arecoline and arecaidine

arecoline has been researched along with arecaidine in 60 studies

Research

Studies (60)

Timeframe	Studies, this research(%)	All Research%
pre-1990	6 (10.00)	18.7374
1990's	8 (13.33)	18.2507
2000's	22 (36.67)	29.6817
2010's	22 (36.67)	24.3611
2020's	2 (3.33)	2.80

Authors

Authors	Studies
Bellman, K; Knegtel, RM; Settimo, L	1
Brand, SJ; Curtis, DR; Johnston, GA; Lodge, D	1
Bergmeier, SC; Coughenour, LL; Davis, RE; Hershenson, FM; Kester, JA; Marriott, JG; McKee, JS; Moos, WH; Schwarz, RD; Tecle, H	1
Arvidson, K; Bartsch, H; Grafström, RC; Liu, Y; Nair, J; Sundqvist, K	1
Harvey, W; Meghji, S; Scutt, A	1
Panigrahi, GB; Rao, AR	1
Chen, CC; Huang, JF; Tsai, CC	1
Classen, M; Schaffer, K; Schepp, W; Schusdziarra, V; Wegner, U; Weigert, N	1
de Miranda, CM; Grobler-Rabie, AF; Olivier, A; van der Bijl, P; van Wyk, CW	1
Chaudhuri, L; Ganguly, DK	1
Chen, YK; Huang, YL; Lai, DL; Lin, LM	1
Peng, CH; Wang, CK	1
Ma, RH; Shieh, TY; Tsai, CC	1
Ahmed, A; Hengesteg, A; Robbins, KT; Wani, MK; Yarber, RH	1
Stander, IA; Van Eyk, AD; Van Wyk, CW	1
Bernardini, N; Reeh, PW; Sauer, SK	1
van der Bijl, P; van Eyk, AD	2
Drake, MJ; Gillespie, JI; Harvey, IJ	2
NAKAJIMA, H; RUMPF, P; THUILLIER, G; THUILLIER, J	1
CHILTON, J; STENLAKE, JB	1
Dussor, GO; Flores, CM; Hargreaves, KM; Helesic, G	1
Bukharaeva, EA; Magazanik, LG; Nikolsky, EE; Samigullin, D; Vyskocil, F	1
Drake, MJ; Gillespie, JI; Lagou, M	1
Andersson, KE; Drake, MJ; Gillespie, JI; Kirkwood, T; Lagou, M	1
Lai, KC; Lee, TC	1
Chen, C; Giri, S; Gonzalez, FJ; Idle, JR; Krausz, KW; Zabriskie, TM	1
De Ridder, D; Gevaert, T; Ost, D	1
Drake, MJ; Gillespie, J; Harvey, I; Kirkwood, T; Lagou, M	1
Andersson, KE; Drake, M; Gillespie, J; Harvey, I; Hedlund, P; Lagou, M	1
Giri, S; Gonzalez, FJ; Idle, JR; Krausz, KW	1
Finney, SM; Gillespie, JI; Stewart, LH	2
Ikeda, Y; Kanai, A	1
Chang, CK; Cheng, JT; Cheng, KC; Juang, SW; Kou, DH; Liu, IM; Tong, YC	1
Feng, CH; Lu, CY	1
Chang, YZ; Chao, MR; Hu, CW; Wang, HW	1
Coppola, M; Mondola, R	1
Gao, W; Guo, D; Han, J; Liang, Y; Ren, Z; Wang, B; Yang, D; Yuan, J; Zeng, W	1
Calogero, A; Di Bari, M; Fabbiano, C; Ferretti, M; Ponti, D; Tata, AM	1
Khan, I; Kondaiah, P; Kumar, N; Narra, S; Pant, I	1
Chang, MC; Cheng, RH; Hahn, LJ; Ho, YS; Hsien, HC; Jeng, JH; Jeng, PY; Lin, LD; Wang, TM; Wu, HL	1
de Wachter, SG; Rahnama'i, MS; van Kerrebroeck, PE; van Koeveringe, GA	1
Brandsch, M; Laug, L; Markwardt, F; Thondorf, I; Voigt, V; Zebisch, K	1
Calogero, A; Castigli, E; Conte, C; Di Bari, M; Fabbiano, C; Ferretti, M; Ponti, D; Raco, A; Ricordy, R; Ruggieri, P; Sciaccaluga, M; Tata, AM	1
Catacuzzeno, L; De Angelis, F; Fioretti, B; Franciolini, F; Marinelli, S; Pavone, F; Tata, AM	1
Avallone, B; Costantino, M; De Stefano, ME; Loreti, S; Magnaghi, V; Pisano, A; Talora, C; Tata, AM; Uggenti, C	1
Calogero, A; Carbone, A; Coccia, A; De Falco, E; Di Bari, M; Pacini, L; Pastore, AL; Petrozza, V; Ponti, D; Siciliano, C; Tata, AM	1
Lu, TL; Mao, CQ; Mao, SH; Tang, LJ; Wu, H; Yu, HL	1
Ali, S; Atif, M; Hassona, Y; James, EL; Lone, MA; Parkinson, EK; Pitiyage, GN; Prime, SS; Rehman, A	1
Franke, AA; Lai, JF; Li, X	1
De Wachter, S; Eastham, J; Gillespie, J; Persyn, S; Wyndaele, JJ	1
Cai, B; Tang, L; Wang, K; Wu, H; Yin, Y; Yu, H; Zhang, C; Zhang, X	1
Horenstein, NA; Papke, RL; Quadri, M; Shoaib, M; Stokes, C	1
Huang, L; Li, Y; Lu, Y; Pan, H; Shi, F; Zhou, X	1
Chiu, CF; Gritz, ER; Hsu, WY; Lai, CC; Lam, C; Li, CI; Li, TC; Lin, CC; Liu, CS; Lu, IY; Tamí-Maury, I; Tsai, MH	1
Grünhofer, P; Schreiber, L; Wan, Y; Wang, S; Wu, J; Yuan, L; Zhang, H	1
Faroni, A; Piovesana, R; Reid, AJ; Tata, AM	1
Chong, KW; Chua, NQE; Cirillo, N; Dang, S; Davis, A; Prime, SS; Zhang, P	1

Reviews

2 review(s) available for arecoline and arecaidine

Article	Year
Potential action of betel alkaloids on positive and negative symptoms of schizophrenia: a review. Nordic journal of psychiatry, 2012, Volume: 66, Issue:2 Topics: Alkaloids; Areca; Arecoline; Cholinergic Agents; Humans; Male; Phytotherapy; Schizophrenia; Schizophrenic Psychology	2012
Molecular Mechanisms of Malignant Transformation of Oral Submucous Fibrosis by Different Betel Quid Constituents-Does Fibroblast Senescence Play a Role? International journal of molecular sciences, 2022, Jan-31, Volume: 23, Issue:3 Topics: Areca; Arecoline; Carcinoma, Squamous Cell; Disease Progression; Humans; Mouth Neoplasms; Nicotinic Acids; Oral Submucous Fibrosis; Plant Extracts	2022

Other Studies

58 other study(ies) available for arecoline and arecaidine

Article	Year
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Effects of the Areca nut constituents arecaidine and guvacine on the action of GABA in the cat central nervous system. Brain research, 1977, Nov-18, Volume: 136, Issue:3 Topics: Action Potentials; Alanine; Aminobutyrates; Animals; Areca; Arecoline; Bicuculline; Cats; Cerebellum; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Mice; Neural Inhibition; Nicotinic Acids; Nipecotic Acids; Plant Extracts; Plants, Medicinal; Purkinje Cells; Reflex, Monosynaptic; Seizures; Spinal Cord	1977
Cholinergic agents: effect of methyl substitution in a series of arecoline derivatives on binding to muscarinic acetylcholine receptors. Journal of pharmaceutical sciences, 1992, Volume: 81, Issue:10 Topics: Animals; Arecoline; Choline; Dioxolanes; Muscarinic Antagonists; Parasympathomimetics; Quinuclidinyl Benzilate; Rats; Receptors, Muscarinic; Structure-Activity Relationship; Tritium	1992
Cytotoxic and genotoxic effects of areca nut-related compounds in cultured human buccal epithelial cells. Cancer research, 1989, Oct-01, Volume: 49, Issue:19 Topics: Arecoline; Colony-Forming Units Assay; DNA Damage; Epithelium; Humans; Mouth Mucosa; Nitroso Compounds	1989
Stimulation of human fibroblast collagen synthesis in vitro by gamma-aminobutyric acid. Biochemical pharmacology, 1987, Apr-15, Volume: 36, Issue:8 Topics: Arecoline; Cell Division; Cells, Cultured; Collagen; Fibroblasts; gamma-Aminobutyric Acid; Humans	1987
Induction of in vivo sister chromatid exchanges by arecaidine, a betel nut alkaloid, in mouse bone-marrow cells. Cancer letters, 1984, Volume: 23, Issue:2 Topics: Animals; Areca; Arecoline; Bone Marrow; Crossing Over, Genetic; Dose-Response Relationship, Drug; Female; Injections, Intraperitoneal; Male; Mice; Mice, Inbred Strains; Nuts; Plants, Medicinal; Sister Chromatid Exchange; Time Factors	1984
In vitro production of interleukin-6 by human gingival, normal buccal mucosa, and oral submucous fibrosis fibroblasts treated with betel-nut alkaloids. Gaoxiong yi xue ke xue za zhi = The Kaohsiung journal of medical sciences, 1995, Volume: 11, Issue:11 Topics: Adult; Arecoline; Cells, Cultured; Fibroblasts; Gingiva; Humans; Interleukin-6; Middle Aged; Mouth Mucosa; Oral Submucous Fibrosis; Parasympathomimetics	1995
Functional characterization of a muscarinic receptor stimulating gastrin release from rabbit antral G-cells in primary culture. European journal of pharmacology, 1994, Nov-03, Volume: 264, Issue:3 Topics: Animals; Arecoline; Atropine; Benzodiazepinones; Carbachol; Cell Adhesion; Cell Separation; Cells, Cultured; Gastrins; Immunohistochemistry; Male; Muscarinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Pyloric Antrum; Rabbits; Receptors, Muscarinic	1994
Observations on the effect of areca nut extracts on oral fibroblast proliferation. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 1994, Volume: 23, Issue:4 Topics: Areca; Arecoline; Cell Death; Cell Division; Cell Line; Cell Survival; Chromatography, High Pressure Liquid; Cooking; Dose-Response Relationship, Drug; Fibroblasts; Humans; Mouth Mucosa; Plant Extracts; Plants, Medicinal	1994
Involvement of gamma-aminobutyric acid in the stimulatory effect of metoclopramide on gastrointestinal motility. Life sciences, 1994, Volume: 54, Issue:4 Topics: Aminobutyrates; Animals; Arecoline; Bicuculline; Drug Interactions; Ethylenediamines; gamma-Aminobutyric Acid; Gastrointestinal Motility; Guinea Pigs; Ileum; Male; Metoclopramide; Muscle Contraction; Myenteric Plexus; Neuromuscular Junction; Neurotransmitter Uptake Inhibitors; Sensitivity and Specificity; Stimulation, Chemical	1994
Minimal arecaidine concentrations showing a promotion effect during DMBA-induced hamster cheek pouch carcinogenesis. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 1996, Volume: 25, Issue:2 Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Arecoline; Carcinogens; Carcinoma, Squamous Cell; Cheek; Cocarcinogenesis; Cricetinae; Dose-Response Relationship, Drug; Drug Synergism; Leukoplakia, Oral; Male; Mesocricetus; Mouth Neoplasms; Papilloma; Stomatitis	1996
The mutagenicities of alkaloids and N-nitrosoguvacoline from betel quid. Mutation research, 1996, Aug-08, Volume: 360, Issue:3 Topics: Alkaloids; Animals; Areca; Arecoline; Carcinogens; Hydrogen-Ion Concentration; Liver; Mutagenicity Tests; Mutagens; Nicotinic Acids; Nitroso Compounds; Phenols; Plant Extracts; Plants, Medicinal; Rats; Salmonella typhimurium; Sodium Nitrite; Taiwan	1996
Deficiency in collagen and fibronectin phagocytosis by human buccal mucosa fibroblasts in vitro as a possible mechanism for oral submucous fibrosis. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 1999, Volume: 28, Issue:2 Topics: Administration, Topical; Adolescent; Adult; Anti-Inflammatory Agents; Areca; Arecoline; Cells, Cultured; Child; Collagen; Female; Fibroblasts; Fibronectins; Glucocorticoids; Humans; Male; Mouth Mucosa; Oral Submucous Fibrosis; Phagocytosis; Plants, Medicinal; Triamcinolone	1999
Cancer induction in the DMBA hamster cheek pouch: a modified technique using a promoter. The Laryngoscope, 2001, Volume: 111, Issue:2 Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Arecoline; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cheek; Cricetinae; Disease Models, Animal; Mesocricetus; Mouth Mucosa; Mouth Neoplasms; Sutures	2001
Diffusion of reduced arecoline and arecaidine through human vaginal and buccal mucosa. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2001, Volume: 30, Issue:4 Topics: Adolescent; Adult; Analysis of Variance; Areca; Arecoline; Cholinergic Agonists; Diffusion; Female; Humans; Male; Middle Aged; Mouth Mucosa; Mucous Membrane; Permeability; Plants, Medicinal; Statistics as Topic; Time Factors; Vagina	2001
Muscarinic M2 receptors inhibit heat-induced CGRP release from isolated rat skin. Neuroreport, 2001, Aug-08, Volume: 12, Issue:11 Topics: Acetylcholine; Animals; Arecoline; Calcitonin Gene-Related Peptide; Dose-Response Relationship, Drug; Female; Hot Temperature; In Vitro Techniques; Male; Muscarine; Muscarinic Agonists; Nicotine; Nicotinic Agonists; Nociceptors; Rats; Receptor, Muscarinic M2; Receptors, Muscarinic; Skin	2001
Areca nut extract lowers the permeability of vaginal mucosa to reduced arecoline and arecaidine. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2001, Volume: 30, Issue:9 Topics: Adult; Aged; Analysis of Variance; Areca; Arecoline; Diffusion Chambers, Culture; Female; Humans; Kinetics; Middle Aged; Mucous Membrane; Permeability; Plant Extracts; Statistics, Nonparametric; Vagina	2001
Autonomous activity in the isolated guinea pig bladder. Experimental physiology, 2003, Volume: 88, Issue:1 Topics: Animals; Arecoline; Atropine; Female; Guinea Pigs; Homeostasis; In Vitro Techniques; Movement; Muscle Contraction; Muscle, Smooth; Pressure; Tetrodotoxin; Urinary Bladder; Urination	2003
Agonist- and nerve-induced phasic activity in the isolated whole bladder of the guinea pig: evidence for two types of bladder activity. Experimental physiology, 2003, Volume: 88, Issue:3 Topics: Anesthetics, Local; Animals; Arecoline; Atropine; Carbachol; Cholinergic Agonists; Electric Stimulation; Female; Guinea Pigs; Hexamethonium; Lobeline; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Nicotinic Agonists; Nicotinic Antagonists; Stimulation, Chemical; Tetrodotoxin; Urinary Bladder	2003
Comparative in vitro permeability of human vaginal, small intestinal and colonic mucosa. International journal of pharmaceutics, 2003, Aug-11, Volume: 261, Issue:1-2 Topics: Adult; Aged; Arecoline; Colon; Diffusion Chambers, Culture; Estradiol; Female; Humans; In Vitro Techniques; Intestinal Mucosa; Intestine, Small; Male; Membranes; Middle Aged; Mouth Mucosa; Mucous Membrane; Permeability; Vagina	2003
[Effect on the central nervous system of simplified structural analogs of LSD 25 derived from arecaidine amides]. Comptes rendus des seances de la Societe de biologie et de ses filiales, 1958, Volume: 152, Issue:1 Topics: Amides; Anesthetics, Local; Arecoline; Central Nervous System; Lysergic Acid Diethylamide; Niacin; Nicotinic Acids	1958
Dissociation constants of some compounds related to lysergic acid. II. Ergometrine, ergometrinine and alkanolamides of 3-dimethylaminopropionic acid, 1-methylhexahydronicotinic acid and arecaidine. The Journal of pharmacy and pharmacology, 1962, Volume: 14 Topics: Arecoline; Cardiovascular Agents; Ergonovine; Ergot Alkaloids; Lysergic Acid	1962
Cholinergic modulation of nociceptive responses in vivo and neuropeptide release in vitro at the level of the primary sensory neuron. Pain, 2004, Volume: 107, Issue:1-2 Topics: Acetylcholine; Analysis of Variance; Animals; Arecoline; Atropine; Behavior, Animal; Bungarotoxins; Calcitonin Gene-Related Peptide; Capsaicin; Cell Count; Disinfectants; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Formaldehyde; Gallamine Triethiodide; Gene Expression Regulation; Grooming; In Situ Hybridization; In Vitro Techniques; Male; Mecamylamine; Mouth Mucosa; Muscarinic Antagonists; Neurons, Afferent; Nicotinic Antagonists; Pain; Pain Measurement; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptors, Drug; RNA, Messenger; Time; Trigeminal Ganglion	2004
Cholinergic regulation of the evoked quantal release at frog neuromuscular junction. The Journal of physiology, 2004, Oct-01, Volume: 560, Issue:Pt 1 Topics: Acetylcholine; Action Potentials; Animals; Arecoline; Carbachol; Cholinergic Agonists; Diamines; Motor Neurons; Muscarinic Agonists; Muscarinic Antagonists; Neural Conduction; Neuromuscular Junction; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Oxotremorine; Parasympatholytics; Pirenzepine; Rana ridibunda; Receptors, Muscarinic; Synaptic Transmission; Tubocurarine	2004
Volume-induced effects on the isolated bladder: a possible local reflex. BJU international, 2004, Volume: 94, Issue:9 Topics: Animals; Arecoline; Autonomic Nervous System; Carbachol; Electrophysiology; Female; Guinea Pigs; In Vitro Techniques; Muscarinic Agonists; Pressure; Reflex, Stretch; Tetrodotoxin; Urinary Bladder; Vesico-Ureteral Reflux	2004
Bladder volume alters cholinergic responses of the isolated whole mouse bladder. The Journal of urology, 2006, Volume: 175, Issue:2 Topics: Animals; Arecoline; Female; In Vitro Techniques; Mice; Mice, Inbred C57BL; Muscarinic Agonists; Urinary Bladder	2006
Genetic damage in cultured human keratinocytes stressed by long-term exposure to areca nut extracts. Mutation research, 2006, Jul-25, Volume: 599, Issue:1-2 Topics: Apoptosis; Areca; Arecoline; Cell Line; Cell Proliferation; DNA Damage; Glutathione; Guanosine; Humans; Hypoxanthine Phosphoribosyltransferase; Keratinocytes; Micronucleus Tests; Mutation; Plant Extracts; Reactive Oxygen Species	2006
A metabolomic approach to the metabolism of the areca nut alkaloids arecoline and arecaidine in the mouse. Chemical research in toxicology, 2006, Volume: 19, Issue:6 Topics: Animals; Areca; Arecoline; Gas Chromatography-Mass Spectrometry; Male; Mice; Molecular Structure	2006
Comparison study of autonomous activity in bladders from normal and paraplegic rats. Neurourology and urodynamics, 2006, Volume: 25, Issue:4 Topics: Animals; Arecoline; Carbachol; Cholinergic Agonists; Female; Muscarinic Agonists; Muscle Contraction; Paraplegia; Pressure; Rats; Rats, Wistar; Urinary Bladder; Urinary Bladder, Neurogenic; Urodynamics	2006
Muscarinic stimulation of the mouse isolated whole bladder: physiological responses in young and ageing mice. Autonomic & autacoid pharmacology, 2006, Volume: 26, Issue:3 Topics: Age Factors; Aging; Animals; Arecoline; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Mice; Mice, Inbred C57BL; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Physostigmine; Receptors, Muscarinic; Urinary Bladder; Urination Disorders	2006
Muscarinic stimulation of the rat isolated whole bladder: pathophysiological models of detrusor overactivity. Autonomic & autacoid pharmacology, 2006, Volume: 26, Issue:3 Topics: Animals; Arecoline; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hypertension; Male; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Rats, Wistar; Urinary Bladder; Urinary Bladder Neck Obstruction	2006
The metabolomics of (+/-)-arecoline 1-oxide in the mouse and its formation by human flavin-containing monooxygenases. Biochemical pharmacology, 2007, Feb-15, Volume: 73, Issue:4 Topics: Acetylcysteine; Administration, Oral; Animals; Arecoline; Chromatography, Liquid; Cyclic N-Oxides; Cytochrome P-450 Enzyme System; Dogs; Humans; Kinetics; Male; Mass Spectrometry; Metabolic Networks and Pathways; Mice; Molecular Structure; Nipecotic Acids; Oxygenases; Piperidines; Recombinant Proteins; Stereoisomerism; Sulfhydryl Compounds; Urinalysis	2007
Cholinergic activation of phasic activity in the isolated bladder: possible evidence for M3- and M2-dependent components of a motor/sensory system. BJU international, 2007, Volume: 100, Issue:3 Topics: Animals; Arecoline; Benzofurans; Carbachol; Cholinergic Agonists; Female; Guinea Pigs; Muscarinic Agonists; Piperidines; Pyrrolidines; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Urinary Bladder; Urination	2007
Urotheliogenic modulation of intrinsic activity in spinal cord-transected rat bladders: role of mucosal muscarinic receptors. American journal of physiology. Renal physiology, 2008, Volume: 295, Issue:2 Topics: Animals; Arecoline; Calcium Channel Blockers; Disease Models, Animal; Female; Mucous Membrane; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Nifedipine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Spinal Cord; Urinary Bladder; Urinary Bladder, Overactive; Urothelium	2008
Role of hyperglycaemia in the pathogenesis of hypotension observed in type-1 diabetic rats. International journal of experimental pathology, 2008, Volume: 89, Issue:4 Topics: Animals; Arecoline; Baroreflex; Cell Line; Cholinergic Agonists; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Gene Expression; Glucose; Hyperglycemia; Hypotension; Insulin; Male; Phenylephrine; Phlorhizin; Rats; Rats, Wistar; Receptor, Muscarinic M2; RNA, Messenger	2008
Volume-induced responses in the isolated bladder: evidence for excitatory and inhibitory elements. BJU international, 2008, Volume: 102, Issue:9 Topics: Animals; Arecoline; Autonomic Nervous System; Female; Guinea Pigs; Urinary Bladder	2008
A new matrix for analyzing low molecular mass compounds and its application for determination of carcinogenic areca alkaloids by matrix-assisted laser desorption ionization time-of-flight mass spectrometry. Analytica chimica acta, 2009, Sep-07, Volume: 649, Issue:2 Topics: Arecoline; Carcinogens; Humans; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization	2009
High-throughput simultaneous analysis of five urinary metabolites of areca nut and tobacco alkaloids by isotope-dilution liquid chromatography-tandem mass spectrometry with on-line solid-phase extraction. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2010, Volume: 19, Issue:10 Topics: Adult; Areca; Arecoline; Chromatography, High Pressure Liquid; Cotinine; Cross-Sectional Studies; Humans; Male; Middle Aged; Nicotiana; Nicotine; Smoking; Solid Phase Extraction; Tandem Mass Spectrometry; Young Adult	2010
Alkaloids from areca (betel) nuts and their effects on human sperm motility in vitro. Journal of food science, 2012, Volume: 77, Issue:4 Topics: Adult; Alkaloids; Areca; Arecoline; China; Chromatography, High Pressure Liquid; Food, Preserved; Humans; Image Processing, Computer-Assisted; Infertility, Male; Male; Nicotinic Acids; Nuts; Osmolar Concentration; Plant Epidermis; Semen Analysis; Sperm Motility; Spermatozoa; Young Adult	2012
M2 muscarinic receptors inhibit cell proliferation in human glioblastoma cell lines. Life sciences, 2012, Nov-27, Volume: 91, Issue:21-22 Topics: Arecoline; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Receptor, Muscarinic M2; Reverse Transcriptase Polymerase Chain Reaction	2012
Activation of TGF-β pathway by areca nut constituents: a possible cause of oral submucous fibrosis. PloS one, 2012, Volume: 7, Issue:12 Topics: Areca; Arecoline; Biomarkers; Cells, Cultured; Collagen; Fibroblasts; Gene Expression Profiling; Gingiva; Humans; Keratinocytes; Mastication; Nuts; Oligonucleotide Array Sequence Analysis; Oral Submucous Fibrosis; Phosphorylation; Plant Extracts; Plants, Toxic; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Smad2 Protein; Transforming Growth Factor beta; Up-Regulation	2012
Areca nut-induced buccal mucosa fibroblast contraction and its signaling: a potential role in oral submucous fibrosis--a precancer condition. Carcinogenesis, 2013, Volume: 34, Issue:5 Topics: Areca; Arecoline; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cells, Cultured; Fibroblasts; Humans; Inositol 1,4,5-Trisphosphate Receptors; Mouth Mucosa; Mouth Neoplasms; Myosin Light Chains; Nuts; Oral Submucous Fibrosis; Phosphorylation; Plant Extracts; Precancerous Conditions; Reactive Oxygen Species; Signal Transduction	2013
The effect of indomethacin on the muscarinic induced contractions in the isolated normal guinea pig urinary bladder. BMC urology, 2013, Feb-07, Volume: 13 Topics: Animals; Arecoline; Cyclooxygenase Inhibitors; Dinoprostone; Guinea Pigs; Indomethacin; Male; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Urinary Bladder	2013
Transport of the areca nut alkaloid arecaidine by the human proton-coupled amino acid transporter 1 (hPAT1). The Journal of pharmacy and pharmacology, 2013, Volume: 65, Issue:4 Topics: Amino Acid Transport Systems; Animals; Areca; Arecoline; Binding, Competitive; Biological Transport; Caco-2 Cells; Drugs, Investigational; Enterocytes; Female; GABA Agonists; GABA Uptake Inhibitors; HeLa Cells; Humans; Intestinal Absorption; Isonicotinic Acids; Kinetics; Nicotinic Acids; Nuts; Oocytes; Recombinant Proteins; Symporters; Xenopus laevis	2013
M2 receptor activation inhibits cell cycle progression and survival in human glioblastoma cells. Journal of cellular and molecular medicine, 2013, Volume: 17, Issue:4 Topics: Antineoplastic Agents; Apoptosis; Arecoline; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Glioblastoma; Humans; Inhibitory Concentration 50; Muscarinic Agonists; Muscarinic Antagonists; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Receptor, Muscarinic M2; Signal Transduction	2013
M2 receptors exert analgesic action on DRG sensory neurons by negatively modulating VR1 activity. Journal of cellular physiology, 2014, Volume: 229, Issue:6 Topics: Animals; Arecoline; Cells, Cultured; Cholinergic Agonists; Gene Expression Regulation; Hyperalgesia; Injections, Intraperitoneal; Male; Mice; Mice, Knockout; Nerve Growth Factor; Patch-Clamp Techniques; Protein Kinase C-epsilon; Rats; Rats, Wistar; Receptor, Muscarinic M2; Sensory Receptor Cells; TRPV Cation Channels	2014
M2 muscarinic receptor activation regulates Schwann cell differentiation and myelin organization. Developmental neurobiology, 2014, Volume: 74, Issue:7 Topics: Animals; Arecoline; Axons; Cells, Cultured; Mice, Knockout; Myelin Proteins; Myelin Sheath; Nerve Degeneration; Neurogenesis; Peripheral Nervous System Agents; Rats, Wistar; Receptor, Muscarinic M2; Receptor, Muscarinic M4; RNA, Messenger; Schwann Cells; Sciatic Nerve; Signal Transduction; Transcription Factors	2014
M2muscarinic receptors inhibit cell proliferation and migration in urothelial bladder cancer cells. Cancer biology & therapy, 2014, Volume: 15, Issue:11 Topics: Arecoline; Biopsy; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Gene Expression; Humans; Muscarinic Antagonists; Neoplasm Grading; Receptor, Muscarinic M2; Urinary Bladder Neoplasms	2014
[Optimization of Preparation of Cutting-processed Arecae Pericarpium with Multi-index Orthogonal Method]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2014, Volume: 37, Issue:12 Topics: Alkaloids; Areca; Arecoline; Drugs, Chinese Herbal; Nicotinic Acids	2014
Areca nut alkaloids induce irreparable DNA damage and senescence in fibroblasts and may create a favourable environment for tumour progression. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2016, Volume: 45, Issue:5 Topics: Areca; Arecoline; beta-Galactosidase; Cell Cycle; Cell Line; Cellular Senescence; Disease Progression; DNA Damage; Fibroblasts; Humans; Matrix Metalloproteinase 2; Mouth Neoplasms; Oral Submucous Fibrosis; Transforming Growth Factor beta; Tumor Suppressor p53-Binding Protein 1	2016
Pilot study of the pharmacokinetics of betel nut and betel quid biomarkers in saliva, urine, and hair of betel consumers. Drug testing and analysis, 2016, Volume: 8, Issue:10 Topics: Alkaloids; Areca; Arecoline; Biomarkers; Body Fluids; Hair; Humans; Mass Spectrometry; Nicotinic Acids; Pilot Projects; Saliva	2016
The actions of isoprenaline and mirabegron in the isolated whole rat and guinea pig bladder. Autonomic neuroscience : basic & clinical, 2016, Volume: 198 Topics: Acetanilides; Animals; Arecoline; Carbachol; Female; Guinea Pigs; In Vitro Techniques; Isoproterenol; Muscarinic Agonists; Muscle Contraction; Rats, Sprague-Dawley; Thiazoles; Urinary Bladder	2016
Determination of contents of four alkaloids in Pericarpium arecae by quantitative analysis of multi-components by single-marker. Pakistan journal of pharmaceutical sciences, 2016, Volume: 29, Issue:4 Topics: Alkaloids; Areca; Arecoline; Chromatography, High Pressure Liquid; Limit of Detection; Nicotinic Acids; Reproducibility of Results	2016
Cracking the Betel Nut: Cholinergic Activity of Areca Alkaloids and Related Compounds. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2019, 05-21, Volume: 21, Issue:6 Topics: Alkaloids; Animals; Areca; Arecoline; Behavior, Addictive; Cells, Cultured; Cholinergic Agents; Humans; Nicotinic Acids; Oocytes; Receptors, Muscarinic; Receptors, Nicotinic; Tobacco Use Disorder; Xenopus laevis	2019
Development and validation of a rapid LC-MS/MS method for simultaneous quantification of arecoline and its two active metabolites in rat plasma and its application to a pharmacokinetic study. Journal of pharmaceutical and biomedical analysis, 2018, May-30, Volume: 154 Topics: Animals; Areca; Arecoline; Chromatography, High Pressure Liquid; Cyclic N-Oxides; Limit of Detection; Male; Plasma; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tandem Mass Spectrometry	2018
Development and preliminary validation of a mandarin Chinese language questionnaire measuring betel quid dependency among adults in Taiwan. Psychiatry research, 2019, Volume: 271 Topics: Adult; Areca; Arecoline; Asian People; Cross-Sectional Studies; Factor Analysis, Statistical; Female; Humans; Language; Male; Middle Aged; Odds Ratio; Reproducibility of Results; Substance-Related Disorders; Surveys and Questionnaires; Taiwan; Translations	2019
Tissue-specific and maturity-dependent distribution of pyridine alkaloids in Areca triandra. Journal of plant research, 2019, Volume: 132, Issue:4 Topics: Alkaloids; Areca; Arecoline; Chromatography, High Pressure Liquid; Flowers; Fruit; Mass Spectrometry; Nicotinic Acids; Plant Leaves; Pyridines	2019
Functional Characterization of Muscarinic Receptors in Human Schwann Cells. International journal of molecular sciences, 2020, Sep-11, Volume: 21, Issue:18 Topics: Adult; Alkynes; Arecoline; Cell Differentiation; Cell Proliferation; Cells, Cultured; Ethers; Female; Humans; Middle Aged; Neuroglia; Receptors, Muscarinic; Schwann Cells	2020