arginine has been researched along with 2'-deoxyuridylic acid in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cisneros, RJ; Deng, WL; Dunlap, RB; Johnson, LF; Zhang, HC | 1 |
| Fauman, EB; Finer-Moore, JS; Morse, RJ; Santi, DV; Stroud, RM | 1 |
| Changchien, L; Maley, F; Montfort, WR; Strop, P | 1 |
| Finer-Moore, J; Kawase, S; Morse, RJ; Santi, DV; Stroud, RM | 1 |
| Lee, TT; Liu, Y; Santi, DV; Stroud, RM; Variath, P | 1 |
| Cieśla, J; Gołos, B; Jagielska, E; Płucienniczak, A; Rode, W; Wałajtys-Rode, E | 1 |
| Changchien, L; Maley, F; Montfort, WR; Sotelo-Mundo, RR | 1 |
7 other study(ies) available for arginine and 2'-deoxyuridylic acid
| Article | Year |
|---|---|
Site-directed mutagenesis of mouse thymidylate synthase: alteration of Arg44 to Val44 in a conserved loop guarding the active site has striking effects on catalysis and nucleotide binding.
Topics: Amino Acid Sequence; Animals; Arginine; Base Sequence; Binding Sites; Catalysis; Deoxyuracil Nucleotides; Fluorodeoxyuridylate; Hydrogen Bonding; Kinetics; Mice; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Plasmids; Protein Conformation; Thymidylate Synthase; Valine | 1990 |
Contribution of a salt bridge to binding affinity and dUMP orientation to catalytic rate: mutation of a substrate-binding arginine in thymidylate synthase.
Topics: Arginine; Binding Sites; Catalysis; Crystallography, X-Ray; Deoxyuracil Nucleotides; Escherichia coli; Glutamic Acid; Hydrogen Bonding; Kinetics; Lacticaseibacillus casei; Models, Molecular; Molecular Structure; Mutagenesis; Phosphates; Protein Binding; Protein Conformation; Protein Engineering; Recombinant Proteins; Thymidylate Synthase | 1996 |
Crystal structures of a marginally active thymidylate synthase mutant, Arg 126-->Glu.
Topics: Antineoplastic Agents; Arginine; Binding Sites; Catalysis; Crystallization; Crystallography, X-Ray; Deoxyuracil Nucleotides; Dimerization; Folic Acid; Folic Acid Antagonists; Glutamic Acid; Hydrogen Bonding; Kinetics; Models, Molecular; Molecular Structure; Mutation; Phosphates; Quinazolines; Thymidylate Synthase | 1997 |
Energetic contributions of four arginines to phosphate-binding in thymidylate synthase are more than additive and depend on optimization of "effective charge balance".
Topics: Arginine; Binding Sites; Crystallography, X-Ray; Deoxyuracil Nucleotides; Hydrogen Bonding; Kinetics; Lacticaseibacillus casei; Mutagenesis, Site-Directed; Phosphates; Static Electricity; Structure-Activity Relationship; Thermodynamics; Threonine; Thymidylate Synthase | 2000 |
Effects of subunit occupancy on partitioning of an intermediate in thymidylate synthase mutants.
Topics: Alanine; Arginine; Catalysis; Deoxyuracil Nucleotides; Escherichia coli; Glycine; Kinetics; Lacticaseibacillus casei; Models, Chemical; Mutagenesis, Site-Directed; Peptide Fragments; Tetrahydrofolates; Thymidine Monophosphate; Thymidylate Synthase; Valine | 2000 |
The effect of Arg209 to Lys mutation in mouse thymidylate synthase.
Topics: Amino Acid Substitution; Animals; Arginine; Catalysis; Deoxyuracil Nucleotides; Enzyme Induction; Escherichia coli; Kinetics; Lacticaseibacillus casei; Leukemia L1210; Lysine; Mice; Recombinant Proteins; Solubility; Thymidylate Synthase; Tumor Cells, Cultured | 2002 |
Crystal structures of thymidylate synthase mutant R166Q: structural basis for the nearly complete loss of catalytic activity.
Topics: Amino Acid Substitution; Arginine; Binding Sites; Catalysis; Crystallization; Crystallography, X-Ray; Deoxyuracil Nucleotides; Dimerization; Escherichia coli; Folic Acid; Folic Acid Antagonists; Hydrogen Bonding; Kinetics; Ligands; Models, Molecular; Molecular Structure; Protein Binding; Protein Conformation; Recombinant Proteins; Thymidine Monophosphate; Thymidylate Synthase | 2006 |