arcaine and spermidine

arcaine has been researched along with spermidine in 30 studies

Research

Studies (30)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (3.33)	18.7374
1990's	12 (40.00)	18.2507
2000's	9 (30.00)	29.6817
2010's	8 (26.67)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Britt, M; Paschetto, KA; Powel, RJ; Pullan, LM; Stumpo, RJ	1
Reynolds, IJ	3
Canton, H; Colpaert, F; Lehmann, J	1
Johnson, KM; Sacaan, AI	2
Hiramatsu, M; Mori, A; Numoto, A; Robin, Y	1
Hoss, W; Kothapalli, MR; Periyasamy, S	1
Berrino, L; Filippelli, A; Leyva, J; Maione, S; Pizzirusso, A; Rossi, F; Vitagliano, S	1
Foster, AC; Grimwood, S; Struthers, L	1
Burns, MA; Palmer, AM	1
Balster, RL; Nicholson, KL	1
Boemo, RL; Jurach, A; Mello, CF; Obregon, AD; Rojas, DB; Rubin, MA; Souza, DO; Zanolla, GR	1
Boemo, RL; Fenili, AC; Jurach, A; Mello, CF; Oliveira, DM; Rubin, MA; Stiegemeier, JA; Volkweis, MA	1
Gebka, J; Kaminska, E; Mikolajczak, P; Niedopad, L; Okulicz-Kozaryn, I; Polanska, A	1
Gibson, DA; Harris, BR; Littleton, JM; Rogers, DT	1
Littleton, JM; Mulholland, PJ; Nath, A; Prendergast, MA; Rogers, DT; Self, RL; Wilkins, LH	1
Berlese, DB; dos Santos, TL; Fenili, AC; Mello, CF; Oliveira, DM; Rubin, MA; Stiegemeier, JA; Volkweis, MA	1
Bellé, NA; Dalmolin, GD; Fonini, G; Rocha, JB; Rubin, MA	1
Camera, K; Ceretta, AP; Mello, CF; Rubin, MA	1
Ferreira, J; Fighera, MR; Fiorenza, NG; Furian, AF; Mello, CF; Oliveira, MS; Royes, LF; Rubin, MA	1
Barron, S; Bochi, GV; da Rosa, MM; Ferreira, J; Gomes, GM; Mello, CF; Rubin, MA	1
Bochi, GV; Calixto, JB; Dutra, RC; Fachinetto, R; Ferreira, J; Guerra, GP; Mello, CF; Pazini, AM; Rubin, MA	1
Carvalho, FB; Ferreira, J; Girardi, BA; Marisco, PC; Mello, CF; Oliveira, MS; Rubin, MA; Tonello, R	1
Mello, CF; Ribeiro, DA; Rubin, MA; Signor, C	1
Mello, CF; Porto, GP; Ribeiro, DA; Rubin, MA; Signor, C	1
Bär, J; Dalmolin, GD; Gomes, GM; Karpova, A; Kreutz, MR; Mello, CF; Rubin, MA	1
Gais, MA; Girardi, BA; Mello, CF; Muller, M; Ribeiro, DA; Rubin, MA; Signor, C	1
Funck, VR; Gais, MA; Girardi, BA; Mello, CF; Oliveira, MS; Rubin, MA; Signor, C; Temp, FR	1

Other Studies

30 other study(ies) available for arcaine and spermidine

Article	Year
Neomycin is an agonist at a polyamine site on the N-methyl-D-aspartate receptor. Journal of neurochemistry, 1992, Volume: 59, Issue:6 Topics: Adrenergic alpha-Antagonists; Animals; Biguanides; Magnesium; Male; Neomycin; Phencyclidine; Piperazines; Piperidines; Polyamines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spermidine; Synaptic Membranes; Tritium	1992
Interactions between zinc and spermidine on the N-methyl-D-aspartate receptor complex: clues to the mechanism of action of 1,10-bis(guanidino)decane and pentamidine. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 263, Issue:2 Topics: Animals; Biguanides; Binding Sites; Brain Chemistry; Diethyl Pyrocarbonate; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Guanidines; Pentamidine; Rats; Receptors, N-Methyl-D-Aspartate; Spermidine; Zinc	1992
Glutamate and glycine co-activate while polyamines merely modulate the NMDA receptor complex. Progress in neuro-psychopharmacology & biological psychiatry, 1991, Volume: 15, Issue:2 Topics: 2-Amino-5-phosphonovalerate; Adrenergic alpha-Antagonists; Animals; Biguanides; Binding, Competitive; Biogenic Polyamines; Biotransformation; Brain; Dizocilpine Maleate; Glutamates; Glutamic Acid; Glycine; In Vitro Techniques; Kynurenic Acid; Piperidines; Rats; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine	1991
Competitive inhibition of magnesium-induced [3H]N-(1-[thienyl] cyclohexyl)piperidine binding by arcaine: evidence for a shared spermidine-magnesium binding site. Molecular pharmacology, 1990, Volume: 38, Issue:5 Topics: Animals; Biguanides; Binding Sites; Binding, Competitive; Dose-Response Relationship, Drug; Drug Interactions; Glutamates; Glutamic Acid; Glycine; In Vitro Techniques; Magnesium; Phencyclidine; Rats; Receptors, N-Methyl-D-Aspartate; Spermidine; Strychnine	1990
Spermidine reverses arcaine's inhibition of N-methyl-D-aspartate-induced hippocampal [3H]norepinephrine release. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:3 Topics: Animals; Biguanides; Binding Sites; Dimethyl Sulfoxide; Hippocampus; Hydrogen-Ion Concentration; Intracellular Fluid; Male; N-Methylaspartate; Norepinephrine; Polyamines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Spermidine; Tritium	1990
Arcaine is a competitive antagonist of the polyamine site on the NMDA receptor. European journal of pharmacology, 1990, Feb-27, Volume: 177, Issue:3 Topics: Biguanides; Binding, Competitive; Biogenic Polyamines; Dibenzocycloheptenes; Dizocilpine Maleate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spermidine	1990
[Convulsant action of the diguanide derivatives hirudonine, arcaine and audouine]. Comptes rendus des seances de la Societe de biologie et de ses filiales, 1981, Volume: 175, Issue:6 Topics: Administration, Topical; Amidines; Animals; Biguanides; Convulsants; Electroencephalography; Motor Cortex; Rabbits; Somatosensory Cortex; Spermidine; Time Factors	1981
[3H]CGP 39653 binding to the agonist site of the N-methyl-D-aspartate receptor is modulated by Mg2+ and polyamines independently of the arcaine-sensitive polyamine site. Journal of neurochemistry, 1994, Volume: 62, Issue:1 Topics: 2-Amino-5-phosphonovalerate; Animals; Biguanides; Binding Sites; Binding, Competitive; Brain; Cell Membrane; Glycine; Kinetics; Magnesium; Polyamines; Rats; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine; Tritium	1994
Regulation of the phosphoinositide cascade by polyamines in brain. Journal of neurochemistry, 1994, Volume: 63, Issue:4 Topics: Agmatine; Animals; Biguanides; Calcium; Cell Membrane; Cerebral Cortex; Deoxycholic Acid; Guanosine 5'-O-(3-Thiotriphosphate); Homeostasis; Kinetics; Male; Phosphatidylinositols; Polyamines; Rats; Spermidine; Spermine	1994
Effects of the polyamine spermidine on NMDA-induced arterial hypertension in freely moving rats. Neuropharmacology, 1994, Volume: 33, Issue:6 Topics: Animals; Biguanides; Blood Pressure; Drug Synergism; Hypertension; Male; Microinjections; N-Methylaspartate; Periaqueductal Gray; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spermidine	1994
Polyamines modulate [3H]L-689,560 binding to the glycine site of the NMDA receptor from rat brain. European journal of pharmacology, 1994, Jan-01, Volume: 266, Issue:1 Topics: Aminoquinolines; Animals; Biguanides; Binding, Competitive; Cerebral Cortex; Diamines; Dose-Response Relationship, Drug; Glycine; Hippocampus; Polyamines; Putrescine; Rats; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine	1994
Preservation of redox, polyamine, and glycine modulatory domains of the N-methyl-D-aspartate receptor in Alzheimer's disease. Journal of neurochemistry, 1994, Volume: 62, Issue:1 Topics: Aged; Aged, 80 and over; Alzheimer Disease; Analysis of Variance; Biguanides; Binding Sites; Brain; Cell Membrane; Cerebral Cortex; Dithionitrobenzoic Acid; Dizocilpine Maleate; Female; Frontal Lobe; Glycine; Humans; Male; Middle Aged; Organ Specificity; Oxidation-Reduction; Radioligand Assay; Receptors, N-Methyl-D-Aspartate; Spermidine; Temporal Lobe	1994
Phencyclidine-like discriminative stimulus effects of polyamine modulators of N-methyl-D-aspartate receptor activity in rats. Neuroscience letters, 1998, Aug-28, Volume: 253, Issue:1 Topics: Animals; Biguanides; Discrimination Learning; Male; Motivation; Phencyclidine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reinforcement, Psychology; Spermidine; Spermine	1998
Intrahippocampal spermidine administration improves inhibitory avoidance performance in rats. Behavioural pharmacology, 2000, Volume: 11, Issue:1 Topics: Animals; Avoidance Learning; Biguanides; Hippocampus; Injections; Male; Motor Activity; Rats; Rats, Wistar; Spermidine	2000
Intra-amygdala spermidine administration improves inhibitory avoidance performance in rats. European journal of pharmacology, 2001, Jun-29, Volume: 423, Issue:1 Topics: Amygdala; Animals; Avoidance Learning; Behavior, Animal; Biguanides; Dose-Response Relationship, Drug; Male; Motor Activity; Rats; Rats, Wistar; Spermidine	2001
Effects of acamprosate and some polyamine site ligands of NMDA receptor on short-term memory in rats. European journal of pharmacology, 2002, May-24, Volume: 444, Issue:1-2 Topics: Acamprosate; Administration, Oral; Animals; Biguanides; Dose-Response Relationship, Drug; Drug Interactions; Male; Memory, Short-Term; Motor Activity; Piperidines; Polyamines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Sleep; Spermidine; Taurine	2002
Radioligand binding studies reveal agmatine is a more selective antagonist for a polyamine-site on the NMDA receptor than arcaine or ifenprodil. Brain research, 2002, Oct-11, Volume: 952, Issue:1 Topics: Agmatine; Animals; Biguanides; Binding Sites; Binding, Competitive; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Male; Piperidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spermidine; Tritium	2002
Neurotoxic effects of the human immunodeficiency virus type-1 transcription factor Tat require function of a polyamine sensitive-site on the N-methyl-D-aspartate receptor. Brain research, 2002, Nov-08, Volume: 954, Issue:2 Topics: Animals; ATPases Associated with Diverse Cellular Activities; Biguanides; Brain; Cerebellum; Cerebral Cortex; Culture Techniques; Dizocilpine Maleate; DNA-Binding Proteins; Excitatory Amino Acid Antagonists; Female; Hippocampus; HIV-1; Male; Neurons; Neurotoxins; Proteasome Endopeptidase Complex; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spermidine	2002
Intra-amygdala administration of polyamines modulates fear conditioning in rats. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Mar-03, Volume: 24, Issue:9 Topics: Amygdala; Animals; Behavior, Animal; Biguanides; Biogenic Polyamines; Catheterization; Conditioning, Classical; Drug Administration Routes; Fear; Male; Maze Learning; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spatial Behavior; Spermidine	2004
Polyamines reduces lipid peroxidation induced by different pro-oxidant agents. Brain research, 2004, May-22, Volume: 1008, Issue:2 Topics: Animals; Antioxidants; Biguanides; Biogenic Polyamines; Dizocilpine Maleate; Edetic Acid; Iron; Lipid Peroxidation; Nitroprusside; Oxidants; Quinolinic Acid; Rats; Rats, Wistar; Spermidine; Spermine; Thiobarbituric Acid Reactive Substances	2004
Systemic administration of polyaminergic agents modulate fear conditioning in rats. Psychopharmacology, 2007, Volume: 192, Issue:4 Topics: Animals; Behavior, Animal; Biguanides; Conditioning, Classical; Dizocilpine Maleate; Fear; Injections, Intraperitoneal; Male; Memory; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spermidine; Time Factors	2007
The involvement of the polyamines binding sites at the NMDA receptor in creatine-induced spatial learning enhancement. Behavioural brain research, 2008, Feb-11, Volume: 187, Issue:1 Topics: Animals; Biguanides; Binding Sites; Creatine; Hippocampus; Male; Maze Learning; Microinjections; Polyamines; Rats; Receptors, N-Methyl-D-Aspartate; Space Perception; Spermidine; Stimulation, Chemical	2008
Polyaminergic agents modulate contextual fear extinction in rats. Neurobiology of learning and memory, 2010, Volume: 93, Issue:4 Topics: Animals; Biguanides; Conditioning, Classical; Excitatory Amino Acid Antagonists; Extinction, Psychological; Fear; Freezing Reaction, Cataleptic; Male; Neuropsychological Tests; Nootropic Agents; Piperidines; Polyamines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spermidine	2010
Hippocampal PKA/CREB pathway is involved in the improvement of memory induced by spermidine in rats. Neurobiology of learning and memory, 2011, Volume: 96, Issue:2 Topics: Animals; Avoidance Learning; Biguanides; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Hippocampus; Memory; Phosphorylation; Rats; Signal Transduction; Spermidine	2011
Spermidine decreases Na⁺,K⁺-ATPase activity through NMDA receptor and protein kinase G activation in the hippocampus of rats. European journal of pharmacology, 2012, Jun-05, Volume: 684, Issue:1-3 Topics: Animals; Biguanides; Carbazoles; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dizocilpine Maleate; Enzyme Activation; Hippocampus; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Sodium-Potassium-Exchanging ATPase; Spermidine	2012
Polyaminergic agents modulate the reconsolidation of conditioned fear. Neurobiology of learning and memory, 2013, Volume: 104 Topics: Animals; Biguanides; Conditioning, Psychological; Fear; Male; Memory; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spermidine	2013
Spermidine improves fear memory persistence. European journal of pharmacology, 2014, May-05, Volume: 730 Topics: Animals; Biguanides; Dose-Response Relationship, Drug; Fear; Male; Memory; Rats; Rats, Wistar; Spermidine; Time Factors	2014
Inhibition of the polyamine system counteracts β-amyloid peptide-induced memory impairment in mice: involvement of extrasynaptic NMDA receptors. PloS one, 2014, Volume: 9, Issue:6 Topics: Amyloid beta-Peptides; Animals; Biguanides; Binding Sites; Cell Nucleus; Dendritic Spines; Exploratory Behavior; Hippocampus; Male; Memory Disorders; Mice; Nerve Tissue Proteins; Peptide Fragments; Piperidines; Polyamines; Receptors, N-Methyl-D-Aspartate; Spermidine; Synapses	2014
Spermidine-induced improvement of reconsolidation of memory involves calcium-dependent protein kinase in rats. Learning & memory (Cold Spring Harbor, N.Y.), 2016, Volume: 23, Issue:1 Topics: Analysis of Variance; Animals; Anisomycin; Biguanides; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fear; Hippocampus; Indoles; Male; Maleimides; Memory; Protein Kinases; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Spermidine	2016
Intrahippocampal infusion of spermidine improves memory persistence: Involvement of protein kinase A. Neurobiology of learning and memory, 2016, Volume: 131 Topics: Animals; Anisomycin; Behavior, Animal; Biguanides; Cyclic AMP-Dependent Protein Kinases; Fear; Hippocampus; Isoquinolines; Male; Memory, Long-Term; Nootropic Agents; Polyamines; Protein Kinase Inhibitors; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Spermidine; Sulfonamides	2016