arabinofuranosyluracil has been researched along with uridine in 83 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 72 (86.75) | 18.7374 |
| 1990's | 6 (7.23) | 18.2507 |
| 2000's | 2 (2.41) | 29.6817 |
| 2010's | 2 (2.41) | 24.3611 |
| 2020's | 1 (1.20) | 2.80 |
| Authors | Studies |
|---|---|
| Guinan, M; Huang, N; Miller, GJ; Smith, M | 1 |
| Bhooshan, B; De Clercq, E; Descamps, J; Edwards, MW; Huang, GF; Torrence, PF | 1 |
| De Clercq, E; Descamps, J; Kulikowski, T; Shugar, D; Zawadzki, Z | 1 |
| Müller, WE; Zahn, RK | 1 |
| Kuninaka, A; Machida, H; Nakayama, C; Sakata, S; Saneyoshi, M; Yoshino, H | 1 |
| Dalton, JG; George, AL; Hruska, FE; McGaig, TN; Ogilvie, KK; Pelling, J; Wood, DJ | 1 |
| Machida, H; Takezawa, J | 1 |
| Machida, H; Nishitani, M | 1 |
| Chou, TC; Fox, JJ; Gloff, CA; Soike, KF; Watanabe, KA | 1 |
| Novotný, L; Vachálková, A | 1 |
| Chomel, B; Fourel, I; Fox, JJ; Hantz, O; Jacquet, C; Trepo, C; Watanabe, KA | 1 |
| Konno, K; Kumagai, M; Machida, H; Mori, S; Shigeta, S; Watanabe, Y; Yokota, T | 1 |
| Sougawa, M; Tanaka, Y | 1 |
| Lasorella, A; Riccardi, A; Riccardi, R; Servidei, T | 1 |
| Capizzi, RL; Chandrasekaran, B; Dimling, J; Kute, TE; Morgan, T | 1 |
| Hassan, FM; Pesce, AJ; Pruemer, JM; Warner, A; Wermeling, JR | 1 |
| Cheng, YC; Chou, TC; Fanucchi, MP; Fox, JJ; Kong, XB; Takahashi, K; Watanabe, KA | 1 |
| Gadler, H; Nawrot, B; Pankiewicz, KW; Price, RW; Watanabe, KA | 1 |
| Gadler, H; Huang, JT; Price, RW; Schinazi, RF; Su, TL; Watanabe, KA | 1 |
| Cech, D; Pein, CD; Reefschläger, J | 1 |
| Chou, TC; Gadler, H; Kalman, TI; Matulic-Adamic, J; Price, RW; Reddy, AR; Takahashi, K; Watanabe, KA | 1 |
| Borrelli, E; Evans, RM; Heyman, R; Hsi, M | 1 |
| Azuma, M; Machida, H; Sakuma, T; Suzutani, T | 1 |
| Lin, JC; Machida, H | 1 |
| Herrmann, G; Reefschläger, J; Thiel, KD; Wutzler, P | 2 |
| Engle, KK; Higuchi, T; Liversidge, GG; Nishihata, T | 1 |
| Färber, I; Herrmann, G; Klinger, C; Reefschläger, J; Thiel, KD; Wutzler, P | 1 |
| Rajcáni, J; Reefschläger, J | 1 |
| Hsiung, GD; Landry, ML; Mayo, DR; Zheng, ZM | 1 |
| Burchenal, JH; Fanucchi, MP; Fox, JJ; Leyland-Jones, B; Watanabe, KA; Young, CW | 1 |
| Nakayama, C; Nishiyama, Y; Saneyoshi, M; Suzuki, S; Yoshida, S | 1 |
| Fox, JJ; Harada, K; Matulic-Adamic, J; Price, RW; Schinazi, RF; Watanabe, KA | 1 |
| Knaus, EE; Misra, HK; Suzuki, S; Tyrrell, DL; Wiebe, LI | 1 |
| Benigni, DA; Brodfuehrer, PR; Chen, MS; Ghazzouli, I; Howell, HG; Mansuri, MM; Martin, JC | 1 |
| Machida, H; Saneyoshi, M; Suzuki, S | 1 |
| Gill, MJ; Knaus, EE; Misra, HK; Samuel, J; Tovell, DR; Tyrrell, DL; Wiebe, LI; Yacyshyn, HP | 1 |
| Banerjee, A; Biswas, G; Duax, WL; Shugar, D | 1 |
| Pankiewicz, KW; Watanabe, KA | 1 |
| Muus, P; Punt, K; Roelofs, JM; van Prooijen, HC | 1 |
| Ayisi, NK; De Clercq, E; Machida, H; Sacks, SL; Wall, RA; Wanklin, RJ | 1 |
| De Clercq, E; Groen, J; Osterhaus, AD | 1 |
| Avramis, VI; Powell, W | 1 |
| Cantrell, C; Gerone, PJ; Soike, KF | 1 |
| Colly, LP; Edelbroek, PM; Honders, W; vd Hoorn, F; Willemze, R | 1 |
| Sapse, AM; Snyder, G | 1 |
| Capizzi, RL; Cheng, EH; Cheng, YC; Kute, T; Yang, JL | 1 |
| Machida, H; Sakata, S | 1 |
| Baskin, G; Cantrell, C; Gerone, P; Soike, KF | 1 |
| Agarwal, RP; Lopez, JA | 1 |
| Matsukage, A; Nakayama, C; Ogasawara, M; Ohashi, A; Ono, K; Saneyoshi, M; Takahashi, T | 1 |
| Hsiung, GD; Mayo, DR | 1 |
| Ikeda, K; Kuninaka, A; Machida, H; Mizuno, Y; Yoshino, H | 1 |
| Kuninaka, A; Machida, H; Sakata, S; Yoshino, H | 1 |
| Alenius, S; Gotthammar, B; Johansson, NG; Larsson, A; Oberg, B; Stening, G | 1 |
| Chou, TC; Feinberg, A; Fox, JJ; Philips, FS; Su, TL; Vidal, PM; Watanabe, KA | 1 |
| Cheng, YC; Lin, JC; Pagano, JS; Smith, MC | 1 |
| Fox, JJ; Lopez, C; Nesburn, AB; Su, TL; Trousdale, MD; Watanabe, KA | 1 |
| Bärwolff, D; Cech, D; Herrmann, G; Langen, P; Reefschläger, J; Schwarz, B | 1 |
| Fox, JJ; Greenberg, N; Lopez, C; Reichman, U; Su, TL; Watanabe, KA | 1 |
| Sakuma, T | 1 |
| Kodama, K; Kuninaka, A; Morozumi, M; Sato, T; Yoshino, H | 1 |
| De Clercq, E; Kulikowski, T; Shugar, D; Zawadzki, Z | 1 |
| Knaus, EE; Lee, YW; Mercer, JR; Wiebe, LI | 2 |
| Evans, WE; Sinkule, JA | 1 |
| Nahmias, AJ; Peters, J; Schinazi, RF; Sokol, MK | 1 |
| Cortese, M; Higuchi, T; Liversidge, GG; Nishihata, T; Shaffer, R | 1 |
| Bjornsson, T; Capizzi, RL; Cheng, E; Cheng, YC; Sahasrabudhe, D; Tan, RS; Yang, JL | 1 |
| Fox, JJ; Last-Barney, K; Merluzzi, VJ | 1 |
| Fox, JJ; Price, RW; Rubenstein, R; Saito, Y; Watanabe, KA | 1 |
| Coderre, JA; Fox, JJ; Matsuda, A; Santi, DV; Watanabe, KA | 1 |
| Marquardt, H; Westendorf, J | 1 |
| Hirobe, M; Makino, Y; Matsubara, Y; Watanabe, K | 1 |
| Braun, TJ; Burchenal, JH; Chou, TC; Fox, JJ; Philips, FS; Schmid, FA; Su, TL; Watanabe, KA | 1 |
| Fox, JJ; Philips, FS; Price, RW; Rottenberg, DA; Saito, Y; Su, TL; Watanabe, KA | 1 |
| Drenthe-Schonk, A; Haanen, C; Linssen, P; Wessels, H | 1 |
| Breithaupt, H; Schick, J | 1 |
| Ashida, N; Kano, F; Machida, H; Miura, S; Sakata, S; Suzutani, T; Watanabe, Y; Yamaguchi, T | 1 |
| Fujibayashi, Y; Haraguchi, K; Hayashi, A; Sato, M; Tanaka, H; Toyohara, J; Yonekura, Y; Yoshimura, Y | 1 |
| Dittmar, K; Heiss, WD; Jacob, AJ; Jacobs, AH; Knaus, EE; Li, HF; Moharram, S; Stöckle, M; Wiebe, LI; Winkeler, A | 1 |
| Goltz, D; Jauch, C; Schott, H; Schott, TC; Schwendener, RA | 1 |
| Fu, Y; He, YX; Hou, HX; Li, HL; Wu, C; Xian, FY; Zhu, WB | 1 |
83 other study(ies) available for arabinofuranosyluracil and uridine
| Article | Year |
|---|---|
Design, chemical synthesis and antiviral evaluation of 2'-deoxy-2'-fluoro-2'-C-methyl-4'-thionucleosides.
Topics: Antiviral Agents; Dose-Response Relationship, Drug; Drug Design; Hepacivirus; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Thionucleosides; Virus Replication | 2022 |
5-Substituted uracil arabinonucleosides as potential antiviral agents.
Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Cells, Cultured; Chemical Phenomena; Chemistry; Humans; Rabbits; Simplexvirus; Structure-Activity Relationship; Uridine; Vaccinia virus | 1979 |
Synthesis and antiviral activities of arabinofuranosyl-5-ethylpyrimidine nucleosides. Selective antiherpes activity of 1-(beta-D-arabinofuranosyl)-5-ethyluracil.
Topics: Antiviral Agents; Arabinofuranosyluracil; Circular Dichroism; Cytarabine; Cytopathogenic Effect, Viral; Deamination; Magnetic Resonance Spectroscopy; Simplexvirus; Uridine; Vaccinia virus; Vesicular stomatitis Indiana virus | 1979 |
Metabolism of 1-beta-D-arabinofuranosyluracil in mouse L5178Y cells.
Topics: Animals; Arabinofuranosyluracil; Arabinonucleosides; Cell Division; Cells, Cultured; DNA, Neoplasm; Lymphoma; Mice; Neoplasms, Experimental; Nucleic Acid Synthesis Inhibitors; Phosphorylation; Uridine | 1979 |
In vitro antiherpesviral activity of 5-alkyl derivatives of 1-beta-D-arabinofuranosyluracil.
Topics: Arabinofuranosyluracil; Cell Division; Cytopathogenic Effect, Viral; DNA; Herpes Simplex; Thymidine; Uridine | 1979 |
Comparison of arabinose and ribose nucleoside conformation in aqueous and dimethylsulfoxide solution. 2',5'-Hydrogen bonding in arabinonucleosides.
Topics: Adenosine; Arabinofuranosyluracil; Arabinose; Dimethyl Sulfoxide; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Molecular Conformation; Ribonucleosides; Structure-Activity Relationship; Uridine; Vidarabine | 1977 |
Effect of 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil (brovavir) on experimental infections in mice with herpes simplex virus type 1 strains of different degrees of virulence.
Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Brain; Encephalitis; Herpes Simplex; Male; Mice; Mice, Inbred ICR; Simplexvirus; Uridine; Virus Replication | 1990 |
Drug susceptibilities of isolates of varicella-zoster virus in a clinical study of oral brovavir.
Topics: Acyclovir; Adult; Antiviral Agents; Arabinofuranosyluracil; Cell Line; Herpes Zoster; Herpesvirus 3, Human; Humans; Uridine | 1990 |
Inhibition of simian varicella virus infection of monkeys by 1-(2-deoxy-2- fluoro-1-beta-D-arabinofuranosyl)-5-ethyluracil (FEAU) and synergistic effects of combination with human recombinant interferon-beta.
Topics: Adenoviridae Infections; Adenoviruses, Simian; Animals; Antiviral Agents; Arabinofuranosyluracil; Chlorocebus aethiops; Dose-Response Relationship, Drug; Drug Synergism; Humans; Injections, Intravenous; Interferon Type I; Recombinant Proteins; Uridine; Viremia | 1990 |
Some electrochemical characteristics of synthetic analogs of nucleic acid components. II. Derivatives of uridine and arabinosyluracil. An attempt to find correlation between some of their properties.
Topics: Arabinofuranosyluracil; Electrochemistry; Polarography; Thioctic Acid; Uracil; Uridine | 1990 |
Inhibitory effects of 2'-fluorinated arabinosyl-pyrimidine nucleosides on woodchuck hepatitis virus replication in chronically infected woodchucks.
Topics: Administration, Oral; Animals; Antiviral Agents; Arabinofuranosyluracil; Chronic Disease; Cytarabine; Hepadnaviridae; Hepatitis, Viral, Animal; Uridine; Virus Replication | 1990 |
Mechanism of selective inhibition of varicella zoster virus replication by 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil.
Topics: Antiviral Agents; Arabinofuranosyluracil; Biological Transport; Cells, Cultured; DNA; DNA-Directed DNA Polymerase; DNA, Viral; Dose-Response Relationship, Drug; Herpesvirus 3, Human; Humans; In Vitro Techniques; Kinetics; Thymidine Kinase; Uridine; Virus Replication | 1989 |
[The modification of radiation effect by nucleoside related compounds on a murine tumor given with local radiotherapy and on survival following whole body irradiation].
Topics: Animals; Arabinofuranosyluracil; Combined Modality Therapy; Deoxyribonucleosides; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Neoplasms, Experimental; Radiation-Protective Agents; Radiation-Sensitizing Agents; Uridine | 1989 |
High-performance liquid chromatographic assay for cytosine arabinoside and uracil arabinoside in cerebrospinal fluid and plasma.
Topics: Arabinofuranosyluracil; Chromatography, High Pressure Liquid; Cytarabine; Humans; Leukemia; Spectrophotometry, Ultraviolet; Uridine | 1989 |
Modulation of the metabolism and pharmacokinetics of 1-beta-D-arabinofuranosylcytosine by 1-beta-D-arabinofuranosyluracil in leukemic mice.
Topics: Animals; Arabinofuranosyluracil; Cytarabine; Cytidine Deaminase; Kidney; Kinetics; Leukemia L5178; Leukemia, Experimental; Liver; Male; Mice; Mice, Inbred Strains; Uridine | 1989 |
Liquid-chromatographic monitoring of cytosine arabinoside and its metabolite, uracil arabinoside, in serum.
Topics: Aged; Arabinofuranosyluracil; Chromatography, High Pressure Liquid; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Spectrophotometry, Ultraviolet; Uridine | 1989 |
Synthesis and biological effects of 2'-fluoro-5-ethyl-1-beta-D-arabinofuranosyluracil.
Topics: Antiviral Agents; Arabinofuranosyluracil; Cell Line; Cell Survival; DNA; Simplexvirus; Structure-Activity Relationship; Thymidine Kinase; Uridine | 1987 |
Nucleosides. 146. 1-Methyl-5-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil, the C-nucleoside isostere of the potent antiviral agent 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)thymine (FMAU). Studies directed toward the synthesis of 2'-deoxy-2'-substit
Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Female; Humans; Mice; Mice, Inbred BALB C; Simplexvirus; Uridine | 1987 |
5-substituted 2'-fluoro-arabinonucleosides as potential antiviral agents.
Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Drug Evaluation, Preclinical; Humans; Simplexvirus; Structure-Activity Relationship; Uridine; Vero Cells; Vesicular stomatitis Indiana virus; Viral Plaque Assay | 1987 |
Synthesis and biological activities of 4-O-(difluoromethyl)-5-substituted-uracil nucleoside analogues.
Topics: Antiviral Agents; Arabinofuranosyluracil; Deoxyuridine; Humans; Simplexvirus; Structure-Activity Relationship; Uridine | 1988 |
Nucleosides. 150. Synthesis and some biological properties of 5-monofluoromethyl, 5-difluoromethyl, and 5-trifluoromethyl derivatives of 2'-deoxyuridine and 2'-deoxy-2'-fluoro-beta-D-arabinofuranosyluracil.
Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Cell Division; Chemical Phenomena; Chemistry; Deoxyuridine; Encephalitis; Herpes Simplex; Nucleosides; Radionuclide Imaging; Rats; Simplexvirus; Structure-Activity Relationship; Thymidylate Synthase; Uridine | 1988 |
Targeting of an inducible toxic phenotype in animal cells.
Topics: Acyclovir; Animals; Antiviral Agents; Arabinofuranosyluracil; Blotting, Northern; Blotting, Southern; Cell Line; Cell Line, Transformed; Cell Survival; Densitometry; DNA Replication; Gene Expression Regulation; Mice; Mice, Transgenic; Plasmids; Rats; Simplexvirus; Spleen; Thymidine Kinase; Thymus Gland; Transfection; Uridine | 1988 |
Effects of various nucleosides on antiviral activity and metabolism of 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil against herpes simplex virus types 1 and 2.
Topics: Antiviral Agents; Arabinofuranosyluracil; Chromatography, High Pressure Liquid; Nucleosides; Phosphorylation; Simplexvirus; Uridine | 1988 |
Comparison of two bromovinyl nucleoside analogs, 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil and E-5-(2-bromovinyl)-2'-deoxyuridine, with acyclovir in inhibition of Epstein-Barr virus replication.
Topics: Acyclovir; Arabinofuranosyluracil; Bromodeoxyuridine; DNA, Viral; Dose-Response Relationship, Drug; Drug Combinations; Herpesvirus 4, Human; Peptide Biosynthesis; Uridine; Virus Replication | 1988 |
Efficacy of 5-vinyl-1-beta-D-arabinofuranosyluracil (VaraU) against herpes simplex virus type 2 strains in cell cultures and against experimental herpes encephalitis in mice: comparison with acyclovir and foscarnet.
Topics: Acyclovir; Animals; Antiviral Agents; Arabinofuranosyluracil; Cells, Cultured; Encephalitis; Female; Foscarnet; Herpes Simplex; Mice; Organophosphorus Compounds; Phosphonoacetic Acid; Simplexvirus; Uridine; Virus Replication | 1987 |
Enhanced serum concentrations of Ara-C using suppositories containing tetrahydrouridine as a deamination inhibitor of Ara-C.
Topics: Animals; Arabinofuranosyluracil; Biological Availability; Cytarabine; Deamination; Dogs; Kinetics; Salicylates; Salicylic Acid; Suppositories; Tetrahydrouridine; Uridine | 1986 |
Effect of (E)-5-(2-bromovinyl)- and 5-vinyl-1-beta-D-arabinofuranosyluracil on Epstein-Barr virus antigen expression in P3HR-1 cells: comparison with acyclovir.
Topics: Acyclovir; Antigens, Viral; Antiviral Agents; Arabinofuranosyluracil; Capsid Proteins; Cell Line; Herpesvirus 4, Human; Humans; Uridine | 1987 |
Efficacy of (E)-5-(2-bromovinyl)- and 5-vinyl-1-beta-D-arabinofuranosyluracil against acute herpes simplex virus keratitis and the establishment of latency: comparison with acyclovir and bromovinyldeoxyuridine.
Topics: Acute Disease; Acyclovir; Animals; Antiviral Agents; Arabinofuranosyluracil; Bromodeoxyuridine; Chemical Phenomena; Chemistry; Keratitis, Dendritic; Rabbits; Simplexvirus; Uridine | 1987 |
Effect of 2'-fluoro-5-methyl-ara-uracil and cyclophosphamide on herpes simplex virus infection in guinea pigs.
Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Cyclophosphamide; Dose-Response Relationship, Drug; Female; Guinea Pigs; Herpes Genitalis; Uridine | 1987 |
Phase I trial of 1-(2'-deoxy-2'-fluoro-1-beta-D-arabinofuranosyl)-5-methyluracil (FMAU).
Topics: Adult; Aged; Antineoplastic Agents; Arabinofuranosyluracil; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Central Nervous System Diseases; Drug Evaluation; Female; Humans; Leukocyte Count; Lung Neoplasms; Male; Middle Aged; Nausea; Neoplasms; Platelet Count; Uridine; Vomiting | 1985 |
Mechanism of selective inhibition of human cytomegalovirus replication by 1-beta-D-arabinofuranosyl-5-fluorouracil.
Topics: Antiviral Agents; Arabinofuranosyluracil; Arabinonucleosides; Arabinonucleotides; Cytomegalovirus; DNA-Directed DNA Polymerase; Fluorouracil; Kinetics; Nucleic Acid Synthesis Inhibitors; Structure-Activity Relationship; Thymine Nucleotides; Uridine; Virus Replication | 1985 |
Treatment of experimental herpes simplex virus type 1 encephalitis in mice with (E)-5-(2-bromovinyl)- and 5-vinyl-1-beta-D-arabinofuranosyluracil: comparison with bromovinyl-deoxyuridine and acyclovir.
Topics: Acyclovir; Animals; Arabinofuranosyluracil; Bromodeoxyuridine; Cells, Cultured; Encephalitis; Female; Foscarnet; Herpes Simplex; Humans; Mice; Phosphonoacetic Acid; Simplexvirus; Uridine; Viral Plaque Assay | 1986 |
Nucleosides. 139. Synthesis and anticytomegalovirus and antiherpes simplex virus activity of 5'-modified analogues of 2'-fluoroarabinosylpyrimidine nucleosides.
Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Cytarabine; Cytomegalovirus; Drug Evaluation, Preclinical; Fluorine; Indicators and Reagents; Magnetic Resonance Spectroscopy; Simplexvirus; Structure-Activity Relationship; Uridine; Vero Cells | 1987 |
A proposed mechanism for the selective inhibition of human cytomegalovirus replication by 1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-5-fluorouracil.
Topics: Antiviral Agents; Arabinofuranosyluracil; Arabinonucleosides; Arabinonucleotides; Cell Line; Cell Survival; Cytomegalovirus; Fluorouracil; Nucleic Acid Synthesis Inhibitors; Phosphorylation; Protein-Tyrosine Kinases; Uridine; Viral Plaque Assay; Virus Replication | 1987 |
1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-ethyluracil. A highly selective antiherpes simplex agent.
Topics: Acyclovir; Animals; Arabinofuranosyluracil; Cell Line; Chemical Phenomena; Chemistry; Encephalitis; Female; Guinea Pigs; Herpes Simplex; Mice; Simplexvirus; Skin Diseases; Thymidine Kinase; Uridine | 1987 |
Antiviral activity of various 1-beta-D-arabinofuranosyl-E-5-halogenovinyluracils and E-5-bromovinyl-2'-deoxyuridine against salmon herpes virus, Oncorhynchus masou virus (OMV).
Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Bromodeoxyuridine; Cell Line; Chromatography, High Pressure Liquid; DNA Polymerase II; Fish Diseases; Herpesviridae; Herpesviridae Infections; Nucleic Acid Synthesis Inhibitors; Salmon; Uridine | 1987 |
Effect of acyclovir on the uptake of 131I-labelled 1-(2'fluoro-2'-deoxy-beta-D-arabinofuranosyl)-5-iodouracil in herpes infected cells.
Topics: Acyclovir; Animals; Arabinofuranosyluracil; Cells, Cultured; Simplexvirus; Time Factors; Uridine | 1987 |
Structure and conformation of a nucleoside analog 5-nitro-1-beta-D-arabinofuranosyluracil.
Topics: Arabinofuranosyluracil; Computer Simulation; Models, Molecular; Molecular Conformation; Molecular Structure; Uridine | 1988 |
Nucleosides. CXLIII. Synthesis of 5'-deoxy-5'-substituted-2,2'-anhydro-1-(beta-D-arabinofuranosyl) uracils. A new 2,5'- to 2,2'-anhydro-nucleoside transformation. Studies directed toward the synthesis of 2'-deoxy-2'-substituted arabino nucleosides. (4).
Topics: Acetylation; Arabinofuranosyluracil; Arabinonucleosides; Chemical Phenomena; Chemistry; Uridine | 1987 |
Does the metabolite uracil arabinoside inhibit cytosine arabinoside (Ara-C) penetration into the cerebrospinal fluid during high-dose Ara-C therapy?
Topics: Adult; Arabinofuranosyluracil; Biological Transport; Blood-Brain Barrier; Cytarabine; Half-Life; Humans; Kinetics; Leukemia, Myeloid, Acute; Male; Uridine | 1986 |
Comparative metabolism of E-5-(2-bromovinyl)-2'-deoxyuridine and 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil in herpes simplex virus-infected cells.
Topics: Arabinofuranosyluracil; Bromodeoxyuridine; Cell Line; Chromatography, High Pressure Liquid; Fibroblasts; Herpes Simplex; Humans; Osteosarcoma; Uridine | 1987 |
Selective inhibitory effects of (S)-9-(3-hydroxy-2-phosphonyl-methoxypropyl) adenine and 1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-5-iodouracil on seal herpesvirus (phocid herpesvirus 1) infection in vitro.
Topics: Adenine; Animals; Antiviral Agents; Arabinofuranosyluracil; Cells, Cultured; Herpesviridae; Organophosphonates; Organophosphorus Compounds; Seals, Earless; Uridine | 1987 |
Pharmacology of combination chemotherapy of cytosine arabinoside (ara-C) and uracil arabinoside (ara-U) or tetrahydrouridine (THU) against murine leukemia L1210/0 in tumor-bearing mice.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosyluracil; Cytarabine; Deamination; Leukemia L1210; Male; Mice; Tetrahydrouridine; Time Factors; Uridine | 1987 |
Activity of 1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-5-iodouracil against simian varicella virus infections in African green monkeys.
Topics: Administration, Oral; Animals; Antiviral Agents; Arabinofuranosyluracil; Aspartate Aminotransferases; Chickenpox; Chlorocebus aethiops; Female; Injections, Intravenous; Male; Time Factors; Uridine | 1986 |
In vivo studies on high-dose 1-beta-D-arabinofuranosylcytosine (HDara-C) and 1-beta-D-arabinofuranosyluracil (ara-U) with respect to pharmacokinetics, cell kinetics, and cytotoxicity in a rat myelocytic leukemia model (BNML).
Topics: Animals; Arabinofuranosyluracil; Cell Cycle; Colony-Forming Units Assay; Cytarabine; Cytidine Deaminase; Disease Models, Animal; Half-Life; Humans; Kinetics; Leukemia, Myeloid, Acute; Nucleoside Deaminases; Rats; Uridine | 1985 |
Ab initio studies of the antiviral drug 1-(2-fluoro-2-deoxy-beta-D-arabinofuranosyl) thymine.
Topics: Antiviral Agents; Arabinofuranosyluracil; Herpesviridae; Molecular Conformation; Structure-Activity Relationship; Uridine | 1985 |
Effect of uracil arabinoside on metabolism and cytotoxicity of cytosine arabinoside in L5178Y murine leukemia.
Topics: Animals; Arabinofuranosyluracil; Cytarabine; Cytotoxicity, Immunologic; Drug Interactions; Humans; Kinetics; Leukemia L5178; Leukemia, Experimental; Tumor Stem Cell Assay; Uridine | 1985 |
In vitro and in vivo antiviral activity of 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil (BV-araU) and related compounds.
Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Encephalitis; Herpes Simplex; Male; Mice; Simplexvirus; Uridine | 1984 |
Investigation of antiviral activity of 1-beta-D-arabinofuranosylthymine (ara-T) and 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil (BV-ara-U) in monkeys infected with simian varicella virus.
Topics: Animals; Arabinofuranosyluracil; Arabinonucleosides; Chickenpox; Chlorocebus aethiops; Herpesviridae Infections; Nervous System; Neurons; Thymidine; Uridine | 1984 |
Acute cerebellar toxicity after high-dose cytarabine associated with CNS accumulation of its metabolite, uracil arabinoside.
Topics: Arabinofuranosyluracil; Carcinoma, Small Cell; Cerebellar Diseases; Cytarabine; Humans; Lung Neoplasms; Male; Middle Aged; Uridine | 1984 |
Inhibitory effects of various 5-halogenated derivatives of 1-beta-D-arabinofuranosyluracil 5'-triphosphate on DNA polymerases from murine cells and oncornavirus: substituent effects on inhibitory action.
Topics: Animals; Arabinofuranosyluracil; Arabinonucleotides; Kinetics; Mice; Nucleic Acid Synthesis Inhibitors; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Uridine; Uridine Triphosphate | 1982 |
Treatment of primary acute genital herpes in guinea pigs by intraperitoneal administration of fluoropyrimidines.
Topics: Acyclovir; Animals; Antiviral Agents; Arabinofuranosyluracil; Cytarabine; Female; Foscarnet; Guinea Pigs; Herpes Genitalis; Injections, Intraperitoneal; Male; Phosphonoacetic Acid; Uridine; Virus Replication | 1984 |
Antiherpesviral activity and inhibitory action on cell growth of 5-alkenyl derivatives of 1-beta D-arabinofuranosyluracil.
Topics: Antiviral Agents; Arabinofuranosyluracil; Fibroblasts; Humans; Simplexvirus; Uridine | 1980 |
Antiherpesviral and anticellular effects of 1-beta-D-arabinofuranosyl-E-5-(2-halogenovinyl) uracils.
Topics: Antiviral Agents; Arabinofuranosyluracil; Cell Division; Cell Line; Cells, Cultured; Cytopathogenic Effect, Viral; DNA, Viral; Simplexvirus; Uridine; Virus Replication | 1981 |
Antiherpes activity of [E]-5-(1-propenyl)-2'-deoxyuridine and 5-(1-propenyl)-1-beta-D-arabinofuranosyluracil.
Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Arabinonucleosides; Cell Division; Cell Line; Chlorocebus aethiops; Deoxyuridine; DNA; DNA, Viral; Guinea Pigs; Herpes Simplex; Phosphorylation; Simplexvirus; Thymidine; Uridine; Viral Plaque Assay | 1981 |
Distribution, metabolism, and excretion of 1-(2-fluoro-2-deoxy-beta-D- arabinofuranosyl)thymine and 1-(2-fluoro-2-deoxy-beta-D-arabinofuranosyl)-5- iodocytosine.
Topics: Absorption; Animals; Arabinofuranosyluracil; Chromatography, High Pressure Liquid; Cytarabine; Digestive System; Dogs; Female; Kidney; Male; Metabolic Clearance Rate; Mice; Rats; Simplexvirus; Species Specificity; Tissue Distribution; Uridine; Virus Replication | 1983 |
Epstein-Barr virus: inhibition of replication by three new drugs.
Topics: Acyclovir; Antiviral Agents; Arabinofuranosyluracil; Bromodeoxyuridine; Cytarabine; DNA Replication; Herpesvirus 4, Human; Uridine; Virus Replication | 1983 |
Activity of 1-(2'-fluoro-2'-deoxy-beta-D-arabinofuranosyl)thymine against herpes simplex virus in cell cultures and rabbit eyes.
Topics: Acyclovir; Animals; Antiviral Agents; Arabinofuranosyluracil; Cells, Cultured; Drug Resistance, Microbial; Idoxuridine; Keratitis, Dendritic; Male; Rabbits; Simplexvirus; Uridine; Vidarabine | 1983 |
Antiherpes activity of (E)-5-(2-bromovinyl)- and 5-vinyl-1-beta-D-arabinofuranosyluracil and some other 5-substituted uracil arabinosyl nucleosides in two different cell lines.
Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Cell Line; Fibroblasts; Humans; Kidney; Simplexvirus; Structure-Activity Relationship; Uridine | 1983 |
Nucleosides. 129. Synthesis of antiviral nucleosides: 5-alkenyl-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)uracils.
Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Cell Line; Chlorocebus aethiops; Drug Evaluation, Preclinical; Humans; Indicators and Reagents; Kidney; Lymphocyte Activation; Lymphocytes; Magnetic Resonance Spectroscopy; Simplexvirus; Structure-Activity Relationship; Uridine | 1984 |
Strains of varicella-zoster virus resistant to 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil.
Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Chlorocebus aethiops; Cloning, Molecular; DNA, Viral; Drug Resistance, Microbial; Embryo, Mammalian; Fibroblasts; Guinea Pigs; Herpesvirus 3, Human; Kidney; Thymidine; Thymidine Kinase; Uridine; Viral Plaque Assay; Virus Cultivation | 1984 |
Sensitive radioimmunoassay for cytarabine and uracil arabinoside in plasma.
Topics: Animals; Antibody Specificity; Arabinofuranosyluracil; Cross Reactions; Cytarabine; Haptens; Metabolic Clearance Rate; Mice; Radioimmunoassay; Uridine | 1984 |
5-substituted arabinofuranosyluracil nucleosides: synthesis and antiviral properties.
Topics: Antiviral Agents; Arabinofuranosyluracil; Chemical Phenomena; Chemistry; Circular Dichroism; Magnetic Resonance Spectroscopy; Spectrophotometry, Ultraviolet; Stereoisomerism; Structure-Activity Relationship; Uridine | 1984 |
The synthesis of [36Cl]-, [82Br]- and [123I]-labelled 1-(3'-chloro-(bromo and iodo)-3'-deoxy-beta-D-arabinofuranosyl)uracil.
Topics: Arabinofuranosyluracil; Bromine; Chlorine; Humans; Iodine Radioisotopes; Isotope Labeling; Neoplasms; Radioisotopes; Radionuclide Imaging; Uridine | 1984 |
Tumor uptake of radiolabelled pyrimidine bases and pyrimidine nucleosides in animal models: VI. 1-(3'-[36Cl]-chloro-, 1-(3'-[82Br]-bromo- and 1-(3'-[123I]-Iodo-3'-deoxy-beta-D-arabinofuranosyl)uracil.
Topics: Animals; Arabinofuranosyluracil; Bromine; Chlorine; Female; Iodine Radioisotopes; Male; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Radioisotopes; Radionuclide Imaging; Rats; Rats, Inbred Strains; Tissue Distribution; Uridine | 1984 |
High-performance liquid chromatographic assay for cytosine arabinoside, uracil arabinoside and some related nucleosides.
Topics: Arabinofuranosyluracil; Child; Chromatography, High Pressure Liquid; Cytarabine; Cytidine; Deoxycytidine; Humans; Infusions, Parenteral; Kinetics; Leukemia, Myeloid, Acute; Uridine | 1983 |
Therapeutic activities of 1-(2-fluoro-2-deoxy-beta-D-arabinofuranosyl)-5-iodocytosine and -thymine alone and in combination with acyclovir and vidarabine in mice infected intracerebrally with herpes simplex virus.
Topics: Acyclovir; Administration, Oral; Animals; Antiviral Agents; Arabinofuranosyluracil; Brain; Cytarabine; Drug Therapy, Combination; Encephalitis; Female; Herpes Simplex; Injections, Intraperitoneal; Mice; Uridine; Vidarabine | 1983 |
Simultaneous analysis of 1-beta-D-arabinofuranosylcytosine, 1-beta-D-arabinofuranosyluracil and sodium salicylate in biological samples by high-performance liquid chromatography.
Topics: Animals; Arabinofuranosyluracil; Chromatography, High Pressure Liquid; Cytarabine; Dogs; Sodium Salicylate; Suppositories; Time Factors; Uridine | 1983 |
Alteration of the pharmacokinetics of high-dose ara-C by its metabolite, high ara-U in patients with acute leukemia.
Topics: Acute Disease; Arabinofuranosyluracil; Chromatography, High Pressure Liquid; Cytarabine; Cytidine Deaminase; Dose-Response Relationship, Drug; Humans; Infusions, Parenteral; Kinetics; Leukemia; Models, Biological; Nucleoside Deaminases; Radioimmunoassay; Time Factors; Uridine | 1983 |
Comparison of 2'-fluoro-arabinosyl pyrimidine nucleosides and 1-beta-D-arabinofuranosylcytosine on immunological parameters in vitro.
Topics: Animals; Antibody Formation; Antibody-Producing Cells; Arabinofuranosyluracil; Cell Survival; Cytarabine; Immune Tolerance; Mice; Spleen; Uridine | 1983 |
Diagnostic imaging of herpes simplex virus encephalitis using a radiolabeled antiviral drug: autoradiographic assessment in an animal model.
Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Autoradiography; Blood-Brain Barrier; Brain; Carbon Radioisotopes; Cerebral Ventricles; Choroid Plexus; Encephalitis; Ependyma; Female; Herpes Simplex; Kinetics; Radionuclide Imaging; Rats; Uridine | 1984 |
Mechanism of action of 2',5-difluoro-1-arabinosyluracil.
Topics: Animals; Arabinofuranosyluracil; Arabinonucleotides; Cell Line; Cell Survival; Chromatography, Gel; Deoxyuracil Nucleotides; Fluorodeoxyuridylate; Lymphoma; Mice; Spectrophotometry, Ultraviolet; Thymidylate Synthase; Uridine | 1983 |
Potent antiviral 2'-fluoro-arabinosyl pyrimidine nucleosides: lack of mutagenic activity.
Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Cell Line; Cricetinae; Cricetulus; Cytarabine; DNA; Liver; Mutagenicity Tests; Rats; Rats, Inbred Strains; Salmonella typhimurium; Uridine | 1982 |
[The simultaneous determination of Ara-U and Ara-C, urinary metabolites of N4-behenoyl-1-beta-D-arabinofuranosylcytosine by mass fragmentography (author's transl)].
Topics: Antineoplastic Agents; Arabinofuranosyluracil; Cytarabine; Gas Chromatography-Mass Spectrometry; Humans; Uridine | 1982 |
Biochemical effects of 2'-fluoro-5-methyl-1-beta-D-arabinofuranosyluracil and 2'-fluoro-5-iodo-1-beta-D-arabinofuranosylcytosine in mouse leukemic cells sensitive and resistant to 1-beta-D-arabinofuranosylcytosine.
Topics: Animals; Arabinofuranosyluracil; Cell Survival; Cytarabine; Deoxycytidine; DNA Replication; Kinetics; Leukemia L1210; Leukemia, Experimental; Mice; Thymidine; Uridine | 1982 |
Quantitative autoradiographic mapping of herpes simplex virus encephalitis with a radiolabeled antiviral drug.
Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Autoradiography; Cytarabine; Encephalitis; Herpes Simplex; Rats; Uridine | 1982 |
Determination of 1-beta-D-arabinofuranosylcytosine and 1-beta-D-arabinofuranosyluracil in human plasma by high-performance liquid chromatography.
Topics: Arabinofuranosyluracil; Chromatography, High Pressure Liquid; Cytarabine; Humans; Leukemia; Uridine | 1981 |
Determination of cytarabine and uracil arabinoside in human plasma and cerebrospinal fluid by high-performance liquid chromatography.
Topics: Arabinofuranosyluracil; Chromatography, High Pressure Liquid; Cytarabine; Humans; Leukemia; Time Factors; Uridine | 1981 |
Structure-activity relationship of the affinity of 5-substituted uracil nucleoside analogues for varicella-zoster virus thymidine kinase and their activity against varicella-zoster virus.
Topics: Antineoplastic Agents; Antiviral Agents; Arabinofuranosyluracil; Arabinonucleosides; Deoxyuracil Nucleotides; Growth Inhibitors; Herpesvirus 3, Human; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Structure-Activity Relationship; Thymidine Kinase; Tumor Cells, Cultured; Uridine | 1997 |
Rationale of 5-(125)I-iodo-4'-thio-2'-deoxyuridine as a potential iodinated proliferation marker.
Topics: Animals; Arabinofuranosyluracil; Cell Division; Deoxyuridine; Humans; Iodine Radioisotopes; Isotope Labeling; Mice; Mice, Inbred C57BL; Monosaccharides; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; Uracil; Uridine | 2002 |
In vivo evaluation of the uptake of [(123)I]FIAU, [(123)I]IVFRU and [(123)I]IVFAU by normal mouse brain: potential for noninvasive assessment of HSV-1 thymidine kinase gene expression in gliomas.
Topics: Animals; Arabinofuranosyluracil; Blood-Brain Barrier; Brain; Brain Neoplasms; Floxuridine; Gene Expression; Glioma; Herpesvirus 1, Human; Iodine Radioisotopes; Male; Mice; Mice, Nude; Thymidine Kinase; Tissue Distribution; Uridine | 2008 |
N⁴-[Alkyl-(hydroxyphosphono)phosphonate]-cytidine-new drugs covalently linking antimetabolites (5-FdU, araU or AZT) with bone-targeting bisphosphonates (alendronate or pamidronate).
Topics: Alendronate; Animals; Antimetabolites, Antineoplastic; Arabinofuranosyluracil; Bone and Bones; Bone Density Conservation Agents; Cell Line, Tumor; Cytidine; Diphosphonates; Drug Screening Assays, Antitumor; Durapatite; Fluorouracil; Humans; Macrophages; Mice; Pamidronate; Uridine; Zidovudine | 2011 |
2,2'-Anhydro-1-(3',5'-di-O-acetyl-β-D-arabinofuranosyl)uracil, a cyclouridine nucleoside with a C4'-endo furanosyl conformation.
Topics: Arabinofuranosyluracil; Crystallography, X-Ray; Hydrogen Bonding; Molecular Conformation; Nucleosides; Uridine | 2013 |