aranidipine has been researched along with dihydropyridines in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.35) | 18.7374 |
| 1990's | 14 (60.87) | 18.2507 |
| 2000's | 5 (21.74) | 29.6817 |
| 2010's | 3 (13.04) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Haruno, A; Kanda, A; Miyake, H; Nagasaka, M | 1 |
| Ebihara, A; Fujimura, A; Kumagai, Y; Ohashi, K; Sakamoto, K; Shiga, T; Sudo, T; Tateishi, T | 1 |
| Iida, Y; Imai, T; Kinouchi, Y; Otagiri, M; Takeichi, Y | 1 |
| Maniwa, M; Marunaka, T; Matsushima, E; Umeno, Y | 1 |
| Arakawa, K; Kajiyama, G; Kusukawa, R; Mashiba, H; Nonaka, K; Sasaki, J; Shichiri, M; Sunaga, T; Tanaka, N | 1 |
| Haruno, A; Ichihara, K; Kanda, A; Miyake, H; Miyoshi, K; Nagasaka, M; Okumura, K; Tanahashi, Y | 1 |
| Ichihara, K; Kamei, H; Kanda, A; Miyake, H; Miyoshi, K; Nagasaka, M | 1 |
| Ichihara, K; Mori, H; Nagasaka, M; Okumura, K | 1 |
| Hashimoto, T; Kapuku, K; Kusano, S; Suzuki, S; Utsunomiya, T; Yano, K | 1 |
| Ichihara, K; Nagasaka, M; Oda, N; Okumura, K; Tajima, K | 1 |
| Kanda, A; Miyake, H; Miyoshi, K; Nakano, M; Nozawa, Y | 1 |
| Kimura, R; Miyake, H; Nozawa, Y; Ohkura, T; Uchida, S; Yamada, S | 1 |
| Ichihara, K; Kamei, H; Miyake, H; Miyoshi, K; Nagasaka, M | 1 |
| Ichihara, K; Nagasaka, M; Okumura, K | 1 |
| Ichihara, K; Kamei, H; Kanda, A; Kanno, T; Miyake, H; Miyoshi, K; Nagasaka, M; Okumura, K | 1 |
| Fujiwara, K; Hayashi, K; Honda, M; Nakamura, A; Ozawa, Y; Saruta, T | 1 |
| Masumiya, H; Shigenobu, K; Tanaka, H; Tanaka, Y | 1 |
| Hasegawa, K; Hayashi, K; Homma, K; Kanda, T; Sugano, N; Takamatsu, I; Tatematsu, S; Wakino, S; Yoshioka, K | 1 |
| Huang, Y; Jiang, J; Li, Y; Liu, H; Tian, L; Xu, L | 1 |
| Huang, Y; Jiang, J; Li, Y; Tian, L; Xu, L | 1 |
| Chen, GL; Fan, CM; Li, HM; Li, YS; Lin, YZ; Pang, HM; Wang, L; Wu, SY; Yan, LR; Yu, J; Zhao, RP | 1 |
| Chen, L; Hua, Q; Jiang, H; Jiao, Y; Jin, H; Ke, YN; Sun, RH; Wang, Y; Yang, HY; Zheng, JT | 1 |
| Chen, L; Jiao, Y; Jin, H; Ke, YN; Li, DY; Liu, MX; Wang, BY; Wang, L; Wang, Y; Yang, HY; Zhao, XL; Zheng, JT | 1 |
6 trial(s) available for aranidipine and dihydropyridines
| Article | Year |
|---|---|
Effect of diltiazem on the pharmacokinetics of MPC-1304, a new calcium channel blocker.
Topics: Administration, Oral; Adult; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Diltiazem; Double-Blind Method; Drug Administration Schedule; Half-Life; Heart Rate; Hemodynamics; Humans; Male | 1992 |
Effects of a new calcium channel blocker, MPC-1304, on blood pressure, serum lipoproteins and serum carbohydrate metabolism in patients with essential hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Apolipoprotein A-II; Apolipoproteins; Atenolol; Blood Glucose; Blood Pressure; C-Peptide; Calcium Channel Blockers; Dihydropyridines; Heart Rate; Hemoglobins; Humans; Hypertension; Insulin; Lipoproteins; Middle Aged; Treatment Outcome | 1995 |
Pharmacokinetic and pharmacodynamic characteristics of aranidipine sustained-release, enteric-coated tablets in healthy Chinese men: a phase I, randomized, open-label, single- and multiple-dose study.
Topics: Adult; Calcium Channel Blockers; Delayed-Action Preparations; Dihydropyridines; Dose-Response Relationship, Drug; Humans; Male; Middle Aged; Tablets, Enteric-Coated | 2008 |
Efficacy and safety of aranidipine enteric-coated tablets compared with amlodipine in Chinese patients with mild to moderate essential hypertension: a multicenter, randomized, double-blind, parallel-controlled clinical trial.
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Dihydropyridines; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Hypertension; Male; Middle Aged; Tablets, Enteric-Coated | 2012 |
[The effects of aranidipine on ambulatory blood pressures in patients with mild to moderate essential hypertension].
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Dihydropyridines; Essential Hypertension; Female; Humans; Hypertension; Male; Middle Aged; Young Adult | 2013 |
[Efficacy and safety of aranidipine in Chinese patients with mild-to-moderate essential hypertension].
Topics: Antihypertensive Agents; Dihydropyridines; Double-Blind Method; Essential Hypertension; Felodipine; Female; Humans; Hypertension; Male; Middle Aged | 2013 |
17 other study(ies) available for aranidipine and dihydropyridines
| Article | Year |
|---|---|
Antihypertensive effects of MPC-1304, a novel calcium antagonist, in experimental hypertensive rats and dogs.
Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Coronary Circulation; Dihydropyridines; Dogs; Heart Rate; Hypertension; Hypertension, Renal; Nicardipine; Nifedipine; Nisoldipine; Nitrendipine; Rats; Rats, Inbred SHR; Rats, Wistar | 1992 |
Simultaneous determination of a new dihydropyridine calcium antagonist (MPC-1304) and its metabolite in dog plasma by high-performance liquid chromatography with electrochemical detection.
Topics: Animals; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Dihydropyridines; Dogs; Electrochemistry; Toluene | 1991 |
Gas chromatographic-negative-ion chemical ionization mass spectrometric determination of a new dihydropyridine calcium antagonist (MPC-1304) and its metabolites in human plasma and urine.
Topics: Animals; Anions; Calcium Channel Blockers; Chemical Phenomena; Chemistry; Dihydropyridines; Dogs; Gas Chromatography-Mass Spectrometry; Humans | 1988 |
Cardiovascular profile of MPC-1304, a novel dihydropyridine calcium antagonist: comparison with other calcium antagonists.
Topics: Animals; Arteriosclerosis; Atrioventricular Node; Calcium Channel Blockers; Cardiovascular Diseases; Cardiovascular System; Coronary Circulation; Dihydropyridines; Dogs; Electric Stimulation; Female; Guinea Pigs; Heart Atria; In Vitro Techniques; Male; Myocardial Contraction; Rabbits | 1993 |
MPC-1304, another type of dihydropyridine, possessing highly potent vasodilating action.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta, Thoracic; Binding, Competitive; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; Dogs; Female; Hemodynamics; In Vitro Techniques; Male; Muscle Proteins; Rats; Rats, Inbred SHR; Rats, Wistar; Swine; Vasodilation; Vasodilator Agents | 1993 |
Effects of MPC-1304, a novel Ca2+ entry blocker, on alpha-adrenoceptor-mediated pressor responses in pithed rats.
Topics: Administration, Oral; Adrenergic alpha-Agonists; Animals; Blood Pressure; Brimonidine Tartrate; Calcium Channel Blockers; Decerebrate State; Dihydropyridines; Electric Stimulation; Nifedipine; Norepinephrine; Phenylephrine; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Spinal Cord; Sympathetic Nervous System | 1993 |
Effect of a new calcium antagonist on hemodynamics at rest and exercise loading in patients with essential hypertension.
Topics: Aged; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Exercise; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Myocardial Contraction; Pulse; Rest; Vascular Resistance | 1993 |
Calcium entry blocking activities of MPC-1304 and of its enantiomers and metabolites.
Topics: Animals; Blood Pressure; Calcium; Calcium Channel Blockers; Dihydropyridines; Hypertension; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Rabbits; Rats; Rats, Inbred SHR; Stereoisomerism | 1993 |
Regional vascular effects of MPC-1304, a novel dihydropyridine derivative, in conscious normotensive and spontaneously hypertensive rats.
Topics: Animals; Blood Flow Velocity; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Heart Rate; Hypertension; Male; Nifedipine; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1996 |
Receptor occupation and pharmacokinetics of MPC-1304, a new Ca2+ channel antagonist, in spontaneously hypertensive rats.
Topics: Administration, Oral; Animals; Aorta; Binding, Competitive; Calcium Channel Blockers; Cerebral Cortex; Dihydropyridines; Heart; Hypertension; Male; Nifedipine; Rats; Rats, Inbred SHR; Time Factors | 1995 |
Contribution of aranidipine metabolites with slow binding kinetics to the vasodilating activity of aranidipine.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Dihydropyridines; Dogs; Female; Guinea Pigs; Kinetics; Male; Nifedipine; Regional Blood Flow; Vasodilator Agents | 1997 |
Effects of aranidipine, a novel calcium channel blocker, on mechanical responses of the isolated rat portal vein: comparison with typical calcium channel blockers and potassium channel openers.
Topics: Animals; Calcium Channel Blockers; Dihydropyridines; In Vitro Techniques; Male; Portal Vein; Potassium Channels; Potassium Chloride; Rats; Rats, Wistar; Tetraethylammonium Compounds; Vasoconstriction | 1997 |
Renal effects of the calcium channel blocker aranidipine and its active metabolite in anesthetized dogs and conscious spontaneously hypertensive rats.
Topics: Administration, Oral; Animals; Blood Pressure; Calcium Channel Blockers; Creatinine; Dihydropyridines; Diuretics; Dogs; Dose-Response Relationship, Drug; Drug Tolerance; Glomerular Filtration Rate; Hemodynamics; Hypertension; Infusions, Intra-Arterial; Kidney; Male; Nifedipine; Organ Size; p-Aminohippuric Acid; Potassium; Rats; Rats, Inbred SHR; Renal Circulation; Sodium; Time Factors; Trichlormethiazide; Urine | 1998 |
Distinct action of aranidipine and its active metabolite on renal arterioles, with special reference to renal protection.
Topics: Animals; Arterioles; Blood Pressure; Blood Urea Nitrogen; Calcium Channel Blockers; Creatinine; Dihydropyridines; In Vitro Techniques; Kidney; Male; Nephrectomy; Norepinephrine; Proteinuria; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Circulation; Sodium Chloride, Dietary; Systole | 2000 |
Inhibition of T-type and L-type Ca(2+) currents by aranidipine, a novel dihydropyridine Ca(2+) antagonist.
Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Dihydropyridines; Guinea Pigs; Heart Ventricles; In Vitro Techniques; Male; Patch-Clamp Techniques; Potassium Channels; Rabbits; Sinoatrial Node; Ventricular Function | 2000 |
Divergent action of calcium channel blockers on ATP-binding cassette protein expression.
Topics: Atherosclerosis; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Calcium Channel Blockers; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dihydropyridines; Humans; Hypertension; Janus Kinase 2; Nitrophenols; Organophosphorus Compounds; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; RNA, Messenger | 2005 |
Determination of aranidipine and its active metabolite in human plasma by liquid chromatography/negative electrospray ionization tandem mass spectrometry.
Topics: Calcium Channel Blockers; Chromatography, High Pressure Liquid; Dihydropyridines; Humans; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2006 |