arecoline has been researched along with arecaidine in 60 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 6 (10.00) | 18.7374 |
1990's | 8 (13.33) | 18.2507 |
2000's | 22 (36.67) | 29.6817 |
2010's | 22 (36.67) | 24.3611 |
2020's | 2 (3.33) | 2.80 |
Authors | Studies |
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Bellman, K; Knegtel, RM; Settimo, L | 1 |
Brand, SJ; Curtis, DR; Johnston, GA; Lodge, D | 1 |
Bergmeier, SC; Coughenour, LL; Davis, RE; Hershenson, FM; Kester, JA; Marriott, JG; McKee, JS; Moos, WH; Schwarz, RD; Tecle, H | 1 |
Arvidson, K; Bartsch, H; Grafström, RC; Liu, Y; Nair, J; Sundqvist, K | 1 |
Harvey, W; Meghji, S; Scutt, A | 1 |
Panigrahi, GB; Rao, AR | 1 |
Chen, CC; Huang, JF; Tsai, CC | 1 |
Classen, M; Schaffer, K; Schepp, W; Schusdziarra, V; Wegner, U; Weigert, N | 1 |
de Miranda, CM; Grobler-Rabie, AF; Olivier, A; van der Bijl, P; van Wyk, CW | 1 |
Chaudhuri, L; Ganguly, DK | 1 |
Chen, YK; Huang, YL; Lai, DL; Lin, LM | 1 |
Peng, CH; Wang, CK | 1 |
Ma, RH; Shieh, TY; Tsai, CC | 1 |
Ahmed, A; Hengesteg, A; Robbins, KT; Wani, MK; Yarber, RH | 1 |
Stander, IA; Van Eyk, AD; Van Wyk, CW | 1 |
Bernardini, N; Reeh, PW; Sauer, SK | 1 |
van der Bijl, P; van Eyk, AD | 2 |
Drake, MJ; Gillespie, JI; Harvey, IJ | 2 |
NAKAJIMA, H; RUMPF, P; THUILLIER, G; THUILLIER, J | 1 |
CHILTON, J; STENLAKE, JB | 1 |
Dussor, GO; Flores, CM; Hargreaves, KM; Helesic, G | 1 |
Bukharaeva, EA; Magazanik, LG; Nikolsky, EE; Samigullin, D; Vyskocil, F | 1 |
Drake, MJ; Gillespie, JI; Lagou, M | 1 |
Andersson, KE; Drake, MJ; Gillespie, JI; Kirkwood, T; Lagou, M | 1 |
Lai, KC; Lee, TC | 1 |
Chen, C; Giri, S; Gonzalez, FJ; Idle, JR; Krausz, KW; Zabriskie, TM | 1 |
De Ridder, D; Gevaert, T; Ost, D | 1 |
Drake, MJ; Gillespie, J; Harvey, I; Kirkwood, T; Lagou, M | 1 |
Andersson, KE; Drake, M; Gillespie, J; Harvey, I; Hedlund, P; Lagou, M | 1 |
Giri, S; Gonzalez, FJ; Idle, JR; Krausz, KW | 1 |
Finney, SM; Gillespie, JI; Stewart, LH | 2 |
Ikeda, Y; Kanai, A | 1 |
Chang, CK; Cheng, JT; Cheng, KC; Juang, SW; Kou, DH; Liu, IM; Tong, YC | 1 |
Feng, CH; Lu, CY | 1 |
Chang, YZ; Chao, MR; Hu, CW; Wang, HW | 1 |
Coppola, M; Mondola, R | 1 |
Gao, W; Guo, D; Han, J; Liang, Y; Ren, Z; Wang, B; Yang, D; Yuan, J; Zeng, W | 1 |
Calogero, A; Di Bari, M; Fabbiano, C; Ferretti, M; Ponti, D; Tata, AM | 1 |
Khan, I; Kondaiah, P; Kumar, N; Narra, S; Pant, I | 1 |
Chang, MC; Cheng, RH; Hahn, LJ; Ho, YS; Hsien, HC; Jeng, JH; Jeng, PY; Lin, LD; Wang, TM; Wu, HL | 1 |
de Wachter, SG; Rahnama'i, MS; van Kerrebroeck, PE; van Koeveringe, GA | 1 |
Brandsch, M; Laug, L; Markwardt, F; Thondorf, I; Voigt, V; Zebisch, K | 1 |
Calogero, A; Castigli, E; Conte, C; Di Bari, M; Fabbiano, C; Ferretti, M; Ponti, D; Raco, A; Ricordy, R; Ruggieri, P; Sciaccaluga, M; Tata, AM | 1 |
Catacuzzeno, L; De Angelis, F; Fioretti, B; Franciolini, F; Marinelli, S; Pavone, F; Tata, AM | 1 |
Avallone, B; Costantino, M; De Stefano, ME; Loreti, S; Magnaghi, V; Pisano, A; Talora, C; Tata, AM; Uggenti, C | 1 |
Calogero, A; Carbone, A; Coccia, A; De Falco, E; Di Bari, M; Pacini, L; Pastore, AL; Petrozza, V; Ponti, D; Siciliano, C; Tata, AM | 1 |
Lu, TL; Mao, CQ; Mao, SH; Tang, LJ; Wu, H; Yu, HL | 1 |
Ali, S; Atif, M; Hassona, Y; James, EL; Lone, MA; Parkinson, EK; Pitiyage, GN; Prime, SS; Rehman, A | 1 |
Franke, AA; Lai, JF; Li, X | 1 |
De Wachter, S; Eastham, J; Gillespie, J; Persyn, S; Wyndaele, JJ | 1 |
Cai, B; Tang, L; Wang, K; Wu, H; Yin, Y; Yu, H; Zhang, C; Zhang, X | 1 |
Horenstein, NA; Papke, RL; Quadri, M; Shoaib, M; Stokes, C | 1 |
Huang, L; Li, Y; Lu, Y; Pan, H; Shi, F; Zhou, X | 1 |
Chiu, CF; Gritz, ER; Hsu, WY; Lai, CC; Lam, C; Li, CI; Li, TC; Lin, CC; Liu, CS; Lu, IY; Tamí-Maury, I; Tsai, MH | 1 |
Grünhofer, P; Schreiber, L; Wan, Y; Wang, S; Wu, J; Yuan, L; Zhang, H | 1 |
Faroni, A; Piovesana, R; Reid, AJ; Tata, AM | 1 |
Chong, KW; Chua, NQE; Cirillo, N; Dang, S; Davis, A; Prime, SS; Zhang, P | 1 |
2 review(s) available for arecoline and arecaidine
Article | Year |
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Potential action of betel alkaloids on positive and negative symptoms of schizophrenia: a review.
Topics: Alkaloids; Areca; Arecoline; Cholinergic Agents; Humans; Male; Phytotherapy; Schizophrenia; Schizophrenic Psychology | 2012 |
Molecular Mechanisms of Malignant Transformation of Oral Submucous Fibrosis by Different Betel Quid Constituents-Does Fibroblast Senescence Play a Role?
Topics: Areca; Arecoline; Carcinoma, Squamous Cell; Disease Progression; Humans; Mouth Neoplasms; Nicotinic Acids; Oral Submucous Fibrosis; Plant Extracts | 2022 |
58 other study(ies) available for arecoline and arecaidine
Article | Year |
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Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Effects of the Areca nut constituents arecaidine and guvacine on the action of GABA in the cat central nervous system.
Topics: Action Potentials; Alanine; Aminobutyrates; Animals; Areca; Arecoline; Bicuculline; Cats; Cerebellum; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Mice; Neural Inhibition; Nicotinic Acids; Nipecotic Acids; Plant Extracts; Plants, Medicinal; Purkinje Cells; Reflex, Monosynaptic; Seizures; Spinal Cord | 1977 |
Cholinergic agents: effect of methyl substitution in a series of arecoline derivatives on binding to muscarinic acetylcholine receptors.
Topics: Animals; Arecoline; Choline; Dioxolanes; Muscarinic Antagonists; Parasympathomimetics; Quinuclidinyl Benzilate; Rats; Receptors, Muscarinic; Structure-Activity Relationship; Tritium | 1992 |
Cytotoxic and genotoxic effects of areca nut-related compounds in cultured human buccal epithelial cells.
Topics: Arecoline; Colony-Forming Units Assay; DNA Damage; Epithelium; Humans; Mouth Mucosa; Nitroso Compounds | 1989 |
Stimulation of human fibroblast collagen synthesis in vitro by gamma-aminobutyric acid.
Topics: Arecoline; Cell Division; Cells, Cultured; Collagen; Fibroblasts; gamma-Aminobutyric Acid; Humans | 1987 |
Induction of in vivo sister chromatid exchanges by arecaidine, a betel nut alkaloid, in mouse bone-marrow cells.
Topics: Animals; Areca; Arecoline; Bone Marrow; Crossing Over, Genetic; Dose-Response Relationship, Drug; Female; Injections, Intraperitoneal; Male; Mice; Mice, Inbred Strains; Nuts; Plants, Medicinal; Sister Chromatid Exchange; Time Factors | 1984 |
In vitro production of interleukin-6 by human gingival, normal buccal mucosa, and oral submucous fibrosis fibroblasts treated with betel-nut alkaloids.
Topics: Adult; Arecoline; Cells, Cultured; Fibroblasts; Gingiva; Humans; Interleukin-6; Middle Aged; Mouth Mucosa; Oral Submucous Fibrosis; Parasympathomimetics | 1995 |
Functional characterization of a muscarinic receptor stimulating gastrin release from rabbit antral G-cells in primary culture.
Topics: Animals; Arecoline; Atropine; Benzodiazepinones; Carbachol; Cell Adhesion; Cell Separation; Cells, Cultured; Gastrins; Immunohistochemistry; Male; Muscarinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Pyloric Antrum; Rabbits; Receptors, Muscarinic | 1994 |
Observations on the effect of areca nut extracts on oral fibroblast proliferation.
Topics: Areca; Arecoline; Cell Death; Cell Division; Cell Line; Cell Survival; Chromatography, High Pressure Liquid; Cooking; Dose-Response Relationship, Drug; Fibroblasts; Humans; Mouth Mucosa; Plant Extracts; Plants, Medicinal | 1994 |
Involvement of gamma-aminobutyric acid in the stimulatory effect of metoclopramide on gastrointestinal motility.
Topics: Aminobutyrates; Animals; Arecoline; Bicuculline; Drug Interactions; Ethylenediamines; gamma-Aminobutyric Acid; Gastrointestinal Motility; Guinea Pigs; Ileum; Male; Metoclopramide; Muscle Contraction; Myenteric Plexus; Neuromuscular Junction; Neurotransmitter Uptake Inhibitors; Sensitivity and Specificity; Stimulation, Chemical | 1994 |
Minimal arecaidine concentrations showing a promotion effect during DMBA-induced hamster cheek pouch carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Arecoline; Carcinogens; Carcinoma, Squamous Cell; Cheek; Cocarcinogenesis; Cricetinae; Dose-Response Relationship, Drug; Drug Synergism; Leukoplakia, Oral; Male; Mesocricetus; Mouth Neoplasms; Papilloma; Stomatitis | 1996 |
The mutagenicities of alkaloids and N-nitrosoguvacoline from betel quid.
Topics: Alkaloids; Animals; Areca; Arecoline; Carcinogens; Hydrogen-Ion Concentration; Liver; Mutagenicity Tests; Mutagens; Nicotinic Acids; Nitroso Compounds; Phenols; Plant Extracts; Plants, Medicinal; Rats; Salmonella typhimurium; Sodium Nitrite; Taiwan | 1996 |
Deficiency in collagen and fibronectin phagocytosis by human buccal mucosa fibroblasts in vitro as a possible mechanism for oral submucous fibrosis.
Topics: Administration, Topical; Adolescent; Adult; Anti-Inflammatory Agents; Areca; Arecoline; Cells, Cultured; Child; Collagen; Female; Fibroblasts; Fibronectins; Glucocorticoids; Humans; Male; Mouth Mucosa; Oral Submucous Fibrosis; Phagocytosis; Plants, Medicinal; Triamcinolone | 1999 |
Cancer induction in the DMBA hamster cheek pouch: a modified technique using a promoter.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Arecoline; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cheek; Cricetinae; Disease Models, Animal; Mesocricetus; Mouth Mucosa; Mouth Neoplasms; Sutures | 2001 |
Diffusion of reduced arecoline and arecaidine through human vaginal and buccal mucosa.
Topics: Adolescent; Adult; Analysis of Variance; Areca; Arecoline; Cholinergic Agonists; Diffusion; Female; Humans; Male; Middle Aged; Mouth Mucosa; Mucous Membrane; Permeability; Plants, Medicinal; Statistics as Topic; Time Factors; Vagina | 2001 |
Muscarinic M2 receptors inhibit heat-induced CGRP release from isolated rat skin.
Topics: Acetylcholine; Animals; Arecoline; Calcitonin Gene-Related Peptide; Dose-Response Relationship, Drug; Female; Hot Temperature; In Vitro Techniques; Male; Muscarine; Muscarinic Agonists; Nicotine; Nicotinic Agonists; Nociceptors; Rats; Receptor, Muscarinic M2; Receptors, Muscarinic; Skin | 2001 |
Areca nut extract lowers the permeability of vaginal mucosa to reduced arecoline and arecaidine.
Topics: Adult; Aged; Analysis of Variance; Areca; Arecoline; Diffusion Chambers, Culture; Female; Humans; Kinetics; Middle Aged; Mucous Membrane; Permeability; Plant Extracts; Statistics, Nonparametric; Vagina | 2001 |
Autonomous activity in the isolated guinea pig bladder.
Topics: Animals; Arecoline; Atropine; Female; Guinea Pigs; Homeostasis; In Vitro Techniques; Movement; Muscle Contraction; Muscle, Smooth; Pressure; Tetrodotoxin; Urinary Bladder; Urination | 2003 |
Agonist- and nerve-induced phasic activity in the isolated whole bladder of the guinea pig: evidence for two types of bladder activity.
Topics: Anesthetics, Local; Animals; Arecoline; Atropine; Carbachol; Cholinergic Agonists; Electric Stimulation; Female; Guinea Pigs; Hexamethonium; Lobeline; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Nicotinic Agonists; Nicotinic Antagonists; Stimulation, Chemical; Tetrodotoxin; Urinary Bladder | 2003 |
Comparative in vitro permeability of human vaginal, small intestinal and colonic mucosa.
Topics: Adult; Aged; Arecoline; Colon; Diffusion Chambers, Culture; Estradiol; Female; Humans; In Vitro Techniques; Intestinal Mucosa; Intestine, Small; Male; Membranes; Middle Aged; Mouth Mucosa; Mucous Membrane; Permeability; Vagina | 2003 |
[Effect on the central nervous system of simplified structural analogs of LSD 25 derived from arecaidine amides].
Topics: Amides; Anesthetics, Local; Arecoline; Central Nervous System; Lysergic Acid Diethylamide; Niacin; Nicotinic Acids | 1958 |
Dissociation constants of some compounds related to lysergic acid. II. Ergometrine, ergometrinine and alkanolamides of 3-dimethylaminopropionic acid, 1-methylhexahydronicotinic acid and arecaidine.
Topics: Arecoline; Cardiovascular Agents; Ergonovine; Ergot Alkaloids; Lysergic Acid | 1962 |
Cholinergic modulation of nociceptive responses in vivo and neuropeptide release in vitro at the level of the primary sensory neuron.
Topics: Acetylcholine; Analysis of Variance; Animals; Arecoline; Atropine; Behavior, Animal; Bungarotoxins; Calcitonin Gene-Related Peptide; Capsaicin; Cell Count; Disinfectants; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Formaldehyde; Gallamine Triethiodide; Gene Expression Regulation; Grooming; In Situ Hybridization; In Vitro Techniques; Male; Mecamylamine; Mouth Mucosa; Muscarinic Antagonists; Neurons, Afferent; Nicotinic Antagonists; Pain; Pain Measurement; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptors, Drug; RNA, Messenger; Time; Trigeminal Ganglion | 2004 |
Cholinergic regulation of the evoked quantal release at frog neuromuscular junction.
Topics: Acetylcholine; Action Potentials; Animals; Arecoline; Carbachol; Cholinergic Agonists; Diamines; Motor Neurons; Muscarinic Agonists; Muscarinic Antagonists; Neural Conduction; Neuromuscular Junction; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Oxotremorine; Parasympatholytics; Pirenzepine; Rana ridibunda; Receptors, Muscarinic; Synaptic Transmission; Tubocurarine | 2004 |
Volume-induced effects on the isolated bladder: a possible local reflex.
Topics: Animals; Arecoline; Autonomic Nervous System; Carbachol; Electrophysiology; Female; Guinea Pigs; In Vitro Techniques; Muscarinic Agonists; Pressure; Reflex, Stretch; Tetrodotoxin; Urinary Bladder; Vesico-Ureteral Reflux | 2004 |
Bladder volume alters cholinergic responses of the isolated whole mouse bladder.
Topics: Animals; Arecoline; Female; In Vitro Techniques; Mice; Mice, Inbred C57BL; Muscarinic Agonists; Urinary Bladder | 2006 |
Genetic damage in cultured human keratinocytes stressed by long-term exposure to areca nut extracts.
Topics: Apoptosis; Areca; Arecoline; Cell Line; Cell Proliferation; DNA Damage; Glutathione; Guanosine; Humans; Hypoxanthine Phosphoribosyltransferase; Keratinocytes; Micronucleus Tests; Mutation; Plant Extracts; Reactive Oxygen Species | 2006 |
A metabolomic approach to the metabolism of the areca nut alkaloids arecoline and arecaidine in the mouse.
Topics: Animals; Areca; Arecoline; Gas Chromatography-Mass Spectrometry; Male; Mice; Molecular Structure | 2006 |
Comparison study of autonomous activity in bladders from normal and paraplegic rats.
Topics: Animals; Arecoline; Carbachol; Cholinergic Agonists; Female; Muscarinic Agonists; Muscle Contraction; Paraplegia; Pressure; Rats; Rats, Wistar; Urinary Bladder; Urinary Bladder, Neurogenic; Urodynamics | 2006 |
Muscarinic stimulation of the mouse isolated whole bladder: physiological responses in young and ageing mice.
Topics: Age Factors; Aging; Animals; Arecoline; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Mice; Mice, Inbred C57BL; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Physostigmine; Receptors, Muscarinic; Urinary Bladder; Urination Disorders | 2006 |
Muscarinic stimulation of the rat isolated whole bladder: pathophysiological models of detrusor overactivity.
Topics: Animals; Arecoline; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hypertension; Male; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Rats, Wistar; Urinary Bladder; Urinary Bladder Neck Obstruction | 2006 |
The metabolomics of (+/-)-arecoline 1-oxide in the mouse and its formation by human flavin-containing monooxygenases.
Topics: Acetylcysteine; Administration, Oral; Animals; Arecoline; Chromatography, Liquid; Cyclic N-Oxides; Cytochrome P-450 Enzyme System; Dogs; Humans; Kinetics; Male; Mass Spectrometry; Metabolic Networks and Pathways; Mice; Molecular Structure; Nipecotic Acids; Oxygenases; Piperidines; Recombinant Proteins; Stereoisomerism; Sulfhydryl Compounds; Urinalysis | 2007 |
Cholinergic activation of phasic activity in the isolated bladder: possible evidence for M3- and M2-dependent components of a motor/sensory system.
Topics: Animals; Arecoline; Benzofurans; Carbachol; Cholinergic Agonists; Female; Guinea Pigs; Muscarinic Agonists; Piperidines; Pyrrolidines; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Urinary Bladder; Urination | 2007 |
Urotheliogenic modulation of intrinsic activity in spinal cord-transected rat bladders: role of mucosal muscarinic receptors.
Topics: Animals; Arecoline; Calcium Channel Blockers; Disease Models, Animal; Female; Mucous Membrane; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Nifedipine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Spinal Cord; Urinary Bladder; Urinary Bladder, Overactive; Urothelium | 2008 |
Role of hyperglycaemia in the pathogenesis of hypotension observed in type-1 diabetic rats.
Topics: Animals; Arecoline; Baroreflex; Cell Line; Cholinergic Agonists; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Gene Expression; Glucose; Hyperglycemia; Hypotension; Insulin; Male; Phenylephrine; Phlorhizin; Rats; Rats, Wistar; Receptor, Muscarinic M2; RNA, Messenger | 2008 |
Volume-induced responses in the isolated bladder: evidence for excitatory and inhibitory elements.
Topics: Animals; Arecoline; Autonomic Nervous System; Female; Guinea Pigs; Urinary Bladder | 2008 |
A new matrix for analyzing low molecular mass compounds and its application for determination of carcinogenic areca alkaloids by matrix-assisted laser desorption ionization time-of-flight mass spectrometry.
Topics: Arecoline; Carcinogens; Humans; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2009 |
High-throughput simultaneous analysis of five urinary metabolites of areca nut and tobacco alkaloids by isotope-dilution liquid chromatography-tandem mass spectrometry with on-line solid-phase extraction.
Topics: Adult; Areca; Arecoline; Chromatography, High Pressure Liquid; Cotinine; Cross-Sectional Studies; Humans; Male; Middle Aged; Nicotiana; Nicotine; Smoking; Solid Phase Extraction; Tandem Mass Spectrometry; Young Adult | 2010 |
Alkaloids from areca (betel) nuts and their effects on human sperm motility in vitro.
Topics: Adult; Alkaloids; Areca; Arecoline; China; Chromatography, High Pressure Liquid; Food, Preserved; Humans; Image Processing, Computer-Assisted; Infertility, Male; Male; Nicotinic Acids; Nuts; Osmolar Concentration; Plant Epidermis; Semen Analysis; Sperm Motility; Spermatozoa; Young Adult | 2012 |
M2 muscarinic receptors inhibit cell proliferation in human glioblastoma cell lines.
Topics: Arecoline; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Receptor, Muscarinic M2; Reverse Transcriptase Polymerase Chain Reaction | 2012 |
Activation of TGF-β pathway by areca nut constituents: a possible cause of oral submucous fibrosis.
Topics: Areca; Arecoline; Biomarkers; Cells, Cultured; Collagen; Fibroblasts; Gene Expression Profiling; Gingiva; Humans; Keratinocytes; Mastication; Nuts; Oligonucleotide Array Sequence Analysis; Oral Submucous Fibrosis; Phosphorylation; Plant Extracts; Plants, Toxic; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Smad2 Protein; Transforming Growth Factor beta; Up-Regulation | 2012 |
Areca nut-induced buccal mucosa fibroblast contraction and its signaling: a potential role in oral submucous fibrosis--a precancer condition.
Topics: Areca; Arecoline; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cells, Cultured; Fibroblasts; Humans; Inositol 1,4,5-Trisphosphate Receptors; Mouth Mucosa; Mouth Neoplasms; Myosin Light Chains; Nuts; Oral Submucous Fibrosis; Phosphorylation; Plant Extracts; Precancerous Conditions; Reactive Oxygen Species; Signal Transduction | 2013 |
The effect of indomethacin on the muscarinic induced contractions in the isolated normal guinea pig urinary bladder.
Topics: Animals; Arecoline; Cyclooxygenase Inhibitors; Dinoprostone; Guinea Pigs; Indomethacin; Male; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Urinary Bladder | 2013 |
Transport of the areca nut alkaloid arecaidine by the human proton-coupled amino acid transporter 1 (hPAT1).
Topics: Amino Acid Transport Systems; Animals; Areca; Arecoline; Binding, Competitive; Biological Transport; Caco-2 Cells; Drugs, Investigational; Enterocytes; Female; GABA Agonists; GABA Uptake Inhibitors; HeLa Cells; Humans; Intestinal Absorption; Isonicotinic Acids; Kinetics; Nicotinic Acids; Nuts; Oocytes; Recombinant Proteins; Symporters; Xenopus laevis | 2013 |
M2 receptor activation inhibits cell cycle progression and survival in human glioblastoma cells.
Topics: Antineoplastic Agents; Apoptosis; Arecoline; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Glioblastoma; Humans; Inhibitory Concentration 50; Muscarinic Agonists; Muscarinic Antagonists; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Receptor, Muscarinic M2; Signal Transduction | 2013 |
M2 receptors exert analgesic action on DRG sensory neurons by negatively modulating VR1 activity.
Topics: Animals; Arecoline; Cells, Cultured; Cholinergic Agonists; Gene Expression Regulation; Hyperalgesia; Injections, Intraperitoneal; Male; Mice; Mice, Knockout; Nerve Growth Factor; Patch-Clamp Techniques; Protein Kinase C-epsilon; Rats; Rats, Wistar; Receptor, Muscarinic M2; Sensory Receptor Cells; TRPV Cation Channels | 2014 |
M2 muscarinic receptor activation regulates Schwann cell differentiation and myelin organization.
Topics: Animals; Arecoline; Axons; Cells, Cultured; Mice, Knockout; Myelin Proteins; Myelin Sheath; Nerve Degeneration; Neurogenesis; Peripheral Nervous System Agents; Rats, Wistar; Receptor, Muscarinic M2; Receptor, Muscarinic M4; RNA, Messenger; Schwann Cells; Sciatic Nerve; Signal Transduction; Transcription Factors | 2014 |
M2muscarinic receptors inhibit cell proliferation and migration in urothelial bladder cancer cells.
Topics: Arecoline; Biopsy; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Gene Expression; Humans; Muscarinic Antagonists; Neoplasm Grading; Receptor, Muscarinic M2; Urinary Bladder Neoplasms | 2014 |
[Optimization of Preparation of Cutting-processed Arecae Pericarpium with Multi-index Orthogonal Method].
Topics: Alkaloids; Areca; Arecoline; Drugs, Chinese Herbal; Nicotinic Acids | 2014 |
Areca nut alkaloids induce irreparable DNA damage and senescence in fibroblasts and may create a favourable environment for tumour progression.
Topics: Areca; Arecoline; beta-Galactosidase; Cell Cycle; Cell Line; Cellular Senescence; Disease Progression; DNA Damage; Fibroblasts; Humans; Matrix Metalloproteinase 2; Mouth Neoplasms; Oral Submucous Fibrosis; Transforming Growth Factor beta; Tumor Suppressor p53-Binding Protein 1 | 2016 |
Pilot study of the pharmacokinetics of betel nut and betel quid biomarkers in saliva, urine, and hair of betel consumers.
Topics: Alkaloids; Areca; Arecoline; Biomarkers; Body Fluids; Hair; Humans; Mass Spectrometry; Nicotinic Acids; Pilot Projects; Saliva | 2016 |
The actions of isoprenaline and mirabegron in the isolated whole rat and guinea pig bladder.
Topics: Acetanilides; Animals; Arecoline; Carbachol; Female; Guinea Pigs; In Vitro Techniques; Isoproterenol; Muscarinic Agonists; Muscle Contraction; Rats, Sprague-Dawley; Thiazoles; Urinary Bladder | 2016 |
Determination of contents of four alkaloids in Pericarpium arecae by quantitative analysis of multi-components by single-marker.
Topics: Alkaloids; Areca; Arecoline; Chromatography, High Pressure Liquid; Limit of Detection; Nicotinic Acids; Reproducibility of Results | 2016 |
Cracking the Betel Nut: Cholinergic Activity of Areca Alkaloids and Related Compounds.
Topics: Alkaloids; Animals; Areca; Arecoline; Behavior, Addictive; Cells, Cultured; Cholinergic Agents; Humans; Nicotinic Acids; Oocytes; Receptors, Muscarinic; Receptors, Nicotinic; Tobacco Use Disorder; Xenopus laevis | 2019 |
Development and validation of a rapid LC-MS/MS method for simultaneous quantification of arecoline and its two active metabolites in rat plasma and its application to a pharmacokinetic study.
Topics: Animals; Areca; Arecoline; Chromatography, High Pressure Liquid; Cyclic N-Oxides; Limit of Detection; Male; Plasma; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tandem Mass Spectrometry | 2018 |
Development and preliminary validation of a mandarin Chinese language questionnaire measuring betel quid dependency among adults in Taiwan.
Topics: Adult; Areca; Arecoline; Asian People; Cross-Sectional Studies; Factor Analysis, Statistical; Female; Humans; Language; Male; Middle Aged; Odds Ratio; Reproducibility of Results; Substance-Related Disorders; Surveys and Questionnaires; Taiwan; Translations | 2019 |
Tissue-specific and maturity-dependent distribution of pyridine alkaloids in Areca triandra.
Topics: Alkaloids; Areca; Arecoline; Chromatography, High Pressure Liquid; Flowers; Fruit; Mass Spectrometry; Nicotinic Acids; Plant Leaves; Pyridines | 2019 |
Functional Characterization of Muscarinic Receptors in Human Schwann Cells.
Topics: Adult; Alkynes; Arecoline; Cell Differentiation; Cell Proliferation; Cells, Cultured; Ethers; Female; Humans; Middle Aged; Neuroglia; Receptors, Muscarinic; Schwann Cells | 2020 |