arginine has been researched along with 1-methyl-3-isobutylxanthine in 72 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 10 (13.89) | 18.7374 |
1990's | 50 (69.44) | 18.2507 |
2000's | 11 (15.28) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 1 (1.39) | 2.80 |
Authors | Studies |
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Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
Eisenberg, HM; Hulsebosch, CE; Lu, Y; Morgan, B; Perez-Polo, JR; Pizzo, DP; Werrbach-Perez, K; Westlund, KN | 1 |
Altiok, N; Fredholm, BB | 1 |
Catravas, JD; Marczin, N; Ryan, US | 1 |
Gillespie, JS; Sheng, H | 1 |
Crowther, NJ; Gotfredsen, CF; Green, IC; Moody, AJ | 1 |
Ahrén, B; Efendic, S; Karlsson, S; Ostenson, CG; Sandberg, E | 1 |
Amiranoff, B; Laburthe, M; Lorinet, AM | 1 |
Junquero, DC; Schini, VB; Scott-Burden, T; Vanhoutte, PM | 1 |
Bergamini, E; Bombara, M; Fierabracci, V; Masiello, P; Novelli, M | 1 |
Dage, RC; French, JF; Lambert, LE | 1 |
Braquet, P; Chabrier, PE; Demerlé-Pallardy, C; Lonchampt, MO | 1 |
D'Alessio, DA; Ensinck, JW; Fujimoto, WY; Kahn, SE; Porte, D | 1 |
Anggard, E; Mollace, V; Salvemini, D; Vane, J | 1 |
Bonner-Weir, S; Leahy, JL; Weir, GC | 3 |
Hirata, Y; Machiyama, E; Ohgawara, H; Sakurai, Y; Tasaka, Y | 1 |
Gross, R; Karmann, H; Laurent, F; Mialhe, P; Strosser, MT | 1 |
Ariav, Y; Cerasi, E; Corcos, AP; Kaiser, N; Tur-Sinai, A | 1 |
Cerasi, E; Eylon, L; Nesher, R; Segal, N | 1 |
Grill, V | 1 |
Barras, E; Fletcher, DJ; Grogan, WM; Weir, GC | 1 |
Gold, G; Grodsky, GM; Nowlain, RM; Pou, J | 1 |
Giles, WR; Han, X; Shimoni, Y | 1 |
Fujitani, Y; Karaki, H; Okada, T; Ueda, H; Urade, Y | 1 |
Craven, PA; DeRubertis, FR; Studer, RK | 1 |
Ando, J; Kamiya, A; Korenaga, R; Sakuma, I; Toyo-oka, T; Tsuboi, H; Yang, W | 1 |
Anfossi, G; Cavalot, F; Massucco, P; Mattiello, L; Mularoni, E; Trovati, M | 2 |
Hirata, Y; Imai, T; Kanno, K; Marumo, F | 1 |
Marumo, F; Nonoguchi, H; Owada, A; Sakamoto, H; Terada, Y; Tomita, K | 1 |
De Kimpe, SJ; Nijkamp, FP; Radomski, MW; van Amsterdam, JG; Van Heuven-Nolsen, D | 1 |
Catravas, JD; Cheng, C; Marczin, N; Milici, A; Papapetropoulos, A; Snead, MD | 1 |
Gögelein, H; Popp, R; Schölkens, BA; Wiemer, G | 1 |
Hartell, NA | 1 |
Armstead, WM; Leffler, CW; Parfenova, H; Shibata, M; Zuckerman, SL | 1 |
McKenna, TM; Tao, S | 1 |
Glusa, E | 1 |
Chik, CL; Ho, AK; Murdoch, G; Ogiwara, T | 1 |
Akesson, B; Lundquist, I; Panagiotidis, G; Rydell, EL | 1 |
Ikeda, M; Ikeda, U; Kano, S; Ohkawa, F; Shimada, K | 1 |
Bousquet, J; Dugas, B; Paul-Eugène, N; Pène, J | 1 |
Bartoli, F; Billiar, TR; Di Silvio, M; Dorko, K; Freeswick, P; Geller, DA; Liu, ZZ; Nussler, AK | 1 |
Bergamini, E; Bombara, M; Masiello, P; Novelli, M | 1 |
Kolb, H; Kolb-Bachofen, V; Kröncke, KD; Rodriguez, ML | 1 |
Cunningham, JM; Delaney, CA; Green, IC; Karmiris, V; Southern, C | 1 |
Björklund, A; Grill, V | 1 |
Damais, C; Frelin, C; Vigne, P | 1 |
Blum, G; Caramelo, C; Casado, S; Gallego, MJ; López Farré, A; Montón, M; Riesco, A | 1 |
Ikeda, M; Kaji, K; Morita, I; Murota, S; Nagao, M; Sato, I | 1 |
Carreau, A; Nowicki, JP; Scatton, B; Vigé, X | 1 |
Bedwani, JR; Datta, S; German, K; Stephenson, TP; Williams, P | 1 |
Chou, TC; Ding, YA; Hong, HJ; Wu, CC; Yen, MH | 1 |
Graham, A; Owen, JS; Riddell, DR | 1 |
Dun, NJ; Dun, SL; Förstermann, U; Wu, SY | 1 |
Hori, M; Hoshida, S; Igarashi, J; Kosaka, H; Kuzuya, T; Nishida, M; Tada, M; Yamashita, N | 1 |
Cattell, V; Cook, HT; Tam, FW; Waddington, SN | 1 |
Bina, S; Hart, JL; Muldoon, SM; Sei, Y | 1 |
Cardenas, P; Chacin, J; Hernandez, IM; Lobo, P; Molero, M; Romero, R | 1 |
Bertuzzi, F; Di Carlo, V; Leone, BE; Nano, R; Piemonti, L; Pozza, G; Socci, C | 1 |
Beinborn, M; Morales, RE; Nagy, L; Szabo, S; Vattay, P | 1 |
Colucci, M; Levi, G; Patrizio, M | 1 |
Hashimoto, T; Nawata, H; Sako, Y; Tajiri, Y; Umeda, F; Yoshikawa, H | 1 |
Garthwaite, G; Garthwaite, J; Goodwin, DA; Griffiths, C | 1 |
de Lamirande, E; Gagnon, C; Thundathil, J | 1 |
Akesson, B; Lundquist, I; Panagiotidis, G; Westermark, P | 1 |
Caffrey, JL; Farias, M; Jackson, K; Johnson, M | 1 |
Dornonville de la Cour, C; Håkanson, R; Lundquist, I; Salehi, A | 1 |
Ahmed, Z; Batchelor, AM; Cuzner, ML; Garthwaite, G; Garthwaite, J; Goodwin, DA; Hewson, AK; Leeming, K | 1 |
Atreja, SK; Roy, SC | 1 |
Conrad, LJ; Daut, J; Koschinsky, K; Krüger, J; Netz, E; Preisig-Müller, R; Renigunta, V; Schlichthörl, G; Zou, X | 1 |
1 review(s) available for arginine and 1-methyl-3-isobutylxanthine
Article | Year |
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Experimental reduction of B-cell mass: implications for the pathogenesis of diabetes.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Animals, Newborn; Arginine; Blood Glucose; Cyclic AMP; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Drug Synergism; Glucagon; Glucose; Glucose Tolerance Test; Histocytochemistry; Humans; Immunologic Techniques; In Vitro Techniques; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Pancreatectomy; Rats; Rats, Inbred Strains | 1986 |
71 other study(ies) available for arginine and 1-methyl-3-isobutylxanthine
Article | Year |
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Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Effects of nerve growth factor and acetyl-L-carnitine arginyl amide on the human neuronal line HCN-1A.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcarnitine; Animals; Arginine; Brain Chemistry; Cell Differentiation; Cell Line; Colforsin; gamma-Aminobutyric Acid; Humans; Immunohistochemistry; Mice; Nerve Growth Factors; Neurofilament Proteins; Neurons | 1992 |
Bradykinin inhibition of cyclic AMP accumulation in D384 astrocytoma cells. Evidence against a role of cyclic GMP.
Topics: 1-Methyl-3-isobutylxanthine; Arginine; Astrocytoma; Bradykinin; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Humans; Hydroxylamine; Hydroxylamines; Kinetics; NG-Nitroarginine Methyl Ester; Nitroprusside; Pyrrolidinones; Rolipram; Tumor Cells, Cultured | 1992 |
Endothelial cGMP does not regulate basal release of endothelium-derived relaxing factor in culture.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Atrial Natriuretic Factor; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Vasodilator Agents | 1992 |
The effects of pyrogallol and hydroquinone on the response to NANC nerve stimulation in the rat anococcygeus and the bovine retractor penis muscles.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Autonomic Nervous System; Cattle; Electric Stimulation; Hydroquinones; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; omega-N-Methylarginine; Penis; Pyrogallol; Rats; Superoxides | 1990 |
Immunological and insulin secretory studies on isolated porcine islets of Langerhans.
Topics: 1-Methyl-3-isobutylxanthine; 3-Hydroxybutyric Acid; Animals; Antigens, Surface; Arginine; Caprylates; Glucose; Hydroxybutyrates; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Stimulation, Chemical; Swine | 1990 |
Effects of porcine diazepam-binding inhibitor on insulin and glucagon secretion in vitro from the rat endocrine pancreas.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Diazepam Binding Inhibitor; Glucagon; Glucose; Glyburide; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Neuropeptides; Rats; Rats, Inbred Strains; Somatostatin; Stimulation, Chemical; Swine | 1990 |
Galanin inhibits somatostatin release by the rat islet cell tumor in culture, Rin-m.
Topics: 1-Methyl-3-isobutylxanthine; Adenoma, Islet Cell; Animals; Aprotinin; Arginine; Depression, Chemical; Galanin; Pancreatic Neoplasms; Peptides; Pertussis Toxin; Somatostatin; Swine; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1990 |
Interleukin-1 beta induces the production of an L-arginine-derived relaxing factor from cultured smooth muscle cells from rat aorta.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Aorta, Thoracic; Arginine; Biological Assay; Cells, Cultured; Coronary Vessels; Cyclic GMP; Dogs; In Vitro Techniques; Indomethacin; Interleukin-1; Kinetics; Muscle, Smooth, Vascular; Rats; Rats, Inbred Strains; Stereoisomerism; Vasodilator Agents | 1991 |
Effects of different regimens of dietary restriction on the age-related decline in insulin secretory response of isolated rat pancreatic islets.
Topics: 1-Methyl-3-isobutylxanthine; Aging; Animals; Arginine; Diet, Reducing; Energy Intake; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Male; Potassium Chloride; Rats; Rats, Inbred Strains; Reference Values | 1991 |
Nitric oxide synthase inhibitors inhibit interleukin-1 beta-induced depression of vascular smooth muscle.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Oxidoreductases; Animals; Arginine; Cells, Cultured; Interleukin-1; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Norepinephrine; Rats; Rats, Inbred Strains; Vasoconstriction | 1991 |
Absence of implication of L-arginine/nitric oxide pathway on neuronal cell injury induced by L-glutamate or hypoxia.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Brain; Cell Hypoxia; Cells, Cultured; Cyclic GMP; Dizocilpine Maleate; Fetus; Glutamates; Glutamic Acid; Kainic Acid; Kinetics; N-Methylaspartate; Neuroglia; Neurons; Nitric Oxide; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Quisqualic Acid; Rats | 1991 |
Glucose stimulates and potentiates islet amyloid polypeptide secretion by the B-cell.
Topics: 1-Methyl-3-isobutylxanthine; Amyloid; Animals; Arginine; Cells, Cultured; Drug Synergism; Glucose; Insulin; Insulin Secretion; Islet Amyloid Polypeptide; Islets of Langerhans; Rats; Rats, Inbred Strains | 1991 |
Nitric oxide from vascular smooth muscle cells: regulation of platelet reactivity and smooth muscle cell guanylate cyclase.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Atrial Natriuretic Factor; Blood Platelets; Cattle; Cyclic GMP; Cycloheximide; Escherichia coli; Guanylate Cyclase; Humans; In Vitro Techniques; Lipopolysaccharides; Macrophages; Mice; Monocytes; Muscle, Smooth; Muscle, Smooth, Vascular; Nitric Oxide; Nitroglycerin; omega-N-Methylarginine; Superoxide Dismutase; Thrombin | 1991 |
Abnormal insulin secretion in a streptozocin model of diabetes. Effects of insulin treatment.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Glucagon; Insulin; Insulin Secretion; Islets of Langerhans; Male; Rats; Rats, Inbred Strains | 1985 |
A study of insulin and glucagon secretion from adult rat pancreatic monolayer islets.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Culture Media; Culture Techniques; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Microbial Collagenase; Rats; Rats, Inbred Strains | 1985 |
Glucagon and somatostatin secretion from the perfused splenic bulb of duck pancreas.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acids; Animals; Arginine; Ducks; Glucagon; Glucose; Insulin; Insulin Secretion; Male; Pancreas; Perfusion; Somatostatin | 1986 |
Monolayer culture of adult rat pancreatic islets on extracellular matrix: long term maintenance of differentiated B-cell function.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Cells, Cultured; Epinephrine; Extracellular Matrix; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Male; Rats; Somatostatin; Time Factors | 1988 |
Beta-cell memory to insulin secretagogues: characterization of the time-dependent inhibitory control system in the isolated rat pancreas.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Dose-Response Relationship, Drug; Epinephrine; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Rats; Time Factors; Tolbutamide | 1989 |
Nutrient-induced priming of insulin and glucagon secretion. Effects of alpha-ketoisocaproic acid.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Caproates; Glucagon; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Kinetics; Male; Rats; Rats, Inbred Strains | 1982 |
Hormone release by islet B cell-enriched and A and D cell-enriched populations prepared by flow cytometry.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Flow Cytometry; Glucagon; Glucose; Glyburide; Insulin; Islets of Langerhans; Male; Rats; Rats, Inbred Strains | 1983 |
Abnormal glucose regulation of insulin secretion in models of reduced B-cell mass.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Animals, Newborn; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Male; Pancreatectomy; Perfusion; Radioimmunoassay; Rats; Rats, Inbred Strains; Streptozocin | 1984 |
Effects of monensin on conversion of proinsulin to insulin and secretion of newly synthesized insulin in isolated rat islets.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Biological Transport; Furans; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Monensin; Proinsulin; Rats | 1984 |
A cellular mechanism for nitric oxide-mediated cholinergic control of mammalian heart rate.
Topics: 1-Methyl-3-isobutylxanthine; Aminoquinolines; Animals; Arginine; Carbachol; Cardiotonic Agents; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Enzyme Inhibitors; GTP-Binding Proteins; Guanylate Cyclase; Heart Rate; Isoproterenol; Methylene Blue; Molsidomine; Muscarinic Agonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Aggregation Inhibitors; Rabbits; Receptors, Cholinergic; Receptors, Muscarinic; Sinoatrial Node; Thionucleotides | 1995 |
A selective agonist of endothelin type B receptor, IRL 1620, stimulates cyclic GMP increase via nitric oxide formation in rat aorta.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Aorta, Thoracic; Arginine; Binding Sites; Calcium; Cyclic GMP; Cytosol; Drug Interactions; Endothelins; Endothelium, Vascular; Kinetics; Male; Membranes; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Peptide Fragments; Peptides, Cyclic; Rats; Rats, Wistar; Receptors, Endothelin; Stimulation, Chemical; Time Factors | 1993 |
Impaired nitric oxide-dependent cyclic guanosine monophosphate generation in glomeruli from diabetic rats. Evidence for protein kinase C-mediated suppression of the cholinergic response.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alkaloids; Amino Acid Oxidoreductases; Animals; Arginine; Calcimycin; Carbachol; Cyclic GMP; Diabetes Mellitus, Experimental; Female; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Isoquinolines; Kidney Glomerulus; Kinetics; Membrane Proteins; Myristoylated Alanine-Rich C Kinase Substrate; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phosphates; Phosphorylation; Piperazines; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Proteins; Rats; Rats, Sprague-Dawley; Staurosporine; Thromboxane A2 | 1994 |
Laminar flow stimulates ATP- and shear stress-dependent nitric oxide production in cultured bovine endothelial cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Animals; Aorta, Thoracic; Arginine; Calcium; Cattle; Cells, Cultured; Cyclic GMP; Egtazic Acid; Endothelium, Vascular; Fetus; Kinetics; Nitric Oxide; omega-N-Methylarginine; Stress, Mechanical | 1994 |
Organic nitrates and compounds that increase intraplatelet cyclic guanosine monophosphate (cGMP) levels enhance the antiaggregating effects of the stable prostacyclin analogue iloprost.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Diphosphate; Adult; Arginine; Blood Platelets; Collagen; Cyclic AMP; Cyclic GMP; Drug Synergism; Endothelium, Vascular; Epinephrine; Humans; Iloprost; Intracellular Fluid; Male; Nitroglycerin; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Factor 4; Second Messenger Systems | 1993 |
Induction of nitric oxide synthase by cyclic AMP in rat vascular smooth muscle cells.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Amino Acid Oxidoreductases; Animals; Aorta, Thoracic; Arginine; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Cycloheximide; Dactinomycin; Dexamethasone; Enzyme Induction; Kinetics; Muscle, Smooth, Vascular; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Wistar; RNA, Ribosomal | 1994 |
Endothelin (ET)-3 stimulates cyclic guanosine 3',5'-monophosphate production via ETB receptor by producing nitric oxide in isolated rat glomerulus, and in cultured rat mesangial cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Calmodulin; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Egtazic Acid; Endothelin Receptor Antagonists; Endothelins; Glomerular Mesangium; Guanylate Cyclase; Hemoglobins; In Vitro Techniques; Kidney Glomerulus; Kinetics; Male; Methylene Blue; Nicardipine; Nitric Oxide; omega-N-Methylarginine; Peptide Fragments; Peptides, Cyclic; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; Sulfonamides | 1994 |
Induction of nitric oxide release by interferon-gamma inhibits vasodilation and cyclic GMP increase in bovine isolated mesenteric arteries.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Cattle; Cyclic GMP; In Vitro Techniques; Interferon-gamma; Mesenteric Arteries; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Vasodilation | 1994 |
Smooth muscle cell responsiveness to nitrovasodilators in hypertensive and normotensive rats.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Base Sequence; Blotting, Northern; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Guanylate Cyclase; Hypertension; Male; Molecular Sequence Data; Muscle, Smooth, Vascular; Nitric Oxide; Nitroglycerin; Nitroprusside; Oligonucleotide Probes; omega-N-Methylarginine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA, Messenger; Vasodilation | 1994 |
Enhancement of cytosolic calcium, prostacyclin and nitric oxide by bradykinin and the ACE inhibitor ramiprilat in porcine brain capillary endothelial cells.
Topics: 1-Methyl-3-isobutylxanthine; 6-Ketoprostaglandin F1 alpha; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Bradykinin; Calcium; Capillaries; Cells, Cultured; Cerebrovascular Circulation; Cyclic GMP; Cytosol; Dose-Response Relationship, Drug; Endothelium, Vascular; Epoprostenol; Fura-2; Kinetics; Nitric Oxide; Nitroarginine; Ramipril; Swine | 1994 |
cGMP acts within cerebellar Purkinje cells to produce long term depression via mechanisms involving PKC and PKG.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Amino Acid Oxidoreductases; Animals; Arginine; Cyclic GMP; Electrophysiology; Enzyme Activation; Nitric Oxide Synthase; Nitroarginine; Potassium Chloride; Protein Kinase C; Purkinje Cells; Rats | 1994 |
Insulin increases guanosine-3',5'-cyclic monophosphate in human platelets. A mechanism involved in the insulin anti-aggregating effect.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Diphosphate; Adult; Amino Acid Oxidoreductases; Arginine; Blood Platelets; Collagen; Cyclic GMP; Female; Genistein; Guanylate Cyclase; Humans; Insulin; Isoflavones; Male; Methylene Blue; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein-Tyrosine Kinases; Radioimmunoassay; Recombinant Proteins | 1994 |
Different pial arteriolar responses to acetylcholine in the newborn and juvenile pig.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Aging; Animals; Animals, Newborn; Arginine; Arterioles; Calcimycin; Cerebrovascular Circulation; Cyclic GMP; Female; Male; Nitroarginine; Nitroprusside; Pia Mater; Swine | 1994 |
In vitro endotoxin exposure induces contractile dysfunction in adult rat cardiac myocytes.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Cell Survival; Cells, Cultured; Citrulline; Cyclic GMP; Dactinomycin; Electric Stimulation; Endotoxins; Heart; Kinetics; Male; Myocardial Contraction; Myocardium; NG-Nitroarginine Methyl Ester; Nitroprusside; Rats; Rats, Sprague-Dawley; Time Factors | 1994 |
Desulfated hirugen (hirudin 54-65) induces endothelium-dependent relaxation of porcine pulmonary arteries.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Sequence; Animals; Arginine; Atropine; Bradykinin; Calcium; Captopril; Cyclic GMP; Dinoprost; Endothelium, Vascular; Hirudins; Histamine; Indomethacin; Ketanserin; Methiothepin; Molecular Sequence Data; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Peptide Fragments; Phentolamine; Pulmonary Artery; Swine; Vasodilation | 1994 |
Tyrosine kinase inhibitors enhance cGMP production in rat pinealocytes.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Oxidoreductases; Animals; Arginine; Catechols; Cyclic AMP; Cyclic GMP; Genistein; Hydroquinones; Isoflavones; Isoproterenol; Male; Nitric Oxide Synthase; Nitriles; Norepinephrine; omega-N-Methylarginine; Pineal Gland; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Tyrphostins | 1995 |
Influence of nitric oxide synthase inhibition, nitric oxide and hydroperoxide on insulin release induced by various secretagogues.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Oxidoreductases; Animals; Arginine; Colforsin; Cyclic AMP; Cyclic GMP; Female; Glucose; Hydrogen Peroxide; Hydroxylamine; Hydroxylamines; In Vitro Techniques; Insulin; Islets of Langerhans; Mice; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peroxides; Reactive Oxygen Species; tert-Butylhydroperoxide; Vasodilator Agents | 1995 |
Nitric oxide synthesis in rat mesangial cells induced by cytokines.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Oxidoreductases; Animals; Arginine; Cells, Cultured; Chemotactic Factors; Cyclic GMP; Cycloheximide; Cytokines; Dactinomycin; Dexamethasone; Dose-Response Relationship, Drug; Gene Expression; Glomerular Mesangium; Interleukin-1; Interleukin-6; Interleukin-8; Kinetics; Male; Monocyte Chemoattractant Proteins; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Transcription, Genetic; Transforming Growth Factor beta | 1994 |
Role of cyclic nucleotides and nitric oxide in blood mononuclear cell IgE production stimulated by IL-4.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Arginine; B-Lymphocytes; Cholera Toxin; Cyclic AMP; Cyclic GMP; Drug Synergism; Epinephrine; Gene Expression Regulation; Humans; Immunoglobulin E; Interleukin-4; Leukocytes, Mononuclear; Molsidomine; Nitric Oxide; omega-N-Methylarginine; Receptors, IgE; Recombinant Fusion Proteins | 1995 |
Further characterization and comparison of inducible nitric oxide synthase in mouse, rat, and human hepatocytes.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Oxidoreductases; Animals; Arginine; Cells, Cultured; Cyclic GMP; Dexamethasone; Enzyme Induction; Gene Expression; Humans; Interferon-gamma; Interleukin-1; Interleukins; Isoenzymes; Lipopolysaccharides; Liver; Mice; Nitrates; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Rats; Recombinant Proteins; RNA, Messenger; Species Specificity; Tumor Necrosis Factor-alpha | 1995 |
Impairment of the priming effect of glucose on insulin secretion from isolated islets of aging rats.
Topics: 1-Methyl-3-isobutylxanthine; Aging; Animals; Arginine; Blood Glucose; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Kinetics; Male; Rats; Rats, Sprague-Dawley | 1995 |
Cytotoxicity of activated rat macrophages against syngeneic islet cells is arginine-dependent, correlates with citrulline and nitrite concentrations and is identical to lysis by the nitric oxide donor nitroprusside.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Cells, Cultured; Citrulline; Cyclic GMP; Female; Islets of Langerhans; Kinetics; Macrophage Activation; Macrophages; Male; Nitric Oxide; Nitrites; Nitroprusside; omega-N-Methylarginine; Rats; Rats, Wistar; Thionucleotides | 1993 |
Interleukin-1 beta effects on cyclic GMP and cyclic AMP in cultured rat islets of Langerhans-arginine-dependence and relationship to insulin secretion.
Topics: 1-Methyl-3-isobutylxanthine; Aminoquinolines; Animals; Antihypertensive Agents; Arginine; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Female; Insulin; Insulin Secretion; Interleukin-1; Islets of Langerhans; Kinetics; Molsidomine; NG-Nitroarginine Methyl Ester; Rats; Rats, Sprague-Dawley | 1993 |
B-cell insensitivity in vitro: reversal by diazoxide entails more than one event in stimulus-secretion coupling.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Barium; Cells, Cultured; Diazoxide; Dose-Response Relationship, Drug; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Perfusion; Potassium; Rats; Rats, Sprague-Dawley; Temperature; Time Factors | 1993 |
IL1 and TNF alpha induce cGMP formation in C6 astrocytoma cells via the nitridergic pathway.
Topics: 1-Methyl-3-isobutylxanthine; Arginine; Astrocytoma; Cyclic GMP; Interleukin-1; Nitrites; omega-N-Methylarginine; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1993 |
Nitric oxide-generating system as an autocrine mechanism in human polymorphonuclear leucocytes.
Topics: 1-Methyl-3-isobutylxanthine; Arginine; Biological Transport; Citrulline; Cyclic GMP; Endothelins; Humans; In Vitro Techniques; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitric Oxide; Nitroprusside; omega-N-Methylarginine | 1993 |
Reduction of nitric oxide producing activity associated with in vitro aging in cultured human umbilical vein endothelial cell.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Oxidoreductases; Animals; Arginine; Cell Division; Cell Line; Cells, Cultured; Cellular Senescence; Cerebellum; Cyclic GMP; Endothelium, Vascular; Epithelium; Humans; Kidney; Kinetics; Mice; Mice, Inbred Strains; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Tumor Cells, Cultured; Umbilical Veins | 1993 |
Antagonism by NG-nitro-L-arginine of L-glutamate-induced neurotoxicity in cultured neonatal rat cortical neurons. Prolonged application enhances neuroprotective efficacy.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Oxidoreductases; Animals; Animals, Newborn; Arginine; Cell Death; Cells, Cultured; Cerebral Cortex; Cyclic GMP; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Rats; Rats, Sprague-Dawley | 1993 |
Comparison of relaxation responses of detrusor strips from neuropathic and control patients.
Topics: 1-Methyl-3-isobutylxanthine; Adult; Aged; Arginine; Electric Stimulation; Female; Humans; Male; Middle Aged; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Spinal Dysraphism; Urinary Bladder, Neurogenic | 1995 |
Evidence for inducible nitric oxide synthase in spontaneously hypertensive rats.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Animals; Aorta, Thoracic; Arginine; Blood Pressure; Cyclic GMP; Enzyme Induction; Guanidines; In Vitro Techniques; Isoenzymes; Lipopolysaccharides; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitrites; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tumor Necrosis Factor-alpha | 1996 |
Apolipoprotein E inhibits platelet aggregation through the L-arginine:nitric oxide pathway. Implications for vascular disease.
Topics: 1-Methyl-3-isobutylxanthine; Apolipoproteins E; Arginine; Blood Platelets; Cholesterol; Cyclic AMP; Cyclic GMP; Dimyristoylphosphatidylcholine; Enzyme Inhibitors; Guanylate Cyclase; Humans; Lipoproteins, HDL; Membrane Lipids; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Phosphodiesterase Inhibitors; Platelet Aggregation; Platelet Aggregation Inhibitors; Quinoxalines | 1997 |
Nitric oxide and excitatory postsynaptic currents in immature rat sympathetic preganglionic neurons in vitro.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Cyclic GMP; Electric Stimulation; Evoked Potentials; Ganglia, Sympathetic; Hemoglobins; Immunohistochemistry; Nerve Fibers; Neurons; Nitric Oxide Synthase; Nitroarginine; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Spinal Cord; Synaptic Transmission | 1997 |
Inducible nitric oxide synthase augments injury elicited by oxidative stress in rat cardiac myocytes.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Animals, Newborn; Arginine; Cells, Cultured; Cyclic GMP; Enzyme Induction; Glutathione Peroxidase; Heart; Heart Injuries; Kinetics; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Oligonucleotides, Antisense; Oxidative Stress; Penicillamine; Rats; S-Nitroso-N-Acetylpenicillamine | 1998 |
Arginase activity is modulated by IL-4 and HOArg in nephritic glomeruli and mesangial cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginase; Arginine; Cholera Toxin; Cyclic AMP; Glomerular Mesangium; Interleukin-1; Interleukin-4; Isoenzymes; Kidney Glomerulus; Macrophages, Peritoneal; Male; Nephritis; Nitrites; Rats; Rats, Inbred Lew | 1998 |
Factors contributing to differences in the regulation of cGMP in isolated porcine pulmonary vessels.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Blotting, Western; Carbon Radioisotopes; Citrulline; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Female; Guanylate Cyclase; Male; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Pulmonary Veins; Purinones; Swine | 1998 |
Modulation by nitric oxide of gastric acid secretion in toads.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Bufo marinus; Carbachol; Enzyme Inhibitors; Gastric Acid; Gastric Mucosa; Histamine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Parasympathomimetics; Parietal Cells, Gastric; Pentagastrin; Phosphodiesterase Inhibitors; Protons | 1998 |
Effects of cryopreservation on in vitro and in vivo long-term function of human islets.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Cryopreservation; Diabetes Mellitus, Experimental; Glucagon; Glucose; Glucose Tolerance Test; Humans; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Islets of Langerhans Transplantation; Male; Mice; Mice, Nude; Reference Values; Time Factors; Transplantation, Heterologous | 1999 |
Investigation of gastroprotective compounds at subcellular level in isolated gastric mucosal cells.
Topics: 1-Methyl-3-isobutylxanthine; 16,16-Dimethylprostaglandin E2; Animals; Arginine; Atropine; Carbachol; Catechols; Cell Membrane; Cell Nucleus; Cell Survival; Cells, Cultured; Drug Evaluation, Preclinical; Ethanol; Gastric Mucosa; Gastrointestinal Agents; Histamine; Mitochondria; Morpholines; Pentanones; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds | 2000 |
Human immunodeficiency virus type 1 Tat protein decreases cyclic AMP synthesis in rat microglia cultures.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Antibodies, Monoclonal; Apoptosis; Arginine; Astrocytes; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Energy Metabolism; Enzyme Activation; Gene Products, tat; GTP-Binding Protein alpha Subunits, Gi-Go; HIV-1; Hydrazines; Isoproterenol; Lipopolysaccharides; Microglia; Nerve Degeneration; NF-kappa B; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroso Compounds; Peptides; Pertussis Toxin; Rats; Rats, Wistar; Recombinant Fusion Proteins; Second Messenger Systems; tat Gene Products, Human Immunodeficiency Virus; Tosylphenylalanyl Chloromethyl Ketone; Virulence Factors, Bordetella | 2001 |
The role of cyclic AMP in the pathogenesis of glucose desensitization in rat pancreatic islets.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Bucladesine; Cells, Cultured; Culture Media, Conditioned; Cyclic AMP; Diazoxide; Drug Tolerance; Female; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Rats; Rats, Wistar | 2001 |
Dynamics of nitric oxide during simulated ischaemia-reperfusion in rat striatal slices measured using an intrinsic biosensor, soluble guanylyl cyclase.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Biosensing Techniques; Brain Ischemia; Cyclic GMP; Guanylate Cyclase; NADPH Dehydrogenase; Neostriatum; Neurons; Nitric Oxide; Nitric Oxide Synthase; Phosphodiesterase Inhibitors; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reperfusion Injury | 2002 |
Nitric oxide regulates the phosphorylation of the threonine-glutamine-tyrosine motif in proteins of human spermatozoa during capacitation.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Motifs; Arginine; Bucladesine; Drug Combinations; Enzyme Inhibitors; Glutamine; Humans; Immunologic Techniques; Male; Molecular Weight; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrogen Oxides; Phosphorylation; Proteins; Sperm Capacitation; Spermatozoa; Spermine; Threonine; Tyrosine | 2003 |
Islet amyloid polypeptide inhibits glucagon release and exerts a dual action on insulin release from isolated islets.
Topics: 1-Methyl-3-isobutylxanthine; Amyloid; Animals; Arginine; Carbachol; Cholinergic Agonists; Culture Media; Female; Glucagon; Glucose; Insulin; Insulin Secretion; Islet Amyloid Polypeptide; Islets of Langerhans; Mice; Phosphodiesterase Inhibitors | 2003 |
Cardiac enkephalins attenuate vagal bradycardia: interactions with NOS-1-cGMP systems in canine sinoatrial node.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Bradycardia; Cyclic GMP; Dogs; Dose-Response Relationship, Drug; Enkephalin, Methionine; Enzyme Inhibitors; Indazoles; Methacholine Chloride; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Parasympathomimetics; Penicillamine; Phosphodiesterase Inhibitors; Sinoatrial Node; Vagus Nerve | 2003 |
Effects of ghrelin on insulin and glucagon secretion: a study of isolated pancreatic islets and intact mice.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Blood Glucose; Carbachol; Dose-Response Relationship, Drug; Female; Ghrelin; Glucagon; Glucose; Glucose Tolerance Test; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Pancreas; Peptide Hormones; Signal Transduction; Time Factors | 2004 |
Pathological implications of iNOS expression in central white matter: an ex vivo study of optic nerves from rats with experimental allergic encephalomyelitis.
Topics: 1-Methyl-3-isobutylxanthine; Action Potentials; Animals; Arginine; Biomarkers; CD11b Antigen; CD2 Antigens; Cyclic GMP; DEET; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Encephalomyelitis, Autoimmune, Experimental; Female; Guanylate Cyclase; Guinea Pigs; Hydrazines; Immunohistochemistry; Macrophages; Microscopy, Electron, Transmission; Myelin Basic Protein; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Optic Chiasm; Optic Nerve; Ornithine; Phosphodiesterase Inhibitors; Rats; Rats, Inbred Lew; Time Factors | 2005 |
Tyrosine phosphorylation of a 38-kDa capacitation-associated buffalo (Bubalus bubalis) sperm protein is induced by L-arginine and regulated through a cAMP/PKA-independent pathway.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Bucladesine; Buffaloes; Cell Survival; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluorescent Antibody Technique; Heparin; Isoquinolines; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Osmolar Concentration; Phosphodiesterase Inhibitors; Phosphoproteins; Phosphorylation; Protein Kinase Inhibitors; Sperm Capacitation; Sperm Motility; Spermatozoa; Sulfonamides; Tyrosine | 2008 |
The Phosphodiesterase Inhibitor IBMX Blocks the Potassium Channel THIK-1 from the Extracellular Side.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Binding Sites; CHO Cells; Cricetulus; Cyclic AMP-Dependent Protein Kinases; Humans; Mutation; Patch-Clamp Techniques; Potassium Channels, Tandem Pore Domain; Rats; Xenopus | 2020 |