arabinofuranosyluracil and sorivudine

arabinofuranosyluracil has been researched along with sorivudine in 88 studies

Research

Studies (88)

TimeframeStudies, this research(%)All Research%
pre-199014 (15.91)18.7374
1990's64 (72.73)18.2507
2000's8 (9.09)29.6817
2010's2 (2.27)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Herrmann, G; Lin, JC; Pagano, JS; Reefschläger, J1
Bonner, DP; Field, AK; Huang, JL; Mitroka, JG; Olsen, S; Soike, K; Stouffer, B; Swerdel, M; Tu, JI; Tuomari, AV1
Ashida, N; Baba, M; Ikeda, T; Machida, H; Sakata, S; Shigeta, S1
Bowler, WA; Brodine, SK; Burgos, C; Chamberlin, CJ; LaRocco, A; Oldfield, EC; Sawyer, MH; Wallace, MR; Wu, YN1
Hayashi, K; Namazue, J; Ochiai, H; Ogino, S; Okuno, T; Shiraki, K; Takahashi, M; Yamanishi, K1
Machida, H; Suzutani, T1
Jagoda, E; Mantha, S; Ogan, M; Stouffer, B; Tsay, HM; Tu, JI; Turabi, N; Yost, F1
Ijichi, K; Machida, H; Takezawa, J1
Hamada, T; Hiraoka, A; Horiuchi, A; Kanamaru, A; Masaoka, T; Nagai, K; Niimura, M; Takahashi, M1
Machida, H; Watanabe, Y1
Daikoku, T; Nishiyama, Y; Yamada, Y; Yamamoto, N1
Hayashi, K; Machida, H; Nishitani, M; Suzutani, T1
Cohen, AI; Whigan, DB1
Honess, RW; Lacey, SF; Powell, KL; Purifoy, DJ; Suzutani, T1
Machida, H1
Ashida, N; Ijichi, K; Machida, H1
Honda, M; Ijichi, K; Machida, H; Niimura, M; Ohta, A1
Machida, H; Takezawa, J1
Machida, H; Nishitani, M1
Ashida, N; Ikeda, T; Machida, H1
Niimura, M1
Konno, K; Kumagai, M; Machida, H; Mori, S; Shigeta, S; Watanabe, Y; Yokota, T1
Azuma, M; Machida, H; Sakuma, T; Suzutani, T1
Machida, H; Sakuma, T; Suzutani, T1
Lin, JC; Machida, H1
Färber, I; Herrmann, G; Klinger, C; Reefschläger, J; Thiel, KD; Wutzler, P1
Rajcáni, J; Reefschläger, J1
Herrmann, G; Reefschläger, J; Thiel, KD; Wutzler, P1
Machida, H; Saneyoshi, M; Suzuki, S1
Gräf, M; Herrmann, G; Reefschläger, J; Töpke, H; Wutzler, P1
Ayisi, NK; De Clercq, E; Machida, H; Sacks, SL; Wall, RA; Wanklin, RJ1
Machida, H; Sakata, S1
Baskin, G; Cantrell, C; Gerone, P; Soike, KF1
Kuninaka, A; Machida, H; Sakata, S; Yoshino, H1
Sakuma, T1
Asai, T; Cho, R; Nakamura, H; Oh, H; Sato, H1
Burdge, DR; Gage, L; Lindley, JI; Sacks, SL; Voigt, R1
Kondo, S1
Bevilacqua, F; Collins, P; Darby, G; Davis-Poynter, N; Gower, D; Worrallo, J1
Foxworthy, D; Kemp, B; Pinnolis, MK1
Ashida, N; Kano, F; Machida, H; Nishitani, M; Sakata, S; Watanabe, Y1
Schuster, AE; Whigan, DB1
Easterbrook, P; Wood, MJ1
Ijichi, K; Komatsu, M; Machida, H; Mochizuki, K; Tanahashi, T; Torisaki, M; Yamashita, Y1
Kitada, K; Mochida, A; Nakamura, H; Omori, S1
Swinbanks, D1
Ashida, N; Machida, H; Nishitani, M1
Gnann, JW1
Honess, RW; Machida, H; Suzutani, T1
Ashida, N; Ijichi, K; Machida, H; Watanabe, Y1
Kawai, H; Suzutani, T; Yoshida, I1
Biron, KK; Phelps, WC; Talarico, CL1
Ashida, N; Ijichi, K; Machida, H; Varia, S1
Whitley, RJ2
Arvin, AM; Bowler, WA; Chamberlin, CJ; Colopy, MW; Harkins, J; LaRocco, A; Oldfield, EC; Sawyer, MH; Wallace, MR1
Hirsch, HH; Hirschel, B; Miner, R; von Gunten, S; Wintsch, J; Wunderli, W1
Azuma, M; Koyano, S; Suzutani, T; Yoshida, I1
Akiyama, H; Imaoka, T; Kawaguchi, T; Miyauchi, S; Motoyama, M; Odomi, M; Okada, T1
Ikeda, K; Kawaguchi, K; Nagayama, S; Nakamura, Y; Nishiyama, T; Ogura, K; Ogura, Y; Okuda, H; Watabe, T; Yamaguchi, S1
Watabe, T1
Cassady, KA; Whitley, RJ1
Akimoto, S; Kataoka, K; Kinouchi, T; Matsuda, Y; Nakayama, H; Ohnishi, Y1
Ikeda, K; Kawaguchi, Y; Nagayama, S; Nakamura, Y; Nishiyama, T; Ogura, K; Okuda, H; Watabe, T; Yamaguchi, S1
Diasio, RB; Haworth, S; Lee, PC; McCrary, MM; Olsen, SJ; Raymond, R; Tyring, SK; Yan, J1
Boag, F; Bodsworth, NJ; Borleffs, JC; Burdge, D; Colebunders, R; DeHertogh, D; Evans, BA; Généreux, M; Modai, J; Pacelli, L; Thomas, M; Thomis, J1
Jurima-Romet, M; Li, AP1
Ogura, K; Okuda, H; Watabe, T1
Arakawa, K; Fukushima, M; Kato, A; Kawaguchi, Y; Nagayama, S; Nishiyama, T; Ogura, K; Okuda, H; Takubo, H; Watabe, T1
Ashida, N; Machida, H; Sakata, S1
Baum, KF; Borucki, MJ; Cloud, GA; Crumpacker, CS; DeHertogh, DA; Gnann, JW; Joseph, WP; Lalezari, JP; Mertz, GJ; Sherrill, LC; Smith, JA; Soong, SJ; Steigbigel, RT; Tyring, SK; Whitley, RJ1
Wutzler, P1
Diasio, RB1
Chern, KC; Conrad, D; Holland, GN; Holsclaw, DS; Margolis, TP; Schwartz, LK1
Kato, A; Ogura, K; Okuda, H; Takubo, H; Watabe, T1
Bartz-Schmidt, KU; Heimann, K; Kirchhof, B; Rosenthal, G; Walter, P1
Balzarini, J; Baudson, N; Calberg-Bacq, CM; Cool, V; De Leval, L; Debrus, S; Degrève, B; Grignet-Debrus, C; Velu, T1
Fujimura, A; Harada, K1
Desai, D; Jain, N; Janjikhel, R; Lang, B; Li, D1
Balzarinia, J; De Clercq, E; Degrève, B; Durini, E; Karlsson, A; Manfredini, S; Porcu, L; Zhu, C1
Bowers, M1
De Clercq, E; Naesens, L1
Nishiyama, T; Ogura, K; Watabe, T1
Andrei, G; De Clercq, E; Snoeck, R1
Konagaya, A; Satou, K; Yoshikawa, S1
Li-Wan-Po, A1
Andrei, G; Coen, N; Duraffour, S; Snoeck, R; Topalis, D1

Reviews

11 review(s) available for arabinofuranosyluracil and sorivudine

ArticleYear
Apoptosis by antitumor agents and other factors in relation to cell cycle checkpoints.
    Journal of radiation research, 1995, Volume: 36, Issue:1

    Topics: Antineoplastic Agents; Antiviral Agents; Apoptosis; Arabinofuranosyluracil; Cell Cycle; G1 Phase; G2 Phase; Humans

1995
Successors to acyclovir.
    The Journal of antimicrobial chemotherapy, 1994, Volume: 34, Issue:3

    Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Arabinofuranosyluracil; Chickenpox; Drug Resistance, Microbial; Famciclovir; Herpes Simplex; Herpes Zoster; Humans; Valacyclovir; Valine

1994
New antivirals with activity against varicella-zoster virus.
    Annals of neurology, 1994, Volume: 35 Suppl

    Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Arabinofuranosyluracil; Drugs, Investigational; Famciclovir; Herpes Zoster; Humans; Prodrugs; Valacyclovir; Valine

1994
Sorivudine: a promising drug for the treatment of varicella-zoster virus infection.
    Neurology, 1995, Volume: 45, Issue:12 Suppl 8

    Topics: Antiviral Agents; Arabinofuranosyluracil; Herpes Zoster; Humans

1995
Sorivudine: a potent inhibitor of varicella zoster virus replication.
    Advances in experimental medicine and biology, 1996, Volume: 394

    Topics: Adult; Animals; Antiviral Agents; Arabinofuranosyluracil; Herpesvirus 3, Human; Humans; Virus Replication

1996
New therapeutic approaches to the alphaherpesvirus infections.
    The Journal of antimicrobial chemotherapy, 1997, Volume: 39, Issue:2

    Topics: 2-Aminopurine; Acyclovir; Alphaherpesvirinae; Antibodies, Monoclonal; Arabinofuranosyluracil; Cidofovir; Cytosine; Famciclovir; Guanine; Herpesviridae Infections; Humans; Organophosphonates; Organophosphorus Compounds; Valacyclovir; Valine

1997
Overview: pharmacokinetic drug-drug interactions.
    Advances in pharmacology (San Diego, Calif.), 1997, Volume: 43

    Topics: Arabinofuranosyluracil; Contraceptives, Oral; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Female; Heart Diseases; Humans; Isoenzymes; Liver; Pharmacokinetics; Pregnancy; Pregnancy, Unwanted; Terfenadine

1997
[Lethal drug interactions of the new antiviral, sorivudine, with anticancer prodrugs of 5-fluorouracil].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1997, Volume: 117, Issue:10-11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antiviral Agents; Arabinofuranosyluracil; Dihydrouracil Dehydrogenase (NADP); Drug Interactions; Fluorouracil; Humans; NADP; Oxidoreductases; Prodrugs; Rats

1997
Antiviral therapy of herpes simplex and varicella-zoster virus infections.
    Intervirology, 1997, Volume: 40, Issue:5-6

    Topics: 2-Aminopurine; Acyclovir; Administration, Oral; Antiviral Agents; Arabinofuranosyluracil; Bromodeoxyuridine; Chickenpox; Drug Resistance, Microbial; Encephalitis, Viral; Famciclovir; Herpes Genitalis; Herpes Labialis; Herpes Simplex; Herpes Zoster; Humans; Immunocompromised Host; Prodrugs; Simplexvirus; Valacyclovir; Valine

1997
Recent developments in herpesvirus therapy.
    Herpes : the journal of the IHMF, 2001, Volume: 8, Issue:1

    Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Arabinofuranosyluracil; Bromodeoxyuridine; Cidofovir; Clinical Trials as Topic; Cytosine; Famciclovir; Foscarnet; Ganciclovir; Guanine; Herpesviridae Infections; Humans; Organophosphonates; Organophosphorus Compounds; Thionucleotides; Valacyclovir; Valine

2001
[Molecular toxicological mechanism of the lethal interactions of the new antiviral drug, sorivudine, with 5-fluorouracil prodrugs and genetic deficiency of dihydropyrimidine dehydrogenase].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2002, Volume: 122, Issue:8

    Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Bromouracil; Dihydrouracil Dehydrogenase (NADP); Drug Interactions; Drug Therapy, Combination; Fluorouracil; Humans; NADP; Oxidoreductases; Prodrugs; Rats

2002

Trials

8 trial(s) available for arabinofuranosyluracil and sorivudine

ArticleYear
Detection of varicella-zoster virus DNA in the oropharynx and blood of patients with varicella.
    The Journal of infectious diseases, 1992, Volume: 166, Issue:4

    Topics: Adult; Antiviral Agents; Arabinofuranosyluracil; Base Sequence; Cells, Cultured; Chickenpox; DNA, Viral; Herpesvirus 3, Human; Humans; Male; Molecular Sequence Data; Oropharynx; Polymerase Chain Reaction

1992
Clinical effect of BV-araU on varicella-zoster virus infection in immunocompromised patients with haematological malignancies.
    The Journal of antimicrobial chemotherapy, 1991, Volume: 27, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antiviral Agents; Arabinofuranosyluracil; Chickenpox; Child; Hematologic Diseases; Herpesvirus 3, Human; Humans; Immune Tolerance; Middle Aged; Remission Induction

1991
A double-blind clinical study in patients with herpes zoster to establish YN-72 (Brovavir) dose.
    Advances in experimental medicine and biology, 1990, Volume: 278

    Topics: Adult; Analgesia; Antiviral Agents; Arabinofuranosyluracil; Dose-Response Relationship, Drug; Double-Blind Method; Herpes Zoster; Humans; Placebos

1990
Manual and automated determination of 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil and its metabolite (E)-5-(2-bromovinyl)uracil in urine.
    Journal of chromatography. B, Biomedical applications, 1995, Feb-17, Volume: 664, Issue:2

    Topics: Antiviral Agents; Arabinofuranosyluracil; Autoanalysis; Bromouracil; Chromatography, High Pressure Liquid; Humans; Robotics

1995
Treatment of adult varicella with sorivudine: a randomized, placebo-controlled trial.
    The Journal of infectious diseases, 1996, Volume: 174, Issue:2

    Topics: Administration, Oral; Adult; Antiviral Agents; Arabinofuranosyluracil; Chickenpox; Cohort Studies; Dose-Response Relationship, Drug; Double-Blind Method; Female; Herpesvirus 3, Human; Hospitals, Military; Humans; Immunocompetence; Male; Placebos; Polymerase Chain Reaction; Skin

1996
The effect of sorivudine on dihydropyrimidine dehydrogenase activity in patients with acute herpes zoster.
    Clinical pharmacology and therapeutics, 1997, Volume: 61, Issue:5

    Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Analysis of Variance; Antiviral Agents; Arabinofuranosyluracil; Bromouracil; Chromatography, High Pressure Liquid; Dihydrouracil Dehydrogenase (NADP); Female; Herpes Zoster; Humans; Leukocytes, Mononuclear; Male; Middle Aged; Oxidoreductases; Software; Uracil

1997
Evaluation of sorivudine (BV-araU) versus acyclovir in the treatment of acute localized herpes zoster in human immunodeficiency virus-infected adults. The Multinational Sorivudine Study Group.
    The Journal of infectious diseases, 1997, Volume: 176, Issue:1

    Topics: Acute Disease; Acyclovir; Adolescent; Adult; Antiviral Agents; Arabinofuranosyluracil; Double-Blind Method; Herpes Zoster; HIV Infections; Humans; Middle Aged; Patient Compliance

1997
Sorivudine versus acyclovir for treatment of dermatomal herpes zoster in human immunodeficiency virus-infected patients: results from a randomized, controlled clinical trial. Collaborative Antiviral Study Group/AIDS Clinical Trials Group, Herpes Zoster St
    Antimicrobial agents and chemotherapy, 1998, Volume: 42, Issue:5

    Topics: Acyclovir; Adolescent; Adult; Aged; AIDS-Related Opportunistic Infections; Antiviral Agents; Arabinofuranosyluracil; Double-Blind Method; Female; Herpes Zoster; Humans; Male; Middle Aged; Quality of Life; Recurrence; Treatment Outcome

1998

Other Studies

69 other study(ies) available for arabinofuranosyluracil and sorivudine

ArticleYear
Structure-activity relationship between (E)-5-(2-bromovinyl)- and 5-vinyl-1-beta-D-arabinofuranosyluracil (BV-araU, V-araU) in inhibition of Epstein-Barr virus replication.
    Antiviral research, 1992, Volume: 17, Issue:1

    Topics: Antiviral Agents; Arabinofuranosyluracil; Burkitt Lymphoma; DNA, Viral; Dose-Response Relationship, Drug; Herpesvirus 4, Human; Humans; Peptides; Structure-Activity Relationship; Tumor Cells, Cultured; Viral Proteins; Virus Replication

1992
Oral bioavailability and anti-simian varicella virus efficacy of 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil (BV-araU) in monkeys.
    The Journal of infectious diseases, 1992, Volume: 165, Issue:4

    Topics: Administration, Oral; Adsorption; Animals; Antiviral Agents; Arabinofuranosyluracil; Biological Availability; Cells, Cultured; Chickenpox; Chlorocebus aethiops; Dose-Response Relationship, Drug; Female; Herpesvirus 3, Human; Male

1992
In vitro drug combination of 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil with anti-human immunodeficiency virus or anticancer nucleosides.
    Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:1

    Topics: Antiviral Agents; Arabinofuranosyluracil; Bromouracil; Cytarabine; Drug Combinations; Floxuridine; Fluorouracil; Herpesvirus 3, Human; HIV-1; Humans; Zidovudine

1992
Comparison of antiviral assay methods using cell-free and cell-associated varicella-zoster virus.
    Antiviral research, 1992, Volume: 18, Issue:2

    Topics: Acyclovir; Antiviral Agents; Arabinofuranosyluracil; Cell-Free System; DNA Replication; DNA, Viral; Herpesvirus 3, Human; Humans; Nucleic Acid Hybridization; Viral Plaque Assay; Virus Replication

1992
Analysis of toxic and mutagenic activities of antiherpesvirus nucleosides against HeLa cells and herpes simplex virus type 1.
    Mutation research, 1992, Volume: 267, Issue:1

    Topics: Acyclovir; Antiviral Agents; Arabinofuranosyluracil; Bromodeoxyuridine; Cell Death; Cell Division; HeLa Cells; Humans; Mutagens; Nucleosides; Simplexvirus; Vidarabine; Virus Replication

1992
A radioimmunoassay for the new antiviral agent 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil.
    Therapeutic drug monitoring, 1992, Volume: 14, Issue:6

    Topics: Antiviral Agents; Arabinofuranosyluracil; Cross Reactions; Dose-Response Relationship, Drug; Humans; Indicators and Reagents; Isotope Labeling; Male; Radioimmunoassay; Reference Standards; Sensitivity and Specificity

1992
Efficacy of oral treatment with BV-araU against cutaneous infection with herpes simplex type 1 in shaved mice.
    Antiviral research, 1992, Volume: 17, Issue:2

    Topics: Acyclovir; Administration, Oral; Animals; Antiviral Agents; Arabinofuranosyluracil; Disease Models, Animal; Drug Administration Schedule; Drug Evaluation, Preclinical; Female; Herpes Simplex; Immune Tolerance; Male; Mice; Mice, Inbred BALB C

1992
Inhibition of DNA synthesis in varicella-zoster virus-infected cells by BV-araU.
    Microbiology and immunology, 1991, Volume: 35, Issue:2

    Topics: Acyclovir; Antiviral Agents; Arabinofuranosyluracil; Cell Line; DNA, Viral; Dose-Response Relationship, Drug; Fibroblasts; Herpesvirus 3, Human; Humans; Lung; Simplexvirus; Thymidine

1991
Susceptibility of a herpes simplex virus ribonucleotide reductase null mutant to deoxyribonucleosides and antiviral nucleoside analogs.
    Microbiology and immunology, 1991, Volume: 35, Issue:8

    Topics: Acyclovir; Arabinofuranosyluracil; Deoxyribonucleosides; Ganciclovir; Hydroxyurea; Mutation; Nucleic Acid Synthesis Inhibitors; Ribonucleotide Reductases; Simplexvirus

1991
Different antiviral potencies of BV-araU and related nucleoside analogues against herpes simplex virus type 1 in human cell lines and Vero cells.
    Microbiology and immunology, 1991, Volume: 35, Issue:11

    Topics: Aminopterin; Animals; Antiviral Agents; Arabinofuranosyluracil; Cell Line; Drug Interactions; Floxuridine; Humans; Nucleosides; Simplexvirus; Thymidine; Vero Cells

1991
High-performance liquid chromatographic determination of 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil and its metabolite (E)-5-(2-bromovinyl)uracil in serum.
    Journal of chromatography, 1991, Aug-23, Volume: 568, Issue:2

    Topics: Antiviral Agents; Arabinofuranosyluracil; Chromatography, High Pressure Liquid; Humans; Reproducibility of Results; Spectrophotometry, Ultraviolet

1991
Analysis of mutations in the thymidine kinase genes of drug-resistant varicella-zoster virus populations using the polymerase chain reaction.
    The Journal of general virology, 1991, Volume: 72 ( Pt 3)

    Topics: Amino Acid Sequence; Animals; Antiviral Agents; Arabinofuranosyluracil; Base Sequence; Cell Line; Cloning, Molecular; DNA, Viral; Drug Resistance, Microbial; Electrophoresis, Polyacrylamide Gel; Herpesvirus 3, Human; Humans; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Thymidine Kinase; Vero Cells

1991
Brovavir: its antiherpesviral activity and mode of action.
    Advances in experimental medicine and biology, 1990, Volume: 278

    Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; DNA, Viral; Herpes Simplex; Herpesviridae Infections; Herpesvirus 3, Human; Immunosuppression Therapy; Mice; Mice, Inbred BALB C; Phosphorylation; Simplexvirus; Thymidine Kinase

1990
Effect of 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil against herpes simplex virus type 1 infection in immunosuppressed mice.
    Antimicrobial agents and chemotherapy, 1990, Volume: 34, Issue:12

    Topics: Acyclovir; Animals; Antiviral Agents; Arabinofuranosyluracil; Cyclophosphamide; Herpes Simplex; Immunosuppression Therapy; Male; Mice; Mice, Inbred ICR; Simplexvirus; Virus Replication

1990
Antiviral potencies of BV-araU and related nucleoside analogues against varicella-zoster virus in different cell lines.
    Microbiology and immunology, 1990, Volume: 34, Issue:11

    Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Herpesvirus 3, Human; Humans; Tumor Cells, Cultured; Vero Cells

1990
Effect of 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil (brovavir) on experimental infections in mice with herpes simplex virus type 1 strains of different degrees of virulence.
    Antimicrobial agents and chemotherapy, 1990, Volume: 34, Issue:5

    Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Brain; Encephalitis; Herpes Simplex; Male; Mice; Mice, Inbred ICR; Simplexvirus; Uridine; Virus Replication

1990
Drug susceptibilities of isolates of varicella-zoster virus in a clinical study of oral brovavir.
    Microbiology and immunology, 1990, Volume: 34, Issue:4

    Topics: Acyclovir; Adult; Antiviral Agents; Arabinofuranosyluracil; Cell Line; Herpes Zoster; Herpesvirus 3, Human; Humans; Uridine

1990
Comparison of antiviral efficacies of 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil (brovavir) and acyclovir against herpes simplex virus type 1 infections in mice.
    Antiviral research, 1990, Volume: 14, Issue:2

    Topics: Acyclovir; Animals; Antiviral Agents; Arabinofuranosyluracil; Disease Models, Animal; Drug Administration Routes; Encephalitis; Herpes Simplex; Humans; Male; Mice; Simplexvirus; Survival Rate

1990
Mechanism of selective inhibition of varicella zoster virus replication by 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil.
    Molecular pharmacology, 1989, Volume: 36, Issue:2

    Topics: Antiviral Agents; Arabinofuranosyluracil; Biological Transport; Cells, Cultured; DNA; DNA-Directed DNA Polymerase; DNA, Viral; Dose-Response Relationship, Drug; Herpesvirus 3, Human; Humans; In Vitro Techniques; Kinetics; Thymidine Kinase; Uridine; Virus Replication

1989
Effects of various nucleosides on antiviral activity and metabolism of 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil against herpes simplex virus types 1 and 2.
    Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:10

    Topics: Antiviral Agents; Arabinofuranosyluracil; Chromatography, High Pressure Liquid; Nucleosides; Phosphorylation; Simplexvirus; Uridine

1988
Efficacies of antiherpesvirus nucleosides against two strains of herpes simplex virus type 1 in Vero and human embryo lung fibroblast cells.
    Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:7

    Topics: Acyclovir; Aminopterin; Animals; Antiviral Agents; Arabinofuranosyluracil; Arabinonucleosides; Dose-Response Relationship, Drug; Fibroblasts; Humans; Idoxuridine; Lung; Nucleosides; Simplexvirus; Thymidine; Vero Cells; Vidarabine

1988
Comparison of two bromovinyl nucleoside analogs, 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil and E-5-(2-bromovinyl)-2'-deoxyuridine, with acyclovir in inhibition of Epstein-Barr virus replication.
    Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:7

    Topics: Acyclovir; Arabinofuranosyluracil; Bromodeoxyuridine; DNA, Viral; Dose-Response Relationship, Drug; Drug Combinations; Herpesvirus 4, Human; Peptide Biosynthesis; Uridine; Virus Replication

1988
Effect of (E)-5-(2-bromovinyl)- and 5-vinyl-1-beta-D-arabinofuranosyluracil on Epstein-Barr virus antigen expression in P3HR-1 cells: comparison with acyclovir.
    Acta virologica, 1987, Volume: 31, Issue:1

    Topics: Acyclovir; Antigens, Viral; Antiviral Agents; Arabinofuranosyluracil; Capsid Proteins; Cell Line; Herpesvirus 4, Human; Humans; Uridine

1987
Efficacy of (E)-5-(2-bromovinyl)- and 5-vinyl-1-beta-D-arabinofuranosyluracil against acute herpes simplex virus keratitis and the establishment of latency: comparison with acyclovir and bromovinyldeoxyuridine.
    Acta virologica, 1987, Volume: 31, Issue:4

    Topics: Acute Disease; Acyclovir; Animals; Antiviral Agents; Arabinofuranosyluracil; Bromodeoxyuridine; Chemical Phenomena; Chemistry; Keratitis, Dendritic; Rabbits; Simplexvirus; Uridine

1987
Treatment of experimental herpes simplex virus type 1 encephalitis in mice with (E)-5-(2-bromovinyl)- and 5-vinyl-1-beta-D-arabinofuranosyluracil: comparison with bromovinyl-deoxyuridine and acyclovir.
    Antiviral research, 1986, Volume: 6, Issue:2

    Topics: Acyclovir; Animals; Arabinofuranosyluracil; Bromodeoxyuridine; Cells, Cultured; Encephalitis; Female; Foscarnet; Herpes Simplex; Humans; Mice; Phosphonoacetic Acid; Simplexvirus; Uridine; Viral Plaque Assay

1986
Antiviral activity of various 1-beta-D-arabinofuranosyl-E-5-halogenovinyluracils and E-5-bromovinyl-2'-deoxyuridine against salmon herpes virus, Oncorhynchus masou virus (OMV).
    Antiviral research, 1987, Volume: 7, Issue:2

    Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Bromodeoxyuridine; Cell Line; Chromatography, High Pressure Liquid; DNA Polymerase II; Fish Diseases; Herpesviridae; Herpesviridae Infections; Nucleic Acid Synthesis Inhibitors; Salmon; Uridine

1987
Evaluation of (E)-5-(2-bromovinyl)- and 5-vinyl-1-beta-D-arabinofuranosyluracil (BrVaraU, VaraU) in the treatment of experimental herpes simplex virus type 1 keratitis in rabbits: comparison with (E)-5-(2-bromovinyl)-2'-deoxyuridine (BrVUdR).
    Antiviral research, 1988, Volume: 9, Issue:4

    Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Bromodeoxyuridine; Drug Evaluation, Preclinical; Keratitis, Dendritic; Ophthalmic Solutions; Rabbits

1988
Comparative metabolism of E-5-(2-bromovinyl)-2'-deoxyuridine and 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil in herpes simplex virus-infected cells.
    Molecular pharmacology, 1987, Volume: 31, Issue:4

    Topics: Arabinofuranosyluracil; Bromodeoxyuridine; Cell Line; Chromatography, High Pressure Liquid; Fibroblasts; Herpes Simplex; Humans; Osteosarcoma; Uridine

1987
In vitro and in vivo antiviral activity of 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil (BV-araU) and related compounds.
    Antiviral research, 1984, Volume: 4, Issue:3

    Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Encephalitis; Herpes Simplex; Male; Mice; Simplexvirus; Uridine

1984
Investigation of antiviral activity of 1-beta-D-arabinofuranosylthymine (ara-T) and 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil (BV-ara-U) in monkeys infected with simian varicella virus.
    Antiviral research, 1984, Volume: 4, Issue:5

    Topics: Animals; Arabinofuranosyluracil; Arabinonucleosides; Chickenpox; Chlorocebus aethiops; Herpesviridae Infections; Nervous System; Neurons; Thymidine; Uridine

1984
Antiherpesviral and anticellular effects of 1-beta-D-arabinofuranosyl-E-5-(2-halogenovinyl) uracils.
    Antimicrobial agents and chemotherapy, 1981, Volume: 20, Issue:1

    Topics: Antiviral Agents; Arabinofuranosyluracil; Cell Division; Cell Line; Cells, Cultured; Cytopathogenic Effect, Viral; DNA, Viral; Simplexvirus; Uridine; Virus Replication

1981
Strains of varicella-zoster virus resistant to 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil.
    Antimicrobial agents and chemotherapy, 1984, Volume: 25, Issue:6

    Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Chlorocebus aethiops; Cloning, Molecular; DNA, Viral; Drug Resistance, Microbial; Embryo, Mammalian; Fibroblasts; Guinea Pigs; Herpesvirus 3, Human; Kidney; Thymidine; Thymidine Kinase; Uridine; Viral Plaque Assay; Virus Cultivation

1984
Successful treatment of sorivudine-related agranulocytosis with granulocyte-colony stimulating factor.
    American journal of hematology, 1995, Volume: 50, Issue:3

    Topics: Aged; Agranulocytosis; Antimetabolites, Antineoplastic; Antiviral Agents; Arabinofuranosyluracil; Female; Fluorouracil; Granulocyte Colony-Stimulating Factor; Humans; Male; Middle Aged

1995
Sorivudine (BV-ara-U) for the treatment of complicated refractory varicella zoster virus infection in HIV-infected patients.
    AIDS (London, England), 1995, Volume: 9, Issue:7

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Arabinofuranosyluracil; Chickenpox; Drug Resistance; Herpesvirus 3, Human; Humans; Male

1995
Construction of a herpes simplex virus/varicella-zoster virus (HSV/VZV) thymidine kinase recombinant with the pathogenic potential of HSV and a drug sensitivity profile resembling that of VZV.
    The Journal of general virology, 1995, Volume: 76 ( Pt 8)

    Topics: Acyclovir; Animals; Antiviral Agents; Arabinofuranosyluracil; Base Sequence; Cytomegalovirus; Drug Evaluation, Preclinical; Ganciclovir; Herpes Simplex; Herpesvirus 1, Human; Herpesvirus 3, Human; Humans; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Promoter Regions, Genetic; Thymidine Kinase; Transformation, Genetic; Virulence; Virus Latency

1995
Treatment of progressive outer retinal necrosis with sorivudine.
    American journal of ophthalmology, 1995, Volume: 119, Issue:4

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Arabinofuranosyluracil; Drug Therapy, Combination; Ganciclovir; Herpes Zoster Ophthalmicus; Humans; Male; Middle Aged; Retinal Necrosis Syndrome, Acute

1995
In vitro and in vivo anti-herpes viral activities and biological properties of CV-araU.
    Antiviral research, 1994, Volume: 25, Issue:3-4

    Topics: 3T3 Cells; Animals; Antiviral Agents; Arabinofuranosyluracil; Bromine; Cell Line; Chlorine; Encephalitis, Viral; Herpes Simplex; Humans; Male; Mice; Rats

1994
Retinal toxicity and ocular kinetics of 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil in rabbits.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 1994, Volume: 232, Issue:8

    Topics: Administration, Oral; Animals; Antiviral Agents; Arabinofuranosyluracil; Electroretinography; Eye; Half-Life; Injections; Rabbits; Retina

1994
[Prevention of drug interactions and its countermeasure].
    The Journal of toxicological sciences, 1994, Volume: 19, Issue:3

    Topics: Animals; Arabinofuranosyluracil; Drug Interactions; Fluorouracil; Humans; Rats; Tegafur; Uracil

1994
Deaths bring clinical trials under scrutiny in Japan.
    Nature, 1994, Jun-30, Volume: 369, Issue:6483

    Topics: Antiviral Agents; Arabinofuranosyluracil; Clinical Trials as Topic; Government Regulation; Humans; Japan; Poisoning; Professional Misconduct; Research Subjects; Therapeutic Human Experimentation

1994
Effect of BV-araU and acyclovir on varicella-zoster virus replication with various length and timing of drug exposure.
    Microbiology and immunology, 1994, Volume: 38, Issue:2

    Topics: Acyclovir; Antiviral Agents; Arabinofuranosyluracil; Cell Line; Cytopathogenic Effect, Viral; Dose-Response Relationship, Drug; Herpesvirus 3, Human; Humans; Time Factors; Viral Plaque Assay; Virus Replication

1994
Blaming somebody else.
    Nature, 1994, Sep-08, Volume: 371, Issue:6493

    Topics: Antiviral Agents; Arabinofuranosyluracil; Drug Approval; Government Agencies; Herpes Zoster; Humans; Japan; Social Responsibility

1994
Mechanism of inhibition of DNA synthesis by 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil.
    Microbiology and immunology, 1993, Volume: 37, Issue:6

    Topics: Antiviral Agents; Arabinofuranosyluracil; Dideoxynucleotides; DNA Polymerase I; DNA, Bacterial; Escherichia coli; Thymine Nucleotides

1993
Metabolism of 5'-ether prodrugs of 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil in rats.
    Biochemical pharmacology, 1993, Dec-14, Volume: 46, Issue:12

    Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Biotransformation; Germ-Free Life; Klebsiella pneumoniae; Male; Prodrugs; Rats; Rats, Sprague-Dawley

1993
Antiviral activity of 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil against thymidine kinase negative strains of varicella-zoster virus.
    Microbiology and immunology, 1993, Volume: 37, Issue:11

    Topics: Antiviral Agents; Arabinofuranosyluracil; Cells, Cultured; Herpesvirus 3, Human; Humans; Thymidine Kinase; Thymidylate Synthase

1993
Analysis of the thymidine kinase genes from acyclovir-resistant mutants of varicella-zoster virus isolated from patients with AIDS.
    Journal of virology, 1993, Volume: 67, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Acyclovir; AIDS-Related Opportunistic Infections; Amino Acid Sequence; Antiviral Agents; Arabinofuranosyluracil; Base Sequence; Drug Resistance, Microbial; Genes, Viral; Genetic Variation; Guanine; Herpesviridae Infections; Herpesvirus 3, Human; Humans; Molecular Sequence Data; Mutagenesis; Precipitin Tests; Sequence Analysis; Sequence Homology, Amino Acid; Thymidine Kinase; Viral Plaque Assay

1993
Topical treatment with BV-araU of immunosuppressed and immunocompetent shaved mice cutaneously infected with herpes simplex virus type 1.
    Antiviral research, 1993, Volume: 21, Issue:1

    Topics: Administration, Topical; Animals; Antiviral Agents; Arabinofuranosyluracil; Cyclophosphamide; Dose-Response Relationship, Drug; Herpes Simplex; Immune Tolerance; Immunocompetence; Immunocompromised Host; Male; Mice; Mice, Inbred BALB C; Simplexvirus; Skin Diseases, Viral; Time Factors

1993
Outer retinal necrosis due to a strain of varicella-zoster virus resistant to acyclovir, ganciclovir, and sorivudine.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1996, Volume: 22, Issue:5

    Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Arabinofuranosyluracil; Chickenpox; Drug Resistance, Microbial; Female; Ganciclovir; Herpesvirus 3, Human; Humans; Retinal Necrosis Syndrome, Acute

1996
Analysis of phosphorylation pathways of antiherpesvirus nucleosides by varicella-zoster virus-specific enzymes.
    Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:4

    Topics: Acyclovir; Antiviral Agents; Arabinofuranosyluracil; Cell Division; Cell Line; Cytomegalovirus; Ganciclovir; Guanine; Herpesviridae; Herpesvirus 3, Human; Humans

1996
Leukopenia-inducing effect of a combination of a new 5-fluorouracil (5-FU)-derived drug, BOF-A2 (emitefur), with other 5-FU-derived drugs or BV-araU (sorivudine) in rats.
    Japanese journal of pharmacology, 1996, Volume: 70, Issue:2

    Topics: Animals; Antineoplastic Agents; Antiviral Agents; Arabinofuranosyluracil; Dose-Response Relationship, Drug; Drug Combinations; Fluorouracil; Leukopenia; Male; Rats; Rats, Sprague-Dawley

1996
Lethal drug interactions of sorivudine, a new antiviral drug, with oral 5-fluorouracil prodrugs.
    Drug metabolism and disposition: the biological fate of chemicals, 1997, Volume: 25, Issue:2

    Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Antiviral Agents; Arabinofuranosyluracil; Area Under Curve; Bone Marrow Diseases; Bromouracil; Dihydrouracil Dehydrogenase (NADP); Drug Synergism; Female; Intestine, Small; Liver; Oxidoreductases; Rats; Rats, Wistar; Tegafur; Tissue Distribution

1997
Strategic proposals for predicting drug-drug interactions during new drug development: based on sixteen deaths caused by interactions of the new antiviral sorivudine with 5-fluorouracil prodrugs.
    The Journal of toxicological sciences, 1996, Volume: 21, Issue:5

    Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Drug Design; Drug Interactions; Drug Therapy, Combination; Fluorouracil; Herpes Zoster; Humans; Japan; Prodrugs; Rats; Risk Assessment

1996
Intestinal anaerobic bacteria hydrolyse sorivudine, producing the high blood concentration of 5-(E)-(2-bromovinyl)uracil that increases the level and toxicity of 5-fluorouracil.
    Pharmacogenetics, 1997, Volume: 7, Issue:1

    Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Bacteria, Anaerobic; Bacteroides; Biotransformation; Bromouracil; Cecum; Fluorouracil; Gastric Mucosa; Gastrointestinal Contents; Intestinal Mucosa; Kidney; Liver; Male; Organ Specificity; Pentosyltransferases; Pyrimidine Phosphorylases; Rats; Rats, Sprague-Dawley

1997
Lethal drug interactions of sorivudine, a new antiviral drug, with oral 5-fluorouracil prodrugs.
    Drug metabolism and disposition: the biological fate of chemicals, 1997, Volume: 25, Issue:5

    Topics: Animals; Antimetabolites, Antineoplastic; Antiviral Agents; Arabinofuranosyluracil; Colony-Forming Units Assay; Dihydropyridines; Female; Oxidoreductases; Rats; Rats, Wistar; Tegafur; Tissue Distribution

1997
Suicidal inactivation of human dihydropyrimidine dehydrogenase by (E)-5-(2-bromovinyl)uracil derived from the antiviral, sorivudine.
    Cancer letters, 1998, Jan-09, Volume: 122, Issue:1-2

    Topics: Antiviral Agents; Arabinofuranosyluracil; Bromouracil; Dihydrouracil Dehydrogenase (NADP); Dose-Response Relationship, Drug; Humans; Oxidoreductases; Recombinant Proteins

1998
Metabolic fate of [3H]1-beta-D-arabinofuranosyl-5-[(E)-2-bromovinyl]uracil in herpes simplex virus type 1-infected cells.
    Microbiology and immunology, 1997, Volume: 41, Issue:12

    Topics: Acyclovir; Antiviral Agents; Arabinofuranosyluracil; Cell Line; Centrifugation, Density Gradient; Chromatography, High Pressure Liquid; Deoxyribonucleases; DNA, Viral; Herpesvirus 1, Human; Humans; Oligodeoxyribonucleotides; Thymidine; Tritium

1997
Sorivudine and 5-fluorouracil; a clinically significant drug-drug interaction due to inhibition of dihydropyrimidine dehydrogenase.
    British journal of clinical pharmacology, 1998, Volume: 46, Issue:1

    Topics: Antimetabolites, Antineoplastic; Antiviral Agents; Arabinofuranosyluracil; Dihydrouracil Dehydrogenase (NADP); Drug Interactions; Fluorouracil; Humans; Oxidoreductases

1998
Chronic varicella-zoster virus epithelial keratitis in patients with acquired immunodeficiency syndrome.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1998, Volume: 116, Issue:8

    Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Adult; Aged; Antiviral Agents; Arabinofuranosyluracil; CD4 Lymphocyte Count; Chronic Disease; Epithelium, Corneal; Herpes Zoster Ophthalmicus; Herpesvirus 3, Human; Humans; Keratitis, Dendritic; Male; Middle Aged; Retrospective Studies

1998
A possible mechanism of eighteen patient deaths caused by interactions of sorivudine, a new antiviral drug, with oral 5-fluorouracil prodrugs.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 287, Issue:2

    Topics: Animals; Antimetabolites, Antineoplastic; Antiviral Agents; Arabinofuranosyluracil; Bromouracil; Cause of Death; Dihydrouracil Dehydrogenase (NADP); Drug Interactions; Fluorouracil; Half-Life; Herpes Zoster; Humans; Liver; Neoplasms; Oxidoreductases; Prodrugs; Rats; Tissue Distribution

1998
Failure of sorivudine therapy in progressive outer retinal necrosis caused by varicella zoster virus.
    Australian and New Zealand journal of ophthalmology, 1998, Volume: 26, Issue:4

    Topics: Adult; AIDS-Related Opportunistic Infections; Antibodies, Viral; Antiviral Agents; Arabinofuranosyluracil; Blindness; DNA, Viral; Drug Therapy, Combination; Female; Follow-Up Studies; Herpes Zoster Ophthalmicus; Herpesvirus 3, Human; Humans; Recurrence; Retinal Necrosis Syndrome, Acute; Treatment Failure

1998
Comparative in vitro and in vivo cytotoxic activity of (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU) and its arabinosyl derivative, (E)-5-(2-bromovinyl)-1-beta-D-arabinofuranosyluracil (BVaraU), against tumor cells expressing either the Varicella zoster or
    Cancer gene therapy, 2000, Volume: 7, Issue:2

    Topics: Animals; Antineoplastic Agents; Antiviral Agents; Arabinofuranosyluracil; Breast Neoplasms; Bromodeoxyuridine; Female; Genetic Vectors; Herpesvirus 3, Human; Humans; Male; Mice; Mice, Nude; Rats; Rats, Inbred F344; Simplexvirus; Thymidine Kinase; Tumor Cells, Cultured

2000
The need for improving information systems on drug interactions in Japan.
    Archives of internal medicine, 2000, Jul-10, Volume: 160, Issue:13

    Topics: Adverse Drug Reaction Reporting Systems; Antimetabolites, Antineoplastic; Antiviral Agents; Arabinofuranosyluracil; Drug Interactions; Fluorouracil; Humans; Japan; Polypharmacy

2000
Effects of light intensity, n-alcohols, water-soluble colorants, and solution viscosity on photoisomerization of sorivudine.
    Pharmaceutical development and technology, 2001, Volume: 6, Issue:1

    Topics: Alcohols; Antiviral Agents; Arabinofuranosyluracil; Coloring Agents; Isomerism; Light; Photochemistry; Solubility; Viscosity

2001
2'-O-Acyl/alkyl-substituted arabinosyl nucleosides as inhibitors of human mitochondrial thymidine kinase.
    Biochemical pharmacology, 2001, Mar-15, Volume: 61, Issue:6

    Topics: Adenosine Triphosphate; Antineoplastic Agents; Antiviral Agents; Arabinofuranosyluracil; Arabinonucleosides; Binding, Competitive; Humans; Kinetics; Mitochondria; Phosphorus Radioisotopes; Phosphorylation; Thymidine; Thymidine Kinase; Tritium

2001
Herpesviruses.
    BETA : bulletin of experimental treatments for AIDS : a publication of the San Francisco AIDS Foundation, 1995

    Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Arabinofuranosyluracil; Cidofovir; Complementary Therapies; Cytosine; Famciclovir; Foscarnet; Herpesviridae Infections; Organophosphonates; Organophosphorus Compounds; Valacyclovir; Valine; Viral Vaccines

1995
In vitro selection of drug-resistant varicella-zoster virus (VZV) mutants (OKA strain): differences between acyclovir and penciclovir?
    Antiviral research, 2004, Volume: 61, Issue:3

    Topics: 2-Aminopurine; Acyclovir; Adenine; Antiviral Agents; Arabinofuranosyluracil; Bromodeoxyuridine; Cidofovir; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Multiple, Viral; Drug Resistance, Viral; Foscarnet; Guanine; Herpesvirus 3, Human; Humans; Microbial Sensitivity Tests; Mutation; Organophosphonates; Phenotype; Selection, Genetic; Thymidine Kinase; Viral Proteins

2004
Drug interaction ontology (DIO) for inferences of possible drug-drug interactions.
    Studies in health technology and informatics, 2004, Volume: 107, Issue:Pt 1

    Topics: Arabinofuranosyluracil; Artificial Intelligence; Computational Biology; Dihydrouracil Dehydrogenase (NADP); Drug Interactions; Fluorouracil; Humans; Vocabulary, Controlled

2004
The human genome: its modifications and interactions with those of the microbiome, and the practice of genomic medicine.
    Discovery medicine, 2013, Volume: 15, Issue:84

    Topics: Arabinofuranosyluracil; Genome, Human; Genomics; Humans; Metagenome; Mitochondrial Diseases

2013
Spectrum of activity and mechanisms of resistance of various nucleoside derivatives against gammaherpesviruses.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:12

    Topics: Acyclovir; Amino Acid Sequence; Animals; Antiviral Agents; Arabinofuranosyluracil; Bromodeoxyuridine; Cytarabine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Guanine; Herpesvirus 4, Human; Herpesvirus 8, Human; Humans; Molecular Sequence Data; Protein Kinases; Rhadinovirus; Sequence Alignment; Structure-Activity Relationship; Thymidine Kinase; Viral Proteins

2014