arachidonic-acid-omega-9-hydroperoxide and pyrazolanthrone
arachidonic-acid-omega-9-hydroperoxide has been researched along with pyrazolanthrone* in 1 studies
Other Studies
1 other study(ies) available for arachidonic-acid-omega-9-hydroperoxide and pyrazolanthrone
| Article | Year |
|---|---|
Baicalein inhibits matrix metalloproteinase 1 expression via activation of TRPV1-Ca-ERK pathway in ultraviolet B-irradiated human dermal fibroblasts.
Increased matrix metalloproteinase 1 (MMP-1) expression is a feature of photo-aged skin. We investigated the effects of baicalein and sulphoraphane on ultraviolet B (UVB) irradiation-induced MMP-1 expression and apoptosis using human dermal fibroblasts. UVB irradiation not only increased MMP-1 expression, but also caused apoptosis. Both baicalein and sulphoraphane protected cells from UVB irradiation-induced apoptosis, but only baicalein inhibited MMP-1 expression. UVB irradiation activated 12-lipoxygenase, and its product, 12-hydroxyeicosatetraenoic acid, activated TRPV1 channels. The resulting UVB irradiation-induced Ca Topics: Anthracenes; Antioxidants; Apoptosis; Arachidonate 12-Lipoxygenase; Calcium; Capsaicin; Cytosol; Dermis; Egtazic Acid; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Flavanones; Humans; Leukotrienes; Matrix Metalloproteinase 1; NF-E2-Related Factor 2; Phosphorylation; Reactive Oxygen Species; Signal Transduction; Skin; Skin Aging; TRPV Cation Channels; Ultraviolet Rays | 2019 |