Carbachol; Cells, Cultured; Cholecystokinin; Citrulline; Cyclic GMP; Egtazic Acid; Gastric Mucosa; Gastrins; Guinea Pigs; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Pepsinogens; Terpenes; Thapsigargin | 1995 |
Normalization of nitric oxide production corrects arterial vasodilation and hyperdynamic circulation in cirrhotic rats.
Topics: Animals; Arginine; Arteries; Blood Pressure; Cyclic GMP; Hemodynamics; Liver Cirrhosis, Experimental; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Renin; Vascular Resistance; Vasodilation; Vasopressins | 1995 |
Endothelium-dependent vasorelaxation caused by various plant extracts.
Topics: Animals; Aorta; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Fruit; In Vitro Techniques; Magnoliopsida; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nuts; omega-N-Methylarginine; Phenylephrine; Plant Extracts; Radioimmunoassay; Rats; Spices; Tea; Vasoconstrictor Agents; Vegetables | 1995 |
[A study on hypotensive mechanism of adrenomedullin (13-52)].
Topics: Adrenomedullin; Animals; Antihypertensive Agents; Aorta, Thoracic; Arginine; Blood Pressure; Cyclic GMP; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroarginine; Peptides; Rats; Rats, Wistar | 1995 |
Chronic treatment with nitric oxide synthase (NOS) inhibitor profoundly reduces cerebellar NOS activity and cyclic guanosine monophosphate but does not modify minimum alveolar anesthetic concentration.
Topics: Animals; Arginine; Cerebellum; Cyclic GMP; Enzyme Inhibitors; Halothane; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley | 1995 |
Activation of NO:cGMP pathway by acetylcholine in bovine chromaffin cells. Possible role of Ca2+ in the down-regulation of cGMP signaling.
Topics: Acetylcholine; Adrenal Medulla; Animals; Arginine; Calcium; Cattle; Cyclic GMP; Down-Regulation; Ionomycin; Natriuretic Peptide, C-Type; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Proteins; Signal Transduction | 1995 |
NANC neurotransmission in lamina propria of the rabbit urethra: regulation by different subsets of calcium channels.
Topics: Animals; Arginine; Calcium; Calcium Channels; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Electric Stimulation; Electrophysiology; Enzyme Inhibitors; Female; Nitroarginine; Rabbits; Urethra | 1995 |
Endothelium-dependent relaxation to acetylcholine in bovine oviductal arteries: mediation by nitric oxide and changes in apamin-sensitive K+ conductance.
Topics: Acetylcholine; Animals; Apamin; Arginine; Arteries; Cattle; Cyclic GMP; Cysteine; Endothelium, Vascular; Enzyme Inhibitors; Fallopian Tubes; Female; In Vitro Techniques; Methylene Blue; Muscle Relaxation; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Ouabain; Potassium; Potassium Channel Blockers; S-Nitrosothiols | 1995 |
Differential significance of nitric oxide in hypotensive mechanisms of acetylcholine and histamine in dogs.
Topics: Acetylcholine; Animals; Arginine; Blood Pressure; Cyclic GMP; Dogs; Endothelium, Vascular; Female; Histamine; Male; Nitric Oxide; Nitroarginine | 1995 |
Relaxin activates the L-arginine-nitric oxide pathway in human breast cancer cells.
Topics: Arginine; Breast Neoplasms; Cyclic GMP; Female; Humans; Nitric Oxide; Nitric Oxide Synthase; Relaxin; Thymidine; Tumor Cells, Cultured | 1995 |
Angiotensin-II-induced increase in transcoronary protein clearance: role of hypertension vs. nitric oxide or cyclo-oxygenase products.
Topics: Angiotensin II; Animals; Arginine; Arteries; Blood Pressure; Coronary Vessels; Cyclic GMP; Cyclooxygenase Inhibitors; Dinoprostone; Dogs; Indomethacin; Lymph; Male; Metabolic Clearance Rate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Proteins; Vasoconstrictor Agents | 1995 |
L-NMMA blocks carbachol-induced increases in cGMP levels but not decreases in tension in the presence of forskolin in rabbit papillary muscles.
Topics: Animals; Arginine; Carbachol; Colforsin; Cyclic GMP; Female; Guanylate Cyclase; In Vitro Techniques; Male; Muscarinic Agonists; Myocardial Contraction; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Papillary Muscles; Rabbits | 1995 |
Chronic angiotensin-converting enzyme inhibition and endothelial function of rat aorta.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Arginine; Bradykinin; Cyclic GMP; Drug Synergism; Endothelium, Vascular; Hydralazine; Male; Nitric Oxide; omega-N-Methylarginine; Peptidyl-Dipeptidase A; Ramipril; Rats; Rats, Wistar; Vasodilation | 1995 |
Platelet rap1B phosphorylation is a sensitive marker for the action of cyclic AMP- and cyclic GMP-increasing platelet inhibitors and vasodilators.
Topics: Arginine; Autoradiography; Biomarkers; Blood Platelets; Blood Protein Electrophoresis; Blotting, Western; Cells, Cultured; Cyclic AMP; Cyclic GMP; Epoprostenol; GTP-Binding Proteins; Humans; In Vitro Techniques; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Phosphorylation; Platelet Aggregation Inhibitors; rap GTP-Binding Proteins; Signal Transduction; Vasodilator Agents | 1995 |
Role of nitric oxide in restitution of injured guinea pig gastric mucosa in vitro.
Topics: Animals; Arginine; Bicarbonates; Cyclic GMP; Dibutyryl Cyclic GMP; Gastric Mucosa; Guinea Pigs; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Mannitol; Methylene Blue; Microscopy, Electron; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Saline Solution, Hypertonic; Stereoisomerism; Time Factors | 1995 |
Role of nitric oxide in regulation of vascular resistance in postnatal intestine.
Topics: Aging; Analysis of Variance; Animals; Animals, Newborn; Arginine; Blood Pressure; Cyclic GMP; Endothelium, Vascular; In Vitro Techniques; Infusions, Intra-Arterial; Intestines; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Oxygen; Partial Pressure; Potassium Chloride; Regional Blood Flow; Swine; Vascular Resistance | 1995 |
Glomerular and tubular interactions between renal adrenergic activity and nitric oxide.
Topics: Analysis of Variance; Angiotensin II; Animals; Arginine; Capillaries; Cyclic GMP; Denervation; Glomerular Filtration Rate; Kidney; Kidney Glomerulus; Kidney Tubules; Male; Models, Biological; Models, Theoretical; Nephrons; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Wistar; Renal Circulation | 1995 |
Nitric oxide/cyclic guanosine monophosphate system in the spinal cord differentially modulates intracerebroventricularly administered morphine- and beta-endorphin-induced antinociception in the mouse.
Topics: Analgesics; Animals; Arginine; beta-Endorphin; Cyclic GMP; Dose-Response Relationship, Drug; Hemoglobins; Injections, Intraventricular; Injections, Spinal; Male; Methylene Blue; Mice; Mice, Inbred ICR; Morphine; Nitric Oxide; Oligopeptides; Spinal Cord | 1995 |
Complex involvement of nitric oxide and cGMP at N-methyl-D-aspartic acid receptors regulating gamma-[3H]aminobutyric acid release from striatal slices.
Topics: Aminobutyrates; Animals; Arginine; Corpus Striatum; Cyclic GMP; gamma-Aminobutyric Acid; Male; Nitric Oxide; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Time Factors | 1995 |
Evidence for the involvement of cGMP in neural bronchodilator responses in humal trachea.
Topics: Adenosine Monophosphate; Adolescent; Adult; Arginine; Bronchoconstriction; Child; Chymotrypsin; Cyclic GMP; Electric Conductivity; Epithelium; Female; Humans; Male; Methylene Blue; Middle Aged; Molsidomine; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Tetrodotoxin; Time Factors; Trachea; Vasoactive Intestinal Peptide; Vasodilator Agents | 1995 |
Potentiation of the hyporeactivity induced by in vivo endothelial injury in the rat carotid artery by chronic treatment with fish oil.
Topics: Analysis of Variance; Animals; Arginine; Blood Pressure; Body Weight; Carotid Arteries; Carotid Artery Injuries; Catheterization; Cyclic GMP; Endothelium, Vascular; Fatty Acids; Fish Oils; Indomethacin; Isometric Contraction; Male; Methylene Blue; Molsidomine; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Phenylephrine; Rats; Rats, Wistar; Superoxide Dismutase; Vascular Resistance; Vasodilator Agents | 1995 |
Control of cardiac muscle cell function by an endogenous nitric oxide signaling system.
Topics: Aging; Amino Acid Oxidoreductases; Animals; Animals, Newborn; Arginine; Carbachol; Cells, Cultured; Cyclic GMP; Heart; Heart Rate; Heart Ventricles; Isoproterenol; Methylene Blue; Myocardial Contraction; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Oxyhemoglobins; Rats; Signal Transduction | 1993 |
Nitric oxide synthase in the autonomic nervous system of canine ileum.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Autonomic Nervous System; Calcium; Citrulline; Cyclic GMP; Dogs; Guanylate Cyclase; Ileum; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Neuromuscular Junction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Subcellular Fractions; Synaptosomes; Tritium | 1993 |
Ca2+/calmodulin-dependent nitric oxide synthase activity in the human cervix carcinoma cell line ME-180.
Topics: Amino Acid Oxidoreductases; Arginine; Calcium; Calmodulin; Cyclic GMP; Female; Humans; Interferon-gamma; Kinetics; Lipopolysaccharides; Nitric Oxide Synthase; omega-N-Methylarginine; Pteridines; Recombinant Proteins; Tumor Cells, Cultured; Uterine Cervical Neoplasms | 1993 |
Induction of nitric oxide synthase regulates atrial natriuretic peptide receptors in vascular smooth muscle cells.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Atrial Natriuretic Factor; Autoradiography; Cells, Cultured; Cross-Linking Reagents; Cyclic GMP; Enzyme Induction; In Vitro Techniques; Interleukin-1; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitrites; Nitroarginine; Nitroprusside; Peptide Fragments; Rabbits; Receptors, Atrial Natriuretic Factor | 1993 |
Cytotoxicity of activated rat macrophages against syngeneic islet cells is arginine-dependent, correlates with citrulline and nitrite concentrations and is identical to lysis by the nitric oxide donor nitroprusside.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Cells, Cultured; Citrulline; Cyclic GMP; Female; Islets of Langerhans; Kinetics; Macrophage Activation; Macrophages; Male; Nitric Oxide; Nitrites; Nitroprusside; omega-N-Methylarginine; Rats; Rats, Wistar; Thionucleotides | 1993 |
Interleukin-1 beta effects on cyclic GMP and cyclic AMP in cultured rat islets of Langerhans-arginine-dependence and relationship to insulin secretion.
Topics: 1-Methyl-3-isobutylxanthine; Aminoquinolines; Animals; Antihypertensive Agents; Arginine; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Female; Insulin; Insulin Secretion; Interleukin-1; Islets of Langerhans; Kinetics; Molsidomine; NG-Nitroarginine Methyl Ester; Rats; Rats, Sprague-Dawley | 1993 |
Phorbol esters induce nitric oxide synthase and increase arginine influx in cultured peritoneal macrophages.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cells, Cultured; Cyclic GMP; Enzyme Activation; Enzyme Induction; Lipopolysaccharides; Macrophages; Male; Nitric Oxide; Nitric Oxide Synthase; Peritoneal Cavity; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats | 1993 |
Selective inhibition of the inducible nitric oxide synthase by aminoguanidine.
Topics: Amino Acid Oxidoreductases; Animals; Aorta, Thoracic; Arginine; Cells, Cultured; Citrulline; Cyclic GMP; Guanidines; Macrophages; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Sprague-Dawley; Spectrometry, Fluorescence | 1993 |
Identification of increased nitric oxide biosynthesis during pregnancy in rats.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cyclic GMP; Diet; Female; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Pregnancy; Pregnancy, Animal; Rats | 1993 |
Endothelin receptor subtype B mediates synthesis of nitric oxide by cultured bovine endothelial cells.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blotting, Northern; Calcium; Calmodulin; Cattle; Cyclic GMP; Endothelins; Endothelium, Vascular; Enzyme Activation; GTP-Binding Proteins; Inosine Triphosphate; Iodine Radioisotopes; Nitrates; Nitric Oxide Synthase; Nitrites; Peptide Fragments; Pertussis Toxin; Receptors, Endothelin; Virulence Factors, Bordetella | 1993 |
IL1 and TNF alpha induce cGMP formation in C6 astrocytoma cells via the nitridergic pathway.
Topics: 1-Methyl-3-isobutylxanthine; Arginine; Astrocytoma; Cyclic GMP; Interleukin-1; Nitrites; omega-N-Methylarginine; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1993 |
Nitric oxide synthase: involvement of oxygen radicals in conversion of L-arginine to nitric oxide.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Brain; Catalase; Cyclic GMP; Enzyme Activation; Guanylate Cyclase; In Vitro Techniques; NADP; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxide Dismutase | 1993 |
Vasoactive intestinal peptide stimulation of cyclic guanosine monophosphate formation: further evidence for a role of nitric oxide synthase and cytosolic guanylate cyclase in rat pinealocytes.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cyclic GMP; Cytosol; Drug Synergism; Guanylate Cyclase; Methylene Blue; Nitric Oxide Synthase; omega-N-Methylarginine; Phenylephrine; Pineal Gland; Rats; Vasoactive Intestinal Peptide | 1993 |
Inhibition of nitric oxide production. Mechanisms of vascular albumin leakage.
Topics: Albumins; Animals; Arginine; Azepines; Blood Flow Velocity; Cell Adhesion; Cell Adhesion Molecules; Cell Movement; Cyclic GMP; Intercellular Adhesion Molecule-1; Leukocytes; Male; NG-Nitroarginine Methyl Ester; P-Selectin; Phalloidine; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Sprague-Dawley; Triazoles; Venules | 1993 |
Cyclic GMP formation induced by muscarinic receptors is mediated by nitric oxide synthesis in rat cortical primary cultures.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cells, Cultured; Cerebral Cortex; Cyclic GMP; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic | 1993 |
What are the types and cellular sources of free radicals in the pathogenesis of type 1 (insulin-dependent) diabetes mellitus?
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cyclic GMP; Diabetes Mellitus, Type 1; Free Radicals; Humans; Insulinoma; Interferon-gamma; Interleukin-1; Islets of Langerhans; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Pancreatic Neoplasms; Rats; Tumor Cells, Cultured | 1993 |
Nitric oxide-generating system as an autocrine mechanism in human polymorphonuclear leucocytes.
Topics: 1-Methyl-3-isobutylxanthine; Arginine; Biological Transport; Citrulline; Cyclic GMP; Endothelins; Humans; In Vitro Techniques; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitric Oxide; Nitroprusside; omega-N-Methylarginine | 1993 |
Glutamate receptor-induced cyclic GMP formation in primary cultures of mesencephalic neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Oxidoreductases; Animals; Arginine; Carbachol; Cells, Cultured; Cyclic GMP; Fetus; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Kinetics; Mesencephalon; Mice; N-Methylaspartate; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Phorbol 12,13-Dibutyrate; Quinoxalines; Receptors, Glutamate | 1993 |
Nitric oxide activates cyclooxygenase enzymes.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Line; Cyclic GMP; Dinoprostone; Enzyme Activation; Guanidines; Humans; Indomethacin; Mice; Nitrates; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Prostaglandin-Endoperoxide Synthases; Recombinant Proteins | 1993 |
Increase in nitric oxide and cyclic GMP of rat cerebellum by radio frequency burst-type electromagnetic field radiation.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cerebellum; Culture Techniques; Cyclic GMP; Electromagnetic Fields; Guanylate Cyclase; Male; NADP; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Vasodilation; Xenopus laevis | 1993 |
Prevention of nitric oxide synthase induction in vascular smooth muscle cells by microtubule depolymerizing agents.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Colchicine; Cyclic GMP; Cytoskeleton; Enzyme Induction; In Vitro Techniques; Interleukin-1; Lipopolysaccharides; Microtubules; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitroprusside; Nocodazole; omega-N-Methylarginine; Rats; Rats, Wistar | 1993 |
Systemic administration of lithium chloride and tacrine increases nitric oxide synthase activity in the hippocampus of rats.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Atropine; Cerebral Cortex; Chlorides; Cyclic GMP; Hippocampus; Lithium; Lithium Chloride; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; Seizures; Tacrine | 1993 |
Characterization of endothelial cell amino acid transport systems involved in the actions of nitric oxide synthase inhibitors.
Topics: Amino Acid Oxidoreductases; Amino Acids; Animals; Arginine; Biological Transport; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Leucine; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Swine | 1993 |
Reduction of nitric oxide producing activity associated with in vitro aging in cultured human umbilical vein endothelial cell.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Oxidoreductases; Animals; Arginine; Cell Division; Cell Line; Cells, Cultured; Cellular Senescence; Cerebellum; Cyclic GMP; Endothelium, Vascular; Epithelium; Humans; Kidney; Kinetics; Mice; Mice, Inbred Strains; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Tumor Cells, Cultured; Umbilical Veins | 1993 |
Chronic inhibition of nitric oxide production augments skin vasoconstriction in the rabbit ear.
Topics: Acetylcholine; Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Body Temperature; Cyclic GMP; Ear, External; In Vitro Techniques; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Rabbits; Regional Blood Flow; Skin; Vasoconstriction | 1993 |
Nitric oxide mediates IL-1 beta-induced islet dysfunction and destruction: prevention by dexamethasone.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cyclic GMP; Dexamethasone; Guanidines; Insulin; Insulin Secretion; Interleukin-1; Islets of Langerhans; Male; NADPH Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley | 1993 |
Involvement of nitric oxide in the endothelium-dependent relaxation induced by hydrogen peroxide in the rabbit aorta.
Topics: Amino Acid Oxidoreductases; Animals; Aorta, Thoracic; Arginine; Cyclic GMP; Endothelium, Vascular; Female; Hydrogen Peroxide; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rabbits | 1993 |
Activation of adrenal medullary L-arginine: nitric oxide pathway by stimuli which induce the release of catecholamines.
Topics: Adrenal Medulla; Amino Acid Oxidoreductases; Animals; Arginine; Catecholamines; Cats; Cattle; Cyclic GMP; Cytosol; Electric Stimulation; Nitric Oxide; Nitric Oxide Synthase | 1993 |
Inhibitors of nitric oxide synthase attenuate human neutrophil chemotaxis in vitro.
Topics: Amino Acid Oxidoreductases; Arginine; Canavanine; Chemotaxis, Leukocyte; Complement C5a, des-Arginine; Cyclic GMP; Humans; In Vitro Techniques; Kinetics; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Stereoisomerism | 1993 |
Stretch revealed three components in the hyperpolarization of guinea-pig coronary artery in response to acetylcholine.
Topics: Acetylcholine; Animals; Arginine; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Epoprostenol; Female; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Mechanoreceptors; Membrane Potentials; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandins; Rabbits; Rats; Sheep; Substance P | 1993 |
Antagonism by NG-nitro-L-arginine of L-glutamate-induced neurotoxicity in cultured neonatal rat cortical neurons. Prolonged application enhances neuroprotective efficacy.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Oxidoreductases; Animals; Animals, Newborn; Arginine; Cell Death; Cells, Cultured; Cerebral Cortex; Cyclic GMP; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Rats; Rats, Sprague-Dawley | 1993 |
Nitric oxide production during focal cerebral ischemia in rats.
Topics: Amino Acid Oxidoreductases; Analysis of Variance; Animals; Arginine; Arterial Occlusive Diseases; Brain; Cerebellum; Cerebral Arterial Diseases; Cerebral Cortex; Cyclic GMP; Functional Laterality; Ischemic Attack, Transient; Male; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Rats; Rats, Wistar | 1993 |
Endotoxin enhances hypoxic constriction of rat aorta and pulmonary artery through induction of EDRF/NO synthase.
Topics: Amino Acid Oxidoreductases; Animals; Aorta; Arginine; Cyclic GMP; Cycloheximide; Dose-Response Relationship, Drug; Endotoxins; Enzyme Induction; Hypoxia; In Vitro Techniques; Indomethacin; Nitric Oxide; Nitric Oxide Synthase; Phenylephrine; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Vasoconstriction | 1993 |
The effect of nitric oxide on the efficacy of synaptic transmission through the chick ciliary ganglion.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Action Potentials; Amino Acid Oxidoreductases; Animals; Animals, Newborn; Arginine; Calcium; Chickens; Cyclic GMP; Ganglia, Parasympathetic; Guanylate Cyclase; In Vitro Techniques; Long-Term Potentiation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Presynaptic Terminals; Synapses; Synaptic Transmission | 1993 |
Nitric oxide in the sensory function of the carotid body.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Carotid Body; Cats; Chemoreceptor Cells; Cyclic GMP; Female; Male; NADPH Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Oxygen; Partial Pressure; Stereoisomerism; Tissue Distribution | 1993 |
Differential regulation of cyclic GMP levels in the frontal cortex and the cerebellum of anesthetized rats by nitric oxide: an in vivo microdialysis study.
Topics: Animals; Arginine; Carbon Monoxide; Cerebellum; Chloral Hydrate; Cyclic GMP; Frontal Lobe; Male; Microdialysis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroarginine; Nitroprusside; Radioimmunoassay; Rats; Rats, Wistar; Signal Transduction | 1994 |
Nitric oxide modulates gamma-interferon-induced MHC class II antigen expression on rat astrocytes.
Topics: Animals; Arginine; Astrocytes; Cyclic AMP; Cyclic GMP; Histocompatibility Antigens Class II; Interferon-gamma; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Nitroprusside; Rats; Rats, Inbred Lew; Rats, Wistar | 1995 |
Effects of prolonged L-arginine administration on blood pressure in patients with essential hypertension (EH).
Topics: Adult; Arginine; Blood Pressure; Cyclic GMP; Fibrinolysis; Heart Rate; Humans; Hypertension; Injections, Intravenous; Male; Middle Aged; Nitrates; Nitrites; Radioimmunoassay | 1995 |
Effects of NO-donors, SIN-1 and GEA 3175 on prostacyclin and cGMP synthesis in cultured rat endothelial cells.
Topics: Animals; Arginine; Calcimycin; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Epoprostenol; Female; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Triazoles | 1995 |
Calcium- and protein kinase C-dependent basal tone in the aorta of hypertensive rats.
Topics: Acetylcholine; Animals; Aorta; Arginine; Calcium; Cyclic GMP; Hypertension; In Vitro Techniques; Male; Nitroprusside; Protein Kinase C; Rats; Rats, Sprague-Dawley; Vasomotor System | 1995 |
Ginsenosides of the protopanaxatriol group cause endothelium-dependent relaxation in the rat aorta.
Topics: Animals; Aorta, Thoracic; Arginine; Cyclic GMP; Endothelium, Vascular; Ginsenosides; In Vitro Techniques; Male; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Sapogenins; Saponins; Triterpenes; Vasodilation | 1995 |
Role of nitric oxide and cAMP in prostaglandin-induced pial arterial vasodilation.
Topics: Animals; Arginine; Cerebral Arteries; Cyclic AMP; Cyclic GMP; Dinoprostone; Epoprostenol; Female; Indomethacin; Male; Nitric Oxide; Nitroarginine; Nucleotides, Cyclic; Pia Mater; Prostaglandins; Swine; Vasodilation | 1995 |
Nitric oxide mediates chemoreceptor inhibition in the cat carotid body.
Topics: Animals; Arginine; Carotid Body; Cats; Chemoreceptor Cells; Citrulline; Cyclic GMP; Electric Stimulation; Evoked Potentials; Hypoxia; Immunohistochemistry; Nitric Oxide | 1995 |
Possible involvement of nitric oxide in carbachol-induced activation of transglutaminase in rat superior cervical sympathetic ganglia.
Topics: Animals; Arginine; Calcium; Carbachol; Cyclic GMP; Enzyme Activation; Female; Hemoglobins; In Vitro Techniques; Male; Methylene Blue; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Wistar; Superior Cervical Ganglion; Transglutaminases | 1995 |
Involvement of a nitric oxide-cyclic guanosine monophosphate pathway in control of human uterine contractility during pregnancy.
Topics: Adult; Analysis of Variance; Arginine; Cyclic GMP; Diethylamines; Female; Humans; In Vitro Techniques; Labor, Obstetric; Myometrium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pregnancy; Uterine Contraction | 1995 |
Renal hypertensive angiopathy. Comparison between chronic NO suppression and DOCA-salt intoxication.
Topics: Animals; Aorta; Arginine; Blood Pressure; Blood Urea Nitrogen; Body Weight; Creatinine; Cyclic GMP; Desoxycorticosterone; Disease Models, Animal; Hypertension, Renal; Hypertrophy, Left Ventricular; Male; Mortality; NG-Nitroarginine Methyl Ester; Proteinuria; Rats; Rats, Wistar; Renin-Angiotensin System | 1995 |
Endothelium-dependent relaxation resistant to NG-nitro-L-arginine in rat aorta.
Topics: Acetylcholine; Analysis of Variance; Animals; Aorta, Thoracic; Arginine; Atropine; Biological Factors; Cyclic GMP; Endothelium, Vascular; Glyburide; Indomethacin; Isometric Contraction; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroarginine; Norepinephrine; Oxyhemoglobins; Papaverine; Potassium Channel Blockers; Rats; Rats, Wistar; Tetraethylammonium; Tetraethylammonium Compounds | 1995 |
Leukotrienes stimulate pepsinogen secretion from guinea pig gastric chief cells by a nitric oxide-dependent pathway.
Topics: Animals; Arginine; Calcium; Cyclic GMP; Gastric Mucosa; Guinea Pigs; Inositol 1,4,5-Trisphosphate; L-Lactate Dehydrogenase; Leukotrienes; Male; Nitric Oxide; omega-N-Methylarginine; Pepsinogens | 1995 |
Increased aortic cyclic guanosine monophosphate concentration in experimental cirrhosis in rats: evidence for a role of nitric oxide in the pathogenesis of arterial vasodilation in cirrhosis.
Topics: Analysis of Variance; Animals; Aorta; Arginine; Blood Pressure; Cyclic GMP; Heart Rate; Liver Cirrhosis, Experimental; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Phenobarbital; Rats; Rats, Sprague-Dawley; Regression Analysis; Vasodilation | 1995 |
Contractile effects of diaspirin cross-linked hemoglobin (DCLHb) on isolated porcine blood vessels.
Topics: Acetylcholine; Analysis of Variance; Animals; Arginine; Arteries; Aspirin; Cyclic GMP; Endothelium, Vascular; Hemoglobins; In Vitro Techniques; Kinetics; Methemoglobin; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Organ Specificity; Potassium Chloride; Pulmonary Veins; Swine; Veins | 1995 |
Deficiency of endogenous arginine synthesis provokes hypertension by exhausting substrate arginine for nitric oxide synthesis.
Topics: Amino Acids; Animals; Arginine; Blood Pressure; Creatinine; Cyclic GMP; Eating; Hypertension; Intestine, Small; Muscles; Nitrates; Nitric Oxide; Orotic Acid; Pulse; Rats; Rats, Sprague-Dawley; Reference Values; Weight Loss | 1994 |
Elevation of cyclic GMP levels in the rat pineal gland induced by nitric oxide.
Topics: Animals; Arginine; Cyclic AMP; Cyclic GMP; Male; Nitric Oxide; Nitroprusside; Organ Culture Techniques; Pineal Gland; Rats; Rats, Sprague-Dawley | 1994 |
Endothelium-dependent relaxation resistant to N omega-nitro-L-arginine in the rat hepatic artery and aorta.
Topics: Acetylcholine; Animals; Aorta; Arginine; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Female; Hepatic Artery; In Vitro Techniques; Muscle, Smooth, Vascular; Nitroarginine; Phenylephrine; Potassium; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasodilation | 1994 |
Sodium nitroprusside modulates NMDA response in the rat supraoptic neurons in vitro.
Topics: Animals; Arginine; Cyclic GMP; Ferricyanides; In Vitro Techniques; Isosorbide Dinitrate; Kainic Acid; Male; Membrane Potentials; N-Methylaspartate; Neurons; Nitroarginine; Nitroprusside; Protein Kinases; Quisqualic Acid; Rats; Rats, Wistar; Supraoptic Nucleus | 1994 |
Role of nitric oxide/cyclic GMP in i.c.v. administered beta-endorphin- and (+)-cis-dioxolane-induced antinociception in the mouse.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesia; Analgesics; Animals; Arginine; beta-Endorphin; Cyclic GMP; Dioxolanes; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Hemoglobins; Injections, Intraventricular; Male; Methylene Blue; Mice; Mice, Inbred ICR; Morphine; Narcotic Antagonists; Nitric Oxide; Nitroarginine; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Stereoisomerism | 1994 |
Ligation of CD23 activates soluble guanylate cyclase in human monocytes via an L-arginine-dependent mechanism.
Topics: Antibodies, Monoclonal; Antigen-Antibody Complex; Arginine; Cells, Cultured; Cyclic AMP; Cyclic GMP; Enzyme Activation; Guanylate Cyclase; Humans; Immunoglobulin E; Interleukin-4; Monocytes; Nitric Oxide; omega-N-Methylarginine; Receptors, IgE | 1995 |
Potentiation of nitric oxide-mediated vascular relaxation by SC52608, a superoxide dismutase mimic.
Topics: Animals; Antioxidants; Aorta, Thoracic; Arginine; Blood Pressure; Chlorides; Cyclic GMP; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Male; Manganese Compounds; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Organometallic Compounds; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Vasodilation | 1995 |
cGMP and nitric oxide modulate thrombin-induced endothelial permeability. Regulation via different pathways in human aortic and umbilical vein endothelial cells.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Aorta; Arginine; Calcium; Capillary Permeability; Cyclic GMP; Endothelium, Vascular; Humans; Intracellular Membranes; NG-Nitroarginine Methyl Ester; Nitric Oxide; Thrombin; Umbilical Veins | 1995 |
Inhibition by lithium of cyclic GMP formation without inhibition of nitric oxide generation in the mouse neuroblastoma cell (N1E-115).
Topics: Animals; Arginine; Brain Neoplasms; Carbachol; Cyclic GMP; Guanylate Cyclase; Lithium; Mice; Muscarinic Antagonists; Neuroblastoma; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Tumor Cells, Cultured | 1994 |
Nitric oxide modulates rhythmic slow activity in rat hippocampal slices.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Arginine; Carbachol; Cyclic GMP; Electrophysiology; Hemoglobins; Hippocampus; In Vitro Techniques; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley | 1994 |
Uptake of atrial natriuretic peptide and production of cGMP in cultured human glomerular endothelial cells.
Topics: Arginine; Atrial Natriuretic Factor; Biological Transport, Active; Bradykinin; Calcium; Capillaries; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Guanylate Cyclase; Humans; Kidney Glomerulus; Kinetics; Models, Biological; Nitric Oxide; Nitroarginine; Oxyhemoglobins; Peptide Fragments | 1994 |
HS-142-1, a potent antagonist of natriuretic peptides in vitro and in vivo.
Topics: Animals; Arginine; Atrial Natriuretic Factor; Cell Line; Cyclic GMP; Furosemide; Glomerular Filtration Rate; Male; Natriuresis; Natriuretic Peptide, Brain; Natriuretic Peptide, C-Type; Nerve Tissue Proteins; Peptide Fragments; Polysaccharides; Proteins; Rats; Rats, Wistar; Receptors, Atrial Natriuretic Factor | 1994 |
[Nitric oxide and volatile anesthetics].
Topics: Anesthetics, Inhalation; Animals; Arginine; Brain; Cyclic GMP; NG-Nitroarginine Methyl Ester; Nitrous Oxide; Pulmonary Alveoli | 1994 |
Regulation of bradykinin sensitivity in peripheral sensory fibres of the neonatal rat by nitric oxide and cyclic GMP.
Topics: Animals; Animals, Newborn; Arginine; Bradykinin; Concanavalin A; Cyclic GMP; Indazoles; Methylene Blue; Nitric Oxide; Nitroprusside; Nociceptors; Rats; Receptors, Bradykinin; Spinal Cord | 1994 |
cGMP mediates the desensitization to bradykinin in isolated canine coronary arteries.
Topics: Animals; Arginine; Arteries; Bradykinin; Coronary Vessels; Cyclic GMP; Dogs; Drug Resistance; In Vitro Techniques; Methylene Blue; Molsidomine; Nitroarginine; Oxyhemoglobins; Potassium; Vasodilation; Vasodilator Agents | 1995 |
Evidence to suggest nitric oxide is an interstitial regulator of Leydig cell steroidogenesis.
Topics: Animals; Arginine; Cells, Cultured; Chorionic Gonadotropin; Cyclic GMP; Leydig Cells; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Testosterone | 1995 |
The cytoprotective role of nitric oxide in ischemia-reperfusion injury in the rat kidney.
Topics: Analysis of Variance; Animals; Arginine; Cyclic GMP; Ischemia; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Reperfusion Injury; Time Factors | 1995 |
Nitric oxide mediates activity-dependent synaptic suppression at developing neuromuscular synapses.
Topics: Action Potentials; Animals; Arginine; Cells, Cultured; Cyclic GMP; Hemoglobins; Neuromuscular Junction; Neuronal Plasticity; Nitric Oxide; omega-N-Methylarginine; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Synapses; Xenopus | 1995 |
The role of myoendothelial cell contact in non-nitric oxide-, non-prostanoid-mediated endothelium-dependent relaxation of porcine coronary artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arginine; Biological Factors; Bradykinin; Cells, Cultured; Coronary Vessels; Cyclic GMP; Endothelium, Vascular; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Papaverine; Potassium; Prostaglandin Endoperoxides, Synthetic; Swine; Thromboxane A2; Vasoconstrictor Agents | 1994 |
Endothelium-derived nitric oxide plays a larger role in pulmonary veins than in arteries of newborn lambs.
Topics: Acetylcholine; Animals; Animals, Newborn; Arginine; Bradykinin; Calcimycin; Cyclic GMP; Endothelium, Vascular; Guanylate Cyclase; In Vitro Techniques; Nitric Oxide; Nitroarginine; Pulmonary Artery; Pulmonary Veins; Radioimmunoassay; Sheep; Vascular Resistance | 1995 |
Nitric oxide-related vasoconstriction in lungs perfused with red cell lysate.
Topics: Animals; Arginine; Catalase; Cyclic GMP; Dialysis; Ethylmaleimide; Hemolysis; In Vitro Techniques; Indoles; Lung; Meclofenamic Acid; Nitric Oxide; Nitroprusside; Oxygen Consumption; Perfusion; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Vasoconstriction | 1995 |
Direct influence of melatonin on steroid, nonapeptide hormones, and cyclic nucleotide secretion by granulosa cells isolated from porcine ovaries.
Topics: Animals; Arginine; Cells, Cultured; Cyclic AMP; Cyclic GMP; Estradiol; Female; Granulosa Cells; Hormones; Melatonin; Nucleotides, Cyclic; Oxytocin; Progesterone; Swine | 1994 |
Monocyte chemoattractant protein 1 inhibits growth of rat vascular smooth muscle cells.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arginine; Arteriosclerosis; Cell Division; Cells, Cultured; Chemokine CCL2; Chemotactic Factors; Cyclic AMP; Cyclic GMP; DNA; Gene Expression; Humans; Indomethacin; Lipopolysaccharides; Muscle, Smooth, Vascular; omega-N-Methylarginine; Rats; Recombinant Proteins; Thymidine | 1995 |
Vasorelaxant mechanism of the new vasodilator, FK409.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Arginine; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Guanylate Cyclase; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitro Compounds; Nitroglycerin; omega-N-Methylarginine; Oxyhemoglobins; Rabbits; Rats; Rats, Sprague-Dawley; Solubility; Vasodilator Agents | 1993 |
Bradykinin and capsaicin stimulate cyclic GMP production in cultured rat dorsal root ganglion neurons via a nitrosyl intermediate.
Topics: Animals; Arginine; Bradykinin; Bradykinin Receptor Antagonists; Calcium; Capsaicin; Cells, Cultured; Cyclic GMP; Ganglia, Spinal; Guanylate Cyclase; Methylene Blue; Neurons; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Receptors, Bradykinin | 1993 |
Blockers of the L-arginine-nitric oxide-cyclic GMP pathway facilitate baroreceptor resetting.
Topics: Analysis of Variance; Animals; Aorta; Aortic Coarctation; Arginine; Blood Pressure; Cyclic GMP; Glyburide; Guanylate Cyclase; Male; Methylene Blue; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Pressoreceptors; Rats; Rats, Wistar | 1994 |
Growth hormone-releasing factor increases somatostatin release and mRNA levels in the rat periventricular nucleus via nitric oxide by activation of guanylate cyclase.
Topics: Animals; Arginine; Cyclic GMP; Cycloheximide; Dibutyryl Cyclic GMP; Enzyme Activation; Gonadotropin-Releasing Hormone; Guanylate Cyclase; In Vitro Techniques; Male; Models, Biological; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; RNA, Messenger; Somatostatin | 1994 |
Endogenous nitric oxide inhibits NMDA- and kainate- responses by a negative feedback system in rat hippocampal neurons.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Arginine; Calcium; Cells, Cultured; Cyclic GMP; Feedback; Glutamates; Glutamic Acid; Hemoglobins; Hippocampus; Kainic Acid; N-Methylaspartate; Neurons; Nitric Oxide; Nitroarginine; Osmolar Concentration; Rats; Rats, Wistar; Receptors, Amino Acid | 1993 |
Nitric oxide has no chronotropic effect in right atria isolated from rat heart.
Topics: Acetylcholine; Aminoquinolines; Animals; Aorta, Thoracic; Arginine; Cyclic GMP; Guanylate Cyclase; Heart Atria; Heart Rate; In Vitro Techniques; Male; Methylene Blue; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroarginine; Norepinephrine; Parasympathetic Nervous System; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Vasodilator Agents | 1994 |
L-arginine attenuates platelet reactivity in hypercholesterolemic rabbits.
Topics: Adenosine Diphosphate; Animals; Arginine; Blood Platelets; Calcium; Cholesterol; Cholesterol, Dietary; Cyclic GMP; Hypercholesterolemia; Intracellular Membranes; Male; Platelet Aggregation; Rabbits | 1994 |
Functional analysis of vascular dysfunction in cyclosporin treated rats.
Topics: Acetylcholine; Animals; Aorta; Arginine; Cyclic GMP; Cyclosporins; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nephrectomy; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroglycerin; Rats; Rats, Wistar | 1994 |
Non-adrenergic, non-cholinergic relaxation and levels of cyclic nucleotides in rabbit lower urinary tract.
Topics: Animals; Arginine; Cyclic AMP; Cyclic GMP; Electric Stimulation; Female; In Vitro Techniques; Methylene Blue; Muscle Relaxation; Nitric Oxide; Nitroarginine; Rabbits; Urethra | 1994 |
Pharmacologic evidence that spinal muscarinic analgesia is mediated by an L-arginine/nitric oxide/cyclic GMP cascade in rats.
Topics: Analgesia; Animals; Arginine; Cyclic GMP; Dioxolanes; Dose-Response Relationship, Drug; Injections, Spinal; Male; Methylene Blue; Muscarinic Agonists; Nitric Oxide; Nitroarginine; Rats; Rats, Sprague-Dawley; Spinal Cord | 1994 |
Nitric oxide inhibition causes intrauterine growth retardation and hind-limb disruptions in rats.
Topics: Amniotic Fluid; Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Female; Fetal Diseases; Fetal Growth Retardation; Fetus; Hemorrhage; Hindlimb; Necrosis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Placenta; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley | 1994 |
Cyclic GMP formation in rat cerebellar slices is stimulated by endothelins via nitric oxide formation and by sarafotoxins via formation of carbon monoxide.
Topics: Animals; Arginine; Carbon Monoxide; Cerebellum; Cyclic GMP; Endothelin Receptor Antagonists; Endothelins; GTP-Binding Proteins; In Vitro Techniques; Male; Nitric Oxide; Nitroarginine; Peptides; Peptides, Cyclic; Rats; Receptors, Endothelin; Signal Transduction; Viper Venoms | 1994 |
Nitric oxide regulates peptide release from parasympathetic nerves and vascular reactivity to vasoactive intestinal polypeptide in vivo.
Topics: Animals; Arginine; Atropine; Blood Pressure; Cyclic GMP; Electric Stimulation; Female; Male; Milrinone; Neuropeptides; Nitric Oxide; Nitroarginine; Nitroprusside; Parasympathetic Nervous System; Phosphodiesterase Inhibitors; Pyridones; Regional Blood Flow; Submandibular Gland; Swine; Vascular Resistance; Vasoactive Intestinal Peptide; Vasodilation | 1994 |
Effect of axotomy on nitric oxide-dependent cyclic GMP production of rat superior cervical sympathetic ganglia in response to norepinephrine.
Topics: Animals; Arginine; Axons; Cyclic GMP; Denervation; Female; Ganglia, Sympathetic; Male; Nitric Oxide; Norepinephrine; Rats; Rats, Wistar | 1994 |
Contribution of nitric oxide to the endothelium-dependent hyperpolarization in rat aorta.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Carbachol; Cyclic GMP; Endothelium, Vascular; In Vitro Techniques; Membrane Potentials; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroglycerin; omega-N-Methylarginine; Rats; Rats, Wistar | 1994 |
Regional differentiation in rat aorta: L-arginine metabolism and cGMP content in vitro.
Topics: Animals; Aorta; Arginine; Biological Transport; Cell Differentiation; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Female; Male; Osmolar Concentration; Rats; Rats, Inbred Strains | 1994 |
Cyclic GMP-independent relaxation and hyperpolarization with acetylcholine in guinea-pig coronary artery.
Topics: Acetylcholine; Animals; Arginine; Biological Factors; Coronary Vessels; Cyclic GMP; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Nitric Oxide; omega-N-Methylarginine; Oxyhemoglobins; Scorpion Venoms; Vasodilation | 1994 |
Lack of importance of NO in beta-adrenoceptor-mediated relaxation of large epicardial canine coronary arteries.
Topics: Animals; Arginine; Coronary Vessels; Cyclic GMP; Dogs; Endothelium, Vascular; In Vitro Techniques; Isoproterenol; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Receptors, Adrenergic, beta; Vasodilation | 1994 |
Modulation of cyclic guanosine monophosphate production during Escherichia coli septic shock.
Topics: Animals; Arginine; Bacteremia; Carbon Dioxide; Cyclic GMP; Escherichia coli Infections; Lactates; Lactic Acid; Male; Nitric Oxide; omega-N-Methylarginine; Rabbits; Shock, Septic | 1994 |
N-Methyl-D-aspartate receptor-mediated signaling in the supraoptic nucleus involves activation of a nitric oxide-dependent pathway.
Topics: Animals; Arginine; Calcimycin; Chlorisondamine; Cyclic GMP; Heart Rate; Male; Microinjections; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Piperazines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Supraoptic Nucleus | 1994 |
Plasma endothelin levels and vascular effects of intravenous L-arginine infusion in subjects with uncomplicated insulin-dependent diabetes mellitus.
Topics: Adult; Arginine; Atrial Natriuretic Factor; Blood Pressure; Citrulline; Cyclic GMP; Diabetes Mellitus, Type 1; Endothelins; Extracellular Space; Humans; Infusions, Intravenous; Male; Nitric Oxide; Sodium Chloride | 1994 |
Altered nitric oxide production and exogenous nitric oxide do not affect the proliferation of rat mesangial cells.
Topics: Animals; Arginine; Cell Division; Cells, Cultured; Cyclic GMP; Glomerular Mesangium; Interleukin-1; Lipopolysaccharides; Molsidomine; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley | 1994 |
Evidence that lithium induces a glutamatergic: nitric oxide-mediated response in rat brain.
Topics: Animals; Arginine; Cerebral Cortex; Cyclic GMP; Drinking Behavior; Glutamates; Kainic Acid; Lithium Chloride; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Polyuria; Rats; Rats, Wistar; Stereotyped Behavior | 1994 |
L-NNA decreases cortical hyperemia and brain cGMP levels following CO2 inhalation in Sprague-Dawley rats.
Topics: Acetylcholine; Administration, Inhalation; Administration, Topical; Animals; Arginine; Brain; Carbon Dioxide; Cerebral Cortex; Cerebrovascular Circulation; Cyclic GMP; Hypercapnia; Hyperemia; Male; Nitroarginine; Rats; Rats, Sprague-Dawley; Vasodilation | 1994 |
Role of nitric oxide (EDRF) in radiocontrast acute renal failure in rats.
Topics: Acute Kidney Injury; Animals; Arginine; Blood Pressure; Cyclic GMP; Diatrizoate; Female; Nitrates; Nitric Oxide; Nitrites; Nitroarginine; Rats; Rats, Sprague-Dawley; Sodium; Time Factors | 1994 |
Non-classical glutamate receptors, blocked by both NMDA and non-NMDA antagonists, stimulate nitric oxide production in neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Arginine; Cells, Cultured; Corpus Striatum; Cyclic GMP; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Mice; N-Methylaspartate; Neurons; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Pregnancy; Quinoxalines; Quisqualic Acid; Receptors, Glutamate | 1993 |
Evidence against vasoactive intestinal polypeptide as the relaxant neurotransmitter in human cavernosal smooth muscle.
Topics: Arginine; Chymotrypsin; Cyclic GMP; Electric Stimulation; Humans; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth; Neurotransmitter Agents; Nitric Oxide; Nitroarginine; Penis; Vasoactive Intestinal Peptide | 1993 |
Human immunodeficiency virus type 1 coat protein neurotoxicity mediated by nitric oxide in primary cortical cultures.
Topics: Animals; Arginine; Calcium; Cell Death; Cell Survival; Cells, Cultured; Cerebral Cortex; Cyclic GMP; Dantrolene; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Fetus; Glutamates; Glutamic Acid; Hemoglobins; HIV Envelope Protein gp120; HIV-1; Inositol Phosphates; Models, Neurological; Neurons; Neurotoxins; Nifedipine; Nitric Oxide; Nitroarginine; Quinoxalines; Rats | 1993 |
Adrenergic stimulation of cyclic GMP formation requires NO-dependent activation of cytosolic guanylate cyclase in rat pinealocytes.
Topics: Animals; Arginine; Cells, Cultured; Cyclic GMP; Cytosol; Enzyme Activation; Guanylate Cyclase; Methylene Blue; Nitric Oxide; omega-N-Methylarginine; Pineal Gland; Rats; Sympathomimetics | 1993 |
Notes on the acetylcholine-induced relaxation of porcine coronary arteries.
Topics: Acetylcholine; Animals; Arginine; Coronary Vessels; Cyclic GMP; Dose-Response Relationship, Drug; Drug Synergism; Endothelium, Vascular; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Radioimmunoassay; Swine; Vasoconstriction; Vasodilation | 1994 |
Thapsigargin, a Ca(2+)-ATPase inhibitor, relaxes rat aorta via nitric oxide formation.
Topics: Aminoquinolines; Animals; Aorta, Thoracic; Arginine; Calcium; Calcium-Transporting ATPases; Cyclic GMP; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Rats; Rats, Wistar; SRS-A; Terpenes; Thapsigargin | 1994 |
Mechanisms of the endothelial toxicity of cyclosporin A. Role of nitric oxide, cGMP, and Ca2+.
Topics: Animals; Aorta; Arginine; Calcium; Cyclic GMP; Cyclosporine; Endothelium, Vascular; Femoral Artery; In Vitro Techniques; Male; Nitric Oxide; Rats; Rats, Wistar; Vasodilation | 1994 |
Neuronal pathway involved in nitric oxide-mediated descending relaxation in rat ileum.
Topics: Animals; Arginine; Cholinergic Antagonists; Cyclic GMP; Dose-Response Relationship, Drug; Ileum; Indoles; Male; Muscle Relaxation; Muscle, Smooth; Nicotine; Nitric Oxide; Nitroarginine; Rats; Rats, Wistar; Receptors, Cholinergic; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tropanes; Tropisetron | 1993 |
Endotoxin-induced nitric oxide synthesis in the perfused rat liver: effects of L-arginine and ammonium chloride.
Topics: Ammonium Chloride; Animals; Arginine; Cyclic GMP; Endotoxins; Liver; Male; Nitric Oxide; Oxygen; Perfusion; Rats; Rats, Wistar; Salmonella typhimurium; Urea | 1994 |
Effects of nitric oxide on red blood cells: changes in erythrocyte resistance to hypotonic hemolysis and potassium efflux by experimental maneuvers that decrease nitric oxide.
Topics: Adult; Animals; Arginine; Cyclic GMP; Erythrocytes; Female; Hemolysis; Humans; Hypotonic Solutions; Kinetics; Male; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Potassium; Rats; Rats, Wistar | 1994 |
Endothelin-1 production by rat inner medullary collecting duct: effect of nitric oxide, cGMP, and immune cytokines.
Topics: Animals; Arginine; Atrial Natriuretic Factor; Base Sequence; Cells, Cultured; Cyclic GMP; Dibutyryl Cyclic GMP; DNA Primers; Endothelins; Interferon-gamma; Kidney Medulla; Kidney Tubules, Collecting; Kinetics; Male; Molecular Sequence Data; Nitric Oxide; omega-N-Methylarginine; Penicillamine; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; RNA, Messenger; S-Nitroso-N-Acetylpenicillamine; Time Factors; Tumor Necrosis Factor-alpha; Vasodilator Agents | 1994 |
Endothelium-dependent phosphorylation of vasodilator-stimulated protein in platelets during coronary passage.
Topics: Acetylcholine; Animals; Arginine; Blood Platelets; Coronary Circulation; Coronary Vessels; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Epoprostenol; Female; Humans; Indomethacin; Male; Muscle, Smooth, Vascular; Nitroarginine; Nitroprusside; Phosphoproteins; Phosphorylation; Rabbits | 1994 |
The production of nitric oxide in endothelial cells by amphiphiles.
Topics: Animals; Arginine; Cattle; Cyclic GMP; Digitonin; Endothelium, Vascular; In Vitro Techniques; Lysophosphatidylcholines; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rabbits | 1994 |
The possible role of angiotensin II subtype AT2 receptors in endothelial cells and isolated ischemic rat hearts.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arginine; Bradykinin; Cattle; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Female; In Vitro Techniques; Male; Myocardial Ischemia; Nitric Oxide; Nitroarginine; Oligopeptides; Rats; Rats, Wistar; Receptors, Angiotensin | 1993 |
L-arginine inhibits neointimal formation following balloon injury.
Topics: Angioplasty, Balloon; Animals; Arginine; Cyclic GMP; Hyperplasia; Muscle, Smooth, Vascular; Nitric Oxide; Rats | 1994 |
Nitric oxide production regulates cGMP formation and calcium influx in pancreatic acinar cells.
Topics: Animals; Arginine; Calcium; Carbachol; Cyclic GMP; Guinea Pigs; Indomethacin; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Pancreas; Rats | 1994 |
Effects of inhaled nitric oxide on pulmonary hemodynamics and gas exchange in an ovine model of ARDS.
Topics: Administration, Inhalation; Animals; Arginine; Cyclic GMP; Disease Models, Animal; Hemodynamics; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxygen Consumption; Pulmonary Circulation; Pulmonary Gas Exchange; Respiratory Distress Syndrome; Respiratory Mechanics; Sheep; Therapeutic Irrigation | 1994 |
Long-term administration of L-arginine, L-NAME, and the exogenous NO donor molsidomine modulates urinary nitrate and cGMP excretion in rats.
Topics: Animals; Arginine; Blood Pressure; Body Weight; Cholesterol; Chromatography, Gas; Cyclic GMP; Heart; Male; Molsidomine; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Organ Size; Rats; Rats, Wistar; Time Factors | 1994 |
Involvement of cyclic AMP and nitric oxide in immunoglobulin E-dependent activation of Fc epsilon RII/CD23+ normal human keratinocytes.
Topics: Antibodies, Monoclonal; Arginine; Cell Division; Cell Separation; Cells, Cultured; Cyclic AMP; Cyclic GMP; Humans; Immunoglobulin E; Immunohistochemistry; In Situ Hybridization; Infant, Newborn; Interleukin-6; Keratinocytes; Male; Nitrates; Nitric Oxide; Receptors, IgE; RNA, Messenger; Signal Transduction; Skin; Tumor Necrosis Factor-alpha | 1994 |
Human alveolar macrophage mediated vasodilation and the role of arginine compounds.
Topics: Adult; Animals; Aorta; Arginine; Cyclic GMP; Female; Humans; Macrophage Activation; Macrophages, Alveolar; Male; Rats; Rats, Sprague-Dawley; Vasodilation | 1994 |
Effects of L- and D-arginine and some related esters on the cytosolic mechanisms of alpha-thrombin-induced human platelet activation.
Topics: Adenosine Diphosphate; Apyrase; Arachidonic Acids; Arginine; Blood Platelets; Cyclic GMP; Cytosol; Humans; In Vitro Techniques; Indomethacin; Kinetics; Nitroprusside; Platelet Activation; Platelet Aggregation Inhibitors; Sodium-Hydrogen Exchangers; Spectrometry, Fluorescence; Stereoisomerism; Thrombin | 1993 |
Dissociation of cyclic GMP level from relaxation of the distal, but not the proximal colon of rats.
Topics: Animals; Arginine; Atrial Natriuretic Factor; Colon; Cyclic GMP; Electric Stimulation; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitroarginine; Rats; Rats, Wistar; Vasoactive Intestinal Peptide | 1993 |
Gestational changes in L-arginine-induced relaxation of pregnant rat and human myometrial smooth muscle.
Topics: Animals; Arginine; Carbachol; Cyclic GMP; Female; Humans; In Vitro Techniques; Muscle, Smooth; Myometrium; Nifedipine; Potassium Chloride; Pregnancy; Pregnancy, Animal; Rats; Uterine Contraction | 1993 |
Inhibitory effect of CO on internal anal sphincter: heme oxygenase inhibitor inhibits NANC relaxation.
Topics: Anal Canal; Animals; Arginine; Carbon Monoxide; Cyclic AMP; Cyclic GMP; Electric Stimulation; Female; Heme Oxygenase (Decyclizing); In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Nervous System Physiological Phenomena; Nitric Oxide; Nitroarginine; Opossums; Protoporphyrins | 1993 |
Pulmonary endothelial nitric oxide production is developmentally regulated in the fetus and newborn.
Topics: Aging; Animals; Animals, Newborn; Arginine; Cyclic GMP; Embryonic and Fetal Development; Endothelium, Vascular; Fetus; In Vitro Techniques; Nitric Oxide; Oxygen; Pulmonary Artery; Sheep | 1993 |
L-arginine inhibits neointimal formation following balloon injury.
Topics: Animals; Arginine; Blood Pressure; Body Weight; Carotid Arteries; Carotid Artery Injuries; Catheterization; Cyclic GMP; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Stereoisomerism; Tunica Intima | 1993 |
Possible involvement of nitric oxide in arginine-induced analgesia.
Topics: Analgesics; Animals; Arginine; Cyclic GMP; Injections, Intraventricular; Male; Mice; Nitric Oxide; Nitroprusside; Nociceptors; omega-N-Methylarginine; Pain Threshold | 1993 |
The vasodilatory effect of endogenous nitric oxide is a major counter-regulatory mechanism in the spontaneously hypertensive rat.
Topics: Animals; Arginine; Blood Pressure; Cyclic GMP; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Organ Size; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasodilation | 1993 |
Inhibition of nitric oxide formation does not protect murine cortical cell cultures from N-methyl-D-aspartate neurotoxicity.
Topics: Animals; Arginine; Cell Death; Cells, Cultured; Cerebral Cortex; Cyclic GMP; Dextrorphan; Mice; N-Methylaspartate; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Rats | 1993 |
Cytokines regulate L-arginine-dependent cyclic GMP production in rat glial cells.
Topics: Animals; Arginine; Astrocytes; Cells, Cultured; Cyclic GMP; Cytokines; Dexamethasone; Lipopolysaccharides; Neuroglia; Nitrites; Rats; Tumor Cells, Cultured | 1993 |
Increased vascular responsiveness to norepinephrine in rats with heart failure is endothelium dependent. Dissociation of basal and stimulated nitric oxide release.
Topics: Animals; Aorta, Thoracic; Arginine; Cyclic GMP; Endothelium, Vascular; Heart Failure; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Vasoconstriction; Vasoconstrictor Agents | 1994 |
Nitric oxide-induced microvascular permeability alterations: a regulatory role for cGMP.
Topics: Animals; Arginine; Atrial Natriuretic Factor; Capillary Permeability; Cats; Cyclic GMP; Intestines; Methylene Blue; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Regional Blood Flow | 1993 |
Angiotensin-converting enzyme inhibitors unmask endogenous kinin production by bovine coronary artery endothelium.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Bradykinin; Cattle; Coronary Vessels; Cyclic GMP; Endothelium, Vascular; In Vitro Techniques; Isoquinolines; Nitric Oxide; Nitroarginine; Ramipril; Tetrahydroisoquinolines; Vasodilation | 1993 |
Endothelium-derived relaxing factor, hypertension and chronic parathyroidectomy in spontaneously hypertensive and Wistar-Kyoto rats.
Topics: Acetylcholine; Animals; Aorta; Arginine; Calcium; Cyclic GMP; Drug Interactions; Extracellular Space; Hypertension; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Norepinephrine; Parathyroid Glands; Parathyroidectomy; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1993 |
Role of superoxide anions in the mediation of endothelium-dependent contractions.
Topics: Animals; Arginine; Calcimycin; Cyclic AMP; Cyclic GMP; Dogs; Endothelium, Vascular; Free Radicals; In Vitro Techniques; NG-Nitroarginine Methyl Ester; Prostaglandin-Endoperoxide Synthases; Superoxide Dismutase; Superoxides; Vasoconstriction | 1994 |
Methylene blue enhanced photorelaxation in aorta, pulmonary artery and corpus cavernosum.
Topics: Animals; Aorta; Arginine; Cyclic GMP; Hemoglobins; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroarginine; Penis; Photosensitizing Agents; Pulmonary Artery; Rabbits; Ultraviolet Rays | 1993 |
Mediation by nitric oxide of neurally-induced human cerebral artery relaxation.
Topics: Arginine; Cerebral Arteries; Cyclic GMP; Electric Stimulation; Humans; In Vitro Techniques; Nicotine; Nitric Oxide; Nitroarginine; Vasodilation | 1993 |
Hypoxia causes an abnormal contractile response in the atherosclerotic rabbit aorta. Implication of reduced nitric oxide and cGMP production.
Topics: Animals; Aorta; Arginine; Arteriosclerosis; Calcium; Cell Hypoxia; Cyclic GMP; Disease Models, Animal; Endothelium, Vascular; Male; Methylene Blue; Nitric Oxide; Nitroarginine; Rabbits; Serotonin; Vasoconstriction | 1993 |
Nitric oxide mediates cytokine-induced inhibition of insulin secretion by human islets of Langerhans.
Topics: Arginine; Cyclic GMP; Diabetes Mellitus, Type 1; Electron Spin Resonance Spectroscopy; Humans; In Vitro Techniques; Insulin; Insulin Secretion; Interferon-gamma; Interleukin-1; Islets of Langerhans; Nitric Oxide; Nitrites; omega-N-Methylarginine; Recombinant Proteins; Secretory Rate; Tumor Necrosis Factor-alpha | 1993 |
Endothelium-dependent vasorelaxation evoked by desmopressin and involvement of nitric oxide in rat aorta.
Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Aorta; Arginine; Cyclic GMP; Deamino Arginine Vasopressin; Endothelium, Vascular; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Wistar; Superoxide Dismutase; Vasodilation | 1993 |
Exogenous cGMP prevents decrease in diuresis and natriuresis induced by inhibition of NO synthesis.
Topics: Animals; Arginine; Blood Pressure; Cyclic GMP; Diuresis; Glomerular Filtration Rate; Male; Natriuresis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Renal Circulation | 1993 |
Endothelial L-arginine pathway and relaxations to vasopressin in canine basilar artery.
Topics: Animals; Arginine; Basilar Artery; Cyclic GMP; Dogs; Endothelium, Vascular; In Vitro Techniques; Molsidomine; Nitric Oxide; Nitroarginine; Vasodilation; Vasopressins | 1993 |
Nitric oxide and cGMP: mediators of pelvic nerve-stimulated erection in dogs.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Arginine; Cyclic GMP; Dogs; Electric Stimulation; Male; Methylene Blue; Nervous System Physiological Phenomena; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pelvis; Penile Erection; Purinones | 1993 |
Involvement of endothelium-derived relaxing factor in the pressure control of renin secretion from isolated perfused kidney.
Topics: Acetylcholine; Angiotensin I; Animals; Arginine; Atrial Natriuretic Factor; Cyclic GMP; Diuresis; In Vitro Techniques; Isoproterenol; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Perfusion; Pressure; Rats; Rats, Inbred Strains; Renin | 1993 |
The calmodulin antagonist calmidazolium stimulates release of nitric oxide in neuroblastoma N1E-115 cells.
Topics: Animals; Arginine; Calmodulin; Cyclic GMP; Dose-Response Relationship, Drug; Hemoglobins; Imidazoles; Kinetics; Mice; Neuroblastoma; Nitric Oxide; omega-N-Methylarginine; Tumor Cells, Cultured | 1993 |
Activation of distinct cAMP- and cGMP-dependent pathways by relaxant agents in isolated gastric muscle cells.
Topics: Aminoquinolines; Animals; Arginine; Cell Separation; Colon; Cyclic AMP; Cyclic GMP; Digestive System; Digestive System Physiological Phenomena; Enzyme Activation; Gastric Fundus; Guinea Pigs; Isoproterenol; Muscle Relaxation; Muscles; Nitrates; Nitric Acid; Nitroarginine; Nitroprusside; Protein Kinase C; SRS-A; Vasoactive Intestinal Peptide | 1993 |
Role of endothelium in biphasic hypoxic response of the isolated pulmonary artery in the rat.
Topics: Animals; Arginine; Cyclic GMP; Endothelium, Vascular; Hypoxia; Male; Nitric Oxide; omega-N-Methylarginine; Pulmonary Artery; Rats; Rats, Sprague-Dawley | 1993 |
Arterial size determines the enhancement of contractile responses after suppression of endothelium-derived relaxing factor formation.
Topics: Animals; Aorta; Arginine; Arteries; Cyclic GMP; Endothelium, Vascular; Female; Femoral Artery; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Nitroprusside; Norepinephrine; Rabbits; Saponins; Vasodilation | 1993 |
Influence of endothelium on induction of the L-arginine-nitric oxide pathway in rat aortas.
Topics: Animals; Aorta; Arginine; Cyclic GMP; Cycloheximide; Endothelium, Vascular; Male; Methylene Blue; Neural Pathways; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Rats; Rats, Wistar; Time Factors | 1993 |
Endothelin-3-induced relaxation of rat thoracic aorta: a role for nitric oxide formation.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Calmodulin; Cyclic GMP; Endothelins; Hemoglobins; Imidazoles; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Rats; Rats, Wistar | 1993 |
Nitric oxide affects mammalian distal colonic smooth muscle by tonic neural inhibition.
Topics: Acetylcholine; Animals; Arginine; Colon; Cyclic GMP; In Vitro Techniques; Isometric Contraction; Male; Muscle Contraction; Muscle, Smooth; Neural Inhibition; Neurons; Nitric Oxide; omega-N-Methylarginine; Radioimmunoassay; Rats; Rats, Wistar; Tetrodotoxin | 1993 |
Effects of physostigmine and some nitric oxide-cyclic GMP-related compounds on muscarinic receptor-mediated autoinhibition of hippocampal acetylcholine release.
Topics: Acetylcholine; Animals; Arginine; Atropine; Bucladesine; Cyclic GMP; Dibutyryl Cyclic GMP; Electric Stimulation; Hippocampus; In Vitro Techniques; Kinetics; Male; Nitric Oxide; Nitroarginine; Nitroglycerin; Nitroprusside; Physostigmine; Rats; Rats, Wistar; Receptors, Muscarinic | 1993 |
Propofol stimulates nitric oxide release from cultured porcine aortic endothelial cells.
Topics: Animals; Aorta; Arginine; Blood Pressure; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Hemoglobins; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Propofol; Swine; Vasodilation | 1993 |
L-arginine exerts a dual role in nociceptive processing in the brain: involvement of the kyotorphin-Met-enkephalin pathway and NO-cyclic GMP pathway.
Topics: Analgesics; Animals; Arginine; Brain; Cyclic GMP; Endorphins; Enkephalin, Methionine; Injections, Intraventricular; Male; Methylene Blue; Mice; Mice, Inbred Strains; Naloxone; Naltrexone; Narcotic Antagonists; Neural Pathways; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nociceptors; Pain Measurement; Spinal Cord | 1993 |
Role of nitric oxide as an inhibitory neurotransmitter in the canine pyloric sphincter.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Arginine; Cyclic GMP; Dogs; Duodenum; Electric Stimulation; Female; Gastric Mucosa; In Vitro Techniques; Intercellular Junctions; Intestinal Mucosa; Male; Membrane Potentials; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Oxyhemoglobins; Phentolamine; Propranolol; Purinones; Pylorus; Stomach; Tetrodotoxin | 1993 |
Nitric oxide promotes DNA synthesis and cyclic GMP formation in endothelial cells from postcapillary venules.
Topics: Animals; Arginine; Cattle; Cells, Cultured; Coronary Vessels; Cyclic GMP; DNA; DNA Replication; Endothelium, Vascular; Fibroblast Growth Factor 2; Isosorbide Dinitrate; Kinetics; Nitric Oxide; Nitroglycerin; Nitroprusside; omega-N-Methylarginine; Thymidine; Venules | 1993 |
Changes in endothelium-dependent relaxation and levels of cyclic nucleotides in the perfused mesenteric arterial bed from streptozotocin-induced diabetic rats.
Topics: Animals; Arginine; Blood Pressure; Cyclic AMP; Cyclic GMP; Diabetes Mellitus, Experimental; Endothelium, Vascular; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Vasodilation | 1993 |
Involvement of nitric oxide in fading of 5-hydroxytryptamine-induced vasocontraction.
Topics: Animals; Arginine; Cyclic GMP; Endothelium, Vascular; Hemoglobins; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Phenylephrine; Rats; Rats, Wistar; Serotonin; Serotonin Antagonists; Vasoconstriction | 1993 |
Nitric oxide mediates interleukin-1-induced prostaglandin E2 production by vascular smooth muscle cells.
Topics: Animals; Aorta; Arginine; Cells, Cultured; Cyclic GMP; Dinoprostone; Humans; Interleukin-1; Kinetics; Muscle, Smooth, Vascular; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Rats; Recombinant Proteins; Superoxide Dismutase; Time Factors | 1993 |
Lysophosphatidylcholine-induced vascular relaxation and production of cGMP are mediated by endothelium-derived relaxing factor.
Topics: Animals; Arginine; Cattle; Cyclic GMP; Histamine; Lysophosphatidylcholines; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pulmonary Artery; Vasodilation | 1993 |
Thapsigargin induces an endothelium-dependent, intracellular calcium ion-dependent vasodilation in vitro.
Topics: Animals; Aorta, Thoracic; Arginine; Calcium; Carcinogens; Cyclic GMP; Endothelium, Vascular; Female; Guinea Pigs; In Vitro Techniques; Intracellular Fluid; Male; Muscle Contraction; Muscle Relaxation; Nitric Oxide; Nitroarginine; Terpenes; Thapsigargin; Vasodilation | 1993 |
Attenuation of contractions to acetylcholine in canine bronchi by an endogenous nitric oxide-like substance.
Topics: Acetylcholine; Animals; Arginine; Bronchi; Catalase; Cyclic GMP; Dogs; Female; In Vitro Techniques; Isometric Contraction; Male; Methylene Blue; Muscle, Smooth; Nitric Oxide; Nitroarginine; Oxyhemoglobins; Superoxide Dismutase | 1993 |
Evidence of L-arginine/nitric oxide pathway in endothelium and smooth muscle of human internal mammary artery.
Topics: Acetylcholine; Aged; Arginine; Calcimycin; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Humans; In Vitro Techniques; Kinetics; Male; Mammary Arteries; Middle Aged; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; omega-N-Methylarginine | 1993 |
Atrial natriuretic factor influences in vivo plasma, lung and aortic wall cGMP concentrations differently.
Topics: Animals; Aorta; Aorta, Abdominal; Aorta, Thoracic; Arginine; Atrial Natriuretic Factor; Blood Pressure; Body Weight; Cyclic GMP; Disease Models, Animal; Infusions, Intravenous; Lung; Male; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Rats; Rats, Wistar; Renin | 1993 |
Effect of nitric oxide and cyclooxygenase products on vascular resistance in dog and rat lungs.
Topics: Animals; Arginine; Blood Pressure; Cyclic GMP; Dogs; Female; In Vitro Techniques; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Perfusion; Prostaglandin-Endoperoxide Synthases; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Vascular Resistance | 1993 |
Endothelium-dependent vasorelaxing activity of wine and other grape products.
Topics: Animals; Aorta; Arginine; Cyclic GMP; Endothelium, Vascular; Fruit; In Vitro Techniques; Male; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Plant Extracts; Rats; Rats, Sprague-Dawley; Vasodilation; Wine | 1993 |
Neurogenic and non-neurogenic relaxations caused by nicotine in isolated dog superficial temporal artery.
Topics: Adrenergic Fibers; Animals; Arginine; Cyclic GMP; Dinoprost; Dogs; Electric Stimulation; Endothelium, Vascular; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle Tonus; Muscle, Smooth, Vascular; Nicotine; Nitric Oxide; Nitroarginine; Temporal Arteries | 1993 |
Potassium channel-mediated relaxation to acetylcholine in rabbit arteries.
Topics: Acetylcholine; Animals; Aorta, Abdominal; Aorta, Thoracic; Arginine; Cyclic GMP; Endothelium, Vascular; Glyburide; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Potassium; Potassium Channels; Rabbits; Stimulation, Chemical; Tetraethylammonium; Tetraethylammonium Compounds; Tolbutamide | 1993 |
L-arginine infusion has no effect on systemic haemodynamics in normal volunteers, or systemic and pulmonary haemodynamics in patients with elevated pulmonary vascular resistance.
Topics: Adult; Arginine; Blood Pressure; Cyclic GMP; Hemodynamics; Humans; Hypertension, Pulmonary; Infusions, Intravenous; Male; Pulmonary Circulation; Pulse; Sclerosis; Skin Temperature; Vascular Resistance | 1993 |
Insulin attenuates agonist-mediated calcium mobilization in cultured rat vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Arginine; Calcium; Cells, Cultured; Cyclic GMP; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Insulin; Male; Muscle, Smooth, Vascular; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin | 1993 |
Interaction of nitric oxide and cyclic guanosine 3',5'-monophosphate in erythropoietin production.
Topics: Animals; Arginine; Cyclic GMP; Erythropoietin; Female; Humans; In Vitro Techniques; Mice; Mice, Inbred C3H; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Polycythemia; Tumor Cells, Cultured | 1993 |
The effect of endothelins on nitric oxide and prostacyclin production from human umbilical vein, porcine aorta and bovine carotid artery endothelial cells in culture.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aorta; Arginine; Bradykinin; Carotid Arteries; Cattle; Cells, Cultured; Cyclic GMP; Endothelins; Endothelium, Vascular; Epoprostenol; Female; Hemoglobins; Histamine; Humans; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Pregnancy; Swine; Umbilical Veins | 1993 |
Localization of nitric oxide-related substances in the peripheral nervous tissues.
Topics: Animals; Arginine; Citrulline; Cyclic GMP; Ganglia, Spinal; Histocytochemistry; Immunohistochemistry; Intestines; Male; NADPH Dehydrogenase; Nitric Oxide; Peripheral Nerves; Rats; Rats, Sprague-Dawley; Tissue Distribution | 1993 |
Mechanism of inhibitory action of ethanol on endothelium-dependent relaxation in rat aorta.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Calcimycin; Cyclic GMP; Endothelium, Vascular; Ethanol; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Nitroprusside; Rats; Rats, Wistar | 1993 |
Effects of calcium channel blockade on the aortic intima in spontaneously hypertensive rats.
Topics: Acetylcholine; Animals; Aorta; Arginine; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Cyclic GMP; Male; Mibefradil; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Rats; Rats, Inbred SHR; Serotonin; Tetrahydronaphthalenes; Thromboxanes; Tunica Intima; Vasoconstriction; Vasodilation | 1993 |
Heparin regulates endothelin production through endothelium-derived nitric oxide in human endothelial cells.
Topics: Analysis of Variance; Arginine; Blotting, Northern; Cells, Cultured; Cyclic GMP; Dactinomycin; Endothelins; Endothelium, Vascular; Heparin; Humans; Kinetics; Nitric Oxide; omega-N-Methylarginine; RNA, Messenger; Thrombin; Time Factors; Umbilical Veins | 1993 |
Nitric oxide. An important signaling mechanism between vascular endothelium and parenchymal cells in the regulation of oxygen consumption.
Topics: 2,4-Dinitrophenol; Animals; Arginine; Bradykinin; Carbachol; Cyclic GMP; Dinitrophenols; Dogs; Endothelium, Vascular; Enzyme Inhibitors; Epoprostenol; Mitochondria, Muscle; Muscle, Skeletal; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Oxygen Consumption; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents | 1995 |
Mechanism of bradykinin-induced cyclic GMP accumulation in bovine tracheal smooth muscle.
Topics: Animals; Arginine; Bradykinin; Calcium; Cattle; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Immunohistochemistry; In Vitro Techniques; Methylene Blue; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Pyrogallol; Superoxide Dismutase; Trachea | 1995 |
3,4-Diaminopyridine-evoked noradrenaline release in rat hippocampal slices: facilitation by endogenous or exogenous nitric oxide.
Topics: 4-Aminopyridine; Amifampridine; Animals; Arginine; Cyclic GMP; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Hemoglobins; Hippocampus; In Vitro Techniques; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Norepinephrine; Perfusion; Rats; Synaptosomes | 1995 |
[Influence of warm ischemia and reperfusion on no-derived cyclic GMP release in the perfused rabbit lung].
Topics: Animals; Arginine; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Ischemia; Lung; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rabbits; Reperfusion | 1995 |
The mechanisms of the renal effects of neutral endopeptidase inhibitor in rats.
Topics: Adrenergic beta-Antagonists; Animals; Arginine; Atrial Natriuretic Factor; Bradykinin; Cyclic GMP; Cyclohexanecarboxylic Acids; Kidney; Kinins; Male; Neprilysin; Nitric Oxide; omega-N-Methylarginine; Protease Inhibitors; Rats; Rats, Sprague-Dawley | 1995 |
The nitric oxide/cGMP system in the antennal lobe of Apis mellifera is implicated in integrative processing of chemosensory stimuli.
Topics: Animals; Arginine; Bees; Brain; Cyclic GMP; Dose-Response Relationship, Drug; NADPH Dehydrogenase; Neural Pathways; Nitric Oxide | 1995 |
Thrombin triggers the de novo expression of an inducible NO synthase in porcine aortic valve endothelial cells.
Topics: Animals; Aorta; Arginine; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Swine; Thrombin | 1995 |
Differential effects of endogenous and exogenous nitric oxide on the release of endothelin-1 from the intact perfused rat adrenal gland in situ.
Topics: Adrenal Glands; Animals; Arginine; Cyclic GMP; Endothelins; Enzyme Inhibitors; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Perfusion; Rats; Rats, Wistar; Second Messenger Systems; Vasodilation | 1996 |
Nitric oxide signaling in ischemic heart.
Topics: Animals; Arginine; Cyclic GMP; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; Perfusion; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Signal Transduction; Superoxide Dismutase | 1995 |
Rolipram increases cyclic GMP content in L-arginine-treated cultured bovine aortic endothelial cells.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Analysis of Variance; Animals; Aorta; Arginine; Cattle; Cells, Cultured; Cyclic AMP; Cyclic GMP; Drug Interactions; Endothelium, Vascular; Exonucleases; Indomethacin; Nitric Oxide; Phosphodiesterase Inhibitors; Pyrrolidinones; Quinolones; Rolipram | 1995 |
Evidence for nitric oxide generation in the cardiomyocytes: its augmentation by hypoxia.
Topics: Acetylcholine; Animals; Arginine; Bradykinin; Cell Hypoxia; Cyclic AMP; Cyclic GMP; Guanidines; Guanylate Cyclase; Heart; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Stimulation, Chemical | 1995 |
Evidence against a role of nitric oxide in the indirect negative inotropic-effect of M-cholinoceptor stimulation in human ventricular myocardium.
Topics: Arginine; Carbachol; Cyclic GMP; Humans; Isoproterenol; Myocardial Contraction; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Papillary Muscles; Receptors, Cholinergic | 1995 |
Excitation of cells in the rostral medial medulla of the rat by the nitric oxide-cyclic guanosine monophosphate messenger system.
Topics: Animals; Arginine; Cyclic GMP; Electrophysiology; Female; Guanosine Monophosphate; Iron; Medulla Oblongata; Methylene Blue; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Rosaniline Dyes; Second Messenger Systems | 1995 |
Comparison of biochemical disturbances in hippocampal slices of gerbil and rat during and after in vitro ischemia.
Topics: Adenosine Triphosphate; Animals; Arginine; Brain Ischemia; Cyclic GMP; Energy Metabolism; Enzyme Inhibitors; Gerbillinae; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; Nitric Oxide Synthase; Nitroarginine; Rats | 1995 |
Chronic L-arginine administration attenuates cardiac hypertrophy in spontaneously hypertensive rats.
Topics: Actins; Animals; Arginine; Base Sequence; Blood Pressure; Bone and Bones; Cardiomegaly; Cyclic GMP; Hemodynamics; Male; Molecular Probes; Molecular Sequence Data; Myocardium; Nitric Oxide; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA, Messenger; Time Factors | 1996 |
Contribution of the nitric oxide-guanylyl cyclase system to circadian regulation of blood pressure in normotensive Wistar-Kyoto rats.
Topics: Animals; Aorta; Arginine; Blood Pressure; Circadian Rhythm; Cyclic GMP; Dose-Response Relationship, Drug; Guanylate Cyclase; Heart Rate; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Rats; Rats, Inbred WKY; Stimulation, Chemical | 1995 |
Nitric oxide-dependent long-term potentiation is blocked by a specific inhibitor of soluble guanylyl cyclase.
Topics: Animals; Arginine; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Lip; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Signal Transduction; Solubility | 1995 |
Endotoxin-induced L-arginine pathway produces nitric oxide and modulates the Ca2+-activated K+ channel in cultured human dermal papilla cells.
Topics: Arginine; Calcium; Cells, Cultured; Cyclic GMP; Endotoxins; Hair Follicle; Humans; NG-Nitroarginine Methyl Ester; Nitric Oxide; Patch-Clamp Techniques; Potassium Channels; Protein Kinases; Skin | 1996 |
Nitric oxide delays the death of trophic factor-deprived PC12 cells and sympathetic neurons by a cGMP-mediated mechanism.
Topics: Adrenergic Fibers; Animals; Arginine; Blood Proteins; Cell Death; Cell Division; Cell Survival; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Nerve Growth Factors; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; PC12 Cells; Phosphodiesterase Inhibitors; Rats | 1996 |
Nitric oxide and ventilatory response to hypoxia.
Topics: Animals; Arginine; Blood Pressure; Carotid Body; Cats; Cyclic GMP; Enzyme Inhibitors; Heart Rate; Hypoxia; Medulla Oblongata; NADPH Dehydrogenase; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Oxygen; Partial Pressure; Rats; Rats, Sprague-Dawley; Respiration; Solitary Nucleus | 1995 |
Cyclic guanosine 3',5' monophosphate concentrations in pre-eclampsia: effects of hydralazine.
Topics: Adult; Arginine; Birth Weight; Blood Pressure; Cyclic GMP; Female; Humans; Hydralazine; Nitric Oxide; Pre-Eclampsia; Pregnancy; Vasodilator Agents | 1996 |
Nitric oxide regulation of glycoconjugate secretion from feline and human airways in vitro.
Topics: Animals; Arginine; Bronchoconstrictor Agents; Cats; Cyclic GMP; Enzyme Inhibitors; Epithelium; Glycoconjugates; Humans; In Vitro Techniques; Methacholine Chloride; NG-Nitroarginine Methyl Ester; Nitric Oxide; Trachea | 1995 |
Evidence that gonadal steroids modulate nitric oxide efflux in the medial preoptic area: effects of N-methyl-D-aspartate and correlation with luteinizing hormone secretion.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arginine; Cyclic GMP; Enzyme Inhibitors; Female; Luteinizing Hormone; Male; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Preoptic Area; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1996 |
Inhibition of ecto-5'-nucleotidase by nitric oxide donors. Implications in renal epithelial cells.
Topics: 5'-Nucleotidase; Animals; Arginine; Biological Transport; Cells, Cultured; Cyclic GMP; Enzyme Inhibitors; Epithelium; Glutathione; Kidney; Kinetics; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Opossums; Phosphates; Rats; Rats, Sprague-Dawley; Sodium | 1996 |
Effects of nitric oxide on detrusor relaxation.
Topics: Animals; Arginine; Cyclic GMP; In Vitro Techniques; Isometric Contraction; Male; Methylene Blue; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Pyrogallol; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Streptozocin; Ultraviolet Rays; Urinary Bladder | 1996 |
Endogenous basal nitric oxide production does not control myocardial oxygen consumption or function.
Topics: Acetylcholine; Analysis of Variance; Animals; Arginine; Biomechanical Phenomena; Coronary Circulation; Cyclic GMP; Dogs; Enzyme Inhibitors; Hemodynamics; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Oxygen Consumption | 1996 |
Halothane and isoflurane inhibit vasodilation due to constitutive but not inducible nitric oxide synthase. Implications for the site of anesthetic inhibition of the nitric oxide/guanylyl cyclase signaling pathway.
Topics: Anesthetics, Inhalation; Animals; Arginine; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Guanylate Cyclase; Halothane; Isoflurane; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Vasodilation | 1996 |
Differential regulation of intracellular signaling systems by sodium fluoride in rat glioma cells.
Topics: Animals; Arginine; Calcium; Chelating Agents; Cyclic GMP; Egtazic Acid; Enzyme Inhibitors; Glioma; omega-N-Methylarginine; Rats; Serotonin; Signal Transduction; Sodium Fluoride; Sulfonamides; Time Factors; Tumor Cells, Cultured; Vasodilator Agents | 1996 |
Evidence that epithelium-derived relaxing factor released by bradykinin in the guinea pig trachea is nitric oxide.
Topics: Adrenergic beta-Antagonists; Animals; Arginine; Bradykinin; Culture Techniques; Cyclic GMP; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelium; Guinea Pigs; Indomethacin; Isomerism; Male; Muscle Contraction; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Trachea | 1996 |
Nitric oxide synthase content of hypothalamic explants: increase by norepinephrine and inactivated by NO and cGMP.
Topics: Animals; Arginine; Carbon Radioisotopes; Citrulline; Cyclic GMP; Gonadotropin-Releasing Hormone; Hypothalamus, Middle; Kinetics; Male; Models, Neurological; Nerve Fibers; Neurons; Nitric Oxide Synthase; Nitroprusside; Norepinephrine; Organ Culture Techniques; Rats; Rats, Wistar | 1996 |
Nitric oxide synthase (NOS3)-mediated cholinergic modulation of Ca2+ current in adult rabbit atrioventricular nodal cells.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Action Potentials; Animals; Arginine; Atrioventricular Node; Calcium Channels; Carbachol; Cyclic GMP; Immunohistochemistry; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rabbits; Receptors, Muscarinic | 1996 |
The insulin-induced increase of guanosine-3',5'-cyclic monophosphate in human platelets is mediated by nitric oxide.
Topics: Adult; Analysis of Variance; Arginine; Blood Platelets; Cyclic GMP; Enzyme Inhibitors; Female; Humans; Insulin; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Recombinant Proteins | 1996 |
Nitric oxide is necessary for a switch from stationary to locomoting phenotype in epithelial cells.
Topics: Animals; Arginine; Base Sequence; Cell Line; Chlorocebus aethiops; Cyclic GMP; Dihydrolipoamide Dehydrogenase; Epithelial Cells; Epithelium; Histocytochemistry; Kidney Tubules; Microscopy, Fluorescence; Molecular Sequence Data; Movement; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oligonucleotides, Antisense; Penicillamine; Phenotype; S-Nitroso-N-Acetylpenicillamine; Thionucleotides | 1996 |
Nitric oxide: a modulator for the epidermal growth factor receptor expression in developing ovarian granulosa cells.
Topics: Animals; Arginine; Cells, Cultured; Cyclic AMP; Cyclic GMP; Diethylstilbestrol; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Female; Follicle Stimulating Hormone; Granulosa Cells; Kinetics; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Rats; Rats, Wistar; Sexual Maturation | 1996 |
Study of NO and VIP as non-adrenergic non-cholinergic neurotransmitters in the pig gastric fundus.
Topics: Animals; Arginine; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Gastric Fundus; Immunohistochemistry; Isotonic Contraction; Male; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Swine; Synaptic Transmission; Vasoactive Intestinal Peptide | 1995 |
Nitric oxide-sensitive and -insensitive contractions of the isolated rabbit iris sphincter muscle.
Topics: Animals; Arginine; Benzoates; Carbachol; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Guanylate Cyclase; Imidazoles; Iris; Male; Methylene Blue; Miotics; Muscle Contraction; Muscle, Smooth; Neurokinin A; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Pupil; Rabbits; Receptors, Cholinergic | 1996 |
Nitric oxide inhibition attenuates systemic hypotension produced by protamine.
Topics: Animals; Arginine; Blood Pressure; Cardiac Output; Cyclic GMP; Dogs; Endothelium, Vascular; Enzyme Inhibitors; Female; Hemodynamics; Heparin; Hypotension; In Vitro Techniques; Male; Methylene Blue; Models, Cardiovascular; Myocardial Contraction; Nitric Oxide; omega-N-Methylarginine; Protamines; Rabbits | 1996 |
Excitotoxicity in the lung: N-methyl-D-aspartate-induced, nitric oxide-dependent, pulmonary edema is attenuated by vasoactive intestinal peptide and by inhibitors of poly(ADP-ribose) polymerase.
Topics: Animals; Arginine; Benzamides; Cyclic GMP; Enzyme Inhibitors; In Vitro Techniques; Lung; Lung Injury; Magnesium; Male; Models, Biological; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Perfusion; Poly(ADP-ribose) Polymerase Inhibitors; Pulmonary Edema; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Vasoactive Intestinal Peptide | 1996 |
Oxidized LDL decreases L-arginine uptake and nitric oxide synthase protein expression in human platelets: relevance of the effect of oxidized LDL on platelet function.
Topics: Arginine; Blood Platelets; Blotting, Western; Cell Survival; Cholesterol; Cyclic GMP; Humans; In Vitro Techniques; Lipoproteins, LDL; Nitric Oxide Synthase; Oxidation-Reduction | 1996 |
Protection against hepatic ischemia/reperfusion injury by exogenous L-arginine.
Topics: Animals; Arginine; Citrulline; Cyclic GMP; Liver; Liver Circulation; Male; Nitrates; Nitric Oxide; Nitrites; Rats; Rats, Wistar; Regional Blood Flow; Reperfusion; Reperfusion Injury | 1996 |
L-arginine can attenuate warm ischemic injury in the rat kidney and nitric oxide production in the preserved kidney.
Topics: Adenosine; Allopurinol; Analysis of Variance; Animals; Arginine; Cyclic GMP; Enzyme Inhibitors; Glutathione; Insulin; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Organ Preservation; Organ Preservation Solutions; Raffinose; Rats; Rats, Wistar; Reperfusion Injury; Temperature | 1996 |
Cytoprotective effect of nitric oxide on ischemia-reperfusion injury in rat kidneys.
Topics: Animals; Arginine; Cyclic GMP; Enzyme Inhibitors; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Organ Preservation; Rats; Rats, Wistar; Reperfusion Injury | 1996 |
Platelet-activating factor augments lipopolysaccharide-induced nitric oxide formation by rat Kupffer cells.
Topics: Animals; Arginine; Biological Transport, Active; Cells, Cultured; Cyclic GMP; Cycloheximide; Dactinomycin; Drug Synergism; Enzyme Induction; Enzyme Inhibitors; Kinetics; Kupffer Cells; Lipopolysaccharides; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Activating Factor; Protein Synthesis Inhibitors; Rats; RNA, Messenger; Shock, Septic | 1996 |
Cyclic GMP regulates activation of phosphoinositidase C by bradykinin in sensory neurons.
Topics: Animals; Arginine; Bradykinin; Cells, Cultured; Cyclic GMP; Dibutyryl Cyclic GMP; Enzyme Activation; Ganglia, Spinal; Inositol 1,4,5-Trisphosphate; Neurons, Afferent; Neuropeptide Y; Nitric Oxide Synthase; Nitroarginine; Phosphoric Diester Hydrolases; Rats | 1996 |
Effects of the nitric oxide synthase inhibitor N omega nitro-L-arginine methyl ester on electrical activity and ion channels of mouse pancreatic B cells.
Topics: Animals; Arginine; Calcium Channels; Cell Membrane; Cyclic GMP; Enzyme Inhibitors; Female; Glucose; In Vitro Techniques; Islets of Langerhans; Membrane Potentials; Mice; Mice, Inbred Strains; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oscillometry; Patch-Clamp Techniques; Potassium Channels | 1996 |
Ginsenosides stimulate endogenous production of nitric oxide in rat kidney.
Topics: Animals; Arginine; Cyclic GMP; Enzyme Inhibitors; Evaluation Studies as Topic; Ginsenosides; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Panax; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Saponins; Stimulation, Chemical | 1996 |
Increased guanylate cyclase activity is associated with an increase in cyclic guanosine 3',5'-monophosphate in left ventricular hypertrophy.
Topics: Animals; Arginine; Cyclic GMP; Dogs; Female; Guanylate Cyclase; Hypertrophy, Left Ventricular; Male; Molsidomine; NG-Nitroarginine Methyl Ester; Oxygen Consumption | 1996 |
Inhibition by triptoquinone-A of LPS- and IL-1 beta-primed induction of NO synthase in rat thoracic aorta.
Topics: Animals; Aorta; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Interleukin-1; Lipopolysaccharides; Male; Medicine, Chinese Traditional; Nitric Oxide Synthase; Rats; Rats, Wistar | 1996 |
Suppression of inducible nitric oxide synthase mRNA expression by tryptoquinone A.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta, Thoracic; Arginine; Base Sequence; Cyclic GMP; Dexamethasone; Diterpenes; DNA Primers; Gene Expression Regulation, Enzymologic; In Vitro Techniques; Interleukin-1; Isoenzymes; Kinetics; Male; Molecular Sequence Data; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitroprusside; Phenylephrine; Plants; Polymerase Chain Reaction; Rats; Rats, Wistar; RNA, Messenger; Time Factors; Transcription, Genetic; Vasodilator Agents | 1996 |
Arginine 75 in the pseudosubstrate sequence of type Ibeta cGMP-dependent protein kinase is critical for autoinhibition, although autophosphorylated serine 63 is outside this sequence.
Topics: Amino Acid Sequence; Animals; Arginine; Cattle; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Molecular Sequence Data; Peptide Mapping; Phosphorylation; Phosphoserine; Structure-Activity Relationship; Substrate Specificity | 1996 |
Cyclic GMP potentiates phenylephrine but not cyclic ADP-ribose-evoked calcium release from rat lacrimal acinar cells.
Topics: Acetylcholine; Adenosine Diphosphate Ribose; Aminoquinolines; Animals; Arginine; Calcium; Cells, Cultured; Cyclic ADP-Ribose; Cyclic GMP; Dibutyryl Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Kinetics; Lacrimal Apparatus; Male; Nitric Oxide Synthase; Nitroarginine; Phenylephrine; Rats; Rats, Wistar | 1996 |
Urinary NO3- excretion as an indicator of nitric oxide formation in vivo during oral administration of L-arginine or L-name in rats.
Topics: Animals; Arginine; Creatinine; Cyclic GMP; Enzyme Inhibitors; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Rats; Rats, Wistar; Time Factors; Urination | 1996 |
Oxytocin-induced penile erection. Role of nitric oxide.
Topics: Animals; Arginine; Cyclic GMP; Enzyme Inhibitors; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Oxytocin; Paraventricular Hypothalamic Nucleus; Penile Erection; Rats; Rats, Sprague-Dawley | 1995 |
Hypotensive mechanisms of amifostine.
Topics: Adrenergic Agents; Amifostine; Animals; Aorta, Thoracic; Arginine; Blood Pressure; Calcium; Cyclic AMP; Cyclic GMP; Ephedrine; Hypotension; In Vitro Techniques; Ligands; Male; Mercaptoethylamines; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Radiation-Protective Agents; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha | 1996 |
Inhibition of NO-medicate responses by 7-ethoxyresorufin, a substrate and competitive inhibitor of cytochrome P450.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Binding, Competitive; Catalase; Cyclic GMP; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Oxazines; Rabbits; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Troleandomycin; Vasodilator Agents | 1996 |
cGMP release in rat mesenteric arterioles and in conduit mesenteric artery.
Topics: Acetylcholine; Animals; Arginine; Arterioles; Cyclic GMP; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Norepinephrine; Rats; Rats, Sprague-Dawley; Vascular Resistance; Vasoconstriction | 1996 |
Temporal relationships between levels of circulating NO derivatives, vascular NO production and hyporeactivity to noradrenaline induced by endotoxin in rats.
Topics: Animals; Arginine; Blood Pressure; Cyclic GMP; In Vitro Techniques; Lipopolysaccharides; Male; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Norepinephrine; Rats; Rats, Wistar; Shock, Septic; Time Factors | 1995 |
Cyclic GMP generation mediated by 5-HT-2 receptors via nitric oxide-dependent pathway and its effect on the desensitization of 5-HT-2 receptors in C6 glioma cells.
Topics: Animals; Arginine; Calcium; Chelating Agents; Cyclic GMP; Dopamine Antagonists; Edetic Acid; Egtazic Acid; Glioma; Haloperidol; Ketanserin; Nitric Oxide; omega-N-Methylarginine; Rats; Receptors, Serotonin; Risperidone; Serotonin Antagonists; Tropanes; Tumor Cells, Cultured | 1995 |
Altered endothelium-dependent responses in lambs with pulmonary hypertension and increased pulmonary blood flow.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Adenosine Triphosphate; Animals; Animals, Newborn; Arginine; Cyclic GMP; Endothelium, Vascular; Hemodynamics; Hypertension, Pulmonary; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Phosphodiesterase Inhibitors; Prostaglandin Endoperoxides, Synthetic; Pulmonary Circulation; Purinones; Sheep; Thromboxane A2; Vasoconstrictor Agents | 1996 |
Excitatory response of rabbit myometrium to nitric oxide in vitro.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Aorta; Arginine; Cyclic GMP; Electric Stimulation; Enzyme Inhibitors; Female; In Vitro Techniques; Indomethacin; Muscle Relaxation; Muscle, Smooth, Vascular; Myometrium; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rabbits; Uterine Contraction | 1996 |
Barium activates rat cerebellar nitric oxide synthase.
Topics: Animals; Arginine; Barium; Calcium; Calmodulin; Cerebellum; Chromatography, Ion Exchange; Citrulline; Cyclic GMP; Enzyme Activation; Lethal Dose 50; Male; Nitric Oxide Synthase; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1996 |
Direct inhibitory effect of thyrotropin-releasing hormone on isolated cecal circular smooth muscle cells of guinea pig.
Topics: Aminoquinolines; Animals; Arginine; Carbachol; Cecum; Cell Size; Cyclic AMP; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone | 1996 |
Effects of LDL on intracellular free calcium and nitric oxide-dependent cGMP formation in porcine endothelial cells.
Topics: Animals; Arginine; Bradykinin; Calcimycin; Calcium; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Ionophores; Lipoproteins, LDL; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Oxidation-Reduction; Swine | 1995 |
Nitric oxide mediates the PAF-stimulated cyclic GMP production in hippocampal slices.
Topics: Animals; Arginine; Cyclic GMP; Dihydropyridines; Enzyme Inhibitors; Hippocampus; In Vitro Techniques; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Platelet Activating Factor; Rats; Rats, Wistar | 1996 |
Effects of L-arginine infusion on renal hemodynamics and sodium excretion during hypo-, normo-, and hyperinsulinemia, as studied in dogs.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arginine; Blood Glucose; Cyclic GMP; Dogs; Glomerular Filtration Rate; Glucose Tolerance Test; Hyperinsulinism; Infusions, Intravenous; Insulin; Renal Circulation; Renal Plasma Flow; Sodium | 1996 |
Systemic and fetal-maternal nitric oxide synthesis in normal pregnancy and pre-eclampsia.
Topics: Adult; Arginine; Blood Platelets; Blotting, Northern; Citrulline; Cyclic GMP; Female; Humans; Nitric Oxide; Nitric Oxide Synthase; Pre-Eclampsia; Pregnancy | 1996 |
Alteration by lipopolysaccharide of the relationship between intracellular calcium levels and contraction in rat mesenteric artery.
Topics: Analysis of Variance; Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Escherichia coli; Lipopolysaccharides; Male; Mesenteric Arteries; Muscle Contraction; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Nitrous Oxide; Norepinephrine; Rats; Vascular Resistance | 1996 |
The 1996 Albert Lasker Medical Research Awards. Signal transduction using nitric oxide and cyclic guanosine monophosphate.
Topics: Animals; Arginine; Awards and Prizes; Cyclic GMP; Enzyme Activation; Enzyme Inhibitors; History, 20th Century; Humans; Isoenzymes; Nitric Oxide; Nitric Oxide Synthase; Prodrugs; Research; Second Messenger Systems; Signal Transduction; United States | 1996 |
[Effect of nitric oxide and cyclic guanosine monophosphate on desensitization of cholinergic neurons in Helix lucorum].
Topics: Aminoquinolines; Animals; Arginine; Cholinergic Antagonists; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Helix, Snails; In Vitro Techniques; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Second Messenger Systems | 1996 |
Endogenous endothelium-derived relaxing factor inhibits platelet adhesion under whole blood flow conditions ex vivo.
Topics: Animals; Arginine; Blood Circulation; Blood Platelets; Blood Pressure; Carbachol; Cyclic AMP; Cyclic GMP; Enzyme Inhibitors; Fibrinogen; Hemoglobins; In Vitro Techniques; Indicators and Reagents; Injections, Intravenous; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Parasympathomimetics; Platelet Adhesiveness; Rats; Rats, Sprague-Dawley | 1995 |
Nitric oxide and cGMP do not affect fluid flux in isolated rat lungs.
Topics: Animals; Arginine; Blood Pressure; Body Fluids; Calcium; Cyclic GMP; Enzyme Inhibitors; Heparin Antagonists; In Vitro Techniques; Ionomycin; Lung; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitrogen Oxides; Organ Size; Protamines; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Spermine | 1996 |
Possible existence of novel endothelium-derived relaxing factor in the endothelium of rat mesenteric arterial bed.
Topics: Acetylcholine; Animals; Arginine; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; In Vitro Techniques; Indoles; Indomethacin; Male; Mesenteric Arteries; Nitric Oxide; Nitroarginine; Octoxynol; Potassium; Rats; Rats, Wistar; Vasodilation; Vasodilator Agents | 1996 |
Is nitric oxide involved in 5-HT2B receptor-mediated contraction in the rat stomach fundus?
Topics: Animals; Arginine; Cyclic GMP; Gastric Fundus; In Vitro Techniques; Male; Muscle Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Wistar; Receptors, Serotonin | 1995 |
L-arginine/nitric oxide pathway activation in platelets of migraine patients with and without aura.
Topics: Adult; Arginine; Blood Platelets; Cyclic GMP; Cytosol; Female; Humans; Male; Migraine Disorders; Nitric Oxide; Platelet Aggregation; Serotonin | 1996 |
Regulation of VIP release from rat enteric nerve terminals: evidence for a stimulatory effect of NO.
Topics: Animals; Arginine; Calcium; Cell Fractionation; Cyclic GMP; Intestine, Small; Membrane Potentials; Molsidomine; NADPH Dehydrogenase; Nerve Endings; Nitric Oxide; Nitroprusside; Protein Kinase C; Rats; Rats, Wistar; Synaptosomes; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 1996 |
Nitric oxide/carbon monoxide. A molecular switch for myocardial preservation during ischemia.
Topics: Animals; Arginine; Bilirubin; Carbon Monoxide; Cyclic GMP; Free Radical Scavengers; Heart; Heme Oxygenase (Decyclizing); Lipid Peroxidation; Male; Myocardial Ischemia; Nitric Oxide; Organ Preservation; Oxidative Stress; Rats; Rats, Sprague-Dawley; Swine | 1996 |
Critical timing of nitric oxide supplementation in cardioplegic arrest and reperfusion.
Topics: Animals; Arginine; Coronary Circulation; Cyclic GMP; Heart Arrest, Induced; L-Lactate Dehydrogenase; Male; Myocardial Contraction; Myocardial Reperfusion Injury; Nitric Oxide; Rats; Rats, Sprague-Dawley; Time Factors | 1996 |
Arginine 210 is not a critical residue for the allosteric interactions mediated by binding of cyclic AMP to site A of regulatory (RIalpha) subunit of cyclic AMP-dependent protein kinase.
Topics: Allosteric Regulation; Allosteric Site; Amino Acid Sequence; Animals; Arginine; Binding Sites; Binding, Competitive; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; DNA Primers; Kinetics; Macromolecular Substances; Mice; Mutagenesis, Site-Directed; Point Mutation; Polymerase Chain Reaction; Recombinant Fusion Proteins; Spectrometry, Fluorescence | 1996 |
Stimulation of nitric oxide-cyclic GMP pathway by L-arginine increases the release of hepatic lipase from cultured rat hepatocytes.
Topics: Alkaloids; Animals; Arginine; Carbazoles; Cyclic GMP; Enzyme Inhibitors; Indoles; Lipase; Liver; Methylene Blue; Nitric Oxide; omega-N-Methylarginine; Protein Kinase Inhibitors; Rats | 1996 |
Evidence for inducible nitric oxide synthase in spontaneously hypertensive rats.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Animals; Aorta, Thoracic; Arginine; Blood Pressure; Cyclic GMP; Enzyme Induction; Guanidines; In Vitro Techniques; Isoenzymes; Lipopolysaccharides; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitrites; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tumor Necrosis Factor-alpha | 1996 |
Effect of L-arginine on myoglobin-induced acute renal failure in the rabbit.
Topics: Acute Kidney Injury; Animals; Arginine; Creatinine; Cyclic GMP; Male; Myoglobin; Nitrates; Nitrites; Rabbits; Renal Circulation; Vascular Resistance | 1996 |
Lubeluzole, a novel long-term neuroprotectant, inhibits the glutamate-activated nitric oxide synthase pathway.
Topics: Animals; Arginine; Cells, Cultured; Cyclic GMP; Glutamic Acid; Guanylate Cyclase; Hippocampus; Interferon-gamma; Lipopolysaccharides; Neuroprotective Agents; Nitric Oxide Synthase; Piperidines; Rats; Stereoisomerism; Thiazoles | 1996 |
Variations in the platelet arginine/nitric oxide pathway during the ovarian cycle in females affected by menstrual migraine.
Topics: Adult; Analysis of Variance; Arginine; Blood Platelets; Collagen; Cyclic GMP; Female; Humans; Menstrual Cycle; Migraine Disorders; Nitric Oxide; Platelet Aggregation | 1996 |
Arginine-modulated receptor-activated calcium influx via a NO/cyclic GMP pathway in human SK-N-SH neuroblastoma cells.
Topics: Arginine; Calcium; Carbachol; Cyclic GMP; Diffusion; Humans; Intracellular Membranes; Muscarinic Agonists; Neuroblastoma; Nitric Oxide; Osmolar Concentration; Receptors, Muscarinic; Tumor Cells, Cultured | 1997 |
Long-term smoking impairs platelet-derived nitric oxide release.
Topics: Adult; Arginine; Blood Platelets; Collagen; Cyclic GMP; Electric Conductivity; Humans; In Vitro Techniques; Male; Membrane Potentials; Nitric Oxide; omega-N-Methylarginine; Penicillamine; Platelet Aggregation; Reference Values; Regression Analysis; S-Nitroso-N-Acetylpenicillamine; Smoking; Vasodilator Agents | 1996 |
Role of cyclic nucleotides in contraction induced by oxytocin in the testicular capsule of the rat in vitro.
Topics: Animals; Arginine; Caffeine; Cyclic AMP; Cyclic GMP; Guanylate Cyclase; Male; omega-N-Methylarginine; Oxytocin; Phosphodiesterase Inhibitors; Rats; Rats, Wistar; Testis; Theophylline | 1996 |
Prophylactic administration of L-arginine improves the intestinal barrier function after mesenteric ischaemia.
Topics: Amino Acids, Essential; Analysis of Variance; Animals; Arginine; Cyclic GMP; Intestinal Mucosa; Male; Mesenteric Arteries; Molsidomine; Nitric Oxide Synthase; Permeability; Polyethylene Glycols; Rats; Rats, Wistar; Reperfusion Injury; Survival Rate; Treatment Outcome; Vasodilator Agents | 1996 |
Apolipoprotein E inhibits platelet aggregation through the L-arginine:nitric oxide pathway. Implications for vascular disease.
Topics: 1-Methyl-3-isobutylxanthine; Apolipoproteins E; Arginine; Blood Platelets; Cholesterol; Cyclic AMP; Cyclic GMP; Dimyristoylphosphatidylcholine; Enzyme Inhibitors; Guanylate Cyclase; Humans; Lipoproteins, HDL; Membrane Lipids; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Phosphodiesterase Inhibitors; Platelet Aggregation; Platelet Aggregation Inhibitors; Quinoxalines | 1997 |
Short-term oral administration of L-arginine reverses defective endothelium-dependent relaxation and cGMP generation in diabetes.
Topics: Acetylcholine; Amino Acids; Animals; Aorta, Thoracic; Arginine; Blood Glucose; Cyclic GMP; Diabetes Mellitus, Experimental; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley | 1996 |
Relationship between insulin resistance and endothelium-dependent vascular relaxation in patients with essential hypertension.
Topics: Arginine; Blood Glucose; Blood Pressure; Cyclic GMP; Female; Heart Rate; Humans; Hypertension; Insulin; Insulin Resistance; Insulin Secretion; Male; Middle Aged; Renal Circulation; Vasodilation | 1997 |
Diabetes and insulin-induced stimulation of L-arginine transport and nitric oxide synthesis in rabbit isolated gastric glands.
Topics: Animals; Arginine; Citrulline; Cyclic GMP; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Exocrine Glands; Gastric Mucosa; Hypoglycemic Agents; Insulin; Kinetics; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rabbits | 1997 |
Involvement of glibenclamide-sensitive potassium channels in vasorelaxation by cochlear nerve stimulation.
Topics: Animals; Aorta; Arginine; Cochlea; Cochlear Nerve; Cyclic AMP; Cyclic GMP; Electric Stimulation; Endothelium, Vascular; Enzyme Inhibitors; Glyburide; Guinea Pigs; Male; Neurotoxins; Neurotransmitter Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Potassium Channels; Rabbits; Tetrodotoxin; Vasodilation; Vasodilator Agents | 1997 |
Inhalational anesthetic effects on rat cerebellar nitric oxide and cyclic guanosine monophosphate production.
Topics: Anesthetics, Inhalation; Animals; Arginine; Cerebellum; Citrulline; Cyclic GMP; Drug Interactions; Excitatory Amino Acid Agonists; Halothane; Isoflurane; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Tritium | 1997 |
Biochemical evidence for impaired nitric oxide synthesis in patients with peripheral arterial occlusive disease.
Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Arterial Occlusive Diseases; Cyclic GMP; Disease Progression; Enzyme Inhibitors; Female; Humans; Male; Middle Aged; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Peripheral Vascular Diseases; Vasodilation | 1997 |
Inhibition of cerebellar nitric oxide synthase and cyclic GMP production by melatonin via complex formation with calmodulin.
Topics: Animals; Arginine; Calmodulin; Cerebellum; Citrulline; Cyclic GMP; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Kinetics; Male; Melatonin; Nitric Oxide Synthase; Rats; Rats, Wistar | 1997 |
Dietary L-arginine supplementation normalizes regional blood flow in Dahl-Iwai salt-sensitive rats.
Topics: Albuminuria; Animals; Arginine; Blood Circulation; Cyclic GMP; Diet; Drug Resistance; Hemodynamics; Hypertension; Male; Microspheres; Proteinuria; Rats; Rats, Inbred Strains; Regional Blood Flow; Sodium Chloride | 1997 |
Agmatine affects glomerular filtration via a nitric oxide synthase-dependent mechanism.
Topics: Agmatine; Animals; Arginine; Cyclic GMP; Enzyme Activation; Enzyme Inhibitors; Glomerular Filtration Rate; Nitric Oxide Synthase; omega-N-Methylarginine; Perfusion; Rats; Receptors, Adrenergic, alpha-2; Signal Transduction | 1997 |
Nitric oxide and excitatory postsynaptic currents in immature rat sympathetic preganglionic neurons in vitro.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Cyclic GMP; Electric Stimulation; Evoked Potentials; Ganglia, Sympathetic; Hemoglobins; Immunohistochemistry; Nerve Fibers; Neurons; Nitric Oxide Synthase; Nitroarginine; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Spinal Cord; Synaptic Transmission | 1997 |
Opposite effects of nitric oxide on identified inhibitory and excitatory cholinergic synapses of Aplysia californica.
Topics: Acetylcholine; Action Potentials; Animals; Aplysia; Arginine; Calcium Channels; Cholinergic Agonists; Cholinergic Antagonists; Cyclic GMP; Ganglia, Invertebrate; Ganglia, Parasympathetic; Guanylate Cyclase; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; Potassium Channels; Synapses; Synaptic Transmission | 1996 |
Characteristics of coronary endothelial dysfunction in experimental diabetes.
Topics: Acetylcholine; Animals; Arginine; Coronary Circulation; Coronary Vessels; Cyclic GMP; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimental; Dogs; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Ibuprofen; In Vitro Techniques; Indomethacin; Male; Nitric Oxide; Nitroprusside; Vasodilation; Vasodilator Agents | 1997 |
Role of exogenous L-arginine in hepatic ischemia-reperfusion injury.
Topics: Animals; Arginine; Aspartate Aminotransferases; Blood Pressure; Citrulline; Cyclic GMP; Female; Hemodynamics; Liver; Male; Nitrates; Nitric Oxide; Nitrites; Rats; Rats, Wistar; Reperfusion Injury; Swine; Time Factors | 1997 |
Endogenously produced nitric oxide increases tumor necrosis factor-alpha production in transfected human U937 cells.
Topics: Animals; Arginine; Cell Differentiation; Citrulline; Cyclic GMP; DNA, Complementary; Enzyme Induction; Gene Expression Regulation, Neoplastic; Genetic Vectors; Humans; Lymphoma, Large B-Cell, Diffuse; Mice; Neoplasm Proteins; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Recombinant Fusion Proteins; Second Messenger Systems; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1997 |
Aging and severity of hypertension attenuate endothelium-dependent renal vascular relaxation in humans.
Topics: Adult; Aged; Aging; Arginine; Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Endothelium, Vascular; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Osmolar Concentration; Renal Circulation; Vasodilation | 1997 |
[L-arginine nitric oxide pathway in acute renal ischemia reperfusion injury of the aged rats].
Topics: Aging; Animals; Arginine; Cyclic GMP; Ischemia; Kidney; Male; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Renal Agents; Reperfusion Injury | 1996 |
Nitric oxide and cGMP regulate endothelial permeability and F-actin distribution in hydrogen peroxide-treated endothelial cells.
Topics: Actin Cytoskeleton; Actins; Animals; Aorta; Arginine; Cattle; Cell Membrane Permeability; Cells, Cultured; Cyclic GMP; Dextrans; Endothelium, Vascular; Fluorescein; Fluorescein-5-isothiocyanate; Fluoresceins; Fluorescent Dyes; Hydrogen Peroxide; Kinetics; NG-Nitroarginine Methyl Ester; Nitric Oxide | 1997 |
Dietary L-arginine reduces the progression of atherosclerosis in cholesterol-fed rabbits: comparison with lovastatin.
Topics: Animals; Anticholesteremic Agents; Arginine; Arteriosclerosis; Cholesterol; Cholesterol, Dietary; Cyclic GMP; Diet, Atherogenic; Endothelium, Vascular; Hypercholesterolemia; Lovastatin; Male; Nitrates; Nitric Oxide; Rabbits; Superoxides | 1997 |
Tetrahydrobiopterin regulates cyclic GMP-dependent electrogenic Cl- secretion in mouse ileum in vitro.
Topics: Animals; Antioxidants; Arginine; Biopterins; Carbachol; Chloride Channels; Cholinergic Agonists; Cyclic GMP; Ileum; In Vitro Techniques; Intestinal Mucosa; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Muscle, Smooth; Nitric Oxide; Nitrites; Time Factors | 1997 |
Prolonged reduction of high blood pressure with human nitric oxide synthase gene delivery.
Topics: Animals; Arginine; Blood Pressure; Cattle; Cell Line; Cyclic GMP; Cytomegalovirus; DNA; Endothelium, Vascular; Genetic Therapy; Humans; Hypertension; Male; Nitric Oxide Synthase; Promoter Regions, Genetic; Pulmonary Artery; Rats; Rats, Inbred SHR; Time Factors; Transfection | 1997 |
Excitatory effects of nitric oxide within the rostral ventrolateral medulla of freely moving rats.
Topics: Animals; Arginine; Cyclic GMP; Glutamic Acid; Male; Medulla Oblongata; Microinjections; Nitric Oxide; Penicillamine; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine | 1997 |
Plasma and vascular tissue arginine are decreased in diabetes: acute arginine supplementation restores endothelium-dependent relaxation by augmenting cGMP production.
Topics: Animals; Arginine; Body Weight; Cyclic GMP; Diabetes Mellitus, Experimental; Endothelium, Vascular; Male; Nitric Oxide; Rats; Rats, Sprague-Dawley; Streptozocin; Vasodilation | 1997 |
Actions of compounds manipulating the nitric oxide system in the cat primary visual cortex.
Topics: Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arginine; Cats; Cyclic GMP; Electrophysiology; Enzyme Inhibitors; Excitatory Amino Acids; Hydrazines; Iontophoresis; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitrogen Oxides; Visual Cortex | 1997 |
Effect of long-term oral L-arginine on the nitric oxide synthase pathway in the urine from patients with interstitial cystitis.
Topics: Administration, Oral; Arginine; Cyclic GMP; Cystitis, Interstitial; Female; Humans; Nitrates; Nitric Oxide Synthase; Nitrites; Time Factors | 1997 |
Role of endothelin, nitric oxide and L-arginine release in ischaemia/reperfusion injury of rat heart.
Topics: Analysis of Variance; Animals; Arginine; Chromatography, High Pressure Liquid; Cyclic GMP; Endothelin Receptor Antagonists; Endothelin-1; L-Lactate Dehydrogenase; Myocardial Reperfusion Injury; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Oligopeptides; Penicillamine; Perfusion; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents | 1997 |
Nitric oxide signaling mediates stimulation of L-type Ca2+ current elicited by withdrawal of acetylcholine in cat atrial myocytes.
Topics: Acetylcholine; Animals; Arginine; Calcium Channels; Calmodulin; Cats; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Electrophysiology; Enzyme Activation; Enzyme Inhibitors; Female; Guanylate Cyclase; Heart Atria; Hemoglobins; Histocytochemistry; Isoquinolines; Male; Muscle Fibers, Skeletal; Myocardium; Nitric Oxide; Pertussis Toxin; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Signal Transduction; Spermine; Sulfonamides; Virulence Factors, Bordetella | 1998 |
Inducible nitric oxide synthase augments injury elicited by oxidative stress in rat cardiac myocytes.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Animals, Newborn; Arginine; Cells, Cultured; Cyclic GMP; Enzyme Induction; Glutathione Peroxidase; Heart; Heart Injuries; Kinetics; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Oligonucleotides, Antisense; Oxidative Stress; Penicillamine; Rats; S-Nitroso-N-Acetylpenicillamine | 1998 |
A state-independent interaction between ligand and a conserved arginine residue in cyclic nucleotide-gated channels reveals a functional polarity of the cyclic nucleotide binding site.
Topics: Amino Acid Sequence; Animals; Arginine; Binding Sites; Conserved Sequence; Cyclic AMP; Cyclic GMP; Ion Channel Gating; Ion Channels; Molecular Sequence Data; Mutagenesis, Site-Directed; Patch-Clamp Techniques; Xenopus | 1998 |
Arginine in burn injury improves cardiac performance and prevents bacterial translocation.
Topics: Animals; Arginine; Bacterial Translocation; Burns; Coronary Circulation; Cyclic GMP; Fluid Therapy; Hemodynamics; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Resuscitation; Stereoisomerism; Ventricular Function | 1998 |
Elevated D-glucose induces insulin insensitivity in human umbilical endothelial cells isolated from gestational diabetic pregnancies.
Topics: Amino Acids; Antimetabolites; Arginine; Calcium; Citrulline; Cyclic GMP; Deoxyglucose; Endothelium, Vascular; Epoprostenol; Female; Glucose; Humans; Insulin Resistance; Membrane Potentials; Onium Compounds; Organophosphorus Compounds; Pregnancy; Pregnancy in Diabetics; Umbilical Veins | 1998 |
Neuronal NOS-cGMP-dependent ACh-induced relaxation in pial arterioles of endothelial NOS knockout mice.
Topics: Acetylcholine; Animals; Arginine; Arterioles; Autoradiography; Brain; Citrulline; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Indazoles; Mice; Mice, Knockout; Neurons; Nitric Oxide Synthase; Pia Mater; Quinuclidinyl Benzilate; Receptors, Muscarinic; Vasodilation | 1998 |
L-arginine prevents lung neutrophil accumulation and preserves pulmonary endothelial function after endotoxin.
Topics: Acetylcholine; Animals; Arginine; Bacterial Toxins; Calcimycin; Cyclic GMP; Endothelium; Endotoxins; Ionophores; Lung; Male; Muscle, Smooth, Vascular; Neutrophils; Nitroprusside; Peroxidase; Rats; Rats, Sprague-Dawley; Vasodilation; Vasodilator Agents | 1998 |
Evidence that spontaneous contractile activity in the rat myometrium is not inhibited by NO-mediated increases in tissue levels of cyclic GMP.
Topics: Animals; Arginine; Atrial Natriuretic Factor; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Female; In Vitro Techniques; Muscle Relaxation; Myometrium; Nitric Oxide; Nitroprusside; Penicillamine; Pregnancy; Rats; Rats, Sprague-Dawley; Uterine Contraction | 1998 |
H2O2 causes endothelial barrier dysfunction without disrupting the arginine-nitric oxide pathway.
Topics: Animals; Arginine; Capillary Permeability; Cells, Cultured; Citrulline; Cyclic GMP; Endothelium, Vascular; Hydrogen Peroxide; Nitric Oxide; Nitric Oxide Synthase; Oxidants; Pulmonary Artery; Swine | 1998 |
L-arginine, a nitric oxide precursor, attenuates ischemia-reperfusion injury by inhibiting inositol-1,4,5-triphosphate.
Topics: Animals; Arginine; Calcium; Cyclic GMP; Down-Regulation; Inositol 1,4,5-Trisphosphate; Male; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; Perfusion; Premedication; Rats; Rats, Sprague-Dawley; Time Factors; Ventricular Function, Left | 1998 |
Nitric oxide synthase modulates angiogenesis in response to tissue ischemia.
Topics: Animals; Arginine; Cyclic GMP; Endothelial Growth Factors; Hemodynamics; Iliac Artery; Ischemia; Lymphokines; Male; Mice; Mice, Inbred C57BL; Neovascularization, Physiologic; Nitric Oxide Synthase; Rabbits; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1998 |
Increased aggregation of human platelets produced by advanced glycation end products in vitro.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Arginine; Arteriosclerosis; Cyclic AMP; Cyclic GMP; Female; Glycation End Products, Advanced; Humans; Indomethacin; Lysine; Male; Oxidative Stress; Platelet Aggregation; Polylysine; Prostaglandins; Reactive Oxygen Species; Serum Albumin, Bovine; Superoxide Dismutase; Superoxides | 1998 |
Factors contributing to differences in the regulation of cGMP in isolated porcine pulmonary vessels.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Blotting, Western; Carbon Radioisotopes; Citrulline; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Female; Guanylate Cyclase; Male; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Pulmonary Veins; Purinones; Swine | 1998 |
Chronic L-arginine treatment increases cardiac cyclic guanosine 5'-monophosphate in rats with aortic stenosis: effects on left ventricular mass and beta-adrenergic contractile reserve.
Topics: Adrenergic beta-Agonists; Animals; Aortic Valve Stenosis; Arginine; Blood Pressure; Calcium; Case-Control Studies; Cyclic GMP; Hypertension; Hypertrophy, Left Ventricular; Isoproterenol; Longitudinal Studies; Male; Myocardial Contraction; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Random Allocation; Rats; Rats, Wistar; Signal Transduction; Systole; Ventricular Function, Left; Ventricular Pressure | 1998 |
Molecular cloning and expression of inducible nitric oxide synthase in chick embryonic ventricular myocytes.
Topics: Amino Acid Sequence; Animals; Arginine; Blotting, Northern; Calcium; Cell Size; Chick Embryo; Cloning, Molecular; Conserved Sequence; Cyclic GMP; Enzyme Inhibitors; Gene Expression; Humans; Lipopolysaccharides; Molecular Sequence Data; Myocardial Contraction; Myocardium; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; RNA, Messenger; Sequence Homology, Amino Acid | 1998 |
Nonadrenergic, noncholinergic relaxation mediated by nitric oxide with concomitant change in Ca2+ level in rectal circular muscle of rats.
Topics: Animals; Arginine; Calcium; Cyclic GMP; Electric Stimulation; Immunohistochemistry; In Vitro Techniques; Male; Membrane Potentials; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Myenteric Plexus; Neuropeptides; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Peptide Fragments; Pituitary Adenylate Cyclase-Activating Polypeptide; Potassium Channel Blockers; Rats; Rats, Wistar; Rectum; Vasoactive Intestinal Peptide | 1998 |
Effects of antisense oligonucleotide to iNOS on hemodynamic and vascular changes induced by LPS.
Topics: Animals; Aorta; Arginine; Citrulline; Cyclic GMP; Enzyme Inhibitors; Hemodynamics; Lipopolysaccharides; Lung; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Norepinephrine; Oligonucleotides, Antisense; Rats; Rats, Wistar; RNA, Messenger | 1998 |
The negative inotropic effect of beta3-adrenoceptor stimulation is mediated by activation of a nitric oxide synthase pathway in human ventricle.
Topics: Adrenergic beta-Agonists; Arginine; Cyclic GMP; Ethanolamines; Female; Heart; Heart Ventricles; Humans; Isoproterenol; Kinetics; Male; Middle Aged; Myocardial Contraction; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroarginine; Norepinephrine; omega-N-Methylarginine; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3 | 1998 |
Arginine availability controls the N-methyl-D-aspartate-induced nitric oxide synthesis: involvement of a glial-neuronal arginine transfer.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Arginine; Cerebellum; Cerebral Cortex; Cyclic GMP; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; In Vitro Techniques; N-Methylaspartate; Neuroglia; Neurons; Nitric Oxide; Nitroarginine; Rats; Rats, Inbred Strains | 1998 |
Endogenous asymmetrical dimethylarginine and hypertension associated with puromycin nephrosis in the rat.
Topics: Animals; Arginine; Blood Pressure; Body Weight; Cyclic GMP; Endothelium; Glomerulosclerosis, Focal Segmental; Hypertension; Kidney; Male; Nitrous Oxide; Puromycin Aminonucleoside; Rats; Rats, Sprague-Dawley | 1998 |
[Effect of nitric oxide on rabbit baroreceptor activity].
Topics: Animals; Arginine; Carotid Sinus; Cyclic GMP; Female; In Vitro Techniques; Male; Nitric Oxide; Nitroglycerin; Pressoreceptors; Rabbits; Vasodilator Agents | 1997 |
Exhaled oral and nasal nitric oxide during L-arginine infusion in preeclampsia.
Topics: Adult; Arginine; Blood Pressure; Breath Tests; Cyclic GMP; Female; Heart Rate; Humans; Luminescent Measurements; Mouth; Nitrates; Nitric Oxide; Nose; Pre-Eclampsia; Pregnancy | 1998 |
Role of nitric oxide in cyclosporine A-induced hypertension.
Topics: Animals; Aorta; Arginine; Blood Pressure; Bosentan; Cyclic GMP; Cyclosporine; Endothelin Receptor Antagonists; Enzyme Inhibitors; Hypertension; Immunosuppressive Agents; Male; Nitrates; Nitrites; Olive Oil; Penicillamine; Peptides, Cyclic; Plant Oils; Rats; Rats, Sprague-Dawley; Sulfonamides; Vasoconstriction | 1998 |
Progesterone enhances prostaglandin E2 production via interaction with nitric oxide in the mouse acrosome reaction.
Topics: Acrosome Reaction; Animals; Arginine; Citrulline; Cyclic GMP; Dinoprostone; Enzyme Inhibitors; Exocytosis; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Progesterone; Spermatozoa | 1998 |
Escherichia coli lipopolysaccharide downregulates soluble guanylate cyclase in pulmonary artery smooth muscle.
Topics: Animals; Arginine; Cells, Cultured; Cyclic GMP; Down-Regulation; Enzyme Inhibitors; Escherichia coli; Guanylate Cyclase; Lipopolysaccharides; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Pulmonary Artery; Rats; RNA, Messenger | 1998 |
Role of nitric oxide and cGMP in human septic serum-induced depression of cardiac myocyte contractility.
Topics: Animals; Arginine; Blood Physiological Phenomena; Cyclic GMP; Drug Combinations; Enzyme Inhibitors; Humans; Interleukin-1; Methylene Blue; Myocardial Contraction; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nucleotides, Cyclic; omega-N-Methylarginine; Rats; Shock, Septic; Tumor Necrosis Factor-alpha | 1999 |
L-arginine attenuates endothelial dysfunction in endotoxin-induced lung injury.
Topics: Acetylcholine; Animals; Arginine; Calcimycin; Cyclic GMP; Endothelium, Vascular; Endotoxins; In Vitro Techniques; Lung; Lung Injury; Male; Nitric Oxide; Nitroprusside; Phenylephrine; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Salmonella typhimurium; Stereoisomerism; Vasoconstriction; Vasodilation | 1999 |
Exogenous nitric oxide inhibits platelet activation in whole blood.
Topics: Arginine; Blood Coagulation; Blood Platelets; Collagen; Cyclic GMP; Humans; In Vitro Techniques; Isosorbide Dinitrate; Nitric Oxide; Nitroprusside; P-Selectin; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Vasodilator Agents; Whole Blood Coagulation Time | 1999 |
Compartmentalization of extracellular cGMP determines absorptive or secretory responses in the rat jejunum.
Topics: Angiotensin II; Animals; Arginine; Chlorides; Cyclic GMP; Diet, Sodium-Restricted; Enterotoxins; Imidazoles; Intestinal Absorption; Jejunum; Male; Microscopy, Fluorescence; NG-Nitroarginine Methyl Ester; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Sodium; Water | 1999 |
Nitric oxide stimulates cyclic guanosine monophosphate production and electrogenic secretion in Caco-2 colonocytes.
Topics: Arginine; Caco-2 Cells; Cyclic GMP; Cystamine; Enzyme Inhibitors; Humans; Inflammatory Bowel Diseases; Intestinal Mucosa; Ion Transport; Isomerism; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrites; Nitroprusside | 1999 |
cGMP production is coupled to Ca(2+)-dependent nitric oxide generation in rabbit parotid acinar cells.
Topics: Aminoquinolines; Animals; Arginine; Calcimycin; Calcium; Citrulline; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Methacholine Chloride; Models, Biological; NG-Nitroarginine Methyl Ester; Nitric Oxide; Parotid Gland; Rabbits; Receptors, Muscarinic; Thapsigargin; Time Factors | 1998 |
Accelerated intimal hyperplasia and increased endogenous inhibitors for NO synthesis in rabbits with alloxan-induced hyperglycaemia.
Topics: Alloxan; Animals; Arginine; Blood Glucose; Body Weight; Carotid Arteries; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Hyperglycemia; Hyperplasia; In Vitro Techniques; Male; Nitric Oxide; omega-N-Methylarginine; Rabbits; Tunica Intima; Tunica Media; Weight Gain | 1999 |
Selective stimulation of L-arginine uptake contributes to shear stress-induced formation of nitric oxide.
Topics: Adenosine Diphosphate; Animals; Aorta; Arginine; Biological Transport; Bradykinin; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Kinetics; Leucine; Nitric Oxide; Stress, Mechanical; Superoxide Dismutase; Swine; Thapsigargin | 1999 |
Renal vasoconstriction induced by oxidized LDL is inhibited by scavengers of reactive oxygen species and L-arginine.
Topics: Animals; Arginine; Catalase; Cyclic GMP; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Free Radical Scavengers; Glomerular Filtration Rate; Indomethacin; Lipoproteins, LDL; Male; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Renal Artery; Superoxide Dismutase; Vasoconstriction | 1999 |
Regression of atherosclerosis: role of nitric oxide and apoptosis.
Topics: Animals; Aorta, Abdominal; Apoptosis; Arginine; Arteriosclerosis; Cyclic GMP; Dietary Supplements; Male; Nitric Oxide; Nitric Oxide Synthase; Organ Culture Techniques; Rabbits | 1999 |
Effects of halothane on renal hemodynamics and interstitial nitric oxide in rabbits.
Topics: Anesthetics, Inhalation; Animals; Arginine; Blood Pressure; Cyclic GMP; Dose-Response Relationship, Drug; Drug Interactions; Guanylate Cyclase; Halothane; Kidney; Male; Microdialysis; Nitric Oxide; Nitroprusside; Rabbits; Renal Circulation; Vasoconstriction | 1999 |
Intracellular polyamine levels are involved in NMDA-evoked nitric oxide production in chick retina cells.
Topics: Animals; Arginine; Cells, Cultured; Chick Embryo; Citrulline; Cyclic GMP; Eflornithine; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glycine; N-Methylaspartate; NADPH Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase; Polyamines; Receptors, N-Methyl-D-Aspartate; Retina; Spermidine | 1999 |
Nitric oxide metabolites, cyclic guanosine 3,5 monophosphate and dimethylarginines during and after uncomplicated pregnancies: a longitudinal study.
Topics: Adult; Arginine; Chromatography, High Pressure Liquid; Creatinine; Cyclic GMP; Enzyme Inhibitors; Ethylenediamines; Female; Free Radical Scavengers; Humans; Immunoenzyme Techniques; Longitudinal Studies; Male; Nitrates; Nitric Oxide; Nitrites; Postpartum Period; Pregnancy; Reference Values; Sulfanilamides; Time Factors | 1999 |
A comparative study of the effects of nitric oxide and carbon monoxide on the in vivo release of gonadotropin-releasing hormone and neuropeptide Y from rat hypothalamus during the estradiol-induced luteinizing hormone surge: estimation by push-pull perfus
Topics: Animals; Arcuate Nucleus of Hypothalamus; Arginine; Carbon Monoxide; Catheterization; Circadian Rhythm; Cyclic GMP; Estradiol; Female; Gonadotropin-Releasing Hormone; Hypothalamus; Luteinizing Hormone; Median Eminence; Neuropeptide Y; Nitric Oxide; Preoptic Area; Rats; Rats, Wistar | 1999 |
Modulation of human platelet function by L-canavanine: differential effects of low and high concentrations.
Topics: Adenosine Diphosphate; Arginine; Blood Platelets; Canavanine; Catecholamines; Cyclic GMP; Drug Interactions; Humans; In Vitro Techniques; Nitric Oxide Synthase; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Serotonin | 1999 |
[Effect of L-arg and LNNA on contractile-relaxant response and cGMP level of thoracic aorta with endothelial injury in rat].
Topics: Animals; Aorta, Thoracic; Arginine; Cyclic GMP; Endothelium, Vascular; Male; Nitric Oxide; Nitroarginine; Rats; Rats, Wistar; Vasodilation | 1997 |
Nitric oxide production is low in end-stage renal disease patients on peritoneal dialysis.
Topics: Adult; Aged; Arginine; Citrulline; Creatinine; Cyclic GMP; Female; Humans; Hypertension, Renal; Kidney; Kidney Failure, Chronic; Male; Middle Aged; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Oxidation-Reduction; Peritoneal Dialysis | 1999 |
L-arginine limits myocardial cell death secondary to hypoxia-reoxygenation by a cGMP-dependent mechanism.
Topics: Animals; Arginine; Cell Death; Cells, Cultured; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Hypoxia; L-Lactate Dehydrogenase; Male; Muscle Fibers, Skeletal; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; Oxadiazoles; Oxygen Consumption; Quinoxalines; Rats; Rats, Sprague-Dawley | 1999 |
Nitric oxide via cGMP-dependent mechanisms increases dye coupling and excitability of rat supraoptic nucleus neurons.
Topics: Animals; Arginine; Cyclic GMP; Female; Fluorescent Dyes; Guanylate Cyclase; In Vitro Techniques; Isoquinolines; Male; Membrane Potentials; Neurons; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Rats; Rats, Sprague-Dawley; Supraoptic Nucleus | 1999 |
NO releases bombesin-like immunoreactivity from enteric synaptosomes by cross-activation of protein kinase A.
Topics: Animals; Arginine; Bombesin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Intestine, Small; Male; Nitric Oxide; Nitric Oxide Donors; Nitroarginine; Oxadiazoles; Phosphodiesterase Inhibitors; Protein Kinase Inhibitors; Purinones; Quinoxalines; Rats; Rats, Wistar; Synaptosomes | 1999 |
Enhanced nitric oxide synthesis reverses salt-induced alterations in blood flow and cGMP levels.
Topics: Animals; Aorta, Abdominal; Arginine; Blood Flow Velocity; Blood Pressure; Cyclic GMP; Eicosapentaenoic Acid; Enzyme Inhibitors; Heart Rate; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Radioimmunoassay; Random Allocation; Rats; Rats, Inbred Dahl; Renal Artery; Sodium, Dietary | 1999 |
Cyclooxygenase inhibition converts the effect of nitric oxide synthase inhibition from infarct size reduction to expansion in isolated rabbit hearts.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arginine; Cyclic GMP; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Hemodynamics; In Vitro Techniques; Indomethacin; Male; Myocardial Infarction; Myocardial Reperfusion; Nitric Oxide Synthase; Nitroarginine; Rabbits | 1999 |
Possible involvement of nitroglycerin converting step in nitroglycerin tolerance.
Topics: Animals; Aorta, Thoracic; Arginine; Cyclic GMP; Drug Tolerance; In Vitro Techniques; Lipopolysaccharides; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Donors; Nitroarginine; Nitroglycerin; Nitroprusside; Rats; Rats, Wistar; Vasodilation | 1999 |
Intracerebroventricularly injected L-arginine-induced vasopressin release is mediated by cGMP in rats.
Topics: Animals; Arginine; Arginine Vasopressin; Cyclic GMP; Guanylate Cyclase; Injections, Intraventricular; Male; Methylene Blue; Rats; Rats, Sprague-Dawley | 1998 |
L-arginine inhibits ischemia-reperfusion lung injury in rabbits.
Topics: Animals; Arginine; Body Fluids; Capillary Permeability; Cyclic GMP; Enzyme Inhibitors; Hemodynamics; In Vitro Techniques; Ischemia; Lung; Nitroarginine; Pressure; Pulmonary Circulation; Rabbits; Reperfusion Injury; Trachea; Vascular Resistance | 1999 |
Effects of L-arginine in rat adrenal cells: involvement of nitric oxide synthase.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenocorticotropic Hormone; Animals; Arginine; Corticosterone; Cyclic GMP; Drug Synergism; Enzyme Inhibitors; Hydroxycholesterols; Lysine; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Ornithine; Pregnenolone; Rats; Rats, Wistar; Zona Fasciculata | 1999 |
No detectable NO synthesis from L-arginine or N(G)-hydroxy-L-arginine in fMLP-stimulated human blood neutrophils despite production of nitrite, nitrate, and citrulline from N(G)-hydroxy-L-arginine.
Topics: Arginine; Cells, Cultured; Citrulline; Cyclic GMP; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitrates; Nitric Oxide; Nitrites; Nitroarginine | 1999 |
Release of nitric oxide within the coeliac plexus is involved in the organization of a gastroduodenal inhibitory reflex in the rabbit.
Topics: Action Potentials; Animals; Arginine; Benzoates; Celiac Plexus; Cyclic GMP; Duodenum; Enzyme Inhibitors; Female; Gastrointestinal Motility; Imidazoles; Male; Muscle, Smooth; Nitric Oxide; Nitroarginine; Oxadiazoles; Quinoxalines; Rabbits; Reflex; Stomach | 1999 |
Central control of blood pressure by nitrergic mechanisms in organum vasculosum laminae terminalis of rat brain.
Topics: Animals; Arginine; Blood Pressure; Brain; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Hydroxylamine; Male; Methylene Blue; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Rats; Rats, Sprague-Dawley; Sodium Azide; Spinal Cord Injuries | 1999 |
The role of systemic, spinal and supraspinal L-arginine-nitric oxide-cGMP pathway in thermal hyperalgesia caused by intrathecal injection of glutamate in mice.
Topics: Analysis of Variance; Animals; Arginine; Cyclic GMP; Enzyme Inhibitors; Glutamic Acid; Hot Temperature; Hyperalgesia; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Spinal; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine | 1999 |
Inhibition of excitatory neurotransmitter-nitric oxide signaling pathway by inhalational anesthetics.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Inhalation; Animals; Arginine; Cells, Cultured; Cerebral Cortex; Cyclic GMP; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Guanylate Cyclase; Halothane; Isoflurane; Kainic Acid; N-Methylaspartate; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitroprusside; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Signal Transduction | 1999 |
Reduced nitric oxide production by L-arginine deficiency in lysinuric protein intolerance exacerbates intravascular coagulation.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Antithrombin III; Arginine; Blood Coagulation Disorders; Citrulline; Cyclic GMP; Humans; Lysine; Male; Nitric Oxide; Nitroglycerin; Ornithine; Peptide Hydrolases; Platelet Aggregation; Thrombosis | 1999 |
Hepatocyte growth factor regulates human trophoblast motility and invasion: a role for nitric oxide.
Topics: Arginine; Cell Division; Cell Line; Cell Movement; Cell Size; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Induction; Female; Fibrin; Hepatocyte Growth Factor; Humans; Integrins; Interleukin-1; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; RNA, Messenger; Transfection; Trophoblasts; Tumor Necrosis Factor-alpha | 1999 |
Effects of L-arginine on the afferent resting activity in the cephalopod statocyst.
Topics: Action Potentials; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Arginine; Cyclic AMP; Cyclic GMP; Cystamine; DDT; Decapodiformes; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Guanylate Cyclase; Hair Cells, Vestibular; Imines; Immunosuppressive Agents; Male; Methylene Blue; Mollusca; NADP; NG-Nitroarginine Methyl Ester; Niacin; Nitric Oxide; Nitroarginine; Oxadiazoles; Postural Balance; Quinoxalines; Sodium Chloride | 1999 |
Effects of L-arginine on cyclosporin-induced alterations of vascular NO/cGMP generation.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Cyclic GMP; Cyclosporine; In Vitro Techniques; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroprusside; Rats; Rats, Sprague-Dawley; Vasodilation; Vasodilator Agents | 1999 |
Amniotic fluid nitric oxide metabolites, cyclic guanosine 3',5' monophosphate and dimethylarginine in alloimmunized pregnancies.
Topics: Amniocentesis; Amniotic Fluid; Arginine; Blood Transfusion, Intrauterine; Creatinine; Cyclic GMP; Embryonic and Fetal Development; Erythroblastosis, Fetal; Female; Gestational Age; Humans; Infant, Newborn; Nitric Oxide; Nitrites; Pregnancy; Reference Values; Regression Analysis; Retrospective Studies; Rh Isoimmunization | 1999 |
Nitric oxide in cyclosporine A-induced hypertension: role of protein kinase C.
Topics: Acetylcholine; Animals; Antihypertensive Agents; Aorta, Thoracic; Arginine; Cyclic GMP; Cyclosporine; Endothelin Receptor Antagonists; Endothelins; Endothelium, Vascular; Hypertension; Immunosuppressive Agents; Male; Nitric Oxide; Protein Kinase C; Rats; Rats, Sprague-Dawley; Vasodilation; Vasodilator Agents | 1999 |
[Role of nitric oxide synthase III and guanosine 3':5'- cyclic monophosphate in the protection exerted by nitric oxide on hepatic ischemia-reperfusion injury].
Topics: Animals; Arginine; Creatine Kinase; Cyclic GMP; Endothelium, Vascular; Immunohistochemistry; L-Lactate Dehydrogenase; Liver; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 1999 |
Effects of endothelin-1 and nitric oxide on glucokinase activity in isolated rat hepatocytes.
Topics: Animals; Arginine; Cells, Cultured; Cyclic GMP; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Glucokinase; Glucose; Glycogen; Kinetics; Liver; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Oligopeptides; Piperidines; Rats; Rats, Sprague-Dawley | 2000 |
Decreased synthesis and vasodilation to nitric oxide in piglets with hypoxia-induced pulmonary hypertension.
Topics: Animals; Animals, Newborn; Arginine; Blood Vessels; Cyclic GMP; Hypertension, Pulmonary; Hypoxia; In Vitro Techniques; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Pulmonary Circulation; Swine; Vasodilation; Vasodilator Agents | 2000 |
Antisteroidogenic action of nitric oxide on human corpus luteum in vitro: mechanism of action.
Topics: Adult; Arginine; Cells, Cultured; Corpus Luteum; Cyclic GMP; Cytochrome P-450 Enzyme System; Depression, Chemical; Enzyme Inhibitors; Estradiol; Female; Humans; Imidazoles; NADPH Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Steroids | 1999 |
Nitric oxide synthase and cGMP activity in the salivary glands of the American dog tick Dermacentor variabilis.
Topics: Animals; Arginine; Chromatography, Gel; Cyclic GMP; Dermacentor; Dopamine; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Female; Histocytochemistry; Immunohistochemistry; Male; Molecular Weight; NADPH Dehydrogenase; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Radioimmunoassay; Salivary Glands; Signal Transduction | 2000 |
Chemical hypoxia-induced increases in dopamine D1A receptor mRNA in renal epithelial cells are mediated by nitric oxide.
Topics: Animals; Arginine; Cyclic GMP; Deoxyglucose; Enzyme Inhibitors; Epithelial Cells; Hypoxia; Kidney; LLC-PK1 Cells; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; omega-N-Methylarginine; Receptors, Dopamine D1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium Cyanide; Swine | 2000 |
delta-opioid receptors and nitric oxide mediate the analgesic effect of Crotalus durissus terrificus snake venom.
Topics: Analgesics, Non-Narcotic; Animals; Arginine; Carrageenan; Crotalid Venoms; Cyclic GMP; Edema; Enzyme Inhibitors; Hyperalgesia; Male; Methylene Blue; Motor Activity; Narcotic Antagonists; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2000 |
Interaction of L-arginine and phosphodiesterase inhibitors in vasodilation of the porcine internal mammary artery.
Topics: Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Drug Synergism; Mammary Arteries; omega-N-Methylarginine; Phosphodiesterase Inhibitors; Swine; Vasodilation | 2000 |
The effects of L-arginine on the release of prolactin from decidual explants in vitro.
Topics: Arginine; Cyclic GMP; Decidua; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pregnancy; Prolactin | 2000 |
Ascorbic acid enhances endothelial nitric-oxide synthase activity by increasing intracellular tetrahydrobiopterin.
Topics: Animals; Aorta; Arginine; Ascorbic Acid; Atrial Natriuretic Factor; Biopterins; Calcimycin; Cattle; Cell Line; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Kinetics; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroprusside; Pteridines; Pterins; Recombinant Proteins; Spodoptera; Swine; Transfection | 2000 |
Is asymmetric dimethylarginine a novel marker of atherosclerosis?
Topics: Arginine; Arteriosclerosis; Biomarkers; Carotid Arteries; Chromatography, High Pressure Liquid; Cyclic GMP; Enzyme Inhibitors; Humans; Nitrates; Nitric Oxide Synthase; Regression Analysis; Stereoisomerism; Tunica Intima | 2000 |
Thyrocyte release of asymmetric dimethylarginine does not account for human thyrocyte inhibition of endothelial cell cyclic GMP.
Topics: Arginine; Cells, Cultured; Chromatography, High Pressure Liquid; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Humans; Nitric Oxide Synthase; Radioimmunoassay; Thyroid Gland; Umbilical Veins | 2000 |
Role of chronic exercise in decreasing oxidized LDL-potentiated platelet activation by enhancing platelet-derived no release and bioactivity in rats.
Topics: Animals; Arginine; Blood Platelets; Cyclic GMP; Dinoprost; F2-Isoprostanes; Hemodynamics; Humans; Lipid Peroxides; Lipids; Lipoproteins, LDL; Male; Nitric Oxide; Physical Conditioning, Animal; Platelet Activation; Platelet Adhesiveness; Platelet Aggregation; Rats; Rats, Wistar | 2000 |
The role of nitric oxide, K(+)(ATP) channels, and cGMP in the preconditioning response of the rabbit.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Arginine; Coronary Circulation; Cyclic GMP; Enzyme Inhibitors; In Vitro Techniques; Ischemic Preconditioning; Male; Methylene Blue; Muscle Fibers, Skeletal; Myocardial Infarction; Myocardial Ischemia; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Potassium Channels; Rabbits | 2000 |
L-NAME causes antinociception by stimulation of the arginine-NO-cGMP pathway.
Topics: Analgesics; Animals; Arginine; Carrageenan; Cyclic GMP; Dinoprostone; Hyperalgesia; Male; Methylene Blue; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Oxadiazoles; Phosphodiesterase Inhibitors; Phthalazines; Quinoxalines; Rats; Rats, Wistar; Signal Transduction | 2000 |
L-Arginine administration prevents reperfusion-induced cardiomyocyte hypercontracture and reduces infarct size in the pig.
Topics: Analysis of Variance; Animals; Arginine; Blood Pressure; Cell Size; Cyclic GMP; Female; Heart Rate; Male; Myocardial Contraction; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Peroxidase; Random Allocation; Swine | 2000 |
Nitric oxide regulates the aggregation of stimulated human neutrophils.
Topics: Actins; Antibodies; Arginine; CD18 Antigens; Cell Aggregation; Cyclic GMP; Cytochalasin B; Drug Synergism; Flow Cytometry; Humans; L-Selectin; Macrophage-1 Antigen; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide; Tetradecanoylphorbol Acetate | 2000 |
Regulation of ciliary beat frequency by the nitric oxide-cyclic guanosine monophosphate signaling pathway in rat airway epithelial cells.
Topics: Alkaloids; Animals; Arginine; Carbazoles; Cells, Cultured; Cilia; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Glutathione; Indoles; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; omega-N-Methylarginine; Oxadiazoles; Purinones; Quinoxalines; Rats; S-Nitrosoglutathione; Signal Transduction; Trachea | 2000 |
Nitric oxide-induced cGMP accumulation in the mouse bladder is not related to smooth muscle relaxation.
Topics: Animals; Arginine; Carbachol; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Female; In Vitro Techniques; Mice; Mice, Inbred BALB C; Molsidomine; Muscle Relaxation; Muscle, Smooth; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Phosphodiesterase Inhibitors; Piperazines; Piperidines; Purines; Quinazolines; Sildenafil Citrate; Sulfones; Urethra; Urinary Bladder | 2000 |
Participation of the components of L-arginine/nitric oxide/cGMP cascade by chemically-induced abdominal constriction in the mouse.
Topics: Abdominal Pain; Analgesics; Animals; Arginine; Benzoquinones; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Male; Methylene Blue; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pain Measurement | 2000 |
Effect of chronic treatment with the inducible nitric oxide synthase inhibitor N-iminoethyl-L-lysine or with L-arginine on progression of coronary and aortic atherosclerosis in hypercholesterolemic rabbits.
Topics: Animals; Aorta, Thoracic; Arginine; Blood Cell Count; Cholesterol, Dietary; Collagen; Coronary Artery Disease; Coronary Vessels; Cyclic GMP; Enzyme Inhibitors; Hemodynamics; Hypercholesterolemia; Immunohistochemistry; Lysine; Macrophages; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rabbits; T-Lymphocytes | 2000 |
Failure of L-arginine to induce hypotension in patients with a history of accelerated-malignant hypertension.
Topics: Aged; Arginine; Blood Pressure; Cyclic GMP; Endothelium, Vascular; Female; Humans; Hypertension, Malignant; Male; Middle Aged | 2000 |
Increased nitric oxide synthase activity and expression in the human uterine artery during pregnancy.
Topics: Adult; Arginine; Arteries; Blotting, Western; Calcium Chloride; Calmodulin; Cyclic GMP; Edetic Acid; Endothelium, Vascular; Enzyme Inhibitors; Female; Gene Expression Regulation, Enzymologic; Humans; Immunohistochemistry; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Pregnancy; Up-Regulation; Uterus; Vasodilation | 2000 |
Modulation of the nitric oxide pathway by copper in glial cells.
Topics: Animals; Arginine; Citrulline; Copper; Cyclic GMP; Gene Expression Regulation, Enzymologic; Interferon-gamma; Isoenzymes; Lipopolysaccharides; Neuroglia; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitrites; Rats; RNA, Messenger; Tumor Cells, Cultured | 2000 |
Nitric oxide improves membrane fluidity of erythrocytes in essential hypertension: An electron paramagnetic resonance investigation.
Topics: Arginine; Blood Pressure; Calcimycin; Cell Membrane; Cyclic GMP; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Erythrocytes; Hemorheology; Humans; Hypertension; Membrane Fluidity; Middle Aged; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Penicillamine; Spin Labels | 2000 |
Gastrointestinal motility during pregnancy: role of nitrergic component of NANC nerves.
Topics: Acetylcholine; Animals; Arginine; Atropine; Colon; Cyclic GMP; Electric Stimulation; Enzyme Inhibitors; Female; Gastric Fundus; Gastrointestinal Motility; Ileum; In Vitro Techniques; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phentolamine; Pregnancy; Pregnancy, Animal; Propranolol; Rats; Rats, Sprague-Dawley; Stomach | 2000 |
Pre-synaptic NO-cGMP pathway modulates vagal control of heart rate in isolated adult guinea pig atria.
Topics: Age Factors; Animals; Aortic Bodies; Arginine; Blotting, Western; Carbachol; Cardiotonic Agents; Cyclic GMP; Digestive System; Enzyme Inhibitors; Female; Guanylate Cyclase; Guinea Pigs; Heart Atria; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Ornithine; Oxadiazoles; Prosencephalon; Quinoxalines; Receptors, Atrial Natriuretic Factor; Time Factors | 2000 |
Autocrine effects of nitric oxide on HCO(3)(-) transport by rat thick ascending limb.
Topics: Alkaloids; Animals; Arginine; Autocrine Communication; Bicarbonates; Biological Transport; Carbazoles; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; In Vitro Techniques; Indoles; Loop of Henle; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley | 2000 |
Nitric oxide modulates intracellular translocation of pigment organelles in Xenopus laevis melanophores.
Topics: Alkaloids; Animals; Arginine; Biological Transport; Blotting, Western; Carbazoles; Cells, Cultured; Cyclic GMP; Cytoskeleton; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Guanylate Cyclase; Indoles; Melanophores; Microscopy, Fluorescence; Models, Biological; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Quinoxalines; Signal Transduction; Time Factors; Xenopus laevis | 2000 |
Hypercholesterolemia inhibits angiogenesis in response to hindlimb ischemia: nitric oxide-dependent mechanism.
Topics: Administration, Oral; Animals; Arginine; Body Weight; Cholesterol, Dietary; Collateral Circulation; Cyclic GMP; Endothelium, Vascular; Hindlimb; Hypercholesterolemia; Immunohistochemistry; Ischemia; Laser-Doppler Flowmetry; Lipids; Male; Neovascularization, Physiologic; Nitrates; Nitric Oxide; Nitrites; Rats; Rats, Sprague-Dawley; Regional Blood Flow | 2000 |
Hyperhomocysteinemia impairs angiogenesis in response to hindlimb ischemia.
Topics: Angiography; Animals; Arginine; Blood Pressure; Body Weight; Collateral Circulation; Cyclic GMP; Disease Models, Animal; Heart Rate; Hindlimb; Homocysteine; Hyperhomocysteinemia; Immunohistochemistry; Ischemia; Laser-Doppler Flowmetry; Muscle, Skeletal; Neovascularization, Physiologic; Nitrates; Nitrites; Rats; Regional Blood Flow; Time Factors | 2000 |
Platelet responsiveness to L-arginine in hypertensive disorders of pregnancy.
Topics: Adult; Analysis of Variance; Antihypertensive Agents; Arginine; Birth Weight; Blood Pressure; Case-Control Studies; Cesarean Section; Chronic Disease; Cross-Sectional Studies; Cyclic GMP; Female; Gestational Age; Humans; Hypertension; Nitric Oxide Donors; Nitroprusside; Platelet Aggregation; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Statistics, Nonparametric | 2000 |
Nitric oxide modulation of interleukin-1[beta]-evoked intracellular Ca2+ release in human astrocytoma U-373 MG cells and brain striatal slices.
Topics: Aminoquinolines; Animals; Arginine; Astrocytoma; Calcium; Corpus Striatum; Cyclic GMP; Dibutyryl Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Heparin; Humans; Hydrazines; In Vitro Techniques; Interleukin-1; Intracellular Fluid; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Ruthenium Red; Spermine; Tumor Cells, Cultured | 2000 |
Impaired renal vascular endothelial function in vitro in experimental hypercholesterolemia.
Topics: Animals; Arginine; Cholesterol; Cyclic GMP; Diethylamines; Endothelium, Vascular; Hemodynamics; Hypercholesterolemia; In Vitro Techniques; Nitric Oxide; Nitric Oxide Donors; Reference Values; Renal Circulation; Swine; Vasomotor System | 2001 |
Upregulation of the nitric oxide-cGMP pathway in aged myocardium: physiological response to l-arginine.
Topics: Aging; Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Female; Heart; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroprusside; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Signal Transduction; Up-Regulation | 2001 |
Paradoxical increase in nitric oxide synthase activity in hypercholesterolaemic rats with impaired renal function and decreased activity of nitric oxide.
Topics: Animals; Arginine; Cholesterol, Dietary; Cyclic GMP; Hypercholesterolemia; Kidney; Male; NADPH Dehydrogenase; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Sprague-Dawley; Reference Values | 2001 |
Modulation of neuronal nitric oxide release by soluble guanylyl cyclase in guinea pig colon.
Topics: Animals; Arginine; Colon; Cyclic GMP; Dimethyl Sulfoxide; Electrophysiology; Enzyme Inhibitors; Guanylate Cyclase; Guinea Pigs; Immunohistochemistry; Male; Muscle, Smooth; Neurons; Nitric Oxide; Oxadiazoles; Phosphodiesterase Inhibitors; Purinones; Quinoxalines | 2001 |
Effects of the nitric oxide/cGMP system compared with the cAMP system on airway mucus secretion in the rat.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Arginine; Atrial Natriuretic Factor; Cyclic AMP; Cyclic GMP; Enzyme Activators; Enzyme Inhibitors; Isoenzymes; Male; Mucins; Mucus; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Sulfur Radioisotopes; Trachea | 2001 |
NO/cGMP signaling modulates regulation of Na+-K+-ATPase activity by angiotensin II in rat proximal tubules.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arginine; Calcium; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Intracellular Membranes; Kidney Tubules, Proximal; Male; Nitric Oxide; omega-N-Methylarginine; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Signal Transduction; Sodium-Potassium-Exchanging ATPase; Solubility | 2001 |
Paracrine neuroprotective effect of nitric oxide in the developing retina.
Topics: Animals; Animals, Newborn; Anisomycin; Arginine; Biopterins; Cell Death; Cells, Cultured; Cyclic GMP; Guanylate Cyclase; In Vitro Techniques; NADPH Dehydrogenase; Neuroprotective Agents; Nitric Oxide; Paracrine Communication; Penicillamine; Pteridines; Pterins; Rats; Rats, Inbred Strains; Retina; Retinal Ganglion Cells; S-Nitroso-N-Acetylpenicillamine | 2001 |
L-arginine partially reverses established adrenocorticotrophin-induced hypertension and nitric oxide deficiency in the rat.
Topics: Adrenocorticotropic Hormone; Amino Acids; Animals; Arginine; Citrulline; Cyclic GMP; Drug Evaluation; Hypertension; Male; Nitrates; Nitric Oxide; Nitrites; Random Allocation; Rats; Rats, Sprague-Dawley; Stereoisomerism | 2000 |
Neural network partitioning by NO and cGMP.
Topics: Animals; Arginine; Brachyura; Citrulline; Cyclic GMP; Digestive System; Enzyme Inhibitors; Fluorescent Dyes; Ganglia, Invertebrate; Guanylate Cyclase; Immunohistochemistry; In Vitro Techniques; Isoquinolines; Male; Nerve Net; Neurons; Neurotransmitter Agents; Nitric Oxide; Nitric Oxide Donors; Periodicity; Signal Transduction | 2001 |
Vasoactive mediator release by fetal endothelial cells in intrauterine growth restriction and preeclampsia.
Topics: 6-Ketoprostaglandin F1 alpha; Adolescent; Adult; Arginine; Case-Control Studies; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Female; Fetal Growth Retardation; Humans; Kinetics; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pre-Eclampsia; Pregnancy; Scintillation Counting; Statistics, Nonparametric; Tritium; Umbilical Veins | 2001 |
NO Inhibits NaCl absorption by rat thick ascending limb through activation of cGMP-stimulated phosphodiesterase.
Topics: Adenine; Alkaloids; Aminoquinolines; Animals; Arginine; Carbazoles; Cyclic AMP; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Exonucleases; Guanylate Cyclase; Indoles; Kidney Tubules, Distal; Male; Nitric Oxide; Perfusion; Rats; Rats, Sprague-Dawley; Sodium Chloride | 2001 |
Opposing actions of nitric oxide on synaptic inputs of identified interneurones in the central nervous system of the crayfish.
Topics: Animals; Arginine; Astacoidea; Cyclic GMP; Cyclic N-Oxides; Electric Stimulation; Electrophysiology; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Female; Free Radical Scavengers; Ganglia, Invertebrate; Imidazoles; In Vitro Techniques; Interneurons; Male; Mechanoreceptors; Nerve Net; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Penicillamine; Quinoxalines; S-Nitroso-N-Acetylpenicillamine; Synapses; Synaptic Transmission | 2001 |
Role of the arginine-nitric oxide pathway in the regulation of vascular smooth muscle cell proliferation.
Topics: Animals; Arginine; Cell Division; Cells, Cultured; Cyclic GMP; Muscle, Smooth, Vascular; Nitric Oxide; Ornithine Decarboxylase; Polyamines; Rats | 2001 |
Hypochlorite-modified low density lipoprotein inhibits nitric oxide synthesis in endothelial cells via an intracellular dislocalization of endothelial nitric-oxide synthase.
Topics: Antioxidants; Arginine; Biopterins; Blotting, Western; Cell Membrane; Cells, Cultured; Centrifugation, Density Gradient; Citrulline; Cyclic GMP; Cyclodextrins; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Endothelium, Vascular; Golgi Apparatus; Humans; Hypochlorous Acid; Immunoblotting; Immunohistochemistry; Ionomycin; Ionophores; Lipoproteins, LDL; Microscopy, Fluorescence; Myristic Acids; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Palmitic Acids; Precipitin Tests; RNA, Messenger; Subcellular Fractions; Sucrose; Time Factors; Umbilical Veins | 2001 |
L-Arginine improves endothelial function in renal artery of hypertensive Dahl rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Arginine; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Cyclic GMP; Endothelins; Endothelium, Vascular; Fatty Acids, Unsaturated; Hydralazine; Hydrazines; Hypertension; In Vitro Techniques; Indomethacin; Male; Methacrylates; Natriuresis; Nitrates; Nitrites; Nitroprusside; Rats; Rats, Inbred Dahl; Renal Artery; Thromboxane A2; Vasoconstriction | 2001 |
Regulation of cardiac calcium current by NO and cGMP-modulating agents.
Topics: Adenine; Animals; Arginine; Biological Transport; Calcium Channels, L-Type; Carbachol; Cholinergic Agonists; Cyclic GMP; Cyclic N-Oxides; Enzyme Inhibitors; Exonucleases; Free Radical Scavengers; Guinea Pigs; Imidazoles; In Vitro Techniques; Myocardium; Nitric Oxide; omega-N-Methylarginine; Orchiectomy; Oxadiazoles; Quinoxalines; Receptors, Muscarinic | 2001 |
Peroxynitrite leads to arteriolar smooth muscle cell membrane hyperpolarization and low vasoreactivity in severe shock.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Animals; Arginine; Arterioles; Charybdotoxin; Cyclic GMP; Drug Interactions; Female; Free Radical Scavengers; Glyburide; Guanidines; Ion Transport; Male; Membrane Potentials; Mesenteric Arteries; Microscopy, Confocal; Microscopy, Fluorescence; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide Donors; Norepinephrine; Oxadiazoles; Penicillamine; Potassium; Potassium Channels; Quinoxalines; Rats; Rats, Sprague-Dawley; Shock, Hemorrhagic; Vasodilator Agents | 2000 |
Involvement of accumulated endogenous NOS inhibitors and decreased NOS activity in the impaired neurogenic relaxation of the rabbit proximal urethra with ischaemia.
Topics: Animals; Arginine; Blood Pressure; Body Weight; Cyclic GMP; Electric Stimulation; Enzyme Inhibitors; Iliac Artery; In Vitro Techniques; Ischemia; Male; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Phenylephrine; Rabbits; Urethra | 2001 |
Role of nitric oxide and mucus in ischemia/reperfusion-induced gastric mucosal injury in rats.
Topics: Animals; Arginine; Cyclic GMP; Gastric Mucosa; Glutathione; Glutathione Peroxidase; Lipid Peroxides; Male; Mucus; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2001 |
Stimulation of endogenous nitric oxide production is involved in the inhibitory effect of adrenomedullin on aldosterone secretion in the rat.
Topics: Adrenomedullin; Aldosterone; Amidines; Aminoquinolines; Animals; Arginine; Benzylamines; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peptides; Potassium; Rats; Rats, Wistar; Zona Glomerulosa | 2001 |
Involvement of cyclic guanosine 3',5'-monophosphate in nitric oxide-induced glucagon secretion from pancreatic alpha cells.
Topics: Animals; Arginine; Cell Line; Cyclic GMP; Glucagon; Islets of Langerhans; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Triazenes | 2001 |
Hypoxia impairs endothelium-dependent relaxation in organ cultured pulmonary artery.
Topics: Animals; Arginine; Biopterins; Caveolin 1; Caveolins; Cyclic GMP; Dinoprost; Dose-Response Relationship, Drug; Endothelium, Vascular; Hypoxia; Ionomycin; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroprusside; Organ Culture Techniques; Pulmonary Artery; Rabbits; RNA, Messenger; Substance P; Superoxide Dismutase; Vasoconstriction; Vasodilation; Vasodilator Agents | 2001 |
Estriol improves membrane fluidity of erythrocytes by the nitric oxide-dependent mechanism: an electron paramagnetic resonance study.
Topics: Arginine; Cyclic GMP; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Erythrocyte Membrane; Estriol; Female; Humans; In Vitro Techniques; Male; Membrane Fluidity; Middle Aged; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Penicillamine | 2001 |
Sildenafil-induced peripheral analgesia and activation of the nitric oxide-cyclic GMP pathway.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Acetic Acid; Analgesia; Animals; Arginine; Carrageenan; Central Nervous System; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Dose-Response Relationship, Drug; Female; Hyperalgesia; Male; Methylene Blue; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Nociceptors; Pain; Pain Measurement; Pain Threshold; Peripheral Nervous System; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Piperazines; Purines; Signal Transduction; Sildenafil Citrate; Sulfones | 2001 |
Electron paramagnetic resonance investigation on modulatory effect of 17beta-estradiol on membrane fluidity of erythrocytes in postmenopausal women.
Topics: Aged; Arginine; Cyclic GMP; Electron Spin Resonance Spectroscopy; Erythrocytes; Estradiol; Female; Humans; Hypertension; In Vitro Techniques; Membrane Fluidity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Penicillamine; Postmenopause; S-Nitroso-N-Acetylpenicillamine | 2001 |
Effect of ACE inhibitor captopril and L-arginine on the metabolism and on ischemia-reperfusion injury of the isolated rat heart.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Captopril; Cyclic GMP; Drug Synergism; In Vitro Techniques; Male; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; Rats; Rats, Wistar | 2001 |
Response of nitric oxide pathway to L-arginine infusion at the altitude of 4,350 m.
Topics: Adult; Altitude; Altitude Sickness; Arginine; Citrulline; Cyclic GMP; Female; Humans; Hypoxia; Infusions, Intravenous; Linear Models; Male; Nitric Oxide; Oxygen; Radioimmunoassay; Reference Values; Time Factors | 2001 |
Renal interstitial cGMP mediates natriuresis by direct tubule mechanism.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Anesthesia; Animals; Arginine; Bacterial Toxins; Benzimidazoles; Consciousness; Cyclic AMP; Cyclic GMP; Enterotoxins; Escherichia coli Proteins; Female; Glomerular Filtration Rate; Kidney; Kidney Tubules; Microscopy, Fluorescence; Natriuresis; Nephrectomy; NG-Nitroarginine Methyl Ester; Oxadiazoles; Penicillamine; Quinoxalines; Rats; Rats, Sprague-Dawley; Renal Circulation; Sodium; Thionucleotides; Xanthenes | 2001 |
Increased contribution of L-arginine-nitric oxide pathway in aorta of mice lacking the gene for vimentin.
Topics: Acetylcholine; Animals; Aorta; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Signal Transduction; Vasoconstriction; Vasodilation; Vasodilator Agents; Vimentin | 2001 |
Metabolites of the L-arginine-NO pathway in patients with left-to-right shunt.
Topics: Adolescent; Adult; Age Factors; Arginine; Arteriovenous Shunt, Surgical; Cardiac Catheterization; Case-Control Studies; Child; Child, Preschool; Cyclic GMP; Endocardial Cushion Defects; Female; Heart Septal Defects; Hemodynamics; Humans; Hypertension, Pulmonary; Infant; Male; Nitrates; Nitric Oxide; Pulmonary Circulation | 2001 |
Effects of the reactive oxygen species hydrogen peroxide and hypochlorite on endothelial nitric oxide production.
Topics: Adenosine Diphosphate; Animals; Arginine; Bradykinin; Calcimycin; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Hydrogen Peroxide; Hypochlorous Acid; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroprusside; omega-N-Methylarginine; Oxidants; Swine | 2001 |
Basal tonic release of nitric oxide coupled to cGMP production regulates the vascular reactivity of the mesenteric bed.
Topics: Acetylcholine; Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Male; Mesenteric Arteries; Nitric Oxide; Nitroarginine; Norepinephrine; Oxadiazoles; Piperazines; Purines; Quinoxalines; Rats; Rats, Sprague-Dawley; Sildenafil Citrate; Sulfones; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2001 |
Bax and caspases are inhibited by endogenous nitric oxide in dorsal root ganglion neurons in vitro.
Topics: Animals; Animals, Newborn; Apoptosis; Arginine; Autocrine Communication; bcl-2-Associated X Protein; Caspase Inhibitors; Caspases; Cells, Cultured; Cyclic GMP; Enzyme Inhibitors; Female; Ganglia, Spinal; Immunohistochemistry; Male; Nerve Degeneration; Neurons, Afferent; Nitric Oxide; Nitric Oxide Synthase; Peripheral Nervous System Diseases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Signal Transduction; Stress, Physiological | 2001 |
The role of L-arginine/nitric oxide pathway in the antinociceptive activity of pyridoxine in mouse.
Topics: Analgesics; Analgesics, Opioid; Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Male; Methylene Blue; Mice; Morphine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pyridoxine; Vitamin B 6 | 2001 |
L-citrulline mediated relaxation in the control and lipopolysaccharide-treated rat aortic rings.
Topics: Animals; Aorta; Arginine; Citrulline; Corticosterone; Cyclic GMP; Cycloheximide; Glutamine; Guanidines; In Vitro Techniques; Lipopolysaccharides; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitrites; Potassium Channels; Rats; Rats, Sprague-Dawley; Vasodilation | 2001 |
Myocyte function and [Ca 2+ ]i homeostasis during early allogenic heart transplant rejection.
Topics: Animals; Arginine; Calcium; Cyclic GMP; Graft Rejection; Heart Transplantation; Homeostasis; Isoproterenol; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Myocardial Contraction; Nitric Oxide Synthase; Transplantation, Homologous | 2001 |
Effects of intracavernous administration of adrenomedullin on erectile function in rats.
Topics: Adrenomedullin; Animals; Arginine; Cyclic GMP; Disease Models, Animal; Enzyme Inhibitors; Erectile Dysfunction; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Penile Erection; Peptides; Phosphodiesterase Inhibitors; Piperidines; Quinazolines; Rats; Rats, Wistar | 2001 |
Endogenous nitric oxide synthase inhibitors in endothelial cells, endothelin-1 within the vessel wall, and intimal hyperplasia in perimenopausal human uterine arteries.
Topics: Adult; Arginine; Arteries; Chromatography, High Pressure Liquid; Climacteric; Cyclic GMP; Endothelin-1; Endothelium, Vascular; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Female; Humans; Hyperplasia; In Vitro Techniques; Middle Aged; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Tunica Intima; Tunica Media; Uterus | 2002 |
Experimental evidence for a non-renin mediated pathway during TAME-esterase induced contractions in rat aorta in vitro.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Arginine; Captopril; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Male; Methylene Blue; Muscle Contraction; Muscle, Smooth, Vascular; Peptide Hydrolases; Rats; Rats, Sprague-Dawley; Renin; Signal Transduction; Tosylarginine Methyl Ester; Vasoconstriction | 2001 |
Mechanisms involved in protection afforded by L-arginine in ibuprofen-induced gastric damage: role of nitric oxide and prostaglandins.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Cyclic GMP; Gastric Mucosa; Ibuprofen; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroarginine; Prostaglandins; Rats; Rats, Wistar | 2002 |
L-arginine rescues decreased erythropoietin gene expression by stimulating GATA-2 with L-NMMA.
Topics: Anemia; Animals; Arginine; Cell Hypoxia; Cells, Cultured; Cyclic GMP; DNA-Binding Proteins; Enzyme Inhibitors; Erythropoietin; GATA2 Transcription Factor; Gene Expression; Humans; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Oxygen; Promoter Regions, Genetic; RNA, Messenger; Transcription Factors; Uremia | 2002 |
Comparison of nitric oxide donors in lowering intraocular pressure in rabbits: role of cyclic GMP.
Topics: Animals; Arginine; Cyclic GMP; Female; Indazoles; Intraocular Pressure; Male; Nitric Oxide Donors; Nitric Oxide Synthase; Purinones; Rabbits | 2002 |
Photic regulation of L-arginine uptake in the golden hamster retina.
Topics: Animals; Arginine; Cationic Amino Acid Transporter 1; Cationic Amino Acid Transporter 2; Cricetinae; Cyclic GMP; Gene Expression; Male; Mesocricetus; Photic Stimulation; Photoperiod; Retina; RNA, Messenger; Signal Transduction; Tritium | 2002 |
Dynamics of nitric oxide during simulated ischaemia-reperfusion in rat striatal slices measured using an intrinsic biosensor, soluble guanylyl cyclase.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Biosensing Techniques; Brain Ischemia; Cyclic GMP; Guanylate Cyclase; NADPH Dehydrogenase; Neostriatum; Neurons; Nitric Oxide; Nitric Oxide Synthase; Phosphodiesterase Inhibitors; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reperfusion Injury | 2002 |
Biochemical markers of the L-arginine-nitric oxide pathway in the aqueous humour in glaucoma patients.
Topics: Aged; Aqueous Humor; Arginine; Biomarkers; Blood Pressure; Cataract; Cyclic GMP; Female; Glaucoma; Humans; Intraocular Pressure; Male; Nitrates; Nitric Oxide; Nitrites; Prospective Studies; Signal Transduction | 2002 |
[Effects of myocardial ischemia reperfusion injury on L-arginine/nitric oxide system in rat heart].
Topics: Animals; Arginine; Cyclic GMP; Female; Male; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Wistar | 1999 |
Inhibitory effect of N(G)-nitro-L-arginine methyl ester on the anti-adrenergic response elicited by ayanin in the pithed rat.
Topics: Animals; Arginine; Blood Pressure; Croton; Cyclic GMP; Decerebrate State; Dose-Response Relationship, Drug; Flavonoids; Heart Rate; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Rats; Toxicity Tests, Acute | 2002 |
Accumulated endogenous NOS inhibitors, decreased NOS activity, and impaired cavernosal relaxation with ischemia.
Topics: Animals; Arginine; Calcium; Carbachol; Cholinergic Agonists; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Endothelium, Vascular; Enzyme Inhibitors; Iliac Artery; Impotence, Vasculogenic; In Vitro Techniques; Ischemia; Male; Nitric Oxide Synthase; omega-N-Methylarginine; Penis; Rabbits; Vasoconstrictor Agents; Vasodilator Agents | 2002 |
Nitric oxide-cGMP-mediated vasoconstriction and effects of acetylcholine in the branchial circulation of the eel.
Topics: Acetylcholine; Animals; Arginine; Branchial Region; Cyclic GMP; Dose-Response Relationship, Drug; Eels; Endothelium, Vascular; Female; Gills; Hemoglobins; In Vitro Techniques; Male; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Vasoconstriction | 2002 |
L-Arginine/nitric oxide pathway in chronic tension-type headache: relation with serotonin content and secretion and glutamate content.
Topics: Adult; Arginine; Blood Platelets; Calcium; Chronic Disease; Collagen; Cyclic GMP; Cytosol; Female; Glutamic Acid; Humans; Male; Middle Aged; Nitric Oxide; Platelet Aggregation; Reference Values; Serotonin; Tension-Type Headache | 2002 |
Modulation by peroxynitrite of Akt- and AMP-activated kinase-dependent Ser1179 phosphorylation of endothelial nitric oxide synthase.
Topics: Adenoviridae; AMP-Activated Protein Kinases; Animals; Arginine; Blotting, Western; Cattle; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Enzyme Activation; Genes, Dominant; Multienzyme Complexes; Mutation; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxygen; Peroxynitrous Acid; Phosphorylation; Precipitin Tests; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Serine; Time Factors; Transfection; Up-Regulation; Zinc | 2002 |
Physiological concentrations of melatonin inhibit the nitridergic pathway in the Syrian hamster retina.
Topics: Animals; Arginine; Cricetinae; Cyclic GMP; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Melatonin; Mesocricetus; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Retina; Signal Transduction; Trifluoperazine | 2002 |
Modulation of L-arginine transport and nitric oxide production by gabexate mesylate.
Topics: Anticoagulants; Arginine; Biological Transport; Blood Platelets; Cell Survival; Cell-Free System; Cyclic GMP; Gabexate; Humans; In Vitro Techniques; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I | 2002 |
Synaptic inputs onto spiking local interneurons in crayfish are depressed by nitric oxide.
Topics: Action Potentials; Animals; Arginine; Astacoidea; Cyclic GMP; Cyclic N-Oxides; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Female; Free Radical Scavengers; Imidazoles; Interneurons; Male; Neurons, Afferent; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; Synapses | 2002 |
Endothelial nitric oxide modulates perivascular sensory neurotransmission in the rat isolated mesenteric arterial bed.
Topics: Animals; Arginine; Bucladesine; Calcitonin Gene-Related Peptide; Capsaicin; Cyclic GMP; Electric Stimulation; Endothelium, Vascular; In Vitro Techniques; Indazoles; Male; Mesenteric Arteries; Neurons, Afferent; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitroprusside; Rats; Rats, Wistar; Vasodilation; Vasodilator Agents | 2002 |
Impaired nitric oxide synthase pathway in diabetes mellitus: role of asymmetric dimethylarginine and dimethylarginine dimethylaminohydrolase.
Topics: Amidohydrolases; Animals; Antioxidants; Aorta; Arginine; Cell Line; Cells, Cultured; Cyclic GMP; Diabetes Mellitus, Experimental; Endothelium, Vascular; Enzyme Inhibitors; Glucose; Humans; Male; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Oxidative Stress; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2002 |
Reduction of cGMP and nitric oxide has antidepressant-like effects in the forced swimming test in rats.
Topics: Animals; Antidepressive Agents, Tricyclic; Arginine; Cyclic GMP; Depression; Dimethyl Sulfoxide; Enzyme Inhibitors; Guanylate Cyclase; Imipramine; Indazoles; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Swimming | 2002 |
Effects of nitric oxide on P2Y receptor resensitization in spontaneously hypertensive rat mesangial cells.
Topics: Adenosine Triphosphate; Animals; Arginine; Calcium; Cells, Cultured; Cyclic GMP; Cytosol; Enzyme Inhibitors; Glomerular Mesangium; Guanylate Cyclase; Hypertension; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrogen Oxides; Osmolar Concentration; Oxadiazoles; Quinoxalines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Purinergic P2; Spermine | 2002 |
Long-term treatment with N(omega)-nitro-L-arginine methyl ester causes arteriosclerotic coronary lesions in endothelial nitric oxide synthase-deficient mice.
Topics: Acridines; Administration, Oral; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Arginine; Blood Pressure; Coronary Artery Disease; Coronary Vessels; Cyclic GMP; Disease Progression; Luminescent Measurements; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microcirculation; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidation-Reduction; Peptidyl-Dipeptidase A; Time | 2002 |
Early activation of the p42/p44MAPK pathway mediates adenosine-induced nitric oxide production in human endothelial cells: a novel calcium-insensitive mechanism.
Topics: Adenosine; Androstadienes; Arginine; Biological Transport; Butadienes; Calcium; Cells, Cultured; Chromones; Colforsin; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Fetus; Flavonoids; Gene Expression; Genistein; Humans; Hydrogen-Ion Concentration; MAP Kinase Signaling System; Membrane Potentials; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitriles; Phenethylamines; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Potassium; Protein Isoforms; Purinergic P1 Receptor Agonists; Receptors, Purinergic P1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Wortmannin | 2002 |
Involvement of NO in the endothelium-independent relaxing effects of N(omega)-hydroxy-L-arginine and other compounds bearing a C=NOH function in the rat aorta.
Topics: Animals; Aorta, Thoracic; Arginine; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Indicators and Reagents; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NADPH-Ferrihemoprotein Reductase; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Organic Cation Transport Proteins; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar | 2002 |
The kappa-opioid agonist (+/-)-bremazocine elicits peripheral antinociception by activation of the L-arginine/nitric oxide/cyclic GMP pathway.
Topics: Analgesics; Animals; Arginine; Benzomorphans; Cyclic GMP; Guanylate Cyclase; Hyperalgesia; Male; Methylene Blue; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Pain; Phosphodiesterase Inhibitors; Purinones; Rats; Rats, Wistar; Receptors, Opioid, kappa | 2002 |
Esophageal dysmotility and the change of synthesis of nitric oxide in a feline esophagitis model.
Topics: Animals; Arginine; Cyclic GMP; Disease Models, Animal; Esophageal Motility Disorders; Esophagitis; Male; Nitric Oxide; Nitric Oxide Synthase; Probability; Random Allocation; Reference Values; Sensitivity and Specificity | 2002 |
Functional role of inhibitory and excitatory nerves in the porcine lower urinary tract.
Topics: Adrenergic alpha-Antagonists; Animals; Arginine; Atropine; Cyclic GMP; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Papaverine; Prazosin; Swine; Tetrodotoxin; Urethra; Urinary Bladder; Urinary Tract; Vasodilator Agents; Yohimbine | 2002 |
Effects of nitric oxide on red blood cell deformability.
Topics: Adult; Arginine; Calcium; Cell Size; Cyclic GMP; Drug Interactions; Enzyme Inhibitors; Erythrocyte Deformability; Erythrocytes; Guanylate Cyclase; Hemorheology; Humans; Hydrazines; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Nitroso Compounds; Potassium Channel Blockers; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Stress, Mechanical; Tetraethylammonium | 2003 |
Activation and potentiation of the NO/cGMP pathway by NG-hydroxyl-L-arginine in rabbit corpus cavernosum under normoxic and hypoxic conditions and ageing.
Topics: Aging; Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Hydroxyl Radical; Hypoxia; In Vitro Techniques; Male; Nitric Oxide; Penis; Rabbits; Vasodilation | 2003 |
Effects of L-arginine and sodium nitroprusside on the spontaneous contractility of human non-pregnant uterus.
Topics: Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Drug Synergism; Female; Humans; In Vitro Techniques; Methylene Blue; Middle Aged; Nitric Oxide Donors; Nitroprusside; Osmolar Concentration; Uterine Contraction; Uterus | 2003 |
A mouse model of argininosuccinic aciduria: biochemical characterization.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Arginase; Arginine; Argininosuccinate Lyase; Argininosuccinic Acid; Argininosuccinic Aciduria; Carbamoyl-Phosphate Synthase (Ammonia); Cyclic GMP; Disease Models, Animal; Female; Genotype; Humans; Hyperammonemia; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Nitric Oxide; Ornithine Carbamoyltransferase; Urea | 2003 |
On the role of nitric oxide in hippocampal long-term potentiation.
Topics: Animals; Arginine; Cyclic GMP; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Guanylate Cyclase; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Neurons, Afferent; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Receptors, N-Methyl-D-Aspartate; Soluble Guanylyl Cyclase; Synaptic Transmission | 2003 |
The effect of L-arginine on slow motility of mammalian outer hair cell.
Topics: Animals; Arginine; Calcium; Cell Membrane Permeability; Cell Movement; Cell Size; Cyclic GMP; Enzyme Inhibitors; Extracellular Fluid; Guinea Pigs; Hair Cells, Auditory, Outer; Indazoles; Intracellular Membranes; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Osmolar Concentration | 2003 |
Platelet-activating factor synthesis by neutrophils, monocytes, and endothelial cells is modulated by nitric oxide production.
Topics: Adult; Arginine; Cells, Cultured; Cyclic GMP; Drug Synergism; Endothelium, Vascular; Enzyme Inhibitors; Humans; Lipopolysaccharides; Monocytes; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Platelet Activating Factor; Stereoisomerism; Tumor Necrosis Factor-alpha | 2003 |
Transport of L-arginine and nitric oxide formation in human platelets.
Topics: Anti-Bacterial Agents; Arginine; Biological Transport; Blood Platelets; Cyclic GMP; Enzyme Inhibitors; Ethylmaleimide; Gramicidin; Humans; Ionophores; Leucine; Membrane Transport Proteins; Nitric Oxide; Quaternary Ammonium Compounds; Sodium; Valinomycin | 2003 |
Opposite nociceptive effects of the arginine/NO/cGMP pathway stimulation in dermal and subcutaneous tissues.
Topics: Animals; Arginine; Bucladesine; Cyclic GMP; Dermis; Dinoprostone; Dose-Response Relationship, Drug; Hyperalgesia; Injections, Subcutaneous; Male; Molsidomine; Nitric Oxide; Nociceptors; omega-N-Methylarginine; Oxadiazoles; Pain Measurement; Quinoxalines; Rats; Rats, Wistar; Subcutaneous Tissue; Time Factors | 2003 |
Fluoxetine suppresses morphine tolerance and dependence: modulation of NO-cGMP/DA/serotoninergic pathways.
Topics: Animals; Arginine; Body Weight; Cyclic GMP; Depression, Chemical; Diarrhea; Dopamine; Drug Interactions; Drug Tolerance; Female; Fluoxetine; Male; Mice; Morphine Dependence; Naloxone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Selective Serotonin Reuptake Inhibitors; Serotonin; Substance Withdrawal Syndrome | 2003 |
Chronic ischemia increases prostatic smooth muscle contraction in the rabbit.
Topics: Adrenergic alpha-Antagonists; Animals; Arginine; Arteriosclerosis; Blood Flow Velocity; Cyclic GMP; Doxazosin; Electric Stimulation; Iliac Artery; In Vitro Techniques; Ischemia; Laser-Doppler Flowmetry; Male; Muscle Contraction; Muscle, Smooth; Nitric Oxide; Phosphodiesterase Inhibitors; Piperazines; Prostate; Purines; Rabbits; Sildenafil Citrate; Sulfones | 2003 |
Cardiac enkephalins attenuate vagal bradycardia: interactions with NOS-1-cGMP systems in canine sinoatrial node.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Bradycardia; Cyclic GMP; Dogs; Dose-Response Relationship, Drug; Enkephalin, Methionine; Enzyme Inhibitors; Indazoles; Methacholine Chloride; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Parasympathomimetics; Penicillamine; Phosphodiesterase Inhibitors; Sinoatrial Node; Vagus Nerve | 2003 |
Protein kinase Cbeta selective inhibitor LY333531 attenuates diabetic hyperalgesia through ameliorating cGMP level of dorsal root ganglion neurons.
Topics: Animals; Arginine; Cyclic GMP; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Enzyme Inhibitors; Ganglia, Spinal; Immunohistochemistry; Indoles; Male; Maleimides; NAV1.9 Voltage-Gated Sodium Channel; Neuropeptides; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nociceptors; Protein Kinase C; Protein Kinase C beta; Rats; Rats, Sprague-Dawley; Sodium Channels; Tetrodotoxin | 2003 |
Combining lisinopril and l-arginine slows disease progression and reduces endothelin-1 in passive Heymann nephritis.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Blood Pressure; Cyclic GMP; Disease Progression; Drug Combinations; Endothelin-1; Glomerulonephritis; Kidney; Lisinopril; Male; Proteinuria; Rats; Rats, Sprague-Dawley; Systole | 2003 |
Plasma membrane calcium ATPase overexpression in arterial smooth muscle increases vasomotor responsiveness and blood pressure.
Topics: Animals; Aorta; Arginine; Blood Pressure; Calcium; Calcium-Transporting ATPases; Cation Transport Proteins; Cell Line; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Doxycycline; Enzyme Inhibitors; Female; Gene Expression Regulation, Enzymologic; Genotype; Humans; In Vitro Techniques; Isoenzymes; Male; Mesenteric Arteries; Mice; Mice, Transgenic; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Phenylephrine; Plasma Membrane Calcium-Transporting ATPases; Potassium Chloride; Vasoconstriction; Vasomotor System | 2003 |
Relaxation of rabbit corpus cavernosum by selective activators of voltage-gated sodium channels: role of nitric oxide-cyclic guanosine monophosphate pathway.
Topics: Aconitine; Animals; Arginine; Batrachotoxins; Binding Sites; Cyclic GMP; Guanylate Cyclase; In Vitro Techniques; Insect Proteins; Isometric Contraction; Male; Marine Toxins; Muscle, Smooth; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxocins; Penile Erection; Penis; Piperazines; Purines; Rabbits; Scorpion Venoms; Sildenafil Citrate; Sodium Channel Agonists; Sodium Channel Blockers; Sodium Channels; Sulfones; Veratridine | 2003 |
Arginase reciprocally regulates nitric oxide synthase activity and contributes to endothelial dysfunction in aging blood vessels.
Topics: Aging; Animals; Arginase; Arginine; Blood Vessels; Cyclic GMP; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Nitric Oxide Synthase; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Vasodilation; Vasodilator Agents | 2003 |
[Therapy of erectile dysfunction in 2005].
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Arginine; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Drugs, Investigational; Enzyme Activation; Erectile Dysfunction; Forecasting; Guanylate Cyclase; Humans; Intracellular Signaling Peptides and Proteins; Male; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Protein Serine-Threonine Kinases; rho-Associated Kinases | 2003 |
Constitutive activation and uncoupling of the atrial natriuretic peptide receptor by mutations at the dimer interface. Role of the dimer structure in signalling.
Topics: Animals; Arginine; COS Cells; Crystallography, X-Ray; Cyclic GMP; Diethyl Pyrocarbonate; Dimerization; DNA, Complementary; Histidine; Hydrogen Bonding; Kinetics; Mass Spectrometry; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Peptides; Protein Conformation; Receptors, Atrial Natriuretic Factor; Signal Transduction; Time Factors; Transfection; Trypsin; Tryptophan | 2004 |
Activation of nitric oxide-cyclic guanosine monophosphate signaling in kidney by extracorporeal shock wave therapy.
Topics: Animals; Arginine; Cyclic GMP; Enzyme Inhibitors; Kidney; Lithotripsy; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Oxadiazoles; Quinoxalines; Rabbits; Signal Transduction | 2003 |
The L-arginine/nitric oxide/cyclic-GMP pathway apparently mediates the peripheral antihyperalgesic action of fentanyl in rats.
Topics: Analgesics, Opioid; Animals; Arginine; Cyclic GMP; Dinoprostone; Dose-Response Relationship, Drug; Fentanyl; Formaldehyde; Hyperalgesia; Male; Nitric Oxide; Nitric Oxide Synthase; Oxytocics; Rats; Rats, Wistar | 2003 |
Reduction in [D-Ala2, NMePhe4, Gly-ol5]enkephalin-induced peripheral antinociception in diabetic rats: the role of the L-arginine/nitric oxide/cyclic guanosine monophosphate pathway.
Topics: Analgesics, Opioid; Animals; Arginine; Blood Glucose; Cyclic GMP; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enzyme Inhibitors; Formaldehyde; Guanylate Cyclase; Male; Methylene Blue; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Pain; Pain Measurement; Rats; Rats, Wistar | 2004 |
Stimulatory effect of leptin on nitric oxide production is impaired in dietary-induced obesity.
Topics: Animals; Arginine; Blood Pressure; Cyclic GMP; Leptin; Male; Nitric Oxide; Nitric Oxide Donors; Obesity; Random Allocation; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine | 2003 |
Participation of the NO-cyclic GMP pathway in rofecoxib-induced antinociception.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Cyclic GMP; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Guanylate Cyclase; Isoenzymes; Lactones; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Oxadiazoles; Pain; Prostaglandin-Endoperoxide Synthases; Quinoxalines; Rats; Rats, Wistar; Sulfones; Uric Acid | 2003 |
Production and role of extracellular guanosine cyclic 3', 5' monophosphate in sodium uptake in human proximal tubule cells.
Topics: Arginine; Biological Transport; Cells, Cultured; Cyclic GMP; Enzyme Inhibitors; Female; Humans; Hypertension; Ion Transport; Kidney Tubules, Proximal; Male; Middle Aged; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Probenecid; S-Nitroso-N-Acetylpenicillamine; Sodium | 2004 |
Augmentation of the NO-cGMP cascade induces anxiogenic-like effect in mice.
Topics: Animals; Anxiety; Arginine; Behavior, Animal; Carbolines; Cyclic GMP; Disease Models, Animal; Drug Therapy, Combination; Injections, Intraperitoneal; Male; Maze Learning; Mice; Motor Activity; Nitric Oxide; Piperazines; Purines; Sildenafil Citrate; Sulfones; Time Factors | 2003 |
Cytomegalovirus infection impairs the nitric oxide synthase pathway: role of asymmetric dimethylarginine in transplant arteriosclerosis.
Topics: Amidohydrolases; Arginine; Cardiovascular Diseases; Cells, Cultured; Coronary Angiography; Coronary Artery Disease; Cyclic GMP; Cytomegalovirus Infections; Endothelium, Vascular; Female; Heart Transplantation; Humans; Male; Middle Aged; Nitric Oxide Synthase; Nitrites; Oxidative Stress; Risk Factors; Signal Transduction | 2004 |
Participation of the L-arginine-nitric oxide-cyclic GMP-ATP-sensitive K+ channel cascade in the antinociceptive effect of rofecoxib.
Topics: Adenosine Triphosphate; Analgesics; Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Lactones; Nitric Oxide; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; Signal Transduction; Sulfones | 2004 |
Zileuton induces hemoglobin F synthesis in erythroid progenitors: role of the L-arginine-nitric oxide signaling pathway.
Topics: Anemia, Sickle Cell; Arginine; Case-Control Studies; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Erythroid Precursor Cells; Fetal Hemoglobin; Gene Expression Regulation; Humans; Hydroxyurea; K562 Cells; Nitric Oxide; Nitric Oxide Synthase; Signal Transduction | 2004 |
Peripheral analgesic blockade of hypernociception: activation of arginine/NO/cGMP/protein kinase G/ATP-sensitive K+ channel pathway.
Topics: Adenosine Triphosphate; Analgesics; Animals; Arginine; Carbazoles; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dinoprostone; Indoles; Male; Nitric Oxide; Nociceptors; omega-N-Methylarginine; Oxadiazoles; Potassium Channels; Quinoxalines; Rats; Rats, Wistar; Signal Transduction | 2004 |
L-arginine and phosphodiesterase (PDE) inhibitors counteract fibrosis in the Peyronie's fibrotic plaque and related fibroblast cultures.
Topics: Animals; Apoptosis; Arginine; Blotting, Western; Cyclic GMP; Enzyme Inhibitors; Fibrosis; Humans; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Penile Induration; Penis; Pentoxifylline; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Piperazines; Purines; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sildenafil Citrate; Sulfones | 2003 |
Upregulation of endothelial nitric oxide synthase in rat aorta after ingestion of fish oil-rich diet.
Topics: Animals; Aorta; Arginine; Citrulline; Cyclic GMP; Dietary Fats, Unsaturated; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Fish Oils; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxidoreductases; Rats; Rats, Sprague-Dawley; RNA, Messenger; Superoxides; Up-Regulation | 2004 |
Cobalt-60 gamma radiation increased the nitric oxide generation in cultured rat vascular smooth muscle cells.
Topics: Animals; Aorta, Thoracic; Arginine; Cells, Cultured; Cobalt Radioisotopes; Cyclic GMP; DNA Primers; DNA, Complementary; Gamma Rays; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Up-Regulation | 2004 |
Mechanisms involved in the antiplatelet activity of 8-methyl-4-(1-piperazinyl)-7-(3-pyridinylmethoxy)-2H-1-benzopyran-2-one (RC414).
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Arginine; Blood Platelets; Calcium; Chromones; Cyclic AMP; Cyclic GMP; Drug Interactions; Humans; In Vitro Techniques; Nitric Oxide; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Kinase C; Thrombin | 2004 |
Involvement of NO/cGMP pathway in toluene-induced locomotor hyperactivity in female rats.
Topics: Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Guanylate Cyclase; Hyperkinesis; Injections, Intraperitoneal; Motor Activity; Nerve Tissue Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitroprusside; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Signal Transduction; Toluene | 2004 |
Chronic l-arginine treatment reduces vascular smooth muscle cell hypertrophy through cell cycle modifications in spontaneously hypertensive rats.
Topics: Animals; Arginine; Carotid Arteries; Cell Cycle; Cell Division; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Enzyme Induction; G1 Phase; Hypertrophy; Male; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide Synthase; Nitrites; Ploidies; Rats; Rats, Inbred SHR; Time Factors | 2004 |
Roles of endogenous nitric oxide synthase inhibitors and endothelin-1 for regulating myometrial contractions during gestation in the rat.
Topics: Animals; Arginine; Cyclic GMP; Endothelin-1; Enzyme Inhibitors; Female; Isoenzymes; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Uterine Contraction | 2004 |
Modulation of iNOS activity in age-related cardiac dysfunction.
Topics: Aging; Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluorescent Antibody Technique, Indirect; Guanidines; Isothiuronium; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; RNA, Messenger; Ventricular Dysfunction, Left | 2004 |
Nitric oxide modulates local reflexes of the tailfan of the crayfish.
Topics: Analysis of Variance; Animals; Arginine; Astacoidea; Cyclic GMP; Cyclic N-Oxides; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Female; Free Radical Scavengers; Imidazoles; In Vitro Techniques; Male; Muscles; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Penicillamine; Picolines; Quinoxalines; Reflex; Thionucleotides | 2004 |
Effect of short-term administration of high dose L-arginine on restenosis after percutaneous transluminal coronary angioplasty.
Topics: Aged; Angina Pectoris; Angioplasty, Balloon, Coronary; Arginine; Coronary Restenosis; Cyclic GMP; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Myocardial Infarction; Nitric Oxide | 2004 |
Biochemical responses of healthy subjects during dietary supplementation with L-arginine.
Topics: Arginine; Biological Availability; Blood; Blood Glucose; Citrulline; Cyclic GMP; Dietary Supplements; Dose-Response Relationship, Drug; Female; Glycine; Humans; Insulin; Lysine; Male; Ornithine | 2004 |
Inhibition of endothelial nitric oxide generation by low-density lipoprotein is partially prevented by L-arginine and L-ascorbate.
Topics: Adult; Arginine; Ascorbic Acid; Cyclic GMP; Diabetes Mellitus, Type 2; Endothelial Cells; Female; Free Radical Scavengers; Humans; Lipoproteins, LDL; Male; Middle Aged; Nitric Oxide | 2004 |
No hemoglobin but NO: the icefish (Chionodraco hamatus) heart as a paradigm.
Topics: Animals; Antarctic Regions; Arginine; Cardiotonic Agents; Cell Respiration; Cyclic GMP; Electrochemistry; Fluorescent Antibody Technique; Molsidomine; Myocardial Contraction; Myocardium; NADH Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Oceans and Seas; Ornithine; Perciformes | 2004 |
Peripheral involvement of the nitric oxide-cGMP pathway in the indomethacin-induced antinociception in rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Chronic Disease; Cyclic GMP; Disease Models, Animal; Enzyme Inhibitors; Female; Gout; Indomethacin; Nerve Tissue Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitroprusside; Pain; Pain Measurement; Peripheral Nervous System; Rats; Rats, Wistar; Signal Transduction; Uric Acid | 2004 |
eNOS, nNOS, cGMP and protein kinase G mediate the inhibitory effect of pancreastatin, a chromogranin A-derived peptide, on growth and proliferation of hepatoma cells.
Topics: Aminoquinolines; Animals; Arginine; Calcium; Carbazoles; Carcinoma, Hepatocellular; Cell Enlargement; Cell Proliferation; Chromogranin A; Chromogranins; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; DNA; Enzyme Inhibitors; Guanylate Cyclase; Indoles; Isoenzymes; Leucine; Liver; MAP Kinase Signaling System; Nerve Tissue Proteins; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Ornithine; Pancreatic Hormones; Peptides; Phospholipase C beta; Protein Isoforms; Rats; Receptors, Atrial Natriuretic Factor; Spermidine; Thymidine; Time Factors; Type C Phospholipases | 2005 |
A calcium channel blocker, benidipine, improves cell membrane fluidity in human subjects via a nitric oxide-dependent mechanism. An electron paramagnetic resonance investigation.
Topics: Aged; Arginine; Calcium Channel Blockers; Cell Membrane; Cyclic GMP; Dihydropyridines; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Erythrocytes; Female; Hemorheology; Humans; Male; Membrane Fluidity; Middle Aged; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Penicillamine; Viscosity | 2004 |
Estimation of EDRF and nitric oxide release using [3H]GTP-labeled human platelets.
Topics: Animals; Arginine; Biological Assay; Blood Platelets; Bradykinin; Cattle; Cell Count; Cells, Cultured; Coculture Techniques; Cyclic GMP; Drug Interactions; Endothelium-Dependent Relaxing Factors; Endothelium, Vascular; Guanosine Triphosphate; Humans; Nitric Oxide; Nitroprusside; Superoxide Dismutase; Tritium | 1995 |
Chronic L-arginine supplementation improves endothelial cell vasoactive functions in hypercholesterolemic and atherosclerotic monkeys.
Topics: Animals; Arginine; Cholesterol, Dietary; Coronary Artery Disease; Cyclic GMP; Diet, Atherogenic; Endothelium, Vascular; Hypercholesterolemia; Lipid Peroxidation; Macaca mulatta; Male; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Superoxides | 2005 |
Plasma L-arginine and metabolites of nitric oxide synthase in patients with left-to-right shunt after intracardiac repair.
Topics: Adolescent; Adult; Arginine; Cardiopulmonary Bypass; Child; Child, Preschool; Cyclic GMP; Female; Heart Defects, Congenital; Humans; Hypertension, Pulmonary; Infant; Male; Nitric Oxide Synthase | 2005 |
Pathological implications of iNOS expression in central white matter: an ex vivo study of optic nerves from rats with experimental allergic encephalomyelitis.
Topics: 1-Methyl-3-isobutylxanthine; Action Potentials; Animals; Arginine; Biomarkers; CD11b Antigen; CD2 Antigens; Cyclic GMP; DEET; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Encephalomyelitis, Autoimmune, Experimental; Female; Guanylate Cyclase; Guinea Pigs; Hydrazines; Immunohistochemistry; Macrophages; Microscopy, Electron, Transmission; Myelin Basic Protein; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Optic Chiasm; Optic Nerve; Ornithine; Phosphodiesterase Inhibitors; Rats; Rats, Inbred Lew; Time Factors | 2005 |
Nomega-hydroxy-L-arginine homologues and hydroxylamine as nitric oxide-dependent vasorelaxant agents.
Topics: Animals; Aorta, Thoracic; Arginine; Cyclic GMP; Cyclic N-Oxides; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; Hydroxylamine; Imidazoles; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Signal Transduction; Vasodilation; Vasodilator Agents | 2005 |
Reduction of ventricular hypertrophy and fibrosis in spontaneously hypertensive rats by L-arginine.
Topics: Animals; Aorta, Thoracic; Arginine; Cardiomegaly; Cyclic GMP; Endomyocardial Fibrosis; Heart Rate; Hypertension; Nitric Oxide; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Systole; Vasodilation | 2005 |
Dietary arginine supplementation attenuates renal damage after relief of unilateral ureteral obstruction in rats.
Topics: Animals; Arginine; Cyclic GMP; Dietary Supplements; Enzyme Inhibitors; Fibroblasts; Fibrosis; Glomerular Filtration Rate; In Situ Nick-End Labeling; Kidney; Macrophages; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Organ Size; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta; Transforming Growth Factor beta1; Ureteral Obstruction | 2005 |
Possible involvement of the spinal nitric oxide/cGMP pathway in vincristine-induced painful neuropathy in mice.
Topics: Analysis of Variance; Animals; Arginine; Blotting, Western; Cyclic GMP; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Injections, Spinal; Male; Mice; Mice, Inbred ICR; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Pain; Pain Measurement; Quinoxalines; Reaction Time; Spinal Cord; Time Factors; Vincristine | 2005 |
A switch 3 point mutation in the alpha subunit of transducin yields a unique dominant-negative inhibitor.
Topics: Aluminum Compounds; Animals; Arginine; Catalysis; Cattle; Chromatography, High Pressure Liquid; Cyclic GMP; Dose-Response Relationship, Drug; Fluorides; Genes, Dominant; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Models, Biological; Models, Molecular; Mutation; Nucleotides; Point Mutation; Protein Conformation; Recombinant Fusion Proteins; Recombinant Proteins; Retina; Rhodopsin; Signal Transduction; Spectrometry, Fluorescence; Time Factors; Transducin; Trypsin | 2005 |
A selective estrogen receptor modulator, tamoxifen, and membrane fluidity of erythrocytes in normotensive and hypertensive postmenopausal women: an electron paramagnetic resonance investigation.
Topics: Aged; Analysis of Variance; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Drug Synergism; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Erythrocyte Membrane; Erythrocytes; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Humans; Hypertension; Membrane Fluidity; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Postmenopause; S-Nitroso-N-Acetylpenicillamine; Selective Estrogen Receptor Modulators; Tamoxifen | 2005 |
Initiation of remote microvascular preconditioning requires K(ATP) channel activity.
Topics: Adenosine; Animals; Arginine; Arterioles; ATP-Binding Cassette Transporters; Bradykinin; Cricetinae; Cyclic GMP; Decanoic Acids; Diazoxide; Hydroxy Acids; Ischemic Preconditioning; KATP Channels; Male; Mesocricetus; Microcirculation; Nitric Oxide Donors; Nitroprusside; Pinacidil; Potassium Channels, Inwardly Rectifying; Signal Transduction; Vasodilation | 2006 |
delta-Opioid receptor agonist SNC80 elicits peripheral antinociception via delta(1) and delta(2) receptors and activation of the l-arginine/nitric oxide/cyclic GMP pathway.
Topics: Analgesics; Animals; Arginine; Benzamides; Benzylidene Compounds; Cyclic GMP; Dinoprostone; Enzyme Inhibitors; Hyperalgesia; Male; Naltrexone; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Piperazines; Rats; Receptors, Opioid, delta | 2005 |
l-Citrulline and l-arginine supplementation retards the progression of high-cholesterol-diet-induced atherosclerosis in rabbits.
Topics: Animals; Antioxidants; Aorta, Thoracic; Arginine; Arteriosclerosis; Ascorbic Acid; Citrulline; Cyclic AMP Response Element-Binding Protein; Cyclic GMP; Diet, Atherogenic; DNA-Binding Proteins; Endothelium, Vascular; ets-Domain Protein Elk-1; Humans; Male; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Oxidation-Reduction; Proto-Oncogene Proteins; Rabbits; Superoxides; Transcription Factors; Vasodilation; Vitamin E | 2005 |
Involvement of nitric oxide-cGMP pathway in the antidepressant-like effects of adenosine in the forced swimming test.
Topics: Adenosine; Animals; Antidepressive Agents; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Injections, Intraventricular; Male; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones; Swimming | 2005 |
Effects of nutritional status on the L-arginine-nitric oxide pathway in platelets from hemodialysis patients.
Topics: Adult; Aged; Amino Acids; Arginine; Blood Platelets; Cyclic GMP; Female; Humans; Kidney Failure, Chronic; Male; Malnutrition; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Nutritional Status; Platelet Aggregation; Renal Dialysis; Tumor Necrosis Factor-alpha; Uremia | 2005 |
Hemodynamic effects of combined sildenafil and L-arginine during acute pulmonary embolism-induced pulmonary hypertension.
Topics: Acute Disease; Analysis of Variance; Animals; Arginine; Blood Pressure; Cyclic GMP; Dogs; Female; Heart Rate; Hypertension, Pulmonary; Infusions, Intravenous; Male; Nitrates; Nitrites; Piperazines; Pulmonary Artery; Pulmonary Embolism; Purines; Respiration; Sildenafil Citrate; Sulfones; Time Factors; Vasodilator Agents | 2005 |
Selective iNOS inhibitor, ONO1714 successfully retards the development of high-cholesterol diet induced atherosclerosis by novel mechanism.
Topics: Amidines; Animals; Aorta, Thoracic; Arginine; Atherosclerosis; Blotting, Western; Cholesterol, Dietary; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Heterocyclic Compounds, 2-Ring; Immunohistochemistry; Macrophages; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Rabbits; Reactive Oxygen Species; RNA, Messenger; Up-Regulation; Vasodilation | 2006 |
L-Arginine-NO-cGMP signaling following acute liver injury in the rat.
Topics: Animals; Arginine; Carbon Tetrachloride; Cyclic GMP; Liver; Liver Regeneration; Male; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; RNA, Messenger; Signal Transduction | 2005 |
Evidence for the involvement of L-arginine-nitric oxide-cyclic guanosine monophosphate pathway in the antidepressant-like effect of memantine in mice.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Arginine; Cyclic GMP; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Female; Immobility Response, Tonic; Male; Memantine; Mice; Nitric Oxide; Nitric Oxide Donors; Nitroarginine; Penicillamine; Piperazines; Purines; Sildenafil Citrate; Sulfones; Swimming | 2006 |
Citrulline, Viagra and BiDil--bad medicine.
Topics: Adult; Arginine; Chronic Disease; Citrulline; Cyclic GMP; Endothelium, Vascular; Erectile Dysfunction; Humans; Hypertension, Pulmonary; Infant; Male; Marketing; Nitric Oxide; Piperazines; Purines; Sildenafil Citrate; Sulfones; Vasodilator Agents | 2005 |
Endurance training reduces circulating asymmetric dimethylarginine and myeloperoxidase levels in persons at risk of coronary events.
Topics: Adult; Aged; Arginine; Cardiovascular Diseases; Cyclic GMP; Exercise; Female; Humans; Male; Middle Aged; Peroxidase; Risk Factors | 2005 |
Estrogen replacement effectively improves the accelerated intimal hyperplasia following balloon injury of carotid artery in the ovariectomized rats.
Topics: Animals; Arginine; Carotid Arteries; Catheterization; Cyclic GMP; Estradiol; Estrogen Replacement Therapy; Female; Follicle Stimulating Hormone; Hyperplasia; Immunohistochemistry; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Ovariectomy; Rats; Rats, Sprague-Dawley; Tunica Intima; Vasodilation | 2006 |
Rewarding properties of sildenafil citrate in mice: role of the nitric oxide-cyclic GMP pathway.
Topics: Animals; Arginine; Conditioning, Psychological; Cyclic GMP; Dose-Response Relationship, Drug; Guanylate Cyclase; Male; Methylene Blue; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phosphodiesterase Inhibitors; Piperazines; Purines; Reward; Sildenafil Citrate; Sulfones | 2006 |
The proconvulsant effect of sildenafil in mice: role of nitric oxide-cGMP pathway.
Topics: Animals; Arginine; Bicuculline; Cyclic GMP; Dose-Response Relationship, Drug; Male; Methylene Blue; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Pentylenetetrazole; Phosphodiesterase Inhibitors; Piperazines; Purines; Seizures; Signal Transduction; Sildenafil Citrate; Sulfones | 2006 |
Reduction of myocardial infarct size by tetrahydrobiopterin: possible involvement of mitochondrial KATP channels activation through nitric oxide production.
Topics: Animals; Anti-Arrhythmia Agents; Arginine; Biopterins; Cyclic GMP; Decanoic Acids; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydroxy Acids; Male; Malondialdehyde; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitrites; Potassium Channels; Rats; Rats, Sprague-Dawley | 2006 |
A single P-loop glutamate point mutation to either lysine or arginine switches the cation-anion selectivity of the CNGA2 channel.
Topics: Amino Acid Sequence; Anions; Arginine; Cations; Cell Line; Cell Membrane Permeability; Cyclic GMP; Cyclic Nucleotide-Gated Cation Channels; Glutamates; Humans; Ion Channels; Lysine; Membrane Potentials; Molecular Sequence Data; Point Mutation; Protein Structure, Secondary | 2006 |
L-arginine chlorination results in the formation of a nonselective nitric-oxide synthase inhibitor.
Topics: Animals; Arginine; Cyclic GMP; Enzyme Inhibitors; Hypochlorous Acid; Male; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasodilation | 2006 |
Neuronal nitric oxide synthase (nNOS) modulates the JNK1 activity through redox mechanism: a cGMP independent pathway.
Topics: Animals; Anisomycin; Arginine; Cells, Cultured; Cyclic GMP; Enzyme Activation; Humans; MAP Kinase Kinase 4; MAP Kinase Kinase Kinase 1; Mitogen-Activated Protein Kinase 8; Mutation; NADPH Dehydrogenase; Neurons; Nitric Oxide; Nitric Oxide Synthase Type I; Oxidation-Reduction; Rats; S-Nitroso-N-Acetylpenicillamine; Signal Transduction | 2006 |
NO donors inhibit Na,K-ATPase activity by a protein kinase G-dependent mechanism in the nonpigmented ciliary epithelium of the porcine eye.
Topics: Animals; Aqueous Humor; Arginine; Ciliary Body; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitrites; Peroxynitrous Acid; Sodium-Potassium-Exchanging ATPase; Swine | 2006 |
The antinociceptive activity of Muntingia calabura aqueous extract and the involvement of L-arginine/nitric oxide/cyclic guanosine monophosphate pathway in its observed activity in mice.
Topics: Acetic Acid; Analgesics; Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Elaeocarpaceae; Enzyme Inhibitors; Guanylate Cyclase; Male; Methylene Blue; Mice; Mice, Inbred BALB C; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Pain; Pain Measurement; Plant Extracts; Plant Leaves; Signal Transduction | 2006 |
Cortical feedback to the thalamus is selectively enhanced by nitric oxide.
Topics: Animals; Animals, Newborn; Arginine; Cerebral Cortex; Cyclic GMP; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Feedback; Ferrets; Geniculate Bodies; In Vitro Techniques; Male; N-Methylaspartate; Neural Pathways; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Penicillamine; Superoxide Dismutase; Synaptic Transmission; Triazoles | 2006 |
Peripheral antinociceptive effect of pertussis toxin: activation of the arginine/NO/cGMP/PKG/ ATP-sensitive K channel pathway.
Topics: Adenosine Triphosphate; Analgesia; Analgesics; Animals; Arginine; Bucladesine; Carbazoles; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dinoprostone; Enzyme Inhibitors; Ganglia, Spinal; Glyburide; Indoles; KATP Channels; Male; Neurons; Nitric Oxide; omega-N-Methylarginine; Oxadiazoles; Pain; Pain Measurement; Pertussis Toxin; Potassium Channels, Inwardly Rectifying; Quinoxalines; Rats; Rats, Wistar; Signal Transduction; Tolbutamide | 2006 |
Low nitric oxide bioavailability contributes to the genesis of experimental cerebral malaria.
Topics: Alkenes; Animals; Arginine; Blood Pressure; Capillary Permeability; Cyclic GMP; Hemoglobins; Malaria, Cerebral; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Animal; Models, Biological; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; Plasmodium berghei; Tissue Distribution | 2006 |
Elevated endogenous nitric oxide increases Ca2+ flux via L-type Ca2+ channels by S-nitrosylation in rat hippocampal neurons during severe hypoxia and in vitro ischemia.
Topics: Animals; Arginine; Brain Ischemia; Calcium; Calcium Channels, L-Type; Cell Hypoxia; Cells, Cultured; Cyclic GMP; Electrophysiology; Enzyme Inhibitors; Fura-2; Hippocampus; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxygen; Rats; Rats, Sprague-Dawley; S-Nitrosothiols | 2007 |
Nitric oxide pathway activation and impaired red blood cell deformability with hypercholesterolemia.
Topics: Animals; Arginine; Blood Chemical Analysis; Cyclic GMP; Enzyme Inhibitors; Erythrocytes; Female; Hypercholesterolemia; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Rabbits | 2006 |
Involvement of NO/cGMP signaling in the apoptotic and anti-angiogenic effects of beta-lapachone on endothelial cells in vitro.
Topics: Angiogenesis Inhibitors; Apoptosis; Arginine; Calcium; Calpain; Caspases; Cell Line; Cell Survival; Chelating Agents; Cyclic GMP; Dose-Response Relationship, Drug; Egtazic Acid; Endothelial Cells; Enzyme Activation; Enzyme Inhibitors; Humans; Leupeptins; Membrane Potential, Mitochondrial; Naphthoquinones; Neovascularization, Physiologic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type III; Oligopeptides; Signal Transduction; Time Factors | 2007 |
Nitric oxide decreases ammonium release in tadpoles of the clawed frog, Xenopus laevis, Daudin.
Topics: Animals; Arginine; Cyclic GMP; Enzyme Inhibitors; Epidermis; Fluorescein; Gills; Handling, Psychological; Immunohistochemistry; Indicators and Reagents; Larva; Mitochondria; NADPH Dehydrogenase; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; omega-N-Methylarginine; Quaternary Ammonium Compounds; S-Nitroso-N-Acetylpenicillamine; Stress, Physiological; Xenopus laevis | 2007 |
Conditional neuronal nitric oxide synthase overexpression impairs myocardial contractility.
Topics: Animals; Arginine; Caffeine; Calcium; Calcium Channels, L-Type; Calcium Signaling; Cell Size; Cells, Cultured; Citrulline; Cyclic GMP; Doxycycline; Enzyme Induction; Ion Channel Gating; Mice; Mice, Transgenic; Myocardial Contraction; Myocytes, Cardiac; Nitric Oxide Synthase Type I; Ornithine; Protein Interaction Mapping; Recombinant Fusion Proteins; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Stroke Volume; Ultrasonography; Ventricular Dysfunction, Left | 2007 |
Roles of accumulated endogenous nitric oxide synthase inhibitors, enhanced arginase activity, and attenuated nitric oxide synthase activity in endothelial cells for pulmonary hypertension in rats.
Topics: Amidohydrolases; Animals; Arginase; Arginine; Cyclic GMP; Endothelial Cells; Enzyme Activation; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Isometric Contraction; Lung; Male; Monocrotaline; Nitric Oxide; Nitric Oxide Synthase Type III; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Vasoconstriction | 2007 |
Does nitric oxide modulate transmitter release at the mammalian neuromuscular junction?
Topics: Animals; Arginine; Cyclic GMP; Diaphragm; Drug Synergism; Electric Stimulation; Enzyme Activators; Exocytosis; Guanylate Cyclase; Indazoles; Intracellular Fluid; Motor Endplate; Neuromuscular Junction; Neurotransmitter Agents; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Phrenic Nerve; Purinergic P1 Receptor Antagonists; Quinoxalines; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Sodium Nitrite; Xanthines | 2007 |
The ADMA/DDAH pathway is a critical regulator of endothelial cell motility.
Topics: Actin Cytoskeleton; Amidohydrolases; Animals; Arginine; cdc42 GTP-Binding Protein; Cell Movement; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cytoskeleton; Endothelial Cells; Enzyme Activation; Focal Adhesions; Lung; Mice; Mice, Knockout; Neovascularization, Physiologic; rac1 GTP-Binding Protein; rhoA GTP-Binding Protein; rhoB GTP-Binding Protein; Signal Transduction; Stress Fibers; Swine | 2007 |
Intrathecal cGMP elicits pressor responses and maintains mean blood pressure during haemorrhage in anaesthetized rats.
Topics: Anesthesia; Animals; Arginine; Blood Pressure; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Heart Rate; Hemorrhage; Injections, Spinal; Nitric Oxide; Oxadiazoles; Pressoreceptors; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Soluble Guanylyl Cyclase; Sympathetic Nervous System | 2007 |
Involvement of L-arginine-nitric oxide-cyclic guanosine monophosphate pathway in the antidepressant-like effect of venlafaxine in mice.
Topics: Analysis of Variance; Animals; Antidepressive Agents, Second-Generation; Arginine; Behavior, Animal; Cyclic GMP; Cyclohexanols; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Immobility Response, Tonic; Male; Mice; Motor Activity; Nitric Oxide; Signal Transduction; Swimming; Venlafaxine Hydrochloride | 2007 |
Effect of ocular hypertension on retinal nitridergic pathway activity.
Topics: Amino Acid Transport Systems, Basic; Animals; Anterior Chamber; Arginine; Blotting, Western; Citrulline; Cyclic GMP; Disease Models, Animal; Hyaluronic Acid; Intraocular Pressure; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Ocular Hypertension; Radioimmunoassay; Rats; Rats, Wistar; Retina; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2007 |
Involvement of nitric oxide (NO) signaling pathway in the antidepressant action of bupropion, a dopamine reuptake inhibitor.
Topics: Animals; Antidepressive Agents, Second-Generation; Arginine; Behavior, Animal; Body Temperature; Brain; Bupropion; Cyclic GMP; Depression; Dopamine; Dopamine Uptake Inhibitors; Homovanillic Acid; Male; Mice; Motor Activity; Nitric Oxide; Norepinephrine; Rats; Rats, Wistar; Reserpine; Signal Transduction; Swimming | 2007 |
Possible involvement of L-arginine-nitric oxide (NO)-cyclic guanosine monophosphate (cGMP) signaling pathway in the antidepressant activity of berberine chloride.
Topics: Animals; Antidepressive Agents; Arginine; Behavior, Animal; Berberine; Brain Chemistry; Cyclic GMP; Dose-Response Relationship, Drug; Drug Synergism; Hindlimb Suspension; Indazoles; Injections, Intraperitoneal; Male; Mice; Motor Activity; Neurotransmitter Agents; Nitric Oxide; Piperazines; Purines; Signal Transduction; Sildenafil Citrate; Stress, Psychological; Sulfones; Swimming; Time Factors | 2007 |
Intracerebroventricular administration of nitric oxide-sensitive guanylyl cyclase inhibitors induces catalepsy in mice.
Topics: Animals; Arginine; Behavior, Animal; Catalepsy; Corpus Striatum; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Indazoles; Injections, Intraventricular; Male; Methylene Blue; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Quinoxalines; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Soluble Guanylyl Cyclase; Time Factors | 2007 |
Nitric oxide modulates ionic transport in the isolated intestine of the eel, Anguilla anguilla.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Anguilla; Animals; Arginine; Bicarbonates; Chlorides; Cyclic GMP; Diffusion Chambers, Culture; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Intestinal Absorption; Intestinal Mucosa; Intestines; Membrane Potentials; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Oxadiazoles; Permeability; Quinoxalines; Time Factors | 2007 |
Twenty-four-hour variation of L-arginine/nitric oxide/cyclic guanosine monophosphate pathway demonstrated by the mouse visceral pain model.
Topics: Abdominal Pain; Analgesics; Animals; Arginine; Benzoquinones; Circadian Rhythm; Cyclic GMP; Enzyme Inhibitors; Male; Methylene Blue; Mice; Mice, Inbred Strains; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitrites; Nitroprusside; Pain; Pain Measurement; Signal Transduction | 2007 |
Disruption of NO-cGMP signaling by neonatal hyperoxia impairs relaxation of lung parenchyma.
Topics: Aging; Animals; Animals, Newborn; Arginase; Arginine; Cyclic GMP; Electric Stimulation; Enzyme Inhibitors; Hyperoxia; In Vitro Techniques; Lung; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Signal Transduction | 2007 |
The role of nitric oxide in the effects of ovarian steroids on spontaneous myometrial contractility in rats.
Topics: Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Estradiol; Female; Gene Expression; Gene Expression Profiling; Immunohistochemistry; Myometrium; Neurons; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Ovariectomy; Progesterone; Random Allocation; Rats; Rats, Sprague-Dawley; Uterine Contraction | 2007 |
Thrombospondin-1 stimulates platelet aggregation by blocking the antithrombotic activity of nitric oxide/cGMP signaling.
Topics: Animals; Arginine; Blood Platelets; CD36 Antigens; CD47 Antigen; Cell Adhesion Molecules; Cyclic GMP; Fibrinolytic Agents; Immunologic Capping; Mice; Mice, Knockout; Microfilament Proteins; Nitric Oxide; Peptides; Phosphoproteins; Platelet Adhesiveness; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; rap1 GTP-Binding Proteins; Secretory Vesicles; Shear Strength; Thrombin; Thrombospondin 1 | 2008 |
11,12-Epoxyeicosatrienoic acid activates the L-arginine/nitric oxide pathway in human platelets.
Topics: 8,11,14-Eicosatrienoic Acid; Adult; Arginine; Biological Transport; Blood Platelets; Calcium Signaling; Collagen; Cyclic GMP; Female; Humans; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Tritium | 2008 |
Dopamine (D1) receptor activation and nitrinergic agents influence somatostatin levels in rat retina.
Topics: Animals; Apomorphine; Arginine; Cyclic GMP; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Female; Nitric Oxide; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Retina; Somatostatin; Tissue Culture Techniques | 2008 |
Effects of L-arginine and phosphodiesterase-5 inhibitor, sildenafil, on inflammation and airway responsiveness of sensitized BP2 mice.
Topics: Animals; Arginine; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cyclic GMP; Eosinophilia; Eosinophils; Lung; Male; Methacholine Chloride; Mice; Nitric Oxide; Ovalbumin; Phosphodiesterase 5 Inhibitors; Phosphodiesterase Inhibitors; Piperazines; Plethysmography, Whole Body; Purines; Sildenafil Citrate; Sulfones | 2007 |
Simultaneous assessment of endothelial function, nitric oxide synthase activity, nitric oxide-mediated signaling, and oxidative stress in individuals with and without hypercholesterolemia.
Topics: Adolescent; Adult; Aged; Arginine; Cyclic GMP; Dinoprost; Endothelium, Vascular; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxidative Stress; Sex Factors | 2008 |
Role of the NO/cGMP/K(ATP) pathway in the protective effects of sildenafil against ethanol-induced gastric damage in rats.
Topics: Animals; Arginine; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Diazoxide; Disease Models, Animal; Enzyme Inhibitors; Ethanol; Gastric Mucosa; Glutathione; Glyburide; Guanylate Cyclase; Hemoglobins; KATP Channels; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Peptic Ulcer Hemorrhage; Phosphodiesterase 5 Inhibitors; Phosphodiesterase Inhibitors; Piperazines; Potassium Channel Blockers; Purines; Quinoxalines; Rats; Rats, Wistar; Signal Transduction; Sildenafil Citrate; Stomach Ulcer; Sulfones | 2008 |
Sildenafil reduces alcohol-induced gastric damage: just say 'NO'.
Topics: Animals; Arginine; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Disease Models, Animal; Ethanol; Gastric Mucosa; Glutathione; Guanylate Cyclase; Hemoglobins; KATP Channels; Nitric Oxide; Nitric Oxide Synthase; Peptic Ulcer Hemorrhage; Phosphodiesterase 5 Inhibitors; Phosphodiesterase Inhibitors; Piperazines; Purines; Rats; Signal Transduction; Sildenafil Citrate; Stomach Ulcer; Sulfones | 2008 |
Involvement of the endothelial DDAH/ADMA pathway in nitroglycerin tolerance: the role of ALDH-2.
Topics: Acetylcysteine; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Amidohydrolases; Arginine; Cell Line; Cyclic GMP; Drug Tolerance; Endothelial Cells; Humans; Lipid Peroxides; Nitric Oxide Donors; Nitric Oxide Synthase Type III; Nitroglycerin; Oxidative Stress; Reactive Oxygen Species | 2008 |
Nitric oxide synthesis leads to vascular endothelial growth factor synthesis via the NO/cyclic guanosine 3',5'-monophosphate (cGMP) pathway in human corpus cavernosal smooth muscle cells.
Topics: Arginine; Cyclic GMP; Humans; Imidazoles; Male; Middle Aged; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nitric Oxide; Nitric Oxide Synthase Type III; Penis; Phosphodiesterase Inhibitors; Piperazines; Signal Transduction; Sulfones; Triazines; Vardenafil Dihydrochloride; Vascular Endothelial Growth Factor A; Vasodilator Agents | 2008 |
Possible involvement of nitric oxide (NO) signaling pathway in the antidepressant-like effect of MK-801(dizocilpine), a NMDA receptor antagonist in mouse forced swim test.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Arginine; Cyclic GMP; Dizocilpine Maleate; Dose-Response Relationship, Drug; Mice; Nitric Oxide; Physical Exertion; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Swimming | 2008 |
Circulating endothelial progenitor cells in patients with Eisenmenger syndrome and idiopathic pulmonary arterial hypertension.
Topics: AC133 Antigen; Aged; Antigens, CD; Antigens, CD34; Arginine; Cells, Cultured; Cyclic GMP; Down Syndrome; Eisenmenger Complex; Endothelium, Vascular; Exercise; Female; Flow Cytometry; Glycoproteins; Hematopoietic Stem Cells; Humans; Hypertension, Pulmonary; Inflammation Mediators; Male; Middle Aged; Natriuretic Peptide, Brain; Peptides; Piperazines; Pulmonary Artery; Purines; Sildenafil Citrate; Stem Cells; Sulfones; Vascular Endothelial Growth Factor Receptor-2; Vasodilator Agents | 2008 |
Increase in brain tumor permeability in glioma-bearing rats with nitric oxide donors.
Topics: Administration, Oral; Animals; Arginine; Blood-Brain Barrier; Brain Neoplasms; Capillary Permeability; Citrulline; Cyclic GMP; Drug Delivery Systems; Drug Evaluation, Preclinical; Drug Synergism; Female; Glioma; Hydroxyurea; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Rats; Rats, Inbred F344; Tumor Cells, Cultured | 2008 |
Nitric oxide modulates the frog heart ventricle morphodynamics.
Topics: Animals; Anura; Arginine; Cyclic GMP; Female; Heart Ventricles; In Vitro Techniques; Indazoles; Male; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Perfusion; Serine; Software; Ventricular Function | 2008 |
Participation of the GABA/benzodiazepine receptor and the NO-cyclicGMP pathway in the "antinociceptive-like effects" of diazepam.
Topics: Analgesics; Animals; Arginine; Cyclic GMP; Diazepam; Enzyme Inhibitors; Guanylate Cyclase; Hypnotics and Sedatives; Indazoles; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type I; Pain Measurement; Rats; Rats, Wistar; Receptors, GABA-A; Signal Transduction | 2008 |
Arg97 at the heme-distal side of the isolated heme-bound PAS domain of a heme-based oxygen sensor from Escherichia coli (Ec DOS) plays critical roles in autoxidation and binding to gases, particularly O2.
Topics: Arginine; Carbon Monoxide; Carrier Proteins; Crystallography, X-Ray; Cyclic GMP; Escherichia coli Proteins; Ferric Compounds; Ferrous Compounds; Heme; Iron; Models, Molecular; Mutagenesis, Site-Directed; Nitric Oxide; Oxidation-Reduction; Oxygen; Phosphoric Diester Hydrolases; Protein Binding; Protein Structure, Tertiary; Structure-Activity Relationship | 2008 |
Involvement of L-arginine-nitric oxide-cyclic guanosine monophosphate pathway in the antidepressant-like effect of tramadol in the rat forced swimming test.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Arginine; Behavior, Animal; Cyclic GMP; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Exploratory Behavior; Male; Nitric Oxide; Rats; Rats, Wistar; Signal Transduction; Swimming; Tramadol | 2008 |
Uric acid decreases NO production and increases arginase activity in cultured pulmonary artery endothelial cells.
Topics: Animals; Arginase; Arginine; Boronic Acids; Bradykinin; Calcimycin; Cells, Cultured; Cyclic GMP; Down-Regulation; Endothelial Cells; Enzyme Inhibitors; Kinetics; Nitric Oxide; Nitric Oxide Synthase Type III; Pulmonary Artery; Rats; Swine; Up-Regulation; Urea; Uric Acid; Vasodilation | 2008 |
Antidepressant-like effect of folic acid: Involvement of NMDA receptors and L-arginine-nitric oxide-cyclic guanosine monophosphate pathway.
Topics: Animals; Antidepressive Agents; Arginine; Cyclic GMP; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Female; Folic Acid; Indazoles; Injections, Intraventricular; Male; Methylene Blue; Mice; N-Methylaspartate; Nitric Oxide; Nitric Oxide Donors; Receptors, N-Methyl-D-Aspartate; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; Swimming; Vitamin B Complex | 2008 |
Nitric oxide upregulates dimethylarginine dimethylaminohydrolase-2 via cyclic GMP induction in endothelial cells.
Topics: Amidohydrolases; Animals; Arginine; Carbazoles; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Male; Natriuretic Peptide, C-Type; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitro Compounds; omega-N-Methylarginine; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; RNA, Messenger; S-Nitroso-N-Acetylpenicillamine; Up-Regulation | 2008 |
On the requirement of nitric oxide signaling in the amygdala for consolidation of inhibitory avoidance memory.
Topics: Aminoquinolines; Amygdala; Animals; Anxiety; Arginine; Avoidance Learning; Carbazoles; Cyclic GMP; Enzyme Inhibitors; Exploratory Behavior; Guanylate Cyclase; Male; Maze Learning; Memory; Motor Activity; Nitric Oxide; Nitric Oxide Synthase; Penicillamine; Rats; Rats, Wistar; Signal Transduction | 2009 |
Morphological and physiological study of the cardiac NOS/NO system in the Antarctic (Hb-/Mb-) icefish Chaenocephalus aceratus and in the red-blooded Trematomus bernacchii.
Topics: Animals; Antarctic Regions; Arginine; Blotting, Western; Cyclic GMP; Endocardium; Female; Fluorescent Antibody Technique; Heart Ventricles; Hemodynamics; Male; Molsidomine; Myocardium; NADPH Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Perciformes; Signal Transduction; Stroke Volume | 2009 |
Ligand binding to the Fe(III)-protoporphyrin IX complex of phosphodiesterase from Escherichia coli (Ec DOS) markedly enhances catalysis of cyclic di-GMP: roles of Met95, Arg97, and Phe113 of the putative heme distal side in catalytic regulation and ligand
Topics: Animals; Arginine; Catalysis; Cattle; Cyclic GMP; Escherichia coli Proteins; Ferric Compounds; Heme; Ligands; Methionine; Mutagenesis, Site-Directed; Phenylalanine; Phosphoric Diester Hydrolases; Protein Binding; Protein Structure, Tertiary; Protoporphyrins | 2008 |
Effect of uncoupling endothelial nitric oxide synthase on calcium homeostasis in aged porcine endothelial cells.
Topics: Animals; Arginine; Biopterins; Bradykinin; Calcium; Cells, Cultured; Cellular Senescence; Citrulline; Cyclic GMP; Endothelial Cells; Enzyme Inhibitors; Homeostasis; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type III; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Superoxides; Swine; Time Factors | 2009 |
Nitric oxide reduces flow-induced superoxide production via cGMP-dependent protein kinase in thick ascending limbs.
Topics: Animals; Arginine; Carbazoles; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 2; Enzyme Inhibitors; Guanylate Cyclase; Loop of Henle; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Renal Circulation; Soluble Guanylyl Cyclase; Superoxides | 2009 |
Effect of nitric oxide/cyclic guanosine mono-phosphate pathway on gallbladder relaxant response in bile duct-ligated guinea pigs.
Topics: Amrinone; Animals; Arginine; Bile Ducts; Cyclic GMP; Gallbladder; Guanidines; Guinea Pigs; Hydrazines; In Vitro Techniques; Indazoles; Ligation; Male; Muscle Relaxation; Nitric Oxide; Nitric Oxide Donors; Papaverine; Piperazines; Purines; Sildenafil Citrate; Sulfones | 2009 |
Effects of arginase inhibitors on the contractile and relaxant responses of isolated human penile erectile tissue.
Topics: Adult; Arginase; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Eflornithine; Enzyme Inhibitors; Humans; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Nitric Oxide; Organ Culture Techniques; Penile Erection; Penis; Sex Reassignment Procedures; Young Adult | 2009 |
L-arginine supplementation reduces cardiac noradrenergic neurotransmission in spontaneously hypertensive rats.
Topics: Adrenergic alpha-Agonists; Animals; Arginine; Blood Pressure; Blotting, Western; Cyclic AMP; Cyclic GMP; Guanylate Cyclase; Heart Atria; Heart Rate; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase | 2009 |
Glutamine inhibits ammonia-induced accumulation of cGMP in rat striatum limiting arginine supply for NO synthesis.
Topics: Ammonia; Animals; Arginine; Butyrates; Chromatography, High Pressure Liquid; Corpus Striatum; Cyclic GMP; Diazooxonorleucine; Dose-Response Relationship, Drug; Drug Interactions; Electrochemical Techniques; Glutamine; In Vitro Techniques; Isobutyrates; Male; Microdialysis; Nitric Oxide; Rats; Rats, Sprague-Dawley; Signal Transduction; Time Factors | 2009 |
alpha(2)-Adrenoceptor agonist xylazine induces peripheral antinociceptive effect by activation of the L-arginine/nitric oxide/cyclic GMP pathway in rat.
Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics; Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Hyperalgesia; Male; Nitric Oxide; Nitric Oxide Synthase; Phosphoric Diester Hydrolases; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Soluble Guanylyl Cyclase; Xylazine | 2009 |
Sexual dimorphism in glomerular arginine transport affects nitric oxide generation in old male rats.
Topics: Aging; Animals; Arginine; Biological Transport; Cationic Amino Acid Transporter 1; Cyclic GMP; Female; Kidney Glomerulus; Male; Models, Animal; Nitric Oxide; Nitric Oxide Synthase Type III; Protein Kinase C-alpha; Rats; Rats, Wistar; Sex Characteristics | 2009 |
Regulation of myometrial contractivity during pregnancy in the rat: potential role for DDAH.
Topics: Amidohydrolases; Animals; Arginine; Blotting, Western; Cyclic GMP; Endothelin-1; Female; In Vitro Techniques; Myometrium; Pregnancy; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Uterine Contraction | 2009 |
Gonadal hormones decrease temporomandibular joint kappa-mediated antinociception through a down-regulation in the expression of kappa opioid receptors in the trigeminal ganglia.
Topics: Analgesics; Animals; Arginine; Cyclic GMP; Down-Regulation; Female; Gonadal Hormones; Humans; Male; Nitric Oxide; omega-N-Methylarginine; Oxadiazoles; Pain; Quinoxalines; Rats; Rats, Wistar; Receptors, Opioid, kappa; Sex Characteristics; Signal Transduction; Temporomandibular Joint; Trigeminal Ganglion | 2009 |
Effect of the cGMP pathway on AQP2 expression and translocation: potential implications for nephrogenic diabetes insipidus.
Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Aquaporin 2; Arginine; Arginine Vasopressin; Atrial Natriuretic Factor; Cell Line; Cells, Cultured; Cyclic GMP; Diabetes Insipidus, Nephrogenic; Humans; Kidney Tubules, Collecting; Male; Models, Animal; Morpholines; Protein Biosynthesis; Receptors, Vasopressin; Signal Transduction; Spiro Compounds | 2010 |
PRMT-1 and DDAHs-induced ADMA upregulation is involved in ROS- and RAS-mediated diabetic retinopathy.
Topics: Amidohydrolases; Animals; Arginine; Blotting, Western; Cells, Cultured; Cyclic GMP; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Endothelial Cells; Male; Protein-Arginine N-Methyltransferases; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Renin-Angiotensin System; Up-Regulation | 2009 |
Metabotropic glutamate receptor 5, but not 1, modulates NMDA receptor-mediated activation of neuronal nitric oxide synthase.
Topics: Animals; Arginine; Blotting, Western; Calcium; Cells, Cultured; Cerebellum; Citrulline; Cyclic AMP; Cyclic GMP; Enzyme Activation; Excitatory Amino Acid Agonists; Guanylate Cyclase; N-Methylaspartate; Neurons; Nitrates; Nitric Oxide Synthase Type I; Nitrites; Oncogene Protein v-akt; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate | 2010 |
Oxidative stress, l-arginine-nitric oxide and arginase pathways in platelets from adolescents with anorexia nervosa.
Topics: Adolescent; Anorexia; Arginase; Arginine; Blood Platelets; Cyclic GMP; Female; Humans; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Platelet Aggregation; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2010 |
Heme-arginate suppresses phospholipase C and oxidative stress in the mesenteric arterioles of mineralcorticoid-induced hypertensive rats.
Topics: Animals; Arginine; Arterioles; Blood Pressure; Calcium; Cyclic GMP; Desoxycorticosterone; Dinoprost; Endothelin-1; Heme; Heme Oxygenase (Decyclizing); Hypertension; Inositol 1,4,5-Trisphosphate; Intracellular Fluid; Male; Mesenteric Arteries; Mineralocorticoids; NF-kappa B; Organometallic Compounds; Oxidative Stress; Rats; Rats, Sprague-Dawley; Second Messenger Systems; Sodium Chloride, Dietary; Type C Phospholipases; Up-Regulation | 2010 |
Cyclic GMP as a second messenger in the nitric oxide-mediated conidiation of the mycoparasite Coniothyrium minitans.
Topics: Arginine; Ascomycota; Cyclic AMP; Cyclic GMP; Guanylate Cyclase; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Oxadiazoles; Quinoxalines; Second Messenger Systems; Spores, Fungal | 2010 |
Involvement of nitric oxide-cGMP pathway in the anticonvulsant effects of lithium chloride on PTZ-induced seizure in mice.
Topics: Animals; Anticonvulsants; Arginine; Convulsants; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Indazoles; Injections, Intraperitoneal; Lithium Chloride; Male; Methylene Blue; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pentylenetetrazole; Phosphodiesterase Inhibitors; Piperazines; Purines; Seizures; Sildenafil Citrate; Sulfones; Treatment Outcome | 2010 |
Involvement of L-arginine-nitric oxide-cyclic guanosine monophosphate pathway in the antidepressant-like effect of bis selenide in the mouse tail suspension test.
Topics: Administration, Oral; Animals; Antidepressive Agents; Arginine; Behavior, Animal; Brain; Cyclic GMP; Hindlimb Suspension; Male; Mice; Nitrates; Nitric Oxide; Nitrites; Organoselenium Compounds; Signal Transduction; Swimming | 2010 |
Adenosine analogue-oligo-arginine conjugates (ARCs) serve as high-affinity inhibitors and fluorescence probes of type I cGMP-dependent protein kinase (PKGIalpha).
Topics: Adenosine; Animals; Arginine; Cerebral Arteries; Cyclic GMP; Cyclic GMP-Dependent Protein Kinase Type I; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Fluorescence; Fluorescent Dyes; Humans; Muscle, Smooth, Vascular; Rats; Vasodilation | 2010 |
Characterization of the L-arginine-NO-cGMP pathway in spontaneously hypertensive rat platelets: the effects of pregnancy.
Topics: Animals; Arginine; Blood Platelets; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Female; Guanylate Cyclase; Hypertension; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Platelet Aggregation; Pregnancy; Rats; Rats, Inbred SHR; Rats, Wistar | 2010 |
Protective effect of desipramine, venlafaxine and trazodone against experimental animal model of transient global ischemia: possible involvement of NO-cGMP pathway.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Arginine; Brain; Catalase; Cyclic GMP; Cyclohexanols; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Electron Transport Chain Complex Proteins; Enzyme Inhibitors; Glutathione; Ischemic Attack, Transient; Lipid Peroxidation; Mice; Models, Biological; Nitric Oxide; Signal Transduction; Trazodone; Venlafaxine Hydrochloride | 2010 |
Involvement of NMDA receptors and L-arginine-nitric oxide-cyclic guanosine monophosphate pathway in the antidepressant-like effects of escitalopram in the forced swimming test.
Topics: Animals; Antidepressive Agents, Second-Generation; Arginine; Citalopram; Cyclic GMP; Depression; Exploratory Behavior; Female; Hindlimb Suspension; Mice; Nitric Oxide; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Swimming | 2010 |
Brain-natriuretic peptide and cyclic guanosine monophosphate as biomarkers of myxomatous mitral valve disease in dogs.
Topics: Age Factors; Animals; Arginine; Biomarkers; Cyclic GMP; Dog Diseases; Dogs; Echocardiography; Female; Heart Failure; Heart Valve Diseases; Male; Mitral Valve; Mitral Valve Insufficiency; Natriuretic Peptide, Brain; Peptide Fragments | 2011 |
Zerumbone-induced antinociception: involvement of the L-arginine-nitric oxide-cGMP -PKC-K+ ATP channel pathways.
Topics: Analgesics; Animals; Arginine; Behavior, Animal; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Activation; KATP Channels; Male; Mice; Mice, Inbred ICR; Motor Activity; Nitric Oxide; Pain Measurement; Potassium Channel Blockers; Protein Kinase C; Receptor, Bradykinin B2; Sesquiterpenes; Time Factors; TRPV Cation Channels | 2011 |
Insulin resistance in obesity and metabolic syndrome: is there a connection with platelet l-arginine transport?
Topics: Adolescent; Arginine; Biological Transport; Blood Platelets; Cardiovascular Diseases; Case-Control Studies; Cyclic GMP; Humans; Insulin Resistance; Metabolic Syndrome; Nitric Oxide; Obesity | 2010 |
Role of the spinal cord NO/cGMP pathway in the control of arterial pressure and heart rate.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arginine; Blood Pressure; Cyclic GMP; Dimethyl Sulfoxide; Heart Rate; Male; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Stereoisomerism; Sympathetic Nervous System | 2011 |
Relative similarity within purine nucleotide and ligand structures operating on nitric oxide synthetase, guanylyl cyclase and potassium (K ATP, BK Ca) channels.
Topics: Adenine Nucleotides; Aldosterone; Arginine; Cell Membrane; Cyclic GMP; Dexamethasone; Guanine Nucleotides; Guanylate Cyclase; KATP Channels; Large-Conductance Calcium-Activated Potassium Channels; Ligands; Models, Molecular; Nitric Oxide Synthase; Potassium Channel Blockers; Protein Binding; Signal Transduction | 2011 |
[Effects of simulated microgravity on L-ARG-NO-CGMP pathway of abdominal aorta in rats].
Topics: Animals; Aorta, Abdominal; Arginine; Cyclic GMP; Male; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Weightlessness Simulation | 2006 |
Possible participation of nitric oxide/cyclic guanosine monophosphate/protein kinase C/ATP-sensitive K(+) channels pathway in the systemic antinociception of flavokawin B.
Topics: Analgesics; Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Glyburide; Hypoglycemic Agents; Male; Methylene Blue; Mice; Mice, Inbred ICR; Nitric Oxide; Nitric Oxide Synthase; Pain; Potassium Channels; Protein Kinase C; Signal Transduction | 2011 |
Pharmacological activity of novel 2-hydroxyacetophenone isatin derivatives on cardiac and vascular smooth muscles in rats.
Topics: Acetophenones; Animals; Antipyretics; Arginine; Bradykinin; Cyclic GMP; Heart; Isatin; Male; Muscle Contraction; Muscle, Smooth, Vascular; Rats; Rats, Wistar; Vasodilation; Vasodilator Agents | 2011 |
Lithium chloride disrupts consolidation of morphine-induced conditioned place preference in male mice: the nitric oxide/cyclic GMP signaling pathway.
Topics: Animals; Antimanic Agents; Arginine; Conditioning, Operant; Cyclic GMP; Dose-Response Relationship, Drug; Lithium Chloride; Male; Mice; Morphine; Narcotics; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Phosphodiesterase Inhibitors; Piperazines; Purines; Signal Transduction; Sildenafil Citrate; Sulfones | 2011 |
Increased nitric oxide production in platelets from severe chronic renal failure patients.
Topics: Adenosine Diphosphate; Arginine; Blood Platelets; Case-Control Studies; Collagen; Cyclic GMP; Female; Fibrinogen; Humans; Inflammation; Kidney Failure, Chronic; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Platelet Aggregation | 2011 |
cAMP phosphodiesterase inhibitors increases nitric oxide production by modulating dimethylarginine dimethylaminohydrolases.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Amidohydrolases; Apoptosis; Arginine; Cell Proliferation; Cell Survival; Cells, Cultured; Cyclic GMP; Cytokines; Endothelial Cells; Hemodynamics; Humans; Hypertension, Pulmonary; Naphthyridines; Nitric Oxide; Phosphodiesterase Inhibitors; Promoter Regions, Genetic; Pulmonary Gas Exchange | 2011 |
Protein kinase A-dependent neuronal nitric oxide synthase activation mediates the enhancement of baroreflex response by adrenomedullin in the nucleus tractus solitarii of rats.
Topics: Adrenomedullin; Animals; Arginine; Baroreflex; Bronchodilator Agents; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinase Type I; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Isothiuronium; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Ornithine; Rats; Rats, Sprague-Dawley; S-Nitrosoglutathione; Signal Transduction; Solitary Nucleus | 2011 |
Oral arginine improves linear growth of long bones and the neuroendocrine mechanism.
Topics: Animals; Arginine; Bone Development; Cyclic GMP; Femur; Growth Hormone; Growth Plate; Guanylate Cyclase; Hypothalamo-Hypophyseal System; Male; Nitric Oxide Synthase Type I; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Signal Transduction; Soluble Guanylyl Cyclase; Tibia | 2011 |
Antinociceptive effect of the essential oil of Zingiber zerumbet in mice: possible mechanisms.
Topics: Administration, Oral; Analgesics; Animals; Arginine; Behavior, Animal; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamic Acid; Injections, Intraperitoneal; KATP Channels; Male; Medicine, Traditional; Mice; Mice, Inbred ICR; Neural Pathways; Nitric Oxide; Oils, Volatile; Pain; Pain Measurement; Pain Threshold; Plant Oils; Plant Roots; Plants, Medicinal; Protein Kinase C; Signal Transduction; TRPV Cation Channels; Zingiber officinale | 2011 |
Nitric oxide synthase activity in the abdominal aorta of rats is decreased after 4 weeks of simulated microgravity.
Topics: Acetylcholine; Animals; Aorta, Abdominal; Arginine; Cyclic GMP; Male; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Nitroprusside; Rats; Rats, Sprague-Dawley; Time Factors; Vasodilation; Weightlessness Simulation | 2011 |
Antidepressant-like and neuroprotective effects of Aloysia gratissima: investigation of involvement of L-arginine-nitric oxide-cyclic guanosine monophosphate pathway.
Topics: Administration, Oral; Animals; Antidepressive Agents; Arginine; Behavior, Animal; Blotting, Western; Cell Survival; Cyclic GMP; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamic Acid; Hippocampus; Male; Medicine, Traditional; Mice; Motor Activity; Neuroprotective Agents; Neurotransmitter Agents; Nitric Oxide; Nitric Oxide Synthase Type II; Phosphorylation; Plant Components, Aerial; Plant Extracts; Plants, Medicinal; Proto-Oncogene Proteins c-akt; Signal Transduction; Solvents; Time Factors; Verbenaceae; Water | 2011 |
Effect of exogenous l-arginine and ageing on NO and ET-1 in penile tissue of rat.
Topics: Aging; Animals; Arginine; Cyclic GMP; Endothelin-1; Male; Nitric Oxide; Nitric Oxide Synthase; Penis; Rats; Rats, Wistar | 2011 |
Involvement of nitric oxide-cGMP pathway in the antidepressant-like effect of ascorbic acid in the tail suspension test.
Topics: Animals; Antidepressive Agents; Arginine; Ascorbic Acid; Cyclic GMP; Depression; Disease Models, Animal; Dizocilpine Maleate; Enzyme Inhibitors; Exploratory Behavior; Female; Hindlimb Suspension; Indazoles; Mice; N-Methylaspartate; Nitric Oxide; Oxadiazoles; Piperazines; Purines; Quinoxalines; Signal Transduction; Sildenafil Citrate; Sulfones | 2011 |
Antidepressant-like effect of 1-(7-methoxy-2-methyl-1,2,3,4-tetrahydro-isoquinolin-4-YL)-cyclohexanol, a putative trace amine receptor ligand involves l-arginine-nitric oxide-cyclic guanosine monophosphate pathway.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Arginine; Biogenic Amines; Brain Chemistry; Cyclic GMP; Cyclohexanols; Depression; Guanylate Cyclase; Indazoles; Isoquinolines; Male; Methylene Blue; Mice; Motor Activity; Neurotransmitter Agents; Nitric Oxide; Nitric Oxide Synthase; Phosphodiesterase Inhibitors; Piperazines; Purines; Signal Transduction; Sildenafil Citrate; Sulfones; Swimming | 2011 |
Calreticulin Transacetylase mediated activation of human platelet nitric oxide synthase by acetyl group donor compounds.
Topics: Acetates; Acetylation; Acetyltransferases; Adenosine Diphosphate; Arginine; Blood Platelets; Cells, Cultured; Coumarins; Cyclic GMP; Cytochrome Reductases; Enzyme Inhibitors; Fluoresceins; Humans; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroprusside; Platelet Aggregation; Polyphenols; Structure-Activity Relationship | 2012 |
The antidepressant-like effect of Hedyosmum brasiliense and its sesquiterpene lactone, podoandin in mice: evidence for the involvement of adrenergic, dopaminergic and serotonergic systems.
Topics: 4-Butyrolactone; Analgesics, Opioid; Animals; Antidepressive Agents; Arginine; Cyclic GMP; Cycloheptanes; Dopamine; Drug Interactions; Epinephrine; Ferns; Fluoxetine; Lactones; Locomotion; Male; Mice; Neurotransmitter Agents; Nitric Oxide; Norepinephrine; Plant Extracts; Serotonin; Sesquiterpenes; Swimming | 2012 |
A combination of ischemic preconditioning and allopurinol protects against ischemic injury through a nitric oxide-dependent mechanism.
Topics: Adenosine Deaminase; Alanine Transaminase; Allopurinol; Animals; Arginine; Cyclic GMP; Glutathione; Ischemia; Ischemic Preconditioning; Liver; Male; Mitochondria, Liver; Mitochondrial Swelling; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Organ Size; Rats; Rats, Sprague-Dawley; Theobromine | 2012 |
The peripheral L-arginine-nitric oxide-cyclic GMP pathway and ATP-sensitive K⁺ channels are involved in the antinociceptive effect of crotalphine on neuropathic pain in rats.
Topics: Analgesics; Animals; Arginine; Cyclic GMP; KATP Channels; Male; Neuralgia; Nitric Oxide; Peptides; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, kappa; Signal Transduction | 2012 |
Involvement of the L-arginine/nitric oxide/cyclic guanosine monophosphate pathway in peripheral antinociception induced by N-palmitoyl-ethanolamine in rats.
Topics: Amides; Analgesics; Animals; Arginine; Cyclic GMP; Disease Models, Animal; Endocannabinoids; Ethanolamines; Hyperalgesia; Male; Neural Inhibition; Neural Pathways; Nitric Oxide; Nociception; Palmitic Acids; Rats; Rats, Wistar | 2012 |
Low plasma levels of L-arginine, impaired intraplatelet nitric oxide and platelet hyperaggregability: implications for cardiovascular disease in depressive patients.
Topics: Adult; Amino Acids; Arginine; Blood Platelets; Cardiovascular Diseases; Cyclic GMP; Depressive Disorder, Major; Female; Guanylate Cyclase; Humans; Male; Nitric Oxide; Nitric Oxide Synthase; Platelet Aggregation; Risk Factors | 2012 |
Participation of the NO/cGMP/K+ATP pathway in the antinociception induced by Walker tumor bearing in rats.
Topics: Analgesics; Animals; Arginine; Carcinoma 256, Walker; Carrageenan; Cyclic GMP; Dinoprostone; Hyperalgesia; KATP Channels; Male; Nitric Oxide; Nociception; Oxadiazoles; Pain Measurement; Pain Threshold; Quinoxalines; Rats; Rats, Wistar; Signal Transduction | 2012 |
Attenuated glomerular arginine transport prevents hyperfiltration and induces HIF-1α in the pregnant uremic rat.
Topics: Animals; Arginine; Biological Transport, Active; Blotting, Western; Cationic Amino Acid Transporter 1; Chromatography, High Pressure Liquid; Cyclic GMP; Female; Glomerular Filtration Rate; Hypoxia-Inducible Factor 1, alpha Subunit; Immunoprecipitation; Inulin; Kidney Glomerulus; Nitric Oxide Synthase Type III; p-Aminohippuric Acid; Phosphorylation; Pregnancy; Pregnancy Complications; Protein Kinase C-alpha; Rats; Rats, Wistar; Renal Circulation; Uremia; Vitamin E | 2012 |
Acute atorvastatin treatment exerts antidepressant-like effect in mice via the L-arginine-nitric oxide-cyclic guanosine monophosphate pathway and increases BDNF levels.
Topics: Animals; Antidepressive Agents; Arginine; Atorvastatin; Brain-Derived Neurotrophic Factor; Cyclic GMP; Depression; Heptanoic Acids; Male; Mice; Nitric Oxide; Pyrroles; Signal Transduction | 2013 |
Guanosine produces an antidepressant-like effect through the modulation of NMDA receptors, nitric oxide-cGMP and PI3K/mTOR pathways.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Arginine; Cyclic GMP; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agents; Exploratory Behavior; Female; Freezing Reaction, Cataleptic; Guanosine; Hindlimb Suspension; Immunosuppressive Agents; Male; Mice; N-Methylaspartate; Nitric Oxide; Phosphatidylinositol 3-Kinases; Receptors, N-Methyl-D-Aspartate; Serine; Signal Transduction; Sirolimus; Swimming; TOR Serine-Threonine Kinases | 2012 |
Protective effect of nitric oxide on hepatopulmonary syndrome from ischemia-reperfusion injury.
Topics: Alanine Transaminase; Animals; Arginine; Cyclic GMP; Disease Models, Animal; Enzyme Inhibitors; Hepatorenal Syndrome; Immunohistochemistry; Intercellular Adhesion Molecule-1; Liver; Liver Transplantation; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Reperfusion Injury; Time Factors; Tumor Necrosis Factor-alpha | 2012 |
Modulation of methamphetamine-induced nitric oxide production by neuropeptide Y in the murine striatum.
Topics: Analysis of Variance; Animals; Arginine; Caspase 3; Corpus Striatum; Cyclic GMP; Drug Interactions; Male; Methamphetamine; Mice; Mice, Inbred ICR; Microinjections; Neuropeptide Y; Nitric Oxide Synthase Type II; Peptides; Protein Precursors; Receptors, Neuropeptide Y; RNA, Messenger; Tyrosine | 2012 |
NO/cGMP production is important for the endogenous peripheral control of hyperalgesia during inflammation.
Topics: Animals; Arginine; Carrageenan; Cyclic GMP; Dinoprostone; Hyperalgesia; Inflammation; Male; Nitric Oxide; Pain; Pain Measurement; Pressure; Rats; Rats, Wistar | 2013 |
The role of the NMDA receptors and l-arginine-nitric oxide-cyclic guanosine monophosphate pathway in the antidepressant-like effect of duloxetine in the forced swimming test.
Topics: Animals; Antidepressive Agents; Arginine; Cyclic GMP; Duloxetine Hydrochloride; Female; Mice; Nitric Oxide; Receptors, N-Methyl-D-Aspartate; Swimming; Thiophenes | 2012 |
Defective nitric oxide-cyclic guanosine monophosphate signaling in patients with bipolar disorder: a potential role for platelet dysfunction.
Topics: Adult; Arginase; Arginine; Bipolar Disorder; Blood Platelets; C-Reactive Protein; Cardiovascular Diseases; Case-Control Studies; Comorbidity; Cyclic GMP; Female; Humans; Inflammation; Male; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Signal Transduction; Superoxide Dismutase | 2012 |
Effect of amiloride to retinal toxicity induced by tissue plasminogen activator.
Topics: Amiloride; Analysis of Variance; Animals; Arginine; Cell Death; Cells, Cultured; Cyclic GMP; Enzyme-Linked Immunosorbent Assay; Mice; Retina; Tissue Plasminogen Activator | 2012 |
On the selectivity of neuronal NOS inhibitors.
Topics: Amidines; Animals; Aorta, Thoracic; Arginine; Benzylamines; Cerebellum; Cyclic GMP; Enzyme Inhibitors; Hippocampus; Male; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type I; Ornithine; Rats, Sprague-Dawley | 2013 |
Nitric oxide signaling differentially affects habitat choice by two larval morphs of the sea slug Alderia willowi: mechanistic insight into evolutionary transitions in dispersal strategies.
Topics: Adaptation, Biological; Analysis of Variance; Animal Distribution; Animals; Appetitive Behavior; Arginine; Biological Evolution; California; Cyclic GMP; Cyclic N-Oxides; Dopamine; Ecosystem; Gastropoda; Imidazoles; Larva; Levodopa; Linear Models; Metamorphosis, Biological; Models, Biological; NG-Nitroarginine Methyl Ester; Nitric Oxide; Serotonin; Signal Transduction; Stramenopiles | 2013 |
Involvement of the nitric oxide/cyclic guanylate monophosphate pathway in the pilocarpine-induced seizure model in mice.
Topics: Amidines; Animals; Arginine; Benzylamines; Cyclic GMP; Disease Models, Animal; Enzyme Inhibitors; Guanidines; Guanylate Cyclase; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Pilocarpine; Receptors, Cytoplasmic and Nuclear; Seizures; Soluble Guanylyl Cyclase | 2013 |
Synergistic effects of taurine and L-arginine on attenuating insulin resistance hypertension.
Topics: Animals; Antihypertensive Agents; Arginine; Blood Glucose; Blood Pressure; Cyclic GMP; Drug Synergism; Endothelins; Hypertension; Insulin; Insulin Resistance; Male; Nitric Oxide; Rats; Rats, Wistar; Systole; Taurine | 2013 |
Vasorelaxant effect of Prunus yedoensis bark.
Topics: Animals; Aorta; Arginine; Calcium; Calcium Channel Blockers; Calcium Channels; Cyclic GMP; Endothelium, Vascular; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phenylephrine; Plant Bark; Plant Extracts; Prunus; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasodilator Agents | 2013 |
Peripheral antinociception of a chalcone, flavokawin B and possible involvement of the nitric oxide/cyclic guanosine monophosphate/potassium channels pathway.
Topics: Analgesics; Animals; Arginine; Carrageenan; Chalcone; Cyclic GMP; Disease Models, Animal; Flavonoids; Hyperalgesia; Male; Nitric Oxide; Potassium Channel Blockers; Potassium Channels; Rats; Signal Transduction | 2013 |
Effects of dimethylarginine dimethylaminohydrolase-1 overexpression on the response of the pulmonary vasculature to hypoxia.
Topics: Amidohydrolases; Animals; Arginine; Blood Vessels; Cyclic GMP; Gene Expression; Hemodynamics; Hypertension, Pulmonary; Hypoxia; Lung; Mice; Nitric Oxide; Nitroarginine; Organ Culture Techniques; Oxadiazoles; Signal Transduction; Vasoconstriction | 2013 |
L-arginine-NO-cGMP signalling pathway in pancreatitis.
Topics: Aged; Arginine; Biomarkers; Case-Control Studies; Cyclic GMP; Female; Fluorescent Antibody Technique; Guanosine; Humans; Immunoenzyme Techniques; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Pancreas; Pancreatitis; Signal Transduction; Tyrosine | 2013 |
Effects of non-surgical periodontal treatment on the L-arginine-nitric oxide pathway and oxidative status in platelets.
Topics: Adult; Arginine; Blood Platelets; C-Reactive Protein; Cardiovascular Diseases; Cyclic GMP; Humans; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Periodontitis; Platelet Activation; Platelet Aggregation; Signal Transduction | 2013 |
Cyclic di-GMP inhibits Vibrio cholerae motility by repressing induction of transcription and inducing extracellular polysaccharide production.
Topics: Arginine; Bacterial Proteins; Binding Sites; Cyclic GMP; Flagella; Gene Expression Regulation, Bacterial; Histidine; Models, Molecular; Movement; Mutation; Operon; Polysaccharides, Bacterial; Protein Conformation; Protein Structure, Tertiary; Transcription, Genetic; Vibrio cholerae | 2013 |
Structural basis for cyclic-nucleotide selectivity and cGMP-selective activation of PKG I.
Topics: Amino Acid Sequence; Arginine; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Cyclic AMP; Cyclic GMP; Cyclic GMP-Dependent Protein Kinase Type I; Escherichia coli; Gene Expression; HEK293 Cells; Humans; Kinetics; Leucine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Recombinant Proteins; Sequence Alignment; Thermodynamics | 2014 |
L-arginine improves endothelial function, independently of arginine uptake, in aortas from chronic renal failure female rats.
Topics: Animals; Aorta; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Endothelial Cells; Endothelium, Vascular; Female; Kidney; Kidney Failure, Chronic; Nitric Oxide Synthase Type III; Rats | 2014 |
Ang-(1-7) activates the NO/cGMP and ATP-sensitive K+ channels pathway to induce peripheral antinociception in rats.
Topics: Adenosine Triphosphate; Analgesics; Angiotensin I; Animals; Arginine; Cyclic GMP; Dinoprostone; Dose-Response Relationship, Drug; Hyperalgesia; KATP Channels; Male; Nitric Oxide; Pain; Pain Measurement; Peptide Fragments; Rats; Rats, Wistar | 2014 |
Antidepressant-like effect of nitric oxide synthase inhibitors and sildenafil against lipopolysaccharide-induced depressive-like behavior in mice.
Topics: Animals; Antidepressive Agents; Arginine; Behavior, Animal; Brain; Brain-Derived Neurotrophic Factor; Cyclic GMP; Depressive Disorder; Disease Models, Animal; Enzyme Inhibitors; Guanidines; Imipramine; Interleukin-1beta; Lipopolysaccharides; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Piperazines; Purines; Signal Transduction; Sildenafil Citrate; Sulfones | 2014 |
Hesperidin exerts antidepressant-like effects in acute and chronic treatments in mice: possible role of l-arginine-NO-cGMP pathway and BDNF levels.
Topics: Animals; Antidepressive Agents; Arginine; Brain-Derived Neurotrophic Factor; Cyclic GMP; Hesperidin; Hippocampus; Male; Mice; Motor Activity; Nitric Oxide; Signal Transduction | 2014 |
Heme oxygenase suppresses markers of heart failure and ameliorates cardiomyopathy in L-NAME-induced hypertension.
Topics: Adiponectin; Aldosterone; Animals; Antioxidants; Arginine; Atrial Natriuretic Factor; Biomarkers; Blood Pressure; Cardiomyopathies; Cardiotonic Agents; Chemokine CCL2; Chemokine CCL3; Cyclic GMP; Dinoprost; Endothelin-1; Enzyme Induction; Extracellular Matrix Proteins; Heart Failure; Heme; Heme Oxygenase (Decyclizing); Hypertension; Interleukin-1beta; Interleukin-6; Male; NG-Nitroarginine Methyl Ester; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha; Tyrosine | 2014 |
miR-21/DDAH1 pathway regulates pulmonary vascular responses to hypoxia.
Topics: Amidohydrolases; Animals; Arginine; Cells, Cultured; Cyclic GMP; Endothelial Cells; Familial Primary Pulmonary Hypertension; Humans; Hypertension, Pulmonary; Hypoxia; Lung; Male; Mice; Mice, Transgenic; MicroRNAs; Myocytes, Smooth Muscle | 2014 |
The Nitric oxide/CGMP/KATP pathway mediates systemic and central antinociception induced by resistance exercise in rats.
Topics: Animals; Arginine; Cyclic GMP; Enzyme Inhibitors; Glyburide; Guanidines; Guanylate Cyclase; KATP Channels; Male; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Nociception; Ornithine; Oxadiazoles; Pain Measurement; Physical Conditioning, Animal; Quinoxalines; Rats; Signal Transduction | 2015 |
Involvement of L-arginine/NO/cGMP/K(ATP) channel pathway in the peripheral antinociceptive actions of ellagic acid in the rat formalin test.
Topics: Analgesics; Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Drug Interactions; Ellagic Acid; Glyburide; KATP Channels; Male; Methylene Blue; Morphine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Pain Measurement; Rats; Signal Transduction | 2014 |
Colitis generates remote antinociception in rats: the role of the L-arginine/NO/cGMP/PKG/KATP pathway and involvement of cannabinoid and opioid systems.
Topics: Analgesics, Opioid; Animals; Arginine; Cannabinoids; Carrageenan; Colitis; Colon; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dinoprostone; KATP Channels; Male; Neurons; Nitric Oxide; Nociception; Rats; Rats, Wistar; Trinitrobenzenesulfonic Acid | 2014 |
Oral supplementation with a combination of L-citrulline and L-arginine rapidly increases plasma L-arginine concentration and enhances NO bioavailability.
Topics: Administration, Oral; Animals; Arginine; Atherosclerosis; Biological Availability; Citrulline; Cyclic GMP; Dietary Supplements; Drug Synergism; Humans; Male; Nitric Oxide; Rabbits; Rats; Rats, Sprague-Dawley; Signal Transduction | 2014 |
Nitric oxide modulates a swimmeret beating rhythm in the crayfish.
Topics: Animals; Arginine; Astacoidea; Carbachol; Cyclic GMP; Electrophysiology; Enzyme Inhibitors; Female; Guanylate Cyclase; In Vitro Techniques; Motor Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase | 2014 |
Nitric oxide involvement in the antidepressant-like effect of ketamine in the Flinders sensitive line rat model of depression.
Topics: Anesthetics, Dissociative; Animals; Antidepressive Agents; Arginine; Behavior, Animal; Cyclic GMP; Depression; Disease Models, Animal; Frontal Lobe; Hippocampus; Ketamine; Male; Motor Activity; Nitric Oxide; Random Allocation; Rats; Receptors, N-Methyl-D-Aspartate | 2015 |
Effects of hyperbaric oxygen on nitric oxide generation in humans.
Topics: Adult; Arginine; Breath Tests; Citrulline; Cyclic GMP; Humans; Hyperbaric Oxygenation; Nitrates; Nitric Oxide; Nitrites; Oxygen; Saliva; Tongue; Young Adult | 2015 |
Tingenone, a pentacyclic triterpene, induces peripheral antinociception due to NO/cGMP and ATP-sensitive K(+) channels pathway activation in mice.
Topics: Analgesics; Animals; Arginine; Cyclic GMP; Dinoprostone; Hyperalgesia; KATP Channels; Male; Maytenus; Mice; Nitric Oxide; Plant Roots; Signal Transduction; Triterpenes | 2015 |
Effect of DDAH/ADMA/NOS regulation pathway on cavernae corporum cavernosorum rat penis of different age.
Topics: Amidohydrolases; Animals; Arginine; Cyclic GMP; Male; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Papaverine; Penis; Rats; Rats, Sprague-Dawley | 2016 |
L-citrulline for protection of endothelial function from ADMA-induced injury in porcine coronary artery.
Topics: Animals; Arginine; Cardiovascular Agents; Citrulline; Coronary Vessels; Cyclic GMP; Drug Evaluation, Preclinical; Endothelium, Vascular; Nitric Oxide Synthase Type III; Phosphorylation; Protein Processing, Post-Translational; Superoxides; Sus scrofa; Vascular System Injuries | 2015 |
Small molecules with big effects: Cyclic di-GMP-mediated stimulation of cellulose production by the amino acid ʟ-arginine.
Topics: Arginine; Cyclic GMP; Periplasm; Salmonella typhimurium; Signal Transduction | 2015 |
A direct screen for c-di-GMP modulators reveals a Salmonella Typhimurium periplasmic ʟ-arginine-sensing pathway.
Topics: Amino Acids; Arginine; Bacterial Proteins; Carrier Proteins; Cellulose; Cyclic GMP; Escherichia coli Proteins; Flow Cytometry; Fluorescence Resonance Energy Transfer; Mutation; Periplasm; Phosphorus-Oxygen Lyases; Salmonella typhimurium; Second Messenger Systems; Signal Transduction | 2015 |
Arginine Thiazolidine Carboxylate Stimulates Insulin Secretion through Production of Ca2+-Mobilizing Second Messengers NAADP and cADPR in Pancreatic Islets.
Topics: Animals; Arginine; Calcium; Calcium Signaling; Cyclic ADP-Ribose; Cyclic AMP; Cyclic GMP; Gene Expression; Glutathione; Hypoglycemic Agents; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mice; Mice, Inbred ICR; Mice, Knockout; NADP; Nitric Oxide; Nitric Oxide Synthase Type I; Prodrugs; Thiazolidines; Tissue Culture Techniques | 2015 |
Protective effect of nitric oxide in aristolochic acid-induced toxic acute kidney injury: an old friend with new assets.
Topics: Acute Kidney Injury; Animals; Arginine; Aristolochic Acids; Creatinine; Cyclic GMP; Kidney; Kidney Tubules, Proximal; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Oxidative Stress; Polyuria; Proteinuria; Sodium; Superoxide Dismutase | 2016 |
The involvement of NMDA receptor/NO/cGMP pathway in the antidepressant like effects of baclofen in mouse force swimming test.
Topics: Animals; Antidepressive Agents; Arginine; Baclofen; Cyclic GMP; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Indazoles; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phosphodiesterase 5 Inhibitors; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Sildenafil Citrate; Stress, Psychological; Swimming | 2016 |
Nitric oxide inhibits basolateral 10-pS Cl
Topics: Animals; Arginine; Chloride Channels; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Loop of Henle; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Donors; S-Nitroso-N-Acetylpenicillamine; Signal Transduction | 2016 |
N-methylnicotinamide protects against endothelial dysfunction and attenuates atherogenesis in apolipoprotein E-deficient mice.
Topics: Acetylcholine; Amidohydrolases; Animals; Aorta; Arginine; Atherosclerosis; Cholesterol, Dietary; Cyclic GMP; Diet, High-Fat; Endothelium, Vascular; Human Umbilical Vein Endothelial Cells; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Niacinamide; Nitric Oxide; Promoter Regions, Genetic; Vasodilation | 2016 |
Possible involvement of L-arginine-nitric oxide (NO)-cyclic guanosine monophosphate (cGMP) signaling pathway in the antidepressant-like effect of Wuling mycelia powder in rat.
Topics: Animals; Antidepressive Agents; Arginine; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Feeding Behavior; Food Preferences; Hippocampus; Indazoles; Male; Methylene Blue; Mycelium; Nitric Oxide; Powders; Rats, Sprague-Dawley; Signal Transduction; Sildenafil Citrate; Stress, Psychological; Sucrose | 2016 |
Involvement of NMDA receptors and L-arginine/nitric oxide/cyclic guanosine monophosphate pathway in the antidepressant-like effects of topiramate in mice forced swimming test.
Topics: Animals; Antidepressive Agents; Arginine; Behavior, Animal; Cyclic GMP; Depression; Enzyme Inhibitors; Fructose; Hindlimb Suspension; Male; Mice; Nitric Oxide; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Swimming; Topiramate | 2016 |
Contribution of NMDA, GABAA and GABAB receptors and l-arginine-NO-cGMP, MEK1/2 and CaMK-II pathways in the antidepressant-like effect of 7-fluoro-1,3-diphenylisoquinoline-1-amine in mice.
Topics: Animals; Antidepressive Agents; Arginine; Biological Transport; Cyclic GMP; Glutamic Acid; Locomotion; Male; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mice; N-Methylaspartate; Nitric Oxide; Quinolines; Receptors, GABA-A; Receptors, GABA-B; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2016 |
Platelet hyperaggregability in obesity: is there a role for nitric oxide impairment and oxidative stress?
Topics: Adult; Arginine; Blood Platelets; Cross-Sectional Studies; Cyclic GMP; Female; Humans; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Obesity; Oxidative Stress; Platelet Aggregation | 2016 |
Peritoneal dialysis impairs nitric oxide homeostasis and may predispose infants with low systolic blood pressure to cerebral ischemia.
Topics: Arginine; Blood Pressure; Brain; Brain Ischemia; Cerebrovascular Circulation; Cyclic GMP; Female; Homeostasis; Humans; Hypotension; Infant; Infant, Newborn; Male; Nitrates; Nitric Oxide; Nitrites; Peritoneal Dialysis | 2016 |
Antidepressant effect of pramipexole in mice forced swimming test: A cross talk between dopamine receptor and NMDA/nitric oxide/cGMP pathway.
Topics: Animals; Antidepressive Agents; Arginine; Benzothiazoles; Cyclic GMP; Dizocilpine Maleate; Haloperidol; Immobilization; Injections, Intraperitoneal; Male; Methylene Blue; Mice; Motor Activity; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pramipexole; Receptors, Dopamine; Signal Transduction; Sildenafil Citrate; Swimming | 2016 |
Phenylephrine Decreases Vascular Tension in Goat Arteries in Specific Circumstances.
Topics: Adrenergic alpha-1 Receptor Agonists; Animals; Arginine; Arteries; Cyclic GMP; Goats; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type III; Nitroprusside; Phenylephrine; Sildenafil Citrate; Vasoconstriction | 2016 |
Crystal structure of the YajQ-family protein XC_3703 from Xanthomonas campestris pv. campestris.
Topics: Amino Acid Sequence; Arginine; Bacterial Proteins; Binding Sites; Cloning, Molecular; Crystallography, X-Ray; Cyclic GMP; Escherichia coli; Gene Expression; Models, Molecular; Phenylalanine; Plasmids; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Recombinant Proteins; RNA-Binding Proteins; Second Messenger Systems; Sequence Alignment; Structural Homology, Protein; Xanthomonas campestris | 2016 |
Intracerebral Administration of S-Adenosylhomocysteine or S-Adenosylmethionine Attenuates the Increases in the Cortical Extracellular Levels of Dimethylarginines Without Affecting cGMP Level in Rats with Acute Liver Failure.
Topics: Animals; Arginine; Cyclic GMP; Disease Models, Animal; Extracellular Space; Hepatic Encephalopathy; Liver Failure, Acute; Male; Prefrontal Cortex; Protein-Arginine N-Methyltransferases; Rats, Sprague-Dawley; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Signal Transduction | 2017 |
The Importance of L-Arginine:NO:cGMP Pathway in Tolerance to Flunitrazepam in Mice.
Topics: Animals; Arginine; Cyclic GMP; Drug Interactions; Drug Tolerance; Flunitrazepam; Indazoles; Male; Mice; Motor Skills; NG-Nitroarginine Methyl Ester; Nitric Oxide; Signal Transduction; Sildenafil Citrate | 2017 |
Involvement of DDAH/ADMA/NOS/cGMP and COX-2/PTGIS/cAMP Pathways in Human Tissue Kallikrein 1 Protecting Erectile Function in Aged Rats.
Topics: Aging; Amidohydrolases; Animals; Arginine; Cyclic AMP; Cyclic GMP; Cyclooxygenase 2; Cytochrome P-450 Enzyme System; Erectile Dysfunction; Humans; Intramolecular Oxidoreductases; Male; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Penile Erection; Penis; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Recombinant Proteins; RNA, Messenger; Signal Transduction; Tissue Kallikreins | 2017 |
Endothelial Cells Inhibit the Angiotensin II Induced Phenotypic Modulation of Rat Vascular Adventitial Fibroblasts.
Topics: Actins; Adventitia; Angiotensin II; Animals; Aorta, Thoracic; Arginine; Cells, Cultured; Coculture Techniques; Collagen Type I; Cyclic GMP; Endothelial Cells; Fibroblasts; Homocysteine; NG-Nitroarginine Methyl Ester; Rats; Rats, Sprague-Dawley; Signal Transduction | 2017 |
Knockdown of a putative argininosuccinate lyase gene reduces arginine content and impairs nymphal development in Nilaparvata lugens.
Topics: Abdomen; Animals; Arginine; Argininosuccinate Lyase; Ascomycota; Cloning, Molecular; Cyclic GMP; Gene Knockdown Techniques; Hemiptera; Insect Proteins; Nitric Oxide; Nymph; Phylogeny; RNA Interference | 2017 |
Mutations of PKA cyclic nucleotide-binding domains reveal novel aspects of cyclic nucleotide selectivity.
Topics: Amino Acid Substitution; Arginine; Binding Sites; Computational Biology; Crystallography, X-Ray; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase RIalpha Subunit; Cyclic GMP; Expert Systems; Humans; Kinetics; Ligands; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Peptide Fragments; Protein Interaction Domains and Motifs; Recombinant Fusion Proteins; Recombinant Proteins; Threonine | 2017 |
Endogenous nitric oxide inhibits spinal NMDA receptor activity and pain hypersensitivity induced by nerve injury.
Topics: Analgesics, Non-Narcotic; Animals; Arginine; Central Nervous System Agents; Cyclic GMP; Disease Models, Animal; Ethylmaleimide; Excitatory Amino Acid Antagonists; Hot Temperature; Hyperalgesia; Male; Neuralgia; Nitric Oxide; Nitric Oxide Synthase Type I; Posterior Horn Cells; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; S-Nitroso-N-Acetylpenicillamine; Soluble Guanylyl Cyclase; Spinal Nerves; Tissue Culture Techniques; Touch | 2017 |
REM sleep deprivation induces endothelial dysfunction and hypertension in middle-aged rats: Roles of the eNOS/NO/cGMP pathway and supplementation with L-arginine.
Topics: Animals; Arginine; Blood Pressure; Cyclic GMP; Hypertension; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Signal Transduction; Sleep Deprivation | 2017 |
Venlafaxine Attenuates the Development of Morphine Tolerance and Dependence: Role of L-Arginine/Nitric Oxide/cGMP Pathway.
Topics: Analgesics, Opioid; Animals; Arginine; Behavior, Animal; Brain; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Tolerance; Male; Mice; Morphine; Morphine Dependence; Nitric Oxide; Nociceptive Pain; Signal Transduction; Time Factors; Venlafaxine Hydrochloride | 2018 |
Role of l-arginine/SNAP/NO/cGMP/K
Topics: Analgesics; Animals; Arginine; Cyclic GMP; Cyclohexane Monoterpenes; Cyclohexenes; Dose-Response Relationship, Drug; KATP Channels; Male; Mice; Monoterpenes; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pain; Pain Measurement; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; Treatment Outcome | 2018 |
A c-di-GMP-Modulating Protein Regulates Swimming Motility of
Topics: Amino Acid Sequence; Amino Acids; Arginine; Bacterial Proteins; Biofilms; Burkholderia cenocepacia; Burkholderia Infections; Cloning, Molecular; Cyclic GMP; Cystic Fibrosis; Escherichia coli Proteins; Flagellin; Gene Expression Regulation, Bacterial; Glutamic Acid; Locomotion; Lung; Mutagenesis, Insertional; Peptide Hydrolases; Phosphoric Diester Hydrolases; Phosphorus-Oxygen Lyases; Sequence Alignment; Sputum | 2018 |
Nitric oxide modulates ATP-evoked currents in mouse Leydig cells.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Arginine; Cells, Cultured; Cyclic GMP; Leydig Cells; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Patch-Clamp Techniques; Receptors, Purinergic; Thionucleotides | 2018 |
A novel bacterial l-arginine sensor controlling c-di-GMP levels in Pseudomonas aeruginosa.
Topics: Amino Acid Sequence; Arginine; Bacterial Proteins; Cyclic GMP; Escherichia coli Proteins; Humans; Hydrolysis; Models, Molecular; Phosphoric Diester Hydrolases; Phosphorus-Oxygen Lyases; Protein Binding; Protein Domains; Pseudomonas aeruginosa; Pseudomonas Infections; Sequence Alignment | 2018 |
Effects of isopulegol in acute nociception in mice: Possible involvement of muscarinic receptors, opioid system and l-arginine/NO/cGMP pathway.
Topics: Acute Disease; Administration, Oral; Analgesics; Animals; Arginine; Behavior, Animal; Capsaicin; Cyclic GMP; Cyclohexane Monoterpenes; Female; Formaldehyde; Glutamic Acid; Male; Mice; Nitric Oxide; Pain; Receptors, Muscarinic; Receptors, Opioid; Signal Transduction; Terpenes | 2018 |
The role of nitric oxide-cGMP pathway in selegiline antidepressant-like effect in the mice forced swim test.
Topics: Animals; Antidepressive Agents; Arginine; Cyclic GMP; Drug Synergism; Fluoxetine; Guanidines; Hippocampus; Immobility Response, Tonic; Indazoles; Male; Methylene Blue; Mice; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Prefrontal Cortex; Selegiline; Signal Transduction; Sildenafil Citrate; Swimming | 2018 |
Attenuation of glutamatergic and nitrergic system contributes to the antidepressant-like effect induced by capsazepine in the forced swimming test.
Topics: 2-Amino-5-phosphonovalerate; Animals; Antidepressive Agents; Apomorphine; Arginine; Capsaicin; Cyclic GMP; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Enzyme Inhibitors; Exploratory Behavior; Glutamic Acid; Male; Microinjections; Nitric Oxide; Nitroprusside; Rats; Receptors, N-Methyl-D-Aspartate; Statistics, Nonparametric; Swimming | 2019 |
Probucol improves erectile function via Activation of Nrf2 and coordinates the HO-1 / DDAH / PPAR-γ/ eNOS pathways in streptozotocin-induced diabetic rats.
Topics: Amidohydrolases; Animals; Arginine; Blood Glucose; Body Weight; Cyclic GMP; Diabetes Mellitus, Experimental; Erectile Dysfunction; Heme Oxygenase-1; Male; Malondialdehyde; NF-E2-Related Factor 2; Nitric Oxide Synthase Type III; PPAR gamma; Probucol; Rats, Sprague-Dawley; Signal Transduction; Streptozocin; Superoxide Dismutase | 2018 |
Pharmacological evidence for the relationship between the NMDA receptor and nitric oxide pathway and the antidepressant-like effects of glucagon-like peptide-2 in the mouse forced-swim test.
Topics: Animals; Antidepressive Agents; Arginine; Cyclic GMP; Depression; Dizocilpine Maleate; Glucagon-Like Peptide 2; Indazoles; Male; Methylene Blue; Mice; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phosphodiesterase 5 Inhibitors; Receptors, N-Methyl-D-Aspartate; Serine; Signal Transduction; Sildenafil Citrate; Swimming | 2019 |
Exogenous l-ARGININE does not stimulate production OF NO or cGMP within the rat corporal smooth muscle cells in culture.
Topics: Animals; Arginine; Cells, Cultured; Citrulline; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Male; Muscle, Smooth; Myocytes, Smooth Muscle; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Penis; Phosphodiesterase 5 Inhibitors; Rats, Sprague-Dawley | 2019 |
NMDA receptors and L-arginine/nitric oxide/cyclic guanosine monophosphate pathway contribute to the antidepressant-like effect of Yueju pill in mice.
Topics: Animals; Antidepressive Agents; Anxiety; Arginine; Cyclic GMP; Depression; Drugs, Chinese Herbal; Hindlimb Suspension; Ketamine; Male; Mice; Mice, Inbred BALB C; Nitric Oxide; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2019 |
Nitric oxide impacts bovine sperm capacitation in a cGMP-dependent and cGMP-independent manner.
Topics: Animals; Arginine; Cattle; Cryopreservation; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cyclic N-Oxides; Heparin; Imidazoles; Male; Nitric Oxide; Sperm Capacitation; Sperm Motility; Spermatozoa; Thionucleotides | 2019 |
Montelukast, a cysteinyl leukotriene receptor antagonist, exerts local antinociception in animal model of pain through the L-arginine/nitric oxide/cyclic GMP/K
Topics: Acetates; Analgesia; Analgesics; Animals; Arginine; Behavior, Animal; Cyclic GMP; Cyclopropanes; Disease Models, Animal; KATP Channels; Leukotriene Antagonists; Male; Nitric Oxide; Nociceptive Pain; PPAR gamma; Quinolines; Rats, Wistar; Signal Transduction; Sulfides | 2021 |
Possible mechanisms mediating the protective effect of cilostazol in L-arginine induced acute pancreatitis in rats: role of cGMP, cAMP, and HO-1.
Topics: Animals; Arginine; Cilostazol; Cyclic AMP; Cyclic GMP; Heme Oxygenase (Decyclizing); Male; Oxidative Stress; Pancreatitis; Phosphodiesterase 3 Inhibitors; Rats; Rats, Wistar | 2020 |
Antinociceptive effect of Lonchocarpus araripensis lectin: activation of L-arginine/NO/cGMP/K
Topics: Adenosine Triphosphate; Analgesics; Animals; Arginine; Carrageenan; Cyclic GMP; Fabaceae; Ganglia, Spinal; Gene Expression; KATP Channels; Lectins; Male; Mice; Nitric Oxide; Nitric Oxide Synthase Type I; Signal Transduction | 2020 |
Arginine as an environmental and metabolic cue for cyclic diguanylate signalling and biofilm formation in Pseudomonas putida.
Topics: Arginine; Bacterial Proteins; Biofilms; Cyclic GMP; Gene Expression Regulation, Bacterial; Pseudomonas Infections; Pseudomonas putida | 2020 |
The antinociceptive mechanisms of melatonin: role of L-arginine/nitric oxide/cyclic GMP/KATP channel signaling pathway.
Topics: Analgesics; Animals; Animals, Outbred Strains; Arginine; Cyclic GMP; KATP Channels; Male; Melatonin; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pain; Signal Transduction | 2020 |
Antidepressant-like effect of ethanol in mice forced swimming test is mediated via inhibition of NMDA/nitric oxide/cGMP signaling pathway.
Topics: Animals; Antidepressive Agents; Arginine; Cyclic GMP; Depression; Ethanol; Mice; N-Methylaspartate; Nitric Oxide; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Swimming | 2021 |
Bupleurum falcatum L. alleviates nociceptive and neuropathic pain: Potential mechanisms of action.
Topics: Animals; Arginine; Bupleurum; Cyclic GMP; Formaldehyde; Hyperalgesia; Iran; Male; Medicine, Traditional; Mice; Nitric Oxide; Oils, Volatile; Pain; Phytotherapy; Plant Oils; Plant Roots; Potassium Channels; Spinal Cord Injuries | 2021 |
Nitric Oxide-cGMP Pathway Modulation in an Experimental Model of Hypoxic Pulmonary Hypertension.
Topics: Animals; Arginine; Cyclic GMP; Hypertension, Pulmonary; Hypoxia; Male; Myocardium; Nitric Oxide; Rats; Rats, Sprague-Dawley; Sildenafil Citrate; Vasodilator Agents | 2021 |
The anti-nociceptive activity of naringenin passes through L-arginine/NO/cGMP/KATP channel pathway and opioid receptors.
Topics: Analgesics; Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Drug Synergism; Estrogen Antagonists; Flavanones; Flavonoids; Infusions, Parenteral; KATP Channels; Male; Mice; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Receptors, Opioid; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; Sildenafil Citrate | 2021 |
Astaxanthin engages the l-arginine/NO/cGMP/KATP channel signaling pathway toward antinociceptive effects.
Topics: Analgesics; Animals; Arginine; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Glyburide; KATP Channels; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pain; Signal Transduction; Sildenafil Citrate; Xanthophylls | 2021 |
Putrescine and Its Metabolic Precursor Arginine Promote Biofilm and c-di-GMP Synthesis in Pseudomonas aeruginosa.
Topics: Arginine; Biofilms; Cyclic GMP; Gene Expression Regulation, Bacterial; Pseudomonas aeruginosa; Putrescine; Up-Regulation | 2022 |
Possible involvement of NO-sGC-cGMP signaling in the antidepressant like effect of pyridoxine in mice.
Topics: Animals; Antidepressive Agents; Arginine; Cyclic GMP; Depression; Mice; Nitric Oxide; Pyridoxine; Soluble Guanylyl Cyclase; Swimming | 2022 |
Antidepressant Like Effect of Ascorbic Acid in Mice: Possible Involvement of NO-sGC-cGMP Signaling.
Topics: Animals; Antidepressive Agents; Arginine; Ascorbic Acid; Cyclic GMP; Depression; Male; Mice; Nitric Oxide; Signal Transduction; Swimming | 2022 |
Role of the Transcriptional Regulator ArgR in the Connection between Arginine Metabolism and c-di-GMP Signaling in Pseudomonas putida.
Topics: Arginine; Bacterial Proteins; Biofilms; Cyclic GMP; Gene Expression Regulation, Bacterial; Pseudomonas putida | 2022 |
L-Arginine enhanced perylenequinone production in the endophytic fungus Shiraia sp. Slf14(w) via NO signaling pathway.
Topics: Acetyl Coenzyme A; Arginine; Ascomycota; Cyclic GMP; Nitric Oxide; Nitroprusside; Perylene; Quinones; Signal Transduction | 2022 |
Cyclic di-GMP triggers the hypoxic adaptation of Mycobacterium bovis through a metabolic switching regulator ArgR.
Topics: Arginine; Bacterial Proteins; Cyclic GMP; Gene Expression Regulation, Bacterial; Humans; Hypoxia; Mycobacterium bovis; Mycobacterium tuberculosis; Nitrites | 2022 |
Mechanistic pathways of fibromyalgia induced by intermittent cold stress in mice is sex-dependently.
Topics: Adenosine Triphosphatases; Animals; Arginine; Cold-Shock Response; Cyclic GMP; Dizocilpine Maleate; Female; Fibromyalgia; Male; Methylene Blue; Mice; N-Methylaspartate; Nitric Oxide; Quality of Life; Receptors, N-Methyl-D-Aspartate | 2022 |
Development of a red fluorescent protein-based cGMP indicator applicable for live-cell imaging.
Topics: Arginine; Cyclic GMP; Luminescent Proteins; Red Fluorescent Protein; Second Messenger Systems | 2022 |
The role of the L-arginine-NO-cGMP-dependent pathway in the development of sensitization to mephedrone effects on the locomotor activity in mice.
Topics: Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Locomotion; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide | 2023 |
L-Arginine reverses maternal and pre-pubertal codeine exposure-induced sexual dysfunction via upregulation of androgen receptor gene and NO/cGMP signaling.
Topics: Animals; Arginine; Codeine; Cyclic GMP; Dopamine; Female; Male; Pregnancy; Rats; Receptors, Androgen; RNA, Messenger; Testosterone; Up-Regulation | 2022 |
Magnesium sulphate activates the L-arginine/NO/cGMP pathway to induce peripheral antinociception in mice
Topics: Analgesics; Animals; Arginine; Cyclic GMP; Dinoprostone; Hyperalgesia; Magnesium Sulfate; Male; Mice; Nitric Oxide; Nitroarginine; Phosphodiesterase Inhibitors; Soluble Guanylyl Cyclase | 2022 |
The role of l -arginine/NO/cGMP/K ATP channel pathway in the local antinociceptive effect of berberine in the rat formalin test.
Topics: Adenosine Triphosphate; Analgesics; Animals; Arginine; Berberine; Cyclic GMP; Glyburide; KATP Channels; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pain Measurement; Rats; Rats, Wistar | 2023 |
The L-arginine-NO-cGMP pathway mediates the locomotor activity alterations during the expression of sensitization to mephedrone in mice.
Topics: Animals; Arginine; Cyclic GMP; Locomotion; Male; Methylene Blue; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide | 2023 |
The phosphodiesterase RmcA contributes to the adaptation of Pseudomonas putida to l-arginine.
Topics: Arginine; Bacterial Proteins; Biofilms; Cyclic GMP; Gene Expression Regulation, Bacterial; Humans; Phosphoric Diester Hydrolases; Pseudomonas aeruginosa; Pseudomonas putida | 2023 |