arabinofuranosyluracil and 5-propynylarabinofuranosyluracil

arabinofuranosyluracil has been researched along with 5-propynylarabinofuranosyluracil in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's18 (90.00)18.2507
2000's2 (10.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Honess, RW; Lacey, SF; Powell, KL; Purifoy, DJ; Suzutani, T1
Nikkels, AF; Piérard, GE1
Bevilacqua, F; Collins, P; Darby, G; Davis-Poynter, N; Gower, D; Worrallo, J1
Crome, P; Holdich, TA; Peck, RW; Posner, J; Weatherley, BC; Wootton, R1
Jackson, SH; Lee, DR; Peck, RW; Posner, J; Wootton, R1
Easterbrook, P; Wood, MJ1
Buick, AR; Cooper, JD; Sheung, CT1
Darby, G1
Beauchamp, LM; Darby, G; de Miranda, P; Ertl, P; Krenitsky, TA; Lacey, S; Powell, KL; Purifoy, DJ; Rahim, SG; Roberts, G1
Bannister, B; Crooks, RJ; Mandal, BK; McKendrick, MW; Peck, RW; Wood, MJ1
Buick, AR; Sheung, CT1
Callaghan, J; Crome, P; Fraser, I; Frick, L; Peck, R; Posner, J; Wiggs, R; Wootton, R1
Bidault, R; Chretien, P; Fillastre, JP; Gillotin, C; Godin, M; Legallicier, B; Peck, RW; Posner, J; Wooton, R1
Bidault, R; Fillastre, JP; Godin, M; Le Roy, F; Legallicler, B; Peck, RW; Posner, J1
Fiddian, AP1
Bannister, B; Crome, P; Crooks, RJ; Mandal, BK; McKendrick, MW; Peck, RW; Wood, MJ1
Andersen, PL; Diaz Perez, JL; Fiddian, AP; Lucht, RF; McKendrick, MW; Shukla, S; Söltz-Szöts, J; Tyring, S1
Lowe, D; McGuigan, C; Miller, W; Perry, A; Rahim, SG; Slater, MJ; Sutton, PW; Yarnold, CJ1
Wareham, D2

Reviews

7 review(s) available for arabinofuranosyluracil and 5-propynylarabinofuranosyluracil

ArticleYear
Recognition and treatment of shingles.
    Drugs, 1994, Volume: 48, Issue:4

    Topics: Acyclovir; Adjuvants, Immunologic; Adrenal Cortex Hormones; Antiviral Agents; Arabinofuranosyluracil; Chickenpox; Herpes Zoster; Humans; Immunoglobulins; Virus Replication

1994
Successors to acyclovir.
    The Journal of antimicrobial chemotherapy, 1994, Volume: 34, Issue:3

    Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Arabinofuranosyluracil; Chickenpox; Drug Resistance, Microbial; Famciclovir; Herpes Simplex; Herpes Zoster; Humans; Valacyclovir; Valine

1994
Acyclovir--and beyond.
    The Journal of international medical research, 1994, Volume: 22 Suppl 1

    Topics: Acyclovir; Arabinofuranosyluracil; Cytomegalovirus Infections; Ganciclovir; Guanine; Herpes Simplex; Herpesvirus 3, Human; Humans; Valacyclovir; Valine

1994
Review of research leading to new anti-herpesvirus agents in clinical development: valaciclovir hydrochloride (256U, the L-valyl ester of acyclovir) and 882C, a specific agent for varicella zoster virus.
    Journal of medical virology, 1993, Volume: Suppl 1

    Topics: Acyclovir; Antiviral Agents; Arabinofuranosyluracil; Drug Design; Herpesvirus 3, Human; Prodrugs; Valacyclovir; Valine

1993
Antiviral drugs in development for herpes zoster.
    Scandinavian journal of infectious diseases. Supplementum, 1996, Volume: 100

    Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Arabinofuranosyluracil; Controlled Clinical Trials as Topic; Drug Approval; Famciclovir; Herpes Zoster; Humans; Prodrugs; Treatment Outcome; United States; Valacyclovir; Valine

1996
Postherpetic neuralgia.
    Clinical evidence, 2004, Issue:12

    Topics: 2-Aminopurine; Acyclovir; Amines; Antidepressive Agents, Tricyclic; Antiviral Agents; Arabinofuranosyluracil; Cyclohexanecarboxylic Acids; Famciclovir; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Neuralgia; Valacyclovir; Valine

2004
Postherpetic neuralgia.
    Clinical evidence, 2005, Issue:14

    Topics: 2-Aminopurine; Acyclovir; Amines; Antidepressive Agents, Tricyclic; Antiviral Agents; Arabinofuranosyluracil; Cyclohexanecarboxylic Acids; Famciclovir; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia, Postherpetic; Valacyclovir; Valine

2005

Trials

6 trial(s) available for arabinofuranosyluracil and 5-propynylarabinofuranosyluracil

ArticleYear
Pharmacokinetics and tolerability of single oral doses of 882C87, a potent, new anti-varicella-zoster virus agent, in healthy volunteers.
    Antimicrobial agents and chemotherapy, 1995, Volume: 39, Issue:1

    Topics: Administration, Oral; Adult; Aged; Aging; Antiviral Agents; Arabinofuranosyluracil; Chromatography, High Pressure Liquid; Fasting; Herpesvirus 3, Human; Humans; Male; Single-Blind Method

1995
The bioavailability and disposition of 1-(beta-D-arabinofuranosyl)-5-(1-propynyl)uracil (882C87), a potent, new anti-varicella zoster virus agent.
    British journal of clinical pharmacology, 1995, Volume: 39, Issue:2

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antiviral Agents; Arabinofuranosyluracil; Biological Availability; Female; Herpesvirus 3, Human; Humans; Male

1995
Inhibition of dihydropyrimidine dehydrogenase by 5-propynyluracil, a metabolite of the anti-varicella zoster virus agent netivudine.
    Clinical pharmacology and therapeutics, 1996, Volume: 59, Issue:1

    Topics: Aged; Alkynes; Antiviral Agents; Arabinofuranosyluracil; Dihydrouracil Dehydrogenase (NADP); Dose-Response Relationship, Drug; Herpesvirus 3, Human; Humans; Oxidoreductases; Uracil

1996
Pharmacokinetics of netivudine, a potent anti-varicella zoster virus drug, in patients with renal impairment.
    The Journal of antimicrobial chemotherapy, 1996, Volume: 37, Issue:5

    Topics: Administration, Oral; Aged; Antiviral Agents; Arabinofuranosyluracil; Blood Proteins; Creatinine; Herpesvirus 3, Human; Humans; Male; Middle Aged; Renal Insufficiency

1996
Multiple dose netivudine, a potent anti-varicella zoster virus agent, in healthy elderly volunteers and patients with shingles.
    The Journal of antimicrobial chemotherapy, 1996, Volume: 37, Issue:3

    Topics: Aged; Aged, 80 and over; Antiviral Agents; Arabinofuranosyluracil; Drug Administration Schedule; Female; Herpes Zoster; Herpesvirus 3, Human; Humans; Male; Middle Aged; Patient Compliance

1996
A randomized controlled trial of acyclovir versus netivudine for treatment of herpes zoster. International Zoster Study Group.
    The Journal of antimicrobial chemotherapy, 1998, Volume: 41, Issue:5

    Topics: Acyclovir; Aged; Antiviral Agents; Arabinofuranosyluracil; Double-Blind Method; Drug Administration Schedule; Exanthema; Female; Herpes Zoster; Humans; Male; Middle Aged; Pain; Prognosis

1998

Other Studies

7 other study(ies) available for arabinofuranosyluracil and 5-propynylarabinofuranosyluracil

ArticleYear
Analysis of mutations in the thymidine kinase genes of drug-resistant varicella-zoster virus populations using the polymerase chain reaction.
    The Journal of general virology, 1991, Volume: 72 ( Pt 3)

    Topics: Amino Acid Sequence; Animals; Antiviral Agents; Arabinofuranosyluracil; Base Sequence; Cell Line; Cloning, Molecular; DNA, Viral; Drug Resistance, Microbial; Electrophoresis, Polyacrylamide Gel; Herpesvirus 3, Human; Humans; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Thymidine Kinase; Vero Cells

1991
Construction of a herpes simplex virus/varicella-zoster virus (HSV/VZV) thymidine kinase recombinant with the pathogenic potential of HSV and a drug sensitivity profile resembling that of VZV.
    The Journal of general virology, 1995, Volume: 76 ( Pt 8)

    Topics: Acyclovir; Animals; Antiviral Agents; Arabinofuranosyluracil; Base Sequence; Cytomegalovirus; Drug Evaluation, Preclinical; Ganciclovir; Herpes Simplex; Herpesvirus 1, Human; Herpesvirus 3, Human; Humans; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Promoter Regions, Genetic; Thymidine Kinase; Transformation, Genetic; Virulence; Virus Latency

1995
Automated sequential trace enrichment of dialysates combined with high-performance liquid chromatography and automated heart-cutting for the determination of the nucleoside 1-(beta-D-arabinofuranosyl)-5-(1-propynyl)uracil and its metabolite 5-propynylurac
    Journal of chromatography, 1994, Jan-14, Volume: 652, Issue:1

    Topics: Alkynes; Antiviral Agents; Arabinofuranosyluracil; Autoanalysis; Chromatography, High Pressure Liquid; Computers; Dialysis; Humans; Indicators and Reagents; Software; Spectrophotometry, Ultraviolet; Uracil

1994
Preliminary pharmacokinetics and safety of 882C87 in patients with herpes zoster.
    Journal of medical virology, 1993, Volume: Suppl 1

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antiviral Agents; Arabinofuranosyluracil; Female; Herpes Zoster; Humans; Male; Middle Aged

1993
Determination of 1-(beta-D-arabinofuranosyl)-5-(1-propynyl)-uracil and a metabolite, 5-propynyluracil, in plasma using ASTED (automated sequential trace enrichment of dialysates) combined, on-line, with high-performance liquid chromatography.
    Journal of chromatography, 1993, Jul-23, Volume: 617, Issue:1

    Topics: Alkynes; Antiviral Agents; Arabinofuranosyluracil; Chromatography, High Pressure Liquid; Dialysis; Humans; Reproducibility of Results; Uracil

1993
Pharmacokinetics of netivudine in haemodialysis patients.
    The Journal of antimicrobial chemotherapy, 1996, Volume: 38, Issue:5

    Topics: Antiviral Agents; Arabinofuranosyluracil; Humans; Kidney Diseases; Renal Dialysis

1996
Synthesis and evaluation of some masked phosphate esters of the anti-herpesvirus drug 882C (netivudine) as potential antiviral agents.
    Antiviral chemistry & chemotherapy, 1998, Volume: 9, Issue:3

    Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Cell Line; Esterases; Liver; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Phosphates; Prodrugs; Swine

1998