Compounds > arachidonic acid 5-hydroperoxide

arachidonic acid 5-hydroperoxide and arachidonic acid

arachidonic acid 5-hydroperoxide has been researched along with arachidonic acid in 59 studies

Research

Studies (59)

TimeframeStudies, this research(%)All Research%
pre-199029 (49.15)18.7374
1990's24 (40.68)18.2507
2000's3 (5.08)29.6817
2010's2 (3.39)24.3611
2020's1 (1.69)2.80

Authors

AuthorsStudies
Harish, OE; Poo, MM1
Henson, PM; Hill, E; Maclouf, J; Murphy, RC1
Curtis, WR; Reddanna, P; Reddy, CC; Reddy, GR1
Farkas, T; Kuehn, H; Nemecz, G; Wallukat, G; Wollenberger, A1
Heydeck, D; Kühn, H; Schewe, T; Wiesner, R1
Ausiello, DA; Birnbaumer, L; Cantiello, HF; Codina, J; Patenaude, CR1
Leung, PC; Wang, J; Yuen, BH1
Choo, LY; Denis, D; Nathaniel, DJ; Riendeau, D1
Gut, J; Trudell, JR1
Hirai, A; Tahara, K; Tamura, Y; Terano, T; Yoshida, S1
Harrison, BL; Nichols, JS; Skoog, MT; Wiseman, JS2
Hatzelmann, A; Ullrich, V1
Reynolds, CH1
Brash, AR; Ingram, CD; Maas, RL; Oates, JA; Porter, AT; Taber, DF1
Hirai, A; Saito, H; Tahara, K; Tamura, Y; Terano, T; Yoshida, S1
Matsumoto, T; Rouzer, CA; Samuelsson, B1
Kragballe, K; Voorhees, JJ1
Izumi, T; Rådmark, O; Samuelsson, B; Seyama, Y; Shimizu, T; Tadokoro, K1
Puustinen, T; Samuelsson, B; Scheffer, MM1
Brahmi, Z; Bray, RA1
Lands, WE; Marshall, PJ1
Bryant, RW; Ng, KJ; She, HS; Siegel, MI1
Leblanc, Y; Riendeau, D1
Aharony, D; Hubbs, SJ; Redkar-Brown, DG; Stein, RL1
Reddanna, P; Reddy, CC; Reddy, PS; Whelan, J1
Colca, JR; McDaniel, ML; Turk, J1
Bornemeier, D; Bouska, J; Carter, GW; Fayer, L; Goetze, AM1
König, W; Raulf, M; Stüning, M1
Adams, GK; Adkinson, NF; Kagey-Sobotka, A; Lichtenstein, LM; MacGlashan, DW; Peters, SP; Schleimer, RP; Schulman, ES1
Brash, AR; Maas, RL; Oates, JA; Roberts, LJ; Turk, J1
Austen, KF; Lewis, RA1
Fukuyama, S; Hirano, T; Nagano, S; Takahashi, T1
Bonser, RW; Cuatrecasas, P; McConnell, RT; Siegel, MI1
Katori, M1
Fukui, Y; Hirota, R; Iizumi, H; Matsuoka, M; Morita, M; Nakayama, T; Osakada, K; Ueda, T1
Grigg, JJ; Koyano, K; Nakajima, S; Nakajima, Y; Velimirovic, BM1
Matsumoto, T; Miyano, M; Noguchi, M; Noma, M1
Henson, PM; Hill, E; MacMillan, DK; Murphy, RC; Sala, A; Shuman, T; Sigal, E1
Li, C; Mancini, JA; Vickers, PJ1
Chilton, FH; Hubbard, WC; Sung, CM; Winkler, JD1
Blair, IA; Christman, BW; Christman, JW; Dworski, R; Prakash, C1
Mirzoeva, OK; Pushkareva, MA; Sud'ina, GF; Varfolomeev, SD1
Brideau, C; Chan, CC; Chauret, N; Delorme, D; Desmarais, S; Dubé, D; Ducharme, Y; Falgueyret, JP; Fortin, R; Girard, Y; Guay, J; Hamel, P; Jones, TR; Lépine, C; Li, C; McAuliffe, M; McFarlane, CS; Nicoll-Griffith, DA; Riendeau, D; Yergey, JA1
Martin, GR; Reich, R1
Kiesel, L; Przylipiak, A; Przylipiak, J; Rabe, T; Runnebaum, B1
Arai, M; Chiba, N; Imai, H; Nakagawa, Y; Narashima, K; Sakamoto, H1
Horiuchi, M; Mita, S; Miyake, Y; Tsuji, F1
Battu, S; Beneytout, JL; Moalic, S; Rigaud, M1
van Zadelhoff, G; Veldink, GA; Vliegenthart, JF1
Hafezi, F; Munz, K; Reinboth, JJ; Remé, CE; Wenzel, A1
Qiao, N; Takahashi, Y; Takamatsu, H; Yoshimoto, T1
Bader, BW; Bankhurst, AD; Doshi, RN; Whalen, MM1
Reinhart, AJ; Stocco, DM; Walsh, LP; Wang, X1
Devery, R; Miller, A; Stanton, C1
Agarwal, S; Padma, AS; Prasad, TS; Reddanna, P; Reddy, DB1
Cooke, M; Cornejo Maciel, F; Di Cónsoli, H; Maloberti, P1
Barbour, SR; Hixon, MS; Holman, TR; Smyrniotis, CJ; Xia, Z1
Bu, W; Eckenhoff, RG; Okuno, T; Yokomizo, T; Yuki, K1

Reviews

3 review(s) available for arachidonic acid 5-hydroperoxide and arachidonic acid

ArticleYear
Studies with purified human basophils and mast cells.
    Monographs in allergy, 1983, Volume: 18

    Topics: Arachidonic Acid; Arachidonic Acids; Basophils; Cell Separation; Histamine; Histamine Release; Humans; Leukotrienes; Mast Cells; Peptide Hydrolases; Platelet Activating Factor; Prostaglandin D2; Prostaglandins D; Receptors, IgE; Receptors, Immunologic

1983
The biologically active leukotrienes. Biosynthesis, metabolism, receptors, functions, and pharmacology.
    The Journal of clinical investigation, 1984, Volume: 73, Issue:4

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Bronchial Spasm; Chemical Phenomena; Chemistry; Diethylcarbamazine; Guinea Pigs; Humans; Inflammation; Leukotrienes; Lipoxygenase; Mast Cells; Mice; Monocytes; Muscle, Smooth; Rats; Receptors, Cell Surface; Receptors, Leukotriene; SRS-A

1984
[Recent progress in the studies of prostaglandins--new arachidonic acid metabolites and inhibitors].
    Nihon rinsho. Japanese journal of clinical medicine, 1982, Volume: 40, Issue:1

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cricetinae; Dinoprost; Dinoprostone; Guinea Pigs; Humans; Leukotrienes; Muscle Contraction; Muscle, Smooth; Phospholipases; Platelet Aggregation; Prostaglandins E; Prostaglandins F; Rabbits; SRS-A; Thromboxane A2

1982

Other Studies

56 other study(ies) available for arachidonic acid 5-hydroperoxide and arachidonic acid

ArticleYear
Retrograde modulation at developing neuromuscular synapses: involvement of G protein and arachidonic acid cascade.
    Neuron, 1992, Volume: 9, Issue:6

    Topics: Acetylcholine; Animals; Arachidonic Acid; Benzoquinones; Cyclic AMP; Diglycerides; Electric Conductivity; Embryo, Nonmammalian; Guanosine Triphosphate; Leukotrienes; Neuromuscular Junction; Organ Culture Techniques; Synapses; Xenopus

1992
Reversible membrane association of neutrophil 5-lipoxygenase is accompanied by retention of activity and a change in substrate specificity.
    The Journal of biological chemistry, 1992, Nov-05, Volume: 267, Issue:31

    Topics: Arachidonate 5-Lipoxygenase; Arachidonic Acid; Calcimycin; Cell Compartmentation; Cell Membrane; Cytosol; Humans; Hydroxyeicosatetraenoic Acids; Hydroxyurea; In Vitro Techniques; Indoles; Leukotrienes; Neutrophils; Substrate Specificity

1992
11-hydroperoxyeicosatetraenoic acid is the major dioxygenation product of lipoxygenase isolated from hairy root cultures of Solanum tuberosum.
    Biochemical and biophysical research communications, 1992, Dec-30, Volume: 189, Issue:3

    Topics: Arachidonic Acid; Cells, Cultured; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Kinetics; Leukotrienes; Lipoxygenase; Oxygen; Solanum tuberosum

1992
Modulation of the beta-adrenergic response in cultured rat heart cells. I. Beta-adrenergic supersensitivity is induced by lactate via a phospholipase A2 and 15-lipoxygenase involving pathway.
    Molecular and cellular biochemistry, 1991, Mar-27, Volume: 102, Issue:1

    Topics: Acetophenones; Animals; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Chronobiology Phenomena; Dose-Response Relationship, Drug; Enzyme Activation; Heart; Hydroxyeicosatetraenoic Acids; Isoproterenol; Lactates; Leukotrienes; Melitten; Phospholipases A; Phospholipases A2; Prostaglandins D; Quinacrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta

1991
On the reaction of wheat lipoxygenase with arachidonic acid and its oxygenated derivatives.
    Biomedica biochimica acta, 1991, Volume: 50, Issue:1

    Topics: Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arachidonic Acids; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Hydroxyeicosatetraenoic Acids; Leukotrienes; Linoleic Acid; Linoleic Acids; Lipoxygenase; Spectrophotometry, Ultraviolet; Triticum

1991
G alpha i-3 regulates epithelial Na+ channels by activation of phospholipase A2 and lipoxygenase pathways.
    The Journal of biological chemistry, 1990, Dec-15, Volume: 265, Issue:35

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cell Compartmentation; Cell Line; Cell Membrane; Enzyme Activation; Epithelium; GTP-Binding Proteins; In Vitro Techniques; Kidney; Leukotrienes; Lipoxygenase; Masoprocol; Melitten; Pertussis Toxin; Phospholipases A; Phospholipases A2; Quinacrine; Signal Transduction; Sodium Channels; SRS-A; Virulence Factors, Bordetella; Xenopus

1990
Stimulation of progesterone and prostaglandin E2 production by lipoxygenase metabolites of arachidonic acid.
    FEBS letters, 1989, Feb-13, Volume: 244, Issue:1

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Dinoprostone; Drug Interactions; Female; Gonadotropin-Releasing Hormone; Granulosa Cells; Hydroxyeicosatetraenoic Acids; Leukotrienes; Lipid Peroxides; Lipoxygenase; Progesterone; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate

1989
Stimulation of 5-lipoxygenase activity under conditions which promote lipid peroxidation.
    The Biochemical journal, 1989, Oct-15, Volume: 263, Issue:2

    Topics: Adenosine Triphosphate; Animals; Arachidonate 5-Lipoxygenase; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Calcium; Enzyme Activation; Ferric Compounds; Ferrous Compounds; Flavin-Adenine Dinucleotide; Hydrogen Peroxide; Hydroxyeicosatetraenoic Acids; Leukotrienes; Lipid Peroxidation; Lipoxygenase Inhibitors; Mercaptoethanol; NAD; NADP; Rats

1989
Properties of enzymes in hepatocytes that convert 5-HPETE or LTA4 into LTB4.
    Free radical biology & medicine, 1989, Volume: 7, Issue:3

    Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arachidonic Acids; Binding Sites; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Endoplasmic Reticulum; Free Radicals; Leukotriene A4; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Liver; Male; Models, Biological; Molecular Structure; Oxygen; Rats; Rats, Inbred F344

1989
Role of 5-lipoxygenase (5-LO) metabolites in ACTH-stimulated steroidogenesis.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1987, Volume: 17B

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Arachidonate 5-Lipoxygenase; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Cyclic AMP; In Vitro Techniques; Leukotrienes; Lipoxygenase Inhibitors; Rats; Steroids

1987
Kinetics of leukotriene A4 synthesis by 5-lipoxygenase from rat polymorphonuclear leukocytes.
    Biochemistry, 1987, Sep-08, Volume: 26, Issue:18

    Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Kinetics; Leukotriene A4; Leukotrienes; Neutrophils; Rats; Tritium

1987
Regulation of 5-lipoxygenase activity by the glutathione status in human polymorphonuclear leukocytes.
    European journal of biochemistry, 1987, Nov-16, Volume: 169, Issue:1

    Topics: Adult; Arachidonate 5-Lipoxygenase; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Chromatography, High Pressure Liquid; Diamide; Dinitrochlorobenzene; Glutathione; Humans; Hydroxyeicosatetraenoic Acids; Kinetics; Leukotriene B4; Leukotrienes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils

1987
5-Lipoxygenase and leukotriene synthesis: effects of calcium ions and of inhibitors.
    Prostaglandins, 1988, Volume: 36, Issue:1

    Topics: Arachidonate 5-Lipoxygenase; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Calcium; Humans; Hydrogen-Ion Concentration; Leukotriene B4; Leukotrienes

1988
Investigation of the chemical conversion of hydroperoxyeicosatetraenoate to leukotriene epoxide using stereospecifically labeled arachidonic acid. Comparison with the enzymatic reaction.
    The Journal of biological chemistry, 1985, Apr-10, Volume: 260, Issue:7

    Topics: Arachidonic Acid; Arachidonic Acids; Chemical Phenomena; Chemistry, Physical; Chromatography, High Pressure Liquid; Hydrogen; Leukotriene A4; Leukotrienes; Lipid Peroxides; Magnetic Resonance Spectroscopy; Spectrophotometry, Ultraviolet; Stereoisomerism

1985
Involvement of 5-lipoxygenase metabolites in ACTH-stimulated corticosteroidogenesis in rat adrenal glands.
    Prostaglandins, 1985, Volume: 30, Issue:5

    Topics: Adrenal Cortex; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Benzoquinones; Cyclic AMP; Dose-Response Relationship, Drug; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Indomethacin; Leukotriene B4; Leukotrienes; Lipoxygenase; Male; Quinones; Rats; Rats, Inbred Strains

1985
Single protein from human leukocytes possesses 5-lipoxygenase and leukotriene A4 synthase activities.
    Proceedings of the National Academy of Sciences of the United States of America, 1986, Volume: 83, Issue:4

    Topics: Adenosine Triphosphate; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Calcium; Chromatography, Affinity; Chromatography, Gel; Chromatography, High Pressure Liquid; Humans; Leukocytes; Leukotriene A4; Leukotrienes; Lipoxygenase

1986
Arachidonic acid in psoriasis. Pathogenic role and pharmacological regulation.
    Acta dermato-venereologica. Supplementum, 1985, Volume: 120

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Arachidonic Acid; Arachidonic Acids; Fish Oils; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Leukotrienes; Lipoxygenase; Lipoxygenase Inhibitors; Psoriasis; Skin; SRS-A

1985
Characterization of leukotriene A4 synthase from murine mast cells: evidence for its identity to arachidonate 5-lipoxygenase.
    Proceedings of the National Academy of Sciences of the United States of America, 1986, Volume: 83, Issue:12

    Topics: Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Cell Line; Hot Temperature; Leukotriene B4; Leukotrienes; Lipoxygenase; Mast Cells; Mice

1986
Endogenously generated 5-hydroperoxyeicosatetraenoic acid is the preferred substrate for human leukocyte leukotriene A4 synthase activity.
    FEBS letters, 1987, Jun-15, Volume: 217, Issue:2

    Topics: Arachidonate 5-Lipoxygenase; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Humans; Leukocytes; Leukotriene A4; Leukotrienes; Substrate Specificity

1987
Role of lipoxygenation in human natural killer cell activation.
    Journal of immunology (Baltimore, Md. : 1950), 1986, Mar-01, Volume: 136, Issue:5

    Topics: Arachidonic Acid; Arachidonic Acids; Cytotoxicity, Immunologic; Diethylcarbamazine; Epoprostenol; Humans; Immunosuppressive Agents; Killer Cells, Natural; Kinetics; Leukotrienes; Lipoxygenase; Lipoxygenase Inhibitors; Lymphocyte Activation

1986
Glutathione peroxidase is neither required nor kinetically competent for conversion of 5-HPETE to 5-HETE in rat PMN lysates.
    Prostaglandins, 1986, Volume: 31, Issue:3

    Topics: Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Cell-Free System; Glutathione; Glutathione Peroxidase; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Kinetics; Leukotrienes; Lipoxygenase; Neutrophils; Oxidation-Reduction; Peroxidases; Rats; Thiomalates

1986
In vitro formation of activators for prostaglandin synthesis by neutrophils and macrophages from humans and guinea pigs.
    The Journal of laboratory and clinical medicine, 1986, Volume: 108, Issue:6

    Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Catalase; Enzyme Activation; Glutathione Peroxidase; Guinea Pigs; HEPES; Humans; Hydrogen Peroxide; Leukotrienes; Macrophages; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Tetradecanoylphorbol Acetate; Zymosan

1986
Modulation of the 5-lipoxygenase activity of MC-9 mast cells: activation by hydroperoxides.
    Prostaglandins, 1986, Volume: 32, Issue:4

    Topics: Adenosine Triphosphate; Animals; Arachidonate 5-Lipoxygenase; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Calcium; Clone Cells; Cytosol; Enzyme Activation; Glutathione; Leukotrienes; Mast Cells; Mice

1986
Modulation of rat polymorphonuclear leukocyte 5-lipoxygenase activity by 5-HPETE and NADH-dependent flavin inhibition.
    Biochemical and biophysical research communications, 1986, Dec-15, Volume: 141, Issue:2

    Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Cell Compartmentation; Enzyme Activation; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Leukotrienes; Male; NAD; NADP; Neutrophils; Rats

1986
Kinetic studies on the inactivation of 5-lipoxygenase by 5(S)-hydroperoxyeicosatetraenoic acid.
    Prostaglandins, 1987, Volume: 33, Issue:1

    Topics: Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Dithiothreitol; Guinea Pigs; In Vitro Techniques; Kinetics; Leukotrienes; Lipoxygenase Inhibitors; Neutrophils; Oxidation-Reduction; Sulfhydryl Compounds

1987
Isolation and characterization of 5-lipoxygenase from tulip bulbs.
    Biochemical and biophysical research communications, 1988, Dec-30, Volume: 157, Issue:3

    Topics: Arachidonate 5-Lipoxygenase; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Blotting, Western; Chromatography, High Pressure Liquid; Cytosol; Isoelectric Point; Kinetics; Leukotrienes; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Weight; Nuclear Envelope; Oxygen; Plants; Species Specificity

1988
Arachidonic acid metabolism in isolated pancreatic islets. III. Effects of exogenous lipoxygenase products and inhibitors on insulin secretion.
    Biochimica et biophysica acta, 1985, Mar-27, Volume: 834, Issue:1

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Gas Chromatography-Mass Spectrometry; Hydroxyeicosatetraenoic Acids; Insulin; Insulin Secretion; Islets of Langerhans; Leukotrienes; Lipoxygenase; Male; Pyrazoles; Rats; Rats, Inbred Strains

1985
Purification of a mammalian 5-lipoxygenase from rat basophilic leukemia cells.
    Prostaglandins, 1985, Volume: 29, Issue:5

    Topics: Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Basophils; Chromatography, Gel; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Leukemia; Leukotrienes; Lipoxygenase; Rats; Time Factors

1985
Localization of 5-lipoxygenase within human polymorphonuclear leukocytes.
    Biochemical pharmacology, 1985, Nov-15, Volume: 34, Issue:22

    Topics: Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Calcimycin; Carbon Radioisotopes; Cytoplasmic Granules; Humans; Leukotrienes; Lipoxygenase; Neutrophils; Serum Albumin, Bovine

1985
Conjugated triene metabolites of arachidonic acid derived from dioxygenation at carbon-15: origin from eosinophil and mechanisms of biosynthesis.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1983, Volume: 11

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Chromatography, High Pressure Liquid; Eosinophils; Humans; Leukotrienes; Lipid Peroxides; Mice; Oxidation-Reduction; Species Specificity; Swine

1983
The effect of exogenous arachidonic acid on insulin secretion in isolated perifused hamster islets.
    Endocrinologia japonica, 1984, Volume: 31, Issue:5

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Catechols; Cricetinae; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Leukotrienes; Lipoxygenase; Male; Masoprocol; Mesocricetus; Perfusion; Prostaglandins E; Sodium Salicylate

1984
The lipoxygenase product, 5-hydroperoxy-arachidonic acid, augments chemotactic peptide-stimulated arachidonic acid release from HL60 granulocytes.
    Biochemical and biophysical research communications, 1982, Feb-11, Volume: 104, Issue:3

    Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Cell Line; Chemotaxis, Leukocyte; Granulocytes; Humans; Leukemia, Myeloid; Leukotrienes; Oligopeptides

1982
Visible light-sensitized oxidation of arachidonic acid in the presence of inperatorin.
    Journal of nutritional science and vitaminology, 1995, Volume: 41, Issue:3

    Topics: Arachidonic Acid; beta Carotene; Borohydrides; Carotenoids; Chromatography, High Pressure Liquid; Furocoumarins; Gas Chromatography-Mass Spectrometry; Leukotrienes; Light; Lipid Peroxides; Mannitol; Oxidation-Reduction; Photochemistry; Photosensitizing Agents; Reactive Oxygen Species; Superoxide Dismutase

1995
The role of arachidonic acid metabolism in somatostatin and substance P effects on inward rectifier K conductance in rat brain neurons.
    Neuroscience research, 1994, Volume: 20, Issue:4

    Topics: Animals; Arachidonic Acid; Brain; Electric Conductivity; Leukotrienes; Locus Coeruleus; Neurons; Potassium; Prosencephalon; Rats; Rats, Inbred Strains; Somatostatin; Substance P

1994
Human 5-lipoxygenase associates with phosphatidylcholine liposomes and modulates LTA4 synthetase activity.
    Biochimica et biophysica acta, 1994, Dec-08, Volume: 1215, Issue:3

    Topics: Adenosine Triphosphate; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Calcium; Enzyme Activation; Humans; Leukotriene A4; Leukotrienes; Liposomes; Phosphatidylcholines

1994
Eosinophil 15-lipoxygenase is a leukotriene A4 synthase.
    The Journal of biological chemistry, 1994, Oct-28, Volume: 269, Issue:43

    Topics: Arachidonate 15-Lipoxygenase; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Cell-Free System; Cytosol; Dose-Response Relationship, Drug; Eosinophils; Granulocytes; Humans; Hydroxyeicosatetraenoic Acids; Hydroxyurea; Leukotriene A4; Leukotrienes; Lipoxygenase Inhibitors; Models, Chemical; Neutrophils; Recombinant Proteins

1994
5-Lipoxygenase activity in the human pancreas.
    Journal of lipid mediators, 1993, Volume: 8, Issue:3

    Topics: 5-Lipoxygenase-Activating Proteins; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Blotting, Western; Carrier Proteins; Chromatography, High Pressure Liquid; Female; Humans; Leukotriene A4; Leukotriene B4; Leukotrienes; Male; Membrane Proteins; Middle Aged; Pancreas; Subcellular Fractions

1993
Influence of arachidonic acid on indices of phospholipase A2 activity in the human neutrophil.
    The Biochemical journal, 1993, May-01, Volume: 291 ( Pt 3)

    Topics: Arachidonic Acid; Calcimycin; Fatty Acids; Fatty Acids, Nonesterified; Gas Chromatography-Mass Spectrometry; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Leukotrienes; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor

1993
Prostaglandin E2 limits arachidonic acid availability and inhibits leukotriene B4 synthesis in rat alveolar macrophages by a nonphospholipase A2 mechanism.
    Journal of immunology (Baltimore, Md. : 1950), 1993, Aug-15, Volume: 151, Issue:4

    Topics: Animals; Arachidonic Acid; Calcimycin; Dinoprostone; Leukotriene B4; Leukotrienes; Macrophages, Alveolar; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Rats

1993
Competitive inhibition of the 5-lipoxygenase-catalysed linoleate oxidation by arachidonic and 5-hydroperoxy-eicosatetraenoic acids.
    FEBS letters, 1995, Dec-27, Volume: 377, Issue:3

    Topics: Arachidonic Acid; Enzyme Activation; Hordeum; Hydrogen-Ion Concentration; Leukotrienes; Linoleic Acid; Linoleic Acids; Lipoxygenase Inhibitors; Substrate Specificity

1995
Dioxabicyclooctanyl naphthalenenitriles as nonredox 5-lipoxygenase inhibitors: structure-activity relationship study directed toward the improvement of metabolic stability.
    Journal of medicinal chemistry, 1996, Sep-27, Volume: 39, Issue:20

    Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Benzofurans; Bronchoconstriction; Drug Stability; Humans; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Male; Microsomes, Liver; Molecular Structure; Naphthalenes; Neutrophils; Nitriles; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Saimiri; Structure-Activity Relationship

1996
Identification of arachidonic acid pathways required for the invasive and metastatic activity of malignant tumor cells.
    Prostaglandins, 1996, Volume: 51, Issue:1

    Topics: Animals; Arachidonic Acid; Caffeine; Collagen; Cyclooxygenase Inhibitors; Dinoprost; Drug Combinations; Extracellular Matrix; Fibrosarcoma; Gelatinases; Humans; Indoles; Indomethacin; Laminin; Leukotrienes; Lipoxygenase Inhibitors; Masoprocol; Matrix Metalloproteinase 2; Melanoma; Metalloendopeptidases; Mice; Neoplasm Metastasis; Proteoglycans; Tumor Cells, Cultured; Umbelliferones

1996
Inhibitory effect of leukotrienes on luteinizing hormone release.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 1997, Volume: 11, Issue:3

    Topics: Animals; Arachidonic Acid; Cells, Cultured; Female; Gonadotropin-Releasing Hormone; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Leukotriene C4; Leukotriene D4; Leukotriene E4; Leukotrienes; Luteinizing Hormone; Perfusion; Pituitary Gland, Anterior; Rats; Rats, Sprague-Dawley; Time Factors

1997
Suppression of leukotriene formation in RBL-2H3 cells that overexpressed phospholipid hydroperoxide glutathione peroxidase.
    The Journal of biological chemistry, 1998, Jan-23, Volume: 273, Issue:4

    Topics: Animals; Antioxidants; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Calcimycin; Cell Line; Cell Separation; Chromatography, High Pressure Liquid; Flow Cytometry; Glutathione Peroxidase; Hydroxyeicosatetraenoic Acids; Ionophores; Leukotrienes; Phospholipid Hydroperoxide Glutathione Peroxidase; Proteins; Rats; Selenoproteins

1998
Involvement of leukotriene B4 in murine dermatitis models.
    Biochemical pharmacology, 1998, Feb-01, Volume: 55, Issue:3

    Topics: Aniline Compounds; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Cysteine; Dermatitis; Enzyme Inhibitors; Epoxide Hydrolases; Leukotriene B4; Leukotrienes; Male; Mice; Mice, Inbred ICR

1998
Linoleic acid peroxidation by Solanum tuberosum lipoxygenase was activated in the presence of human 5-lipoxygenase-activating protein.
    Biochimica et biophysica acta, 1998, Jun-15, Volume: 1392, Issue:2-3

    Topics: 5-Lipoxygenase-Activating Proteins; Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Baculoviridae; Calcium; Carrier Proteins; Cell Membrane; Enzyme Activation; Humans; Indoles; Leukotrienes; Linoleic Acid; Linoleic Acids; Lipoxygenase Inhibitors; Membrane Proteins; Oxidation-Reduction; Recombinant Proteins; Solanum tuberosum; Spodoptera; Transfection

1998
With anandamide as substrate plant 5-lipoxygenases behave like 11-lipoxygenases.
    Biochemical and biophysical research communications, 1998, Jul-09, Volume: 248, Issue:1

    Topics: Arachidonate 5-Lipoxygenase; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Endocannabinoids; Ethanolamines; Fatty Acids, Unsaturated; Glycine max; Hordeum; Leukotrienes; Plants; Polyunsaturated Alkamides; Solanum lycopersicum; Substrate Specificity

1998
[HPETE, an arachidonic acid metabolite, induces apoptosis in rat retina in vitro].
    Klinische Monatsblatter fur Augenheilkunde, 1998, Volume: 212, Issue:6

    Topics: Animals; Apoptosis; Arachidonic Acid; In Vitro Techniques; Leukotrienes; Microscopy, Electron; Pilot Projects; Rats; Retina

1998
Leukotriene A synthase activity of purified mouse skin arachidonate 8-lipoxygenase expressed in Escherichia coli.
    Biochimica et biophysica acta, 1999, Apr-19, Volume: 1438, Issue:1

    Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonate Lipoxygenases; Arachidonic Acid; Cloning, Molecular; DNA, Complementary; Escherichia coli; Gene Expression; Leukotrienes; Mice; Skin; Substrate Specificity

1999
Lysophosphatidylcholine and arachidonic acid are required in the cytotoxic response of human natural killer cells to tumor target cells.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 1999, Volume: 9, Issue:6

    Topics: Acetophenones; Arachidonic Acid; Cytotoxicity, Immunologic; Enzyme Inhibitors; Humans; K562 Cells; Killer Cells, Natural; Leukotrienes; Linoleic Acid; Lipid Peroxides; Lysophosphatidylcholines; Phospholipases A; Quinacrine

1999
The role of arachidonic acid in steroidogenesis and steroidogenic acute regulatory (StAR) gene and protein expression.
    The Journal of biological chemistry, 2000, Jun-30, Volume: 275, Issue:26

    Topics: Animals; Arachidonic Acid; Benzoquinones; Blotting, Northern; Blotting, Western; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dexamethasone; Gene Expression; Glucocorticoids; Leukotrienes; Lipoxygenase Inhibitors; Luciferases; Mice; Phospholipases A; Phosphoproteins; Phosphorylation; Progesterone; Promoter Regions, Genetic; Signal Transduction; Steroids; Transcription, Genetic; Transfection; Tumor Cells, Cultured

2000
Modulation of arachidonic acid distribution by conjugated linoleic acid isomers and linoleic acid in MCF-7 and SW480 cancer cells.
    Lipids, 2001, Volume: 36, Issue:10

    Topics: Arachidonic Acid; Breast Neoplasms; Carbon Radioisotopes; Cell Survival; Colonic Neoplasms; Dinoprost; Dinoprostone; Humans; Leukotriene B4; Leukotrienes; Linoleic Acid; Prostaglandin D2; Tumor Cells, Cultured

2001
Metabolism of arachidonic acid in sheep uterus: in vitro studies.
    Indian journal of biochemistry & biophysics, 2007, Volume: 44, Issue:4

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Dinoprost; Female; Hydroxyeicosatetraenoic Acids; Leukotrienes; Lipoxygenase; Prostaglandin-Endoperoxide Synthases; Sheep; Uterus

2007
Expression and function of OXE receptor, an eicosanoid receptor, in steroidogenic cells.
    Molecular and cellular endocrinology, 2013, May-22, Volume: 371, Issue:1-2

    Topics: Adrenal Cortex; Animals; Arachidonic Acid; Arachidonic Acids; Cell Line; Docosahexaenoic Acids; Gene Expression; Humans; Leukotrienes; Leydig Cells; Male; Mice; Phosphoproteins; Receptors, Eicosanoid; RNA, Messenger; Steroids; Transcription, Genetic

2013
ATP allosterically activates the human 5-lipoxygenase molecular mechanism of arachidonic acid and 5(S)-hydroperoxy-6(E),8(Z),11(Z),14(Z)-eicosatetraenoic acid.
    Biochemistry, 2014, Jul-15, Volume: 53, Issue:27

    Topics: Adenosine Triphosphate; Allosteric Regulation; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Calcium; Enzyme Activation; Epoxy Compounds; Humans; Leukotriene A4; Leukotrienes; Peroxides; Stereoisomerism; Viscosity

2014
The role of propofol hydroxyl group in 5-lipoxygenase recognition.
    Biochemical and biophysical research communications, 2020, 05-14, Volume: 525, Issue:4

    Topics: Anesthetics, Intravenous; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Binding Sites; Calcimycin; Calcium Ionophores; HEK293 Cells; Humans; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Molecular Docking Simulation; Mutagenesis; Propofol; Protein Conformation; Structure-Activity Relationship

2020