arctiin has been researched along with glucose, (beta-d)-isomer in 76 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.32) | 18.7374 |
| 1990's | 3 (3.95) | 18.2507 |
| 2000's | 23 (30.26) | 29.6817 |
| 2010's | 37 (48.68) | 24.3611 |
| 2020's | 12 (15.79) | 2.80 |
| Authors | Studies |
|---|---|
| Fujimoto, T; Nishibe, S; Nose, M; Ogihara, Y; Takeda, T | 1 |
| Gao, H; Sha, ZF; Sun, WJ | 1 |
| Fujimoto, T; Nishibe, S; Nose, M; Ogihara, Y | 1 |
| Futakuchi, M; Hirose, M; Kimoto, N; Kono, T; Lin, C; Nishibe, S; Shirai, T; Yamaguchi, T | 1 |
| Delle Monache, F; Menichini, F; Statti, G; Tundis, R | 1 |
| Abdel-Hafez, AA; Ahn, EM; Akao, T; Hattori, M; Nakamura, N; Xie, LH | 1 |
| Xin, Q; Xiong, J; Yan, XP; Yu, BS | 1 |
| HAENSEL, R; LEUCKERT, C; SCHULZ, H | 1 |
| Du, LJ; Liu, B; Lu, YR; Shi, RB; Shi, Y | 1 |
| Chueh, SC; Guh, JH; Huang, DM; Teng, CM | 1 |
| Chen, YP; Wang, HY | 1 |
| Cho, SH; Choi, SW; Choi, Y; Rhee, SJ | 1 |
| Jiang, T; Li, F; Sun, Q; Wang, X; Yuan, J; Zheng, C | 1 |
| Hosokawa, K; Ikeda, M; Imaida, K; Li, JQ; Matsuda, Y; Saoo, K; Takeuchi, H; Yamakawa, K; Yokohira, M; Zeng, Y | 1 |
| Chui, WK; Koh, HL; Yuan, X | 1 |
| Cai, SX; Fu, SQ; Xu, XY; Zheng, YM | 1 |
| Dong, WH; Liu, B | 1 |
| Choi, WS; Ha, CG; Her, E; Jun, SH; Kim, BK; Kim, NW; Kim, YM; Ko, NY; Lee, JH; Lee, JM; Lee, MH; Lee, SH; Mun, SH; Park, SH | 1 |
| Shi, RB; Shi, Y | 1 |
| Hasumura, M; Hirose, M; Imai, T; Onose, J; Ueda, M | 1 |
| Chen, H; Chen, Y; Ding, X; Liu, M; Lü, W; Zhang, Y | 1 |
| Germain, D; Hitomi, T; Kawanaka, M; Koyama, M; Matsuzaki, Y; Nishikawa, A; Sakai, T; Yokota, T | 1 |
| Ahn, KS; Jun, SH; Kang, H; Kim, SN; Lee, JM; Lee, SH; Park, JH; You, JH | 1 |
| Ferracane, R; Fogliano, V; Gallo, M; Graziani, G; Ritieni, A | 1 |
| Du, J; Han, T; Sun, LN; Wu, JG; Wu, JZ; Ye, Q; Zhang, H; Zhang, YG | 1 |
| Hattori, M; Jin, JS | 1 |
| Hayashi, K; Hayashi, T; Nagaoka, Y; Narutaki, K; Uesato, S | 1 |
| Guo, M; Liang, J; Wu, S | 1 |
| Liu, H; Sun, S; Sun, Y; Wang, X; Wang, Y; Yu, A; Zhai, Y; Zhang, H; Zhang, Y | 1 |
| Joh, EH; Kim, DH; Lee, IA | 1 |
| Dou, D; Kang, T; Wang, B; Xu, L; Yang, Y | 1 |
| Du, QS; Guo, TT; Hua, J; Liu, RZ; Tang, X; Yang, L; Zhang, J | 1 |
| De-Qiang, D; Dou, DQ; Fan, H; He, F; Hong-Bin, X; Kang, TG; Lin, Z; Sun, Y; Ting-Guo, K; Xiao, HB; Yu, S; Zhu, L | 1 |
| Li, CW; Li, ZH; Lu, LC; Luo, MH; Xie, H; Yu, CP; Zhou, W | 1 |
| Deng, JJ; Liu, DL; Liu, RB; Ma, ST; Niu, R | 1 |
| Dou, DQ; Han, XY; He, F; Kang, TG; Pan, Q; Tan, RQ; Wang, J; Wang, W | 1 |
| Cai, SQ; Chen, HB; Shang, MY; Wang, RF; Wang, TM | 1 |
| Dou, DQ; Han, XY; Tan, RQ; Wang, W | 1 |
| Lu, LC; Qian, GS; Song, MB; Zhang, R; Zhou, SW | 1 |
| Ahn, KJ; An, IS; An, S; Bae, S; Cha, HJ; Hong, JT; Lee, GT; Lee, KK; Lee, KS | 1 |
| Ahn, KJ; An, IS; An, S; Bae, S; Cha, HJ; Hahn, HJ; Hong, JT; Kim, SY; Lee, BM; Lee, GT; Lee, KK; Lee, KS; Lee, NK; Lee, SJ | 1 |
| Bian, D; Dai, Y; Dou, Y; Kong, L; Tong, B; Wei, Z; Wu, X; Xia, Y; Yang, Y; Ye, J | 1 |
| Ahn, KJ; An, IS; An, S; Bae, S; Cha, HJ; Jung, HJ; Lee, GT; Lee, JP; Lee, KK; Lee, KS; Lim, KM | 1 |
| Bai, G; Cheng, B; Fang, R; Hou, W; Hou, Y; Jiang, M; Zhou, M | 1 |
| Cheng, X; Su, S; Wink, M | 1 |
| Cai, BC; Cai, H; Liu, QD; Qin, KM; Shen, BJ | 1 |
| Hu, SQ; Jiang, XB; Liu, SY; Sun, JY; Wang, T; Zhang, L | 1 |
| Lü, H; Shan, H; Song, J; Sun, Z | 1 |
| Bian, BL; Han, JY; Li, CY; Li, GQ; Liang, AH; Lu, YT; Si, N; Wang, HJ; Xiao, HB; Yi, Y; Zhang, YS; Zhao, HY; Zhao, Y | 1 |
| Cui, X; Fang, ZZ; Wang, T; Wang, Y; Zhang, H; Zhao, Z | 1 |
| Duan, N; Guo, TT; Huang, LL; Liang, XJ; Shu, SS; Tang, X; Wang, Y; Xiang, XH; Yang, L; Zhang, J | 1 |
| Guo, X; Wang, D; Wang, Y; Wu, S; Zhang, L | 1 |
| Hao, QH; Liu, MY; Wang, DM; Wang, XL; Wang, Y; Yu, F; Zhao, YK | 1 |
| Ahn, KJ; An, IS; An, S; Cha, HJ; Choi, BG; Choi, YM; Joo, D; Kim, K | 1 |
| Li, J; Ren, J; Tang, QZ; Wan, CX; Xu, CR; Xu, SC; Yuan, YP; Zeng, XF; Zhang, N | 1 |
| Gao, Q; Yang, M; Zuo, Z | 1 |
| Dai, F; Huang, Z; Liu, T; Weng, G; Zhou, B | 1 |
| Ahn, KS; Kim, C; Lee, J; Lee, JH; Sethi, G; Um, JY | 1 |
| Dong, Z; Hu, J; Qin, K; Shi, Y; Si, X; Yang, B | 1 |
| Chen, H; Li, NS; Luo, XJ; Peng, J; Tang, LJ; Tu, H; Zhou, YJ | 1 |
| Li, G; Lu, L; Zhou, H; Zhou, M; Zhu, L | 1 |
| Chen, D; Chen, P; He, J; Kenny, J; Kuek, V; Liu, Y; Qiu, H; Wang, C; Wang, G; Wang, H; Wang, J; Wang, Q; Wang, Z; Xu, J; Yang, F; Ye, Z; Yuan, J; Zhang, G; Zhang, M | 1 |
| Cheng, JH; Cui, YX; Jin, X; Li, YB; Ma, J; Piao, HN; Piao, LX; Xu, GH; Xu, X; Zeng, XY; Zhao, XD | 1 |
| Cui, SS; Li, M; Li, RM; Li, ZT; Wang, GH; Yuan, YL; Zhang, FX | 1 |
| Lu, X; Qin, G; Wang, G; Xia, L; Yao, W; Zhou, Y | 1 |
| Han, J; Wang, G; Xia, L; Yao, W; Zhou, Y | 1 |
| Li, J; Liang, Y; Pan, X; Wang, L; Zhou, B | 1 |
| Chen, J; He, X; Peng, F; Song, Z; Xiao, J; Yi, J; Zhang, H | 1 |
| Liu, Z; Wu, Y | 1 |
| Chen, X; He, F; Hou, M; Liu, T; Liu, Y; Pan, Z; Shi, Q; Tian, X; Yang, H; Zhang, Y; Zhao, Z; Zhu, X | 1 |
| Guo, K; Huang, X; Liu, S; Wang, X; Xie, J; Xu, X; Zheng, Y | 1 |
| Alföldi, J; Ebringerová, A; Franová, S; Hríbalová, V; Kardosová, A; Nosál'ová, G | 1 |
| Ahn, B; Chung, D; Han, SB; Hong, SS; Hwang, BY; Kim, BH; Kim, Y; Kwon, SW; Lee, CK; Lee, HY; Lee, IJ; Nam, SY; Song, S; Sung, H | 1 |
| Cai, ZZ; Ding, Y; Tao, JS; Yang, YS; Zhang, LY; Zhang, T | 1 |
| Feng, ZM; Huang, XY; Jiang, JS; Yang, YN; Zhang, PC | 2 |
1 review(s) available for arctiin and glucose, (beta-d)-isomer
| Article | Year |
|---|---|
Overview of the anti-inflammatory effects, pharmacokinetic properties and clinical efficacies of arctigenin and arctiin from Arctium lappa L.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Arctium; Cell Line, Tumor; Diabetic Nephropathies; Furans; Glucosides; Humans; Lignans; Neuroprotective Agents; Pancreatic Neoplasms | 2018 |
2 trial(s) available for arctiin and glucose, (beta-d)-isomer
| Article | Year |
|---|---|
[Clinical observation on treatment of diabetic nephropathy with compound fructus arctii mixture].
Topics: Adult; Albuminuria; Astragalus propinquus; Diabetic Nephropathies; Drug Therapy, Combination; Drugs, Chinese Herbal; Female; Furans; Glucosides; Humans; Losartan; Male; Middle Aged; Phytotherapy | 2004 |
Protective effect and possible mechanism of arctiin on broilers challenged by Salmonella pullorum.
Topics: Animal Feed; Animals; Chickens; Diet; Dietary Supplements; Furans; Glucosides; Poultry Diseases; Salmonella | 2022 |
73 other study(ies) available for arctiin and glucose, (beta-d)-isomer
| Article | Year |
|---|---|
Structural transformation of lignan compounds in rat gastrointestinal tract.
Topics: 4-Butyrolactone; Animals; Biotransformation; Furans; Glucosides; Lignans; Lignin; Male; Plants, Medicinal; Rats; Rats, Wistar | 1992 |
Determination of arctiin and arctigenin in Fructus Arctii by reverse-phase HPLC.
Topics: Benzyl Compounds; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Furans; Glucosides; Lignans | 1992 |
Structural transformation of lignan compounds in rat gastrointestinal tract; II. Serum concentration of lignans and their metabolites.
Topics: 4-Butyrolactone; Animals; Digestive System; Drugs, Chinese Herbal; Furans; Glucosides; Lignans; Lignin; Male; Molecular Structure; Rats; Rats, Wistar | 1993 |
Effects of arctiin on PhIP-induced mammary, colon and pancreatic carcinogenesis in female Sprague-Dawley rats and MeIQx-induced hepatocarcinogenesis in male F344 rats.
Topics: Animals; Biological Assay; Body Weight; Carcinogens; Carcinoma; Colonic Neoplasms; Diet; Drugs, Chinese Herbal; Female; Fibroadenoma; Furans; Glucosides; Glutathione Transferase; Imidazoles; Liver; Male; Mammary Neoplasms, Experimental; Pancreatic Neoplasms; Quinoxalines; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Time Factors | 2000 |
Arctiin and onopordopicrin from Carduus micropterus ssp. perspinosus.
Topics: Asteraceae; Furans; Glucosides; Humans; Lactones; Magnetic Resonance Spectroscopy; Plant Structures; Plants, Medicinal; Sesquiterpenes | 2000 |
Transformation of arctiin to estrogenic and antiestrogenic substances by human intestinal bacteria.
Topics: Animals; Bacteria; Biotransformation; Estrogen Receptor Modulators; Estrogens; Feces; Furans; Glucosides; Humans; Intestinal Mucosa; Intestines; Male; Peptostreptococcus; Rats; Rats, Wistar; Tumor Cells, Cultured | 2003 |
Simultaneous determination of chlorogenic acid, forsythin and arctiin in Chinese traditional medicines preparation by reversed phase-HPLC.
Topics: Bridged Bicyclo Compounds, Heterocyclic; Chlorogenic Acid; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Forsythia; Furans; Glucosides | 2003 |
[THE LIGNANE GLYCOSIDE ARCTIIN AS A CHEMOTAXONOMIC CHARACTERISTIC IN THE COMPOSITAE FAMILY].
Topics: Asteraceae; Cardiac Glycosides; Furans; Glucosides; Glycosides; Plants; Research | 1964 |
[Isolation and elucidation of chemical constituents with antiviral action from yinqiaosan on influenza virus].
Topics: Antiviral Agents; Arctium; Drug Combinations; Drugs, Chinese Herbal; Forsythia; Furans; Genistein; Glucosides; Glycosides; Isoflavones; Plants, Medicinal | 2003 |
Modulation of anti-adhesion molecule MUC-1 is associated with arctiin-induced growth inhibition in PC-3 cells.
Topics: Cell Adhesion; Drugs, Chinese Herbal; Flow Cytometry; Furans; Gene Expression Regulation, Neoplastic; Glucosides; Humans; Kinetics; Male; Mucin-1; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Up-Regulation | 2004 |
Effects of forsythia fruit extracts and lignan on lipid metabolism.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Body Weight; Cell Line, Tumor; Cholesterol, Dietary; Dietary Supplements; Forsythia; Furans; Glucosides; Humans; Lignans; Lipid Metabolism; Lipids; Male; Plant Extracts; Rats; Rats, Sprague-Dawley; Seeds | 2004 |
Application of preparative high-speed counter-current chromatography for separation and purification of arctiin from Fructus Arctii.
Topics: Arctium; Chromatography, High Pressure Liquid; Countercurrent Distribution; Furans; Glucosides | 2005 |
Lack of significant modifying effect of arctiin on prostate carcinogenesis in probasin/SV40 T antigen transgenic rats.
Topics: Adenoma; Administration, Oral; Androgen-Binding Protein; Animal Feed; Animals; Animals, Genetically Modified; Antigens, Polyomavirus Transforming; Cell Transformation, Neoplastic; Drugs, Chinese Herbal; Furans; Glucosides; Male; Prostatic Neoplasms; Random Allocation; Rats; Seeds | 2005 |
A high performance liquid chromatography method for the simultaneous determination of arctiin, chlorogenic acid and glycyrrhizin in a Chinese proprietary medicine.
Topics: Acetic Acid; Acetonitriles; Biomarkers; Chemistry, Pharmaceutical; Chlorogenic Acid; Chromatography, High Pressure Liquid; Chromatography, Liquid; Drug Industry; Furans; Glucosides; Glycyrrhizic Acid; Medicine, Chinese Traditional; Models, Chemical; Sensitivity and Specificity; Time Factors; Ultraviolet Rays | 2005 |
[Dyuamical studies on metabolic chemistry of lignans from seeds of Arctium lappa].
Topics: Animals; Arctium; Chromatography, High Pressure Liquid; Furans; Glucosides; Lignans; Liver; Male; Mice; Plants, Medicinal; Reproducibility of Results; Seeds; Tissue Distribution | 2005 |
[Study on condition for extraction of arctiin from fruits of Arctium lappa using supercritical fluid extraction].
Topics: Arctium; Chromatography, High Pressure Liquid; Chromatography, Supercritical Fluid; Fruit; Furans; Glucosides; Plants, Medicinal | 2006 |
In-vitro and in-vivo anti-inflammatory action of the ethanol extract of Trachelospermi caulis.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Carrageenan; Cell Line; Edema; Ethanol; Furans; Glucosides; Male; Mice; Mice, Inbred ICR; Nitric Oxide; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Pain; Plant Extracts; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2007 |
[Relative adscriptions of components in the effective fractions of Yinqiao decoction and its composing individual herbs].
Topics: Arctium; Chlorogenic Acid; Chromatography, High Pressure Liquid; Drug Combinations; Drugs, Chinese Herbal; Flavanones; Forsythia; Furans; Glucosides; Glycosides; Glycyrrhiza uralensis; Lonicera; Plants, Medicinal; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization | 2007 |
Lack of a significant effect of arctiin on development of 7,12-dimethylbenz(a)anthracene-induced mammary tumors in ovariectomized Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Cell Transformation, Neoplastic; Disease Progression; Dose-Response Relationship, Drug; Female; Furans; Glucosides; Incidence; Mammary Neoplasms, Experimental; Ovariectomy; Random Allocation; Rats; Rats, Sprague-Dawley | 2007 |
Microemulsion electrokinetic chromatography for the separation of arctiin and arctigenin in Fructus Arctii and its herbal preparations.
Topics: Arctium; Borates; Chromatography, Micellar Electrokinetic Capillary; Drugs, Chinese Herbal; Emulsions; Furans; Glucosides; Hydrogen-Ion Concentration; Lignans; Reproducibility of Results | 2007 |
Arctiin induces cell growth inhibition through the down-regulation of cyclin D1 expression.
Topics: Antineoplastic Agents, Phytogenic; Cell Line; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Down-Regulation; Furans; Glucosides; Humans; Neoplasms; Retinoblastoma Protein | 2008 |
Treatment with SI000413, a new herbal formula, ameliorates murine collagen-induced arthritis.
Topics: Animals; Antirheumatic Agents; Arthritis, Rheumatoid; Autoantibodies; Cartilage; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Chromatography, High Pressure Liquid; Collagen Type II; Cytokines; Dose-Response Relationship, Drug; Flow Cytometry; Furans; Glucosides; Interleukin-6; Joints; Lymphocyte Subsets; Male; Mice; Mice, Inbred DBA; Plant Extracts; Plant Preparations | 2008 |
Metabolic profile of the bioactive compounds of burdock (Arctium lappa) seeds, roots and leaves.
Topics: Antioxidants; Arctium; Caffeic Acids; Chlorogenic Acid; Chromatography, Liquid; Cinnamates; Furans; Glucosides; Luteolin; Phenols; Plant Extracts; Plant Leaves; Plant Roots; Quercetin; Quinic Acid; Seeds; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2010 |
Ameliorative effects of arctiin from Arctium lappa on experimental glomerulonephritis in rats.
Topics: Animals; Arctium; DNA; Drugs, Chinese Herbal; Furans; Glomerulonephritis; Glucosides; Interleukin-6; Kidney; Kidney Function Tests; Male; Malondialdehyde; NF-kappa B; Phytotherapy; Proteinuria; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2009 |
Further studies on a human intestinal bacterium Ruminococcus sp. END-1 for transformation of plant lignans to mammalian lignans.
Topics: Biotransformation; Butylene Glycols; Furans; Glucosides; Humans; Intestines; Lignans; Molecular Structure; Ruminococcus; Stereoisomerism | 2009 |
Therapeutic effect of arctiin and arctigenin in immunocompetent and immunocompromised mice infected with influenza A virus.
Topics: Animals; Antiviral Agents; Cells, Cultured; Dogs; Furans; Glucosides; Immunocompetence; Immunocompromised Host; Influenza A virus; Lignans; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred BALB C; Orthomyxoviridae Infections; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Infrared | 2010 |
On-line coupling of counter-current chromatography and macroporous resin chromatography for continuous isolation of arctiin from the fruit of Arctium lappa L.
Topics: Acetates; Adsorption; Arctium; Butanols; Chromatography, High Pressure Liquid; Countercurrent Distribution; Drugs, Chinese Herbal; Fruit; Furans; Glucosides; Porosity; Sodium Chloride | 2010 |
Determination of the major constituents in fruit of Arctium lappa L. by matrix solid-phase dispersion extraction coupled with HPLC separation and fluorescence detection.
Topics: Adsorption; Arctium; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Fruit; Furans; Glucosides; Lignans; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Spectrometry, Fluorescence | 2010 |
Arctigenin isolated from the seeds of Arctium lappa ameliorates memory deficits in mice.
Topics: Acetylcholinesterase; Animals; Arctium; Avoidance Learning; Cholinesterase Inhibitors; Drugs, Chinese Herbal; Functional Food; Furans; Glucosides; Lignans; Male; Maze Learning; Memory Disorders; Mice; Mice, Inbred ICR; Phytotherapy; Plant Extracts; Scopolamine; Seeds; Tacrine | 2011 |
[Study on correlation between ITS sequence of Arctium lappa and quality of Fructus Arctii].
Topics: Arctium; Computational Biology; DNA, Ribosomal Spacer; Drugs, Chinese Herbal; Furans; Genotype; Glucosides; Polymorphism, Genetic; Quality Control; Sequence Analysis, DNA; Software | 2011 |
[Effect of arctiin on mouse podocyte epithelial-mesenchymal transition induced by advanced oxidation protein products].
Topics: Actins; Advanced Oxidation Protein Products; Animals; Cell Line; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Epithelial-Mesenchymal Transition; Furans; Glucosides; Heat-Shock Proteins; Mice; Podocytes; Transcription Factor CHOP | 2012 |
Plasma pharmacokinetics and tissue distribution of arctiin and its main metabolite in rats by HPLC-UV and LC-MS.
Topics: Administration, Oral; Animals; Arctium; Chromatography, High Pressure Liquid; Chromatography, Liquid; Fruit; Furans; Glucosides; Male; Mass Spectrometry; Plants, Medicinal; Rats; Rats, Sprague-Dawley | 2012 |
Effects of arctiin on streptozotocin-induced diabetic retinopathy in Sprague-Dawley rats.
Topics: Animals; Arctium; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Drugs, Chinese Herbal; Furans; Glucosides; Glycated Hemoglobin; Hypoglycemic Agents; Male; Random Allocation; Rats; Rats, Sprague-Dawley; Seeds; Streptozocin | 2012 |
Effect of arctiin on glomerular filtration barrier damage in STZ-induced diabetic nephropathy rats.
Topics: Albuminuria; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Furans; Gene Expression Regulation; Glomerular Filtration Barrier; Glucosides; Glucuronidase; Intracellular Signaling Peptides and Proteins; Kidney Glomerulus; Male; Membrane Proteins; Metabolome; Rats; Rats, Sprague-Dawley; RNA, Messenger; Streptozocin | 2013 |
Simultaneous determination of arctiin and its metabolites in rat urine and feces by HPLC.
Topics: 4-Butyrolactone; Animals; Arctium; Chromatography, High Pressure Liquid; Feces; Fruit; Furans; Glucosides; Lignans; Male; Plant Extracts; Rats, Sprague-Dawley | 2013 |
Alkyl and phenolic glycosides from Saussurea stella.
Topics: Animals; Anti-Inflammatory Agents; Coumaric Acids; Disaccharides; Female; Flavonoids; Furans; Glucosides; Glucuronidase; Glycosides; Hydroxybenzoates; Inflammation; Isoflavones; Lignans; Male; Molecular Structure; Neutrophils; Phytotherapy; Plant Extracts; Platelet Activating Factor; Quinic Acid; Rats, Wistar; Saussurea | 2013 |
[Determination of plasma protein binding rate of arctiin and arctigenin with ultrafiltration].
Topics: Animals; Binding, Competitive; Blood Proteins; Chromatography, High Pressure Liquid; Furans; Glucosides; Humans; Lignans; Male; Protein Binding; Rats; Rats, Sprague-Dawley; Ultrafiltration | 2013 |
Optimization of extraction and purification of arctiin from Fructus arctii and its protection against glucose-induced rat aortic endothelial cell injury.
Topics: Animals; Antioxidants; Aorta; Arctium; Cells, Cultured; Drugs, Chinese Herbal; Endothelial Cells; Furans; Gene Expression; Glucose; Glucosides; Malondialdehyde; Nitric Oxide; Nitric Oxide Synthase Type III; Plant Extracts; Rats; Rats, Wistar | 2014 |
Arctiin induces an UVB protective effect in human dermal fibroblast cells through microRNA expression changes.
Topics: Arctium; Fibroblasts; Furans; Gene Expression Regulation; Glucosides; Humans; MicroRNAs; Plant Extracts; Radiation-Protective Agents; Signal Transduction; Skin; Ultraviolet Rays | 2014 |
Photoprotective effect of arctiin against ultraviolet B-induced damage in HaCaT keratinocytes is mediated by microRNA expression changes.
Topics: Cell Cycle; Cell Death; Cell Line; Computational Biology; DNA Repair; Furans; Glucosides; Humans; Keratinocytes; MicroRNAs; Mitogen-Activated Protein Kinases; Protective Agents; Skin; Ultraviolet Rays; Wnt Signaling Pathway; Wound Healing | 2014 |
Arctigenin but not arctiin acts as the major effective constituent of Arctium lappa L. fruit for attenuating colonic inflammatory response induced by dextran sulfate sodium in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arctium; Colitis; Dextran Sulfate; Dose-Response Relationship, Drug; Fruit; Furans; Glucosides; Lignans; Male; Mesalamine; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase Kinases; Molecular Structure; NF-kappa B; Oxidative Stress; Plant Extracts | 2014 |
Arctiin blocks hydrogen peroxide-induced senescence and cell death though microRNA expression changes in human dermal papilla cells.
Topics: Aging; beta-Galactosidase; Cell Cycle Checkpoints; Cell Death; Cell Line; Cell Survival; Dermis; Down-Regulation; Furans; Glucosides; Hair Follicle; Humans; Hydrogen Peroxide; MicroRNAs; Oligonucleotide Array Sequence Analysis; Reactive Oxygen Species; Up-Regulation | 2014 |
Searching for synergistic bronchodilators and novel therapeutic regimens for chronic lung diseases from a traditional Chinese medicine, Qingfei Xiaoyan Wan.
Topics: Adrenergic beta-2 Receptor Agonists; Animals; Asthma; Bronchodilator Agents; Calcium; Cell Line; Chromatography, High Pressure Liquid; Chronic Disease; Disease Models, Animal; Drug Synergism; Drugs, Chinese Herbal; Ephedrine; Flavonoids; Furans; Glucosides; Guinea Pigs; Humans; Lactones; Lignans; Lung Diseases; Medicine, Chinese Traditional; Myocytes, Smooth Muscle; Trachea | 2014 |
Natural lignans from Arctium lappa modulate P-glycoprotein efflux function in multidrug resistant cancer cells.
Topics: 4-Butyrolactone; Antineoplastic Agents; Arctium; ATP Binding Cassette Transporter, Subfamily B; Benzofurans; Caco-2 Cells; Cell Line, Tumor; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Furans; Glucosides; Humans; Lignans; Molecular Structure; Rhodamine 123; Seeds | 2015 |
Optimization of the processing technology of Fructus Arctii by response surface methodology.
Topics: Arctium; Chemistry, Pharmaceutical; Chlorogenic Acid; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Furans; Glucosides; Hot Temperature; Lignans; Surface Properties; Technology, Pharmaceutical | 2015 |
[Study on High-yield Cultivation Measures for Arctii Fructus].
Topics: Arctium; Crop Production; Drugs, Chinese Herbal; Fertilizers; Furans; Glucosides; Seeds; Soil | 2015 |
Microwave-Assisted Extraction and Purification of Arctiin and Arctigenin from Fructus Arctii by High-Speed Countercurrent Chromatography.
Topics: Acetates; Arctium; Biphenyl Compounds; Chromatography, High Pressure Liquid; Countercurrent Distribution; Ethanol; Free Radical Scavengers; Furans; Glucosides; Hexanes; Hydrochloric Acid; Hydrolysis; Lignans; Liquid-Liquid Extraction; Microwaves; Picrates; Plant Extracts; Solvents; Water | 2016 |
[Study of screening pseudoallergenic substances of Shuanghuanglian injection].
Topics: Animals; Drug Hypersensitivity; Drugs, Chinese Herbal; Furans; Glucosides; Glycosides; Injections; Male; Mice; Mice, Inbred ICR | 2015 |
Inhibition of UDP-Glucuronosyltransferase (UGT) Isoforms by Arctiin and Arctigenin.
Topics: Furans; Glucosides; Glucuronosyltransferase; Herb-Drug Interactions; Humans; Isoenzymes; Kinetics; Lignans | 2016 |
[Arctiin ameliorates advanced oxidation protein product-induced epithelial-to- mesenchymal transition in HK-2 cells by inhibiting endoplasmic reticulum stress].
Topics: Advanced Oxidation Protein Products; Antigens, CD; Cadherins; Cell Line; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Epithelial Cells; Epithelial-Mesenchymal Transition; Furans; Glucosides; Heat-Shock Proteins; Humans; Kidney Tubules; Oxidative Stress; Reactive Oxygen Species; Vimentin | 2016 |
Room temperature ionic liquids-based salting-in strategy for counter-current chromatography in the separation of arctiin.
Topics: Arctium; Countercurrent Distribution; Furans; Glucosides; Ionic Liquids; Solvents; Temperature | 2016 |
Isolation and Characterization of a Human Intestinal Bacterium Eggerthella sp. AUH-JLD49s for the Conversion of (-)-3'-Desmethylarctigenin.
Topics: Actinobacteria; Biotransformation; Cell Line, Tumor; Cell Proliferation; Feces; Female; Furans; Glucosides; Humans; Intestines; Lignans; Molecular Structure; Spectrometry, Mass, Electrospray Ionization | 2017 |
Arctiin regulates collagen type 1α chain 1 mRNA expression in human dermal fibroblasts via the miR‑378b‑SIRT6 axis.
Topics: Cell Survival; Cells, Cultured; Collagen Type I; Collagen Type I, alpha 1 Chain; Dermis; Fibroblasts; Furans; Gene Expression Regulation; Glucosides; Humans; MicroRNAs; Plant Extracts; RNA Interference; RNA, Messenger; Sirtuins; Ultraviolet Rays | 2017 |
Arctiin protects against cardiac hypertrophy through inhibiting MAPKs and AKT signaling pathways.
Topics: Administration, Oral; Animals; Arctium; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Fibrosis; Furans; Glucosides; Male; MAP Kinase Signaling System; Mice, Inbred C57BL; Myocytes, Cardiac; Phytotherapy; Proto-Oncogene Proteins c-akt; Signal Transduction | 2017 |
Arctiin Prevents LPS-Induced Acute Lung Injury via Inhibition of PI3K/AKT Signaling Pathway in Mice.
Topics: Acute Lung Injury; Animals; Furans; Glucosides; Lipopolysaccharides; Male; Mice; Mice, Inbred BALB C; NF-kappa B; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction | 2018 |
Arctiin is a pharmacological inhibitor of STAT3 phosphorylation at tyrosine 705 residue and potentiates bortezomib-induced apoptotic and anti-angiogenic effects in human multiple myeloma cells.
Topics: Angiogenesis Inhibitors; Apoptosis; Arctium; Bortezomib; Cell Line, Tumor; Cell Proliferation; Drugs, Chinese Herbal; Furans; Glucosides; Humans; Multiple Myeloma; Phosphorylation; Plant Extracts; Receptor-Like Protein Tyrosine Phosphatases, Class 4; Signal Transduction; STAT3 Transcription Factor; Tyrosine | 2019 |
Changes in chemical components and antitumor activity during the heating process of Fructus Arctii.
Topics: Arctium; Cell Proliferation; Chlorogenic Acid; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Fruit; Furans; Glucosides; HL-60 Cells; Humans; Lignans; Medicine, Chinese Traditional; Quinic Acid | 2019 |
Arctiin protects rat heart against ischemia/reperfusion injury via a mechanism involving reduction of necroptosis.
Topics: Animals; Cardiotonic Agents; Cell Line; Disease Models, Animal; Drugs, Chinese Herbal; Furans; Glucosides; Humans; Male; Mitochondria; Myocardial Reperfusion Injury; Myocytes, Cardiac; Necroptosis; Protein Kinases; Protein Serine-Threonine Kinases; Rats; Reactive Oxygen Species; Receptor-Interacting Protein Serine-Threonine Kinases; Signal Transduction | 2020 |
Arctiin attenuates high glucose-induced human retinal capillary endothelial cell proliferation by regulating ROCK1/PTEN/PI3K/Akt/VEGF pathway in vitro.
Topics: Biomarkers; Cell Cycle Checkpoints; Cell Proliferation; Diabetic Retinopathy; Endothelial Cells; Fluorescent Antibody Technique; Furans; Glucose; Glucosides; Humans; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Retinal Vessels; rho-Associated Kinases; Signal Transduction; Vascular Endothelial Growth Factor A | 2020 |
Arctiin abrogates osteoclastogenesis and bone resorption via suppressing RANKL-induced ROS and NFATc1 activation.
Topics: Animals; Antioxidant Response Elements; Bone Density Conservation Agents; Bone Resorption; Calcium Signaling; Disease Models, Animal; Female; Furans; Glucosides; Kelch-Like ECH-Associated Protein 1; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; NF-E2-Related Factor 2; NFATC Transcription Factors; Osteoclasts; Osteogenesis; Osteoporosis; Ovariectomy; RANK Ligand; RAW 264.7 Cells; Reactive Oxygen Species | 2020 |
Antidepressive Effect of Arctiin by Attenuating Neuroinflammation via HMGB1/TLR4- and TNF-α/TNFR1-Mediated NF-κB Activation.
Topics: Animals; Antidepressive Agents; Depression; Furans; Glucosides; HMGB1 Protein; Mice; NF-kappa B; Receptors, Tumor Necrosis Factor, Type I; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2020 |
An integrated strategy for revealing the pharmacological changes based on metabolites profiling and network pharmacology: Arctiin as an example.
Topics: Animals; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Furans; Glucosides; Male; Mass Spectrometry; Metabolic Networks and Pathways; Protein Interaction Maps; Rats; Rats, Sprague-Dawley; Tissue Distribution | 2020 |
[Arctiin antagonizes triptolide-induced renal toxicity in rats via anti-inflammatory pathway].
Topics: Animals; Anti-Inflammatory Agents; Diterpenes; Epoxy Compounds; Furans; Glucosides; Kidney; Phenanthrenes; Rats; Rats, Sprague-Dawley | 2020 |
Arctiin Antagonizes Triptolide-Induced Hepatotoxicity via Activation of Nrf2 Pathway.
Topics: Animals; Apoptosis; Cell Line, Tumor; Chemical and Drug Induced Liver Injury; Diterpenes; Epoxy Compounds; Furans; Glucosides; Hep G2 Cells; Humans; Liver; Mice; Mice, Inbred BALB C; NF-E2-Related Factor 2; Oxidative Stress; Phenanthrenes; Protective Agents; Signal Transduction | 2020 |
Arctiin suppresses H9N2 avian influenza virus-mediated inflammation via activation of Nrf2/HO-1 signaling.
Topics: A549 Cells; Animals; Anti-Inflammatory Agents; China; Dogs; Furans; Glucosides; Heme Oxygenase-1; Humans; Influenza A Virus, H9N2 Subtype; Madin Darby Canine Kidney Cells; Molecular Structure; NF-E2-Related Factor 2; Plant Extracts | 2021 |
Arctiin elevates osteogenic differentiation of MC3T3-E1 cells by modulating cyclin D1.
Topics: Animals; Cyclin D1; Furans; Glucosides; Mice; Osteoblasts; Osteogenesis; Osteoporosis | 2022 |
Arctiin-reinforced antioxidant microcarrier antagonizes osteoarthritis progression.
Topics: Animals; Antioxidants; Chondrocytes; Furans; Glucosides; Mice; Osteoarthritis | 2022 |
Synthesis, Structural Elucidation, and Anti-Inflammatory Activity of a Water-Soluble Derivative of Arctiin.
Topics: Animals; Anti-Inflammatory Agents; Furans; Glucosides; Glucuronides; Mice; Water | 2023 |
A biologically active fructan from the roots of Arctium lappa L., var. Herkules.
Topics: Animals; Antitussive Agents; Arctium; Carbohydrate Conformation; Cats; Cells, Cultured; Chromatography, Gel; Chromatography, Ion Exchange; Cough; Dose-Response Relationship, Drug; Female; Fructans; Magnetic Resonance Spectroscopy; Male; Mitogens; Molecular Structure; Plant Roots; Rats; Rats, Wistar; Spectroscopy, Fourier Transform Infrared; Thymus Gland; Zymosan | 2003 |
Diarctigenin, a lignan constituent from Arctium lappa, down-regulated zymosan-induced transcription of inflammatory genes through suppression of DNA binding ability of nuclear factor-kappaB in macrophages.
Topics: Animals; Anti-Inflammatory Agents; Arctium; Cells, Cultured; Cytokines; Dinoprostone; DNA; Female; Gene Expression Regulation; Interleukin-6; Lignans; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred C57BL; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Promoter Regions, Genetic; Signal Transduction; Tumor Necrosis Factor-alpha; Zymosan | 2008 |
[Research on the preparative method of Arctigenin].
Topics: Arctium; Flavonoids; Furans; Glucosides; Hydrogen-Ion Concentration; Hydrolysis; Lignans; Technology, Pharmaceutical; Temperature; Time Factors | 2012 |
Hepatoprotective activity of twelve novel 7'-hydroxy lignan glucosides from Arctii Fructus.
Topics: Apoptosis; Arctium; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Chemical and Drug Induced Liver Injury; Circular Dichroism; Drugs, Chinese Herbal; Fruit; Glucosides; Humans; Lignans; Liver Neoplasms; Magnetic Resonance Spectroscopy; Molecular Structure | 2014 |
Four new neolignan glucosides from the fruits of Arctium lappa.
Topics: Arctium; Drugs, Chinese Herbal; Fruit; Glucosides; Lignans; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oxotremorine; Stereoisomerism | 2015 |