arecoline has been researched along with 2-ethyl-8-methyl-2,8-diazaspiro(4,5)decane-1,3-dione in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 5 (71.43) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baker, R; Book, T; Freedman, SB; Herbert, RH; Kneen, CO; MacLeod, AM; Merchant, KJ; Saunders, J; Showell, GA; Street, LJ | 1 |
| Baker, R; Cassidy, M; Freedman, SB; Harley, EA; Iversen, LL; Kneen, C; MacLeod, AM; Merchant, KJ; Saunders, J; Snow, RJ | 1 |
| Baker, R; Freedman, SB; Harley, EA; Saunders, J; Showell, GA; Snow, RJ | 1 |
| Bøgesø, KP; Frederiksen, K; Løve Lembøl, H; Meier, E; Moltzen, EK; Pedersen, H; Sánchez, C | 1 |
| Bromidge, SM; Brown, F; Cassidy, F; Clark, MS; Dabbs, S; Hadley, MS; Hawkins, J; Loudon, JM; Naylor, CB; Orlek, BS; Riley, GJ | 1 |
| Bemis, KG; Hendrix, JC; Shannon, HE; Ward, JS | 1 |
| Davis, KL; Hollander, E; Mohs, RC | 1 |
1 review(s) available for arecoline and 2-ethyl-8-methyl-2,8-diazaspiro(4,5)decane-1,3-dione
| Article | Year |
|---|---|
Cholinergic approaches to the treatment of Alzheimer's disease.
Topics: 4-Aminopyridine; Alanine; Alzheimer Disease; Aminopyridines; Arecoline; Clinical Trials as Topic; Humans; Parasympathomimetics; Physostigmine; Piracetam; Pyrrolidines; Research Design; Succinimides; Synapses | 1986 |
1 trial(s) available for arecoline and 2-ethyl-8-methyl-2,8-diazaspiro(4,5)decane-1,3-dione
| Article | Year |
|---|---|
Cholinergic approaches to the treatment of Alzheimer's disease.
Topics: 4-Aminopyridine; Alanine; Alzheimer Disease; Aminopyridines; Arecoline; Clinical Trials as Topic; Humans; Parasympathomimetics; Physostigmine; Piracetam; Pyrrolidines; Research Design; Succinimides; Synapses | 1986 |
6 other study(ies) available for arecoline and 2-ethyl-8-methyl-2,8-diazaspiro(4,5)decane-1,3-dione
| Article | Year |
|---|---|
Synthesis and biological activity of 1,2,4-oxadiazole derivatives: highly potent and efficacious agonists for cortical muscarinic receptors.
Topics: Animals; Cerebral Cortex; In Vitro Techniques; Ligands; Oxadiazoles; Parasympathomimetics; Rats; Receptors, Muscarinic; Receptors, Nicotinic; Stereoisomerism; Structure-Activity Relationship | 1990 |
Novel quinuclidine-based ligands for the muscarinic cholinergic receptor.
Topics: Animals; Binding Sites; Cerebral Cortex; Computer Simulation; Kinetics; Models, Chemical; Oxadiazoles; Quinuclidines; Rats; Receptors, Muscarinic; Structure-Activity Relationship | 1990 |
2-Methyl-1,3-dioxaazaspiro[4.5]decanes as novel muscarinic cholinergic agonists.
Topics: Animals; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Dioxolanes; Dioxoles; In Vitro Techniques; Inositol Phosphates; Male; Molecular Conformation; N-Methylscopolamine; Oxotremorine; Parasympathomimetics; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Spiro Compounds; Structure-Activity Relationship | 1988 |
Bioisosteres of arecoline: 1,2,3,6-tetrahydro-5-pyridyl-substituted and 3-piperidyl-substituted derivatives of tetrazoles and 1,2,3-triazoles. Synthesis and muscarinic activity.
Topics: Animals; Arecoline; Female; Guinea Pigs; Male; Mice; Rats; Rats, Wistar; Structure-Activity Relationship; Tetrazoles; Triazoles | 1994 |
Design of [R-(Z)]-(+)-alpha-(methoxyimino)-1-azabicyclo[2.2.2]octane-3-acetonitri le (SB 202026), a functionally selective azabicyclic muscarinic M1 agonist incorporating the N-methoxy imidoyl nitrile group as a novel ester bioisostere.
Topics: Alzheimer Disease; Animals; Binding Sites; Blood Pressure; Brain; CHO Cells; Cricetinae; Electroencephalography; Heart Rate; Humans; Imines; Magnetic Resonance Spectroscopy; Male; Models, Molecular; Molecular Structure; Muscarinic Agonists; Protein Binding; Quinuclidines; Rats; Rats, Inbred Strains; Receptor, Muscarinic M1; Receptors, Muscarinic; Recombinant Proteins; Stereoisomerism; Tremor | 1997 |
Interactions between scopolamine and muscarinic cholinergic agonists or cholinesterase inhibitors on spatial alternation performance in rats.
Topics: Animals; Arecoline; Behavior, Animal; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Male; Memory; Oxotremorine; Parasympathomimetics; Physostigmine; Pilocarpine; Rats; Rats, Inbred F344; Scopolamine; Spatial Behavior; Succinimides; Tacrine | 1990 |