arbutin and harpagide

In this work, the phytochemical analysis of Teucrium chamaedrys L. collected in Italy was reported. Eight compounds were isolated and identified by means of classical column chromatography and spectroscopic techniques, such as NMR and MS. In detail, these compounds were: verbascoside (1), forsythoside b (2), samioside (3), alyssonoside (4), harpagide (5), 8-O-acetyl-harpagide (6), cirsiliol (7) and β-arbutin (8). The presence of these compounds, in particular iridoids and phenyl-ethanoid glycosides, has a chemotaxonomic relevance and results to be in perfect accordance with the current botanical classification of the species. In addition, it provides a phytochemical rationale for the use of this particular plant in the ethno-pharmacological field. Conversely, it is worth of mention the absence of potentially toxic components, unlike to what observed in other species of the genus which can no longer be used for ethno-medicinal purposes.

Topics: Arbutin; Caffeic Acids; Glucosides; Glycosides; Iridoid Glycosides; Italy; Magnetic Resonance Spectroscopy; Molecular Structure; Phenols; Plant Extracts; Polyphenols; Pyrans; Teucrium

In this study, we report the isolation and identification of several compounds present in the polar fraction of Stachys germanica L. subsp. salviifolia (Ten.) Gams, collected in the protected area of Majella National Park. In particular, we have isolated and identified harpagide, 7-β-hydroxy-harpagide, ajugol, 5-allosyloxy-aucubin, verbascoside and, for the first time in this genus, arbutin.

Topics: Arbutin; Glucosides; Glycosides; Iridoid Glucosides; Iridoid Glycosides; Italy; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Phenols; Plant Components, Aerial; Plant Extracts; Pyrans; Stachys